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European Congress of Clinical Microbiology and Infectious Diseases 24th Barcelona, Spain 10 – 13 May 2014 ECCMID Final Programme www.eccmid.org Join us today – our commitment is infectious! – Become an ESCMID member – Then sign-up for Study Groups ! VISIT US WORLD SCMID IN THE E ID BARCELONA AT ECCM Good reasons for membership: • Society’s journals: CMI, NMNI • Registration discounts for events • Participation in Study Groups • ESCMID Newsletter and Yearbook • Discounts to other journals • Access to the Online Lecture Library and Membership Directory • Eligibility for ESCMID Awards, Research Grants and Observerships • Right to vote and participate in ESCMID Apply for Membership Visit our website and join us now! www.escmid.org/membership Address during the Congress 24th ECCMID Centre Convencions Internacional Barcelona (CCIB) Placa de Willy Brandt, 11-14 08019 Barcelona, Spain www.ccib.es Important Addresses 01 Acknowledgements03 Welcome Address 05 Congress Venue Overview 06 Committees09 Administrative Secretariat Kenes International 1-3 rue de Chantepoulet, PO Box 1726 1211 Geneva, Switzerland Phone: +41 22 908 0488 Fax: +41 22 906 9140 Email: [email protected] 18 23 24 25 Scientific Programme Saturday, 10 May 2014 27 Sunday, 11 May 2014 39 Monday, 12 May 2014 51 Tuesday, 13 May 2014 63 ePoster Sessions Sunday, 11 May 2014 Monday, 12 May 2014 ePosters Viewing Saturday, 10 May 2014 – Tuesday, 13 May 2014 87 Poster Sessions Saturday, 10 May 2014 Sunday, 11 May 2014 Monday, 12 May 2014 Tuesday, 13 May 2014 127 157 187 217 List of Chairpersons List of Speakers & Authors Instructions for Speakers & Authors 248 251 313 Integrated Symposia 314 Industrial Exhibition Overview List of Exhibitors Exhibitors’ Guide 327 328 331 Opening Ceremony and Networking Reception General Information A – Z Future Congresses 360 361 362 ePosters 77 81 Posters Scientific Secretariat 24th ECCMID c/o ESCMID Executive Office P.O. Box 214 4010 Basel, Switzerland Phone: +41 61 508 01 50 Email: [email protected] Scientific Programme Overview CME Accreditation Introduction to the Scientific Programme ESCMID Study Groups and Business Meetings Chairs, Speakers & Authors ECCMID Deputy Programme Director Prof Winfried V. Kern Division of Infectious Diseases Albert-Ludwigs-University Hugstetter Strasse 55 79106 Freiburg, Germany 12 Exhibition ECCMID Programme Director Prof Dr Jordi Vila Estape Head of the Department of Clinical Microbiology Hospital Clinic School of Medicine, University of Barcelona Villarroel, 170 08036 Barcelona, Spain Awards, Grants and Fellowships 2014 www.eccmid.org 24th ECCMID / Barcelona Final Programme 01 General Information ESCMID President Prof Gunnar Kahlmeter Dept. of Clinical Microbiology Central Hospital 351 85 Växjö, Sweden Awards TABLE OF CONTENTS Overview & Programme IMPORTANT ADDRESSES Introduction Final Programme of the 24th ECCMID in Barcelona, Spain 10 – 13 May 2014 Forthcoming Events Postgraduate Education Courses and Workshops ESCMID Summer School Receive state-of-the-art knowledge from expert educators. Gather hands-on experience in your field of interest. Discuss your work with senior and peer colleagues. An intense one-week course covering diverse topics in the infection field. The high faculty-student ratio and the high level of interactivity make it so popular. 30 Jun – 4 Jul 2014 Molecular Typing Methods for Pathogens Lyon, France ESCMID Postgraduate Education Course 4 – 6 Jul 2014 Bringing PK and PD in Fungal Infections into the Clinic Nijmegen, The Netherlands ESCMID Postgraduate Education Course 16 – 19 Sep 2014 22 – 24 Sep 2014 Infectious Diseases in the Mediterranean and the Middle East: Current Challenges Izmir, Turkey ESCMID Postgraduate Education Course 29 Sep – 1 Oct 2014 Anaerobic Bacteria: Next Generation Technology Meets Anaerobic Diagnostics Groningen, The Netherlands ESCMID Postgraduate Technical Workshop 2 – 3 Oct 2014 Infection Management in the Elderly: Room for Improvement Annecy, France ESCMID Postgraduate Education Course 6 – 8 Oct 2014 Advanced Antimicrobial Pharmacokinetic and Pharmacodynamic Modelling and Simulation Liverpool, United Kingdom ESCMID Postgraduate Technical Workshop 16 – 17 Oct 2014 02 3rd Workshop on Antimicrobial Susceptibility Testing and Surveillance Linz, Austria ESCMID Postgraduate Technical Workshop Mobility and Infection: Diagnosis and Management Dubrovnik, Croatia ESCMID Postgraduate Education Course 20 – 23 Oct 2014 ESCMID-SHEA Training Course in Hospital Epidemiology Phuket, Thailand 29 – 31 Oct 2014 Acute Infectious Encephalitis: Challenges in Clinical and Biological Diagnosis Grenoble, France ESCMID Postgraduate Education Course 7 – 8 Nov 2014 How to Design and Perform your Clinical Studies in Infectious Diseases and Clinical Microbiology Tübingen, Germany ESCMID Postgraduate Education Course 24th ECCMID / Barcelona Final Programme 5 – 12 Jul 2014 13th ESCMID Summer School Sigtuna, Sweden ESCMID Conferences Get the latest news about your field of work delivered from selected experts. Exchange ideas with your colleagues on hot topics. 5 – 6 Jun 2014 3rd ESCMID Workshop on Professional Affairs in Clinical Microbiology and Infectious Diseases Ljubljana, Slovenia 19 – 20 Sep 2014 Infections and their Prevention Beijing, China 22 – 24 Oct 2014 Reviving Old Antibiotics Vienna, Austria 6 – 8 Mar 2015 Vaccines for Mutual Protection Lisbon, Portugal Future ECCMIDs 25 – 28 Apr 2015 25th ECCMID Copenhagen, Denmark 9 – 12 Apr 2016 26th ECCMID Istanbul, Turkey 22 – 25 Apr 2017 27th ECCMID 21 – 24 Apr 2018 28th ECCMID n d informatio More detaile ebsi te: w ID M the E S C on d n u fo e b can .org w w w.escmid Acknowledgements The ECCMID Programme Committee is proud to acknowledge the scientific input from the following organisations in setting up the scientific programme and/or organising joint workshops and symposia: Platinum Sponsors ASM – American Society for Microbiology, Programme Committee of the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) Making sense of our relationships with mucosal commensals and pathogens (page 49) Gold Sponsors Introduction The Organising Committee expresses its thanks and appreciation to all who have generously contributed to the success of the 24th European Congress of Clinical Microbiology and Infectious Diseases: EAACI – European Academy of Allergy and Clinical Immunology ESCMID guidelines for diagnosis and treatment of Aspergillus diseases (page 31) EACS – European AIDS Clinical Society Cryptococcal infections in HIV-infected patients: what is new in 2014? (page 59) Awards EANM – European Association of Nuclear Medicine Infections and devices: imaging & nuclear medicine meets infectious diseases (page 50) ECMM – European Confederation of Medical Mycology ESCMID guidelines for diagnosis and treatment of Aspergillus diseases (page 31) Overview & Programme ECDC – European Centre for Disease Prevention and Control Ins and outs of Legionnaires Disease (page 50) Laboratory response to emerging viral diseases: from pathogen discovery to disease monitoring (page 36) ERS – European Respiratory Society ESCMID guidelines for diagnosis and treatment of Aspergillus diseases (page 31) ePosters EUCAST – European Committee on Antimicrobial Susceptibility Testing Antimicrobial susceptibility testing with EUCAST breakpoints and methods (page 29) EUCAST questions and answers (page 51) European Commission Antimicrobial resistance research, supported by funding from the EU and the US NIH/NIAID (page 63) Posters ICHS – International Immunocompromised Host Society What is new in immunocompromised patients? (page 64) Chairs, Speakers & Authors IDSA – Infectious Diseases Society of America Clinical Grand Round 2014 (page 64) ISF – International Sepsis Forum What’s new in sepsis in 2014 (page 32) The MSG – Mycoses Study Group of the International Society for Human and Animal Mycology Predicting the future in fungal diagnosis and therapy (page 60) UEMS – European Union of Medical Specialists (Infectious Disease and Medical Microbiology Section) Training in infection in Europe – progress in curricula and assessments (page 46) US NIAID – United States National Institute of Allergy and Infectious Diseases Antimicrobial resistance research, supported by funding from the EU and the US NIH/NIAID (page 63) 24th ECCMID / Barcelona Final Programme 03 Exhibition SAM – Society for Anaerobic Microbiology Two-faced companions: highlights in the world of anaerobes (page 74) General Information Silver Sponsors ESCMID presents: ECCMID Infection Control Highlights Saturday, 10 May 2014 Monday, 12 May 2014 Educational Workshop: 08.45 – 10.45 h, Hall B EW01: Infection prevention and management in long-term care facilities Chairpersons: Sheldon Stone (UK), Leonardo Pagani (CH) Meet-the-Expert Session: 07.45 – 08.45 h, Hall J Current challenges and emerging evidence of infection control and prevention measures in long-term care facilities Experts: Maria Luisa Moro (IT), Beatrice Jans (BE) 2-hour Oral Session: 13.30 – 15.30 h, Hall E Lessons learned from Clostridium difficile molecular epidemiology Chairpersons: Mark H. Wilcox (UK), Ed J. Kuijper (NL) 2-hour Oral Session: 09.00 – 11.00 h, Hall H Outbreaks of MDR Gram-negative bacteria: what works and what does not work? Chairpersons: Barry Cookson (UK), Anna-Pelagia Magiorakos (SE) 2-hour Symposium: 13.30 – 15.30 h, Hall I Application of new methods in medical microbiology and infection control Chairpersons: Frederic Laurent (FR), Francois Vandenesch (FR) Keynote Lecture: 14.30 – 15.30 h, Hall J On the cutting edge of infection control research: what to do when evidence is missing? Speaker: Leonard A. Mermel, USA 2-hour Symposium: 16.30 – 18.30, Hall J Carbapenemases from prevention to treatment Chairpersons: Luis Martinez-Martinez (ES), Marek Gniadkowski (PL) 2-hour Symposium: 16.30 – 18.30, Hall A Implementing international guidelines to reduce the spread of MDR Gram-negatives at national level Chairpersons: Uwe Frank (DE), Achilleas Gikas (GR) 2-hour Symposium: 16.00 – 18.00 h, Hall H New approaches to prevent transmission of Clostridium difficile infections Chairpersons: Ed J. Kuijper (NL), Franz Allerberger (AT) Sunday, 11 May 2014 Tuesday, 13 May 2014 Meet-the-Expert Session: 07.45 – 08.45 h, Hall D Outbreak of P. aeruginosa in your hospital and you think it could be water-related? Want to know what to do next? Experts: Michael Weinbren (UK), Matthias Trautmann (DE) Meet-the-Expert Session: 07.45 – 08.45 h, Hall C Control of vancomycin-resistant enterococci: efforts justified? Experts: Markus Dettenkofer (DE), Luisa M. V. Peixe (PT) Meet-the-Expert Session: 07.45 – 08.45 h, Hall I Screening for carbapenemase production, molecular and phenotypic methods Experts: Laurent Poirel (CH), Christian G. Giske (SE) 2-hour Symposium: 09.00 – 11.00 h, Hall A What is new on surgical site infection prevention? Chairpersons: Werner Zimmerli (CH), Jean-Christophe Lucet (FR) 1-hour Symposium: 14.30 – 15.30 h, Hall A The year in Infection Control Chairperson: Jan A.J.W. Kluytmans (NL) Speakers: Barry Cookson (UK), Christina Vandenbroucke-Grauls (NL) 04 2-hour Oral Session: 16.00 – 18.00 h, Hall D New transmission routes and genotypic diversity: are we looking at a new MRSA? Chairpersons: Stephan J. Harbarth (CH), Benito Almirante (ES) 24th ECCMID / Barcelona Final Programme 2-hour Oral Session: 09.00 – 11.00 h, Hall F Healthcare-associated infections – from analysis to interventions Chairpersons: Susan S. Huang (USA), Khetam Hussein (IL) 1-hour Symposium: 11.30 – 12.30 h, Hall C Surveillance of healthcare-associated infections: infections or procedures? Chairpersons: Hanan Balkhy (SA), Khetam Hussein (IL) 2-hour Symposium: 13.30 – 15.30 h, Hall C Antimicrobial prophylaxis of surgical site infections: time to review? Chairpersons: Joseph S. Solomkin (USA), Matthew Dryden (UK) 2-hour Symposium: 13.30 – 15.30 h, Hall A Controlling transmission of multidrug-resistant pathogens in the intensive care unit Chairpersons: Francesco Menichetti (IT), Jose Antonio Martinez Martinez (ES) Welcome Address Dear Colleagues and Friends, Introduction It is our great pleasure and privilege to be your hosts at the 24th European Congress of Clinical Microbiology and Infectious Diseases in Barcelona, Spain. Over the past several years, ECCMID has rapidly grown to become the world´s largest congress in the field of clinical microbiology and infectious diseases and in Barcelona we expect 10,000 delegates or more. In addition, ECCMID also offers various activities in many related fields such as infection control and vaccines. The Programme Committee has prepared a series of educational workshops, symposia, meet-the-expert sessions, poster- and oral sessions in many parallel tracks to keep you very busy for 4 days. We encourage you to join one or more of our many Study Groups and to visit the exhibition Awards where companies present tomorrow´s equipment and therapeutics. ECCMID now hosts the most comprehensive exhibition of new equipment and diagnostics in the field for large and small laboratories. Barcelona’s International Convention Centre forms part of the new technological and business district known as “22@”, one of Overview & Programme the city’s best developed urban areas, which includes a selection of hotels and communications and transport network that seamlessly connects it to the rest of the city. Modern installations, architectural beauty and seaside location makes Barcelona’s International Convention Centre truly unique as one of the largest convention centres in Southern Europe. With a surface area of 100,000 sqm including the Convention Centre and the Forum Auditorium, the centre can welcome up to 15,000 delegates. Exhibition Prof Winfried V. Kern ECCMID Deputy Programme Director 24th ECCMID / Barcelona Final Programme 05 General Information Prof Jordi Vila Prof Gunnar Kahlmeter ECCMID Programme Director ESCMID President Chairs, Speakers & Authors Posters ePosters We wish you a fruitful meeting and a wonderful stay in Barcelona. H I J Congress Venue Overview LEVEL 0 n To hall A tra En nce tra En nce tra N ITIO HIB Po st er s EX ID CM ES ORLD W gi Re n atio str nce tra En En nce C h Ex tio i b i A B LEVEL LEVEL 2 0 LEVEL 1 24th ECCMID LEVEL 1 European Congress of Clinical Microbiology and Infectious Diseases 127 128 Barcelona, Spain, 10 - 13 May 2014 125 124 129 130 131 132 133 134 123 122 The Congress of 121 120 118 D 119 J I H G F E m rs ake y Roo e p S ead R 06 24th ECCMID / Barcelona Final Programme LEVEL 0 Congress Venue Overview LEVEL 2 Overview & Programme Po st er s Awards C Introduction LEVEL 2 129 130 131 132 133 134 123 122 118 D 119 Chairs, Speakers & Authors 121 120 LEVEL 0 M218 M219, M220 M221 24th ECCMID / Barcelona M211 M212 M217 Final Programme Exhibition M213 M214 Press Room M219, M220 I H G F E m rs ake y Roo e p S ead R 07 General Information 125 124 Posters 127 128 ePosters LEVEL 1 J MEZZANINE LEVEL ESCMID presents: EUCAST at ECCMID Barcelona Saturday, 10 May 08.45 – 12.45, Hall A Educational Workshop Antimicrobial susceptibility testing with EUCAST breakpoints and methods. Susceptibility testing of infrequently isolated fastidious organisms. L. Martinez-Martinez, Spain Update on EUCAST 2014. R. Canton Moreno, Spain 15.30 – 16.30, Poster Exhibition Hall Poster session I EUCAST Antimicrobial susceptibility testing Update on EUCAST methods and breakpoints. G. Kahlmeter, Sweden Internal quality control. R. L. Skov, Denmark External quality assessment. D.F.J. Brown, United Kingdom Moderated panel discussion on questions from the audience (part 1). A. P. MacGowan, United Kingdom Susceptibility testing systems – are some more equal than others? J. D. Turnidge, Australia Issues in testing susceptibility to beta-lactam / beta-lactamase inhibitor combinations. R. Howe, United Kingdom Moderated panel discussion on questions from the audience(part 2). A. P. MacGowan, United Kingdom Monday, 12 May 07.45 – 08.45, Hall D Meet the Experts EUCAST questions and answers D.F.J. Brown, United Kingdom, E. Matuschek, Sweden 12.45 – 14.15, Meeting Room 122/123 EUCAST General Committee Meeting 16.30 – 18.00, Meeting Room 122/123 EUCAST AFST General Committee Meeting EUCAST is a standing committee jointly organised by ESCMID, ECDC (European Centre for Disease Prevention and Control) and European national breakpoint committees. Visit EUCAST representatives at the EUCAST booth in the ESCMID World at ECCMID Barcelona! Sunday, 11 May: 12.30–13.30 Monday, 12 May: 12.30–13.30 Tuesday, 13 May: 12.30–13.30 Committees Michel Drancourt, Marseille, France (NMNI Editor-in-Chief) Giuseppe Cornaglia, Verona, Italy (Past President & Communications Officer) William Hope, Liverpool, United Kingdom (Medical Guidelines Director) Cornelia Lass-Flörl, Innsbruck, Austria (Treasurer) Didier Raoult, Marseille, France (CMI Editor-in-Chief) Mario Poljak, Ljubljana, Slovenia (Professional Affairs Officer CM) Jordi Vila Estape, Barcelona, Spain (ECCMID Programme Director) Awards Murat Akova, Ankara, Turkey (President-elect, Sec. General & Scientific Affairs Officer) Overview & Programme Rafael Canton, Madrid, Spain (EUCAST Chairman) ePosters Gunnar Kahlmeter, Växjö, Sweden (President) Introduction ESCMID Ad-hoc Executive Committee Members Chairs, Speakers & Authors Posters Jesús Rodríguez-Baño, Seville, Spain (Education Officer) Evelina Tacconelli, Tübingen, Germany (Professional Affairs Officer ID) Exhibition New ESCMID Executive Committee Annelies Zinkernagel, Zurich, Switzerland 24th ECCMID / Barcelona Final Programme 09 General Information ESCMID Executive Committee Committees ECCMID Programme Committee Jordi Vila Estape, Barcelona, Spain (ECCMID Programme Director) Winfried V. Kern, Freiburg, Germany (ECCMID Deputy Programme Director) Murat Akova, Ankara, Turkey Emmi Andersson, Stockholm, Sweden Jordi Carratala, Barcelona, Spain Elisa Cordero Matias, Seville, Spain Giuseppe Cornaglia, Verona, Italy Carmen-Michaela Cretu, Bucharest, Romania Alexander W. Friedrich, Groningen, The Netherlands Johan Giesecke, Stockholm, Sweden – ECDC Gilbert Greub, Lausanne, Switzerland Hans H. Hirsch, Basel, Switzerland Po-Ren Hsueh, Taipei, Taiwan Gunnar Kahlmeter, Växjö, Sweden Cornelia Lass-Flörl, Innsbruck, Austria Marc Lecuit, Paris, France Rogelio Lopez-Velez, Madrid, Spain Alasdair MacGowan, Bristol, UK Surbhi Malhotra-Kumar, Antwerp, Belgium Luis Martinez-Martinez, Santander, Spain Patricia Munoz Garcia, Madrid, Spain Alvaro Pascual Hernandez, Seville, Spain Mical Paul, Petah-Tiqva, Israel Nicola Petrosillo, Rome, Italy Mario Poljak, Ljubljana, Slovenia Didier Raoult, Marseille, France Guénaël Rodier, Geneva, Switzerland – WHO Europe Jesús Rodríguez-Baño, Seville, Spain Alex Soriano, Barcelona, Spain Evelina Tacconelli, Tübingen, Germany Andrew J. Ullmann, Würzburg, Germany Maria Virginia Villegas, Cali, Columbia Annelies Zinkernagel, Zurich, Switzerland ESCMID Education Subcommittee (ES) Jesús Rodríguez-Baño, Seville, Spain (Chair) Emmi Andersson, Stockholm, Sweden Sibel Ascioglu, Ankara, Turkey Kanita Dedic, Bihac, Bosnia and Herzegovina (Ad-hoc) Alejandro Martin-Quiros, Madrid, Spain (Ad-hoc) Dorothea Orth, Innsbruck, Austria Tibor Pál, Al Ain, United Arab Emirates Eskild Petersen, Aarhus, Denmark Céline Pulcini, Nice, France Bernd Salzberger, Regensburg, Germany Maurizio Sanguinetti, Rome, Italy Maria Souli, Athens, Greece ESCMID Scientific Affairs Subcommittee (SAS) Murat Akova, Ankara, Turkey (Chair) Maiken Cavling Arendrup, Copenhagen, Denmark Hanan Balkhy, Riyadh, Saudi Arabia Rosemary Barnes, Cardiff, UK German Bou Arevalo, La Coruña, Spain Birgitta Evengård, Umeå, Sweden Marek Gniadkowski, Warsaw, Poland Hervé Pelloux, Grenoble, France Hakan Leblebicioglu, Samsun, Turkey Paul Savelkoul, Amsterdam, The Netherlands 10 24th ECCMID / Barcelona Final Programme ESCMID Professional Affairs Subcommittee (PAS) Mario Poljak, Ljubljana, Slovenia (Chair, CM) Evelina Tacconelli, Tübingen, Germany (Chair, ID) Guido Antonelli, Rome, Italy Petra Apfalter, Linz, Austria Bridget Atkins, Oxford, UK Nicholas John Beeching, Liverpool, UK Maria Adriana Cataldo, Rome, Italy Hilary Humphreys, Dublin, Ireland Khetam Hussein, Haifa, Israel Ulrik Stenz Justesen, Odense, Denmark Piotr Kochan, Cracow, Poland Truls Michael Leegaard, Lørenskog, Norway Endre Ludwig, Budapest, Hungary Mario Umberto Mondelli, Pavia, Italy (UEMS ID Section Representative) Leonardo Pagani, Bolzano, Italy Pilar Retamar Gentil, Seville, Spain Katja Seme, Ljubljana, Slovenia Hilpi Rautelin, Uppsala, Sweden Andrej Trampuz, Berlin, Germany Andrew J. Ullmann, Würzburg, Germany ESCMID Publication Subcommittee (PS) Giuseppe Cornaglia, Verona, Italy (Chair) Rupert Cousens, Chichester, UK Michel Drancourt, Marseille, France Didier Raoult, Marseille, France Parity Commission (PC) Evelina Tacconelli, Tübingen, Germany (Chair) Mario Poljak, Ljubljana, Slovenia (Chair) Nur Benzonana, Istanbul, Turkey Titia M. Kortbeek, Bilthoven, The Netherlands Dan Otelea, Bucharest, Romania Trainee Association of ESCMID (TAE) Polona Maver Vodicar, Ljubljana, Slovenia (Chair) Joana Cortez, Coimbra, Portugal Chrysanthi Skevaki, Athens, Greece Davorka Dusek, Zagreb, Croatia Kanita Dedic, Bihac, Bosnia and Herzegovina Alejandro Martin-Quiros, Madrid, Spain Committees Clinical Parasitology (ESGCP) www.escmid.org/esgcp Titia M. Kortbeek, Bilthoven, The Netherlands [email protected] Clostridium difficile (ESGCD) www.escmid.org/esgcd Ed J. Kuijper, Leiden, The Netherlands [email protected] Critically Ill Patients (ESGCIP) www.escmid.org/esgcip Jordi Rello, Barcelona, Spain [email protected] Elderly Infections (ESGIE) www.escmid.org/esgie Mical Paul, Haifa, Israel [email protected] Epidemiological Markers (ESGEM) www.escmid.org/esgem Alexander W. Friedrich, Groningen, The Netherlands [email protected] Food/Water Infections (EFWISG) www.escmid.org/efwisg Kevin Kerr, Harrogate, UK [email protected] Fungal Infection (EFISG) www.escmid.org/efisg Andrew J. Ullmann, Würzburg, Germany [email protected] Helicobacter (EHSG) www.escmid.org/ehsg Giovani Gasbarrini, Rome, Italy [email protected] Immunocompromised Hosts (ESGICH) www.escmid.org/esgich José Maria Aguado, Madrid, Spain [email protected] Introduction Awards Mycobacterial Infections (ESGMYC) www.escmid.org/esgmyc Emmanuelle Cambau, Paris, France [email protected] Overview & Programme Brain Infections (ESGIB) www.escmid.org/esgib Stephen Leib, Berne, Switzerland [email protected] Molecular Diagnostics (ESGMD) www.escmid.org/esgmd Paul Savelkoul, Amsterdam, The Netherlands [email protected] Mycoplasma Infections (ESGMI) www.escmid.org/esgmi Cecile Bebear, Bordeaux, France [email protected] Nosocomial Infections (ESGNI) www.escmid.org/esgni Barry D. Cookson, London, UK [email protected] ePosters Bloodstream Infections (ESGBIS) www.escmid.org/esgbis Jesús Rodríguez-Baño, Seville, Spain [email protected] Lyme Borreliosis (ESGBOR) www.escmid.org/esgbor Gerold Stanek, Vienna, Austria [email protected] PK/PD of Anti-Infectives (EPASG) www.escmid.org/epasg Ursula Theuretzbacher, Vienna, Austria [email protected] Resistance Surveillance (ESGARS) www.escmid.org/esgars Patrice Nordmann, Fribourg, Switzerland [email protected] Posters Biofilms (ESGB) www.escmid.org/esgb Thomas Bjarnsholt, Copenhagen, Denmark [email protected] Legionella Infections (ESGLI) www.escmid.org/esgli Jeroen den Boer, Haarlem, The Netherlands [email protected] Staphylococci (ESGS) www.escmid.org/esgs Francois Vandenesch, Bron, France [email protected] Chairs, Speakers & Authors Antibiotic Policies (ESGAP) www.escmid.org/esgap Dilip Nathwani, Dundee, UK [email protected] Intracellular Bacteria (ESCAR) www.escmid.org/escar Amel Letaief, Sousse, Tunisia [email protected] Travel and Migration (ESGITM) www.escmid.org/esgitm Hakan Leblebicioglu, Samsun, Turkey [email protected] Vaccines (EVASG) www.escmid.org/evasg Susanna Esposito, Milan, Italy [email protected] Exhibition Anaerobic Infections (ESGAI) www.escmid.org/esgai Elisabeth Nagy, Szeged, Hungary [email protected] Implant Infections (ESGIAI) www.escmid.org/esgiai Andrej Trampuz, Berlin, Germany [email protected] Viral Hepatitis (ESGVH) www.escmid.org/esgvh Joop Arends, Utrecht, The Netherlands [email protected] 24th ECCMID / Barcelona Final Programme 11 General Information ESCMID Study Groups Awards and Grants 2014 ESCMID Award for Excellence in Clinical Microbiology and Infectious Diseases 2014 Ilaria Capua Ilaria Capua is currently a Member of the Italian Parliament and Vice-President of the 7th Parliamentary Commission for Culture, Science and Education. Therefore, she has taken a leave of absence from her position as Director of the Division of Comarative Biomedical Sciences at the Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro (Padua), Italy; her division hosts the Food and Agriculture Organization of the United Nations (FAO), the World Organization for Animal Health (OIE) Reference Laboratories for animal and avian influenzas and Newcastle disease, rabies and the OIE Collaborating Centre for Diseases at the Human-Animal Interface. She is also a visiting professor at the Centre for Virus Research at the University of Glasgow. Her group in Legnaro of over 70 staff provides diagnostic expertise globally and conducts cutting-edge research on influenza viruses and viral zoonoses. She has extensive experience in coordinating international research projects funded by the European Commission, and has also worked closely with FAO, managing Technical Cooperation Projects covering 40 countries, and with OIE in international activities and twinning projects. She is author or co-author of over 200 publications in peer-reviewed journals as well as editor of scientific books and of books and articles for the general public. In 2006 she ignited an international debate on enhancing interdisciplinary collaboration to foster transparency of genetic data of influenza viruses, which has promoted a review of international health policies on data sharing to improve pandemic preparedness. In 2007 she was among the winners of the Scientific American 50 Award and, in 2008, was included among Seed Magazine’s Revolutionary Minds for leadership in science policy. She is the first female recipient of the Penn Vet World Leadership in Animal Health Award, the most prestigious award in veterinary medicine (2011). In 2012 she became a Grande Ufficiale della Repubblica Italiana, the Order of Merit of the Italian Republic awarded by the Italian President. 12 24th ECCMID / Barcelona Final Programme Research interests Her areas of research include viral diseases of birds, mammals and fish, with particular reference to zoonotic viral infections. Her group is actively involved in the epidemiology, evolution and phylogeny of avian influenza viruses and in the development of novel vaccines for influenza infections. In addition, studies on interspecies transmission mechanisms and on the metabolic consequences of influenza infection have become core parts of her research activities. The group also functions as an international reference laboratory for rabies and lyssaviruses, which is involved in molecular evolution studies and the development of novel control and prevention strategies. Other areas of interest include diagnosis and control of Newcastle disease and coronavirus infections in poultry, pathogenesis and vaccine development for viral diseases of fish and poultry and research on selected viral zoonotic agents, including astroviruses, West Nile virus and related flaviviruses. The application and integration of advanced tools in molecular genetics and bioinformatics for research focusing on infectious diseases at the animal-human interface is also a key activity of her group. Ilaria Capua will be presented with her award during the ESCMID Excellence Award ceremony by Gunnar Kahlmeter, ESCMID President, and Giuseppe Cornaglia, ESCMID Past President, on Monday, 12 May 2014, 14.30 – 15.30 in Hall C. During this ceremony she will give her recipient's lecture: ‘Close encounters of the third kind – pathogens and globalisation’. Michael Ramharter will be presented with his award during the ESCMID Young Investigator Awards Session on 13 May 2014 at 11.30 – 12.30 in Hall E. During the session, he will present his work: ‘Development of antimalarial drugs in Lambaréné, Gabon’. Joost Wiersinga will be presented with his award during the ESCMID Young Investigator Awards Session on 13 May 2014 at 11.30 – 12.30 in Hall E. During the session, he will present his work: ‘Gut-lung axis: the intestinal microbiota in pneumonia’. 24th ECCMID / Barcelona Final Programme 13 Overview & Programme ePosters Posters Chairs, Speakers & Authors Research Interests He investigates innate immune responses in sepsis, with a special interest in sepsis caused by Streptococcus pneumoniae, Klebsiella pneumoniae, Burkholderia pseudomallei and Salmonella typhi. Recent interests include the role of gut microbiota during severe bacterial infections and optimisation of antibiotic therapy for – among others – cellulitis / erysipelas. He currently steers the European Sepsis Academy grant initiative and the European Melioidosis Network. His work has been published in Nat Rev Microbiol, PLoS Pathog, PLoS Medicine, N Engl J Med and other journals. Exhibition Research Interests Starting from the preclinical evaluation of antimalarial drugs, he developed a strong interest in the clinical development of antimalarial combination therapies. He has led a series of clinical trials investigating novel drugs and drug combinations for the treatment and prevention of malaria in children and pregnant women – two of the most vulnerable patient populations in sub-Saharan Africa. Besides malaria, his main research activities focus on the epidemiology and management of neglected tropical diseases including schistosomiasis and echinococcosis and other infectious diseases occurring in the tropics. Joost Wiersinga He received his medical training at the University of Amsterdam (The Netherlands) with additional courses at the Mayo Clinic (Rochester, MN) and the National Institutes of Health (NIH, Bethesda, MD). He achieved his PhD on the topic ‘On Toll-like receptors and the innate immune response in sepsis caused by Burkholderia pseudomallei (melioidosis)’, cum laude under the guidance of Professor Tom van der Poll (University of Amsterdam) and Professor Sharon Peacock (University of Oxford); during this period he worked in Thailand at the Wellcome Trust South-East Asia Major Overseas Programme in Bangkok. Previous awards won by him are the O'Callaghan PhD Award, the Andreas Bonn Medallion and the GSK ICAAC Award. At the moment, he divides his time between patient care at the Department of Medicine (sub-specialty Infectious Diseases), teaching and research in the Center for Experimental Molecular Medicine (CEMM) and the Center for Infection and Immunity (CINIMA), all at the Academic Medical Center, University of Amsterdam, The Netherlands. General Information Michael Ramharter He is Associate Professor at the Medical University of Vienna, Austria, and leader of the Infectious Disease Control Group – a scientific working group co-affiliated to the Institut für Tropenmedizin, Universität Tübingen, and the Centre de Recherches Médicales de Lambaréné in the Central African country of Gabon. Early in his career he worked under the guidance of Walther H. Wernsdorfer on the preclinical development of anti-malarials in the Thai-Myanmar border region – an experience which sparked an ever-increasing interest in the clinical investigation of infectious diseases in the tropics. He shifted the focus of his work to Central Africa when he joined Professor Peter G. Kremsner’s team at the Centre de Recherches Médicales de Lambaréné, at the Albert Schweitzer Hospital in Gabon. He has held postdoctoral positions at the Institut für Tropenmedizin, Universität Tübingen, and the Institut Pasteur, Université de la Méditerranée, Marseille, France. He currently works as a specialist in Internal Medicine and consultant in Infectious Diseases and Tropical Medicine at the Division of Infectious Diseases and Tropical Medicine headed by Professor Wolfgang Graninger. Awards ESCMID Young Investigator Awards for Research in Clinical Microbiology and Infectious Diseases 2014 ESCMID Research Grants 2014 The following ESCMID members have received a Research Grant in 2014 for the indicated project. Paula Espinal Microbiology, Centre Esther Koplowitz, Barcelona, Spain Project: Relationship between resistance mechanisms and potential virulence in Acinetobacter spp. strains using the Caenorhabditis elegans model Anália Lourenço University of Vigo, Ourense, Spain Project: Reconstruction of polymicrobial interactions in infections: the case of Pseudomonas aeruginosa and Candida albicans cross talk in ventilator-associated pneumonia Sandra Sousa Infection and Immunity, Group of Molecular Microbiology, IBMC, Porto, Portugal Project: Novel interfaces during host responses to pore forming toxins: crosstalk between ER chaperones and cytoskeletal proteins 14 24th ECCMID / Barcelona Final Programme Ana Sofia Ferreira BSRG, Institute for Biotechnology and Bioengineering (IBB)/Instituto Superior Técnico (IST), Lisbon, Portugal Project: How do bacterial phosphotyrosine phosphatase proteins modulate host-pathogen interactions? Michael McConnell Laboratory of Infectious Diseases, Biomedical Institute of Seville, Seville, Spain Project: Identification of novel antibiotic targets for Acinetobacter baumannii through the characterization of metabolic genes required for biofilm formation, virulence and infection Debby van Riel Viroscience, Erasmus MC, Rotterdam, The Netherlands Project: Cell-to-cell transmission of influenza viruses along the olfactory route Mateja Jelen Institute of Microbiology and Immunology, Ljubljana, Slovenia Bostjan J. Kocjan Institute of Microbiology and Immunology, Ljubljana, Slovenia Project: Profile of the protein response in the process to tetracycline resistance by Coxiella burnetii Project: Genome sequencing analysis of more than 2’000 vaccine-relevant, globally circulating, human papillomavirus HPV-6 and HPV-11 isolates Project: Determination of molecular mechanisms of low-risk HPV-mediated carcinogenesis Overview & Programme Awards Gabriela Flores-Ramirez Department of Rickettsiology, Institute of Virology, Bratislava, Slovakia ESCMID / FEMS Fellow 2014 Project: New 3D-infection models based on tissue-engineering to study pathogenicity of Helicobacter pylori and Campylobacter jejuni Isabel Soares Silva Serviço de Nefrologia, Hospital de S. João, Porto, Portugal Project: Establishment of an in vitro model system for the study of biofilm formation in haemodialysis tunneled catheters Posters Project: PLGA nanoparticles as specific carriers for nebulized drug delivery of antibiotic combinations against respiratory infections caused by high-risk clones of P. aeruginosa in the murine model Cynthia Mira Sharma Institute for Molecular Infection Biology (IMIB)/ Research Center for Infectious Diseases (ZINF), University of Würzburg, Würzburg, Germany ePosters Jana Basas Satorras Infectious Diseases, Hospital Universitari Vall d’Hebron, Barcelona, Spain Chairs, Speakers & Authors ESCMID / FEMS Fellow 2014 Project: The ATP-binding cassette transporters Plasmodium falciparum multidrug resistance proteins (pfMRPs) and their relevance in antimalarial drug resistance 24th ECCMID / Barcelona Final Programme 15 General Information Exhibition M. Isabel Veiga Life and Health Sciences Research Institute (ICVS), University of Minho, Braga, Portugal ESCMID TAE Awards for Training Achievements 2014 Neven Papic University Hospital for Infectious Diseases, Zagreb, Croatia Liliana Praticò Fondazione IRCCS Policlinico San Matteo, Pavia, Italy Infectious Diseases Infectious Diseases Erlangga Yusuf University Hospital Brussels, Brussels, Belgium Medical Microbiology ISF Sepsis Award 2014 Jacqueline Lankelma will give a short presentation about her project in the ISF session on Saturday, 10 May 2014 from 13.30 – 15.30 h in Hall K. Jacqueline M. Lankelma Academic Medical Center, Amsterdam, The Netherlands Project: Protective role of the gut microbiota in pneumoniaderived sepsis 16 24th ECCMID / Barcelona Final Programme Awards, Grants and Fellowships 2014 Travel Grant Awardees The ECCMID travel grant programme is sponsored by the European Society of Clinical Microbiology and Infectious Diseases (ESCMID). Grants were awarded to those with outstanding abstracts. Exhibition Chairs, Speakers & Authors Posters ePosters Overview & Programme Awards Lankelma, Jacqueline (Amsterdam, The Netherlands) Le Govic, Yohann (Lille, France) Leon, Ricardo (Madrid, Spain) Lopez-Cortes, Luis Eduardo (Seville, Spain) Lozano García, Lorena (Murcia, Spain) Lucas, Marjolein Jose (Amsterdam, The Netherlands) Mason, Lauren Maxine Kate (Amsterdam, The Netherlands) Mena Romo, Damián (Seville, Spain) Micaelo, Maite (Paris, France) Mika, Moana (Berne, Switzerland) Mouro Pinto, Rita (Porto, Portugal) Norihito, Kaku (Nagasaki City, Japan) Ong, David (Utrecht, The Netherlands) Ozog, Yves (Maastricht, The Netherlands) Payne, Michael (Vancouver, Canada) Pires, João (Porto, Portugal) Pulido Toledano, Marina (Seville, Spain) Radulescu, Mihaela Andreea (Bucharest, Romania) Rajendran, Ranjith (Glasgow, UK) Rascanu, Aida (Bucharest, Romania) Ribeiro Gonçalves, Teresa (Porto, Portugal) Sánchez – Valenzuela, Antonio (Madrid, Spain) Schröder, Wiebke (Tübingen, Germany) Seiffert, Salome (Berne, Switzerland) Shaw, Timothy (Belfast, UK) Simões Silva, Liliana (Porto, Portugal) Siniuk, Kanstantsin (Minsk, Belarus) Smith, Jordan (Royal Oak, MI, United States) Stappers, Mark (Nijmegen, The Netherlands) Svensson, Elin (Uppsala, Sweden) Tkhilaishvili, Tamta (Tbilisi, Georgia) van Dorp, Sofie Maria (Leiden, The Netherlands) van Mourik, Maaike S.M. (Utrecht, The Netherlands) van Vught, Lonneke Alette (Amsterdam, The Netherlands) Varlamis, Sotirios, Thessaloniki (Kalamaria, Greece) Viala, Céline (Paris, France) Vidal García, Matxalen (Zaragoza, Spain) Wagemakers, Alex (Amsterdam, The Netherlands) Wright, Laura (London, UK) Yan, Lin (Seattle, WA, United States) 24th ECCMID / Barcelona Final Programme 17 General Information Adamczuk, Marcin (Minsk Mazowiecki, Poland) Ainoda, Yusuke (Tokyo, Japan) Altinkanat Gelmez, Gulsen (Istanbul, Turkey) Amado Cecílio, Pedro (Matosinhos, Portugal) Amarsy-Guerle, Rishma (Paris, France) Baietto, Lorena (Turin, Italy) Barber, Katie (Detroit, United States) Birgand, Gabriel (Paris, France) Blanco Lobo, Pilar (Seville, Spain) Bulnes Ramos, Ángel (Seville, Spain) Candel Perez, Carmen (Murcia, Spain) Chilton, Caroline (Leeds, UK) Claeys, Kimberly (Detroit, United States) D’Abramo, Alessandra (Rome, Italy) de Jong, Hanna (Amsterdam, The Netherlands) de Stoppelaar, Sacha (Amsterdam, The Netherlands) Delaire, Caroline (Poitiers, France) Di Nauta, Alessia (Turin, Italy) Diolez, Jeremie (Pessac, France) Dudikova, Daria (Kiev, Ukraine) Dulama, Raluca Ioana (Bucharest, Romania) Fernandez-Barat, Laia (Barcelona, Spain) Foschi, Federico (Tübingen, Germany) García Quintanilla, Meritxell (Seville, Spain) Gawryszewska, Iwona (Warsaw, Poland) Gits-Muselli, Maud, (Paris, France) Gonzalez Sanz, Marta (London, UK) Gostev, Vladimir (St. Petersburg, Russian Federation) Grosso Ledo, Filipa (Porto, Portugal) Gueret, Dorothee (Paris, France) Heimann, Sebastian (Cologne, Germany) Hertz, Frederik Boetius (Hvidovre, Denmark) Holban, Alina Maria (Bucharest, Romania) Holmes, Christopher William (Leicester, UK) Huson, Michaela Aurelia Maria (Amsterdam, The Netherlands) Istrate, Claudia (Bucharest, Romania) Jacquier, Hervé (Paris, France) Johansson, Åsa (Växjö, Sweden) Kasanmoentalib, Erna Soemirien (Amsterdam, The Netherlands) Khodaparast, Laleh (Leuven, Belgium) Lakatos, Botond (Budapest, Hungary) Scientific Programme Overview Saturday, 10 May 2014 8:45 9:00 Hall A Hall B Hall C Hall D 08:45 – 12:45 P. 29 EW10: Antimicrobial susceptibility testing with EUCAST breakpoints and methods 08:45 – 10:45 P. 27 EW01: Infection prevention and management in long-term care facilities 08:45 – 10:45 P. 27 EW02: Basic concepts of pharmacokinetics and pharmacodynamics 08:45 – 10:45 P. 27 EW03: Tuberculosis and other mycobacterial infections in low-income countries Hall E 08:45 – 10:45 EW04: Vaccination in the elderly: perspectives P. 27 10:00 11:00 11:00 – 13:00 EW11: Recent research in critically ill patients: hands-on evidence P. 29 11:00 – 13:00 P. 30 11:00 – 13:00 P. 30 EW12: EW13: Bloodstream infections: opportunities Basics of infections in travellers for outcome improvement 11:00 – 13:00 P. 30 EW14: Elderly and chronic hepatitis C – to treat or not to treat? 