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Paper 1 Q 2 DD of mass in rt iliac fossa (enumerate the most common causes and investigation) Right iliac fossa mass is a common clinical presentation and has a range of differentials that need to be excluded. Radiology plays an important role in this differentiation. Differential diagnosis appendicular mass o appendicular abscess o appendicular mucocele o appendicular neoplasma ileocaecal tuberculosis (hyperplastic type) intussusception carcinoma caecum tubo-ovarian mass, e.g. abscess and neoplasm undescended testis transplanted kidney ectopic kidney psoas abscess non-Hodgkin lymphoma rt iliac artery aneurysm Investigation: Laboratory CBC: leucocytosis in aappendicular abscess Leucopenia with TB o Tumour markers : ovarian tumours o PCR and tuberculin test :TB o o Blood film : lymphoma. Radiological o X ray :calcified lymph nodes in TB Obliteration of psoas shadow in appendicular abscess o o o o Ultrasound: distinguish a bowel mass from an ovarian or utrine mass, any lymph nodes or abnormal blood vessels. CT scan for abdominal wall masses and this would also be useful in looking at the extent of intra- abdominal malignant disease Intravenous contrast-enhanced CTscanning would clarify lower abdominal and pelvic vasculature. Pathological analysis by cytology for aspiration and histology for biopsies Paper 1 Q 8 DVT is a blood clot that has formed in a vein. Risk factores Surgery, trauma, burns ,Obesity ,Malignancy, Prolonged immobilization Diabetes, Inflammatory bowel disease Protein C, S, or antithrombin III deficiency Nephrotic syndrome, Polycythemia vera Dysfibrinogenemia , Acute leukemia, Infection Pregnancy, Oral estrogen therapy Sickle cell disease,Congestive heart failure Hemoglobinuria, Lupus anticoagulant disorder Varicose veins Behçet’s disease Homocysteinemia Investigations: 1. Doppler ultrasound: It is a simple and rapid method and is accurate in 8085% of cases. 2. Duplex ultrasound: This method combines Doppler ultrasound flow analysis with ultrasound imaging. Its sensitivity and specificity reach 90-100% 3. Ascending venography is the gold standard but it is invasive method. 4. 125I-fibrinogen uptake depends upon the incorporation of isotope labelled human serum fibrinogen into the developing thrombus. Any increase in radioactivity is detected with a scintillation counter. It is very accurate in the calf and lower thigh. 5. Other tests as plethysmography and venous pressure measurements are of academic interest. prophylaxis 1 . Physical measures to reduce venous stasis: a. Early ambulation after operations. b. Active leg exercise. c. Elastic stocking support especially in the elderly. d. Adequate postoperative hydration. e. Intermittent pneumatic external calf compression by special devices. f. Elevation of the foot of the bed. 2. Prophylactic anticoagulation: In high risk patients, one of two methods may be employed. A- Low dose unfractionated heparin 5000 IU subcutaneous 2 hours before operation and then every 12 hours until the patient is ambulant, It is proved to be very effective in lowering the incidence of DVT by 50%. B- Low molecular weight heparin (LMWH): Started the night before surgery and then given every 12 hours postoperatively. Dose: 20-40 mg SC every 12 hours according to body weight and degree of risk.