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Focused Ultrasound
- Lisa Howe
What is Focused Ultrasound?
• Early-stage
• Non-invasive
• Therapeutic technology
https://www.youtube.com/watch?v=Y73tVVmOjGg
What does that mean?
•
Depending on the design of the lens and the ultrasound parameters, the
target can be as small as 1x1.5mm or as large as 10x16mm in diameter.
Effects at focal point
•
Thermal ablation
• Focal drug delivery
• Blood-brain barrier opening
• Immunomodulation
• Neuromodulation
• Radiation sensitization
• Stem cell delivery
Brain Tumors
• NO CHEMOTHERAPY!
• NO NORMAL TISSUE DAMAGE!!
State of the Technology
State of the Technology
What this means for the future….
• Focused ultrasound could become an alternative to or complement
• Focused ultrasound could result in fewer complications such as:
• Focused ultrasound could shorten recovery time
Risks and Drawbacks
• Side effects
• http://www.sciencedirect.com/science/article/pii/S1474442213700486
• http://www.fusfoundation.org/
Focused Ultrasound
By Lisa Howe
• Early-stage
• Non-invasive
• Therapeutic technology
• Focused ultrasound
could shorten
recovery time
• Safer, more effective
treatment
• Reduce death,
disability, and
suffering
Focused ultrasound could become an
alternative to or complement:
• Traditional surgery
• Radiation therapy
• Drug delivery
Focused ultrasound could result in
fewer complications such as:
• Damage to normal tissue
• Infection
• Hemorrhage
• Pain
Effects of Focal Point:
• Thermal ablation
• Focal drug delivery
• Blood-brain barrier opening
• Immunomodulation
• Neuromodulation
• Radiation sensitization
• Stem cell delivery
Risks and Drawbacks
• postoperative paraesthesias
• deep vein thrombosis
• burns to the skin