12:00 13:00 13:30 – 15:30 What’s new in sepsis in 2014 14:00 P. 32 13:30 – 15:30 Integrated Symposium (not included in main event CME/CPD credit) Refer to page 316 for details 13:30 – 15:30 Integrated Symposium (not included in main event CME/CPD credit) Refer to page 316 for details 13:30 – 15:30 Uncertainties in transplant vaccination 16:30 – 18:30 P. 35 The Good, the Bad and the Ugly: recently approved and developmental anti-bacterials 16:30 – 18:30 P. 35 New insights in epidemiology, resistance and pathogenesis to improve HIV management P. 32 13:30 – 15:30 P. 32 Lessons learned from Clostridium difficile molecular epidemiology 15:00 16:00 17:00 16:30 – 18:30 P. 34 Implementing international guidelines to reduce the spread of MDR Gram-negatives at national level 16:30 – 18:30 Integrated Symposium (not included in main event CME/CPD credit) Refer to page 317 for details 16:30 – 18:30 Integrated Symposium (not included in main event CME/CPD credit) Refer to page 317 for details 18:00 19:00 19:00 – 22:00 Opening Ceremony followed by Networking Reception Sunday, 11 May 2014 Hall A Hall B 7:45 8:00 07:45 – 08:45 Sepsis management beyond antibiotics 9:00 09:00 – 11:00 P. 39 09:00 – 11:00 What is new on surgical site infection Integrated Symposium prevention? (not included in main event CME/CPD credit) Refer to page 319 for details 10:00 Hall C Hall D Hall E 07:45 – 08:45: Outbreak of P. 39 P. aeruginosa in your hospital and you think it could be water-related? Want to know what to do next? P. 39 09:00 – 11:00 Integrated Symposium (not included in main event CME/CPD credit) Refer to page 319 for details 09:00 – 11:00 Monitoring antibiotic use P. 40 09:00 – 11:00 Integrated Symposium (not included in main event CME/CPD credit) Refer to page 320 for details 11:00 12:00 13:00 11:30 – 12:30 P. 42 11:30 – 12:30 P. 43 11:30 – 12:30 P. 43 11:30 – 12:30 P. 43 11:30 – 12:30 P. 43 Deep insights in mycobacteria: Genomic diagnostics: transforming Macrolides are still safe and effective Great scientific success with scarce Emergence of Clostridium difficile genomics and susceptibility clinical and public health microbiology to be used in clinical practice. Pro / resources. Is money issue a crucial infections outside healthcare facilities practice Con debate point? 13:00 – 14:00: EPOSTER & POSTER VIEWING 13:00 – 14:00 P. 77 ePoster Session: Post-surgical and implant infections: from head to knee 14:00 14:30 – 15:30 The year in Infection Control 15:00 16:00 17:00 P. 45 14:30 – 15:30 Hepatitis B treatment and management 16:00 – 18:00 P. 48 16:00 – 18:00 Improving empirical antibiotic treat- Integrated Symposium ment in hospital (not included in main event CME/CPD credit) Refer to page 321 for details 18:00 18 24th ECCMID / Barcelona Final Programme P. 46 14:30 – 15:30 P. 46 Knowledge and social norms shaping the discovery, use, and resistance trends of antimicrobial agents 16:00 – 18:00 Integrated Symposium (not included in main event CME/CPD credit) Refer to page 321 for details 14:30 – 15:30 P. 46 14:30 – 15:30 Training in infection in Listeria and listeriosis Europe – progress in curricula and assessments P. 46 16:00 – 18:00 P. 48 16:00 – 18:00 P. 49 Use of next generation sequencing in Making sense of our relationships clinical practice with mucosal commensals and pathogens Meet-the-Expert Sessions 2-hour Symposia 1-hour Symposia Hall F 08:45 – 10:45 EW05: Tick-borne diseases prevalent in Europe Keynote Lectures Hall G 1-hour Oral Sessions 2-hour Oral Sessions ePoster & Poster Sessions Hall H P. 28 08:45 – 10:45 P. 28 08:45 – 10:45 P. 28 EW06: EW07: Diagnosis and treatment of Viral infections in pregnancy Helicobacter pylori infection. What is new in 2014? Integrated Symposia Saturday, 10 May 2014 Hall I Hall J 08:45 – 10:45 P. 28 EW08: Management of ocular parasitic diseases 08:45 – 10:45 P. 29 EW09: How to diagnose and treat bacterial and fungal biofilm infections Registration, Exhibition, Posters Hall 132/133 Registration 07:00 – 18:30 Exhibition 12:00 – 18:45 Posters 15:30 – 16:30 Session I P. 33 13:30 – 15:30 Integrated Symposium (not included in main event CME/CPD credit) Refer to page 316 for details 16:30 – 18:30 P. 36 16:30 – 18:30 Epidemiology based on Integrated Symposium whole genome sequencing (not included in main event CME/CPD credit) Refer to page 317 for details 16:30 – 18:30 P. 36 Laboratory response to emerging viral diseases: from pathogen discovery to disease monitoring 11:00 – 13:00 P. 31 EW18: Human parasites of the gut: epidemiology and diagnostic approaches in the molecular era 11:00 – 13:00 P. 31 EW19: ESCMID guidelines for diagnosis and treatment of Aspergillus diseases 13:30 – 15:30 P. 34 Application of new methods in medical microbiology and infection control 13:30 – 15:30 Integrated Symposium (not included in main event CME/CPD credit) Refer to page 316 for details 16:30 – 18:30 Integrated Symposium (not included in main event CME/CPD credit) Refer to page 318 for details 16:30 – 18:30 Carbapenemases from prevention to treatment ePosters Viewing Throughout congress hours 13:30 – 16:45 TAE Trainees Day P. 34 P. 37 Overview & Programme P. 33 13:30 – 15:30 Improving antibiotic prescription quality 11:00 – 13:00 P. 31 EW17: How to prevent the consequences of EBV infection in transplant recipients? Sunday, 11 May 2014 Hall G 07:45 – 08:45 P. 39 Addressing the problem of MDR Neisseria gonorrhoeae 11:30 – 12:30 Automation in diagnostic bacteriology 13:00 – 14:00 ePoster Session: PK/PD to imporve treatment of critically ill patients Registration, Exhibition, Posters Hall J 07:45 – 08:45 P. 39 Controversies in treatment of malaria and crimean-congo haemorrhagic fever P. 44 11:30 – 12:30 MDR Acinetobacter baumannii 07:45 – 08:45 P. 39 07:45 – 08:45 P. 39 Registration Screening for carbapenemase New viruses: pathogens or innocent 07:00 – 18:00 production, molecular and phenotypic bystanders? methods Exhibition 09:00 – 17:30 09:00 – 11:00 P. 41 09:00 – 11:00 P. 41 09:00 – 11:00 P. 42 Posters News in travel, tropical and parasitic MALDI-TOF mass spectrometry: Basic science: pathogenesis and 12:30 – 13:30 Session II infections ongoing revolution in clinical epidemiology of Gram-positive 13:30 – 14:30 Session III microbiology bacteria Posters P. 40 09:00 – 11:00 Integrated Symposium (not included in main event CME/CPD credit) Refer to page 320 for details ePosters Viewing Throughout congress hours P. 44 11:30 – 12:30 P. 44 11:30 – 12:30 The great filter: parasitic infections Emerging resistance in fungi of the liver P. 45 11:30 – 12:30 P. 45 Viral opportunists in the critically ill patient 13:00 – 14:00: EPOSTER & POSTER VIEWING P. 79 13:00 – 14:00 P. 77 13:00 – 14:00 P. 78 13:00 – 14:00 P. 79 ePoster Session: ePoster Session: ePoster Session: Microbiome and resistance: what are STD and other genital infections Antifungal drug susceptibility and they telling us? resistance 14:30 – 15:300 P. 46 14:30 – 15:30 Why are some carbapenemases Microbiome and microbiota: successful? new “M”s in microbiology 16:00 – 18:00 Integrated Symposium (not included in main event CME/CPD credit) Refer to page 322 for details Hall I 16:00 – 18:00 Integrated Symposium (not included in main event CME/CPD credit) Refer to page 322 for details P. 47 14:30 – 15:30 An update on malaria P. 47 14:30 – 15:30 P. 48 14:30 – 15:30 Different prevention strategies in Hot topic: Ebola in Africa immunocompromised patients P. 48 Exhibition 09:00 – 11:00 Exploring and treating biofilms Hall H Chairs, Speakers & Authors Hall F ePosters 13:30 – 15:30 Ticks and tick-borne pathogens 11:00 – 13:00 P. 31 EW16: Update on anaerobes: new methods bring new information about the bugs and their importance in health and disease 16:00 – 18:000 P. 50 16:00 – 18:000 P. 50 16:00 – 18:000 P. 50 Ins and outs of Legionnaires disease Infections and devices: imaging & Bacterial persistence and tolerance: nuclear medicine meets infectious from bench to bedside diseases 24th ECCMID / Barcelona Final Programme 19 General Information 11:00 – 13:00 P. 30 EW15: When is a food-borne infection not a food-borne infection? Scientific Programme Overview Monday, 12 May 2014 HALL A HALL B HALL C 7:45 07:45 – 08:45 P. 51 8:00 The management of HIV/HCV infection in the era of direct active drugs 9:00 09:00 – 11:00 What is hot in HIV in 2014? 10:00 HALL D HALL E 07:45 – 08:45 P. 51 EUCAST questions and answers P. 51 09:00 – 11:00 Integrated Symposium (not included in main event CME/CPD credit) Refer to page 323 for details 09:00 – 11:00 Integrated Symposium (not included in main event CME/CPD credit) Refer to page 323 for details 09:00 – 11:00 Colistin: position in the era of multi-resistance P. 52 09:00 – 11:00 Integrated Symposium (not included in main event CME/CPD credit) Refer to page 324 for details 11:00 11:30 – 12:30 P. 53 11:30 – 12:30 P. 53 11:30 – 12:30 P. 54 11:30 – 12:30 Better to prevent than to cure: case Molecular diagnosis: commercial or Fighting against fungal infections: Antivirulence drugs of HIV home-made tests – Pro / Con debate cells on the front lines 12:00 P. 54 11:30 – 12:30 Enterococcal resistance P. 54 13:00 – 14:00: ePoster & Poster viewing 13:00 13:00 – 14:00 P. 81 ePoster Session: Antibacterial drug activity and interactions in Gram-positive organisms 14:00 14:30 – 15:30 HIV – behaviour and beliefs 15:00 P. 56 14:30 – 15:30 P. 56 14:30 – 15:30 P. 57 14:30 – 15:30 P. 57 14:30 – 15:30 Going away from blood: why not to Excellence Award Lecture: Close New antibiotics in clinical trials T-cells in invasive aspergillosis test oral fluid and urine? encounters of the third kind – pathogens and globalisation 16:00 16:00 – 18:00 P. 59 Cryptococcal infections in HIVinfected patients: what is new in 2014? 17:00 16:00 – 18:00 Integrated Symposium (not included in main event CME/CPD credit) Refer to page 325 for details 16:00 – 18:00 Integrated Symposium (not included in main event CME/CPD credit) Refer to page 325 for details 16:00 – 18:00 P. 59 16:00 – 18:00 New transmission routes and Predicting the future in fungal genotypic diversity: are we looking at diagnosis and therapy a new MRSA? P. 57 P. 60 18:00 Tuesday, 13 May 2014 Hall A Hall B 7:45 8:00 9:00 07:45 – 08:45 How to use next generation sequencing in future virology 09:00 – 11:00 Clinical Grand Round 2014 Hall C Hall D Hall E P. 63 07:45 – 08:45 P. 63 07:45 – 08:45 P. 63 Control of vancomycin-resistant Management and troubleshooting of enterococci: efforts justified? in-house molecular diagnostics in the microbiological lab 07:45 – 08:45 P. 63 Antimicrobial resistance research, supported by funding from the EU and the US NIH/NIAID P. 64 09:00 – 11:00 P. 64 09:00 – 11:00 P. 64 09:00 – 11:00 P. 65 09:00 – 11:00 P. 65 The challenge of respiratory viruses What is new in immunocompromised Nebulised antibiotics: challenge Combined antimicrobial therapy patients? for 2014 for multi-resistant Gram-negative bacteria 10:00 11:00 12:00 11:30 – 12:30 P. 67 11:30 – 12:30 P. 67 11:30 – 12:30 P. 68 11:30 – 12:30 P. 68 11:30 – 12:30 P. 69 The year in Clinical Microbiology Cross-neutralising antibodies for Surveillance of healthcare-associated Advances in CMV infection in transYoung Investigator Award Lectures respiratory virus therapy and vaccine infections: infections or procedures? plant recipients design ePoster & Poster Viewing 13:00 14:00 13:30 – 15:30 P. 70 13:30 – 15:30 Controlling transmission of multidrug- Hot topics in resistant pathogens in the intensive vaccine-preventable diseases care unit 15:00 15:15 15:30 20 24th ECCMID / Barcelona Final Programme P. 70 13:30 – 15:30 P. 70 13:30 – 15:30 Antimicrobial prophylaxis of surgical Emerging infectious diseases site infections: time to review? P. 71 13:30 – 15:30 Case-based decisions in the era of XDR Gram-negatives: towards individualised therapy? P. 71 Meet-the-Expert Sessions 2-hour Symposia 1-hour Symposia HALL F Keynote Lectures HALL G 1-hour Oral Sessions 2-hour Oral Sessions ePoster & Poster Sessions HALL H Integrated Symposia Monday, 12 May 2014 HALL I 07:45 – 08:45 New nomenclature: new species – any meaning for clinical relevance? P. 51 07:45 – 08:45 Altered drug disposition in the elderly 09:00 – 11:00 Full laboratory automation P. 52 09:00 – 11:00 Integrated Symposium (not included in main event CME/CPD credit) Refer to page 324 for details 09:00 – 11:00 P. 52 09:00 – 11:00 Outbreaks of MDR Gram-negative An update on leishmaniasis bacteria: what works and what does not work? Registration, Exhibition, Posters HALL J 07:45 – 08:45: P. 51 Registration Current challenges and emerging evidence 07:00 – 18:00 of infection control and prevention Exhibition measures in long-term care facilities 09:00 – 17:30 P. 53 09:00 – 11:00 P. 53 Posters Staphylococcus aureus 12:30 – 13:30 Session IV bacteraemia: controversial issues 13:30 – 14:30 Session V P. 51 07:45 – 08:45 P. 51 Who should and who should not receive drug treatment for Chagas disease? ePosters Viewing Throughout congress hours 11:30 – 12:30 P. 55 11:30 – 12:30 P. 55 11:30 – 12:30 Molecular detection of resistance: Community-acquired pneumonia – Viral paediatric infections dream or reality? current challenges and future directions P. 55 11:30 – 12:30 P. 56 11:30 – 12:30 P. 56 Acute anaemia after treatment of The year in Infectious Diseases malaria with intravenous artesunate – a new variant of “blackwater fever”? 13:00 – 14:00: ePoster & Poster viewing 13:00 – 14:00 P. 82 13:00 – 14:00 P. 83 13:00 – 14:00 P. 84 13:00 – 14:00 P. 85 ePoster Session: ePoster Session: ePoster Session: ePoster Session: Assessing and decreasing environCommunity-acquired pneumonia Vaccine development Highlights from molecular mycology mental contamination P. 58 14:30 – 15:30 P. 58 14:30 – 15:30 P. 58 Diagnostic tools in parasitology On the cutting edge of infection control research: what to do when evidence is missing? 16:00 – 18:00 P. 60 16:00 – 18:00 P. 60 Forensic and post-mortem New approaches to prevent microbiology in the 21st century transmission of Clostridium difficile infections 16:00 – 18:00 P. 60 Non-molecular diagnosis of central nervous system and bloodstream infections Overview & Programme 16:00 – 18:00 Integrated Symposium (not included in main event CME/CPD credit) Refer to page 326 for details P. 57 14:30 – 15:30 Viral diagnostics in the immunocompromised 16:00 – 18:00 Integrated Symposium (not included in main event CME/CPD credit) Refer to page 326 for details Tuesday, 13 May 2014 Hall F Hall G Hall H 07:45 – 08:45 P. 63 07:45 – 08:45 P. 63 Strategies for malaria prevention, why Healthcare providers and influenza do national guidelines differ? vaccination Hall I Registration, Exhibition, Posters Hall J 07:45 – 08:45 P. 63 How to treat MDR tuberculosis? ePosters 14:30 – 15:30 P. 57 14:30 – 15:30 The effects of antibiotic pollution on Detection of broad-spectrum the environmental resistance gene beta-lactamases reservoir Registration 07:00 – 15:30 Exhibition 09:00 – 15:30 Posters P. 67 09:00 – 11:00 P. 67 Optimisation of empirical and targeted Posters 12:30 – 13:30 Session VI antifungal therapy for invasive aspergillosis ePosters Viewing Throughout congress hours Chairs, Speakers & Authors 11:30 – 12:30 P. 69 Advances in molecular mycology: notes from the bench P. 66 09:00 – 11:00 P. 67 09:00 – 11:00 PK/PD – the merits of models and The hidden Beijing measurement M. tuberculosis pandemic 11:30 – 12:30 P. 69 11:30 – 12:30 P. 69 11:30 – 12:30 P. 69 Can we treat Gram-negative Mycobacteria in cutaneous infections HIV and hepatitis C co-infection: bacteraemia with a short-course of double trouble? antibiotics? Pro / Con debate ePoster & Poster Viewing P. 72 13:30 – 15:30 New old antibiotics: safety and efficacy P. 73 13:30 – 15:30 Improving treatment of severe infections P. 74 13:30 – 15:30 P. 74 13:30 – 15:30 P. 75 Two-faced companions: highlights in PCR and other molecular tests the world of anaerobes directly on blood: what is new? Exhibition 13:30 – 15:30 Clinical mycology update 2014 24th ECCMID / Barcelona Final Programme 21 General Information 09:00 – 11:00 P. 65 09:00 – 11:00 Healthcare-associated infections – Bacterial paediatric infections from analysis to interventions Sat, 10 May 2014 24th ECCMID 2014, Barcelona, Spain Don’t miss the 4th TAE Trainees Day session! If you are currently training in Clinical Microbiology or Infectious Diseases, this is an excellent opportunity to receive valuable information and tips from internationally renowned experts as well as to network with trainees from all over Europe. This year’s programme will cover STDs, bioterrorism and outbreak detection, and sepsis in a CM and ID perspective. E! VISIT TA WorlD SCMID In THE E ID BArCElonA AT ECCM Sat, 10 May 2014, 13:30 – 16:45, Room 133/134 Chairs: P. Maver Vodicar, Ljubljana, Sl E. Vlieghe, Antwerp, BE Welcome and TAE President’s address P. Maver Vodicar, Ljubljana, Sl STDs – are they still hot? Beyond the typical case M. Vera Garcia, Madrid, ES The silent threat of bioterrorism – be prepared M. Barbeschi, Geneva, CH The challenges of outbreak detection and response K. Leitmeyer, Stockholm, SE Sepsis: think globally, treat locally – CM perspective S. Stefani, Catania, IT Sepsis: think globally, treat locally – ID perspective E. Vlieghe, Antwerp, BE Also prepared in collaboration with TAE: Sat 10 May 2014, 11:00 – 13.00, Hall G: Update on anaerobes: new methods bring new information about the bugs and their importance in health and disease Sun 11 May 2014, 11:30 – 12:30, Hall D: Great scientific success with scarce resources. Is money issue a crucial point? Sun 11 May 2014, 14:30 – 15:30, Hall D: Training in infection in Europe – progress in curricula and assessments 22 24th ECCMID / Barcelona Final Programme www.eccmid.org www.escmid.org/tae [email protected] www.facebook.com/ESCMID.TAE TAE – Trainee Association of ESCMID CME Accreditation • • Target Audience ECCMID 2014 is the global meeting place for microbiologists, infectious disease specialists and related fields. Because of the diverse, clinically focused educational offering, participants are able to tailor the curriculum to meet the needs of international clinicians of all levels of experience. Accreditation Statement and Credit Designation European Accreditation Council for Continuing Medical Education (UEMS/EACCME) The 24th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) is accredited by the European Accreditation Council for Continuing Medical Education (EACCME) to provide the following CME activity for medical specialists. The EACCME is an institution of the European Union of Medical Specialists (UEMS): www.uems.net The 24th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) is designated for a maximum of, or up to, 23 European external CME credits. Each medical specialist should claim only those hours of credit that he/she actually spent in the educational activity. American Medical Association (AMA) Through an agreement between the European Union of Medical Specialists and the American Medical Association, physicians may convert EACCME credits to an equivalent number of AMA PRA Category 1 Credits™. Information on the process to convert EACCME credit to AMA credit can be found at www.ama-assn.org/go/internationalcme Royal College of Physicians and Surgeons of Canada Live educational activities, occurring outside of Canada, recognised by the UEMS-EACCME for ECMEC credits are deemed to be Accredited Group Learning Activities (Section 1) as defined by the Maintenance of Certification Program of The Royal College of Physicians and Surgeons of Canada. For more information visit: www.royalcollege.ca 6 Sunday, 11 May 2014 6 Monday, 12 May 2014 6 Tuesday, 13 May 2014 5 Total Credits: 23 To Receive Your CME/CPD Certificate Your CME/CPD certificate will be delivered electronically after completing the educational evaluation and credit claiming procedure. The process will take 5 minutes. We thank you for your feedback as it is an important part of the CME/CPD accreditation process and helps improve future educational offerings. Before 10 June 2014: 1. Follow the link in the email notification sent at the end of the event or visit the CME/CPD Accreditation page on the event website. 2. Complete the anonymous online evaluation. 3. You will be automatically directed to the credit claim system. 4. Login with your unique User ID (included in your registration package, on your badge or in the email sent after the event). 5. Indicate the number of hours you attended. 6. Your CME/CPD certificate will be available for download and also emailed to the address provided. 7. Retain the certificate for your personal records. Disclosure and Resolution of Personal Conflicts of Interest In accordance with CME/CPD accreditation criteria and standards for commercial support to ensure balance, independence, objectivity, and scientific rigor, those in control of the educational content must disclose potential or actual conflicts of interest. Disclosure information is evaluated and conflicts of interest resolved. Disclosure is made to participants prior to the activity. Participants will be asked on the evaluation to assess the objectivity and independence of the event. Disclosure information can be viewed on the congress website under the CME information pages. Industry Support Disclosure This event is supported, in part, by funding from industry. All support is managed in strict accordance with CME/CPD accreditation criteria and standards for commercial support. Appropriate acknowledgement of all supporting organisations is made in the programme guide, on the event website, and with signage during the event. • • A list of all industry supporters is available on page 3 Detailed programmes for all Industry Sessions are available on pages 314–326 24th ECCMID / Barcelona Final Programme 23 Overview & Programme • Saturday, 10 May 2014 ePosters • Maximum Credits Posters • Day Chairs, Speakers & Authors • Address individual needs in compliance with their Continuous Professional Development (CPD) plan Exchange ideas and knowledge in the field of microbiology and infectious disease across continents, institutions and individuals Discuss the latest research outcomes in the field of antimicrobials, molecular biology, virology and infection control Discuss the latest research outcomes in the field of infectious diseases, microbiology and research Discuss outcomes of the latest studies in Europe in the field of public health and vaccines Summarise good and bad immune responses Discuss diagnostics, therapeutics and prevention in the field of infectious diseases Exhibition • Credit Breakdown Each participant should claim only those hours of credit that he/ she actually spent in the educational activity. General Information Educational Objectives After attending this event, participants should be able to: Introduction to the Scientific Programme Educational Workshops At the beginning of ECCMID, on Saturday morning, 10 May 2014, from 08:45 – 13:00 a series of Educational Workshops will take place. They are organised in cooperation with ESCMID Study Groups and partnering organisations. Participation in Educational Workshops is free of charge and corresponding educational material is available online in the ESCMID Online Lecture Library (www.escmid.org/oll). ePoster Sessions Selected ePosters have been scheduled for ePoster sessions on Sunday, 11 May and Monday, 12 May between 13:00 – 14:00. In additional to being displayed on the ePoster stations though the 4 congress days, these selected ePosters will be presented orally in the designated session halls. Please refer to the scientific programme for the detailed ePoster sessions (see page 313). The presenting author is indicated by an asterisk (*). Meet-the-Expert Sessions Sunday through Tuesday, the day will start at 07:45 with Meetthe-Expert Sessions led by experts in their fields. These sessions depend on active participation of the audience. After a short presentation, the expert will open the session for discussion. Coffee will be offered. ePoster Viewing ePosters have been divided in 38 thematical sessions, which will be displayed all 4 congress days on 25 ePoster stations within the CCIB, on the mobile website and application of the congress. The new ePoster format will give participants the possibility to interact with presenters and send the ePoster by email (see page 87). The presenting author is indicated by an asterisk (*). TAE Trainees Day On Saturday, 10 May 2014, 13:30 – 16:45, the Trainee Association of ESCMID (TAE) organises the European Trainees Day, a day of teaching dedicated to the unique needs of trainees. During this session various topics in CM and ID will be discussed in a highly interactive way between trainees and experienced CM and ID specialists. A second and equally important aim of the day is to give trainees an opportunity to meet and network with each other. Participation is free of charge to ECCMID attendees. Keynote and Award Lectures Sunday through Tuesday at 11:30 and 14:30, lectures of 60 minutes will be given by opinion leaders in their fields as well as by the winner of the ESCMID Excellence Award 2014. Symposia From 09:00 – 12:30 and from 14:30 – 18:00 each day, parallel symposia will convene renowned speakers from Europe and other continents who will cover a wide range of recent developments in their fields. On Tuesday, 13 May 2014, the last round of symposia takes place from 13:30 – 15:30. A number of symposia are arranged in cooperation with ESCMID Study Groups, while others are jointly organised with partnering societies or organisations. Symposia arranged by the industry are organised in close cooperation with the ECCMID Programme Committee. They are an integral part of the scientific programme (Integrated Symposia). Oral Sessions During the same time slots as the before mentioned symposia, you will also find sessions composed of abstracts selected for oral presentation, which are indicated by the prefix “O” in front of the programme numbers. The presenting author is indicated with an asterisk (*). 24 24th ECCMID / Barcelona Final Programme Poster Sessions Most of the accepted abstracts are scheduled for poster presentation from Saturday through Tuesday. The selection is based on a blind review by at least three experts in each field. The posters are displayed in the Poster Area on the 2nd floor of the CCIB. The poster area is open to all participants on Saturday from 12:00 –18:30, on Sunday and Monday from 09:00 – 17:30 and on Tuesday from 09:00 – 15:00. Please note that posters are exchanged on a daily basis. Poster authors must be present at their posters for discussion during their poster session (see page 313 for details). The presenting author is indicated by an asterisk (*). Publication Only Due to a large response to the call for abstracts, the Programme Committee has had to restrict the number of abstracts for presentation during the meeting. Abstracts of this category are not included in the Final Programme but are published in the ESCMID Online Lecture Library (www.escmid.org/oll). Online Meeting Planner during the 24th ECCMID The final scientific programme including all accepted abstracts is available on the congress website at www.eccmid.org. Go to the “Scientific Programme” link to compose your personalised programme of lectures. You can use the search function to find keywords, speakers and chairpersons. In addition all functions have been implemented in the mobile application and mobile website onsite as well. The following prefixes have been used throughout the programme: EW = Educational Workshop O = Oral Session KL = Keynote Lecture eP = ePoster Session SY = Symposium P = Poster Session ME = Meet-the-Expert Session IS = Integrated Symposium ESCMID Business Meetings Saturday, 10 May 2014 13:00 – 14:00 17:00 – 18:45 Monday, 12 May 2014 CMI & NMNI Reception Room 124/125 Reception for travel grantees, Young Investigators and Excellence Awardee Room 124/125 24th ECCMID / Barcelona Final Programme 25 General Information Exhibition Chairs, Speakers & Authors Posters ePosters Overview & Programme 09:00 – 12:00 CAESAR Meeting Room 122/123 12:45 – 14:15 EUCAST General Committee Meeting Room 122/123 13:15 – 14:15 ESGAI Business Meeting Room M211/M212 13:15 – 14:15 ESGAP Business Meeting Sunday, 11 May 2014 Room 132 13:15 – 14:15 ESGB Business Meeting 13:15 – 14:15 ESGARS Business Meeting Room 131 Room 132 13:15 – 14:15 ESGBIS Business Meeting 13:15 – 14:15 ESGCP Business Meeting Room 125 Room 133/134 13:15 – 14:15 ESGBOR Business Meeting 13:15 – 14:15 ESGICH Business Meeting Room 133/134 Room M213/M214 13:15 – 14:15 ESGCIP Business Meeting 13:15 – 14:15 ESGMD Business Meeting Room 130 Room 124 13:15 – 14:15 ESGEM Business Meeting 13:15 – 14:15 ESGNI Business Meeting Room 129 Room 131 13:15 – 14:15 ESGIB Business Meeting 13:15 – 14:15 ESGVH Business Meeting Room 127/128 Room 130 13:15 – 14:15 EVASG Business Meeting 18:15 – 19:15 EFISG Business Meeting Room 124 Room 127/128 14:15 – 15:15 ESGAI: ENRIA Meeting 18:15 – 19:15 EFWISG Business Meeting Room M211/M212 Room 132 16:30 – 18:00 EUCAST AFST General Committee Meeting 18:15 – 19:15 EPASG Business Meeting Room 122/123 Room 131 18:00 – 18:30 European Council Meeting 18:15 – 19:15 ESCAR Business Meeting Room 124/125 Room 130 18:30 – 20:00 ESCMID General Assembly 18:15 – 19:45 ESGCD Business Meeting Room 133/134 Room M211/M212 18:15 – 19:15 ESGIAI Business Meeting Room 133/134 18:15 – 19:15 ESGIE Business Meeting Room 129 18:15 – 19:15 ESGITM Business Meeting Room 125 18:15 – 19:15 ESGMI Business Meeting Room 121 18:15 – 19:15 ESGMYC Business Meeting Room 124 18:15 – 19:15 ESGS Business Meeting Room 123 www.escmid.org/summerschool Summer School 13th ESCMID Summer School Sigtuna, Sweden 5 – 12 July 2014 Postgraduate and continuing medical education in clinical microbiology and infectious diseases Including: • State-of-the-art lectures • Update lectures • Small group tutorial sessions • Pro and Contra sessions • Career advice Please register at www.escmid.org/summerschool. Places are limited, apply by 9 May 2014! Organised by the ESCMID Education Subcommittee Hosted at «Sigtuna Folkhögskola» in Sigtuna, Sweden Scientific Programme Saturday, 10 May 2014 HALL B EDUCATIONAL WORKSHOP 01: Infection prevention and management in long-term care facilities 8:45 – 10:45 EDUCATIONAL WORKSHOP 03: Tuberculosis and other mycobacterial infections in low-income countries ESGAP,ESGIE,ESGNI ESGMYC Chairs: Sheldon Stone (United Kingdom) Leonardo Pagani (Switzerland) Chairs: Julian Gonzalez-Martin (Spain) Miguel Viveiros (Portugal) EW001 8:45 Antibiotic-resistant bacteria in elderly facilities: EW009 8:45 How to diagnose mycobacterial infections good news and pitfalls Richard Aschbacher (Italy) in low-income countries Miguel Viveiros (Portugal) EW011 9:45 Mycobacterial infections in HIV-positive patients in low-income countries Miguel Santin (Spain) Mical Paul (Israel) EW004 10:15 Challenges, strategies and research priorities of antimicrobial stewardship programmes in LTCFs for the elderly Dilip Nathwani (United Kingdom) arranged with the ESCMID Study Group for Antibiotic Policies (ESGAP); the ESCMID Study Group for Infections in the Elderly (ESGIE) and the ESCMID Study Group for Nosocomial Infections (ESGNI) EW012 10:15 Leprosy and Buruli ulcer in Africa Overview & Programme EW003 9:45 Clostridium difficile infection in the elderly in migrants Jon S. Friedland (United Kingdom) Emmanuelle Cambau (France) arranged with the ESCMID Study Group for Mycobacterial Infections (ESGMYC) 8:45 – 10:45 HALL E EDUCATIONAL WORKSHOP 04: Vaccination in the elderly: perspectives ePosters long-term care facilities: should infection control limit daily activities? M. Adriana Cataldo (Italy) EW010 9:15 Strategy for TB treatment and management ESGIE, EVASG Chairs: Gaetan Gavazzi (France) Susanna Esposito (Italy) HALL C EW013 8:45 Immune senescence: impact on vaccination efficacy Pierre O. Lang (Switzerland) EPASG Chairs: Johan W. Mouton (The Netherlands) Ursula Theuretzbacher (Austria) EW005 8:45 Basic concepts of PK/PD Johan W. Mouton (The Netherlands) EW014 9:15 New and old vaccines for the elderly Albert D.M.E. Osterhaus (The Netherlands) EW015 9:45 Vaccination in elderly: the need of a life-course programme Jean-Pierre Michel (Switzerland) EW006 9:15 Translating PK/PD concepts into dosing strategies William A. Craig (United States) EW016 10:15 Vaccine coverage in elderly population in Europe Piotr Kramarz (Sweden) EW007 9:45 Optimising therapy in obese and frail patients Hartmut Derendorf (United States) EW008 10:15 Optimising therapy to minimise emergence of resistance Ursula Theuretzbacher (Austria) Posters EDUCATIONAL WORKSHOP 02: Basic concepts of pharmacokinetics and pharmacodynamics arranged with the ESCMID Study Group for Infections in the Elderly (ESGIE) and with the ESCMID Vaccine Study Group (EVASG) Exhibition 8:45 – 10:45 arranged with the ESCMID PK/PD of AntiInfectives Study Group (EPASG) 24th ECCMID / Barcelona Final Programme Chairs, Speakers & Authors EW002 9:15 Implications of MDR control in different types of HALL D 27 General Information 8:45 – 10:45 Scientific Programme Saturday, 10 May 2014 8:45 – 10:45 HALL F EDUCATIONAL WORKSHOP 05: Tick-borne diseases prevalent in Europe 8:45 – 10:45 EDUCATIONAL WORKSHOP 07: Viral infections in pregnancy ESCAR, ESGBOR ESGVH Chairs: Gerold Stanek (Austria) Amel Letaief (Tunisia) Chairs: Resat Ozaras (Turkey) Dominique Salmon-Ceron (France) EW017 8:45 Human granulocytic anaplasmosis in Europe EW025 8:45 Hepatitis B in pregnancy Tatjana Avsic Zupanc (Slovenia) Resat Ozaras (Turkey) EW018 9:15 Human babesiosis in Europe EW026 9:15 Hepatitis C in pregnancy Jeremy Gray (Ireland) Philippe Sogni (France) EW019 9:45 Tick-borne encephalitis: what doctors need to know about this disease Franc Strle (Slovenia) within the sway of antibiotic maximalism Wolfgang Kristoferitsch (Austria) EW028 10:15 Hepatitis E in pregnancy Sabela Lens (Spain) arranged with the ESCMID Study Group for Coxiella, Anaplasma, Rickettsia and Bartonella (ESCAR) and with the ESCMID Study Group for Lyme Borreliosis (ESGBOR) 8:45 – 10:45 EW027 9:45 Prevention of mother to child transmission of HIV TBD EW020 10:15 Treatment regimens for Lyme neuroborreliosis HALL H HALL G EDUCATIONAL WORKSHOP 06: Diagnosis and treatment of Helicobacter pylori infection. What is new in 2014? arranged with the ESCMID Study Group for Viral Hepatitis (ESGVH) 8:45 – 10:45 HALL I EDUCATIONAL WORKSHOP 08: Management of ocular parasitic diseases ESGCP Chairs: Birgitta Evengard (Sweden) Carmen-Michaela Cretu (Romania) EW029 8:45 Ocular acanthamoebiasis EHSG Chairs: Leif P. Andersen (Denmark) Emilie Bessede (France) EW021 8:45 Real-time PCR for H. pylori diagnosis. Better than culture? Leif P. Andersen (Denmark) EW022 9:15 MALDI-TOF mass spectrometry applied to H. pylori diagnosis and typing Emilie Bessede (France) EW023 9:45 Lessons from the study of gastric microbiota Lars Engstrand (Sweden) EW024 10:15 Sequential therapy or pylera(R) to eradicate H. pylori Xavier Calvet (Spain) 28 arranged with the European Helicobacter Study Group (EHSG) 24th ECCMID / Barcelona Final Programme Francisco Arnalich (Spain) EW030 9:15 Ocular larva migrans, cysticercosis, dirofilariasis Carmen-Michaela Cretu (Romania) EW031 9:45 Ocular toxoplasmosis Hélène Yera (France) EW032 10:15 Diagnosis of ocular parasites Peter Chiodini (United Kingdom) arranged with the ESCMID Study Group for Clinical Parasitology (ESGCP) Scientific Programme Saturday, 10 May 2014 HALL J EW043 11:15 Susceptibility testing systems – are some more equal than others? John D. Turnidge (Australia) EDUCATIONAL WORKSHOP 09: How to diagnose and treat bacterial and fungal biofilm infections EW044 11:35 Issues in testing susceptibility to beta-lactam / beta-lactamase inhibitor combinations Robin Howe (United Kingdom) ESGB Chairs: Cornelia Lass-Flörl (Austria) Thomas Bjarnsholt (Denmark) EW045 11:55 Susceptibility testing of infrequently isolated EW033 8:45 Fungal biofilm diagnosis fastidious organisms Luis Martinez-Martinez (Spain) Gordon Ramage (United Kingdom) EW034 9:15 Fungal biofilm treatment EW046 12:15 Moderated panel discussion on questions from the audience (part 2) Alasdair P. MacGowan (United Kingdom) EW035 9:45 Bacterial biofilm diagnosis Thomas Bjarnsholt (Denmark) EW036 10:15 Bacterial biofilm treatment Claus Moser (Denmark) arranged with the European Committee on Antimicrobial Susceptibility Testing (EUCAST) 11:00 – 13:00 arranged with the ESCMID Study Group for Biofilms (ESGB) HALL B Overview & Programme Mariana Henriques (Portugal) EDUCATIONAL WORKSHOP 11: Recent research in critically ill patients: hands-on evidence ESGCIP Chairs: Jordi Rello (Spain) Garyfallia Poulakou (Greece) HALL A EW047 11:00 Advances in randomised control trials on candidaemia Matteo Bassetti (Italy) EUCAST Chairs: Rafael Canton Moreno (Spain) Derek F.J. Brown (United Kingdom) EW048 11:30 How molecular biology is changing the diagnosis of respiratory infections in critically ill patients Ricardo Serrano Garcia (Spain) EW037 8:45 Introduction Derek F.J. Brown (United Kingdom) EW038 8:55 Update on EUCAST 2014 EW049 12:00 A critical review of new biomarkers in VAP/HAP/ SCAP José M. Pereira (Portugal) Rafael Canton Moreno (Spain) EW039 9:15 Update on EUCAST methods and breakpoints EW050 12:30 Time is changing: monitoring VAP, VAT or IVAC? Gunnar Kahlmeter (Sweden) EW040 9:35 Internal quality control Robert L. Skov (Denmark) Posters EDUCATIONAL WORKSHOP 10: Antimicrobial susceptibility testing with EUCAST breakpoints and methods Joaquim Serra (Spain) Chairs, Speakers & Authors 8:45 – 12:45 ePosters 8:45 – 10:45 arranged with the ESCMID Study Group for Critically Ill Patients (ESGCIP) EW041 9:55 External quality assessment Derek F.J. Brown (United Kingdom) EW042 10:15 Moderated panel discussion on questions from 10:45 Coffee break 24th ECCMID / Barcelona Final Programme 29 General Information Exhibition the audience (part 1) Alasdair P. MacGowan (United Kingdom) Scientific Programme Saturday, 10 May 2014 11:00 – 13:00 HALL C EDUCATIONAL WORKSHOP 12: Bloodstream infections: opportunities for outcome improvement 11:00 – 13:00 EDUCATIONAL WORKSHOP 14: Elderly and chronic hepatitis C – to treat or not to treat? Group of ESCMID ID members interested in viral hepatitis (lead persons: Adriana Vince, Zagreb, Croatia and Heiner Wedermeyer, Hannover, Germany) Chairs: Mario U. Mondelli (Italy) Adriana Vince (Croatia) ESGBIS Chairs: Esther Calbo (Spain) Winfried V. Kern (Germany) EW051 11:00 Rapid diagnostic tests and early reporting EW059 11:00 What a difference the age makes? Clinical course of chronic hepatitis C in the elderly Jerzy Jaroszewicz (Poland) Martin Sundqvist (Sweden) EW052 11:30 Clinical evaluation and management EW060 11:30 Treatment of chronic hepatitis C in the elderly – are we missing opportunities? Antonella Cingolani (Italy) Pilar Retamar Gentil (Spain) EW053 12:00 Optimising therapy EW061 12:00 Management of chronic hepatitis C in the elderly Sibel Ascioglu (Turkey) not eligible for standard treatment Karin Lindahl (Sweden) EW054 12:30 Bacteraemia in difficult patients Winfried V. Kern (Germany) arranged with the ESCMID Study Group for Bloodstream Infections and Sepsis (ESGBIS) 11:00 – 13:00 HALL D EDUCATIONAL WORKSHOP 13: Basics of infections in travellers EW062 12:30 Elderly with chronic hepatitis C in real-life setting Adriana Vince (Croatia) 11:00 – 13:00 EFWISG Chairs: Kevin G. Kerr (United Kingdom) Eskild Petersen (Denmark) Chairs: Hakan Leblebicioglu (Turkey) Jon S. Friedland (United Kingdom) EW055 11:00 Infections with a long incubation period in returning travellers Francesco Castelli (Italy) EW056 11:30 Imported malaria in Europe – migrants and visiting-friends-and-relatives travellers as high risk groups Patricia Schlagenhauf (Switzerland) EW057 12:00 Misinterpretation of symptoms and overlooked illnesses in migrants – differentials to infections (case discussion) Christian Wejse (Denmark) EW058 12:30 Fever in returning travellers (case discussion) Nicholas J. Beeching (United Kingdom) 30 arranged with the ESCMID Study Group for Infections in Travellers and Migrants (ESGITM) 24th ECCMID / Barcelona Final Programme HALL F EDUCATIONAL WORKSHOP 15: When is a food-borne infection not a food-borne infection? ESGITM HALL E EW063 11:00 Risky reptiles and perilous pets: food-borne pathogens acquired from companion animals Malcolm Bennett (United Kingdom) EW064 11:30 Norovirus: kitchen hygiene versus hand hygiene Marion Koopmans (The Netherlands) EW065 12:00 Tracking down toxoplasmosis Eskild Petersen (Denmark) EW066 12:30 Campylobacter: do not just blame the chickens Philippe Lehours (France) arranged with the ESCMID Food- and Water-borne Infections Study Group (EFWISG) Scientific Programme Saturday, 10 May 2014 HALL G EDUCATIONAL WORKSHOP 16: Update on anaerobes: new methods bring new information about the bugs and their importance in health and disease 11:00 – 13:00 EDUCATIONAL WORKSHOP 18: Human parasites of the gut: epidemiology and diagnostic approaches in the molecular era ESGAI, TAE ESGCP, ESGMD Chairs: Elisabeth Nagy (Hungary) Kanita Dedic (Bosnia and Herzegovina) Chairs: Titia M. Kortbeek (The Netherlands) Paul Savelkoul (The Netherlands) EW067 11:00 What is hidden behind the name? Why taxonomic changes are key to elucidating the role of anaerobic pathogens Haroun N. Shah (United Kingdom) EW075 11:00 General introduction and epidemiology of common parasites of the human gut Marjan van Esbroeck (Belgium) EW068 11:30 'User friendly' identification of anaerobes: the role of MALDI-TOF Elisabeth Nagy (Hungary) EW069 12:00 Does antibiotic resistance exist in anaerobic bacteria? Disk diffusion for antimicrobial susceptibility testing and beyond Ulrik S. Justesen (Denmark) EW076 11:30 Classical diagnostic methods for detection of parasites Theo Mank (The Netherlands) EW077 12:00 Detection of parasites with molecular methods Spencer Polley (United Kingdom) Simone Caccio (Italy) anaerobes in a variety of conditions Diane M. Citron (United States) arranged with the ESCMID Study Group for Anaerobic Infections (ESGAI) and the Trainee Association of ESCMID (TAE) 11:00 – 13:00 HALL H arranged with the ESCMID Study Group for Clinical Parasitology (ESGCP) and the ESCMID Study Group for Molecular Diagnostics (ESGMD) 11:00 – 13:00 Overview & Programme EW078 12:30 Molecular typing of parasites EW070 12:30 Who would believe it? The unexpected role of HALL I HALL J EDUCATIONAL WORKSHOP 19: ESCMID guidelines for diagnosis and treatment of Aspergillus diseases ePosters 11:00 – 13:00 EFISG, ESGICH, ECMM, ERS and EACCI EW071 11:00 Dynamics of EBV viraemia and its relationship with the development of PTLD Helen E. Heslop (United States) Cornelia Lass-Flörl (Austria) EW080 