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Lesmahagow High School
Higher Human Biology
Unit 2 – Physiology and Health - Learning Outcomes
Part A – The Cardiovascular System
Key Area 5 – The structure and function of arteries, capillaries and
veins
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Describe the blood flow around the body (in general basic terms)
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Describe the structure of arteries and veins using the following
terms:
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Endothelium
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Central lumen
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Connective tissue
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Elastic fibres
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Smooth muscle
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Valves
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State the role of arteries, veins and capillaries
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State the function of valves
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Describe what happens to blood pressure as blood moves away
from the heart
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State what is meant by vasoconstriction and describe how it is
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State what is meant by vasodilation and describe how it is caused
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State the similarities and differences in composition between
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blood plasma and tissue fluid
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Describe the process of the exchange of materials between tissue
fluid and cells
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State what happens to the tissue fluid after pressure filtration
occurs
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State the role of the lymphatic vessels after pressure filtration
occurs
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Lesmahagow High School
Higher Human Biology
Unit 2 – Physiology and Health - Learning Outcomes
Part A – The Cardiovascular System
Key Area 6 – The structure and function of the heart
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Name the 4 chambers of the heart
Name the 4 valves in the heart
Describe the cause of heart sounds and how they can be heard
Name the 2 blood vessels which enter the heart and the 2 blood vessels
which leave the heart
Identify the above structures in a diagram
Describe the flow of blood in a heart
State the difference in the type of blood of blood found in each side of
the heart
Define the terms ‘cardiac output’, ‘heart rate’ and ‘stroke volume’
State the formula for cardiac output
Carry out cardiac output calculations
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State what is meant by the cardiac cycle
Define and describe what happens during atrial systole
Define and describe what happens during ventricular systole
Define and describe what happens during diastole
Describe the action of AV and SL valves during the cardiac cycle
Describe the changes in pressure during the cardiac cycle
Interpret graphs of pressure changes in heart and blood vessels
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Give another name for the pacemaker
Describe the action of the SAN on the cardiac muscle cells, including
how this stimulates the AVN
Identify SAN and AVN locations in a diagram
State the role of an ECG
Interpret ECG graphs in order to calculate heart rate
State that the heart beat can be regulated by both nervous and
hormonal control
State the role of medulla and the ANS
Name the 2 nerves that can release hormones
State the names of these 2 hormones and describe the effect they have
on the heart beat
State what blood pressure is
Describe how blood pressure can be measured
Explain how systolic and diastolic pressure are detected
State the typical blood pressure reading for a young adult
State what is meant by hypertension
State the link between by hypertension and coronary heart disease
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Lesmahagow High School
Higher Human Biology
Unit 2 – Physiology and Health - Learning Outcomes
Part A – The Cardiovascular System
Key Area 7 – Pathology of cardio vascular disease (CVD)
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Define the following terms:
• Atherosclerosis
• Atheroma
State the effects of a growing atheroma on the artery and blood
pressure
State 4 cardiovascular diseases caused by atherosclerosis
Define the following terms:
• Thrombus
• Thrombosis
• Embolus
Describe the role of clotting elements in the formation of scar
tissue, using the following terms:
• Prothrombin
• Thrombin
• Fibrinogen
• Fibrin
State how a stroke or heart attack can occur
State what is meant by peripheral vascular disease
State where in the body it can commonly occur and the conditions
that can occur as a result
State where cholesterol is synthesised
State the type of diet that can increase cholesterol levels in the
blood
Give 2 reasons why cholesterol is important for cellular functions
Define HDL and LDL
Describe the role of HDL in the body
Describe the role of LDL in the body
Describe the effect of the of the negative feedback response
when a cell has sufficient cholesterol levels
State what a high HDL to LDL ratio may result in
Describe 2 lifestyle choice which can improve the health of an
individual
Describe the role of ‘statins’
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Lesmahagow High School
Higher Human Biology
Unit 2 – Physiology and Health - Learning Outcomes
Part A – The Cardiovascular System
Key Area 8 – Blood glucose levels and obesity
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Describe the effect chronic elevation of blood glucose levels have
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on both endothelium and the blood vessels
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State a condition that may develop as a result of chronic elevated
blood glucose levels
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Name 3 diseases which can occur as a result of the above condition
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Name the 3 effects of small blood vessels being damaged by
elevated blood glucose levels
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Describe the role of pancreatic receptors and hormones (insulin,
glucagon, adrenaline) in negative feedback control of blood glucose
levels
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State the difference between type 1 and 2 diabetes in terms of
onset of condition and ability to produce insulin
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State the effect of high blood glucose levels on the kidneys and
the urine produced
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State the test which is used as an indicator of diabetes
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State the test which is used to diagnose diabetes
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Describe how this test would be carried out
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State 2 conditions obesity is major risk factor for
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State how obesity is characterised
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State what a body mass index is
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State how body fat can be measured
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Describe the link between exercise and diet
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State how risk factors for CVD can be reduced
Page 4 of 4