Download Cinnamaldehyde application in the treatment of angina

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Transcript
Cinnamaldehyde application in the treatment of angina
Chinese cinnamon (cinnamaldehyde is the main active ingredient) is the commonly
used drug to treat heartache since ancient time. Experts from Shanghai University of
Chinese Medicine and Longhua Hospital had studied cinnamic aldehyde in the
treatment of angina pectoris in the application. Collect 241 prescriptions for the
treatment of headache from BC to 1911, involving a total of 303 kinds of drugs,
drug use, the total frequency of 1808, the average frequency of use of each drug is
5.97, which use the frequency to 81 cinnamon, arranged No. 1, dozens of times higher
than the average frequency of use frequently.
Compound containing cinnamon cure heartache, clinical governance experience,
experiments have supporting evidence. Modern research reports, 30 patients with
angina pectoris, service Shuguan pills (cinnamon, ginseng) for 4 weeks as a course of
treatment, 30 patients with the CSDP, treatment as above. .
. The treatment group and control group during the treatment efficacy is similar,
within 3 months after stopping the efficient treatment of angina and control groups
were 60.00% and 33.33%, two groups have significant differences.
Modern common type of nitroglycerin preparations could diastolic coronary
arteries, angina, but this alternative therapy the body in a passive state. Experts
believe that, because the body itself adjustment mechanism, exogenous supplement of
vasoactive substances on the one hand, including the environment caused by its
abnormal levels of volatility, The other hand, long-term use can cause the body
mechanism to adapt to state intervention, resulting in inhibition of cell secretory
function itself, may result in reduced ability to respond to the body, making the
required reaction time the reaction rate can not be met (such as occurs withdrawal
rebound ), which are detrimental to the body. Cinnamaldehyde adjustable release of
endogenous vasoactive substances, compared with alternative therapies, from the
mechanism we have advantage. Experts study also found that cinnamaldehyde protect
vascular endothelial cells, inhibit abnormal proliferation of vascular smooth muscle
cells and so on, to prevent the formation of atherosclerosis, angina root function,
long-term efficacy may be better.
Experts believe that the study of cinnamic aldehyde as the main raw material to
develop angina drugs have practical value.