11:30 Invasive aspergillosis in children Andreas H. Groll (Germany) EW081 12:00 Invasive aspergillosis in haematology and oncology Andrew J. Ullmann (Germany) EW072 11:30 Which population should be monitored? Rafael San Juan Garrido (Spain) EW073 12:00 Is there any role of antivirals and rituximab in the pre-emptive management of PTLD? Hans H. Hirsch (Switzerland) EW074 12:30 Role of reduction of immunosuppression, immune-adoptive therapy and other measures Oriol Manuel (Switzerland) arranged with the ESCMID Study Group for Infections in Compromised Hosts (ESGICH) Posters EW079 11:00 Diagnostic procedures Chairs, Speakers & Authors Chairs: Oriol Manuel (Switzerland) Stipan Jonjic (Croatia) EW082 12:30 Non-invasive aspergillosis David W. Denning (United Kingdom) arranged with the ESCMID Fungal Infection Study Group (EFISG); the ESCMID Study Group for Infections in Compromised Hosts (ESGICH); the European Confederation of Medical Mycology (ECMM); the European Respiratory Society (ERS) and the European Academy of Allergy and Clinical Immunology (EAACI) 24th ECCMID / Barcelona Final Programme 31 Exhibition ESGICH Chairs: Sevtap Arikan-Akdagli (Turkey) Jose M. Aguado Garcia (Spain) General Information EDUCATIONAL WORKSHOP 17: How to prevent the consequences of EBV infection in transplant recipients? Scientific Programme Saturday, 10 May 2014 13:30 – 15:30 HALL A SYMPOSIUM: What’s new in sepsis in 2014 ISF Chairs: Tom van der Poll (The Netherlands) Thierry Calandra (Switzerland) SY083 ISF Awardee Lecture: Protective role of the gut microbiota in pneumonia-derived sepsis Jacqueline Lankelma (The Netherlands) 13:30 – 15:30 ORAL SESSION: Lessons learned from Clostridium difficile molecular epidemiology Chairs: Mark H. Wilcox (United Kingdom) Ed J. Kuijper (The Netherlands) O001 Thierry Calandra (Switzerland) SY085 14:00 Prevention of sepsis in the ICU O002 Mihai Gheorghe Netea (The Netherlands) SY087 15:00 Combination antibiotic therapy for pneumococcal O003 arranged with the International Sepsis Forum (ISF) 13:30 – 15:30 HALL D O004 O005 and solid organ transplant recipients Catherine Cordonnier (France) O006 and CMV. What is new in the transplant setting? Oriol Manuel (Switzerland) SY091 15:00 Influenza vaccination. How can we improve its 24th ECCMID / Barcelona Final Programme 14:30 Dutch sentinel surveillance for Clostridium difficile infections shows stable hospital incidence since 2009, but a re-emergence of type 027 S.M. Van Dorp* (Leiden, The Netherlands), D.W. Notermans, S. De Greeff, E.J. Kuijper SY090 14:30 Other vaccines beside pneumococcal, influenza, 32 14:18 The changing epidemiology of Clostridium difficile ribotypes in Scotland between 2009-2013 C. Wiuff* (Glasgow, United Kingdom), A. Banks, D.J. Brown, D. Henderson, J.E. Coia, T. Inkster SY089 14:00 What can be expected from cytomegalovirus effectiveness? Pilar Perez-Romero (Spain) 14:06 Prevalence, proportions and diversity of Clostridium difficile PCR ribotypes in London from 2007-2012 D. Ready* (London, United Kingdom), C. Ryan, M. Cairns, H. Auburn, N. Murphy, C. Ling, N. Shetty, R. Manuel Chairs: Paolo A. Grossi (Italy) Carlos Lumbreras (Spain) vaccine? Vincent Emery (United Kingdom) 13:54 Household transmission of Clostridium difficile V.G. Loo, P. Brassard, M.A. Miller* (Montreal, Canada) SYMPOSIUM: Uncertainties in transplant vaccination SY088 13:30 Conjugated pneumococcal vaccine in stem cell 13:42 Increased diversity of C. difficile PCR-ribotypes across European countries and disparity of 027 prevalence; results of a European prevalence study of Clostridium difficile infection (EUCLID) K. Davies* (Leeds, United Kingdom), H. Ashwin, G.L. Davis, F. Lee, C.M. Longshaw, M.H. Wilcox SY086 14:30 Fungal sepsis sepsis: what is the evidence? Antonio Torres (Spain) 13:30 Whole genome sequencing demonstrates children are a potentially important reservoir for Clostridium difficile infections in adults D.W. Eyre* (Oxford, United Kingdom), N.E. Stoesser, G. Pill, A. Vaughan, D.W. Crook, T.E.A. Peto, A.S. Walker SY084 13:30 Year in review in sepsis Marc J.M. Bonten (The Netherlands) HALL E O007 14:42 Growth patterns of Clostridium difficile – correlation with strain types, binary toxin production and disease severity: results from a prospective cohort study S. Tschudin Sutter* (Basel, Switzerland), O. Braissant, A. Stranden, G. Bonkat, R. Frei, A.F. Widmer Scientific Programme Saturday, 10 May 2014 Chairs: Winfried V. Kern (Germany) Nur Benzonana (Turkey) O011 disease severity or recurrence K.A. Bauer* (Columbus, United States), J.E.W. Johnston, D.A. Goff, C.H. Cook, J.M. Balada-Llasat, P. Pancholi, J.E. Mangino stewardship – is there value in early reviewing at 48 hour post-antibiotic prescription? Y.X. Liew, D.M.M. TAY, M.P. Chlebicki, W. Lee, J. Teo, S.S.L. Tang, Y.P.J. Zhou, N.G.S. Chua, A. Kwa* (Singapore, Singapore) 15:18 Analysis of actual Clostridium difficile epidemiology in Germany based on a multi-centre bi-annual point prevalence study in European countries (EUCLID) L. Von Müller* (Homburg/Saar, Germany), D. Zevallos, A. Nimmesgern, M. Herrmann, EUCLID study group O012 management of prescribing for UTIs) study: a complex cluster intervention A. Vellinga* (Galway, Ireland), S. Duane, A. Callan, S. Galvin, M. Cormican, A.W. Murphy O013 13:30 – 15:30 SYMPOSIUM: Ticks and tick-borne pathogens Chairs: Gerold Stanek (Austria) Tatjana Avsic Zupanc (Slovenia) O014 Benoît Jaulhac (France) SY093 14:00 Rickettsial infection O015 TBD SY095 15:00 Emerging tick-borne viral infections 14:18 Effect of antibiotic stewardship programmes on Clostridium difficile incidence: a meta-analysis L.M. Feazel, A. Malhotra, E.N. Perencevich, P. Kaboli, D.J. Diekema, M.L. Schweizer* (Iowa City, IA, United States) SY094 14:30 Tick-borne encephalitis Koray Ergunay (Turkey) 14:06 Do we need to review and escalate the antimicrobial stewardship education in health and veterinary undergraduate courses in the United Kingdom? Results of a national survey E. Castro Sanchez* (London, United Kingdom), S. Farrell, L.D. Drumright, A.H. Holmes SY092 13:30 Lyme disease: from bench to bedside Pierre-Edouard Fournier (France) 13:54 Antibiotic prescribing in acute national health service hospitals; still lacking focus K. Hand, A.S. Walker, M.J. Llewelyn* (Brighton, United Kingdom) HALL F ESCAR, ESGBOR 13:42 The simple (supporting the improvement and Overview & Programme O010 13:30 Prospective review and feedback in antimicrobial ePosters 15:06 Clostridium difficile NAP1 does not influence ORAL SESSION: Improving antibiotic prescription quality O016 arranged with the ESCMID Study Group for Coxiella, Anaplasma, Rickettsia and Bartonella (ESCAR) and the ESCMID Study Group for Lyme Borreliosis (ESGBOR) 14:30 A prospective interrupted time series cross over study aimed at improving antibiotic quality at seven non-ICU wards S. Scheithauer* (Aachen, Germany), D. Manamayil, H. Häfner, B. Karasimos, ABS working group, S. Lemmen O017 14:42 Post-prescription review improves the in-hospital antibiotic use: a multi-centre randomised controlled trial P. Lesprit* (Suresnes, France), A. De Pontfarcy, M. Esposito-Farese, H. Ferrand, J.L. Mainardi, M. Lafaurie, F. Tubach, J.C. Lucet 24th ECCMID / Barcelona Final Programme 33 Posters O009 HALL G Chairs, Speakers & Authors outbreak caused by the epidemic BI/NAP1/027 strain of Clostridium difficile in a single centre in Israel Y. Wiener-Well* (Jerusalem, Israel), E. Ben-Chetrit, M. Abed-Eldaim, M.V. Assous, T. Miller-Roll, A. Adler 13:30 – 15:30 Exhibition 14:54 Clinical and molecular characteristics of an General Information O008 Scientific Programme Saturday, 10 May 2014 O018 14:54 No impact of electronic alerts on parenteral prescribing of antimicrobials with good bioavailability B. Huttner* (Geneva, Switzerland), C. Lovis, S. Harbarth O019 TAE Chairs: Polona Maver Vodicar (Slovenia) Erika Vlieghe (Belgium) 15:06 Financial evaluation of a multidisciplinary TD100 13:30 Welcome and TAE President's Address Polona Maver Vodicar (Slovenia) TD101 of prudent antibiotic prescribing teaching for undergraduate students C. Pulcini* (Nice, France), N. Frimodt-Møller, W.V. Kern, D. Nathwani, J. Rodríguez Baño, G.S. Simonsen, V. Vlahovic-Palcevski, I.C. Gyssens HALL I SYMPOSIUM: Application of new methods in medical microbiology and infection control TD102 14:15 The silent threat of bioterrorism – be prepared Maurizio Barbeschi (Switzerland) TD103 14:45 The challenges of outbreak detection and response Katrin Leitmeyer (Sweden) 15:15 Networking time TD104 15:45 Sepsis: think globally, treat locally – CM perspective Stefania Stefani (Italy) TD105 16:15 Sepsis: think globally, treat locally – ID perspective Erika Vlieghe (Belgium) ESGEM, ESGMD, ESGNI Chairs: Frederic Laurent (France) Francois Vandenesch (France) SY096 13:30 Next-generation sequencing: a one-stop shop for bacterial identification, antimicrobial susceptibility testing, virulence and subtyping? Dag Harmsen (Germany) SY097 14:00 Infection control within healthcare communities: using modern technology and network analysis Alexander W. Friedrich (The Netherlands) Rosanna Peeling (United Kingdom) SY099 15:00 Detecting polymicrobial causes of infections Chairs: Uwe Frank (Germany) Achilleas Gikas (Greece) SY106 16:30 Agreements and disagreements from international guidance documents Evelina Tacconelli (Germany) SY107 17:00 Identifying and tackling the challenges in local application Anna-Pelagia Magiorakos (Sweden) SY108 17:30 How to measure success of implementing guidelines Petra Gastmeier (Germany) SY109 18:00 Limitations of extracting the evidence for guidelines in infection control Kristina Bryant (United States) 34 24th ECCMID / Barcelona Final Programme HALL A SYMPOSIUM: Implementing international guidelines to reduce the spread of MDR Gram-negatives at national level Bernard La Scola (France) arranged with the ESCMID Study Group for Epidemiological Markers (ESGEM); the ESCMID Study Group for Molecular Diagnostics (ESGMD) and the ESCMID Study Group for Nosocomial Infections (ESGNI) arranged with the Trainee Association of ESCMID (TAE) 16:30 – 18:30 SY098 14:30 Modern diagnostics in the developing world 13:45 STDs – are they still hot? Beyond the typical case Mar Vera Garcia (Spain) 15:18 Cross-sectional European survey on principles 13:30 – 15:30 Room 133/134 TAE TRAINEES DAY: TAE Trainees Day – a time for trainees to share their knowledge under the supervision of seniors antimicrobial stewardship-team using an automatic day-2 intervention J.H. Dik* (Groningen, The Netherlands), J.R. Lo-Ten-Foe, B. Sinha, K.R. Wilting, Y.K. Kuychukova, P.N. Panday, R. Hendrix, A.W. Friedrich O020 13:30 – 16:45 Scientific Programme Saturday, 10 May 2014 HALL C O024 immunodeficiency virus type 1 envelope glycoproteins isolated from homosexual individuals homozygous for the CCR5 delta 32 allele Q. Jin* (Nanjng, China), Q. Niu, G. Alkhatib SYMPOSIUM: The Good, the Bad and the Ugly: recently approved and developmental anti-bacterials EPASG O025 immune escape in HIV-2 infection T. De Silva* (Sheffield, United Kingdom), A. Leligdowicz, J. Carlson, M. Garcia-Knight, S. Hue, N. Miller, L.M. Yindom, T. Dong, M. Cotten, S. Rowland-Jones Michael J. Rybak (United States) O026 17:30 Fidaxomicin patients treated with a raltegravir-containing regimen F. Falasca, C. Montagna, L. Mazzuti, G. D’Ettorre, P. Maida, V. Vullo, G. Antonelli, O. Turriziani* (Rome, Italy) Martin Llewelyn (United Kingdom) 18:00 Tigecycline Miguel Sanchez Garcia (Spain) arranged with the ESCMID PK/PD of AntiInfectives Study Group (EPASG) 16:30 – 18:30 O027 decreases in bone mineral density among HIV patients on CART I. Koga* (Tokyo, Japan), K. Seo, Y. Wakabayashi, S. Suzuki, Y. Yoshino, T. Kitazawa, I. Kurahashi, Y. Ota HALL D ORAL SESSION: New insights in epidemiology, resistance and pathogenesis to improve HIV management Chairs: Maria Rosaria Capobianchi (Italy) Giuseppe Pantaleo (Switzerland) O021 O022 16:54 Human immunodeficiency virus type 1 17:54 HIV-1 subtype distribution and mutations in the region of southwestern Greece; subtype A1 has surpassed subtype B and is the most prevalent strain N. Davanos, G. Panos, C. Gogos* (Patras, Greece), A. Mouzaki O029 18:06 X4 viruses prediction is significantly associated with nadir CD4 T cell below 100 cells /mm3 M. Sechet, C. Roussel, J.-L. Schmit, C. Saroufim, K. Ghomari, D. Merrien, F. Cordier, Y. Douadi, D. Liné, S. Castelain* (Amiens, France) 16:42 HIV tangles with coagulation activation during sepsis: results from a prospective observational study in Gabon M. Huson* (Amsterdam, The Netherlands), R. Kalkman, A.S. Alabi, J.O. Beyeme, M.P. Grobusch, J.C.M. Meijers, T. Van der Poll O023 O028 16:30 Changes in patterns of expression of human immunodeficiency virus type 1 spliced RNAs in diverse peripheral blood mononuclear cell types associated with disease progression Y. Vega, E. Delgado, C. Carrera, A. Mariño, A. Ocampo, C. Miralles, I. López-Miragaya, H. Álvarez, P. Ordóñez, M. Thomson* (Madrid, Spain) 17:42 Increased urinary NTX predicts progressive ePosters SY113 17:30 Dynamics of integrated and total HIV1-DNA in O030 18:18 The use of genotypic resistance in peripheral blood mononuclear cells (PBMCs) for modification of antiretroviral treatment in HIV patients who controlled viral replication E. Denes* (Limoges, France), P. Weinbreck, S. Ranger-Rogez Exhibition SY112 transcripts using splice sites near the 3' end of the viral genome are frequently expressed in vivo and enhance viral replication Y. Vega, E. Delgado, C. Carrera, A. Mariño, A. Ocampo, C. Miralles, I. López-Miragaya, H. Álvarez, P. Ordóñez, M. Thomson* (Madrid, Spain) 24th ECCMID / Barcelona Final Programme Overview & Programme 17:00 Ceftaroline Posters 16:30 Developmental beta-lactamase inhibitors in phase 2/3 clinical trials Ursula Theuretzbacher (Austria) SY111 17:18 Evidence for constrained CD8+ T-cell driven Chairs, Speakers & Authors Chairs: Fernando Baquero (Spain) Federico Pea (Italy) SY110 17:06 Broad coreceptor usage by human 35 General Information 16:30 – 18:30 Scientific Programme Saturday, 10 May 2014 16:30 – 18:30 HALL F O037 investigated by the use of whole genome sequencing M. Torpdahl* (Copenhagen, Denmark), S. Persson, K. Kiil, E.M. Nielsen ORAL SESSION: Epidemiology based on whole genome sequencing Chairs: Dag Harmsen (Germany) Hajo Grundmann (The Netherlands) O038 O031 16:30 Whole-genome molecular epidemiology of isolates causing increase in Neisseria meningitidis serogroup Y disease B. Törös* (Örebro, Sweden), S. Thulin Hedberg, M. Unemo, S. Jacobsson, D. Hill, H. Fredlund, H. Bratcher, K. Jolley, M. Maiden, P. Mölling O032 O033 O034 17:06 Better understanding of outbreaks of CA-MRSA USA300 (ST8-spa t008) by using whole-genome sequencing A.J. Sabat* (Groningen, The Netherlands), S. Hermelijn, V. Akkerboom, J.E. Degener, A.W. Friedrich O035 17:30 Combined analysis of whole genome MLST data and whole genome mapping data for clinical Campylobacter jejuni and C. coli isolates K. De Bruyne* (Sint-Martens-Latem, Belgium), R. Burggrave, A. Cody, M. Rijnsburger, H. Pouseele, M. Maiden, B. Pot O040 24th ECCMID / Barcelona Final Programme 18:18 An automated analysis pipeline for whole genome MLST data using BioNumerics® K. De Bruyne* (Sint-Martens-Latem, Belgium), L. Hauben, H. Pouseele, K. Janssens 16:30 – 18:30 HALL H SYMPOSIUM: Laboratory response to emerging viral diseases: from pathogen discovery to disease monitoring ECDC Chairs: Mikel J. Martinez (Spain) Ilaria Capua (Italy) SY114 16:30 Discovery and epizootic investigation of Schmallenberg virus infections in livestock Martin Beer (Germany) SY115 17:00 Discovery of Middle-East respiratory syndrome coronavirus and development of diagnostics Marion Koopmans (The Netherlands) SY116 17:30 Investigation of avian influenza A(H7N9) emergence in China George F. Gao (China) SY117 18:00 Monitoring emerging infectious diseases: role of public health laboratory networks Marc J. Struelens (Sweden) 36 18:06 Whole genome sequencing of isogenic drug- resistant Mycobacterium tuberculosis isolates shows antibiotic selection ensures genomic stability I. Bergval* (Amsterdam, The Netherlands), A. Schuitema, H. De Ronde, F. Coll, K. Mallard, A. Pain, R. McNerney, T. Clark, R. Anthony 17:18 Whole genome sequencing of Listeria isolates for surveillance and outbreak investigations J.T. Larsson, K. Kiil, E.M. Nielsen* (Copenhagen, Denmark) O036 O039 16:54 Spread of Clostridium difficile between humans and farm animals in The Netherlands revealed by whole genome sequencing W. Knetsch* (Leiden, The Netherlands), T. Connor, A. Mutreja, I. Sanders, S. Van Dorp, L. Lipman, L. Keessen, J. Corver, E. Kuijper, T. Lawley 17:54 Incorrectly annotated carbapenemase sequences in GenBank matter now more than ever M.J. Ellington* (Cambridge, United Kingdom), K. Apagyi 16:42 Comparison of bioinformatics approaches for whole genome sequencing analysis of Legionnaires' disease clusters D. Harmsen, K. Prior, E. Yakunin, L. Valinsky, V. Agmon, I. Grotto, J. Moran-Gilad* (Beit Kama, Israel) 17:42 A Danish Salmonella mikawasima outbreak arranged with the European Centre for Disease Prevention and Control (ECDC) Scientific Programme Saturday, 10 May 2014 16:30 – 18:30 HALL J SYMPOSIUM: Carbapenemases from prevention to treatment ESGARS Chairs: Luis Martinez-Martinez (Spain) Marek Gniadkowski (Poland) SY118 16:30 Carbapenemases from (not) detection to control Yehuda Carmeli (Israel) SY119 17:00 Update on OXA carbapenemases Patrice Nordmann (Switzerland) SY120 17:30 NDM dissemination Timothy R. Walsh (United Kingdom) SY121 18:00 KPC around the world Maria Virginia Villegas (Colombia) Exhibition Chairs, Speakers & Authors Posters ePosters Overview & Programme arranged with the ESCMID Study Group for Antimicrobial Resistance Surveillance (ESGARS) 24th ECCMID / Barcelona Final Programme 37 General Information ESCMID Online Lecture Library IN TH VISIT US ! EE FOR ECCMIDSCMID WO HAND R S-ON BARCELO LD AT TRIAL NA OF TH E OLL find lectures, abstracts, posters ... online Epidemiology of Candida bloodstream infections and antifungal susceptibility profiles: 10-year experience with 381 candidemia episodes in a tertiary care university centre Take your ECCMID home! Sehnaz ALP, Sevtap ARIKAN-AKDAGLI, Dolunay GULMEZ, Sibel ASCIOGLU, Omrum UZUN, Murat AKOVA Hacettepe University Faculty of Medicine, Ankara, Turkey C.albicans was always the dominant one [p-value for trend test between years 2001-2010 Introduction and Purpose Candida spp. are the most common fungal pathogens responsible for invasive diseases in humans. Among them, Candida albicans is in general responsible for more than half of all Candida infections. However, recent studies showed a remarkable shift from C.albicans to non-albicans Candida species (NAC) at least in a number of centres. Candida krusei is known to be intrinsically resistant to fluconazole. Moreover, a decreased susceptibility to fluconazole among other NAC, especially for Candida glabrata has been reported. The changing epidemiology of candidemia and antifungal susceptibility data have an impact on the preferred empirical antifungal regimen. This study was undertaken to (i) state for C.albicans and non-albicans Candida species (NAC) was non-significant (p>0.05)]. There were 213 Candida strains with available AST results (123 C.albicans, 37 Candida parapsilosis, 27 Candida tropicalis, 12 C. glabrata, 5 C. krusei, 3 Candida kefyr, 3 Candida guilliermondii and one of each Candida dubliniensis, Candida lusitaniae, Candida rugosa). Among them, there were 188 isolates tested against fluconazole, 145 isolates tested against voriconazole, 151 isolates tested against itraconazole and 99 isolates tested against caspofungin. Available AST results interpreted according to the currently approved species-specific CLSI breakpoints are given in Table-2. the ranking of Candida isolates among all positive blood cultures in our centre; ii) define the species distribution of Candida strains responsible for bloodstream infections and Table-2. The number of Candida isolates with available AST results interpreted according to explore whether there is any potential increase in non-albicans Candida as compared to currently approved CLSI breakpoints* C. albicans; and to (iii) determine the influence of currently approved CLSI breakpoints on interpretation of antifungal susceptibility test (AST) results. Candida Antifungal drug species (n) Methods C.albicans (122) We retrospectively evaluated our database and records of Mycology Laboratory from blood culture yielding Candida species were included in the study. In case of multiple - 17 1 - - 88 4 - 1 1 C.glabrata (8) C.krusei (3) Itraconazole C.parapsilosis (18) C.tropicalis (21) Antifungal drug 6 - 1 1 1 - 1 16 2 - - 11 6 - 4 Candida species (n) C.albicans (92) 1 1 PT - Results isolates among all positive blood cultures are shown in Table-1. R - During the study period, there were 18.426 positive blood cultures of which 858 grew infection. The distribution of species in 381 candidemia episodes and ranking of Candida I - PT 2 (18) Candida spp. For the current analysis 381 candidemia episodes were included. Candida 2 11 PT 20 C.albicans (93) ranked the fifth (ranged 4-7 during individual years) frequent cause of bloodstream SDD PT C.tropicalis currently approved CLSI breakpoints. Currently approved CLSI S C.krusei (5) Fluconazole results obtained from the archive of Mycology Laboratory were interpreted according to 119 C.glabrata (12) C.parapsilosis (22) January 2001 to December 2010. Patients who were reported to have at least one positive candidemia episodes during the same course, only the first episode was included. AST C.glabrata (10) Voriconazole C.krusei (4) C.parapsilosis (17) C.tropicalis (15) C.albicans (45) C.glabrata (4) Caspofungin C.krusei (3) C.parapsilosis (29) C.tropicalis (13) Currently approved CLSI S SDD I R 92 - - - IE IE IE IE 3 IE 1 - 17 - - - 15 - - - 45 - - - 2 - 2 - 2 - 1 - 28 - 1 - 13 - - - *Per the absence of any specific recommended breakpoints, species other than C.albicans, C.glabrata, C.krusei, C.parapsilosis and C.tropicalis Table-1. Distribution of candidemia episodes (n=381) according to isolated Candida species were not included in the susceptibility profile analysis CLSI: Clinical and Laboratory Standards Institute S: Susceptible 2001 Species C.albicans n (%) 13 (50.0) 2002 n (%) 21 (61.8) 2003 2004 n (%) n (%) 14 (66.7) 23 (65.7) n (%) 34 (58.6) 6 n (%) 35 (62.5) 2007 n (%) 31 (65.9) 2008 n (%) 16 (42.1) 9 2009 n (%) 16 (51.6) 2010 n (%) 19 (54.3) Total n (%) 222 (58.3) 58 3 8 6 9 4 8 (11.5) (23.5) (9.5) (8.6) (10.3) (10.7) (19.1) (23.7) (12.9) (22.9) (15.2) C.tropicalis 3 (11.5) 2 (5.9) 5 (23.8) 4 (11.4) 11 (18.9) 11 (19.6) 4 (8.5) 6 (15.8) 4 (12.9) 1 (2.9) 51 (13.4) 3 (11.5) 1 (2.9) - 3 (8.6) 2 (3.4) 3 (5.4) 1 (2.1) 5 (13.2) 4 (12.9) 4 (11.4) 26 (6.8) - - - - 1 (1.7) 1 (2.1) 2 (5.3) - 1 (2.9) 5 (1.3) C.krusei 3 2006 C.glabrata C.parapsilosis 2 2005 C.kefyr 1 (3.8) - - - - 2 (6.5) 1 (2.9) 5 (1.3) Other NAC* 3 (11.5) 2 (5.9) - 2 (5.7) 4 (6.9) 1 (1.8) - - 1 (3.2) 1 (2.9) 14 (3.7) 26 34 21 35 58 56 47 38 31 35 381 6 4 7 7 4 4 6 6 4 6 5 - - 1 (2.1) SDD: Susceptible dose dependent I: Intermediate R: Resistant PT: Poor target to be treated with the denoted drug IE: Insufficient evidence Conclusions (1) Candida spp. play a prominent role among the common bloodstream isolates in our centre. (2) Among all Candida species, C. albicans has been the most common cause of candidemia and this trend has not changed during the study period. (3) Resistance to tested antifungal drugs is not common among our candidemia isolates except for itraconazole. (4) We observed decreased susceptibility to fluconazole for our C.glabrata strains. This is possibly due to the intrinsic feature of this species for susceptibility to fluconazole and the conclusive nonexistence of the category of “susceptible” in the currently revised breakpoint scale. References 1. Clinical and Laboratory Standards Institute. Reference method for broth dilution antifungal susceptibility testing of yeasts; approved standard, 3rd ed., CLSI Total Ranking among all positive blood cultures *Other non-albicans Candida species (NAC) included in this study were: 4 C.guilliermondii, 4 C.lusitaniae, 2 C.inconspicua/norvegensis, 2 C.rugosa, 1 C.dubliniensis, 1 C.colliculosa document M27-A3. Clinical and Laboratory Standards Institute 2008, Wayne, PA. P 2. Cuenca-Estrella M, Bernal-Martinez L, Buitrago MJ, et al. Update on the epidemiology and diagnosis of invasive fungal infection. Int J Antimicrob Agent Agents 2008;32 Suppl 2:S143-7. 3. Nguyen MH, Peacock JE, Morris AJ, et al. The changing face of candidemia: emergence of non-Candida albicans species and antifungal resistance. Am J Med 1996;100:617-23. -Wild-type MIC distributions, 4. Pfaller MA, Andes D, Diekema DJ, Espinel-Ingroff ff f A, Sheehan D; CLSI Subcommittee for Antifungal Susceptibility Testing. T epidemiological cutoff ff f values and species-specific clinical breakpoints for fluconazole and Candida: time for harmonization of CLSI and EUCAST broth microdilution methods. Drug Resist Updat 2010;13:180-95. 5. Pfaller MA, Castanheira M, Messer SA, Moet GJ, Jones RN. Echinocandin and triazole antifungal susceptibility profiles for Candida spp., Cryptococcus neoformans, and Aspergillus fumigatus: application of new CLSI clinical breakpoints and epidemiologic cutoff f values to characterize resistance in the ff SENTRY R Antimicrobial Surveillance Program (2009). Diagn Microbiol Infect Dis 2011;69:45-50. RY Over 3’500 abstracts, Around 2’000 (e)posters, More than 250 slide-sets and recorded webcasts Check it out online at www.escmid.org/OLL Scientific Programme Sunday, 11 May 2014 7:45 – 8:45 HALL A MEET-THE-EXPERT SESSION: Sepsis management beyond antibiotics ESGBIS Experts: W. Joost Wiersinga (The Netherlands) Jean-Louis Vincent (Belgium) arranged with the ESCMID Study Group for Bloodstream Infections and Sepsis (ESGBIS) 7:45 – 8:45 HALL D MEET-THE-EXPERT SESSION: Outbreak of P. aeruginosa in your hospital and you think it could be water-related? Want to know what to do next? 7:45 – 8:45 HALL I MEET-THE-EXPERT SESSION: Screening for carbapenemase production, molecular and phenotypic methods Experts: Laurent Poirel (Switzerland) Christian G. Giske (Sweden) 7:45 – 8:45 HALL J MEET-THE-EXPERT SESSION: New viruses: pathogens or innocent bystanders? Experts: Ulrike Wieland (Germany) Albert D.M.E. Osterhaus (The Netherlands) EFWISG HALL F MEET-THE-EXPERT SESSION: Addressing the problem of MDR Neisseria gonorrhoeae SY128 7:45 – 8:45 ePosters SY129 9:30 The CDC/HICPAC recommendations for SSI prevention: what is new after 15 years? Joseph S. Solomkin (United States) HALL H MEET-THE-EXPERT SESSION: Controversies in treatment of malaria and crimean-congo haemorrhagic fever ESGITM Experts: Hakan Leblebicioglu (Turkey) Eskild Petersen (Denmark) 9:00 The burden and prevention of SSI: a global perspective from WHO Benedetta Allegranzi (Switzerland) Experts: Michelle Cole (United Kingdom) Magnus Unemo (Sweden) Chairs: Werner Zimmerli (Switzerland) Jean-Christophe Lucet (France) SY130 10:00 Barriers to implementing good antibiotic prophylaxis and how to overcome them Petra Gastmeier (Germany) SY131 Posters 7:45 – 8:45 SYMPOSIUM: What is new on surgical site infection prevention? Overview & Programme arranged with the ESCMID Food- and Water-borne Infections Study Group (EFWISG) 10:30 Controversial issues in the prevention of surgical site infections Jan A.J.W. Kluytmans (The Netherlands) Chairs, Speakers & Authors HALL A arranged with the ESCMID Study Group for Infections in Travellers and Migrants (ESGITM) Exhibition 9:00 – 11:00 24th ECCMID / Barcelona Final Programme 39 General Information Experts: Michael Weinbren (United Kingdom) Matthias Trautmann (Germany) Scientific Programme Sunday, 11 May 2014 9:00 – 11:00 HALL D O047 10:12 Outpatient parenteral antimicrobial therapy (OPAT) for the management of cellulitis: an eighteen-month review at a large general hospital in the UK P. Minagh, A. Hamda, M. Murdoch, T. Vaghela, P. Seetulsingh* (Watford, United Kingdom) ORAL SESSION: Monitoring antibiotic use Chairs: Céline Pulcini (France) Inge C. Gyssens (The Netherlands) O041 9:00 Systemic outpatient antibiotic use in urban O048 10:24 Drivers’ identification and intervention study and rural areas in Japan Y. Gu* (Sendai, Japan), A. Versporten, S. Coenen, N. Adriaenssens, H. Goossens, M. Kaku O042 9:12 Antimicrobial consumption in Brazil: impact of restricting over-the-counter sales M.L.N. Moura* (São Paulo, Brazil), I. Boszczowski, R. Lobo, N. Mortari, A.S. Levin O043 antibiotic use and vaccination uptake amongst 15-18 year olds: an international project M.K.D. Hawking* (Gloucester, United Kingdom), D.M. Lecky, P. Touboul Lundgren, E.K. Aldigs, H.A. Abdulmajed, D. Hadjichambi, E. Ioannidou, C.A.M. McNulty O050 9:00 – 11:00 Chairs: Kim Lewis (United States) Thomas Bjarnsholt (Denmark) SY132 24th ECCMID / Barcelona Final Programme 9:00 Bacterial biofilms in VAP: implications for diagnosis and treatment Laia Fernandez-Barat (Spain) 10:00 Complications of outpatient parenteral antimicrobial therapy – a four-year service review M.C. Cabeza Brasa* (London, United Kingdom), M. Cotter, S. Mullen, A. Breathnach, M. Laundy, P. Riley, T. Planche HALL F SYMPOSIUM: Exploring and treating biofilms SY133 40 10:48 Polymyxin B consumption and resistance in Gram-negative bacteria D.R. Falci* (Porto Alegre, Brazil), R.C.F. Da Silva, L.S. Puga, D.M. Simas, C.P. Baldin, I.I. Limberger, F.M. Pinto, A.P. Zavascki 9:48 Hospital antibiotic use in Europe: are comparisons relevant? C. Dumartin* (Bordeaux, France), K. De With, P. Parneix, A.M. Rogues O046 10:36 Using social marketing to improve appropriate 9:36 National parenteral glycopeptide consumption figures poorly reflect the MRSA situation in the hospital sector and EU/EAA countries between 2007 and 2011 K. Weist* (Stockholm, Sweden), O. Heuer, L. Diaz-Högberg, C. Suetens, D.L. Monnet, A. Muller, Network Members of the ECDC Surveillance Networks EARS-Net ESAC-Net and HAI-Net O045 O049 9:24 Healthcare-associated infections and antimicrobial use in European long-term care facilities (HALT): results of two point prevalence surveys K. Latour* (Brussels, Belgium), B. Jans, M.L. Moro, F. Fitzpatrick, E. Ricchizzi, T. Dillane, B. Cookson, J. Fabry, C. Suetens O044 for containing an OXA-48 producing Klebsiella pneumonia outbreak in a renal unit in London M. Gharbi* (London, United Kingdom), M. Gilchrist, L.S.P. Moore, E.T. Brannigan, K.B. Bamford, A.H. Holmes 9:30 Dissecting the S. aureus biofilmome Surbhi Malhotra-Kumar (Belgium) SY134 10:00 Anti-biofilm agents: where are we? Andrej Trampuz (Germany) SY135 10:30 In vitro models for the study of antibiotic PK/PD in biofilms Francoise van Bambeke (Belgium) Scientific Programme Sunday, 11 May 2014 O058 10:24 Leishmaniasis in Turkey: in vitro and in vivo assessments of emerging resistance to meglumine antimonate among the Leishmania tropica isolates from Anatolia A. Ozbilgin, M. Harman, C. Gunduz, I. Cavus, O. Kurt* (Istanbul, Turkey), Y. Ozbel ORAL SESSION: News in travel, tropical and parasitic infections Chairs: Titia M. Kortbeek (The Netherlands) Joaquim Gascon (Spain) O059 10:36 Leishmaniasis in Turkey: comparison of healthy controls than in gastroenteritis cases by molecular detection in The Netherlands M. Boer de* (Hengelo, The Netherlands), A. Zanden vd, L. Bruijnesteijn, T. Schuurs, T. Mank, G. Ruijs, B. Mulder infection/AIDS in a population in Mozambique R. Gálvez-López, D. Torrús-Tendero* (Alicante, Spain), E. Cobos, E. Nacarapa, M.E. Verdú O054 9:48 Results of a collaborative screening programme of imported diseases in immigrant population between a tropical medicine unit and Spanish red cross I. Piñero, D. Caravia, B. Pedrayes, M. Rodriguez, J. Fernandez, E. Carus, C. Suarez, A. Rodriguez-Guardado* (Oviedo, Spain) O056 10:00 One-stop blood testing for TB, HIV, and hepatitis B/C in new migrants S. Hargreaves* (London, United Kingdom), F. Seedat, J. Car, R. Escombe, S. Hasan, J. Eliahoo, J. Friedland O057 10:48 The carcinogenic human liver fluke, Opisthorchis viverrini: disease in fish indicates patient infection in rural community of Thailand K. Natthawut* (Muang, Thailand), R. Rujirakul, J.K. Soraya 9:36 Risk factors for ARDS development in severe imported malaria: a retrospective study N. Rocha Pereira* (Anta-Espinho, Portugal), C. Figueiredo, L. Santos, A. Ferreira, C. Lima Alves, P. Figueiredo Dias, A. Sarmento O055 O060 10:12 Leishmaniasis in Turkey: establishment of cutaneous leishmaniasis models on hamsters (Mesocricetus auratus) using Leishmania tropica, L. infantum and L. major isolates obtained from Turkish patients A. Ozbilgin, M. Harman, I. Cavus, O. Kurt* (Istanbul, Turkey) 9:00 – 11:00 HALL I Overview & Programme 9:24 Clinical course of malaria in patients with HIV SYMPOSIUM: MALDI-TOF mass spectrometry: ongoing revolution in clinical microbiology Chairs: Paul Savelkoul (The Netherlands) Alexander W. Friedrich (The Netherlands) ePosters O053 isoenzyme, real-time PCR and MALDI-TOF analyses for the identification of Leishmania species in clinical samples A. Ozbilgin, O. Kurt, I. Akyar* (Istanbul, Turkey), G. Culha, F. Zeyrek, C. Gunduz, T. Oyur, F. Pratlong, P. Bastien, Y. Ozbel SY136 9:00 MALDI-TOF: Challenges and solutions in identification of bacteria from isolated colonies Robin Patel (United States) SY137 Posters 9:00 Significantly more Dientamoeba fragilis in 9:30 Clinical impact of MALDI-TOF on blood cultures Olivier Vandenberg (Belgium) SY138 10:00 MALDI-TOF: usefulness for typing, taxonomy and epidemiology Jean-Marc Rolain (France) Chairs, Speakers & Authors O051 SY139 10:30 MALDI-TOF: a new tool to rapidly assess the antibiotic susceptibility Sören Schubert (Germany) Exhibition HALL H 24th ECCMID / Barcelona Final Programme 41 General Information 9:00 – 11:00 Scientific Programme Sunday, 11 May 2014 9:00 – 11:00 HALL J O067 aureus infection: results from a population-based case-control genome-wide association study G. Delorenze, C. Nelson, W. Scott, A. Allen, G.T. Ray, V. Fowler* (Durham, NC, United States) ORAL SESSION: Basic science: pathogenesis and epidemiology of Gram-positive bacteria Chairs: Anna Norrby-Teglund (Sweden) Francois Vandenesch (France) O061 O062 O064 9:36 Clindamycin and intravenous immunoglobulin influence group A Streptococcus virulence factor activity A. Tarnutzer* (Zurich, Switzerland), C.M. Zuercher, F. Andreoni, K. Schilcher, R.A. Schuepbach, A.S. Zinkernagel O065 O069 O070 11:30 – 12:30 dynamics modulate intracellular virulence in Staphylococcus aureus J.P. Rasigade* (Lyon, France), C. Dunyach-Remy, A. Sapin, N. Messad, S. Trouillet-Assant, J.P. Lavigne, F. Laurent 42 24th ECCMID / Barcelona Final Programme HALL A ORAL SESSION: Deep insights in mycobacteria: genomics and susceptibility Chairs: Erik C. Böttger (Switzerland) Dick van Soolingen (The Netherlands) O086 11:30 Onsite genome screening to monitor multidrug- resistance in Mycobacterium tuberculosis in a region with considerable pathogen genetic diversity and drug resistance S. Sengstake* (Amsterdam, The Netherlands), N. Bablishvili, N. Bzekalava, N. Tadumaze, M. Akhalaia, N. Tukvadze, R. Aspindzelashvili, R. Anthony, I. Bergval 9:48 Antimicrobial activity against intra-osteoblastic 10:00 From colonisation to invasion: phage 10:48 Selection of low-level mupirocin-resistance in hospital but not community MRSA clones J. Hughes* (London, United Kingdom), R. Stabler, T. Karadag, N. Desai, A. Patel, J.A. Otter, J.D. Edgeworth, O. Tosas Auguet Staphylococcus aureus: a new therapeutic concept for bone and joint infection? F. Valour, N. Riffard, S. Trouillet-Assant, J.P. Rasigade, C. Chidiac, F. Vandenesch, T. Ferry, F. Laurent* (Lyon, France) O066 10:36 Staphylococcus aureus spa-type t437: a clone with emerging public health importance encroaching upon Europe C. Glasner* (Groningen, The Netherlands), G.N. Pluister, J.P. Arends, M. Heck, H.T. Westh, H. Grundmann, J.M. Van Dijl 9:24 Pathogenesis of necrotising soft tissue infections: analyses at the local tissue site in patient biopsies and in a novel 3D skin model N. Siemens, L. Johansson, B. Chakrakodi, INFECT Study Group, M. Svensson, A. Norrby-Teglund* (Stockholm, Sweden) 10:24 How MRSA behaves inside the household: the community-onset Staphylococcus aureus household cohort (COSAHC) study, Australia C. Bennett* (Burwood, Australia), G. Coombs, G. Wood, E. Bogatyreva, B. Howden, P. Johnson 9:12 Complement factor H deficiency increases mortality in experimental pneumococcal meningitis through C3 depletion E.S. Kasanmoentalib* (Amsterdam, The Netherlands), M. Valls Seron, M.C. Brouwer, D. Van de Beek O063 O068 9:00 Genomic monitoring of within-host evolution of Streptococcus pneumoniae indicates strong selective pressure M.R. Oggioni* (Leicester, United Kingdom), L. Furi, S. Arioli, D. Mora, A. Gerlini 10:12 Human genetic susceptibility to Staphylococcus O087 11:42 Non-steroid anti-inflammatory drugs to tackle drug resistance of Mycobacterium tuberculosis S. Bhakta* (London, United Kingdom) Scientific Programme Sunday, 11 May 2014 aminoglycoside- and macrolide-resistance in clinical isolates of Mycobacterium abscessus F. Mougari* (Paris, France), R. Amarsy, L. Raskine, C. Bernard, F. Brossier, E. Cambau Parity Commission, TAE Chairs: Nur Benzonana (Turkey) TBD SY143 11:30 Scientific career in adverse economic and social conditions Stipan Jonjic (Croatia) SY144 12:00 Research in extraordinary times of war Mirsada Hukic (Bosnia and Herzegovina) 12:18 Analysis of the genomic variations observed in persistent infection or reactivation by Mycobacterium tuberculosis and evaluation of their impact L. Pérez-Lago, Y. Navarro, I. Comas, M. Herranz, M.J. Ruiz Serrano, P. Montilla, E. Bouza, D. Garcia de Viedma* (Madrid, Spain) 11:30 – 12:30 HALL B KEYNOTE LECTURE: Genomic diagnostics: transforming clinical and public health microbiology practice 11:30 – 12:30 ESGCD Chairs: Ed J. Kuijper (The Netherlands) Emilio Bouza Santiago (Spain) SY145 11:30 Clostridium difficile in food and in production Dag Harmsen (Germany) 11:30 – 12:30 HALL E SYMPOSIUM: Emergence of Clostridium difficile infections outside healthcare facilities animals Scott Weese (Canada) Chair: Alexander W. Friedrich (The Netherlands) KL140 arranged with the Parity Commission (PC) and the Trainee Association of ESCMID (TAE) ePosters O090 SYMPOSIUM: Great scientific success with scarce resources. Is money issue a crucial point? 