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Cells Early Microscopes -Lenses and microscopes: - Late 1500s – Italy: merchants develop magnifying lenses to examine the quality of cloth - 1600s – Holland: lenses combined to form microscopes and telescopes Early Microscopes -It was not until the mid-1600s that scientists began to use microscopes to observe living things -1665 – Robert Hooke (England) built compound microscope - looked at thin sections of cork - Under the microscope, cork seemed to be made of thousands of tiny, empty chambers Early Microscopes - Hooke called these chambers “cells” because they reminded him of a monastery's tiny rooms, which were called cells Early Microscopes - 1674 – Anton van Leeuwenhoek used a single-lens microscope to observe pond water - He used a single-lens microscope - The microscope revealed a fantastic world of tiny living organisms that seemed to be everywhere Early Microscopes - 1838 – Matthias Schleiden concluded that all plants are made of cells - 1839 – Theodor Schwann stated that all animals made of cells - 1855 – Rudolf Virchow observed onion root tip cells and concluded that new cells could only be produced by division of existing cells The Cell Theory - It became clear that cells are the basic unit of life - The cell theory grew out of the work of many scientists and improvements in the microscope. The Cell Theory - The Cell Theory has three principles: - All living things are made of cells The Cell Theory - The Cell Theory has three principles: - All living things are made of cells - Cells are the basic units of structure and function in living things The Cell Theory - The Cell Theory has three principles: - All living things are made of cells - Cells are the basic units of structure and function in living things - New cells are produced from pre-existing cells Prokaryotes vs Eukaryotes - Cells come in a great variety of shapes and an amazing range of sizes - All cells have two characteristics in common - They are surrounded by a barrier called a cell membrane - They contain the molecule that carries biological information—DNA Prokaryotes vs Eukaryotes - Cells fall into two broad categories, depending on whether they contain a nucleus - Nucleus: - A large structure with its own membrane that holds the cell’s genetic material (DNA) - The nucleus controls many of the cell's activities Prokaryotes vs Eukaryotes - Prokaryotes: - Cells that do NOT contain nuclei - Generally smaller and simpler - Do not have membrane-bound organelles - Have genetic material that is not contained in a nucleus - The organisms we call bacteria are prokaryotes Prokaryotes vs Eukaryotes - Eukaryotes: - Cells that do contain nuclei - Generally larger and more complex - Display great variety - Lives as single-celled organisms - Large, multicellular organisms - Dozens of structures and internal membranes, and - Plants, animals, fungi, and many are highly specialized protists - Contain a nucleus in which their genetic material is separated from the rest of the cell Prokaryotes vs Eukaryotes - Similarities between Prokaryotes & Eukaryotes: - Come in a variety of shapes and sizes - Both have DNA - All cells are enclosed by a membrane - All cells are filled with cytoplasm - Cells tend to be microscopic Exploring the Cell - Researchers use microscopes and techniques more powerful than the pioneers of biology could have imagined - Researchers can use fluorescent labels and light microscopy to follow molecules moving through the cell - Confocal light microscopy, which scans cells with a laser beam, makes it possible to build three-dimensional images of cells and their parts Images produced by light microscope Exploring the Cell - Electron microscopes are capable of revealing details as much as 1000 times smaller than those visible in light microscopes - Transmission electron microscopes (TEMs) make it possible to explore cell structures and large protein molecules Exploring the Cell - With scanning electron microscopes (SEMs), a pencillike beam of electrons is scanned over the surface of a specimen - The scanning electron microscope produces stunning three-dimensional images of cells Nerve broken open, revealing vesicles containing neurotransmitters Used toothbrush covered in plague Typical virus Prokaryotic vs Eukaryotic Reading, Video, & Double Bubble Thinking Map Prokaryotic Reading & Coloring Activity Parts of a Microscope & Microscope Lab Animal Cell & Plant Cell Doodle Notes Animal & Plant Cell Organelle Notes along with Flip Picture Book Cell Boundaries - All cells are surrounded by a thin, flexible barrier known as the cell membrane - Cell Membrane: thin, flexible barrier around a cell; regulates what enters and leaves the cell Cell Boundaries - The cell membrane regulates what enters