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Infection Control Student Orientation Basic, but important, Principles of Cross Transmission • Presence of microorganisms on hands or in environment does not necessarily = cross transmission or infection • Infection is multi-factorial requiring many cross – linkages • Epidemiologic Triangle: Tweeten SM. General principles of epidemiology. APIC Text, 2005 Healthcare associated infections (HAI)are the 4th leading cause of death in the U.S.after heart disease,cancer and stroke Hospital Acquired Infections • >2 million annually • >90,000 deaths annually • 20-30% are preventable How Do HAI Stack Up Against Other Adverse Events? • 3-7% of admissions have an adverse drug event • 140,000-180,000 deaths annually • $2 billion annually in excess costs • Cost > $3,000 each • Increase LOS by average of 2.2 days • • • • • • • • • 5% of admissions have HAI 88,000 deaths annually $4.6 billion excess $/yr $600/UTI $5000/pneumonia Up to $50,000/BSI Increase LOS 1-4 days/UTI, 7-8 days/SSI 7-21 days/BSI 7-30 days/pneumonia Sites of Nosocomial Infections Usual Causative Organisms • Urinary tract: E. Coli, Enterococcus species • Lower Respiratory (pneumonia or bronchitis): Klebsiella, Pseudomonas • Surgical Wounds: Staphylococci, Site dependent • IV: Staphylococci, not aureus Symptoms of Infection • abnormal labs diarrhea vomiting • temp : <97o>100o F. • chills/ sweats • Confusion mental changes • resp. secretions abnormal breath sounds • Cloudy, painful, foul smelling freq. Urination • cold extremities • redness, warmth, swelling rashes/boils • pain Normal Body Defenses • • • Mechanical: intact skin; mucous production; cilia, digestive enzymes, skin acidity etc. Nonspecific Responses: WBC phagocytic response, fever, inflammation, non-specific antibodies, t-cells for antigen binding Specific Response: Production of antigen-specific antibody, immunoglobulins The Hospitalized Patient: A Human at Risk • Break in the barrier of the skin • Tubes crossing mucous membranes • Medications altering the natural barriers of digestive pH/immune function • Decreased ability to use lung capacity • Foreign microbial environment • Disease processes of immune system Prevention of IV Catheter Related Infection • • • • • WASH HANDS Wear Gloves Cleanse Site: alcohol, air dry Do not re-palpate Choose appropriate catheter Prevention of Nosocomial Pneumonia • Patients at high risk for aspiration: – Ventilated patients – Patients with enteral tube – Patients with decreased gag-reflex • Interventions: – Maintain HOB @ 3045o angle if possible – Routinely check location of feeding tube – Routinely assess intestinal motility to avoid distention: bowel sounds, gastric vol. before tube feed Prevention of Nosocomial Pneumonia Cont. • Prevent Gastric Colonization • • • • Use agents for prophylaxis of gastric ulcers which do not raise the gastric pH Wear gloves during suctioning or contact w/respiratory secretions Use only sterile fluid for respiratory secretion removal (none when possible) Replace gloves with clean pair after contact w/ contaminated body site and before contact with respiratory tract. Prevention of Nosocomial Pneumonia Cont. • Postoperatively: – Cessation of smoking – Encourage coughing and deep breathing, incl. use of incentive spirometer – Early ambulation – Pain control- anlagesia and splinting – High risk patients: abdominal, head, neck or thoracic surgery; underlying resp. disease Prevention of Surgical Site Infections • Preoperative measures: – Free of remote infections – Preparation of the surgical site: prep agent, non-invasive removal of hair, prophylactic antibiotics Prevention of Surgical Site Infections Cont. • Intraoperatively: – Sterile technique – Limit trauma – Limit traffic in room Prevention of Surgical Site Infection Cont. • Postoperatively: – Aseptic wound care – Wound healed in 48-72 hours Sharps Injury Prevention: Examples of safetyEngineered sharps devices Hepatitis B – United States, 1978-2000 Decline among homosexual men Decline among IV drug users 30000 Cases 25000 20000 15000 10000 Hepatitis B vaccine licensed 5000 0 1978 1982 1986 1990 1994 1998 Exposure • Define Exposure: Blood or other potentially infectious material contact with non-intact skin or mucous membrane • > needlestick or cut/poke with sharp bloodbearing item • > splash to eyes, nose, or mouth What to do if you have an exposure to a bloodborne pathogen • Call Employee Health at 2-3297 for SJMH & SJMSH • Fill out green incident form and report to ER for SJMLH The Hierarchy of Precautions S tandard P recautions C ontact D roplet A irborne P recautions P recautions P recautions Standard Precautions: The Cornerstone of Infection Control Contact Precautions • Used for organisms difficult to treat (ex. Antibiotic Resistant Organisms-AROs) • Organisms which are able to be spread by environmental contamination Antibiotic Resistant Organisms • Methicillin Resistant Staphylococcus aureus (MRSA) (ICU ONLY AND ONLY FOR UNCONTAINED SITES) • Vancomycin Resistant Enterococcus (VRE) Organisms Which Can Be Spread Through Environmental Contamination • Respiratory Syncytial Virus • Clostridium difficile in a fecally incontinent patient Contact Precautions • GLOVES- worn whenever you enter the patient room; remove on exiting room • HANDWASHING- whenever you remove your gloves Contact Precautions • Private Room • Dedicate Equipment • Gown for substantial contact • (all except handwashing apply only to HCWs) Droplet Precautions • Large organisms spread by coughing, sneezing up to 3 foot away • Bacterial Meningitis (Neisseria meningitidis; Haemophilus influenza) • Whooping Cough (Bordetella pertussis) Droplet Precautions • Private Room • Mask Needed • Gowns, Gloves, and Patient Equipment the same as for Standard Precautions • Transport: Patient must wear mask Airborne Precautions • Illnesses where germs are expelled into the air by coughing, sneezing, laughing, etc. • Can be carried long distances in air and spread to others Airborne Precuations • Mycobacterium tuberculosis • Chickenpox (Varicella) • Measles (Rubeola) Airborne Precautions • Negative Pressure Room • Mask Required (for TB, N95 mask necessary) • Gowns, Eyewear , Gloves & Patient Equipment same as for SP • Transport: notify receiving unit; place mask on patient