12:06 Increased tolerance to transient exposures to rifampicin of M. tuberculosis strains of the Beijing genotype compared to strains with the EAI genotype A.L. Den Hertog* (Amsterdam, The Netherlands), S. Menting, D. Van Soolingen, R.M. Anthony HALL D SY146 12:00 Risk factors and a clinical prediction score for CDI acquired in the community Marjolein Hensgens (The Netherlands) HALL C SYMPOSIUM: Macrolides are still safe and effective to be used in clinical practice. Pro / Con debate arranged with the ESCMID Study Group for Clostridium difficile (ESGCD) Posters O089 11:30 – 12:30 Overview & Programme 11:54 Phenotypic and genetic characterisation of Chairs, Speakers & Authors Chairs: Jordi Carratala (Spain) Murat Akova (Turkey) SY141 11:30 Yes, we can use them unequivocally Francesco B. Blasi (Italy) SY142 12:00 Beware! Too many drug interactions and side Exhibition effects... James Chalmers (United Kingdom) 24th ECCMID / Barcelona Final Programme 43 General Information O088 Scientific Programme Sunday, 11 May 2014 11:30 – 12:30 HALL F ORAL SESSION: Automation in diagnostic bacteriology 11:30 – 12:30 ORAL SESSION: MDR Acinetobacter baumannii Chairs: Gerard Lina (France) Johan Van Eldere (Belgium) O071 11:30 Digital microscopic quantification of bacteria, Chairs: Carmen Torres (Spain) Luisa M. V. Peixe (Portugal) O076 11:30 Identification of a new integron-borne blaIMP-10 leukocytes and epithelial cells coupled with detection of leukocyte esterase and nitrites for the screening of urine submitted for culture A. Tessari* (Rovigo, Italy), N. Osti, A. Astolfi, M. Boldrin, P. Gotto, C. Scolaro, M. Scarin O072 11:42 Evaluation of manual versus automated in carbapenem-resistant Acinetobacter baumannii (ACB) clinical isolates in Brazil R. Cayô* (São Paulo, Brazil), F. Rodrigues-Costa, A.P. Matos, W. Martins, K.E. Da Silva, G. Braun, L.C.C. Fehlberg, C.G. Carvalhaes, A.C. Gales O077 11:42 The effect of closely related OXA-51 variants inoculation A. Croxatto* (Lausanne, Switzerland), K. Dijkstra, G. Prod'hom, G. Greub O073 O074 on carbapenem susceptibility in Acinetobacter baumannii E. Zander* (Cologne, Germany), H. Seifert, P.G. Higgins 11:54 Comparison of ESwab™ collection and WASP® automation with dacron swab and manual plating for smear interpretation and detection of pathogens associated with wound specimens K. Chapin* (Providence, United States), L. McVeigh, M. Andrade, A. Angelone, K. Beach 12:06 Evaluation of Copan SnotBuster™ for improved O078 11:54 AbaGI-R, a genomic island in Acinetobacter baumannii highly correlated with multidrug resistance Y. Jiang, Y. Feng* (Hangzhou, China), H. Zhou, Z.H. Zhou, J.S. Ji, Y.F. Wang, Y. Chen, Y.S. Yu O079 12:06 Genetic changes which maintain bacterial fitness sputum culture results B. Buchan, T. Mackey* (Oak Creek, United States), E. Beck, J. Connolly, N. Ledeboer O075 12:18 Validation of the smart incubator system HALL G and virulence after exposure to colistin M.E. Wand* (Salisbury, United Kingdom), L.J. Bock, L. Bonney, J.M. Sutton O080 12:18 Synergistic interaction of AdeR and AdeS on the (SIS) [bioMérieux] for prolonged incubation of fastidious bacteria C. Fulchiron, M. Guicherd, L. Munoz, D. Archeny, S. Ghirardi, A. Van Belkum, G. Durand* (La Balmeles-Grottes, France) expression of the RND-efflux pump AdeB confers decreased susceptibility to a broad range of antibiotics in Acinetobacter baumannii J. Nowak* (Cologne, Germany), T. Schneiders, H. Seifert, P.G. Higgins 11:30 – 12:30 HALL H KEYNOTE LECTURE: The great filter: parasitic infections of the liver ESGCP Chair: Miriam José Alvarez Martinez (Spain) 44 24th ECCMID / Barcelona Final Programme KL147 Peter Chiodini (United Kingdom) arranged with the ESCMID Study Group for Clinical Parasitology (ESGCP) Scientific Programme Sunday, 11 May 2014 ORAL SESSION: Emerging resistance in fungi 11:30 – 12:30 SYMPOSIUM: Viral opportunists in the critically ill patient Chairs: Sevtap Arikan-Akdagli (Turkey) Jesus Guinea (Spain) 11:30 Intra-abdominal candidiasis is an important reservoir for the emergence of FKS mutations among Candida glabrata and Candida albicans R.K. Shields, M.H. Nguyen, C.J. Clancy* (Pittsburgh, United States) O082 11:54 Post-treatment antifungal resistance among colonising Candida isolates in candidaemia patients: preliminary results from a systematic multi-centre study R.H. Jensen* (Copenhagen, Denmark), H.K. Johansen, L.M. Søes, L.E. Lemming, F.S. Rosenvinge, L. Nielsen, B.R.S. Olesen, L. Kristensen, C. Leitz, M. Arendrup O084 SY148 11:30 Basic aspects of cytomegalovirus subversion and immune control Ineke J. M. Ten Berge (The Netherlands) SY149 12:00 Clinical science: when to ignore, observe or treat? Ajit P. Limaye (United States) 11:42 Functional and genomic correlates of heteroresistance to fluconazole in Candida glabrata R. Ben-Ami* (Tel Aviv, Israel), O. Zimmerman, T. Finn, A. Novikov, N. Blutraich, J. Berman O083 Chairs: Jordi Rello (Spain) Hans H. Hirsch (Switzerland) 14:30 – 15:30 HALL A SYMPOSIUM: The year in Infection Control Chair: Jan A.J.W. Kluytmans (The Netherlands) SY150 14:30 Part I Barry Cookson (United Kingdom) SY151 15:00 Part II Christina Vandenbroucke-Grauls (The Netherlands) 12:06 Circulation of moulds between clinical and 12:18 Azole resistance mechanisms found among Chairs, Speakers & Authors fluconazole-resistant Candida albicans clinical isolates: report from the sentry antifungal resistance programme L.M. Deshpande, M.A. Pfaller, L.N. Woosley, R.N. Jones, M. Castanheira* (North Liberty, IA, United States) Exhibition O085 Posters environmental reservoirs in a COPD patient population: emergence of Aspergillus fumigatus azole-resistance in the north of France C. Dauchy, A. Standaert-Vitse, O. Le Rouzic, S. Nseir, E. Dei-Cas, E.M. Aliouat, S. Fry, E. Frealle* (Lille, France) 24th ECCMID / Barcelona Final Programme 45 General Information O081 HALL J Overview & Programme HALL I ePosters 11:30 – 12:30 Scientific Programme Sunday, 11 May 2014 14:30 – 15:30 HALL B ORAL SESSION: Hepatitis B treatment and management TAE, Professional Affairs Subcommittee, UEMS-ID, UEMS-MM Chairs: Mario U. Mondelli (Italy) Hilpi Rautelin (Sweden) 14:30 Different facilities and trends in the management of chronic hepatitis B virus infection in Europe R. Ozaras* (Istanbul, Turkey), G. Corti, S. Ruta, K. Lacombe, M. Mondelli, W. Irving, M. Puoti, D. Salmon, H. Leblebicioglu, J. Arends O092 14:42 Efficacy and safety of tenofovir treatment at 240 weeks in patient with chronic HBV infection A. Perrella* (Naples, Italy), A. Galeota Lanza, C. Sbreglia, G. Di Costanzo, P. Bellopede, O. Perrella SY153 14:30 Training in infectious diseases Nicholas J. Beeching (United Kingdom) SY154 14:45 Training in clinical microbiology Truls Michael Leegaard (Norway) SY155 15:00 Trainees viewpoints and survey results Polona Maver Vodicar (Slovenia) SY156 15:15 Discussion O093 14:54 Hepatitis B virus in pregnancy: evaluation of antiviral treatment efficacy and risk of perinatal transmission A. Batirel* (Istanbul, Turkey), I.I. Balkan, O. Karabay, K.K. Yasar, F. Duygu, I.N. Hakyemez, R. Guner, A. Ogutlu, A.D. Celik, M. Dogan O094 15:06 Effectiveness of hepatitis B virus vaccination programme in Egypt: seroprotection and HBV infection I. Salama, S. Samai, Z. Said* (Cairo, Egypt), M. El-Sayed, S. Salama, T. Rabah, A. Abdel Mohsin, S. Hemida, A. Hassanin, N. Abd Alhalim O095 15:18 A clinical trial on atorvastatin treatment and efficacy of hepatitis B vaccinations N. Jonaidi Jafari* (Tehran, Iran), M. Izadi, A. Saburi, S.M. Alavian, R. Ranjbar, M. Safiabadi, A. Hosseinpour, M. Mohammad Jonaidi 14:30 – 15:30 HALL C KEYNOTE LECTURE: Knowledge and social norms shaping the discovery, use, and resistance trends of antimicrobial agents Chair: Nienke van de Sande-Bruinsma (Denmark) KL152 Fernando Baquero (Spain) arranged with the Trainee Association of ESCMID (TAE); the Professional Affairs Subcommittee (PAS); European Union of Medical Specialists (Infectious Disease and Medical Microbiology Section) 14:30 – 15:30 Chairs: Marc Lecuit (France) Annelies Zinkernagel (Switzerland) SY157 14:30 Listeria genomics Sylvain Brisse (France) SY158 15:00 Listeriosis: a prospective study of 800 cases Caroline Charlier-Woerther (France) 14:30 – 15:30 Final Programme HALL F SYMPOSIUM: Why are some carbapenemases successful? Chairs: Ana Gales (Brazil) Maria Virginia Villegas (Colombia) SY159 14:30 Why are some carbapenemases more successful than others? Rafael Canton Moreno (Spain) do we have the right ones? Yehuda Carmeli (Israel) 24th ECCMID / Barcelona HALL E SYMPOSIUM: Listeria and listeriosis SY160 15:00 Beta-lactamase and breakpoints: 46 HALL D SYMPOSIUM: Training in infection in Europe – progress in curricula and assessments Chairs: Karin Lindahl (Sweden) Resat Ozaras (Turkey) O091 14:30 – 15:30 Scientific Programme Sunday, 11 May 2014 ORAL SESSION: An update on malaria Chairs: Jose Luis Martinez (Spain) Emmi Andersson (Sweden) O101 children A.E. Budding* (Amsterdam, The Netherlands), T.G.J. De Meij, F.M. Jansen, E. De Groot, A.A. Van Bodegraven, P.H.M. Savelkoul predictors of malaria in patients with fever returning from tropical countries D. Torrús-Tendero* (Alicante, Spain), A. Zurita, H. Pinargote, S. Reus, V. Boix, E. Merino, M. Andreu, A. Gimeno, A. Tello, J. Portilla 14:42 Microbiome data reveals gut bacteria characteristic of individuals with and without Clostridium difficile infection A.M. Schubert* (Ann Arbor, United States), M.A.M. Rogers, C. Ring, J. Mogle, J.P. Petrosino, V.B. Young, D.M. Aronoff, P.D. Schloss O102 molecular diagnosis of malaria M. Manser, D. Nolder, S. Polley, C. Sutherland, P. Chiodini* (London, United Kingdom) O103 O098 14:54 Dynamics of the nasopharyngeal microbiota O104 15:06 Airway microbiota in cystic fibrosis patients with O105 15:18 Altered proteobacteria composition in patients with acute uncomplicated diverticulitis A. Eck* (Amsterdam, The Netherlands), L. Daniels, M.A. Boermeester, J.A. Bogaards, P.H.M. Savelkoul, A.E. Budding 15:06 How did travellers use rapid diagnostic tests for malaria provided by a travel-clinic during their trip? A cohort study D. Berthod* (Lausanne, Switzerland), J. Rochat, R. Voumard, B. Genton, V. D'Acremont a severe decline in lung function E. Fiscarelli* (Rome, Italy), P. Paganin, V. Tuccio, M. Chiancianesi, G. Taccetti, V. Lucidi, A. De Alessandri, A. Mengoni, A. Bevivino O100 14:54 Retrospective cohort study on the outcome of acute respiratory distress syndrome due to malaria T. Chandra* (Manipal, India), A. Gupta, A. Chakrapani, M. Varm in healthy infants within the first year of life: a prospective study M. Mika* (Berne, Switzerland), I. Mack, U. Frey, P. Latzin, M. Hilty O099 14:42 External quality assessment scheme for the Overview & Programme O097 14:30 Epidemiological, clinical and laboratory ePosters 14:30 Core gut microbiome and temporal stability in Chairs: Michael Ramharter (Austria) TBD 15:18 Preferred choice of travellers visiting low-risk malaria area regarding antimalarial prevention: a prospective study R. Voumard* (St-Blaise, Switzerland), D. Berthod, V. D'Acremont, B. Genton Posters O096 HALL H Chairs, Speakers & Authors ORAL SESSION: Microbiome and microbiota: new M’s in microbiology 14:30 – 15:30 Exhibition HALL G 24th ECCMID / Barcelona Final Programme 47 General Information 14:30 – 15:30 Scientific Programme Sunday, 11 May 2014 14:30 – 15:30 HALL I ORAL SESSION: Different prevention strategies in immunocompromised patients Chairs: Per Ljungman (Sweden) Georg Maschmeyer (Germany) O106 14:42 Efficacy and safety of influenza vaccination during the first six months post-transplantation Á. Bulnes Ramos* (Seville, Spain), E. Cordero, T.A. Aydillo, B. Leon Jiménez, J. Torre Cisneros, R. Lara, J. Gavaldà, M. Gentil, M. Gómez Bravo, P. Pérez Romero O108 14:54 Spleen off – a prospective multi-centre case- control study on the epidemiology, microbiology and outcome of severe sepsis/septic shock after splenectomy C. Theilacker* (Freiburg, Germany), K. Ludewig, M. Bögelein, V. Bahr, A. Pohl, K. Kogelmann, S. Frieseke, R. Bogdanski, F.M. Brunkhorst, W.V. Kern O109 15:06 A computer simulation model of the cost- effectiveness of routine Staphylococcus aureus screening and decolonisation among lung and heart-lung transplant recipients C.J. Clancy* (Pittsburgh, United States), S. Bartsch, R. Shields, D. Stuckey, B. Lee, M.H. Nguyen O110 15:18 Safety and efficacy of caspofungin in prophylaxis of invasive fungal infection (IFI) in liver transplant recipients (LTR): a multi-centre study J. Fortun Abete* (Madrid, Spain), O. Len, J.M. Montejo, M. Bodro, J. Torre-Cisneros, A. Moreno, M.C. Fariñas, P. Martin-Davila, J. Gavalda, A. Muriel HALL J SYMPOSIUM: Hot topic: Ebola in Africa Chairs: TBA Laboratory response to Ebola virus infections: from the field to suspected imported cases TBC: Sylvain Baize (France) 14:30 Compliance with post-haematopoietic stem cell transplantation vaccination consensus guidelines E. Ariza-Heredia* (Houston, United States), A. Gulbis, P. Kebriaei, K. Stolar, K. McConn, V. Mulanovich, G. Viola, R. Chemaly O107 14:30 – 15:30 Clinical and epidemiological aspects with a focus on the recent epidemic in West Africa TBC: Stephane Hugonnet (Switzerland) 16:00 – 18:00 HALL A SYMPOSIUM: Improving empirical antibiotic treatment in hospital Chairs: Jesús Rodríguez-Baño (Spain) Gunnar Kahlmeter (Sweden) SY162 16:00 The contribution of rapid diagnostic techniques to current clinical practice Michel Drancourt (France) SY163 16:30 What are we trying to improve: long-term outcomes of sepsis Leonard Leibovici (Israel) SY164 17:00 Does appropriate empirical antibiotic treatment improve outcomes for infections caused by MDR bacteria? Evelina Tacconelli (Germany) SY165 17:30 Ecological use of antibiotics. Is it possible? David L. Paterson (Australia) 16:00 – 18:00 HALL D ORAL SESSION: Use of next generation sequencing in clinical practice Chairs: Jordi Vila Estape (Spain) Gilbert Greub (Switzerland) O111 16:00 Investigation of vanA Enterococcus faecium isolates associated with hospital outbreak in Copenhagen using whole genome sequencing, multi-locus sequence typing and pulsed-field gel electrophoresis M. Pinholt* (Hvidovre, Denmark), H. Larner-Svensson, L. Jacobsen, S.S. Olsen, J.B. Nielsen, P. Worning, H.T. Westh, A.M. Hammerum, The Danish Enterococcus study group 48 24th ECCMID / Barcelona Final Programme Scientific Programme Sunday, 11 May 2014 O119 resistant Staphylococcus aureus (VRSA) isolated in Europe J.A. Carrico* (Lisbon, Portugal), A. Friães, K. Prior, D. Harmsen, M. Ramirez, J. Melo-Cristino TB genomes across large data sets C. Del Ojo Elias* (Oxford, United Kingdom), J. Hedge, T. Walker, D. Wilson, D. Crook, T. Peto O120 16:24 Draft genome sequence of methicillin-resistant community-acquired methicillin-resistant Staphylococcus aureus lineage, assessed by whole genome sequencing of a time-based and geographically diverse collection M. Stegger* (Copenhagen, Denmark), T. Wirth, P.S. Andersen, R.L. Skov, A. De Grassi, P. Martins-Simoes, L.B. Price, F. Vandenesch, A.R. Larsen, F. Laurent Staphylococcus aureus (MRSA) representative of predominant MRSA sequence type 8 circulating in Moscow, Russia O. Dmitrenko, V. Gostev* (St. Petersburg, Russia), A. Kudryavtseva, M. Gracheva, S. Sidorenko 16:36 Whole genome sequenced based epidemiology 16:48 Phylogenetic analysis of Streptococcus mitis and Streptococcus oralis causing infective endocarditis based on house-keeping genes sequences extracted from whole genome sequencing L.H. Rasmussen, R. Dargis, F. Rosenvinge, C. Moser, U.S. Justesen, O. Skovgård, J.J. Christensen, X.C. Nielsen* (Slagelse, Denmark) O116 17:00 Blinded validation study of genotypic prediction of antimicrobial resistance from Staphylococcus aureus whole genome sequences N.C. Gordon* (London, United Kingdom), J. Price, K. Cole, A.M. Kearns, B. Pichon, T.E.A. Peto, D. Crook, A.S. Walker, T. Golubchik O117 O118 SYMPOSIUM: Making sense of our relationships with mucosal commensals and pathogens ICAAC Chairs: Marc Lecuit (France) Robin Patel (United States) SY166 16:00 Streptococcus pneumoniae colonisation of the human host and transmission Jeffrey N. Weiser (United States) SY167 16:30 Shigella and the gut: an inflamed debate Philippe Sansonetti (France) SY168 17:00 The specificity of Salmonella enterica Typhi for humans: uncovering cell and host restriction factors Jorge Galan (United States) SY169 17:30 Understanding Neisseria meningitidis pathogenesis to design and evaluate meningococcal vaccines Chris Tang (United Kingdom) 17:12 Evaluation of an accelerated workflow using an amplicon-based commercial kit and automated analysis of next generation sequencing results for surveillance of ESBL-producing E. coli J.W. Rossen* (Groningen, The Netherlands), J. Veenemans, G.C. Raangs, P.C. Langereis, J.A.J.W. Kluytmans, A.W. Friedrich, B. Sinha HALL E Overview & Programme O115 16:00 – 18:00 ePosters of vancomycin-resistant Enterococcus faecium during an epidemic rise in Dutch hospitals R. Willems* (Utrecht, The Netherlands), M. De Been, J. Sinnige, E. Brouwer, W. Van Schaik, J. Corander, M. Bonten Posters O114 17:48 Sub-Saharan origin of the European ST80 arranged with the ASM, American Society for Microbiology, Programme Committee of the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) 17:24 The importance of sample pre-treatment and DNA extraction methods for successful whole genome sequencing of MGIT culture for Mycobacterium diagnosis L.J. Pankhurst* (Oxford, United Kingdom), A.A. Votintseva, T.M. Walker, C. Del Ojo Elias, MMM Consortium Exhibition O113 17:36 A real-time computational method for matching Chairs, Speakers & Authors 16:12 Whole genome analysis of the first vancomycin- 24th ECCMID / Barcelona Final Programme 49 General Information O112 Scientific Programme Sunday, 11 May 2014 16:00 – 18:00 HALL H SYMPOSIUM: Ins and outs of Legionnaires Disease 16:00 – 18:00 HALL J SYMPOSIUM: Bacterial persistence and tolerance: from bench to bedside ESGLI, European Centre for Disease Control (ECDC) Chairs: Annelies Zinkernagel (Switzerland) Surbhi Malhotra-Kumar (Belgium) Chairs: Birgitta de Jong (Sweden) Ed P.F. Ijzerman (The Netherlands) SY170 16:00 Diagnosis of Legionnaires Disease SY178 tolerance Jan Michiels (Belgium) Christian Lück (Germany) SY171 16:30 Treatment of Legionnaires Disease SY179 Ed P.F. Ijzerman (The Netherlands) SY172 SY180 17:00 Clinical relevance of bacterial persistence and SY181 arranged with the ESCMID Study Group for Legionella Infections (ESGLI) and the European Centre for Disease Control (ECDC) 16:00 – 18:00 HALL I SYMPOSIUM: Infections and devices: imaging & nuclear medicine meets infectious diseases European Association of Nuclear Medicine (EANM) Chairs: Werner Zimmerli (Switzerland) Alberto Signore (Italy) SY174 16:00 Bone and prosthetic joint infections: what the infectious disease specialist needs Andrej Trampuz (Germany) SY175 16:30 Bone and prosthetic joint infections: the point of view of the nuclear medicine specialist Alberto Signore (Italy) SY176 17:00 Endocarditis: what the infectious disease specialist needs Patricia Munoz (Spain) SY177 17:30 Endocarditis: how imaging and nuclear medicine can help Francois Rouzet (France) 50 tolerance Alex Soriano (Spain) 17:30 Prevention and control of Legionnaires Disease Maria Luisa Ricci (Italy) arranged with the European Association of Nuclear Medicine (EANM) 24th ECCMID / Barcelona Final Programme 16:30 Microbiological insights into heteroresistance and persistence in Gram-negative bacteria Spyros Pournaras (Greece) 17:00 Epidemiology of travel-associated Legionnaires Disease Birgitta de Jong (Sweden) SY173 16:00 Molecular basis of bacterial persistence and 17:30 Novel strategies for eradication of persister cells Kim Lewis (United States) Scientific Programme Monday, 12 May 2014 HALL A MEET-THE-EXPERT SESSION: The management of HIV/HCV infection in the era of direct active drugs 7:45 – 8:45 MEET-THE-EXPERT SESSION: Who should and who should not receive drug treatment for Chagas disease? ESGVH ESGCP Experts: Dominique Salmon-Ceron (France) David Back (United Kingdom) arranged with the ESCMID Study Group for Viral Hepatitis (ESGVH) 7:45 – 8:45 HALL D MEET-THE-EXPERT SESSION: EUCAST questions and answers EUCAST Experts: Erika Matuschek (Sweden) Derek F.J. Brown (United Kingdom) arranged with the European Committee on Antimicrobial Susceptibility Testing (EUCAST) 7:45 – 8:45 HALL F MEET-THE-EXPERT SESSION: New nomenclature: new species – any meaning for clinical relevance? arranged with the ESCMID Study Group for Clinical Parasitology (ESGCP) 7:45 – 8:45 HALL J MEET-THE-EXPERT SESSION: Current challenges and emerging evidence of infection control and prevention measures in long-term care facilities Experts: Maria Luisa Moro (Italy) Beatrice Jans (Belgium) 9:00 – 11:00 HALL A SYMPOSIUM: What is hot in HIV in 2014? Chairs: Dan Otelea (Romania) Guido Antonelli (Italy) EFISG arranged with the ESCMID Fungal Infection Study Group (EFISG) 7:45 – 8:45 HALL H MEET-THE-EXPERT SESSION: Altered drug disposition in the elderly Martin Tolstrup (Denmark) SY189 9:30 Immunological control in HIV infection: is it achievable? Giuseppe Pantaleo (Switzerland) Posters SY188 9:00 Toward a functional HIV cure SY190 10:00 When to start HIV treatment? Anna Maria Geretti (United Kingdom) SY191 10:30 HIV therapy: what is in the pipeline in 2014? Chairs, Speakers & Authors Experts: Malcolm Richardson (United Kingdom) Yvonne Gräser (Germany) EPASG, ESGIE Experts: William Couet (France) Leonardo Pagani (Switzerland) Jose M. Gatell (Spain) arranged with the ESCMID PK/PD of AntiInfectives Study Group (EPASG) and the ESCMID Study Group for Infections in the Elderly (ESGIE) Exhibition Overview & Programme Experts: Rogelio López-Vélez (Spain) Pere Albajar (Switzerland) ePosters HALL I 24th ECCMID / Barcelona Final Programme 51 General Information 7:45 – 8:45 Scientific Programme Monday, 12 May 2014 9:00 – 11:00 HALL D SYMPOSIUM: Colistin: position in the era of multi-resistance 9:00 – 11:00 ORAL SESSION: Outbreaks of MDR Gram-negative bacteria: what works and what does not work? Chairs: Juan P. Horcajada (Spain) Helen Giamarellou (Greece) Chairs: Barry Cookson (United Kingdom) Anna-Pelagia Magiorakos (Sweden) SY192 9:00 PK/PDs and susceptibility testing: are we far from the correct direction? John D. Turnidge (Australia) O121 Robert Hancock (Canada) SY195 10:00 Efficacy issues: clinical evidence on monotherapy and combination therapies David L. Paterson (Australia) O122 patients: the Prato Consensus Roger L. Nation (Australia) HALL F SYMPOSIUM: Full laboratory automation O123 SY196 9:00 Advantages and limitations of the different full O124 O125 SY198 10:00 Microbiology modernisation and rationalisation: 9:48 Main failings of interventions aimed at minimising the hospital spread of multidrugresistant Gram-negative bacteria M.A. Cataldo, F. Foschi* (Tübingen, Germany), G. De Angelis, G. Restuccia, J. Rodriguez-Baňo, B. Cookson, E. Tacconelli a professional challenge Hilary Humphreys (Ireland) SY199 10:30 Information technology and automation: ground floor view from London Peter Wilson (United Kingdom) 9:36 Klebsiella pneumoniae in fibreoptic endoscope causes ICU-outbreak S. Jørgensen* (Lørenskog, Norway), M. Skogstad, K. Helmersen, M. Weider, A.H. Schreiner 9:30 What to take into consideration when planning to move towards full lab automation? Johan Van Eldere (Belgium) 9:24 A ventilator-focused intervention to reduce the rate of Acinetobacter baumannii infection among ventilated patients R. Cohen* (Netanya, Israel), Z. Shimoni, R. Ghara, R. Ram, R. Ben-Ami Chairs: Gerard Lina (France) Margareta Ieven (Belgium) lab automated systems for bacteriology Antony Croxatto (Switzerland) 9:12 Successful control of a nosocomial outbreak and endemicity of Acinetobacter baumannii with the implementation of a multicomponent intervention programme H.U. Virgen del Rocío (UHVR ) 2012-2013 V. Gonzalez Galan* (Seville, Spain), R. Valencia, A. Cazalla, J. Lepe, R. Alvarez, C. Martin, I. Alonso, J. Dominguez, J. Aznar, J. Cisneros SY194 10:30 Challenges of clinical trials in critically ill SY197 9:00 Outbreak of colistin-resistant carbapenemase- producing Klebsiella pneumoniae (KPC-Kp) in The Netherlands, with inter-institutional spread V. Weterings* (Breda, The Netherlands), E. Weterings, E. Verkade, D. Van Stenis, E. Thewessen, J.A.J.W. Kluytmans SY193 9:30 The polymyxin resistome 9:00 – 11:00 HALL H O126 10:00 Effects of a multimodal intervention programme on compliance with standard precautions at a German university hospital S. Wehrle, D. Luft, W. Ebner, S. Barkhausen, W.V. Kern, M. Dettenkofer* (Freiburg, Germany) 52 24th ECCMID / Barcelona Final Programme Scientific Programme Monday, 12 May 2014 10:12 Incremental value of real-time feedback to 9:00 – 11:00 healthcare workers during direct hand hygiene observations K. Hussein* (Haifa, Israel), S. Warman, Y. Cohen, G. Rabino, L. Froymovich, N. Kazman, M. Furer, T. Zuckerman, M. Paul 10:24 Timing of the emergence of the Hawthorne effect in hand hygiene surveillance: a multi-centre prospective cohort study J. Yin, H.S. Reisinger, M. Vander Weg, M.L. Schweizer, A. Jesson, D.J. Morgan, G. Forrest, L. Pineles, E.N. Perencevich* (Iowa City, IA, United States) O129 10:36 Countries- expenditure on healthcare and ESGBIS Chairs: Harald Seifert (Germany) Alvaro Pascual Hernandez (Spain) SY204 9:00 Pathogenesis of complicated SAB: pathogen, host, or both? Vance G. Fowler (United States) SY205 9:30 Complicated SAB: who we should be worried about and how to evaluate Achim Kaasch (Germany) SY206 10:00 Combined therapy versus monotherapy. hospitals- provision of alcohol-based handrub: results of the pan-European PROHIBIT survey S. Hansen* (Berlin, Germany), W. Zingg, F. Schwab, M. Behnke, D. Pittet, P. Gastmeier O130 SYMPOSIUM: Staphylococcus aureus bacteraemia: controversial issues Any news? Guy Thwaites (United Kingdom) SY207 10:30 Vancomycin MIC in MSSA and MRSA. What does it mean and does it really matter? Miquel Pujol (Spain) 10:48 Infection prevention in Dutch hospitals: rapid improvement through enforcement by healthcare inspectorate M. Langelar* (Amsterdam, The Netherlands), S. Hulsbosch, M. Bilkert-Mooiman, R. Westerhof 9:00 – 11:00 HALL I SYMPOSIUM: An update on leishmaniasis Overview & Programme O128 HALL J arranged with the ESCMID Study Group for Bloodstream Infections and Sepsis(ESGBIS) 11:30 – 12:30 HALL A KEYNOTE LECTURE: Better to prevent than to cure: case of HIV ePosters O127 Chair: Mario Poljak (Slovenia) KL208 Quarraisha Abdool Karim (South Africa) Where are the hot spots? Jorge Alvar (Switzerland) SYMPOSIUM: Molecular diagnosis: commercial or home-made tests – Pro / Con debate Chairs: Jordi Vila Estape (Spain) Marijke Raymaekers (Belgium) SY201 9:30 Infection vs disease – asymptomatic carriers and risk factors for reactivation and recurrence Caryn Bern (United States) SY202 10:00 Diagnosis: monitoring outcome SY209 11:30 Molecular diagnosis should be done using CE-marked commercial kits Margareta Ieven (Belgium) Thomas Dorlo (The Netherlands) SY203 10:30 Treatment options: evidence-based recommendations for different Leishmania spp Rogelio López-Vélez (Spain) SY210 12:00 Molecular diagnosis should be done using home-made test Gilbert Greub (Switzerland) arranged with the ESCMID Study Group for Clinical Parasitology (ESGCP) 24th ECCMID / Barcelona Final Programme 53 General Information HALL B Chairs, Speakers & Authors SY200 9:00 Global epidemiology of leishmaniasis. 11:30 – 12:30 Exhibition Chairs: Emmanuel Bottieau (Belgium) Martin P. Grobusch (The Netherlands) Posters ESGCP Scientific Programme Monday, 12 May 2014 11:30 – 12:30 HALL C KEYNOTE LECTURE: Fighting against fungal infections: cells on the front lines 11:30 – 12:30 HALL E ORAL SESSION: Enterococcal resistance EFISG Chairs: Markus Dettenkofer (Germany) Rob Willems (The Netherlands) Chair: Giuliana Lo Cascio (Italy) KL211 Emmanuel Roilides (Greece) arranged with the ESCMID Fungal Infection Study Group (EFISG) 11:30 – 12:30 O136 mechanism and clonal relatedness I. Gawryszewska* (Warsaw, Poland), D. Zabicka, W. Hryniewicz, E. Sadowy HALL D ORAL SESSION: Antivirulence drugs O137 11:30 Synergistic mechanisms of action for a novel multifunctional antibody format against Pseudomonas aeruginosa used alone or adjunctively with antibiotics A. DiGiandomenico, A.E. Keller, C. Gao, G.J. Rainey, P. Warrener, M.M. Camara, J. Bonnell, J. Hilliard, W. Zhao, K. Stover* (Gathersburg, MD, United States) O132 11:42 Carbohydrate-mediated inhibition of Bordetella O138 O139 O134 12:06 Protein aggregation as a novel antimicrobial strategy against Gram-negative bacteria L. Khodaparast* (Leuven, Belgium), L. Khodaparast, M. Shahrooei, J. Van Eldere O135 12:18 Anti-alpha toxin mAb LC10 protects from severe disease and exhibits synergy in combination with antibiotics in a murine S. aureus pneumonia model C. Tkaczyk, L. Hua, Y. Shi, J. Hilliard, L. Cheng, C.K. Stover, B.R. Sellman* (Gaithersburg, United States) 54 24th ECCMID / Barcelona Final Programme 12:06 Antibiotic resistance, copper and mercury tolerance genes are carried by RepA-N pLG1-like megaplasmids among Enterococcus from several origins and clones E. Silveira, M. Barros, A. Freitas, P. Antunes, T.M. Coque, L. Peixe, C. Novais* (Matosinhos, Portugal) 11:54 How to use FimH-antagonists in urinary tract infection treatment – evaluation of a potent FimH-antagonist A. Sigl* (Basel, Switzerland), K. Mayer, N. Lüdin, P. Frei, B. Ernst 11:54 A putative novel mechanism of resistance to quinupristin-dalfopristin in clinical isolates of Enterococcus faecium in Northern Ireland T.D. Shaw* (Belfast, United Kingdom), T. Schneiders, M. Pathiraja, R.L.R. Hill, J.S. Elborn, R. McMullan bronchiseptica adhesion to rabbit respiratory epithelium M. Patiño* (Bogotá, Colombia), C. Gallego, N.M. Martínez, C.A. Iregui O133 11:42 Increased frequency of linezolid resistance among clinical Enterococcus faecium isolates from German hospital patients G. Werner* (Wernigerode, Germany), A. Thuermer, A. Mischnik, N. Mutters, J. Bender, I. Klare Chairs: Robert A. Bonomo (United States) Fernando Baquero (Spain) O131 11:30 Linezolid-resistant enterococci – resistance O140 12:18 Mature biofilms of Enterococcus faecalis and Enterococcus faecium are highly resistant to antibiotics A. Holmberg* (Lund, Sweden), M. Rasmussen Scientific Programme Monday, 12 May 2014 HALL F ORAL SESSION: Molecular detection of resistance: dream or reality? 11:30 – 12:30 ORAL SESSION: Viral paediatric infections Chairs: Stefania Stefani (Italy) Truls Michael Leegaard (Norway) Chairs: Ron Dagan (Israel) Mark Muscat (Denmark) O146 O147 species colonisation by KPC-producing Enterobacteriaceae E. Khabra* (Tel Aviv, Israel), A. Adler, S. Paikin, Y. Carmeli O143 O144 O148 O149 11:30 – 12:30 KEYNOTE LECTURE: Community-acquired pneumonia – current challenges and future directions HALL G 12:06 Prevalence of human parechovirus central nervous system infections in children from five distinct geographical regions in the United States in 2012 R. Selvarangan* (Kansas City, United States), S. Juretschko, J. Dunn, M. Marcon, H. Salimnia, K. Estes 12:18 Transforming national reference services for S. aureus: added value of WGS for public health surveillance A. Kearns* (London, United Kingdom), M. Doumith, A. Underwood, S. Platt, R. Tewodle, L. Harwin, R. Hill, N. Woodford, R. Pike, B. Pichon 11:54 Congenital cytomegalovirus infection in Finland – a prospective cohort study L. Puhakka* (Helsinki, Finland), M. Lappalainen, T. Lönnqvist, R. Niemensivu, P. Lindahl, T. Nieminen, N. Chowdhury, S. Boppana, H. Saxen 12:06 One sixteen-minute multiplex assay for the detection of AmpCs, ESBLs, MBLs and KPCs using rapid PCR amplification C. Geyer, S. Morrow, N. Hanson* (Nebraska, United States) O145 aetiology in respiratory disease S. Rhedin, A. Lindstrand, M. Rotzén-Östlund, T. Tolfvenstam, L. Ohrmalm, M. Ryd Rinder, A. Ortqvist, B. Henriques-Normark, K. Broliden, P. Naucler* (Stockholm, Sweden) 11:54 Application of real-time PCR for the detection of macrolide resistance in Belgian M. pneumoniae strains K. Loens* (Antwerp, Belgium), S.C. Masha, K. Lagrou, H. Goossens, M. Ieven 11:42 The importance of controls in studies of viral O150 12:18 Upper respiratory tract bacteria and viruses in children presenting to primary care with acute cough and RTI: preliminary results from the 'TARGET' cohort study H. Christensen, N. Redmond, A. Lovering, B. Vipond, J. Leeming, P. Muir* (Bristol, United Kingdom), S. Turnbull, T. Peters, A. Hay, On behalf of the TARGET study team Chair: Robert C. Read (United Kingdom) KL212 Overview & Programme 11:42 The tale of two outbreaks: mono- vs. multi- ePosters O142 positivity of amplification of RNA-dependent RNA polymerase gene in laboratory diagnosis of norovirus infection F. Lin* (Taoyuan, Taiwan), Y. Shen, K. Tsao, Y. Huang, C. Chen Posters resistant Pseudomonas aeruginosa be identified based on oprD sequence? F. Paasch, C. Lammens, S. Malhotra, H. Goossens, R. Painter, D. Wisniewski, Y. Park, J. Hermes, K. Young* (Kenilworth, United States) 11:30 Incidence and factors associated with false- Chairs, Speakers & Authors 11:30 Can a molecular diagnostic for imipenem- Exhibition O141 HALL H Jordi Carratala (Spain) 24th ECCMID / Barcelona Final Programme 55 General Information 11:30 – 12:30 Scientific Programme Monday, 12 May 2014 11:30 – 12:30 HALL I SYMPOSIUM: Acute anaemia after treatment of malaria with intravenous artesunate – a new variant of blackwater fever? 14:30 – 15:30 ORAL SESSION: HIV – behaviour and beliefs Chairs: José M. Miro (Spain) Martin Tolstrup (Denmark) ESGCP Chairs: Blaise Genton (Switzerland) Clara Menendez (Spain) O166 SY213 11:30 Acute anaemia after treatment of malaria with 12:00 Haemolysis in USA patients treated with intravenous artesunate Patrick Kachur (United States) O167 11:30 – 12:30 HALL J O168 SYMPOSIUM: The year in Infectious Diseases 11:30 Part I Jean Paul Stahl (France) SY216 14:54 Combined antiretroviral treatment shows preventive effectiveness in unprotected anal or vaginal sex in serodiscordant couples J. Del Romero, I. Río, B. Baza, M. Vera, J. Castilla, V. Paredes* (Madrid, Spain), C. Rodríguez Chair: Nicola Petrosillo (Italy) SY215 14:42 HIV transmission clusters among injecting drug users from Romania S. Ruta* (Bucharest, Romania), C. Oprea, A. Temereanca, A. Rosca, C. Sultana, I. Ianache, E. Ceausu, S. Mehta arranged with the ESCMID Study Group for Clinical Parasitology (ESGCP) 14:30 HPV infection in HIV-infected men who have sex with men (MSM) S.G. Parisi* (Padua, Italy), R. Scaggiante, A. Barelli, S. Andreis, C. Boldrin, F. Dal Bello, M. Cruciani, C. Mengoli, M. Basso, G. Palù intravenous artesunate Michael Ramharter (Austria) SY214 HALL A O169 15:06 Transition to adult care: health status and treatment factors in Swiss youths living with HIV C. Kahlert, C. Rudin, J. Fehr, P. Vernazza, D. Nicca* (St. Gallen, Switzerland) 12:00 Part II Pierluigi Viale (Italy) O170 15:18 Investigating health beliefs about HIV in South Africa and the impact of the HIV and AIDS, counselling and testing (HCT) campaign M. Liyawdeen* (Edgware, United Kingdom), S. Puvaneswaran, H. Afzal, J. Anthonypillai, M. Bahra 14:30 – 15:30 HALL B SYMPOSIUM: Going away from blood: why not to test oral fluid and urine? Chairs: Mario Poljak (Slovenia) Gilbert Greub (Switzerland) SY217 14:30 Oral fluid testing in microbiology Nitika Pant Pai (Canada) SY218 15:00 Urine testing in microbiology Katja Seme (Slovenia) 56 24th ECCMID / Barcelona Final Programme Scientific Programme Monday, 12 May 2014 HALL C KEYNOTE LECTURE: Excellence Award Lecture: Close encounters of the third kind – pathogens and globalisation 14:30 – 15:30 SYMPOSIUM: T-cells in invasive aspergillosis EFISG Chairs: Anne Puel (France) Maiken Cavling Arendrup (Denmark) Chair: Giuseppe Cornaglia (Italy) Ilaria Capua (Italy) Chairs: Joseph S. Solomkin (United States) Sibel Ascioglu (Turkey) O151 14:30 Early clinical improvement and clinical cure in a randomised controlled phase 3 study of ceftobiprole versus ceftazidime/linezolid in patients with hospital-acquired pneumonia T. Scheeren* (Groningen, The Netherlands), A. Rodriguez, X. Zhou, M. Saulay, M. Engelhardt SY221 15:00 Therapy Thomas Lehrnbecher (Germany) arranged with the ESCMID Fungal Infection Study Group (EFISG) 14:30 – 15:30 KEYNOTE LECTURE: The effects of antibiotic pollution on the environmental resistance gene reservoir Chair: Peter M. Hawkey (United Kingdom) KL222 O152 14:42 A single dose of oritavancin (ORI) compared to 7-10 days of vancomycin (VAN): clinical response across different lesion types in the SOLO noninferiority studies G.R. Corey* (Durham, United States), H. Jiang, S. Good, G. Moeck, M. Wikler O153 O154 O155 15:18 Ceftaroline fosamil 600mg every 12 hours is superior to ceftriaxone 2g every 24 hours for Asian patients hospitalised with communityacquired pneumonia (CAP): a randomised trial N. Zhong, T. Sun, G. D'Souza, S.H. Lee, H.L. Nguyen, C.-H. Chiang, D. Wilson, F. Sun, D. Melnick* (Wilmington, United States) HALL G ORAL SESSION: Detection of broad-spectrum beta-lactamases Chairs: Laurent Poirel (Switzerland) Christina Vandenbroucke-Grauls (The Netherlands) O156 14:30 Bloodstream infections caused by Pseudomonas spp.; how to detect carbapenemase producers rapidly? L. Dortet, L. Poirel, P. Nordmann* (St. Gallen, Switzerland) 15:06 Comparison of the microbiological efficacy of tedizolid and linezolid in the Establish-1 and Establish-2 phase 3 clinical trials C. De Anda* (San Diego, United States), E. Fang, A. Das, P. Prokocimer Joakim Larsson (Sweden) 14:30 – 15:30 14:54 Telavancin for acute bacterial skin and skin structure infections (ABSSSI) – a retrospective analysis of the phase 3 ATLAS trials considering the 2013 FDA guidance S.L. Barriere* (San Francisco, United States), W. Wang, M.E. Stryjewski, G.R. Corey HALL F Overview & Programme ORAL SESSION: New antibiotics in clinical trials Bart Jan Kullberg (The Netherlands) ePosters HALL D O157 14:42 Species-dependent performance of a selective screening method for extended-spectrum betalactamase producing Enterobacteriaceae in hospitalised patients M. Kluytmans - van den Bergh* (Breda, The Netherlands), C. Verhulst, C. Verduin, C. Vandenbroucke-Grauls, M. Bonten, J.A.J.W. Kluytmans, A.W. Friedrich, SoM study group 24th ECCMID / Barcelona Final Programme 57 Posters 14:30 – 15:30 SY220 14:30 Pathogenicity Chairs, Speakers & Authors Exhibition KL219 HALL E General Information 14:30 – 15:30 Scientific Programme Monday, 12 May 2014 O158 14:54 Comparison of several combination disk tests O164 15:06 Clinical evaluation of a fully automated PCR for the detection of metallo-beta-lactamaseproducing Pseudomonas aeruginosa A. Heinrichs* (Brussels, Belgium), T.D. Huang, C. Berhin, P. Bogaerts, Y. Glupczynski O159 15:06 Development and analysis of assays for the detection of carbapenemases in Enterobacteriaceae F.J. Hamilton* (Edinburgh, United Kingdom), R. Crispin, D. Coyle, L. Mulhern, A.P. Gibb, K.O. Helgason, E.C. Class, K.E. Templeton O160 assay for the detection of CMV-DNA in plasma of immunosuppressed patients receiving solid organ and bone marrow transplantation G. Gregori, M.G. Milia, T. Allice, A. Proietti, C. Costa* (Turin, Italy), S. Mantovani, F. Sidoti, R. Cavallo, V. Ghisetti O165 15:18 Detection of herpes simplex virus 1 and 2, and varicella zoster virus using the Quidel® molecular HSV 1+2/VZV assay on three real time PCR platforms B.W. Buchan* (Milwaukee, United States), J. Connolly, W.J. Olson, N.A. Ledeboer 15:18 Sensitivity of the modified Hodge test performed with ertapenem and meropenem for detection of carbapenemases in 942 samples of carbapenemresistant Enterobacteriaceae (CRE) F. Tuon, L. Arend, M. Pilonetto, C. Siebra, P. Arruda* (Ponta Grossa, Brazil) 14:30 – 15:30 HALL I SYMPOSIUM: Diagnostic tools in parasitology ESGCP 14:30 – 15:30 HALL H ORAL SESSION: Viral diagnostics in the immunocompromised Chairs: Laurent Kaiser (Switzerland) Pilar Perez-Romero (Spain) O161 14:42 Molecular diagnosis of central nervous system infections using PCR coupled to electrosprayionization mass spectrometry analysis of CSF samples L. Andreoletti* (Reims, France), N. Leveque, J. Legoff, C. Mengelle, Y. Nguyen, F. Renois, F. Simon, J. Izopet O163 14:54 Exhaustive monitoring of persistent viral infections after allogeneic haematopoietic stem cell transplantation using broad-range PCR combined with electrospray-ionization mass spectrometry M. Salmona* (Paris, France), F. Sicre De Fontbrune, S. Mercier-Delarue, R. Peffault De Latour, G. Socie, F. Simon, J. Legoff 58 SY223 14:30 Advantages of mass spectrometry over microscopy Renaud Piarroux (France) SY224 15:00 Benefits of PCR and microscopy, and its combinations, in Diagnostic Parasitology Tom van Gool (The Netherlands) 14:30 The use of PCR coupled with mass spectrometry analysis for the diagnosis of viral infections in plasma samples of immunosuppressed patients C. Mengelle* (Toulouse, France), J. Le-Goff, S. Mercier-Delarue, K. Sauné, J.