and leaves the cell and also provides protection and support - Let’s Review! - Cell Membranes are made up of LIPIDS Cell Boundaries - What two monomers make up a LIPID? - Fatty Acid - Glycerol Cell Boundaries - Draw individual Lipids & Label their structures - Fatty Acid (Tails) Hydrophobic: Hates Water - Glycerol (Head) Hydrophilic : Likes Water Cell Membrane - The composition of nearly all cell membranes is a double-layered sheet called a lipid bilayer - Lipid Bilayer: - double-layered sheet that forms the core of nearly all cell membranes - hydrophilic heads point out, hydrophobic tails point inside Draw & Label the Lipid Bilayer Extracellular (Outside the cell) Hydrophilic “Heads”→ Hydrophobic “Tails”→ Intracellular (Inside the cell) Cell Membrane - In addition to lipids, most cell membranes contain protein molecules that are embedded in the lipid bilayer - Some of the proteins form channels and pumps that help to move material across the cell membrane - Carbohydrate molecules are attached to many of these proteins - Many of the carbohydrates act like chemical identification cards, allowing individual cells to identify one another Color & Label Cell Membrane Cell Walls - Many cells also produce a strong supporting layer around the membrane known as a cell wall - The main function of the cell wall is to provide support and protection for the cell - Cell walls are present in many organisms, including plants, algae, fungi, and many prokaryotes Cell Walls - Cell walls lie outside the cell membrane - Most cell walls are porous enough to allow water, oxygen, carbon dioxide, and certain other substances to pass through easily - Most cell walls are made from fibers of carbohydrate and protein Cell Walls - Plant cell walls are composed mostly of cellulose, a tough carbohydrate fiber - Cellulose is the principal component of both wood and paper Cell Wall Cell Membrane Doodle Notes Cell Transportation - Every living cell exists in a liquid environment that it needs to survive - One of the most important functions of the cell membrane is to regulate the movement of dissolved molecules from the liquid on one side of the membrane to the liquid on the other side Cell Transportation - The cytoplasm of a cell contains a solution of many different substances in water - Concentration: The mass of solute in a given volume of solution, or mass/volume Cell Transportation - Example: 12 grams of salt in 3 liters of water Concentration is 12 grams /3 Liters (g/L) THINK MATH: 12 / 3 is ? THEREFORE IT IS: 4 g/L Cell Transportation - Practice: 12 grams of salt in 6 liters of water Concentration is 12 grams /6 Liters (g/L) Final Concentration is : 2 g/L Cell Transportation - Which solution is more concentrated? 4 g/L 2 g/L Cell Transportation - In a solution, particles move constantly - Diffusion: process by which molecules tend to move from an area where they are more concentrated to an area where they are less concentrated - Molecules naturally move from HIGH concentration to LOW concentration Cell Transportation - The solution will eventually reach equilibrium - Equilibrium: when the concentration of a solute is the same throughout a solution - The substances will be evenly spaced out - Because diffusion depends upon random particle movements, substances diffuse across membranes without requiring the cell to use energy Cell Transportation - Even when equilibrium is reached, particles of a solution will continue to move across the membrane in both directions - Most biological membranes are selectively permeable - Selectively Permeable: Some substances can pass through the cell membrane while other substances cannot Also referred to as semipermeable membranes Diffusion Station for Notes Cell Transportation - Endocytosis: - process of taking material into the cell by means of infoldings, or pockets, of the cell membrane - Larger molecules and even solid clumps of material may be transported in through this process - Two types: Phagocytosis & Pinocytosis Cell Transportation - Phagocytosis: - process in which extensions of cytoplasm surround and engulf large particles and take them into the cell - It means “cell eating” Cell Transportation - Engulfing material in this way requires a considerable amount of energy - Due to this, it is correctly considered a form of active transport Cell Transportation - Pinocytosis: - process by which a cell takes in liquid from the surrounding environment - Tiny pockets form along the cell membrane, fill with liquid, and pinch off to form vacuoles within the cell Cell Transportation - Exocytosis: - process by which a cell releases large amounts of material outside the cell - The membrane of the vacuole surrounding the material fuses with the cell membrane, forcing the contents out of the cell Diffusion Lab