-M. Mansuy, F. Simon, J. Izopet O162 Chairs: Titia M. Kortbeek (The Netherlands) Martin P. Grobusch (The Netherlands) 24th ECCMID / Barcelona Final Programme arranged with the ESCMID Study Group for Clinical Parasitology (ESGCP) 14:30 – 15:30 HALL J KEYNOTE LECTURE: On the cutting edge of infection control research: what to do when evidence is missing? Chair: Evelina Tacconelli (Germany) KL225 Leonard A. Mermel (United States) Scientific Programme Monday, 12 May 2014 HALL A O174 Staphylococcus aureus and methicillin-resistant S. aureus bacteraemia in southern latitudes among 104 United States (US) hospitals: retrospective cohort study E. Perencevich* (Iowa City, IA, United States), J. Yin, M. Goto, M. Ohl, M. Schweizer, M. Carrel SYMPOSIUM: Cryptococcal infections in HIV-infected patients: what is new in 2014? EFISG, EACS Chairs: José M. Miro (Spain) Anton Pozniak (United Kingdom) O175 bacteraemia over 5 years in Italy M. Monaco* (Rome, Italy), F. Mancini, M. Del Grosso, R. Camilli, A. Sanchini, A. Pantosti O176 air ventilation system-associated transmission routes P.J. Van Duijn* (Utrecht, The Netherlands), W. Bras, L. De Graaf-Miltenburg, J. Dokter, A. Troelstra, M.J.M. Bonten SY228 17:00 Advances in antifungal therapy of cryptococcal infections Olivier Lortholary (France) SY229 17:30 Antiretroviral therapy of patients with AIDSO177 only a minority of apparent acquisitions of Staphylococcus aureus can be explained by transmission from other patients, healthcare workers or the environment J.R. Price* (Brighton, United Kingdom), T. Golubchik, K. Cole, A. Bexley, D.J. Wilson, D.W. Crook, A.S. Walker, T.E.A. Peto, J. Paul, M.J. Llewelyn arranged with the ESCMID Fungal Infection Study Group (EFISG) and the European AIDS Clinical Society (EACS) 16:00 – 18:00 HALL D ORAL SESSION: New transmission routes and genotypic diversity: are we looking at a new MRSA? O178 16:00 Surveillance of Staphylococcus aureus colonisation in a remote African pygmy population from 2009 to 2013 F. Schaumburg* (Münster, Germany), A. Alabi, M.P. Grobusch, R. Köck, A. Mellmann, P.G. Kremsner, G. Peters, K. Becker O172 16:12 Intercontinental travel and import of Staphylococcus aureus into Europe: the StaphTrav network D. Nurjadi* (Heidelberg, Germany), P. Zanger O173 16:24 MRSA in Portuguese-speaking African countries: the missing data to fill the world map T. Conceição, C. Coelho, I. Santos-Silva, H. De Lencastre, M. Aires de Sousa* (Lisbon, Portugal) 17:24 Perioperative nasal mupirocin ointment and chlorhexidine body wash prevent superficial surgical site infections in cardiac surgery P. Kohler* (Zurich, Switzerland), S. Kuster, F. Schönrath, E. Ajdler-Schäffler, A. Anagnostopoulos, S. Tschirky, V. Falk, H. Sax Chairs: Stephan J. Harbarth (Switzerland) Benito Almirante (Spain) O171 17:12 Whole-genome sequencing shows that ePosters associated cryptococcosis: when to start and what to start with David R. Boulware (United States) 17:00 MRSA outbreak in a Dutch burn centre: role of O179 Posters and cryptococcal-IRIS Robert L. Colebunders (Belgium) 17:36 Emergence of EMRSA-15 as a significant cause of S. aureus bacteraemia in Israel A. Rokney* (Jerusalem, Israel), E. Anuka, O. Barzilay, J. Moran-Gilad, V. Agmon, L. Valinsky O180 Overview & Programme SY227 16:30 Clinical manifestations of cryptococcal disease 17:48 Genotypic diversity of methicillin-resistant Staphylococcus aureus (MRSA) strains colonising and infecting patients in a large multinational prospective cohort study P. Francois, G. De Angelis, W. Schroeder* (Tübingen, Germany), G. Restuccia, E.J. Bonetti, J. Schrenzel, E. Tacconelli 24th ECCMID / Barcelona Final Programme 59 Chairs, Speakers & Authors Cryptococcus spp. in HIV-infected patients Manuel Cuenca-Estrella (Spain) 16:48 Changes in Staphylococcus aureus clones from Exhibition SY226 16:00 Epidemiology and microbiology of 16:36 Higher incidence of community-associated General Information 16:00 – 18:00 Scientific Programme Monday, 12 May 2014 16:00 – 18:00 HALL E SYMPOSIUM: Predicting the future in fungal diagnosis and therapy Chairs: Peter G. Pappas (United States) Andrew J. Ullmann (Germany) ESGCD Chairs: Ed J. Kuijper (The Netherlands) Franz Allerberger (Austria) SY230 16:00 Non-cultural methods for aspergillosis SY238 16:00 What is the protective factor of the microbiota? Kieren Marr (United States) Trevor Lawley (United Kingdom) 16:30 Candidal diagnostic tests SY239 16:30 Does antimicrobial stewardship and specific Maurizio Sanguinetti (Italy) Clostridium difficile antimicrobial prophylaxis prevent CDI? Oliver A. Cornely (Germany) SY232 17:00 New cryptococcal and histoplasmosis tests George R. Thompson III (United States) SY233 17:30 Designing new diagnostic-driven therapy SY240 17:00 What is the role of asymptomatic patients and concepts Johan Maertens (Belgium) other reservoirs in acquisition of CDI? Derrick Crook (United Kingdom) arranged with the ESCMID Fungal Infection Study Group (EFISG) and the Mycoses Study Group of the International Society for Human and Animal Mycology (MSG) 16:00 – 18:00 SY241 Future ESCMID study group on forensic microbiology (Amparo Fern·ndez-RodrÌguez, Veroniek Saegeman) Chairs: Katja Seme (Slovenia) Emmi Andersson (Sweden) Chairs: Dianelys Quinones (Cuba) Antony Croxatto (Switzerland) O181 SY236 17:00 Sudden unexpected death in infancy and O182 archival clinical samples Mario Poljak (Slovenia) 24th ECCMID / Barcelona Final Programme 16:12 Usefulness of a microbiological diagnostic protocol in a cohort of adult patients with meningoencephalitis – proposal for a stepwise algorithm C. López Sánchez* (Barcelona, Spain), E. Sulleiro, C. Bocanegra, S. Romero, I. Sanz, M.T. Tórtola, C. Pigrau, G. Codina, A. Pahissa, V. Falcó SY237 17:30 Looking for microbes in paraffin blocks and other 60 16:00 Biomarker patterns in cerebrospinal fluid (CSF) from patients evaluated for neuroborreliosis (NB) D. Nyman* (Jomala Åland, Finland), S.A. Carlsson, C. Nyberg, C. Jansson transplantation: practical guidelines Veroniek Saegeman (Belgium) arranged with the future ESCMID study group on forensic microbiology (Amparo Fernández-Rodríguez, Veroniek Saegeman) HALL I ORAL SESSION: Non-molecular diagnosis of central nervous system and bloodstream infections SY235 16:30 Microbiological testing of tissues and cells for childhood: how frequent is infectious etiology? Marta Cohen (United Kingdom) arranged with the ESCMID Study Group for Clostridium difficile (ESGCD) 16:00 – 18:00 SY234 16:00 Forensic and autopsy microbiology: general overview and current challenges Amparo Fernández-Rodríguez (Spain) 17:30 How to eradicate Clostridium difficile spores from the environment? Frédéric Barbut (France) HALL G SYMPOSIUM: Forensic and post-mortem microbiology in the 21st century HALL H SYMPOSIUM: New approaches to prevent transmission of Clostridium difficile infections EFISG, MSG SY231 16:00 – 18:00 O183 16:24 Rapid detection of pathogenic microorganisms in blood and fluids using the multiplex PCR ready-touse FilmArray® Blood Culture (FABC) assay R. Amarsy-Guerle* (Paris, France), F. Mougari, H. Jacquier, J. Riahi, L. Raskine, B. Berçot, E. Cambau Scientific Programme Monday, 12 May 2014 O184 16:36 Comparison of the BACTEC™ blood culture system with conventional culture of cerebrospinal fluid samples A. Calderaro* (Parma, Italy), M. Martinelli, F. Motta, S. Montecchini, C. Gorrini, S. Larini, M.C. Arcangeletti, F. De Conto, C. Chezzi, M.C. Medici O185 16:48 Selection of blood culture media matters – antibiotic prescribing and de-escalation are influenced by recovery rate differences between blood culture media R. Zadroga* (Minneapolis, United States), D.N. Williams, M. Kuskowski, G.T. Hansen 17:00 One-hour bacterial identification, resistance O187 Overview & Programme and virulence profiling by electrospray mass spectrometry from cultured isolates and blood culture samples O. Dauwalder* (Bron, France), Y. Charretier, C. Franceschi, E. Degout-Charmette, G. Zambardi, T. Cecchini, M. Bes, G. Durand, F. Vandenesch, J.P. Charrier 17:12 Identification of microorganisms with FilmArray® O188 ePosters directly from blood culture bottles prior to positivity M. Almuhayawi, O. Altun, K. Strålin, V. Ozenci* (Stockholm, Sweden) 17:24 Highly accurate MALDI-TOF identification using O189 Posters the VITEK® MS plus system when challenged with intentional mixtures prepared from bacteria and yeast colonies B.M. Willey* (Toronto, Canada), E. Ramoutar, P. Lo, S.M. Poutanen 17:36 Neonatal percutaneously inserted silicone 17:48 The performance of four different anaerobic blood culture bottles in detection of anaerobic bacteria and direct identification by MALDI-TOF MS M. Almuhayawi, A. Abdulmajeed, O. Altun, E. Tideholm, M. Ullberg, V. Ozenci* (Stockholm, Sweden) Exhibition O190 Chairs, Speakers & Authors catheters must be sectioned to detect its colonisation P. Martin-Rabadan* (Madrid, Spain), F. Perez-Garcia, H.S. Nisa, M. Guembe, E. Bouza 24th ECCMID / Barcelona Final Programme 61 General Information O186 ESCMID Conference on Reviving Old Antibiotics Vienna, Austria 22 – 24 October 2014 Organising Committee Rafael Canton, Madrid, ES Christian Giske, Stockholm, SE Gunnar Kahlmeter, Växjö, SE Alasdair MacGowan, Bristol, UK Johan Mouton, Nijmegen, NL Roger Nation, Melbourne, AU Mical Paul, Tel Aviv, IL Ursula Theuretzbacher, Vienna, AT John Turnidge, Adelaide, AU Françoise Van Bambeke, Brussels, BE Contact: [email protected] Find more information and registration information on our website www.escmid.org/vienna2014 Including: • Optimisation of therapy – General principles • Optimisation of therapy in Gram-negative infections • Individualisation of therapy • Extending the life of old antibiotics • Clinical trials • Breakpoints and susceptibility testing • Communicating new knowledge to where it is needed • Solved and unsolved problems with old antibiotics, identify need for action Scientific Programme Tuesday, 13 May 2014 7:45 – 8:45 HALL B MEET-THE-EXPERT SESSION: How to use next generation sequencing in future virology Experts: Marc Eloit (France) Maria Rosaria Capobianchi (Italy) 7:45 – 8:45 HALL C MEET-THE-EXPERT SESSION: Control of vancomycin-resistant enterococci: efforts justified? 7:45 – 8:45 HALL F MEET-THE-EXPERT SESSION: Strategies for malaria prevention, why do national guidelines differ? ESGCP Experts: Peter Chiodini (United Kingdom) Blaise Genton (Switzerland) arranged with the ESCMID Study Group for Clinical Parasitology (ESGCP) 7:45 – 8:45 HALL G ESGNI Experts: Markus Dettenkofer (Germany) Luisa M. V. Peixe (Portugal) MEET-THE-EXPERT SESSION: Healthcare providers and influenza vaccination EVASG arranged with the ESCMID Study Group for Nosocomial Infections (ESGNI) 7:45 – 8:45 MEET-THE-EXPERT SESSION: Management and troubleshooting of in-house molecular diagnostics in the microbiological lab ESGMYC Experts: Erik C. Böttger (Switzerland) Christoph Lange (Germany) arranged with the ESCMID Study Group for Molecular Diagnostics (ESGMD) 7:45 – 8:45 HALL I MEET-THE-EXPERT SESSION: How to treat MDR tuberculosis? ESGMD arranged with the ESCMID Vaccine Study Group (EVASG) 7:45 – 8:45 Experts: Jacob Moran-Gilad (Israel) Marijke Raymaekers (Belgium) HALL D Overview & Programme HALL E ePosters Experts: Susanna Esposito (Italy) Timo Vesikari (Finland) arranged with the ESCMID Study Group for Mycobacterial Infections (ESGMYC) Posters MEET-THE-EXPERT SESSION: Antimicrobial resistance research, supported by funding from the EU and the US NIH/NIAID European Commission, United States National Institute of Allergy and Infectious Diseases (US NIAID) arranged with the European Commission, United States National Institute of Allergy and Infectious Diseases (US NIAID) Exhibition 24th ECCMID / Barcelona Final Programme 63 General Information Chairs, Speakers & Authors Experts: Arjon Van Hengel (Belgium) Dennis M. Dixon (United States) Scientific Programme Tuesday, 13 May 2014 9:00 – 11:00 HALL A CLINICAL GRAND ROUND: Clinical Grand Round 2014 9:00 – 11:00 HALL B SYMPOSIUM: The challenge of respiratory viruses IDSA Chairs: Emmi Andersson (Sweden) TBD Chairs: Robert C. Read (United Kingdom) Jeronimo Pachon-Diaz (Spain) Experts: Nicholas J. Beeching (United Kingdom) Ajit P. Limaye (United States) Mario U. Mondelli (Italy) David L. Paterson (Australia) Adriana Vince (Croatia) SY256 9:00 Diagnostic challenges: speed, loads and multiplex Fausto Baldanti (Italy) SY257 9:30 Emerging respiratory viruses Ron A.M. Fouchier (The Netherlands) SY258 10:00 Vaccination and treatment Seven cases will be presented to experienced professors of infectious disease, who will then discuss the differential diagnosis and management plan. All cases have been carefully selected for their instructive qualities and topicality, and will be presented by fellows from major infectious disease centres in Europe and beyond. Case presenters: Alex Cochrane (United Kingdom) Julia Fischer (Germany) Angela Martinez (Spain) Nélia Neves (Portugal) Zaira Palacios Baena (Spain) Anat Stern (Israel) Sara Tedeschi (Italy) arranged with the Infectious Diseases Society of America (IDSA) Alexander C. Schmidt (Belgium) SY259 10:30 Infection control of respiratory viruses: global and local Andreas F. Widmer (Switzerland) 9:00 – 11:00 HALL C SYMPOSIUM: What is new in immunocompromised patients? ICHS Chairs: Georg Maschmeyer (Germany) Jose M. Aguado Garcia (Spain) SY260 9:00 Innate immunity and infections in transplant patients – new insights Jose M. Aguado Garcia (Spain) SY261 9:30 CMV infections: new options for clinical management Per Ljungman (Sweden) SY262 10:00 Clinical relevance of respiratory viruses in immunocompromised patients Hans H. Hirsch (Switzerland) SY263 10:30 Emerging bacterial resistance and its impact on therapy in cancer patients Claudio Viscoli (Italy) 64 24th ECCMID / Barcelona Final Programme arranged with the International Immunocompromised Host Society (ICHS) Scientific Programme Tuesday, 13 May 2014 HALL D SYMPOSIUM: Nebulised antibiotics: challenge for 2014 9:00 – 11:00 ORAL SESSION: Healthcare-associated infections – from analysis to interventions ESGCIP Chairs: Joan Gavaldà (Spain) William Couet (France) Chairs: Susan S. Huang (United States) Khetam Hussein (Israel) SY264 9:00 Nebulisers and technique of administration O191 cohort study of bacteraemia due to ESBL and carbapenemase-producing Enterobacteriaceae: the Increment project B. Gutierrez* (Seville, Spain), S. Pérez-Cortés, E. Salamanca, R.A. Bonomo, Y. Carmeli, D. Paterson, A. Pascual, J. Rodríguez-Baño nebulised antimicrobials Alasdair P. MacGowan (United Kingdom) SY266 10:00 Nebulised antibiotics for mechanically- O192 SY267 10:30 Nebulised antibiotics in cystic fibrosis and multiresistant bacteria in European hospitals: a multi-centre retrospective cohort study A. Stewardson* (Geneva, Switzerland), A. Allignol, S. Harbarth, On behalf of the TIMBER study group brochiectasis Tobias Welte (Germany) arranged with the ESCMID Study Group for Critically Ill Patients (ESGCIP) 9:00 – 11:00 9:12 The burden of bloodstream infections caused by O193 9:24 Multi-drug resistance is an important risk factor for inappropriate empiric therapy among ICU patients with Gram-negative sepsis: a cohort study M. Zilberberg* (Goshen, MA, United States), A.F. Shorr, S.T. Micek, M. Kollef HALL E SYMPOSIUM: Combined antimicrobial therapy for multi-resistant Gram-negative bacteria ESGARS O194 multi-resistant Gram-negative bacteria Mical Paul (Israel) SY269 9:30 Combined therapy for carbapenemase-producing O195 O196 arranged with the ESCMID Study Group for Antimicrobial Resistance Surveillance (ESGARS) 10:00 A multi-centre surveillance of ventilator- associated events in China Z. Zong* (Chengdu, China), S. Zhu Acinetobacter baumannii Po-Ren Hsueh (Taiwan) Chairs, Speakers & Authors Pseudomonas aeruginosa Robert A. Bonomo (United States) 10:30 Combined therapy for carbapenemase-producing 9:48 Effect of standardised surveillance of intensive care unit-acquired infections on ventilatorassociated pneumonia incidence T. Bénet* (Lyon, France), R. Ecochard, N. Voirin, A. Machut, A. Lepape, A. Savey, P. Vanhems SY270 10:00 Combined therapy for carbapenemase-producing SY271 Posters surveillance of hospital-acquired infections yielding serial weekly point-prevalence scores R. Streefkerk, G. Borsboom, C. Van der Hoeven, R. Verkooijen* (Rotterdam, The Netherlands), H. Verbrugh SY268 9:00 Aminoglycosides used in combined treatment for Klebsiella pneumoniae Mario Tumbarello (Italy) 9:36 Evaluation of an algorithm for electronic O197 Exhibition Chairs: Achilleas Gikas (Greece) Leonard Leibovici (Israel) Overview & Programme SY265 9:30 Pharmacokinetics and pharmacodynamics of ventilated patients Jean-Jacques Rouby (France) 9:00 Design and analysis feasibility of an international ePosters Jean Chastre (France) HALL F 10:12 Implementation of national guidelines for the prevention of healthcare-associated infections: results of the pan-European PROHIBIT survey S. Hansen* (Berlin, Germany), W. Zingg, F. Schwab, M. Behnke, D. Pittet, P. Gastmeier 24th ECCMID / Barcelona Final Programme 65 General Information 9:00 – 11:00 Scientific Programme Tuesday, 13 May 2014 O198 10:24 The PROHIBIT (preventing hospital-acquired infections by intervention and training) intervention trial – results of a clusterrandomised European multi-centre study on the reduction of central line-related bloodstream infections T. Van Der Kooi* (Bilthoven, The Netherlands), M. Wolkewitz, B. Van Benthem, S. De Greeff, H. Grundmann, W. Zingg on behalf of the PROHIBIT study group O199 O204 blood culture bottles using automated multiplex real-time PCR panel X. Zheng* (Chicago, United States), W. Polanco, D. Carter, S. Shulman O205 O206 10:48 The effects of decontamination of the oropharynx O208 HALL G Chairs: James Wai-Kuo Shih (China) Carlos Rodrigo (Spain) 9:00 Benefits of a costly and work intensive O209 microbiological surveillance in a cohort of very low birth weight infants (VLBWI, <1500g) W. Lindner* (Ulm, Germany), A. Essig, H. Hummler, H. Von Baum O202 O203 9:24 Microbiota profiling in children with functional constipation T.G.J. De Meij* (Amsterdam, The Netherlands), E.F.J. De Groot, M.A. Benninga, A.E. Budding, P.H.M. Savelkoul 66 24th ECCMID / Barcelona Final Programme 10:36 Carbapenem-resistant Klebsiella pneumoniae in European children: experience from EARS-Net 2011/2012 J. Bielicki* (London, United Kingdom), L. Diaz Högberg, O. Heuer, M. Sharland, EARS-Net Participants 9:12 Postoperative mediastinitis: experience of a single paediatric centre of cardiac surgery F.I. Calò Carducci* (Rome, Italy), L. Gramatica, E. Ferretti, P. Bernaschi, M. Carletti, M.L. Ciofi Degli Atti, R. Netto, A. Carotti, G. Pongiglione, P. D'Argenio 10:24 Impact of infectious diseases consultation on the management of S. aureus bacteraemia in children R.B. Saunderson, T. Gouliouris* (Cambridge, United Kingdom), E.J. Cartwright, E.J. Nickerson, S.H. Aliyu, D.R. O’Donnell, W. Kelsall, S.J. Peacock, M.E. Torok ORAL SESSION: Bacterial paediatric infections O201 10:12 Staphylococcus capitis in nosocomial bacteraemia in intensive care neonates: worldwide distribution of an endemic methicillin-resistant clone (NRCS-A) P. Martins Simões, M. Butin, S. Lemriss, J.-C. Picaud, A. Kearns, O. Denis, R. Goering, F. Vandenesch, J.-P. Rasigade, F. Laurent* (Lyon, France) and intestinal tract on antibiotic resistance in ICUs: a cluster-randomised cross-over trial E.A.N. Oostdijk* (Utrecht, The Netherlands), J. Kesecioglu, A. De Smet, M.J.M. Bonten, N.A. On behalf of the SDD-SOD study group 9:00 – 11:00 10:00 Noninvasive pneumococcal serotypes in hospitalised children in Moscow (Russia) N. Mayanskiy* (Moscow, Russia), N. Alyabieva, A. Lazareva, O. Ponomarenko, L. Katosova, A. Ivanenko, M. Lazareva, T. Kulichenko, L. Namazova-Baranova O207 O200 9:48 Serotyping of S. pneumoniae strains isolated from blood cultures of paediatric population over the last decade G. Chronopoulou* (Athens, Greece), G. Kavarnou, E. Katzilierakis, V. Syriopoulou, K. Agrafioti 10:36 Prior digestive colonisation with extended- spectrum beta-lactamase producing Enterobacteriaceae in intensive care unit: significance in patients with ventilatorassociated pneumonia R. Bruyere, C. Vigneron, A. Pechinot, J. Bador, J.P. Quenot, S. Prin, S. Aho, P.E. Charles* (Dijon, France) 9:36 Rapid pathogen identification from paediatric O210 10:48 Measurement of sCD14 – presepsin is a good alternative to monitor children after external ventricular drainage (EVD) in case of suspected bacterial ventriculitis/meningitis M. Skvarc* (Ljubljana, Slovenia), D. Stubljar, M. Groselj Grenc, A. Kopitar Scientific Programme Tuesday, 13 May 2014 HALL H SYMPOSIUM: PK/PD – the merits of models and measurement 9:00 – 11:00 SYMPOSIUM: Optimisation of empirical and targeted antifungal therapy for invasive aspergillosis EPASG Chairs: William A. Craig (United States) Paul M. Tulkens (Belgium) Chairs: Kieren Marr (United States) Catherine Cordonnier (France) SY272 9:00 Pre-clinical in vitro models SY280 9:00 Persistent febrile neutropenia: diagnostic- Karen E. Bowker (United Kingdom) driven antifungal therapy vs. empirical antifungal therapy Manuela Aguilar-Guisado (Spain) SY273 9:30 Pre-clinical in vivo models Niels Frimodt-Moller (Denmark) 10:00 Measurement of beta-lactams in serum SY281 9:30 Therapeutic monitoring of drug levels for invasive aspergillosis Susan J. Howard (United Kingdom) Federico Pea (Italy) 10:30 Value of the measurement of antibiotic SY282 10:00 First-line therapy with combined antifungal for concentration in tissues Johan W. Mouton (The Netherlands) SY283 10:30 Salvage therapy of invasive aspergillosis refractory to primary therapy with voriconazole Johan Maertens (Belgium) HALL I SYMPOSIUM: The hidden Beijing M. tuberculosis pandemic Chairs: Julian Gonzalez-Martin (Spain) Christoph Lange (Germany) 11:30 – 12:30 SYMPOSIUM: The year in Clinical Microbiology Chair: Robert L. Skov (Denmark) SY276 9:30 Rapid detection and infective and clonal behaviours in the Beijing lineage Dario Garcia de Viedma (Spain) SY277 9:00 Resistance of Beijing tuberculosis Sonia Borrell (Switzerland) SY284 11:30 Part I Emmanuelle Cambau (France) SY285 12:00 Part II Miquel Bart Ekkelenkamp (The Netherlands) SY278 10:00 Treatment and hospital management of contagious multiresistant Beijing tuberculosis pulmonary infection Keertan Dheda (South Africa) SY279 10:30 Selective advantages of the Beijing genotype of Mycobacterium tuberculosis Dick van Soolingen (The Netherlands) HALL A ePosters 9:00 – 11:00 Overview & Programme arranged with the ESCMID PK/PD of AntiInfectives Study Group (EPASG) Posters aspergillosis Raoul Herbrecht (France) 11:30 – 12:30 HALL B KEYNOTE LECTURE: Cross-neutralising antibodies for respiratory virus therapy and vaccine design Chair: Joan Gavaldà (Spain) KL286 Chairs, Speakers & Authors SY275 Davide Corti (Switzerland) Exhibition SY274 HALL J 24th ECCMID / Barcelona Final Programme 67 General Information 9:00 – 11:00 Scientific Programme Tuesday, 13 May 2014 11:30 – 12:30 HALL C SYMPOSIUM: Surveillance of healthcare-associated infections: infections or procedures? 11:30 – 12:30 HALL D ORAL SESSION: Advances in CMV infection in transplant recipients Chairs: Claudio Viscoli (Italy) Per Ljungman (Sweden) Chairs: Hanan Balkhy (Saudi Arabia) Khetam Hussein (Israel) O211 SY287 11:30 Infections 11:30 Cytomegalovirus specific T-cell immune response as a risk factor of infection in solid organ transplant recipients at low risk for CMV infection D. Mena Romo* (Seville, Spain), P. Pérez-Romero, C. Martín-Gandul, P. Blanco-Lobo, M. Sánchez, M. Gentil, M. Gómez, E. Lage, E. Cordero Petra Gastmeier (Germany) SY288 12:00 Procedures Jesús Rodríguez-Baño (Spain) O212 11:42 Reconstitution of CMV-specific immunity post heart transplantation may guide customisation of immunosuppressive and antiviral strategies: a prospective randomised study T. Lazzarotto* (Bologna, Italy), A. Chiereghin, G. Bianchi, G. Piccirilli, B. Perciaccante, L. Borgese, G. Magnani, F. Grigioni, M.P. Landini, L. Potena O213 11:54 CMV- and EBV-specific immune recovery in lung transplant recipients is not associated with protection from infection A. Saldan, D. Tinto, F. Franceschi, M. Loy, F. Rea, C. Mengoli, D. Sgarabotto, G. Palu, D. Abate* (Padua, Italy) O214 12:06 Effectiveness of early-onset vs delayed-onset universal cytomegalovirus (CMV) prophylaxis in D+/R- solid organ transplant (SOT) recipients: importance of cytomegalovirus (CMV)-specific T-cell response R. San Juan Garrido* (Madrid, Spain), D. Navarro, A. Garcia-Reyne, M. Montejo, P. Muñoz, J. Carratala, O. Len, J. Fortun, B. Muñoz-Cobo, J. Aguado O215 12:18 Delayed-onset cytomegalovirus coded during hospital readmission in a retrospective cohort of liver transplant recipients in the United States C.A.Q. Santos* (St. Louis, United States), D.C. Brennan, W.C. Chapman, V.J. Fraser, M.A. Olsen 68 24th ECCMID / Barcelona Final Programme Scientific Programme Tuesday, 13 May 2014 11:30 – 12:30 HALL E O220 12:18 Genotyping supports the clinical significance of isolation of Aspergillus fumigatus from sputum and bronchial secretion samples for the diagnosis of invasive pulmonary aspergillosis P. Escribano, T. Peláez, P. Muñoz, B. Padilla, E. Bouza, J. Guinea Ortega* (Madrid, Spain) SYMPOSIUM: Young Investigator Award Lectures Chair: Murat Akova (Turkey) SY289 11:30 Gut-lung axis: the intestinal microbiota in pneumonia W. Joost Wiersinga (The Netherlands) 11:30 – 12:30 SY290 12:00 Development of antimalarial drugs in HALL H SYMPOSIUM: Can we treat Gram-negative bacteraemia with a short-course of antibiotics? Pro / Con debate Lambaréné, Gabon Michael Ramharter (Austria) Chairs: Jean Chastre (France) Harald Seifert (Germany) Aspergillus fumigatus and its resistance pattern by real-time PCR G. Gaajetaan, G. Dingemans, W. Van de Sande, B. Rijnders* (Rotterdam, The Netherlands), M.P. Hayette, R. Waber, D. Van Tegelen, G. Simons O217 11:42 Development and evaluation of a novel multiplex assay using RenDx® surface enhanced resonance Raman scattering (SERRS) technology to aid in the diagnosis of invasive fungal disease L. White* (Cardiff, United Kingdom), J. Green, M. Perry, G. McNay, R. Stevenson, R. Barnes O218 11:54 Microsatellite-based molecular typing method for Pneumocystis jirovecii M. Gits-Muselli, J. Menotti, N. Guigue, S. Bretagne, A. Alanio* (Paris, Franc) O219 12:06 Characterisation of a PCR/ESI-MS assay for detection and identification of diverse fungi in bronchoalveolar lavage specimens R. Lovari* (Carlsbad, United States), D. Metzgar, D. Toleno, H. Carolan, L. Blyn, S. Peterson, K. Carroll, S. Zhang, F. D'Alessio, R. Rothman Juan P. Horcajada (Spain) 11:30 – 12:30 HALL I Overview & Programme 11:30 A new diagnostic assay for the detection of SY292 12:00 Con SYMPOSIUM: Mycobacteria in cutaneous infections ESGMYC Chairs: Dick van Soolingen (The Netherlands) Miguel Viveiros (Portugal) ePosters O216 Helen Giamarellou (Greece) SY293 11:30 Buruli ulcer due to M. ulcerans Francoise Portaels (Belgium) SY294 12:00 Leprosy: the old and new leprosy bacilli Stewart T. Cole (Switzerland) Posters Chairs: Giuliana Lo Cascio (Italy) Emmanuel Roilides (Greece) SY291 11:30 Pro arranged with the ESCMID Study Group for Mycobacterial Infections (ESGMYC) 11:30 – 12:30 HALL J SYMPOSIUM: HIV and hepatitis C co-infection: double trouble? Chairs: Linos Vandekerckhove (Belgium) Massimo Puoti (Italy) SY295 11:30 HIV-HCV co-infection: wait or treat? Chairs, Speakers & Authors ORAL SESSION: Advances in molecular mycology: notes from the bench Exhibition HALL F Jürgen Rockstroh (Germany) SY296 12:00 Interferon-free treatment for chronic hepatitis C – how and when? Jean-Michel Pawlotsky (France) 24th ECCMID / Barcelona Final Programme 69 General Information 11:30 – 12:30 Scientific Programme Tuesday, 13 May 2014 13:30 – 15:30 HALL A SYMPOSIUM: Controlling transmission of multidrug-resistant pathogens in the intensive care unit Chairs: Francesco Menichetti (Italy) Jose Antonio Martinez Martinez (Spain) SY297 13:30 Decolonisation options for MRSA, VRE, ESBL and CPE: efficacy and safety Christian Brun-Buisson (France) SY299 14:30 MDRO screening and targeted decolonisation strategy Marc J.M. Bonten (The Netherlands) SY300 15:00 Universal decolonisation strategy HALL B EVASG Chairs: Pier Luigi Lopalco (Sweden) Mark Muscat (Denmark) SY301 13:30 Measles and rubella eradication Mark Muscat (Denmark) SY302 14:00 Vaccine pipeline in China: current achievements and bright future James Wai-Kuo Shih (China) SY303 14:30 Reducing the burden of pneumococcal disease with pneumococcal conjugate vaccines Ron Dagan (Israel) SY304 15:00 Use of conjugate vaccines for prevention of meningococcal disease Susanna Esposito (Italy) arranged with the ESCMID Vaccine Study Group (EVASG) Final Programme SY305 13:30 Etiology and consequences of surgical site Andreas F. Widmer (Switzerland) SY307 14:30 Surgical antimicrobial prophylaxis in solid organ transplantation (SOT): which antibiotic for which microorganism? Nicola Petrosillo (Italy) surgery with foreign body implantation? Alex Soriano (Spain) SYMPOSIUM: Hot topics in vaccine-preventable diseases 24th ECCMID / Barcelona Chairs: Joseph S. Solomkin (United States) Matthew Dryden (United Kingdom) SY308 15:00 Is it necessary to modify the prophylaxis in Susan S. Huang (United States) 70 SYMPOSIUM: Antimicrobial prophylaxis of surgical site infections: time to review? SY306 14:00 When do you need to administer the prophylaxis? epidemiological and clinical determinants Stephan J. Harbarth (Switzerland) HALL C infections Werner Zimmerli (Switzerland) SY298 14:00 Effectiveness of MDRO decolonisation: 13:30 – 15:30 13:30 – 15:30 Scientific Programme Tuesday, 13 May 2014 O227 Nile virus strains in northern Italy L. Barzon* (Padua, Italy), M. Pacenti, E. Franchin, E. Lavezzo, L. Squarzon, G. Masi, S. Pagni, M. Cattai, R. Cusinato, G. Palù ORAL SESSION: Emerging infectious diseases Chairs: Albert D.M.E. Osterhaus (The Netherlands) Eskild Petersen (Denmark) O228 13:30 Long-term epidemiological pattern and disease consumption. The last two decades: a systematic review M. Bellou* (Patras, Greece), A. Birmpa, P. Kokkinos, A. Vantarakis burden of dengue in Venezuela L. Echezuria, M. Fernandez, J. Torres* (Caracas, Venezuela), A. Rizquez, P. Romero O223 O224 14:06 Acceptance of vaccinations in pandemic outbreaks: a discrete choice experiment in The Netherlands D. Determann* (Rotterdam, The Netherlands), I.J. Korfage, M.S. Lambooij, M.C.J. Bliemer, J.H. Richardus, E.W. Steyerberg, E.W. De Bekker-Grob O225 mikurensis in Ixodes ricinus and natural vertebrate hosts in southern Sweden M. Andersson* (Lund, Sweden), K. Scherman, L. Råberg O230 13:30 – 15:30 Chairs: Yehuda Carmeli (Israel) José Garnacho-Montero (Spain) SY309 13:30 Empirical therapy for MDR and XDR Gram-negatives Mical Paul (Israel) SY310 14:30 West Nile virus excreted in urine during acute infection is infectious M. Pacenti, R. Cusinato, E. Franchin, L. Squarzon, G. Marcati, M. Cattai, G. Palù, L. Barzon* (Padua, Italy) 14:00 Definitive therapy for ESBL-producers: life beyond carbapenems? Jesús Rodríguez-Baño (Spain) SY311 O226 HALL E SYMPOSIUM: Case-based decisions in the era of XDR Gram-negatives: towards individualised therapy? 14:18 Outbreak of phlebovirus infection in Lombardia, a northen Italy region in summer 2013 E. Percivalle, A. Sarasini, G. Campanini, B. Mariani, A. Pan, F. Moschiano, E. Marchioni, M. Gramegna, M. Fabbi, F. Baldanti* (Pavia, Italy) 15:18 Accuracy of clinical diagnosis of dengue fever in southern Sri Lanka, 2012- 2013 C.K. Bodinayake* (Galle, Sri Lanka), L.G. Tillekeratne, A. Nagahawatte, W. Kodikara Arachchi, V. Devasiri, D. Vidanagama, T. Ostbye, D.J. Gubler, C.W. Woods, M.E. Reller 13:54 Significant changes in the epidemiology of bloodstream infections (BSI): results of a prospective, longitudinal, region-wide survey conducted between 2007 and 2013 C. Danet, H. Gbaguidi-Haore, S. Borges Dos Santos, N. Girard, R. Quentin, N. Van der Mee-Marquet* (Tours, France), BSI Study Group 15:06 The tick-borne pathogen Candidatus Neoehrlichia 14:30 Definitive therapy for carbapenemase-producing Enterobacteriaceae: MIC matters? Mario Tumbarello (Italy) SY312 15:00 XDR-Pseudomonas aeruginosa and Acinetobacter Gokhan Metan (Turkey) 24th ECCMID / Barcelona Final Programme Overview & Programme genomic clades and epigenetic barriers restricting widespread recombination and horizontal gene transfer T. Nandi* (Singapore, Singapore), M.T.G. Holden, J.A. Boddey, I. Beacham, S.L. Chen, R. Titball, J. Parkhill, P. Tan O229 ePosters 13:42 Burkholderia pseudomallei sequencing identifies Posters O222 14:54 Viral outbreaks linked to fresh produce 71 Chairs, Speakers & Authors O221 14:42 Multiple introductions and local evolution of West Exhibition HALL D General Information 13:30 – 15:30 Scientific Programme Tuesday, 13 May 2014 13:30 – 15:42 HALL F O235 invasive aspergillosis C. Garcia Vidal* (Barcelona, Spain), M. Peghin, C. Cervera, C. Gudiol, I. Ruiz-Camps, A. Moreno, C. Royo-Cebrecos, J. Ayats, J. Carratalà ORAL SESSION: Clinical mycology update 2014 Chairs: Andreas H. Groll (Germany) Susan J. Howard (United Kingdom) O236 O230a 13:30 A phase 3 randomised, double-blind trial evaluating isavuconazole vs. voriconazole for the primary treatment of invasive fungal disease caused by Aspergillus spp. or other filamentous fungi (secure) J. Maertens* (Leuven, Belgium), T. Patterson, G. Rahav, D. Kontoyiannis, K. Marr, R. Maher, M. Lee, B. Zeiher, A. Ullmann O231 O232 O233 14:06 Decreased invasive fungal disease but no impact on overall survival by posaconazole compared to fluconazole prophylaxis; a retrospective cohort study in AML and MDS patients T. Dahlén* (Stockholm, Sweden), K. Cederlund, M. Kalin, A. Nordlander, M. Björkholm, P. Ljungman, O. Blennow O234 14:18 Accuracy of bis(methylthio)gliotoxin in diagnosis of invasive pulmonary aspergillosis: a comparative study with galactomannan M. Vidal García* (Zaragoza, Spain), M.P. Domingo, P. Soria, C. Lapresta, P. Delgado, M.J. Revillo, J. Pardo, E.M. Gálvez, A. Rezusta 72 O237 24th ECCMID / Barcelona Final Programme 14:54 The strategies for treating persistent candidaemia: do echinocandins do better? K.Y. Lin* (Taipei City, Taiwan), P.Y. Chen, H.Y. Sun, C.C. Lai, Y.C. Chuang, W.H. Sheng, Y.C. Chen, S.C. Chang O238 15:06 Antifungal stewardship at a London teaching hospital achieves sustained cost reduction over 3 years without compromising microbiological and clinical outcomes L. Whitney* (London, United Kingdom), H. Al-Ghusein, M. Koh, M. Klammer, T. Bicanic 13:54 Impact of early antifungal treatment on invasive- candidiasis-free survival in ICU patients ventilated for more than 4 days. A pseudorandomised trial based on marginal structural models S. Bailly, R. Hamidfar-Roy, M. Garrouste-Orgeas, M. Darmon, M. Cornet, S. Ruckly, S. Chemam, C. Adrie, M. Rabilloud, J.F. Timsit* (Grenoble, France) 14:42 Multi-country estimate of different manifestations of aspergillosis in adult cystic fibrosis patients J. Armstead* (Cheshire, United Kingdom), D.W. Denning 13:42 Worrisome trends in incidence and mortality of candidaemia in intensive care units (Paris area, 2002-2010) O. Lortholary* (Paris, France), C. Renaudat, K. Sitbon, L. Denoeud-Ndam, M. Wolff, A. Fontanet, S. Bretagne, F. Dromer, F.M.S.G. French Mycoses Study Group 14:30 Current causes of death for patients with O239 15:18 Reversed halo sign; the clinical meanings and the formation processes during neutropenia, a cohort study K. Kyo* (Hiroshima, Japan), K. Toishigawa, T. Ochi, T. Okatani, R. Imanaka, M. Itagaki, Y. Katayama, K. Iwato, H. Asaoku, T. Kyo O240 15:30 IL17A and IL22 in patients with candidaemia, Candida-colonised ICU patients and healthy controls R. Krause* (Graz, Austria), I. Zollner-Schwetz, T. Valentin, R. Raggam, B. Rinner, F. Quehenberger, M. Hönigl Scientific Programme Tuesday, 13 May 2014 O248 antimicrobial therapy outcomes in acute care – a prospective cross-sectional study E. Charani* (London, United Kingdom), M. Gharbi, G. Frost, A.H. Holmes ORAL SESSION: New old antibiotics: safety and efficacy Chairs: Roger L. Nation (Australia) Benito Almirante (Spain) O249 O241 13:30 Colistin-associated nephrotoxicity in critically ill patients and simulated colistimethate sodium and colistin levels T.P. Gauthier* (Fort Lauderdale, United States), W.R. Wolowich, E. Cano, J. Altamirano, P. Laowansiri, A. Reddy, J. Wasko, E. Lantz, L. Smith, L. Abbo O242 13:42 Risk factors for acute kidney injury in patients treated with polymyxin B according to RIFLE and AKIN scores: a prospective cohort study M.H. Rigatto* (Porto Alegre, Brazil), L.C. Antochevis, L.W.L. Costa, D.R. Falci, T. Freitas, N.T. Lopes, F.R. Vieira, A.P. Zavascki O243 14:54 Adult weight and its impact on infection and 15:06 Is the efficacy of ertapenem reduced in the presence of severe hypoalbuminaemia? L. Farbman* (Tel Aviv, Israel), O. Zusman, Z. Tredler, V. Daitch, A. Lador, L. Leibovici, M. Paul O250 15:18 Outcome of patients with bacteraemia due to Enterobacteriaceae treated with fluoroquinolones accruing to MIC (REIPI bacteraemia-MIC study) E. Torres* (Seville, Spain), C. Peñas, M. Delgado-Valverde, A.M. Planes, C. Peña Miralles, N. Borrell, J. Corzo Delgado, A. Valiente Mendez, A. Pascual, J. Rodriguez-Baño Overview & Programme HALL G 13:54 The potential role of phosphomycin in combating O244 ePosters ESBL-producing organisms causing urinary tract infections in district general hospital in the UK A. Ghazy* (Southall Middlessex, United Kingdom), S.A. Aali, P. Khanna, K. Cheema, W. Lynn 14:06 Colistin-associated nephrotoxicity: the impact of definition J.M. Pogue* (Detroit, United States), D. Marchaim, K. Hayakawa, H. Pulluru, K.S. Kaye 14:18 Safety of daptomycin at different doses: results Posters O245 O246 Chairs, Speakers & Authors from EU-CORE(SM) and from post-marketing surveillance K. Malizos* (Basel, Switzerland), R. Utili, P. Gargalianos-Kakolyris, G. Dalekos, R.A. Seaton, P. Dohmen, S. Titaevski, K. Bouylout, A. Trylesinski 14:30 Fluoroquinolones and the risk of severe arrythmia – a nationwide cohort study M. Inghammar* (Lund, Sweden), B. Pasternak, H. Swanström, A. Hviid, M. Melby 14:42 Fluoroquinolones and QT prolongation in the Exhibition O247 clinical setting: study of their impact in the heavily predisposed hospitalised population M. Zorzou* (Chios, Greece), A. Kosti, M. Stoupaki, A. Kallergi, S. Skoulikidi, E. Papadopoulou, A. Pitsikouli, M. Psallas, P. Pramangioulis, G. Dounias 24th ECCMID / Barcelona Final Programme 73 General Information 13:30 – 15:30 Scientific Programme Tuesday, 13 May 2014 13:30 – 15:30 HALL H O258 A. Dinh* (Paris, France), I. Ghout, D. Mulleman, B. Marchou, B. Issartel, V. Zeller, N. Belmatoug, M. Dupon, L. Bernard ORAL SESSION: Improving treatment of severe infections Chairs: Jose Miguel Cisneros Herreros (Spain) M. Adriana Cataldo (Italy) O251 O259 13:42 Antistaphylococcal beta-lactams vs vancomycin O260 in the treatment of infective endocarditis due to methicillin-susceptible coagulase-negative staphylococci – a prospective cohort study from the international collaboration on endocarditis M. Carugati* (Milan, Italy), C. Arnold, J. Miro', Z. Kanafani, A. Bayer, V. Chu O253 13:54 Effect of days of therapy on detection of pathogens from sterile clinical specimens submitted for culture following initiation of antibiotic treatment J.J. Farrell* (Peoria, United States), H. Wang, R. Sampath, R.A. Bonomo 13:30 – 15:30 ESGAI, Society for Anaerobic Microbiology Chairs: Dorothea Orth (Austria) Elisabeth Nagy (Hungary) SY314 O256 14:30 Cost-effectiveness of fidaxomicin as first-line treatment for Clostridium difficile infection J. Nesnas, L. Whitney, A. Ahmad, T. Planche* (London, United Kingdom) O257 14:42 Appropriate empiric antibiotic treatment does not reduce 30-day mortality among inpatients with catheter-associated urosepsis: observational cohort study T. Babich* (Petah Tikva, Israel), T. Avni, M. Paul, L. Leibovici 74 24th ECCMID / Barcelona Final Programme 14:00 Escape from the biofilm – disseminated oral anaerobic infections Riina Richardson (United Kingdom) 14:18 Tailoring the empirical antimicrobial therapy in VAP patients by means of an E-test based direct testing F. M'Zali* (Bordeaux, France), J. Goret, E. Chalus, D. Anquetil, C. Bouchiat, B. Clouzeau, H.N. Bui, M. Kann, D. Gruson, A. Boyer 13:30 More than a nasty smell – burden of emerging anaerobes in the era of molecular detection Bernard La Scola (France) SY315 O255 HALL I SYMPOSIUM: Two-faced companions: highlights in the world of anaerobes 14:06 In vivo development of fluoroquinolone and macrolide resistance in Streptococcus pneumoniae M. Alonso, J.M. Marimon Ortiz de Zarate* (San Sebastian, Spain), I. De la Caba, M. Ercibengoa, E. Pérez-Trallero 15:18 Colistin and tobramycin resistance during long-term use of selective decontamination strategies in Dutch ICUs B.H.J. Wittekamp* (Utrecht, The Netherlands), E.A.N. Oostdijk, M.J.M. Bonten SY313 O254 15:06 Long-term benefit from clarithromycin treatment in patients with sepsis and ventilator-associated pneumonia (VAP): impact on the hospitalisation cost T. Tsaganos* (Haidari, Greece), M. Raftogiannis, M. Pratikaki, S. Christodoulou, A. Kotanidou, E. Papadomichelakis, C. Routsi, E.J. Giamarellos-Bourboulis 13:30 Cross-sectional study: an international survey on controversial antibiotic options in infective endocarditis G. Béraud* (Poitiers, France), C. Pulcini, J.R. Paño-Pardo, B. Hoen, B. Beovic, D. Nathwani O252 14:54 Antibiotic treatment of vertebral osteomyelitis 14:30 Anaerobes in medical device infections – a failed diagnosis? Sheila Patrick (United Kingdom) SY316 15:00 Anaerobes in sinusitis and chronic respiratory tract infections Kenneth Bruce (United Kingdom) arranged with the ESCMID Study Group for Anaerobic Infections (ESGAI) and with the Society for Anaerobic Microbiology (SAM) Scientific Programme Tuesday, 13 May 2014 HALL J O268 detection of pathogens in patients with suspected sepsis A. Onnberg* (Örebro, Sweden), I. Ziegler, B. Törös, K. Strålin, P. Mölling ORAL SESSION: PCR and other molecular tests directly on blood: what is new? Chairs: Jean-Luc Mainardi (France) Paul Savelkoul (The Netherlands) O269 O261 13:30 Bench to bedside: rapid identification and 13:42 Development and initial characterisation of a PCR/ESI-MS assay capable of detecting and identifying diverse bacteria and Candida in normally sterile body fluids and tissues M. Frinder, D. Metzgar* (Carlsbad, United States), M. Rounds, H. Carolan, D. Toleno, R. Sampath, L. Blyn O263 15:06 Matrix-assisted laser desorption/ionization-time of flight mass-spectrometry (MALDI-TOF MS) directly from positive blood culture flasks allows rapid detection and identification of bloodstream infection (BSI) A. Egli* (Basel, Switzerland), M. Osthoff, D. Goldenberger, M. Weisser, R. Frei susceptibility testing of Staphylococcus aureus from blood culture isolates M. Menon* (Newcastle, Australia), C. Pedersen, A. Foster, P. Kalukottege, J. Davis, S. Graves O262 14:54 Magicplex™ sepsis real-time PCR for rapid O270 15:18 Molecular epidemiology and characterisation of S. aureus bacteraemic isolates during four decades in Sweden G. Rasmussen* (Örebro, Sweden), S. Monecke, R. Ehricht, B. Söderquist Overview & Programme 13:30 – 15:30 13:54 Evaluation of the FilmArray® blood culture O264 ePosters identification panel in identification of polymicrobial blood culture bottles A. Giaquinto, F. Arena, T. D'Inzeo, B. Fiori, G. De Angelis* (Rome, Italy), G. Menchinelli, L. Piccioni, M. Sanguinetti, G.M. Rossolini, T. Spanu 14:06 Accuracy and potential clinical utility of two 14:18 Rapid detection of Gram-negative bacteria and O266 Chairs, Speakers & Authors resistance determinants directly from positive blood cultures using the microarray-based sample-to-result Verigene® BC-GN assay N.A. Ledeboer* (Milwaukee, United States), T.A. Mackey, B.W. Buchan 14:30 Impact of the Verigene® Gram-positive blood O267 Exhibition culture assay in a tertiary care paediatric hospital S. Felsenstein* (Los Angeles, CA, United States), C. Taketomo, P. Sandha, J. Dien Bard 14:42 Field evaluation of the new QuickFISH™ assays for the rapid diagnosis of sepsis A. Calderaro* (Parma, Italy), M. Martinelli, F. Motta, S. Montecchini, C. Gorrini, M.C. Arcangeletti, F. De Conto, C. Chezzi, M.C. Medici 24th ECCMID / Barcelona Final Programme 75 General Information O265 Posters rapid molecular panels for detection of bloodstream infection C. Ward* (London, United Kingdom), K. Stocker, J. Begum, P. Wade, U. Ebrahimsa, S. Goldenberg 3rd ESCMID Conference on Vaccines Vaccines for Mutual Protection Lisbon, Portugal 6 – 8 March 2015 Organising Committee Ron Dagan, Beer Sheva, IL Susanna Esposito, Milan, IT Mario Poljak, Ljubljana, SI Contact: [email protected] Find more information and registration information on our website www.escmid.org/lisbon2015 Including: • Mutual protection – the key for disease prevention • Influenza – how best to prevent transmission • Recent threats of poliovirus – did we open the Pandora box? • Safety issues in vaccines – potential risk for mutual protection • Pertussis protection throughout life – how can we achieve this? • New insight into prevention of gastrointestinal infections in all ages • Can we achieve meningococcal control in Europe? • How can we achieve HPV control in Europe? ePoster Sessions Sunday, 11 May 2014 eP042 13:06 Risk factors for surgical site infection after microvascular reconstruction for head and neck cancer J.L. Wagner* (Detroit, United States), R.M. Kenney, T.A. Ghanem, J.A. Vazquez, S.L. Davis eP044 13:12 Sternal plate fixation for chest wall reconstruction post coronary artery bypass surgery appears to increase the risk of surgical site infection M. Charles* (Edmonton, Canada), L. Saxinger, S. Smith eP041 13:18 Infection of spinal cord stimulation devices: remove or retain? G. Béraud* (Poitiers, France), M. Roulaud, O. Monlezun, F. Guetarni, B. Bataille, P. Rigoard eP053 13:24 Impact of multidrug-resistant Gram-negative bacilli on organ/space infections associated to elective colorectal surgery – a prospective analysis in a university hospital in Spain E. Shaw* (Barcelona, Spain), R. Escofet, G. Cuervo, D. Garcia, O. Arch, A. Hornero, T. Vidal, C. Peña, J. Ariza, M. Pujol eP055 13:30 Post-arthroscopic septic arthritis of the knee analysis of the outcome after treatment in a series of cases T. Ascione* (Naples, Italy), G. Balato, P. Pagliano, R. Rotondo, G. De Stefano, M. Conte, M. Mariconda eP056 13:36 Management and clinical outcomes of Staphylococcus aureus prosthetic joint infections: a retrospective review S. Parsaei* (Saint Louis, MO, United States), N. Ganeshraj, A. Gu, P. Bodavula, J. Marschall, D. Warren, M. Lane eP058 13:42 SSI after hip or knee arthroplasty: a French cohort study using hospital discharge database, 2008-2012 L. Grammatico-Guillon* (Tours, France), S. Baron, C. Gaborit, E. Rusch, P. Astagneau eP060 13:54 Standards of infection control to prevent surgical site infections in Switzerland: a cross-sectional survey in 82 hospitals D. Vuichard Gysin* (Basel, Switzerland), N. Troillet, M.C. Eisenring, M. Dangel, G. Zanetti, A.F. Widmer 13:00 – 14:00 HALL F EPOSTER SESSION: PK/PD to improve treatment of critically ill patients eP002 13:00 Impact of beta-lactam pharmacokinetics/ pharmacodynamics on clinical outcome of bloodstream infections in critically ill patients M. Nunez-Nunez* (Seville, Spain), G. Wong, S.C. Wallis, B. McWhinney, J.P.G. Ungerer, J. Mayer, J. Lipman, J.A. Roberts ePosters related to craniotomy in a tertiary care university hospital – a prospective surveillance programme A. Soriano* (Barcelona, Spain), E. Shaw, O. Arch, A. Gabarros, D. Garcia, C. Cabellos, I. Pelegrin, C. Peña, J. Ariza, M. Pujol eP008 13:06 Population pharmacokinetics of ceftazidime and cefepime in septic shock patients during continuous renal replacement therapy M. Carlier* (Ghent, Belgium), F. Taccone, L. Seyler, F. Jacobs, M. Beumier, J.L. Vincent, J. Lipman, J. Roberts Posters eP039 13:00 Risk factors and surgical site infection rates duration of antibiotic prophylaxis for prevention of neurosurgical infections A. Ulu-Kilic* (Kayseri, Turkey), E. Alp Mese, F. Cevahir, H. Demiraslan, B. Tucer, A. Selcuklu, M. Doganay eP004 13:12 Pharmacokinetic/pharmacodynamic evaluation of the efficacy and cost-effectiveness of various carbapenem dosing regimens for the treatment of Gram-negative bacterial bloodstream infections T.P. Lim, Y. Cai, J. Teo, Z.W. Wang, W. Lee, T.Y. Tan, T.T. Tan, L.Y. Hsu, T.H. Koh, A. Kwa* (Singapore, Singapore) eP005 13:18 The effect of extracorporeal membrane oxygenation in critically ill patients on meropenem pharmacokinetics: a matched cohort study J. Roberts* (Brisbane, Australia), K. Shekar, J. Fraser, D. Mullany, S. Wallis, J. Lipman 24th ECCMID / Barcelona Final Programme 77 Chairs, Speakers & Authors EPOSTER SESSION: Post-surgical and implant infections: from head to knee eP040 13:48 Cost-effectiveness analysis of appropriate Exhibition HALL D General Information 13:00 – 14:00 ePoster Sessions Sunday, 11 May 2014 eP006 13:24 Comparative evaluation of the accuracy and precision of pharmacokinetic equations to predict free meropenem concentrations in critically ill patients A. Farkas, G. Wong, G. Daroczi, J. Lipman, J. Roberts* (Queensland, Australia) eP007 13:30 Microdialysis tissue pharmacokinetics and pharmacokinetic-pharmacodynamic modelling of ertapenem after 1g/12h administrations to critically ill patients N. Gregoire* (Poitiers, France), N. Hamitouche, L. Laksiri, T. Loupec, S. Marchand, O. Mimoz, W. Couet eP009 13:36 Explaining variability in gentamicin peak concentrations to optimise gentamicin dosing in critically ill patients R.M. Van Hest* (Amsterdam, The Netherlands), C.S.C. Bouman, C.E. Visser, N.P. Juffermans, C.J. Hodiamont, R.A. Mathot eP010 13:42 Amikacin peak loading in obese patients: application of adjusted body weight formula with modern posologies. Are 30 mg/kg enough? C. Lu, M. Meddour, N. Van Grunderbeeck* (Lens, France), M. Nyunga, M. Boyer-Besseyre, J. Gois, E. Parmentier-Decrucq, J. Mallat, D. Thevenin, N. Lemaire eP001 13:48 Population probability of target attainment of colistin at different levels of renal function against Pseudomonas aeruginosa and Acinetobacter baumannii in Europe A. Farkas, K. Hoffman, C. Levy, J. Roberts* (Queensland, Australia) 13:00 – 14:00 HALL G EPOSTER SESSION: Microbiome and resistance: what are they telling us? eP492 13:00 Gut microbiota continues to evolve during the first five years of life A. Eck* (Amsterdam, The Netherlands), N.B.M.M. Rutten, I. Besseling-van der Vaart, G.T. Rijkers, A.M. De Vlieger, P.H.M. Savelkoul, A.E. Budding 78 24th ECCMID / Barcelona Final Programme eP490 13:06 Profile similarities of gut microbiota in allergic and non-allergic children at 5 and 10 years of age T. Drell* (Tartu, Estonia), A. Larionova, J. Simm, K. Heilman, T. Voor, E. Sepp eP493 13:12 Effects of selective digestive decontamination (SDD) on the gut resistome E. Bülow* (Utrecht, The Netherlands), T. Bello Gonzalez, D. Versluis, L. Ogilvie, M.M. D’Andrea, H. Smidt, B.V. Jones, R.J.L. Willems, M. Bonten, W. Van Schaik eP496 13:18 Use of the mucosal F. prausnitzii/E.coli index as a marker of microbiota improvement in ulcerativecolitis dysbiosis after treatment with mesalazineMMX (Mezavant™) J. Miquel Cusachs* (Girona, Spain), D. Busquets Casals, M. Serra-Pagès, J. Garcia Gil, X. Aldeguer Manté eP502 13:24 Searching for peritonitis-causing agents in the normal microbiota of peritoneal dialysis patients: analysis of possible routes of infection L. Simões Silva* (Porto, Portugal), S. Ferreira, S. Silva, R. Araujo, M.J. Sousa, C. Santos-Araújo, M. Pestana, I. Soares-Silva, B. Sampaio-Maia eP498 13:30 The oral resistome: from metagenomics to antimicrobial resistance of the microbiota in the mouth B.B. Wintermans* (Amsterdam, The Netherlands), C.M.J.E. Vandenbroucke-Grauls, A.E. Budding eP500 13:36 Molecular identification of bacterial communities associated with caries by denaturing gradient gel electrophoresis fingerprinting approach E. Alia, B. Romero-Hernández* (Madrid, Spain), A.M. Sánchez-Díaz, J.D. Caballero, M. Hernández-García, G. Chinchón, D. Parra-Pecharomán, J. López-Palafox, L. Gil, R. Del Campo eP488 13:42 The vaginal microbiome as a predictor for acquiring Chlamydia trachomatis, a case control study R. Van Houdt* (Amsterdam, The Netherlands), B. Ma, J. Van der Helm, S. Bruisten, H. De vries, J. Ravel ePoster Sessions Sunday, 11 May 2014 eP572 13:36 High rates of sexually transmitted infections in eP555 13:00 Optimisation of the diagnostic strategy for detecting C. trachomatis as a cause of female infectious infertility K. Gillmann, M.K. Bohlmann, R. Speer, H. Mark, S. Graspeuntner, A. Schultze- Mosgau, R. Lettau, G. Griesinger, I. König, J. Rupp* (Lübeck, Germany) eP561 13:06 Genital Chlamydia trachomatis testing and care in general practice in UK, France, Sweden and Estonia A. Uusküla, E. Ricketts, R. Kalda, A. Tisler-Sala* (Tartu, Estonia), H. Fredlund, J. Hedlund, B. Dunais, B. Touboul, C. McNulty eP564 13:12 Prevalence and predictors of lymphogranuloma venereum in a high-risk population in Italy A. Marangoni* (Bologna, Italy), C. Foschi, A. D’Antuono, M. Compri, P. Nardini, S. Bellavista, N. Banzola, A. Filippini, R. Cevenini eP578 13:18 Infection with Chlamydia trachomatis in infertile women in Poland I. Chudzicka-Strugala* (Poznan, Poland), T.M. Karpinski, A. Zeidler, B. Banaszewska, L. Pawelczyk, A. Szkaradkiewicz eP566 13:24 Prevalence and risk factors associated with Mycoplasma genitalium infection in a South African women cohort J.-H. Dubbink, B. Hay, S. Ouburg, C. Le Roy, S. Pereyre, S.A. Morré, C. Bebear* (Bordeaux, France), R.H. Peters eP570 13:30 High prevalence of HIV infection in homo/bisexual men with other sexually transmitted diseases R. Del Romero* (Madrid, Spain), B. Menéndez, T. Puerta, J. Balllesteros, P. Clavo, M. Vera, M. Raposo, V. Paredes, C. Rodríguez, I. Río age groups of symptomatic patients S. Baka, I. Tsirmpa* (Athens, Greece), E. Saltaoura, A. Chasiakou, S. Hassiakou, V. Gennimata, E. Kouskouni eP576 13:48 Global prevalence of recurrent vulvovaginal candidiasis D.W. Denning, M. Kneale, R. Rautemaa-Richardson* (Manchester, United Kingdom), J.D. Sobel 13:00 – 14:00 HALL I EPOSTER SESSION: Antifungal drug susceptibility and resistance eP232 13:00 Echinocandin MICs against Candida species at hospitals that routinely perform susceptibility testing of bloodstream isolates G. Eschenauer, M.H. Nguyen, S. Shoham, J. Vazquez, A. Morris, C. Kubin, P. Carver, K. Hanson, S. Chen, C.J. Clancy* (Pittsburgh, United States) ePosters EPOSTER SESSION: STD and other genital infections 13:42 Prevalence of aerobic vaginitis among different eP235 13:06 Species distribution and antifungal susceptibilities of bloodstream Candida sp. from the Asia-Pacific region T.Y. Tan* (Singapore, Singapore), L.Y. Hsu, M.M. Alejandria, T. Chinniah, P. Kiratisin, J.H. Shin, T.T.N. Tran, A.L. Tan, L.S.Y. Ng Posters HALL H eP575 eP242 13:12 Echinocandin failure case due to a yet unreported FKS mutation in Candida krusei R. Jensen* (Copenhagen, Denmark), U. Justesen, A. Rewes, D. Perlin, M. Arendrup eP243 13:18 Twofold point mutations in Candida albicans FKS1 gene leading to echinocandin resistance after long-term treatment K. Heidrich, R. Krause* (Graz, Austria), M. Hoenigl, C. Lass-Floerl, W. Buzina Chairs, Speakers & Authors 13:00 – 14:00 HIV-infected individuals attending an STD clinic in the US J. Castro* (Miami, United States), M. Alcaide Exhibition of healthy pregnant women of four ethnic backgrounds, and of Caucasian pregnant women in health and disease G.L. Mendz* (Darlinghurst, NSW, Australia), S.J. Lord, N.O. Kaakoush, J.A. Quinlivan eP238 13:24 Is micafungin uniformly active against Candida albicans biofilms showing different degrees of metabolic activity? L.J. Marcos-Zambrano, P. Escribano, E. Bouza, J. Guinea Ortega* (Madrid, Spain) 24th ECCMID / Barcelona Final Programme 79 General Information eP489 13:48 Comparisons of the vaginal microbiomes ePoster Sessions Sunday, 11 May 2014 eP246 13:30 Aspergillus fumigatus with prior azole exposure decreases amphotericin B sensitivity in vitro R. Rajendran* (Glasgow, United Kingdom), C. Williams, B. Jones, G. Ramage eP247 13:36 Investigation of primary clinical samples and azole-resistant isolates of immunocompromised patients for cyp51A mutations in Aspergillus fumigatus using established and a novel TR46 PCR assays B. Spiess* (Mannheim, Germany), P. Postina, A. Hamprecht, J. Vehreschild, C. Lass-Flörl, M. Hönigl, P.-M. Rath, T. Miethke, W.-K. Hofmann, D. Buchheidt eP252 13:42 First Danish report of TR34/L98H A. fumigatus in three non-cystic fibrosis patients despite apparent lack of resistant isolates in recent soil samples K.M.T. Astvad* (Valby, Denmark), R.H. Jensen, T.M. Hassan, E.G. Mathiasen, G.M. Thomsen, U.G. Pedersen, M. Christensen, M.C. Arendrup eP249 13:48 Simple, low-cost molecular detection of TR34/ L98H mutations in cyp51A gene for rapid detection of triazole-resistant Aspergillus fumigatus isolates S. Ahmad* (Safat, Kuwait), Z. Khan, L. Joseph, F. Hagen, J. Meis, J. Meis eP259 13:54 Optimising antifungal combination therapy of voriconazole+amphotericin B against Aspergillus fumigatus using a pharmacokineticpharmacodynamic (PK-PD) model M. Siopi* (Athens, Greece), N. Siafakas, L. Zerva, J. Meletiadis 80 24th ECCMID / Barcelona Final Programme ePoster Sessions Monday, 12 May 2014 HALL D eP171 tested against vancomycin-resistant/susceptible enterococcal clinical isolates recovered from European medical centres (2009-2013) R.E. Mendes* (North Liberty, United States), D.J. Farrell, J.M. Streit, R.N. Jones EPOSTER SESSION: Antibacterial drug activity and interactions in Gram-positive organisms eP193 13:00 Activity of ceftaroline against clinically relevant strains of penicillin non-susceptible S. pneumoniae I. Burckhardt* (Heidelberg, Germany), J. Panitz, P. Jaehn, S. Zimmermann eP189 13:42 In vitro and in vivo susceptibility of Streptococcus pyogenes to trimethoprim-sulphamethoxazole in northern Australia A.C. Bowen* (Casuarina, Australia), S.Y.C. Tong, M.I. McDonald, J.R. Carapetis eP180 13:06 Allosteric site missense mutations in PBP2a affecting ceftaroline susceptibility detected in epidemic HA-MRSA clonotypes ST228 (south German) and ST247 (Iberian) in western Switzerland W.L. Kelley, A. Jousselin, C. Barras, E. Lelong, A. Renzoni* (Geneva, Switzerland) eP183 13:12 In vitro activity of ceftaroline against EP15T mecC-positive methicillin-resistant Staphylococcus aureus from humans and livestock E. Cercenado* (Madrid, Spain), F. García-Garrote, M. Marín, A. Vindel, A. Méndez, E. Bouza 13:36 Current analysis of oritavancin potency when eP191 13:48 Antimicrobial activity of solithromycin tested against serotyped macrolide-resistant Streptococcus pneumoniae collected from medical centres across the USA (2012) D.J. Farrell* (North Liberty, IA, United States), R.E. Mendes, R.N. Jones eP192 13:54 Comparison of commercial methods with broth microdilution for determining beta-lactam susceptibilities of Streptococcus pneumoniae isolates M. Charles* (Edmonton, Canada), B. Berenger, L. Turnbull, R. Rennie, J. Fuller ePosters eP176 13:18 Mutant prevention concentration (MPC) values Posters of tedizolid (TDZ) against clinical strains of methicillin-resistant Staphylococcus aureus (MRSA) shows a low propensity for resistance selection A. Alsaeed, S. Shebelski, J. Blondeau* (Saskatoon, SK, Canada) eP185 13:24 Activity of the peptide deformylase inhibitor Chairs, Speakers & Authors GSK1322322 against intracellular forms of susceptible and resistant S. aureus: comparison with azithromycin, clindamycin, linezolid, vancomycin, daptomycin, and moxifloxacin F. Peyrusson, P.M. Tulkens* (Brussels, Belgium), F. Van Bambeke eP184 13:30 The use of natural alkaloids and flavonoids in Exhibition combination with antibiotics to prevent and control Staphylococcus aureus biofilms A.C. Abreu* (Porto, Portugal), I. Gomes, J. Malheiro, M. Simões 24th ECCMID / Barcelona Final Programme 81 General Information 13:00 – 14:00 ePoster Sessions Monday, 12 May 2014 13:00 – 14:00 HALL F EPOSTER SESSION: Assessing and decreasing environmental contamination eP270 13:00 Effects of a syphon disinfection device on colonisation with multiresistant Pseudomonas aeruginosa in sinks on a tertiary care centre ICU E.H.R. Van Essen* (Leiden, The Netherlands), M.G.J. De Boer, R.B.P. De Wilde, H.C.M. DogteromBallering, K.E. Veldkamp, E. De Jonge eP271 13:06 Bath basins in healthcare settings from Europe and North America as common reservoirs for multi-drug resistant organisms B. Ackerman, K.S. Kaye, D. Marchaim* (Zerifin, Israel) eP263 13:12 Antimicrobial resistant Gram-negative bacilli in the ICU: examining the interplay between patient colonisation and environmental contamination H. McDermott* (Dublin, Ireland), M. Scally, H. Humphreys, D. Fitzgerald-Hughes eP280 13:18 Can toy wash and disinfection reduce bacteria load and sickness in day care centres? T. Ibfelt* (Copenhagen, Denmark), L. Andersen eP281 13:24 Pneumatic transport systems (PTS) are prone to contamination with multiresistant organisms – lessons learned from an Acinetobacter spp. (GIM1) pseudooutbreak at a large university hospital M. Herrmann* (Homburg/Saar, Germany), S. Jungmann, A. Dawson, A. Halfmann, M. Kaase, S. Gatermann, L. Von Müller, B. Gärtner eP275 13:30 A novel approach for in vitro evaluation of the potential risk of patient contamination during endovaginal ultrasound examinations F. MZali* (Bordeaux, France), S. Leroy, M. Kann, C. Quentin-Noury 82 24th ECCMID / Barcelona Final Programme eP276 13:36 Risk of HIV and hepatitis C infection related to endocavitary ultrasound probe exposure T. Bénet* (Lyon, France), J. Ritter, P. Vanhems eP267 13:42 Assessing the efficacy of two commonly used disinfecting agents in hospital isolation rooms M. Smith* (Kilmarnock, United Kingdom), W.G. Mackay, K. Smith, C. Woodall, C.L. Williams, R.G. Masterton eP264 13:48 Decontamination of hospital surfaces using an air plasma multi-jet T. Claro* (Dublin, Ireland), O. Cahill, N. O’Connor, S. Daniels, H. Humphreys eP269 13:54 Using electrolysed water to clean near-patient sites: is disinfectant better than detergent? M. Stewart* (Glasgow, United Kingdom), S.J. Dancer, A. Bogusz, J. Hunter, I. Devanny, B. Yip, D. Reid, C. Robertson ePoster Sessions Monday, 12 May 2014 eP072 13:00 Qualitative and quantitative analysis of the microbiota in lower respiratory tract infections reveals a high proportion of polymicrobial infections G. Platt* (London, United Kingdom), S. Schwenk, Y. Personne, K. Thomas, V. Gant, V.I. Enne, A.I. Zumla eP061 13:06 Microbiological investigation of patients with community-acquired pneumonia using quantitative multiplex real-time bacterial PCR C.D. Russell* (Edinburgh, United Kingdom), N.J. Gadsby, H. Mark, D. Guerendiain, A. Conway Morris, I.F. Laurenson, A.T. Hill, K.E. Templeton eP071 13:12 The value of procalcitonin to determine the need for hospital admission in adults with communityacquired pneumonia A.F. Simonetti* (Barcelona, Spain), D. Viasus, C. Garcia-Vidal, J. Dorca, F. Morandeira-Rego, J. Carratala eP062 13:18 Predictors of bacteraemia in patients hospitalised with suspected community-acquired pneumonia: a cohort study C.H. Van Werkhoven* (Utrecht, The Netherlands), S.M. Huijts, D.F. Postma, J.J. Oosterheert, M.J.M. Bonten among patients with community-acquired pneumonia (CAP): a propensity score-matched analysis of ceftaroline fosamil (CPT-F)-treated vs ceftriaxone-treated patients Y. Golan* (Boston, MA, United States), R. Ruthazer, M. Ding, Q. Zhao, X. Huang eP064 13:42 Beta-lactam monotherapy versus beta-lactam- macrolide combination treatment in moderately severe community-acquired pneumonia: a randomised non-inferiority trial N. Garin* (Geneva, Switzerland), D. Genné, S. Carballo, C. Chuard, G. Eich, O. Hugli, P. Petignat, O. Rutschmann, S. Harbarth, A. Perrier eP065 13:48 In-hospital modifications of antibacterial therapy initiated in the emergency department for community-acquired pneumonia N. Goffinet, M. Cousin, E. Montassier, C. Peron, N. Lecadet, G. Potel, E. Batard* (Nantes, France) eP066 13:54 Antibiotic treatment patterns and outcomes among patients hospitalised in ICU with community-acquired bacterial pneumonia: a US cohort study S. Eapen* (Boston, United States), E. Tuttle, C. Llop, M. Barrett ePosters EPOSTER SESSION: Community-acquired pneumonia eP068 13:36 Mortality and hospital length of stay (HLOS) Posters HALL G eP063 13:24 Factors associated with prolonged time to clinical Chairs, Speakers & Authors stability in hospitalised adults with communityacquired pneumonia A.F. Simonetti, D. Viasus* (Barranquilla, Colombia), C. Garcia-Vidal, J. Carratala eP067 13:30 Impact of initial antibiotic failure on duration of Exhibition hospitalisation (DOH) for community-acquired pneumonia (CAP): results of a randomised clinical trial of ceftaroline fosamil versus ceftriaxone N. Zhong, T. Sun, G. D’Souza, S.H. Lee, H.L. Nguyen, C.-H. Chiang, D. Wilson, F. Sun, D. Melnick* (Wilmington, United States) 24th ECCMID / Barcelona Final Programme 83 General Information 13:00 – 14:00 ePoster Sessions Monday, 12 May 2014 13:00 – 14:00 HALL H eP140 13:30 Development of a novel six-valent recombinant protein vaccine against toxoplasmosis using antigens discovered by high-throughput protein microarray analysis of patient and infected murine model sera M. Doskaya* (Izmir, Turkey), E. Atalay, L. Liang, A. Caner, H. Can, S. Gulce Iz, D.H. Davies, A. Degirmenci Doskaya, P.L. Felgner, Y. Guruz EPOSTER SESSION: Vaccine development eP134 13:00 Safety, tolerability, and immunogenicity of a novel 4-antigen Staphylococcus aureus vaccine (SA4Ag) in healthy adults: results of a randomised, placebo-controlled first-in-human phase 1/2 study R. Frenck* (Cincinnati, United States), C. Buddy Creech, E. Sheldon, D.J. Seiden, M. Kankam, J. Baber, E. Zito, R. Hubler, J. Eiden, J.M. Severs, S. Sebastian, J. Nanra, K.U. Jansen, A.S. Anderson, D. Girgenti eP144 13:36 Knowledge and risk perception of measles and factors associated with vaccination decisions in subjects consulting university affiliated public hospitals after measles infection: a retrospective epidemiological study M. Saadatian-Elahi* (Lyon, France), A. Toure, D. Floret, B. Lina, J.S. Casalegno, P. Vanhems eP146 13:06 Advancing the development of an effective Staphylococcus aureus vaccine by targeting multiple bacterial virulence factors A.S. Anderson, I.L. Scully, P.A. Liberator, D. Cooper* (Pearl River, United States), J. Baber, D.Q. Girgenti, E. Zito, J. Eiden, W. Gruber, E. Emini, K.U. Jansen eP135 13:12 Development and evaluation of Staphylococcus epidermidis DNA, mRNA and protein vaccines L. Yan* (Seattle, United States), J. Bryers eP132 13:18 A phase II study of the safety and immunogenicity of different formulations of a candidate Clostridium difficile toxoid vaccine: dose and formulation selection for phase III G. De Bruyn* (Swiftwater, United States), G. Foglia, J. Saleh, D. Workman, R. Pollak, R. Gesser eP139 13:24 Vaccination with a lipopolysaccharide-deficient inactivated whole cell vaccine provides protection against experimental Acinetobacter baumannii infection M. García Quintanilla* (Seville, Spain), J. Pachón Díaz, M.J. McConnell 84 24th ECCMID / Barcelona Final Programme eP145 13:42 FMD vaccine (Ronavac®) potency, stability, safety and efficacy test P. Zare, J. Shalmashi, O. Fakhri* (Tabriz, Iran), F. Ghaderi, Y. Farshi, S. Shadi eP131 13:48 The cost-effectiveness of vaccination against seasonal influenza in England M. Baguelin* (London, United Kingdom), A. Camacho, S. Flasche, J.W. Edmunds eP147 13:54 Development of an oral vaccine against candidiasis using molecular display technology S. Shibasaki* (Kobe, Japan), M. Ueda ePoster Sessions Monday, 12 May 2014 HALL I EPOSTER SESSION: Highlights from molecular mycology eP381 13:00 Use of PCR for diagnosis of invasive aspergillosis; a 3-year prospective cohort study H.C. Kung* (Taipei, Taiwan), Y.C. Chen, U.I. Wu, B.S. Ko, S.C. Chang eP384 13:06 Comparison of qPCR with bronchoalveolar lavage fluid and serum for the diagnosis of invasive pulmonary aspergillosis J. Yu* (Beijing, China), S. Zhang, R. Li eP385 13:12 Can genotyping discriminate between invasive and colonising Aspergillus fumigatus isolates? P. Escribano, T. Peláez, E. Bouza, J. Guinea Ortega* (Madrid, Spain) eP378 13:18 Is the frequency of Candida albicans epidemics and hyper-epidemic genotypes causing similar candidaemia in various European hospitals? L. Marcos-Zambrano, P. Escribano, M. Sanguinetti, E. Gomez G. de la Pedrosa, E. De Carolis, R. Cantón, E. Bouza, J. Guinea Ortega* (Madrid, Spain) eP394 13:36 Biofilm phenotypic and genotypic heterogeneity amongst Candida albicans bloodstream isolates differentially affects amphotericin B tolerance L. Sherry* (Glasgow, United Kingdom), R. Rajendran, B. Jones, C. Williams, C. Nile, G. Ramage eP390 13:42 Development of a new commercial qPCR assay to detect and differentiate dermatophyte infections of the skin, nails and hair G. Dingemans* (Maastricht, The Netherlands), M. Van den Bosch, M.P. Hayette, S. Goethel, V. Rusu, R. Sacheli, J. Meis, G. Gaajetaan, G. Simons eP392 13:48 Search strategy of new antifungal targets based on analysis of the protein domain and domain architecture content of fungal proteomes A. Barrera, A. Alastruey-Izquierdo* (Madrid, Spain), M. Martin, J.A. Vizcaino, I. Cuesta eP396 13:54 Measuring C. albicans and host gene expression during intra-abdominal candidiasis of humans and mice with RNA-Seq C.J. Clancy* (Pittsburgh, United States), S. Cheng, L. Losada, S. Mounaud, W. Nierman, N. Solis, S. Filler, W. Xu, A. Mitchell, M.H. Nguyen eP393 13:24 Multi-locus sequence typing of invasive and ePosters 13:00 – 14:00 Posters colonising Candida albicans isolates K. Heidrich, W. Buzina* (Graz, Austria), M. Hönigl, R. Krause eP397 13:30 The discordance between epidemiologically 24th ECCMID / Barcelona Final Programme 85 General Information Exhibition Chairs, Speakers & Authors related invasive and fluconazole resistant Candida tropicalis isolates highlight the necessity to further optimise C. tropicalis multilocus sequence typing X. Fan* (Beijing, China), M. Xiao, T.J. Gray, F.R. Kong, H. Wang, L. Zhang, Y.C. Xu IM PA CT CONTENTS THEME SECTION 845 Reviews The usefulness of whole genome sequencing in the management of Staphylococcus aureus infections J. Price, N. Claire Gordon, D. Crook, M. Llewelyn and J. Paul Advantages and limitations of genomics in prokaryotic taxonomy E. Sentausa and P.-E. Fournier Contact investigations for outbreaks of Mycobacterium tuberculosis: advances through whole genome sequencing T. M. Walker, P. Monk, E. Grace Smith and T. E. A. Peto Rapid bacterial genome sequencing: methods and applications in clinical microbiology C. Bertelli and G. Greub 784 790 796 803 INFECTIOUS DISEASES 822 829 E377 E386 831 E395 859 E398 BACTERIOLOGY 860 869 875 881 E405 882 E409 E412 E416 EPIDEMIOLOGY Original Articles Outbreak of Burkholderia cepacia bloodstream infections traced to the use of Ringer lactate solution as multiple-dose vial for catheter flushing, Phnom Penh, Cambodia B. De Smet, C. Veng, L. Kruy, C. Kham, J. van Griensven, C. Peeters, S. Ieng, T. Phe, E. Vlieghe, P. Vandamme and J. Jacobs Impact of a multimodal intervention to reduce bloodstream infections related to vascular catheters in non-ICU wards: a multicentre study N. Freixas, F. Bella, E. Limón, M. Pujol, B. Almirante and F. Gudiol 832 838 Evolution and aetiological shift of catheter-related bloodstream infection in a whole institution: the microbiology department may act as a watchtower M. Rodríguez-Créixems, P. Muñoz, P. Martín-Rabadán, E. Cercenado, M. Guembe and E. Bouza A multicentre analysis of epidemiology of the nosocomial bloodstream infections in Japanese university hospitals M. Nagao Abstract of Online-Only Original Article Molecular epidemiology of Staphylococcus aureus strains isolated from inpatients with infected diabetic foot ulcers in an Algerian University Hospital N. Djahmi, N. Messad, S. Nedjai, A. Moussaoui, D. Mazouz, J.–L. Richard, A. Sotto and J.–P. Lavigne E421 E424 Original Articles The changing epidemiology of bacteraemias in Europe: trends from the European Antimicrobial Resistance Surveillance System M. E. A. de Kraker, V. Jarlier, J. C. M. Monen, O. E. Heuer, N. van de Sande and H. Grundmann Fast determination of antibiotics in whole blood Q. Chen, A. Andersson, M. Mecklenburg and B. Xie Distribution of edin in Staphylococcus aureus isolated from diabetic foot ulcers N. Messad, L. Landraud, B. Canivet, G. Lina, J.-L. Richard, A. Sotto, J.-P. Lavigne, E. Lemichez and the French Study Group on the Diabetic Foot Abstract of Online-Only Original Article Sequences of multiple bacterial genomes and a Chlamydia trachomatis genotype from direct sequencing of DNA derived from a vaginal swab diagnostic specimen P. Andersson, M. Klein, R. A. Lilliebridge and P. M. Giffard Abstracts of Online-Only Research Notes Klebsiella pneumoniae harbouring OXA-48 carbapenemase in a Libyan refugee in Italy E. Kocsis, C. Savio, M. Piccoli, G. Cornaglia and A. Mazzariol Combined disc methods for the detection of KPC- and/or VIM-positive Klebsiella pneumoniae: improving reliability for the double carbapenemase producers V. Miriagou, E. Tzelepi, S. D. Kotsakis, G. L. Daikos, J. Bou Casals and L. S. Tzouvelekis Prevalence and spread of extended-spectrum β -lactamase-producing Enterobacteriaceae in Ngaoundere, Cameroon C. Lonchel Magoué, P. Melin, J. Gangoué-Piéboji, M.-C. Okomo Assoumou, R. Boreux and P. De Mol Emergence of Klebsiella pneumoniae co-producing NDM-type and OXA-181 carbapenemases M. N. D. Balm, M.-V. La, P. Krishnan, R. Jureen, R. T. P. Lin and J. W. P. Teo First detection in Europe of the metallo-β -lactamase IMP-15 in clinical strains of Pseudomonas putida and Pseudomonas aeruginosa R. Gilarranz, C. Juan, J. Castillo-Vera, F. J. Chamizo, F. Artiles, I. Álamo and A. Oliver E454 889 902 908 917 Editorial The return of the big three killers P. Parola 936 943 E428 E435 945 E443 E447 E451 948 955 961 E458 9 September 2013 IM Original Articles Modulation of potential respiratory pathogens by pH1N1 viral infection R. K.-K. Leung, J.-W. Zhou, W. Guan, S.-K. Li, Z.-F. Yang and S. K.-W. Tsui Factors associated with virological success with raltegravir-containing regimens and prevalence of raltegravir-resistance-associated mutations at failure in the ARCA database S. Rusconi, P. Vitiello, F. Adorni, B. Bruzzone, A. De Luca, V. Micheli, P. Meraviglia, R. Maserati, M. Di Pietro, G. Colao, G. Penco, A. Di Biagio, G. Punzi, L. Monno and M. Zazzi on behalf of the Antiretroviral Resistance Cohort Analysis Collaborative Group Abstracts of Online-Only Original Articles Accurate human papillomavirus genotyping by 454 pyrosequencing V. Militello, E. Lavezzo, G. Costanzi, E. Franchin, B. Di Camillo, S. Toppo, G. Palù and L. Barzon The significance of rhinovirus detection in hospitalized children: clinical, epidemiological and virological features J. C. Rahamat-Langendoen, A. Riezebos-Brilman, E. Hak, E. H. Schölvinck and H. G. M. Niesters Abstracts of Online-Only Research Notes Prevalence of etravirine (ETR)-RAMs at NNRTI failure and predictors of resistance to ETR in a large Italian resistance database (ARCA) S. Rusconi, F. Adorni, B. Bruzzone, A. Di Biagio, G. Meini, A. Callegaro, G. Punzi, E. Boeri, M. Pecorari, L. Monno, N. Gianotti, L. Butini, L. Galli, E. Polilli and M. Galli on behalf of the ARCA Collaborative Group Prognostic value of human papillomavirus types 16 and 18 DNA physical status in cervical intraepithelial neoplasia A. Gradíssimo Oliveira, C. Delgado, N. Verdasca and Â. Pista Detection of specific antibodies against West Nile and Usutu viruses in healthy blood donors in northern Italy, 2010–2011 A. Pierro, P. Gaibani, C. Spadafora, D. Ruggeri, V. Randi, S. Parenti, A. C. Finarelli, G. Rossini, M. P. Landini and V. Sambri FA techniques and their application in clinical CT OR microbiology :4 .57 8 CMI CLINICAL MICROBIOLOGY AND INFECTION the feasibility and usefulness of rapid dirty genomics in clinical microbiology. Right panel: Comparisons of three raw genomes sequences with corresponding whole genome sequences (missing DNA segments are shown in white). The green genome is that of Vibrio cholerae O1 strain 2010EL-1786 isolated during the Haiti Original Articles Predictive scoring model of mortalitycholera in Gram-negative outbreak. The brown genome is that of the Escherichia coli O104:H4 strain LB226692 isolated during bloodstream infection the German EHEC outbreak. The blue genome is that of the Parachlamydia acanthamoebae strain Hall coccus M. N. Al-Hasan, B. D. Lahr, J. E. Eckel-Passow andfrom L. M.the Baddour isolated water of an humidifier during the investigation of an outbreak of fever in a print shop in USA. Long-term mortality following bloodstream infection These three examples demonstrate that the dirty genome approach provides a significant proportion of all P. J. Lillie, J. Allen, C. Hall, C. Walsh, K.genomic Adams, sequence and supports the use of such rapid sequencing without gap closure for biomedical H. Thaker, P. Moss and G. D. Barlow applications. (images from C. Bertelli and G. Greub). Volume 19 Abstract of Online-Only Original Article Simultaneous detection of gastrointestinal pathogens with a multiplex Luminex-based molecular assay in stool samples from diarrhoeic patients C. Mengelle, J. M. Mansuy, M. F. Prere, E. Grouteau, I. Claudet, N. Kamar, A. Huynh, G. Plat, M. Benard, N. Marty, A. Valentin, A. Berry and J. Izopet EPIDEMIOLOGY 962 969 E466 Original Articles Healthcare-associated, community-acquired and hospital-acquired bacteraemic urinary tract infections in hospitalized patients: a prospective multicentre cohort study in the era of antimicrobial resistance J. P. Horcajada, E. Shaw, B. Padilla, V. Pintado, E. Calbo, N. Benito, R. Gamallo, M. Gozalo, J. Rodríguez-Baño, and other members of the ITUBRAS group, on behalf of Grupo de Estudio de Infección Hospitalaria (GEIH) and Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica (SEIMC) Abstract of Online-Only Original Article The use of dried cerebrospinal fluid filter paper spots as a substrate for PCR diagnosis of the aetiology of bacterial meningitis in the Lao PDR I. Elliott, S. Dittrich, D. Paris, A. Sengduanphachanh, P. Phoumin and P. N. Newton BACTERIOLOGY 970 975 980 988 E473 Original Articles Cohort study of the seasonal effect on nasal carriage and the presence of Mycobacterium leprae in an endemic area in the general population M. Lavania, R. P. Turankar, S. Karri, V. S. Chaitanya, U. Sengupta and R. S. Jadhav High prevalence of azithromycin resistance to Treponema pallidum in geographically different areas in China X.-S. Chen, Y.-P. Yin, W.-H. Wei, H.-C. Wang, R.-R. Peng, H.-P. Zheng, J.-P. Zhang, B.-Y. Zhu, Q.-Z. Liu and S.-J. Huang Microbiological changes and diversity in autochthonous non-toxigenic Corynebacterium diphtheriae isolated in France E. Farfour, E. Badell, S. Dinu, S. Guillot and N. Guiso Abstract of Online-Only Original Article Extrapulmonary infections caused by a dominant strain of Mycobacterium massiliense (Mycobacterium abscessus subspecies bolletii) A. Cheng, Y.-C. Liu, M.-L. Chen, C.-C. Hung, Y.-T. Tsai, W.-H. Sheng, C.-H. Liao, P.-R. Hsueh, Y.-C. Chen and S.-C. Chang THE OFFICIAL PUBLICATION OF THE EUROPEAN SOCIETY OF CLINICAL MICROBIOLOGY AND INFECTIOUS DISEASES Number 10 October 2013 1063 E483 THEME SECTION Editorial Foreseeing the future in infectious diseases: can we? Top Centre: Chest CT Scan of a 24-year old woman with XDR destructive pulmonary M. Paul tuberculosis E490 Top right: A mosquito vector of malaria, Anopheles dirus during a blood meal. Source: http://cdanofel.fr with Reviews permission 993 Modelling in infectious diseases: between haphazard and Bottom right: Images from a thin blood smear showing rings of Plasmodium falciparum (May-Grünwald hazard Giemsa; X1000). Source: http://cdanofel.fr with permission A. Neuberger, M. Paul, A. Nizar and D. Raoult Top and bottom left: 2 Schematic representations of HIV (Acknowledgments: Prof. Philippe Colson)and prediction in infectious 999 Mathematical modelling clm_v19_i10_oc.indd 1 1014 disease epidemiology A. Huppert and G. Katriel An overview of Internet biosurveillance D. M. Hartley, N. P. Nelson, R. R. Arthur, P. Barboza, N. Collier, N. Lightfoot, J. P. Linge, E. van der Goot, A. Mawudeku, L. C. Madoff, L. Vaillant, R. Walters, R. Yangarber, J. Mantero, C. D. Corley and J. S. Brownstein Modelling during an emergency: the 2009 H1N1 influenza pandemic B. Y. Lee, L. A. Haidari and M. S. Lee 1065 E499 1029 PARASITOLOGY 1035 1042 Original Articles Massive Plasmodium falciparum visceral sequestration: a cause of maternal death in Africa P. Castillo, C. Menéndez, A. Mayor, C. Carrilho, M. R. Ismail, C. Lorenzoni, F. Machungo, N. Osman, L. Quintó, C. Romagosa, C. Dobaño, P. L. Alonso and J. Ordi Rapid and sensitive diagnosis of Acanthamoeba keratitis by loop-mediated isothermal amplification Z. Ge, Y. Qing, S. Zicheng and S. Shiying EPIDEMIOLOGY 1049 Latest Impact Factor: 4.578 1058 IM Original Articles Predictive factors for mortality in patients with methicillin-resistant Staphylococcus aureus bloodstream infection: impact on outcome of host, microorganism and therapy O. Gasch, M. Camoez, M. A. Dominguez, B. Padilla, V. Pintado, B. Almirante, J. Molina, F. Lopez-Medrano, E. Ruiz, J. A. Martinez, E. Bereciartua, F. Rodriguez-Lopez, C. Fernandez-Mazarrasa, M. A. Goenaga, N. Benito, J. Rodriguez-Baño, E. Espejo, M. Pujol and on behalf of REIPI/GEIH Study Groups Single nucleotide polymorphisms typing of Mycobacterium leprae reveals focal transmission of leprosy in high endemic regions of India M. Lavania, R. S. Jadhav, R. P. Turankar, V. S. Chaitanya, M. Singh and U. Sengupta 1072 1078 1082 1089 E502 E509 1091 E516 E519 Original Articles Discrimination between Streptococcus pneumoniae and Streptococcus mitis based on sorting of their MALDI mass spectra L. N. Ikryannikova, A. V. Filimonova, M. V. Malakhova, T. Savinova, O. Filimonova, E. N. Ilina, V. A. Dubovickaya, S. V. Sidorenko and V. M. Govorun Human-associated Staphylococcus aureus strains within great ape populations in Central Africa (Gabon) PA CT FA CT CMI CLINICAL MICROBIOLOGY AND INFECTION Volume 19 Number 11 OR :4 .57 8 November 2013 9/6/2013 2:41:49 PM CMI CLINICAL MICROBIOLOGY AND INFECTION Editor-in-Chief: Didier Raoult Original Articles Chromoblastomycosis caused by Fonsecaea: clinicopathology, susceptibility and molecular identification of seven consecutive cases in southern China Y.-P. Yang, W. Li, W.-M. Huang, Y. Zhou and Y.-M. Fan Incidence of invasive fungal disease after unmanipulated haploidentical stem cell transplantation was significantly higher than that after HLA-matched sibling transplantation Y. Sun, L. Xu, D. Liu, X. Zhang, W. Han, Y. Wang, H. Chen, Y. Chen, F. Wang, J. Wang, Y. Ji, F. Tang, K. Liu and X.-J. Huang THE OFFICIAL PUBLICATION OF THE EUROPEAN SOCIETY OF CLINICAL MICROBIOLOGY AND INFECTIOUS DISEASES BACTERIOLOGY 1066 MYCOLOGY 1023 Abstracts of Online-Only Original Articles Season is associated with Pseudomonas aeruginosa acquisition in young children with cystic fibrosis K. J. Psoter, A. J. De Roos, J. Wakefield, J. Mayer and M. Rosenfeld Wastewater drainage system as an occult reservoir in a protracted clonal outbreak due to metallo-βlactamase-producing Klebsiella oxytoca S. Vergara-López, M. C. Domínguez, M. C. Conejo, Á. Pascual and J. Rodríguez-Baño Abstract of Online-Only Research Note Tuberculosis patients hospitalized in the Albert Schweitzer Hospital, Lambaréné, Gabon—a retrospective observational study S. M. Stolp, M. A. M. Huson, S. Janssen, J. O. Beyeme and M. P. Grobusch Volume 19 / Number 11 / November 2013 Editorial—Hot Topic Impact factors of scientific journals: the new season D. Raoult 991 1006 8/1/2013 1:28:47 PM Theme Section Editor: P. Parola: The Return of the Big Three Killers CONTENTS 989 M. Nagel, J. Dischinger, M. Türck, D. Verrier, M. Oedenkoven, B. Ngoubangoye, G. Le Flohic, J. F. Drexler, G. Bierbaum and J.-P. Gonzalez Interferon-γ release assays in the diagnosis of active tuberculosis disease in a low-incident setting: a 5-year review of data T. W. Lavender, A. Barrett, J. Magee and E. L. C. Ong Diversity in Acinetobacter baumannii isolates from paediatric cancer patients in Egypt L. Al-Hassan, H. El Mehallawy and S. G. B. Amyes Abstracts of Online-Only Original Articles Comparative performance of Thin Layer Agar and Löwenstein–Jensen culture for diagnosis of tuberculosis T. Battaglioli, N. Rintiswati, A. Martin, K. R. Palupi, G. Bernaerts, B. Dwihardiani, R. A. Ahmad, F. Matthys, Y. Mahendradhata and P. Van der Stuyft A nosocomial outbreak of KPC-2-producing Klebsiella pneumoniae in a Chinese hospital: dissemination of ST11 and emergence of ST37, ST392 and ST395 J. Yang, L. Ye, L. Guo, Q. Zhao, R. Chen, Y. Luo, Y. Chen, S. Tian, J. Zhao, D. Shen and L. Han Abstracts of Online-Only Research Notes Large IncHI2-plasmids encode extended-spectrum β-lactamases (ESBLs) in Enterobacter spp. bloodstream isolates, and support ESBL-transfer to Escherichia coli E. Nilsen, B. C. Haldorsen, A. Sundsfjord, G. S. Simonsen, A. Ingebretsen, U. Naseer, Ø. Samuelsen and the Norwegian Study Group on Invasive Enterobacter Chromosomal integration of the novel plasmid pUR3912 from methicillin-susceptible Staphylococcus aureus ST398 of human origin E. Gómez-Sanz, M. Zarazaga, K. Kadlec, S. Schwarz and C. Torres Theme Section Editor: M. Paul: Predictions on Infectious Diseases IM CONTENTS 1115 Reviews National Advisory Groups and their role in immunization policy-making processes in European countries H. Nohynek, O. Wichmann, F. D’Ancona and VENICE National Gatekeepers Guidelines for the treatment of pneumonia and urinary tract infections: evaluation of methodological quality using the Appraisal of Guidelines, Research and Evaluation II instrument O. Henig, D. Yahav, L. Leibovici and M. Paul Management and diagnostic guidelines for fungal diseases in infectious diseases and clinical microbiology: critical appraisal S. Leroux and A. J. Ullmann Abstracts of Online-Only Original Articles Roman carving Necrotizing soft tissue infections caused by Streptococcus Bottom left: Chicken voodoo. Source : http://www.thelocal.es/page/view/home/2013-03-19 pyogenes and Streptococcus dysgalactiae subsp. Bottom right : Example of mathematical modeling equisimilis of groups C and G in western Norway T. Bruun, B. R. Kittang, B. J. de Hoog, S. Aardal, H. K. Flaatten, N. Langeland, H. Mylvaganam, H. A. Vindenes and S. Skrede Serum antibody responses to pneumococcal colonization in the first 2 years of life: results from an SE Asian longitudinal cohort study P. Turner, C. Turner, N. Green, L. Ashton, E. Lwe, A. Jankhot, clm_v19_i11_oc.indd 1 N. P. Day, N. J. White, F. Nosten and D. Goldblatt E559 Oral bacterial community dynamics in paediatric patients with malignancies in relation to chemotherapy-related oral mucositis: a prospective study Y. Ye, G. Carlsson, M. Barr Agholme, J. A. L. Wilson, A. Roos, Volume B. Henriques-Normark, L. Engstrand, T. Modéer and K. Pütsep E551 BACTERIOLOGY VIROLOGY 1122 Original Articles Heparin-binding protein (HBP) in critically ill patients with influenza A (H1N1) infection K.-M. Kaukonen, R. Linko, H. Herwald, L. Lindbom, E. Ruokonen, T. Ala-Kokko and V. Pettilä Abstracts of Online-Only Original Articles Transmitted drug-resistance in human immunodeficiency virus-infected adult population in El Salvador, Central America Á. Holguín, G. Yebra, L. Martín, A. T. de Pineda, L. E. Ruiz, A. Y. Quezada, A. I. Nieto and G. Escobar Combining rapid diagnostic tests and dried blood spot assays for point-of-care testing of human immunodeficiency virus, hepatitis B and hepatitis C infections in Burkina Faso, West Africa D. Kania, A. M. Bekalé, N. Nagot, A.-M. Mondain, L. Ottomani, N. Meda, M. Traoré, J. B. Ouédraogo, J. Ducos, P. Van de Perre and E. Tuaillon Abstract of Online-Only Research Note Virological rebound in human immunodeficiency virus-infected patients with or without residual viraemia: results from an extended follow-up N. Gianotti, L. Galli, S. Salpietro, M. Cernuschi, S. Bossolasco, M. Maillard, V. Spagnuolo, F. Canducci, M. Clementi, A. Lazzarin and A. Castagna Clinical Microbiology and Infection is delighted to present these Special Issues: E533 1131 E542 1158 1163 1169 1173 E568 INFECTIOUS DISEASES 1132 1140 1148 Original Articles Epidemiology, risk factors and impact on long-term pancreatic function of infection following pancreas-kidney transplantation J. M. Herrero-Martínez, C. Lumbreras, A. Manrique, R. San-Juan, A. García-Reyne, F. López-Medrano, M. Lizasoain, B. de Dios, A. Andrés, C. Jiménez, E. Gutiérrez, E. Moreno and J. M. Aguado Enterococcal endocarditis in the beginning of the 21st century: analysis from the International Collaboration on Endocarditis-Prospective Cohort Study C. Chirouze, E. Athan, F. Alla, V. H. Chu, G. Ralph Corey, C. Selton-Suty, M.-L. Erpelding, J. M. Miro, L. Olaison, B. Hoen and on behalf of the International Collaboration on Endocarditis Study Group Invasive pneumococcal disease in patients with an underlying pulmonary disorder M. Inghammar, G. Engström, G. Kahlmeter, B. Ljungberg, C.-G. Löfdahl and A. Egesten Original Articles Evidence of transmission of a Panton–Valentine leukocidin-positive community-acquired methicillinresistant Staphylococcus aureus clone: a family affair P. Cocchi, G. Taccetti, C. Montagnani, S. Campana, L. Galli, C. Braggion and M. de Martino Vancomycin minimum inhibitory concentration, host comorbidities and mortality in Staphylococcus aureus bacteraemia N. E. Holmes, J. D. Turnidge, W. J. Munckhof, J. O. Robinson, T. M. Korman, M. V. N. O’Sullivan, T. L. Anderson, S. A. Roberts, S. J. C. Warren, W. Gao, P. D. R. Johnson and B. P. Howden Daptomycin non-susceptible Staphylococcus aureus at a US medical centre A. Velazquez, C. A. DeRyke, R. Goering, V. Hoover and M. R. Wallace Abstract of Online-Only Original Article Impact of rapid microbial identification directly from positive blood cultures using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry on patient management D. Martiny, F. Debaugnies, D. Gateff, M. Gérard, M. Aoun, C. Martin, D. Konopnicki, A. Loizidou, A. Georgala, M. Hainaut, M. Chantrenne, A. Dediste, O. Vandenberg and S. Van Praet FA CT 19 OR THE OFFICIAL PUBLICATION OF THE EUROPEAN SOCIETY OF CLINICAL MICROBIOLOGY AND INFECTIOUS DISEASES CMI CLINICAL MICROBIOLOGY AND INFECTION Number 12 :4 .57 8 10/3/2013 4:16:23 PM December 2013 CMI CLINICAL MICROBIOLOGY AND INFECTION 1129 E523 CT Top left : Tarot of Marseille. Source : http://lestarotsdejulia.e-monsite.com/pages/les-differents-tarots.html Top right: Achilles consulting Pythia, the priestess presiding over the Oracle of Apollo at Delphi. 1155 E545 EPIDEMIOLOGY 1174 1181 1188 E582 Original Articles An evaluation of clinical stability criteria to predict hospital course in community-acquired pneumonia A. R. Akram, J. D. Chalmers, J. K. Taylor, J. Rutherford, A. Singanayagam and A. T. Hill Small Indian mongooses and masked palm civets serve as new reservoirs of Bartonella henselae and potential sources of infection for humans S. Sato, H. Kabeya, Y. Shigematsu, H. Sentsui, Y. Une, M. Minami, K. Murata, G. Ogura and S. Maruyama Abstract of Online-Only Original Article Cost–benefit of infection control interventions targeting methicillin-resistant Staphylococcus aureus in hospitals: systematic review L. Farbman, T. Avni, B. Rubinovitch, L. Leibovici and M. Paul Theme Section Editor: M. Paul: Guidelines, consensus, expert opinions, analysis, meta-analysis: Who are the experts? How reliable are they? IM PA CT CONTENTS Cover images: CMI editorial report 2014 M. Leffad, R. Cousens and D. Raoult THEME SECTION Editorial 8 clm_v19_i12_oc.indd 1 Reviews 10 17 22 29 Measuring contact patterns with wearable sensors: methods, data characteristics and applications to data-driven simulations of infectious diseases A. Barrat, C. Cattuto, A. E. Tozzi, P. Vanhems and N. Voirin Web-based participatory surveillance of infectious diseases: the Influenzanet participatory surveillance experience D. Paolotti, A. Carnahan, V. Colizza, K. Eames, J. Edmunds, G. Gomes, C. Koppeschaar, M. Rehn, R. Smallenburg, C. Turbelin, S. Van Noort and A. Vespignani MediHandTrace®: a tool for measuring and understanding hand hygiene adherence S. Boudjema, J. C. Dufour, A. S. Aladro, I. Desquerres and P. Brouqui New technologies to monitor healthcare worker hand hygiene A. R. Marra and M. B. Edmond Reviews 101 114 123 51 O2 Dissemination of bla VIM in Greece at the peak of the epidemic of 2005–2006: clonal expansion of Klebsiella pneumoniae clonal complex 147 C. M. Hasan, A. Turlej-Rogacka, A. C. Vatopoulos, P. Giakkoupi, M. Maâtallah and C. G. Giske Knowledge, attitudes, beliefs and practices of general practitioners towards measles and MMR vaccination in southeastern France in 2012 C. Pulcini, S. Massin, O. Launay and P. Verger Epidemiological investigation of a nosocomial outbreak of multidrug-resistant Corynebacterium striatum at one Belgian university hospital A. Verroken, C. Bauraing, A. Deplano, P. Bogaerts, D. Huang, G. Wauters and Y. Glupczynski Abstract of Online-Only Research Note Clostridium difficile PCR ribotype 046 is common among neonatal pigs and humans in Sweden T. Norén, K. Johansson and M. Unemo BACTERIOLOGY 136 152 075 Risk factors for superficial wound complications in hip and knee arthroplasty K. Carroll, M. Dowsey, P. Choong and T. Peel Does a rapid diagnosis of Clostridium difficile infection impact on quality of patient management? F. Barbut, L. Surgers, C. Eckert, B. Visseaux, M. Cuingnet, C. Mesquita, N. Pradier, A. Thiriez, N. Ait-Ammar, A. Aifaoui, E. Grandsire and V. Lalande Incidence, clinical characteristics and 30-day mortality of enterococcal bacteraemia in Denmark 2006–2009: a population-based cohort study M. Pinholt, C. Østergaard, M. Arpi, N. E. Bruun, H. C. Schønheyder, K. O. Gradel, M. Søgaard and J. D. Knudsen for the Danish Collaborative Bacteraemia Network (DACOBAN) Abstract of Online-Only Original Article Update on treatment options for spinal brucellosis A. Ulu-Kilic, A. Karakas, H. Erdem, T. Turker, A. S. Inal, O. Ak, H. Turan, E. Kazak, A. Inan, F. Duygu, H. Demiraslan, C. Kader, A. Sener, S. Dayan, O. Deveci, R. Tekin, N. Saltoglu, M. Aydın, E. S. Horasan, H. C. Gul, B. Ceylan, A. Kadanalı, O. Karabay, G. Karagoz, U. Kayabas, V. Turhan, D. Engin, S. Gulsun, N. Elaldı and S. Alabay 153 159 O83 Evaluation of two matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) systems for the identification of Candida species C. Lacroix, A. Gicquel, B. Sendid, J. Meyer, I. Accoceberry, N. François, F. Morio, G. Desoubeaux, J. Chandenier, C. Kauffmann-Lacroix, C. Hennequin, J. Guitard, X. Nassif and M.-E. Bougnoux Abstract of Online-Only Original Article Epidemiological study of a large cluster of fungaemia cases due to Kodamaea ohmeri in an Indian tertiary care centre A. Chakrabarti, S. M. Rudramurthy, P. Kale, P. Hariprasath, M. Dhaliwal, S. Singhi and K. L. N. Rao VIROLOGY Original Articles 160 Risk factors of Ganciclovir-related neutropenia after allogeneic stem cell transplantation: a retrospective monocentre study on 547 patients G. Venton, R. Crocchiolo, S. Fürst, A. Granata, C. Oudin, C. Faucher, D. Coso, R. Bouabdallah, P. Berger, N. Vey, P. Ladaique, C. Chabannon, M. le Merlin, D. Blaise and J. El-Cheikh O39 VIROLOGY 91 O47 59 65 70 79 Serotypes, genotypes and antimicrobial resistance patterns of human diarrhoeagenic Escherichia coli isolates circulating in southeastern China Y. Chen, X. Chen, S. Zheng, F. Yu, H. Kong, Q. Yang, D. Cui, N. Chen, B. Lou, X. Li, L. Tian, X. Yang, G. Xie, Y. Dong, Z. Qin, D. Han, Y. Wang, W. Zhang, Y.-W. Tang and L. Li Mycobacterium leprae is identified in the oral mucosa from paucibacillary and multibacillary leprosy patients M. A. M. Morgado de Abreu, A. M. Roselino, M. Enokihara, S. Nonogaki, L. E. Prestes-Carneiro, L. L. M. Weckx and M. M. A. Alchorne Comparison of testing approaches for Clostridium difficile infection at a large community hospital J. D. Grein, M. Ochner, H. Hoang, A. Jin, M. A. Morgan and A. R. Murthy Patient nostril microbial flora: individual-dependency and diversity precluding prediction of Staphylococcus aureus acquisition A. S. Alvarez, L. Remy, C. Allix-Béguec, C. Ligier, C. Dupont, O. Leminor, C. Lawrence, P. Supply, D. Guillemot, J. L. Gaillard, J. Salomon and J.-L. Herrmann Abstracts of Online-Only Original Articles 174 Impact of carbapenem resistance on clinical and economic outcomes among patients with Acinetobacter baumannii infection in Colombia E. V. Lemos, F. P. de la Hoz, N. Alvis, T. R. Einarson, E. Quevedo, C. Castañeda, Y. Leon, C. Amado, O. Cañon and K. Kawai Abstracts of Online-Only Original Articles Prevalence and characterization of extended-spectrum β-lactamase-producing clinical Salmonella enterica isolates in Dakar, Senegal, from 1999 to 2009 D. Harrois, S. Breurec, A. Seck, A. Delauné, S. Le Hello, M. Pardos de la Gándara, L. Sontag, J.-D. Perrier-Gros-Claude, J.-M. Sire, B. Garin and F.-X. Weill Infections caused by carbapenem-resistant Klebsiella pneumoniae among patients in intensive care units in Greece: a multi-centre study on clinical outcome and therapeutic options F. Kontopidou, H. Giamarellou, P. Katerelos, A. Maragos, I. Kioumis, E. Trikka-Graphakos, C. Valakis and H. C. Maltezou on behalf of the Group for the Study of KPC-producing Klebsiella pneumoniae infections in intensive care units Genome-wide single nucleotide polymorphism-based assay for high-resolution epidemiological analysis of the methicillin-resistant Staphylococcus aureus hospital clone EMRSA-15 A. Holmes, G. McAllister, P. R. McAdam, S. Hsien Choi, K. Girvan, A. Robb, G. Edwards, K. Templeton and J. R. Fitzgerald Abstract of Online-Only Research Note KPC-2 and OXA-48 carbapenemase-harbouring Enterobacteriaceae detected in an Austrian wastewater treatment plant H. Galler, G. Feierl, C. Petternel, F. F. Reinthaler, D. Haas, A. J. Grisold, J. Luxner and G. Zarfel BACTERIOLOGY Original Articles 181 O109 O117 184 O132 Volume 20 Number Abstracts of Online-Only Research Note Changing aetiology of hand, foot and mouth disease in Linyi, China, 2009–2011 J. Du, X. Wang, Y. Hu, Z. Li, Y. Li, S. Sun, F. Yang and Q. Jin 058 OR :4 .57 8 1 January 2014 Abstracts of Online-Only Original Articles A prospective, cohort, multicentre study of candidaemia in hospitalized adult patients with haematological malignancies M. N. Gamaletsou, T. J. Walsh, T. Zaoutis, M. Pagoni, M. Kotsopoulou, M. Voulgarelis, P. Panayiotidis, T. Vassilakopoulos, M. K. Angelopoulou, M. Marangos, A. Spyridonidis, D. Kofteridis, A. Pouli, D. Sotiropoulos, P. Matsouka, A. Argyropoulou, S. Perloretzou, K. Leckerman, A. Manaka, P. Oikonomopoulos, G. Daikos, G. Petrikkos and N. V. Sipsas Survival of influenza virus on human fingers Y. Thomas, P. Boquete-Suter, D. Koch, D. Pittet and L. Kaiser PARASITOLOGY 94 O65 95 O72 96 Abstracts of Online-Only Original Article Detection of Cryptosporidium and Giardia in clinical laboratories in Europe—a comparative study M. Manser, M. Granlund, H. Edwards, A. Saez, E. Petersen, B. Evengard and P. Chiodini on behalf of the European Society of Clinical Microbiology and Infectious Diseases Study Group on Clinical Parasitology Abstracts of Online-Only Research Note Saliva as a source of anti-Toxoplasma gondii IgG for enzyme immunoassay in human samples B. F. C. Sampaio, M. S. Macre, L. R. Meireles and H. F. Andrade Jr Corrigendum Theme Section Editor: P. Brouqui: Emerging technology in tracking contagion IM PA Cover images: Molecular characterization of methicillin-resistant Staphylococcus aureus isolated over a 2-year period in a Qatari hospital from multinational patients T. S. El-Mahdy, M. El-Ahmady and R. V. Goering CT 11/5/2013 2:10:12 PM CT Top Left: Contact pattern network; source: Alain Barrat Centre: Medihand equipped room; source: Philippe Brouqui EPIDEMIOLOGY Original Article FA CMI CLINICAL MICROBIOLOGY AND INFECTION MYCOLOGY 92 O50 Original Articles 52 169 O124 MYCOLOGY Original Articles 89 O33 Global impact of an educational antimicrobial stewardship programme on prescribing practice in a tertiary hospital centre J. M. Cisneros, O. Neth, M. V. Gil-Navarro, J. A. Lepe, F. Jiménez-Parrilla, E. Cordero, M. J. Rodríguez-Hernández, R. Amaya-Villar, J. Cano, A. Gutiérrez-Pizarraya, E. García-Cabrera and J. Molina, PRIOAM team Abstracts of Online-Only Original Articles Streptococcal vertebral osteomyelitis: multiple faces of the same disease O. Murillo, A. Roset, B. Sobrino, J. Lora-Tamayo, R. Verdaguer, E. Jiménez-Mejias, J. M. Nolla, J. de. D. Colmenero and J. Ariza Enhanced antimicrobial activity of peptide-cocktails against common bacterial contaminants of ex vivo stored platelets K. V. K. Mohan, S. Sainath Rao, Y. Gao and C. D. Atreya Top Right: Wearable sensor, source: Alain Barrat Abstract of Online-Only Original Article Bottom HCW pathway; source: Philippe Brouqui A comparison of efficacy and safety of 2-yearLeft: telbivudine Bottom Right: Nurse backscreen information Medihand; source: Philippe Brouqui and entecavir treatment in patients with chronic hepatitis B: a match–control study M.-C. Tsai, C.-H. Chen, C.-H. Hung, C.-M. Lee, K.-W. Chiu, J.-H. Wang, S.-N. Lu, P.-L. Tseng, K.-C. Chang, Y.-H. Yen and T.-H. Hu 168 Abstracts of Online-Only Research Notes O101 First detection of Toscana virus in Corsica, France L. Bichaud, A. Izri, X. de Lamballerie, G. Moureau and R. N. Charrel 1 clm_v20_i1_oc.indd O105 Predictors of H1N1 influenza in the emergency department: proposition for a modified H1N1 case definition H. Flick, M. Drescher, J. Prattes, K. Tovilo, H. H. Kessler, K. Vander, K. Seeber, M. Palfner, R. B. Raggam, A. Avian, R. Krause and M. Hoenigl INFECTIOUS DISEASES Original Articles 130 145 INFECTIOUS DISEASES Original Articles 82 Original Articles 44 THE OFFICIAL PUBLICATION OF THE EUROPEAN SOCIETY OF CLINICAL MICROBIOLOGY AND INFECTIOUS DISEASES CMI CLINICAL MICROBIOLOGY AND INFECTION Volume 20 Number 2 FA CT OR :4 .57 8 12/10/2013 12:09:44 PM February 2014 CMI CLINICAL MICROBIOLOGY AND INFECTION • ESCMID Update of the Treatment Guidance Document for Clostridium difficile Infection 105 Systematic reviews and meta-analyses in infectious diseases: topics that merit special attention L. Leibovici, D. Yahav and M. Paul Systematic reviews and meta-analyses of diagnostic test accuracy M. M. G. Leeflang Antiretroviral therapy for initial human immunodeficiency virus/AIDS treatment: critical appraisal of the evidence from over 100 randomized trials and 400 systematic reviews and meta-analyses S. Kanters, E. J. Mills, K. Thorlund, H. C. Bucher and J. P. A. Ioannidis The effects of clinical and statistical heterogeneity on the predictive values of results from meta-analyses W. G. Melsen, M. C. J. Bootsma, M. M. Rovers and M. J. M. Bonten O30 EPIDEMIOLOGY 34 38 167 O90 Systematic review or meta-analysis? Their place in the evidence hierarchy M. Paul and L. Leibovici 81 O27 An 8-year survey of strains identified in blood cultures in a clinical haematology unit A. Bousquet, J.-V. Malfuson, N. Sanmartin, J. Konopacki, C. MacNab, B. Souleau, T. de Revel, M. Elouennass, T. Samson, C. Soler, V. Foissaud and C. Martinaud Dual infections with different Legionella strains G. Wewalka, D. Schmid, T. G. Harrison, S. A. Uldum and C. Lück on behalf of the European Society of Clinical Microbiology Infectious Diseases Study Group for Legionella Infections (ESGLI) Four-year epidemiological study of extended-spectrum β-lactamase-producing Enterobacteriaceae in a French teaching hospital L. Gibold, F. Robin, R.-N. Tan, J. Delmas and R. Bonnet Abstracts of Online-Only Research Notes Emergence of VIM-4 metallo-β-lactamase-producing Klebsiella pneumoniae ST15 clone in the Clinical Centre University of Pécs, Hungary S. Melegh, K. Kovács, T. Gám, A. Nyul, B. Patkó, Á. Tóth, I. Damjanova and G. Mestyán Acremonium sclerotigenum-Acremonium egyptiacum: a multi-resistant fungal pathogen complicating the course of aplastic anaemia J. Guitard, A. Degulys, G. Buot, A. Aline-Fardin, E. Dannaoui, B. Rio, J. P. Marie, S. Lapusan and C. Hennequin Volume 20 / Number 2 / February 2014 THEME SECTION Editorial O20 New technologies to trace infection P. Brouqui CONTENTS 97 O13 CMI CLINICAL MICROBIOLOGY AND INFECTION • ESCMID Guidelines for the Management of the Infection Control Measures to Reduce Transmission of Multidrugresistant Gram-negative Bacteria in Hospitalized Patients O7 Editorial 1 Volume 20 / Number 1 / January 2014 INFECTION HOT TOPIC Top Left: Alice’s Adventures in Wonderland: A Mad Tea Party. (Source: Wikicommons) Bottom Left: The Moneylender and his Wife. Quentin Matsys, 1514.O1 From the Hajj: it’s the flu, idiot R. Charrel, P. Gautret and P. Parola Right: Plato’s Academy mosaic — from the Villa of T. Siminius Stephanus D. inRaoult, Pompeii. PARASITOLOGY 185 O135 O139 Theme Section Editor: M. Paul: Systematic reviews and meta-anaylses in infectious diseases Abstracts of Online-Only Research Notes A family cluster of giardiasis with variable treatment responses: refractory giardiasis in a family after a trip to India A. Requena-Méndez, P. Goñi, S. Lóbez, I. Oliveira, E. Aldasoro, M.-E. Valls, A. Clavel, J. Gascón and J. Muñoz Molecular survey of knockdown resistance to pyrethroids in human scabies mites V. Andriantsoanirina, A. Izri, F. Botterel, F. Foulet, O. Chosidow and R. Durand IM PA Cover images: J. McConnell and D. Raoult THEMED SECTION Editorial 189 Microbe discovery: lessons from the past M. Drancourt Reviews clm_v20_i2_oc.indd 1 EPIDEMIOLOGY Original Articles 219 Clinical and epidemiological characterization of a lymphogranuloma venereum outbreak in Madrid, Spain: co-circulation of two variants M. Rodríguez-Domínguez, T. Puerta, B. Menéndez, J. M. González-Alba, C. Rodríguez, T. Hellín, M. Vera, F. J. González-Sainz, P. Clavo, M. Villa, R. Cantón, J. Del Romero and J. C. Galán 226 Abstract of Online-Only Original Article O142 Single nucleotide polymorphism-based molecular typing of M. leprae from multicase families of leprosy patients and their surroundings to understand the transmission of leprosy R. P. Turankar, M. Lavania, V. S. Chaitanya, U. Sengupta, J. Darlong, F. Darlong, K. S. R. Siva Sai and R. S. Jadhav VIROLOGY Original Articles 227 The relationship between tumour necrosis factor-α gene polymorphism and susceptibility and clearance of the persistent hepatitis B virus infection in a Chinese population: a meta-analysis T.-C. Zhang, Y.-Q. Zhao, G.-L. Hu, X.-Q. Liu and X.-K. Huang 235 Viral load and humoral immune response in association with disease severity in Puumala hantavirus-infected patients—implications for treatment L. Pettersson, T. Thunberg, J. Rocklöv, J. Klingström, M. Evander and C. Ahlm 242 Abstracts of Online-Only Original Articles O150 Molecular epidemiology of enterovirus 71, coxsackievirus A16 and A6 associated with hand, foot and mouth disease in Spain M. Cabrerizo, D. Tarragó, C. Muñoz-Almagro, E. del Amo, M. Domínguez-Gil, J. Mª Eiros, I. López-Miragaya, C. Pérez, J. Reina, A. Otero, I. González, J. E. Echevarría and G. Trallero INFECTIOUS DISEASE Original Articles 246 Inadequate management of pregnancy-associated listeriosis: lessons from four case reports C. Charlier, F. Goffinet, E. Azria, A. Leclercq and M. Lecuit 250 Abstract of Online-Only Original Article O182 Added value of multiplex Luminex Gastrointestinal Pathogen Panel (xTAG® GPP) testing in the diagnosis of infectious gastroenteritis E. Wessels, L. G. Rusman, M. J. A. W. M. van Bussel and E. C. J. Claas BACTERIOLOGY Original Articles 251 Extended-spectrum β-lactamase producing Klebsiella spp. in chicken meat and humans: a comparison of typing methods I. T. M. A. Overdevest, M. Heck, K. van der Zwaluw, X. Huijsdens, M. van Santen, M. Rijnsburger, A. Eustace, L. Xu, P. Hawkey, P. Savelkoul, C. VandenbrouckeGrauls, I. Willemsen, J. van der Ven, C. Verhulst and J. A. J. W. Kluytmans 256 Mycobacterium avium genotype is associated with the therapeutic response to lung infection T. Kikuchi, Y. Kobashi, T. Hirano, N. Tode, A. Santoso, T. Tamada, S. Fujimura, Y. Mitsuhashi, Y. Honda, T. Nukiwa, M. Kaku, A. Watanabe and M. Ichinose 263 Mycobacterium tuberculosis bacteraemia: experience from a non-endemic urban centre H. M. El Sahly, L. D. Teeter, J. M. Musser and E. A. Graviss 269 Abstracts of Online-Only Original Articles O188 Exposure to ertapenem is possibly associated with Pseudomonas aeruginosa antibiotic resistance M. J. Cohen, C. S. Block, A. E. Moses and R. Nir-Paz O197 Mediastinitis due to Gram-negative bacteria is associated with increased mortality H. Charbonneau, J. M. Maillet, M. Faron, O. Mangin, E. Puymirat, P. Le Besnerais, L. Du Puy-Montbrun, P. Achouh, J. L. Diehl, J.-Y. Fagon, J.-L. Mainardi and E. Guerot 271 Abstract of Online-Only Research Note 0203 Mobile genetic elements of Pseudomonas aeruginosa isolates from hydrotherapy facility and respiratory infections S. G. Pereira and O. Cardoso 272 Erratum CMI CLINICAL MICROBIOLOGY AND INFECTION FA CT OR :4 .57 8 1/9/2014 6:21:53 PM Volume 20 Number 3 March 2014 CMI CLINICAL MICROBIOLOGY AND INFECTION 191 The greatest steps towards the discovery of Vibrio cholerae D. Lippi and E. Gotuzzo 196 Steps towards the discovery of Mycobacterium tuberculosis by Robert Koch, 1882 E. Cambau and M. Drancourt 202 Plague history: Yersin’s discovery of the causative bacterium in 1894 enabled, in the subsequent century, scientific progress in understanding the disease and the development of treatments and vaccines T. Butler 210 The rediscovery of smallpox C. Thèves, P. Biagini and E. Crubézy CT O157 Quasispecies tropism and compartmentalization in gut and peripheral blood during early and chronic phases of HIV-1 infection: possible correlation with immune activation markers G. Rozera, I. Abbate, C. Vlassi, E. Giombini, R. Lionetti, M. Selleri, P. Zaccaro, B. Bartolini, A. Corpolongo, G. D’Offizi, A. Baiocchini, F. Del Nonno, G. Ippolito and M. R. Capobianchi O167 Clinical significance of intra-host variability of Dengue-1 virus in venous and capillary blood E. Descloux, C. La Fuentez, Y. Roca and X. De Lamballerie 245 Abstract of Online-Only Research Note 0176 Increased incidence of acute parvovirus B19 infections in Marseille, France, in 2012 compared with the 2002–2011 period S. Aherfi, L. Ninove, C. Zandotti, P. Crepey, H. Richet, A. Nougairede, X. de Lamballerie and R. N. Charrel Volume 20 / Number 3 / March 2014 C OWikimedia N T E N Tcommons, S Top: Weighing the heart, From Thebes, Egypt 19th Dynasty, around 1275 BC, source: public domain. Bottom Left: Clinical malaria among children receiving iron +/- folic acid versus placebo or no treatment in randomized controlled trials. Analysis sub-grouped by settings with or without malaria surveillance and treatment services, showing divergence of results. Re-generated from data in Okebe et al. Oral iron supplements for childrenHot in malaria-endemic areas. Infection Topic Cochrane Database Syst Rev. 2011 Oct 5;( 10):CD006589. 187 Emerging respiratory viruses: is it ‘much ado about Bottom Right: The pyramid of evidence-based medicine. Source: M. Paul. nothing’? (Shakespeare) Theme Section Editor: M. Drancourt: Microbe discovery: lessons from the past 14-64530 1106 Editorial Guidelines in infectious diseases: how reliable are they? M. Paul, E. Roilides and P. T. Tassios Volume 19 / Number 12 / December 2013 1096 PA Cover images: THEMED SECTION 1093 •Pneumococcal Conjugate Vaccines .54 0 clm_v19_i9_oc.indd 1 Cover images: 2012 ISI Journal Citation Reports® Number :4 CMI CLINICAL MICROBIOLOGY AND INFECTION Reviews The re-emergence of tuberculosis: what have we learnt from molecular epidemiology? M. W. Borgdorff and D. van Soolingen The changes in mosquito vector behaviour and the emerging resistance to insecticides will challenge the decline of malaria C. Sokhna, M. O. Ndiath and C. Rogier Fighting drug-resistant Plasmodium falciparum: the challenge of artemisinin resistance C. Wongsrichanalai and C. H. Sibley The emerging and re-emerging human immunodeficiency virus epidemics in Europe I. Bozicevic, S. Handanagic, S. Z. Lepej and J. Begovac INFECTIOUS DISEASES VIROLOGY 930 19 Co-infections with hepatitis B and C viruses in human immunodeficiency virus-infected patients in Morocco Cover images: K. Rebbani, A. Ouladlahsen, A. Bensghir, A. Akil, H. Lamdini, Genomics of medical importance. Left panel: Increasing number of genomes sequenced from 1995 to 2012; H. Issouf, I. Brahim, B. Kitab, F. Z. Fakhir, L. Wakrim, please note that genomics progressively shifted from complete genomes to draft genomes allowing reduced K. Marhoum El Filali, H. Himmich, S. Ezzikouri S. Benjelloun time toand results; the genome of the EHEC strain isolated from the German outbreak of May 2011 demonstrated Volume 19 / Number 10 / October 2013 Yellow fever revaccination guidelines change – a decision too feverish? M. P. Grobusch, A. Goorhuis, R. W. Wieten, J. D. M. Verberk, E. F. F. Jonker, P. J. J. van Genderen and L. G. Visser THEME SECTION 887 Volume OR P INFECTION HOT TOPIC The authoritative source of information across the fields of microbiology and infectious disease CT AC Theme Section Editors: G.Greub & P. E. Fournier: T Genomics in routine diagnostic labs - new CONTENTS 885 FA CMI CLINICAL MICROBIOLOGY AND INFECTION CMI CLINICAL MICROBIOLOGY AND INFECTION Original Articles Mapping ongoing European research activities examining the infectious aetiology of chronic conditions J. C. Semenza, I. Svederud, E. Medin, S. Orrskog and S. Tsolova Prospective survey of acute osteoarticular infections in a French paediatric orthopedic surgery unit A. Ferroni, H. Al Khoury, C. Dana, G. Quesne, P. Berche, C. Glorion and Z. Péjin Abstracts of Online-Only Original Articles Current management of patients hospitalized with complicated skin and soft tissue infections across Europe (2010–2011): assessment of clinical practice patterns and real-life effectiveness of antibiotics from the REACH study J. Garau, H. Ostermann, J. Medina, M. Ávila, K. McBride and F. Blasi, on behalf of the REACH study group The cultivable human oral gluten-degrading microbiome and its potential implications in coeliac disease and gluten sensitivity M. Fernandez-Feo, G. Wei, G. Blumenkranz, F. E. Dewhirst, D. Schuppan, F. G. Oppenheim and E. J. Helmerhorst Abstract of Online-Only Research Note Asymptomatic brucellosis infection in humans: implications for diagnosis and prevention Q. Zhen, Y. Lu, X. Yuan, Y. Qiu, J. Xu, W. Li, Y. Ke, Y. Yu, L. Huang, Y. Wang and Z. Chen 814 852 Volume 19 / Number 9 / September 2013 Editorial Genomics of medical importance G. Greub 781 Cover images: Clockwise from bottom right Figure 1: Jean Antoine Villemin; source: Wikipedia Figure 2: J. A. Villemin thesis; source: Bibliotheque Numérique Medica (http://www2.biusante.parisdescartes.fr/livanc/index.las?cote=34844&p=4&do=page) Figure 3: Robert Koch; source: Wikipedia Figure 4: R. Koch’s tuberculosis paper; source: Google Figure 5: First M. Tuberculosis isolate; source: Hunterian Museum, Royal College of Surgeons, London Figure 6: Mycobacterium tuberculosis; source: Michel Drancourt. clm_v20_i3_oc.indd 1 www.cmijournal.com 2/7/2014 12:08:54 PM ePoster Viewing Saturday, 10 May 2014 - Tuesday, 13 May 2014 eP008 Population pharmacokinetics of ceftazidime and cefepime in septic shock patients during continuous renal replacement therapy M. Carlier* (Ghent, Belgium), F. Taccone, L. Seyler, F. Jacobs, M. Beumier, J.L. Vincent, J. Lipman, J. Roberts eP009 Explaining variability in gentamicin peak concentrations to optimise gentamicin dosing in critically ill patients R.M. Van Hest* (Amsterdam, The Netherlands), C.S.C. Bouman, C.E. Visser, N.P. Juffermans, C.J. Hodiamont, R.A. Mathot eP010 Amikacin peak loading in obese patients: application of adjusted body weight formula with modern posologies. Are 30 mg/kg enough? C. Lu, M. Meddour, N. Van Grunderbeeck* (Lens, France), M. Nyunga, M. Boyer-Besseyre, J. Gois, E. Parmentier-Decrucq, J. Mallat, D. Thevenin, N. Lemaire EPOSTER VIEWING: PK/PD to improve treatment of critically ill patients eP004 How do changes in settings of renal replacement therapies in critically ill patients change the pharmacokinetics of piperacillin, meropenem and vancomycin? J.A. Jamal* (Brisbane, Australia), A.A. Udy, J. Lipman, J.A. Roberts Pharmacokinetic/pharmacodynamic evaluation of the efficacy and cost-effectiveness of various carbapenem dosing regimens for the treatment of Gram-negative bacterial bloodstream infections T.P. Lim, Y. Cai, J. Teo, Z.W. Wang, W. Lee, T.Y. Tan, T.T. Tan, L.Y. Hsu, T.H. Koh, A. Kwa* (Singapore, Singapore) eP005 The effect of extracorporeal membrane oxygenation in critically ill patients on meropenem pharmacokinetics: a matched cohort study J. Roberts* (Brisbane, Australia), K. Shekar, J. Fraser, D. Mullany, S. Wallis, J. Lipman eP006 Comparative evaluation of the accuracy and precision of pharmacokinetic equations to predict free meropenem concentrations in critically ill patients A. Farkas, G. Wong, G. Daroczi, J. Lipman, J. Roberts* (Queensland, Australia) eP007 Microdialysis tissue pharmacokinetics and pharmacokinetic-pharmacodynamic modelling of ertapenem after 1g/12h administrations to critically ill patients N. Gregoire* (Poitiers, France), N. Hamitouche, L. Laksiri, T. Loupec, S. Marchand, O. Mimoz, W. Couet Viewing Stations EPOSTER VIEWING: Carbapenem and quinolone resistance in Enterobacteriaceae eP011 Prevalence of carbapenem-resistant organisms in German ICUs: first results from the national nosocomial infection surveillance system (KISS) F. Maechler* (Berlin, Germany), L. Pena Diaz, C. Geffers, M. Behnke, P. Gastmeier eP012 Epidemiology and predictors of IMP-type metallobeta-lactamase-producing Enterobacter cloacae isolation in a tertiary medical centre: a casecontrol study K. Hayakawa* (Tokyo, Japan), T. Miyoshi-Akiyama, S. Kubota, E. Kuroda, Y. Sugiki, M. Nagamatsu, N. Takeshita, S. Kutsuna, T. Kirikae, N. Ohmagari eP013 An outbreak caused by carbapenem-resistant Serratia marcescens (SME) clinical isolates coproducing KPC-2 and IMP-10 in a tertiary teaching hospital in Brazil K.E. Silva, C. Carvalhaes, R. Cayô* (São Paulo, Brazil), F. Rodrigues-Costa, F. Patussi, J.H.R. Croda, F.J. Negrão, A.C. Gales, S. Simionatto 24th ECCMID / Barcelona Final Programme 87 ePosters eP003 Impact of beta-lactam pharmacokinetics/ pharmacodynamics on clinical outcome of bloodstream infections in critically ill patients M. Nunez-Nunez* (Seville, Spain), G. Wong, S.C. Wallis, B. McWhinney, J.P.G. Ungerer, J. Mayer, J. Lipman, J.A. Roberts Posters eP002 Population probability of target attainment of colistin at different levels of renal function against Pseudomonas aeruginosa and Acinetobacter baumannii in Europe A. Farkas, K. Hoffman, C. Levy, J. Roberts* (Queensland, Australia) Chairs, Speakers & Authors eP001 Exhibition Viewing Stations General Information ePoster Viewing Saturday, 10 May 2014 - Tuesday, 13 May 2014 eP014 The host bacterial-plasmid network: observations of Klebsiella pneumoniae-carbapenemase (KPC) gene mobility in a K. pneumoniae cohort using whole genome sequencing A.J. Mathers* (Charlottesville, United States), N. Stoesser, A.E. Sheppard, A. Geiss, X. Didelot, C.D. Sifri, D.W. Crook eP023 Sequence types of Staphylococcus epidermidis associated with prosthetic joint infections are not present in the laminar air flow during prosthetic joint surgery E. Månsson* (Västerås, Sweden), B. Hellmark, M. Sundqvist, B. Söderquist eP015 Characterisation of carbapenem-resistant Enterobacteriaceae isolated in four countries of the Arabian peninsula T. Pal* (Al Ain, United Arab Emirates), A. Sonnevend, A. Ghazawi, D. Darwish, R. Hashmey, W. Jamal, V. Rotimi, A. Al-Jardani, S. Al-Abri, A. Shibl eP024 Computer-enhanced surveillance of surgical site infections: early assessment of a generalisable method for French hospitals B. Leclère, C. Lasserre, C. Bourigault, M.E. Juvin, M.P. Chaillet, M. Hanf, J. Caillon, D. Lepelletier* (Nantes, France) eP016 Prevalence and characterisation of quinolone resistance mechanisms in indicator Escherichia coli D. Wasyl* (Pulawy, Poland), A. Hoszowski, M. Zajac eP025 Cardiac tamponade with bacterial pericarditis following open heart surgery: successful management with subxiphoid drainage and antibiotics H. Osada* (Kyoto, Japan), H. Nakajima, K. Meshii, M. Ohnaka, M. Nagao eP017 Quinolone resistance in Salmonella Newport D. Wasyl* (Pulawy, Poland), M. Zajac, A. Hoszowski eP018 Prevalence of qnr genes in 1032 invasive isolates of Escherichia coli in Croatia M. Jelic* (Zagreb, Croatia), Gužvinec, I. Butic, S. Bukovski, A. Tambic-Andraževic eP026 Perioperative infection prevention in cardiothoracic surgery T. Götting* (Freiburg, Germany), J. Rauch, M. Willhauck, W. Ebner, G. Trummer, F. Beyersdorf, M. Dettenkofer eP019 Emergence of ciprofloxacin-resistant Salmonella enterica serovar Typhi in Italy A. Garcia-Fernandez, S. Owczarek, A.M. Dionisi, I. Benedetti, I. Luzzi* (Rome, Italy) eP027 Prevalence and mechanism of fluoroquinoloneresistance in clinical isolates of Proteus mirabilis in Japan R. Nakano* (Tokyo, Japan), A. Nakano, R. Okamoto, A. Michiko, N. Nagano, M. Asahara, Y. Ono Surgical site infection in cardiothoracic surgery – a single intervention surveillance study from Lancashire Cardiac Centre comparing chlorhexidineisopropyl alcohol to iodine-IPA skin prep A. Guleri* (Blackpool, United Kingdom), R. Sharma, N. Waddington eP020 eP028 Successful sterilisation of femoral head allograft using high hydrostatic pressure M.A.J. Van de Sande, I.M. Sanders, M. Van Wijk, E.J. Kuijper* (Leiden, The Netherlands) Viewing Stations eP029 Breast-MF: identification of breast flora in patients undergoing aesthetic and oncologic breast surgery O. Streinu-Cercel, A. Streinu-Cercel, D.M. Jianu, I. Berciu, A. Blidaru, M. Filipescu, I.P. Florescu, O. Cobani, S.A. Jianu, A. Streinu-Cercel* (Bucharest, Romania) EPOSTER VIEWING: Successful reduction of surgical site infections eP021 Adherence to principles of hygiene in operating theatres: development of a monitoring system R. Fulchini* (St. Gallen, Switzerland), M. Hoffmann, B. Schoebi, K. De Martin, U. Schaefer, M. Schlegel eP022 Hospital discharge database for SSI surveillance after hip or knee arthroplasty L. Grammatico-Guillon* (Tours, France), S. Barons, C. Gaborit, E. Rusch, P. Astagneau 88 24th ECCMID / Barcelona Final Programme ePoster Viewing Saturday, 10 May 2014 - Tuesday, 13 May 2014 eP031 Quantifying the association of antibiotic consumption to carbapenem-resistance in Acinetobacter baumannii: a mathematical modelling analysis M.W. Tan* (Singapore, Singapore), D. Lye, T.M. Ng, C.B. Teng, M. Nikolaou, V.H. Tam eP032 eP033 Bloodstream infection within 48 hours of admission: the effect of healthcare-associated risk factors on antibiotic resistance – a crosssectional study J. Greig* (Plymouth, United Kingdom) MRSA/SA and C. difficile real-time PCR tests – evaluation with 2013 QCMD EQA panels G. Stefanuto, S. Chiaramello, M. Enrietto, A. Estampes* (Puteaux, France), C. Olivo eP034 Chloramphenicol use and susceptibility patterns in Israel: a national cross-sectional survey O. Nitzan* (Afula, Israel), Y. Kennes, R. Colodner, H. Edelstein, R. Raz, B. Chazan eP035 Development of within-host antibiotic-resistant Gram-negative bacteria during SDD and SOD in intensive care unit patients Y. Noteboom* (Utrecht, The Netherlands), D.S.Y. Ong, E.A. Oostdijk, M.J.M. Bonten eP036 Determining the clinical and economic impact of a formal intervention programme against carbapenem-resistant Klebsiella pneumoniae infections C.J. Clancy, O. Marroquin, K. Lynch, G. Eschenauer, R.K. Shields, B. Potoski, B. Hao, M.H. Nguyen* (Pittsburgh, United States) eP037 Safety and efficacy of outpatient parenteral antimicrobial therapy (OPAT) for spinal infections S. O’Connell* (Dublin, Ireland), C. O’Connor, D. Hare, S.J. Yeung, K. Synnott, J. Lambert, G. Sheehan, A. Poynton, M. Timlin, P. Mallon eP038 First confirmed case of spondylodiscitis and epidural abscess due to Parvimonas micra: review of Parvimonas micra infection S. Endo* (Sendai, Japan), T. Nemoto, H. Yano, H. Kanamori, T. Aoyagi, M. Hatta, Y. Gu, K. Tokuda, M. Kitagawa, M. Kaku eP039 Risk factors and surgical site infection rates related to craniotomy in a tertiary care university hospital. A prospective surveillance programme A. Soriano* (Barcelona, Spain), E. Shaw, O. Arch, A. Gabarros, D. Garcia, C. Cabellos, I. Pelegrin, C. Peña, J. Ariza, M. Pujol eP040 Cost-effectiveness analysis of appropriate duration of antibiotic prophylaxis for prevention of neurosurgical infections A. Ulu-Kilic* (Kayseri, Turkey), E. Alp Mese, F. Cevahir, H. Demiraslan, B. Tucer, A. Selcuklu, M. Doganay eP041 Infection of spinal cord stimulation devices: remove or retain? G. Béraud* (Poitiers, France), M. Roulaud, O. Monlezun, F. Guetarni, B. Bataille, P. Rigoard eP042 Risk factors for surgical site infection after microvascular reconstruction for head and neck cancer J.L. Wagner* (Detroit, United States), R.M. Kenney, T.A. Ghanem, J.A. Vazquez, S.L. Davis eP043 Significant decrease of S. aureus mediastinitis post cardiac surgery as a result of molecular nasal carrier screening and decontamination C. Plouzeau* (Poitiers, France), S. Thevenot, A.S. Cognee, M. Albouy-Llaty, A. Michaud, S. Peguilhan, P. Corbi, C. Jayle, C. Burucoa eP044 Sternal plate fixation for chest wall reconstruction post coronary artery bypass surgery appears to increase the risk of surgical site infection M. Charles* (Edmonton, Canada), L. Saxinger, S. Smith 24th ECCMID / Barcelona Final Programme ePosters Effects of an antibiotic stewardship programme on carbapenem-resistant Gram-negative epidemiology A. Stern* (Haifa, Israel), S. Haddad, M. Paul, Y. Barlavie, K. Hussein EPOSTER VIEWING: Post-surgical and implant infections: from head to knee Posters eP030 Viewing Stations Chairs, Speakers & Authors EPOSTER VIEWING: Antibiotic consumption-resistance associations Exhibition Viewing Stations 89 General Information ePoster Viewing Saturday, 10 May 2014 - Tuesday, 13 May 2014 eP045 Gram-negative rod bacteraemia following cardiovascular surgery: characteristics and clinical outcomes S. Asahata* (Shinjuku Kwadacho, Japan), Y. Ainoda, T. Fujita, Y. Hirai, A. Goto, K. Totsuka eP046 Epidemiology and risk factors for surgical site infections following thoracic surgery S. Ceken* (Ankara, Turkey), S. Simsek Yavuz, A. Sensoy, O. Imamoglu eP047 eP048 eP049 eP050 eP051 Healthcare-associated haematogenous pyogenic vertebral osteomyelitis: a severe and potentially preventable infectious disease C. Pigrau* (Barcelona, Spain), D. Rodriguez-Pardo, B. Almirante, L. Moretó, N. Fernandez-Hidalgo, N. Larrosa, M. Puig-Asensio, F. Pellisé, A. Pahissa Outcome of attempted implant retention in early and late-onset spinal implant infections M.S. Lee* (Seoul, Korea), K. Park, M. Jung, S. Moon, J.S. Son, K. Suk, J.H. Lee, J.S. Park, K.N. Rye Is there a difference in phylotype of Propionibacterium acnes strains in terms of origin: spinal material, prosthetic devices and environment? S. Delliere, P. Bemer, G.G. Aubin, C. Plouzeau, D. Tande, S. Corvec* (Nantes, France) Economic burden of surgical site infections after gynaecological operations in a middleincome country E. Alp Mese* (Kayseri, Turkey), F. Cevahir, A. Ulu-Kilic Length of time to antibiotic administration and surgical site infection in patients with open appendectomy J.A. Cortes* (Bogota, Colombia), V. Robayo, D.C. Bermudez, M. Ibañez eP052 Surgical site infection in appendectomy – is the risk different for adults and children? A. Breier* (Berlin, Germany), C. Schröder, R. Leistner, P. Gastmeier eP053 Impact of multidrug-resistant Gram-negative bacilli on organ/space infections associated to elective colorectal surgery – a prospective analysis in a university hospital in Spain E. Shaw* (Barcelona, Spain), R. Escofet, G. Cuervo, D. Garcia, O. Arch, A. Hornero, T. Vidal, C. Peña, J. Ariza, M. Pujol 90 24th ECCMID / Barcelona Final Programme eP054 Use of outpatient antimicrobial therapy (OPAT) in patients with intra-abdominal abscess after abdominal surgery A. Vivero Larraza* (Barcelona, Spain), N. Sopena Galindo, M. Piñol Pascual, M. Bonet Farell, G. Bonet papell, E. Blanco Hernandez, A. Cuxart Melich eP055 Post-arthroscopic septic arthritis of the knee analysis of the outcome after treatment in a series of cases T. Ascione* (Naples, Italy), G. Balato, P. Pagliano, R. Rotondo, G. De Stefano, M. Conte, M. Mariconda eP056 Management and clinical outcomes of Staphylococcus aureus prosthetic joint infections: a retrospective review S. Parsaei* (Saint Louis, MO, United States), N. Ganeshraj, A. Gu, P. Bodavula, J. Marschall, D. Warren, M. Lane eP057 Economic burden of prosthetic joint infections in a middle-income country E. Alp Mese* (Kayseri, Turkey), F. Cevahir, S. Ersoy, A. Guney eP058 SSI after hip or knee arthroplasty: a French cohort study using hospital discharge database, 2008-2012 L. Grammatico-Guillon* (Tours, France), S. Baron, C. Gaborit, E. Rusch, P. Astagneau eP059 Healthcare-associated infection after red blood cell transfusion: a systematic review and metaanalysis of randomised trials M.A.M. Rogers* (Ann Arbor, United States), J.M. Rohde, D.E. Dimcheff, N. Blumberg, S. Saint, K.M. Langa, L. Kuhn, A. Hickner eP060 Standards of infection control to prevent surgical site infections in Switzerland: a cross-sectional survey in 82 hospitals D. Vuichard Gysin* (Basel, Switzerland), N. Troillet, M.C. Eisenring, M. Dangel, G. Zanetti, A.F. Widmer ePoster Viewing Direct costs of hospital admission for pneumococcal and non-pneumococcal pneumonia S.M. Huijts* (Utrecht, The Netherlands), M.J.J. Mangen, D.F. Postma, C.H. Van Werkhoven, M.J.M. Bonten eP062 eP070 Factors associated with prolonged time to clinical stability in hospitalised adults with communityacquired pneumonia A.F. Simonetti, D. Viasus* (Barranquilla, Colombia), C. Garcia-Vidal, J. Carratala Hospitalisation due to respiratory syncytial virus (RSV) infection in adult patients: a retrospective cohort study C. Volling* (Toronto, Canada), K. Hassan, T. Mazzulli, K. Green, A. Al-Den, P. Hunter, R. Mangat, J. Ng, A. McGeer eP063 eP071 Beta-lactam monotherapy versus beta-lactammacrolide combination treatment in moderately severe community-acquired pneumonia: a randomised non-inferiority trial N. Garin* (Geneva, Switzerland), D. Genné, S. Carballo, C. Chuard, G. Eich, O. Hugli, P. Petignat, O. Rutschmann, S. Harbarth, A. Perrier The value of procalcitonin to determine the need for hospital admission in adults with communityacquired pneumonia A.F. Simonetti* (Barcelona, Spain), D. Viasus, C. Garcia-Vidal, J. Dorca, F. Morandeira-Rego, J. Carratala eP064 eP072 In-hospital modifications of antibacterial therapy initiated in the emergency department for community-acquired pneumonia N. Goffinet, M. Cousin, E. Montassier, C. Peron, N. Lecadet, G. Potel, E. Batard* (Nantes, France) Qualitative and quantitative analysis of the microbiota in lower respiratory tract infections reveals a high proportion of polymicrobial infections G. Platt* (London, United Kingdom), S. Schwenk, Y. Personne, K. Thomas, V. Gant, V.I. Enne, A.I. Zumla eP065 eP073 Community-acquired pneumonia caused by Staphylococcus aureus in France: interim results of a prospective cohort study M. Saadatian-Elahi* (Lyon, France), A. Tristan, Y. Gillet, M. Bes, C. Bouchiat, O. Dumitrescu, C. Picard, L. Argaud, F. Vandenesch Microbiological investigation of patients with community-acquired pneumonia using quantitative multiplex real-time bacterial PCR C.D. Russell* (Edinburgh, United Kingdom), N.J. Gadsby, H. Mark, D. Guerendiain, A. Conway Morris, I.F. Laurenson, A.T. Hill, K.E. Templeton Predictors of bacteraemia in patients hospitalised with suspected community-acquired pneumonia: a cohort study C.H. Van Werkhoven* (Utrecht, The Netherlands), S.M. Huijts, D.F. Postma, J.J. Oosterheert, M.J.M. Bonten eP066 Antibiotic treatment patterns and outcomes among patients hospitalised in ICU with community-acquired bacterial pneumonia: a US cohort study S. Eapen* (Boston, United States), E. Tuttle, C. Llop, M. Barrett eP067 Impact of initial antibiotic failure on duration of hospitalisation (DOH) for community-acquired pneumonia (CAP): results of a randomised clinical trial of ceftaroline fosamil versus ceftriaxone N. Zhong, T. Sun, G. D’Souza, S.H. Lee, H.L. Nguyen, C.-H. Chiang, D. Wilson, F. Sun, D. Melnick* (Wilmington, United States) 24th ECCMID / Barcelona Final Programme 91 General Information eP061 Posters eP069 EPOSTER VIEWING: Community-acquired pneumonia Chairs, Speakers & Authors Mortality and hospital length of stay (HLOS) among patients with community-acquired pneumonia (CAP): a propensity score-matched analysis of ceftaroline fosamil (CPT-F)-treated vs ceftriaxone-treated patients Y. Golan* (Boston, MA, United States), R. Ruthazer, M. Ding, Q. Zhao, X. Huang Viewing Stations Exhibition eP068 ePosters Saturday, 10 May 2014 - Tuesday, 13 May 2014 ePoster Viewing Saturday, 10 May 2014 - Tuesday, 13 May 2014 Viewing Stations eP081 Reduction in the number of patients with neuroborreliosis, following a significant reduction in roe deer abundance on the island of Fuen, Denmark N.S. Andersen* (Odense, Denmark), P.M. Jensen, S. Skarphédinsson, C.R. Olesen, T.G. Jensen, H.J. Kolmos eP082 A 5-year observational study of the epidemiology of Lyme borreliosis in Scotland S. Mavin* (Inverness, United Kingdom), R. Evans eP083 Identification of complex species of Borrelia burgdorferi using MALDI-TOF mass spectrometry, it’s possible! S.J. De Martino* (Strasbourg, France), F. Schramm, P. Riegel, L. Zilliox, B. Jaulhac eP084 Presence of Lyme disease agents in the Portuguese ixodofauna: development of realtime PCR assays for the identification of Borrelia burgdorferi genospecies M. Nunes* (Lisbon, Portugal), N. Lopes, C. Maia, T. Carreira, J. Inácio, M.L. Vieira eP085 Usefulness of quantitative IgG assays Borrelia VlsE liaison and the new VIDAS® Lyme for serological follow-up of patients with Lyme borreliosis O. Péter* (Sion, Switzerland), R. Vonlanthen, A. Bonnet-Pierroz, A. Schaller, C. Béguelin, D. Genné, R. Lienhard EPOSTER VIEWING: Lyme borreliosis eP074 Intrathecal Th17 response in Lyme neuroborreliosis and the relation to clinical disease course P. Gyllemark, A. Matussek, P. Forsberg, J. Ernerudh, A.J. Henningsson* (Jönköping, Sweden) eP075 CXCL13 concentrations in cerebrospinal fluid of Lyme neuroborreliosis and other neuroinflammatory patients J. Hytönen* (Turku, Finland), E. Kortela, J. Salo, M. Waris, J. Oksi eP076 Comparison of a cell-based SpiroFind assay with classical serology for the diagnosis of acute Lyme borreliosis M. Lupse* (Cluj, Romania), M. Oosting, M. Flonta, O. Daraban, J.W.M. Van der Meer, M.G. Netea, L.A.B. Joosten, B.J. Kullberg eP077 Epidemiology and costs of Lyme borreliosis hospital care in Germany: lessons from a health care utilisation database analysis B. Lohr* (Frankfurt, Germany), I. Müller, O. Schöffski, K.-P. Hunfeld eP078 Erythema migrans and re-infection with Borrelia burgdorferi species – analysis of patients with early form of Lyme disease in north-eastern Poland A. Moniuszko* (Bialystok, Poland), S. Pancewicz, K. Guziejko, J. Dunaj, R. Swierzbinska, M. Kondrusik, S. Grygorczuk, P. Czupryna, P. Aleksiejczuk, J. Zajkowska Viewing Stations EPOSTER VIEWING: Molecular diagnosis of bacterial gastrointestinal infections eP079 Clinical and microbiological characteristics of Slovenian patients with Bannwarth’s syndrome K. Ogrinc* (Domzale, Slovenia), S. Lotric-Furlan, D. Stupica, V. Maraspin, P. Bogovic, T. Rojko, T. Cerar Kisek, E. Ruzic-Sabljic, F. Strle eP086 Evaluation of a multiplex PCR for the detection of bacterial and parasitic pathogens in clinical stool samples compared with conventional methods I. Cooper* (Brisbane, Australia), R. Vohra, P. O’loughlin, J. Sergent, T. Bruce eP080 Course and outcome of solitary erythema migrans in patients treated for breast cancer V. Maraspin* (Ljubljana, Slovenia), J. Cimperman, E. Ruzic-Sabljic, F. Strle eP087 Multiplex PCRs for the diagnosis of gastrointestinal pathogens are unreliable for the detection of Salmonella enterica L.R. Macfarlane-Smith* (Leeds, United Kingdom), K.A. Davies, H.M. Ashwin, L.J. Pankhurst, L.W. Anson, A.S. Walker, D.W. Crook, M.H. Wilcox 92 24th ECCMID / Barcelona Final Programme ePoster Viewing Saturday, 10 May 2014 - Tuesday, 13 May 2014 eP093 eP094 eP095 A diagnostic screening algorithm to optimise detection of Shigella spp. and entero-invasive Escherichia coli R.F. De Boer* (Groningen, The Netherlands), A. Ott, W. De Boer, M.C. Scholts, K. Van Huisstede, A.M.D. Kooistra-Smid Prevalence and molecular characterisation of shiga-toxin-producing E. coli of patients in the northern and western region of The Netherlands M. Ferdous* (Groningen, The Netherlands), A.M.D. Kooistra-Smid, R.F. De Boer, H. Fijan, P. Van Barneveld, A.W. Friedrich, J.W.A. Rossen Case-control study gastroenteritis: value of molecular diagnostics A.G.M. Zanden van der* (Hengelo, The Netherlands), T.A. Schuurs, J.F.L. Weel, G.J.H.M. Ruijs, W.A. Reijden van der, L. Mulder, L.E.S. Bruijnesteijn van Coppenraet External quality assessment of laboratories using molecular diagnostic tests for Clostridium difficile E. Mcculloch* (Glasgow, United Kingdom), P.S. Wallace, J. Coia, C. Williams, W.G. Mackay eP096 Hospital characteristics associated with higher Staphylococcus aureus bacteraemia mortality in Veterans Affairs Healthcare System: a retrospective cohort study M. Goto* (Iowa City, IA, United States), M.L. Schweizer, E.N. Perencevich, M.E. Ohl eP097 Influence of methicillin-resistance on mortality in a large cohort of patients with Staphylococcus aureus bloodstream infection C. Feijoó* (Barcelona, Spain), O. Gasch, M.L. Machado, N. Muñoz, M. Espasa, M. Navarro, L. Falgueras, B. Font, D. Fontanals, F. Segura eP098 Predictors of persistent S. aureus bacteraemia and impact on related mortality L. Morata* (Barcelona, Spain), I. Alejo, I. Fernández, N. Cobos-Trigueros, C. De la Calle, M. Almela, F. Marco, J.A. Martínez, A. Soriano, J. Mensa eP099 Clinical analysis of prognostic factors in methicillin-resistant Staphylococcus aureus bloodstream infection: association with 30-day mortality M. Maeda* (Tokyo, Japan), H. Shoji, K. Fukuchi, T. Shirakura, T. Takuma, K. Tanaka, K. Ishino, Y. Niki eP100 Factors associated with case-fatality in Staphylococcus aureus bacteraemia, a large observational study P. Braquet* (Montpellier, France), L. Minary, C. Cornu, L. Piroth, E. Curlier, M. Revest, C. Lechiche, V. Le Moing eP101 Lack of correlation between clinical parameters of sepsis and molecular strain typing in Staphylococcus aureus J. Zhang, K. Wu, J. McClure, K. Zhang, J. Conly* (Calgary, Canada) eP102 Characteristics and prognosis of patients with staphylococcal prosthetic vascular graft infection (PVGI): a prospective cohort of 92 patients A. Pasquet* (Tourcoing, France), M. Valette, L. Legout, P. Choisy, P. D’elia, B. Saraz-Bournet, O. Leroy, E. Senneville 24th ECCMID / Barcelona Final Programme ePosters eP092 Molecular detection of Shigella spp. impacts on apparent epidemiology and reference laboratory workload N. De Lappe, J. O Connor, D. Morris* (Galway, Ireland) EPOSTER VIEWING: Sepsis, bloodstream and graft infections: Staphylococcus aureus and others Posters eP091 Detection of verocytotoxin-producing E. coli (VTEC) needs a change in culture G.L. Vanstone* (London, United Kingdom), C. Jenkins, R. Smith Viewing Stations Chairs, Speakers & Authors eP090 Rapid microbial diagnosis of acute gastroenteritis: comparison of three multiplexed molecular tests on 194 paediatric stool samples. Are culture methods obsolete? A. Beucher, N. Vernet, G. Maccio, P.O. Verhoeven, J.M. Roque, A. Epercieux, Y. Mekki, F. Vandenesch, A.M. Freydiere, O. Dauwalder* (Bron, France) Exhibition eP089 Evaluation of the fully automated real-time BD MAX™ enteric bacterial panel assay M.D. Perry* (Cardiff, United Kingdom) 93 General Information eP088 ePoster Viewing Saturday, 10 May 2014 - Tuesday, 13 May 2014 eP103 Risk factors, prognostic factors and outcome in patients with bloodstream infection caused by Klebsiella pneumoniae versus Escherichia coli M. Vading* (Stockholm, Sweden), P. Nauclér, M. Kalin, C.G. Giske eP104 Outcome in patients with community-onset bacteraemia and septic shock: pathogen species and infection sites are associated with mortality C. Hernandez* (Barcelona, Spain), C. Fehér, N. Cobos, L. Morata, C. DeLaCalle, M. Almela, A. DelRio, J. Mensa, A. Soriano, J.A. Martínez eP105 Are incidence and epidemiology of anaerobic bloodstream infections really changing? A ten-year retrospective study A. Vena* (Madrid, Spain), M. Rodriguez-Creixéms, C. Sanchez, L. Alcalà, P. Muñoz, E. Bouza Viewing Stations EPOSTER VIEWING: Multifaceted approaches to reduce MDR Gram-negative infections eP106 Are contact precautions for extended-spectrum beta-lacatase-producing Gram-negative rods warranted in areas of high endemicity? S. Mahmood* (Karachi, Pakistan), R. Khowaja, S. Musani, N. Nosheen, R. Roshan eP107 Stenotrophomonas maltophilia infections and controls in intensive care unit K. Suer, M. Guvenir* (Lefkosa, Cyprus), N. Cakir eP108 First outbreak of carbapenemase-producing Klebsiella pneumoniae strain (ST512) in a Finnish long-term acute care hospital, June 2013 M. Kanerva* (Helsinki, Finland), K. Skogberg, A. Pahkamäki, K. Ryynänen, J. Jalava, E. Tarkka, O. Lyytikäinen eP109 First documented outbreak of KPC-2 producing K. pneumoniae in Switzerland: infection control measures and clinical management E. Lemmenmeier* (St.Gallen, Switzerland), P. Kohler, T. Bruderer, D. Goldenberger, J.R. Kleger, M. Schlegel eP110 First outbreak of OXA-232-producing Klebsiella pneumoniae in a Korean secondary care hospital J. Chae* (Seoul, Korea), W. Choe, M. Kim eP111 Evaluation of knowledge of hairdressers on blood-borne diseases S. Ozcimen* (Konya, Turkey), L.S. Demir, N. Demir 94 24th ECCMID / Barcelona Final Programme eP112 Management and investigation of a large outbreak of Enterobacteriaceae-producing OXA-48 carbapenemase in a French university hospital B. Semin-Pelletier, C. Bourigault, M.E. Juvin, S. Pineau, D. Boutoille, C. Agard, M. Hourmant, S. Corvec, J. Caillon, D. Lepelletier* (Nantes, France) eP113 Nosocomial spread of metallo-beta-lactamase producing Pseudomonas aeruginosa in a university hospital with possible link to contaminated sink drains – an outbreak report A. Stjarne Aspelund* (Lund, Sweden), B. Olsson Liljequist, E. Melander eP114 Metallo-beta-lactamase producing Pseudomonas aeruginosa outbreak in the children’s ICU B. Kotnik Kevorkijan* (Maribor, Slovenia), G. Novak, A. Golle, S. Lorencic Robnik, S. Janežic, M. Rupnik eP115 Campylobacter concisus pseudo-outbreak caused by improved culture conditions C. Casanova* (Berne, Switzerland), A. Schweiger, N. Von Steiger, S. Droz, J. Marschall eP116 Nosocomial outbreak of Acinetobacter baumannii producing a plasmid-encoded OXA-23 betalactamase associated with the insertion sequence ISAba4 in Spain I. Guerrero-Lozano, F. Fernandez-Cuenca, F. Galan-Sanchez, P. Egea, M.A. Rodríguez-Iglesias* (Cadiz, Spain), A. Pascual eP117 Evolution of MIC values of colistin in MDR-Acinetobacter baumannii after the implementation of a multicomponent intervention programme to control MDRAB University Hospital Virgen del Rocío V. Gonzalez Galan* (Seville, Spain), J.A. Lepe, M.J. Artacho, R. Valencia, A. Cazalla, R. Alvarez, J.M. Cisneros, J. Aznar eP118 First description of a long-term, low frequency outbreak of a GIM-1-producing Enterobacter cloacae ST-89 in a tertiary care hospital in Germany A.F. Wendel* (Düsseldorf, Germany), S. Kolbe-Busch, S. Ressina, R. Deenen, K. Köhrer, S. Wohlfromm, K. Pfeffer, C.R. MacKenzie eP119 Lessons from an outbreak of a KPC-2 producing Klebsiella pneumoniae strain A. Rodloff* (Leipzig, Germany), N. Lippmann, S. Faucheux, C. Lübbert, T. Kaiser, U. Kaisers ePoster Viewing Saturday, 10 May 2014 - Tuesday, 13 May 2014 eP127 Value of PET/CT for the diagnosis and management of infective endocarditis N. Fernández-Hidalgo* (Barcelona, Spain), G. Oristrell, M.N. Pizzi, A. Roque, M.T. Gonzàlez-Alujas, M. Galiñanes, S. Aguadé, P. Tornos, B. Almirante eP128 Mortality determinants in 4340 infective endocarditis cases in France S. Sunder* (Tours, France), L. Guillon, C. Gaborit, L. Pericart, E. Rusch, L. Fauchier, S. Baron, L. Bernard EPOSTER VIEWING: Infective endocarditis and cardiovascular device infections Characteristics of infective endocarditis in French West Indies: a 13-year observational study E. Fernandes* (Pointe A Pitre, Guadeloupe), C. Olive, J. Inamo, R. Theodose, F. Roques, D. Courcier, A. Cabie, B. Hoen, P. Hochedez eP122 Bartonella infective endocarditis: a 20-year experience in a Tunisian tertiary care centre S. Ben Kahla, L. Abid, M. Koubaa, A. Znazen, D. Abid, A. Hammami, M. Ben Jemaa* (Sfax, Tunisia), S. Kammoun eP123 Length of treatment and outcome of enterococcal endocarditis treated with ampicillin plus ceftriaxone. A comparison with standard ampicillin plus gentamicin regimen J. Pericas* (Barcelona, Spain), C. Cervera, A. Moreno, C. Garcia-de-la-Mària, C. Falces, M. Almela, Y. Armero, J.M. Gatell, C.A. Mestres, J.M. Miro eP124 eP125 eP126 Viewing Stations EPOSTER VIEWING: Vaccine development Prokaryotic chimera protein consisting of multiple M2e of influenza A virus and Leishmania major HSP70 induced specific immune responses in mice F. Fotouhi* (Tehran, Iran), N. Taheri, H. Soleimanjahi, B. Farahmand, M.T. Kheiri, A. Torabi, Z. Kianmehr eP130 Chimeric influenza virosome M. Tavassoti Kheiri* (Tehran, Iran), A. Abdoli, H. Soleimanjahi, A. Jamali eP131 Characteristics and outcome of polymicrobial infections of cardiovascular implantable electronic devices S. Carbonara* (Bari, Italy), G. Luzzi, C. Fabrizio, A. Mosca, Z. Palamà, R. Trotta, F. Napoli, S. Favale, G. Miragliotta, G. Angarano The cost-effectiveness of vaccination against seasonal influenza in England M. Baguelin* (London, United Kingdom), A. Camacho, S. Flasche, J.W. Edmunds eP132 Cardiovascular implantable electronic device infections: correlation between microbiology and clinical presentation E. Carrara* (Pavia, Italy), E. Seminari, L. Scudeller, R. Rordorf, A. Vicentini, M. Brandolini, P. Marone, L. Minoli, A. Di Matteo A phase II study of the safety and immunogenicity of different formulations of a candidate Clostridium difficile toxoid vaccine: dose and formulation selection for phase III G. De Bruyn* (Swiftwater, United States), G. Foglia, J. Saleh, D. Workman, R. Pollak, R. Gesser eP133 A phase II study of the safety and immunogenicity of different vaccination schedules of a candidate Clostridium difficile toxoid vaccine: vaccination schedule selection for phase II G. De Bruyn* (Swiftwater, United States), G. Foglia, J. Saleh, D. Workman, R. Pollak, R. Gesser Evaluation of ventricular assist device-related infections C. Buke* (Izmir, Turkey), T. Yagdi, C. Engin, F. Cilli Hall, A.L.P. Aslan, M. Ozbaran 24th ECCMID / Barcelona Final Programme ePosters eP129 95 Posters eP121 Prevalence and risk factors for infective endocarditis in patients with Staphylococcus aureus bacteraemia B. Varatharaj Palraj* (La Crosse, United States), L.M. Baddour, J.M. Steckelberg, W.R. Walter, M.R. Sohail Chairs, Speakers & Authors eP120 Exhibition Viewing Stations General Information ePoster Viewing Saturday, 10 May 2014 - Tuesday, 13 May 2014 eP134 eP135 eP136 eP137 eP138 Safety, tolerability, and immunogenicity of a novel 4-antigen Staphylococcus aureus vaccine (sa4ag) in healthy adults: results of a randomized, placebo-controlled first-in-human phase 1/2 study R. Frenck* (Cincinnati, United States), C. Buddy Creech, E. Sheldon, D.J. Seiden, M. Kankam, J. Baber, E. Zito, R. Hubler, J. Eiden, J.M. Severs, S. Sebastian, J. Nanra, K.U. Jansen, A.S. Anderson, D. Girgenti eP141 Inter-lineage cross-protection induced by a West Nile virus lineage 1 recombinant domain III vaccine W. Widagdo (Rotterdam, The Netherlands), S. Lim, B. Martina eP142 Reducing the risk of tick-borne diseases – identification of vaccine candidates against Ixodes ricinus W. Jochum* (Luxembourg, Luxembourg), A.L. Reye, O. Hunewald, C.P. Muller Development and evaluation of Staphylococcus epidermidis DNA, mRNA and protein vaccines L. Yan* (Seattle, United States), J. Bryers eP143 Analysis of the proteome of a modified vaccinia virus Ankara-based vaccine provides insight into the effects of transgenic modification on virus physiology A.S. Okoli* (Tromsoe, Norway), M.I. Okeke, C. Tummler, U. Moens, O. Nilssen, M. Tryland, J. Ansgar-Bruun, T. Bøhn, T. Traavik Use of a Staphylococcus aureus small colony variant as an attenuated live vaccine for the prevention of intramammary infections J. Côté-Gravel* (Sherbrooke, Canada), E. Brouillette, N. Obradovic, M. Allard, B. Talbot, C. Ster, F. Malouin eP144 Knowledge and risk perception of measles and factors associated with vaccination decisions in subjects consulting university affiliated public hospitals after measles infection: a retrospective epidemiological study M. Saadatian-Elahi* (Lyon, France), A. Toure, D. Floret, B. Lina, J.S. Casalegno, P. Vanhems eP145 FMD vaccine (Ronavac®) potency, stability, safety and efficacy test P. Zare, J. Shalmashi, O. Fakhri* (Tabriz, Iran), F. Ghaderi, Y. Farshi, S. Shadi eP146 Advancing the development of an effective Staphylococcus aureus vaccine by targeting multiple bacterial virulence factors A.S. Anderson, I.L. Scully, P.A. Liberator, D. Cooper* (Pearl River, United States), J. Baber, D.Q. Girgenti, E. Zito, J. Eiden, W. Gruber, E. Emini, K.U. Jansen eP147 Development of an oral vaccine against candidiasis using molecular display technology S. Shibasaki* (Kobe, Japan), M. Ueda T-helper cell cytokine pattern induced by synthetic manno-and gluco-oligosaccharide conjugates E. Paulovicova, R. Pilisiova* (Bratislava, Slovakia), L. Paulovicova, D.V. Yashunsky, A.A. Karelin, Y.E. Tsvetkov, N.E. Nifantiev Immunisation with enolase of Trypanosoma cruzi confers protective immunity against acute phase of Chagas disease in mice A. Carabarin-Lima, G. Cortés-Cortés* (Puebla, Mexico), M.C. González-Vázquez, O. Rodríguez-Morales, P.A. Reyes, M. Arce-Fonseca, J.L. Rosales-Encina eP139 Vaccination with a lipopolysaccharide-deficient inactivated whole cell vaccine provides protection against experimental Acinetobacter baumannii infection M. García Quintanilla* (Seville, Spain), J. Pachón Díaz, M.J. McConnell eP140 Development of a novel six-valent recombinant protein vaccine against toxoplasmosis using antigens discovered by high-throughput protein microarray analysis of patient and infected murine model sera M. Doskaya* (Izmir, Turkey), E. Atalay, L. Liang, A. Caner, H. Can, S. Gulce Iz, D.H. Davies, A. Degirmenci Doskaya, P.L. Felgner, Y. Guruz 96 24th ECCMID / Barcelona Final Programme ePoster Viewing Saturday, 10 May 2014 - Tuesday, 13 May 2014 Retrospective database analysis of the impact of pneumococcal conjugate vaccines on otitis media and pneumonia among children in Germany A. Busse, M. Laurenz, R. Sprenger, C. Von Eiff* (Berlin, Germany) eP157 A Streptococcus pneumoniae serotype 19F wzy variant in Venezuela and pneumococcal vaccine cross-protection M.C. Sisco* (Caracas, Venezuela), I.A. Rivera-Olivero, E. Simonetti, C. De Jong, J. Hinds, P.W. Hermans, J.H. De Waard eP158 Pherotype diversity is not affected by conjugate vaccine-induced serotype changes J. Diamantino-Miranda, S.I. Aguiar, J. Melo-Cristino, M. Ramirez* (Lisbon, Portugal) eP159 Feasibility of a single priming dose of the meningococcal group C conjugate vaccine NeisVac-C in infants E.M. Poellabauer, B.G. Pavlova, S. Fritsch, J. Singer, C. Neubauer, R. Petermann* (Vienna, Austria), J. Doralt, B. Valenta-Singer, G. Aichinger eP160 Plasmablasts and antibody response to Haemophilus influenzae type B vaccine in patients with chronic lymphocytic leukemia E. Grywalska* (Lublin, Poland), A. Surdacka, I. Korona-Glowniak, A. Malm, J. Rolinski Recombinant vaccine for prevention of Streptococcus pneumoniae infection A. Suvorov* (St. Petersburg, Russia), G. Leontieva, A. Orlov, N. Kramskaya, I. Koroleva, I.L.I.A. Dukhovlinov eP149 Distribution of serotypes causing invasive pneumococcal disease in adults in 2010-2013 in Spain (Odin study group) A. Fenoll* (Madrid, Spain), E. Cercenado, C. Ardanuy, F. Marco, A. Fleites, J.L. Lopez-Hontangas, M.C. Zuñiga, B. Palop, J. Liñares, I. Cifuentes eP150 Per-serotype clinical presentations of invasive pneumococcal disease in adults in Spain (2010-2013). The Odin study group A. Torres* (Madrid, Spain), A. Burillo, R. Pallares, L. Molinos, M. Salavert, D. Sousa, J.L. De la Cruz, I. Alfageme, A. Fenoll, I. Cifuentes eP151 Serotype distribution and burden of pneumococcal disease in adults in Germany – reaching the limit of herd protection? M. Van der Linden* (Aachen, Germany), M. Imöhl eP152 Impact of pneumococcal conjugate vaccine on invasive pneumococcal diseases in children less than 5 years of age in Morocco I. Diawara* (Casablanca, Morocco), K. Zerouali, K. Katfy, H. Belabbes, N. Elmdaghri eP153 In vitro fitness analysis of pneumococcal strains before and after introduction of the conjugate vaccine (PCV7) – what are the most accurate parameters? J.P. Fobiwe* (Jena, Germany), O. Makarewicz, U. Schumacher, M. Lucas, M. Van der Linden, M. Pletz eP154 Invasive pneumococcal disease in children and adolescents: incidence of infection and serotype coverage of conjugate vaccines in Portugal S.I. Aguiar, M.J. Brito, A. Horácio, J.P. Lopes, M. Ramirez* (Lisbon, Portugal), J. Melo-Cristino eP155 Distribution of serotypes causing invasive pneumococcal disease in adults in Galicia (Spain) during 2011 and 2012: associated risk factors, mortality and antibiotic susceptibility S. Mendez Lage, J.A. Agulla Budiño* (Ferrol, Spain), I. Losada Castillo, A. Malvar Pintos, X. Hervada Vidal, P.G.G. Pneumococcal Group from Galicia Viewing Stations EPOSTER VIEWING: Molecular typing of staphylococci eP161 One-year epidemiological and molecular analysis of community- and hospital-associated methicillin-resistant Staphylococcus aureus in a tertiary hospital in Japan using phage openreading frame typing S. Inomata* (Sendai-City, Japan), K. Tokuda, H. Yano, C. Ishizawa, S. Endo, H. Kanamori, T. Aoyagi, M. Hatta, Y. Gu, M. Kaku eP163 Relationship between the evolution of methicillin-resistant Staphylococcus aureus and the internal structure of variable-number tandem repeat regions Y. Skryabin* (Obolensk, Russia), I. Abaev, I. Dyatlov, D.M. Donovan 24th ECCMID / Barcelona Final Programme 97 Posters eP148 Chairs, Speakers & Authors EPOSTER VIEWING: Vaccines for pneumococci, Haemophilus and meningococci ePosters eP156 Exhibition Viewing Stations General Information ePoster Viewing Saturday, 10 May 2014 - Tuesday, 13 May 2014 eP164 eP165 High-resolution melting analysis for methicillinresistant Staphylococcus aureus spa typing W. Mazi* (Stockholm, Sweden), V. Sangal, A. Saeed, G. Sandstorm, J. Yu Molecular characterisation of methicillinresistant Staphylococcus aureus surveillance isolates in South Africa A. Singh-Moodley* (Sandringham, South Africa), O. Perovic Viewing Stations EPOSTER VIEWING: Antibacterial drug activity and interactions in Gram-positive organisms eP170 Vancomycin MIC creep: a fact or an artifact? M. Souli* (Athens, Greece), H. Giamarellou On behalf of The Hellenic Study Group on Staphylococcal Infections eP166 Population dynamics of Staphylococcus aureus recovered from the airways of cystic fibrosis patients during a longitudinal prospective observational multi-centre study N. Braun, T. Janssen, C. Vogel, S. Deiwick, K. Becker, G. Peters, B. Kahl* (Münster, Germany) eP171 Current analysis of oritavancin potency when tested against vancomycin-resistant/susceptible enterococcal clinical isolates recovered from European medical centres (2009-2013) R.E. Mendes* (North Liberty, United States), D.J. Farrell, J.M. Streit, R.N. Jones eP167 Is EMBP a marker of invasiveness of Staphylococcus epidermidis (SE) strains in prosthetic joint infection? M. Titecat* (Lille, France), C. Loiez, B. Grandbastien, E. Senneville, H. Migaud, R. Courcol, F. Wallet eP172 eP168 Molecular typing of toxic shock syndrome toxin-1 and enterotoxin A-producing methicillin-sensitive Staphylococcus aureus isolates from a neonatal intensive care unit F. Layer* (Wernigerode, Germany), A. Sanchini, B. Strommenger, C. Bührer, K. Schenkel, J. Bätzing-Feigenbaum, U. Nübel, P. Gastmeier, T. Eckmanns, G. Werner Activity of oritavancin and comparator agents against multidrug-resistant staphylococcal and streptococcal isolates responsible for documented infections in European hospitals (2011-2013) R.E. Mendes* (North Liberty, United States), D.J. Farrell, R.K. Flamm, H.S. Sader, R.N. Jones eP173 Longitudinal study of the activity of oritavancin (ORI) against Staphylococcus aureus (SA) from Europe (EU) between 2011 and 2013 D.F. Sahm* (Saint Laurent, QC, United States), D.C. Draghi, G. Moeck, F.F. Arhin eP174 Oritavancin does not antagonise the activity of common antibacterial agents for Gram-positive and Gram-negative infections A. Belley* (Saint Laurent, QC, United States), F.F. Arhin, G. Moeck eP175 Susceptibility of clinical Staphylococcus and Enterococcus isolates to glycopeptides, linezolid and daptomycin in oncohaematological patients in northwestern Greece, during a two-year period E. Priavali, C. Gartzonika, P. Karagianni, E. Nita, E. Gesouli, S. Levidiotou* (Ioannina, Greece) eP176 Mutant prevention concentration (MPC) values of tedizolid (TDZ) against clinical strains of methicillin-resistant Staphylococcus aureus (MRSA) shows a low propensity for resistance selection A. Alsaeed, S. Shebelski, J. Blondeau* (Saskatchewan, Canada) eP169 98 Clonal relationship of environmental Staphylococcus epidermidis in hospital and non-hospital environments M. Heydorn, L. Radtke, J. Knobloch* (Lübeck, Germany) 24th ECCMID / Barcelona Final Programme ePoster Viewing eP179 eP180 eP181 eP182 In vitro activity of ceftaroline against Staphylococcus aureus using concentrations achieved in humans determined by time-kill methodology M. Kresken* (Rheinbach, Germany), B. Körber-Irrgang Allosteric site missense mutations in PBP2a affecting ceftaroline susceptibility detected in epidemic HA-MRSA clonotypes ST228 (south German) and ST247 (Iberian) in western Switzerland W.L. Kelley, A. Jousselin, C. Barras, E. Lelong, A. Renzoni* (Geneva, Switzerland) Comparative in vitro efficacy of ceftaroline and other anti-staphylococcal antibiotics against a nationwide collection of nosocomial Staphylococcus aureus clinical isolates from Greece M. Souli* (Athens, Greece), H. Giamarellou On behalf of The Hellenic Study Group on Staphylococcal Infections In vitro antimicrobial activity of ceftaroline against S. aureus strains isolated in Spain A. Tenorio-Abreu* (Hueva, Spain), J. Gil Tomás, E. Rodríguez-Molins, R. Ortiz de Lejarazu Leonardo, M. Borrás Máñez, J. Colomina Rodríguez, J.M. Saavedra Martín, A. Márquez Sanabria, A. Domínguez Castaño, M. De La Iglesia Salgado eP186 In vitro activities of telavancin, vancomycin and linezolid against Gram-positive organisms isolated from cancer patients K. Rolston* (Houston, TX, United States), W. Wang, L. Nesher, E. Coyle, S. Shelburne, R. Prince eP187 Antimicrobial activity of ceftobiprole tested against staphylococci and streptococci from European countries and Israel (2013) R.K. Flamm* (North Liberty, IA, United States), D.J. Farrell, J.M. Streit, H.S. Sader, R.N. Jones eP188 Ceftobiprole activity tested against bacterial isolates from hospitalised patients with pneumonia in European hospitals and Israel (2013) R.K. Flamm* (North Liberty, IA, United States), D.J. Farrell, J.M. Streit, H.S. Sader, R.N. Jones eP189 In vitro and in vivo susceptibility of Streptococcus pyogenes to trimethoprim-sulphamethoxazole in northern Australia A.C. Bowen* (Casuarina, Australia), S.Y.C. Tong, M.I. McDonald, J.R. Carapetis eP190 Comparison of solithromycin MIC against respiratory streptococci determined by EUCAST and CLSI broth microdilution methodology I. Morrissey* (Epalinges, Switzerland), P. Fernandes, B. Lemos, S. Hawser eP191 Antimicrobial activity of solithromycin tested against serotyped macrolide-resistant Streptococcus pneumoniae collected from medical centres across the USA (2012) D.J. Farrell* (North Liberty, IA, United States), R.E. Mendes, R.N. Jones eP183 In vitro activity of ceftaroline against EP15T mecC-positive methicillin-resistant Staphylococcus aureus from humans and livestock E. Cercenado* (Madrid, Spain), F. García-Garrote, M. Marín, A. Vindel, A. Méndez, E. Bouza eP192 Comparison of commercial methods with broth microdilution for determining beta-lactam susceptibilities of Streptococcus pneumoniae isolates M. Charles* (Edmonton, Canada), B. Berenger, L. Turnbull, R. Rennie, J. Fuller eP184 The use of natural alkaloids and flavonoids in combination with antibiotics to prevent and control Staphylococcus aureus biofilms A.C. Abreu* (Porto, Portugal), I. Gomes, J. Malheiro, M. Simões eP193 Activity of ceftaroline against clinically relevant strains of penicillin non-susceptible S. pneumoniae I. Burckhardt* (Heidelberg, Germany), J. Panitz, P. Jaehn, S. Zimmermann 24th ECCMID / Barcelona Final Programme Posters Pharmacodynamic profile of commonly utilised parenteral therapies against methicillinsusceptible/resistant Staphylococcus aureus from US hospitals S.T. Housman, C.A. Sutherland, D.P. Nicolau* (Hartford, United States) Activity of the peptide deformylase inhibitor GSK1322322 against intracellular forms of susceptible and resistant S. aureus: comparison with azithromycin, clindamycin, linezolid, vancomycin, daptomycin, and moxifloxacin F. Peyrusson, P.M. Tulkens* (Brussels, Belgium), F. Van Bambeke Chairs, Speakers & Authors eP178 eP185 Exhibition Beta-lactam combinations with daptomycin provide synergy against methicillin-resistant Staphylococcus aureus and vancomycinresistant enterococci J. Smith* (Royal Oak, United States), K. Barber, M. Rybak 99 General Information eP177 ePosters Saturday, 10 May 2014 - Tuesday, 13 May 2014 ePoster Viewing Saturday, 10 May 2014 - Tuesday, 13 May 2014 eP194 A novel approach using biofilm-time-kill-curves to assess bactericidal activity of daptomycin combinations against biofilm-producing Enterococcus faecium (EFM) and Enterococcus faecalis (EFC) K. Barber* (Royal Oak, United States), J. Smith, A. Raut, M. Rybak eP201 Telavancin activity against uncommonly isolated Gram-positive pathogens responsible for documented infections in hospitals worldwide (2011-2013) when using a revised susceptibility testing method R.E. Mendes* (North Liberty, United States), H.S. Sader, R.K. Flamm, R.N. Jones eP195 In vitro activity of cloxacilin against haemolytic streptococci, pneumococci and Enterococcus faecalis K. Ghathian* (Hvidovre, Denmark), N. Frimodt-Møller, C. Andersen eP202 Epidemiology and antimicrobial susceptibility of bacteria isolated from adults with complicated skin and soft tissue infections in Belgium: results from a premium ceftaroline study J. Verhaegen, K. Magerman, H. De Beenhouwer, G. Claeys* (Ghent, Belgium), D. Pierard, M. Ieven, A. Vankeirsbilck eP203 Effect of inoculum size, incubation temperature, pH, atmosphere, serum, and combination/ synergy testing on the in vitro antibacterial activity of AZD0914 M.D. Huband, R.A. Giacobbe, S. Patey* (Waltham, United States) eP204 Cycloserine as an alternative urinary tract infection therapy; susceptibilities of 500 urinary pathogens to standard and alternative therapy antimicrobials R. Kugathasan* (London, United Kingdom), M. Wootton, R. Howe eP205 Phage sensitivity of multiresistant strains of microorganisms A. Melkumyan* (Moscow, Russia), A. Mitichkin, B. Berezhanskiy, O. Varnavin, A. Alekseev Viewing Stations EPOSTER VIEWING: Antibacterial activity and drug interactions – miscellaneous organisms and agents eP196 eP197 eP198 Determination of minimum inhibitory extracellular concentrations (MIECs) against intracellular Francisella tularensis subsp. Holarctica using a dye uptake assay V. Sutera* (Grenoble, France), Y. Caspar, S. Boisset, M. Maurin In vitro susceptibility of Chlamydia trachomatis strains isolated from Croatian patients S. Ljubin-Sternak, T. Mestrovic* (Samobor, Croatia), T. Vilibic-Cavlek, M. Sviben, G. Mlinaric-Galinovic, A. Markotic, V. Skerk, J. Vranes Evaluation of direct etest and disk diffusion methods on blood cultures versus CLSI broth microdilution reference method for ceftaroline E. Cercenado* (Madrid, Spain), C. Sánchez-Carrillo, B. Gama, M. Rodriguez-Creixems, A. Burillo, E. Bouza eP199 Use of different disinfectants, phytochemicals and antibiotics to inactivate resistant S. aureus strains adhered to different materials I. Gomes* (Porto, Portugal), J. Malheiro, A. Abreu, F. Mergulhão, M. Simões eP200 Virulence profiles, antimicrobial resistance and genetic diversity of Escherichia coli strains of urosepsis and soft tissue infections from India and septicaemia isolates from Germany A. Ranjan* (Hyderabad, India), A. Hussain, N. Ahmed 100 24th ECCMID / Barcelona Final Programme Viewing Stations EPOSTER VIEWING: Polymyxins and carbapenem-resistant bacteria eP206 High-dose intravenous colistin methanesulfonate therapy is associated with high rates of nephrotoxicity; a prospective cohort study from Saudi Arabia W.A. Alfahad* (Riyadh, Saudi Arabia), A.M. Baadani, S.K. Aldalbhi, M.M. Shoukri, A.A. Almitwazi, A.M. Albaraak, A.S. Omrani eP207 Intravenous colistin for the treatment of carbapenem-resistant Acinetobacter infections (CRA): a retrospective review of 86 patients in a regional hospital in Hong Kong T.S. Kwong* (Hong Kong, China), T.C. Wu, W. Lam, M.Y. Chu, H.C. Tang, S.Y. Chan, W.M. Ting ePoster Viewing eP217 Combined therapy with in vitro synergy for the treatment of colistin-resistant Enterobacteriaceae-KPC infections S. De Gregorio, M. Nastro, N. Pozzi, C. Rodriguez, C. Vay, A. Famiglietti, D. Stecher* (Buenos Aires, Argentina), M. Foccoli Concordance of empiric antibiotic therapy with cultures from percutaneous cholecystostomy and outcomes of patients with acute cholecystitis: a cohort study Y. Brodsky, O. Nitzan* (Afula, Israel), D. Hershko, H. Edelstein, B. Chazan eP218 No association between colistin daily dose and clinical outcomes with low colistin dosing L. Farbman* (Tel Aviv, Israel), E. Goldberg, D. Yahav, J. Bishara, L. Leibovici, M. Paul Does timely antimicrobial administration improve mortality in septic patients admitted to ICU? R. Pai* (London, United Kingdom), D. Tyl, A. Gonzalez-Ruiz, M. Sange eP219 Prudent prescribing versus prompt sepsis treatment: using resistance surveillance to strike the balance A. Boulos, H. Brennan, C. Mallon, G. Ong* (Belfast, United Kingdom) eP220 Effects of inappropriate empirical antimicrobial treatment on patients with coagulase-negative staphylococcal bacteraemia S. Park* (Goyang-si, Korea), J.-W. Chung, H. Huh, S. Chae eP221 Predictors of hospital mortality among ICU patients with Gram-negative sepsis: a cohort study M. Zilberberg* (Goshen, MA, United States), A.F. Shorr, S.T. Micek, M. Kollef eP211 Intravenous polymyxin B: a retrospective cross-sectional study to evaluate its use and clinical outcomes W.H.W. Ng* (Singapore, Singapore), Y. Yao, J.X.H. Li eP212 Effect of a probiotic preparation (VSL#3) on Klebsiella KPC enteric colonisation A. Perrella* (Naples, Italy), C. Sbreglia, P. Bellopede, G. Amato, M. Conte, O. Perrella Viewing Stations EPOSTER VIEWING: Empirical antibiotic treatment eP213 eP214 eP215 Optimisation of the length of empirical antimicrobial therapy in patients with cancer and febrile neutropenia A. Martin-Pena* (Seville, Spain), M. Aguilar-Guisado, J. Falantes, M.L. Martino, R. Parody, I. Montero, J. Gónzalez-Campos, I. Espigado, J.M. Cisneros Developing a score to shorten the time to initiation of appropriate therapy for extensively drug-resistant Gram-negative bacilli and avoid unnecessary use of polymyxins I. Vitkon-Barkay, M. Yekutiel, E.M. Martin, K.N.F. De Almeida, D. Nestor, G. Geva, J. Volfson, T. Azouri, K.S. Kaye, D. Marchaim* (Zerifin, Israel) Delay in diagnosis of infective endocarditis in Japan T. Fukuchi* (Kobe, Japan), K. Iwata, G. Ohji Viewing Stations EPOSTER VIEWING: The evolution of colistin resistance eP222 The evolution of high colistin resistance in Pseudomonas aeruginosa N. Jochumsen, R.L. Marvig, S. Damkiær, R.L. Jensen, L. Jelsbak, S. Molin, A. Folkesson* (Fredriksberg, Denmark) eP223 The mgrB gene as a key target for acquired resistance to colistin in Klebsiella pneumoniae L. Poirel* (Fribourg, Switzerland), A. Jayol, M.V. Villegas, S. Turkoglü, P. Nordmann 24th ECCMID / Barcelona Final Programme Posters Appropriateness of antimicrobial therapy in patients with healthcare-associated bacteraemia E. Van Hauwermeiren, P. Lanza, A. Zoncada, S. Lorenzotti, F. Zacchi, C. Fornabaio, L. Galli, M. Fornaciari, A. Pan* (Cremona, Italy) Chairs, Speakers & Authors eP210 eP216 101 Exhibition eP209 Effectiveness of double-carbapenem regimen in carbapenem and colistin-resistant Klebsiella pneumoniae bloodstream infections: correlation with in vitro analysis A. D’Abramo* (Rome, Italy), A. Oliva, M.T. Mascellino, C. D’Agostino, M. Iannetta, C. Gallinelli, C.M. Mastroianni, V. Vullo General Information eP208 ePosters Saturday, 10 May 2014 - Tuesday, 13 May 2014 ePoster Viewing Saturday, 10 May 2014 - Tuesday, 13 May 2014 eP224 eP225 eP226 Resistance to colistin associated with an identical mutation in protein PmrB among clonally-unrelated Klebsiella pneumoniae isolates L. Poirel* (Fribourg, Switzerland), A. Jayol, M.V. Villegas, M. Ozdamar, A. Brink, P. Nordmann The role of outer membrane protein loss in colistin-resistant Klebsiella pneumoniae ST258 and Enterobacter asburiae clinical isolates B. Kocsis* (Budapest, Hungary), B. Kádár, A. Fullár, P. Felso, B. Kocsis, K. Böddi, K. Kristóf, Á. Tóth, K. Nagy, D. Szabó Phenotypic and molecular characterisation of colistin-resistant A. baumannii clinical isolates from Greek hospitals K. Dafopoulou, I. Kristo, O. Zarkotou, A. Poulou, V. Gogou, C. Hadjichristodoulou, A. Tsakris, S. Pournaras* (Athens, Greece) eP227 A comparison of the diagnostic value of MRI and FDG-PET/CT in suspected spondylodiscitis C. Smids, I.J.E. Kouijzer, F.J. Vos, T. Sprong, A.J.F. Hosman, J.W.J. De Rooy, W.J.G. Oyen, C.P. Bleeker-Rovers* (Nijmegen, The Netherlands) eP228 Is preoperative joint fluid aspiration useful for the diagnosis of periprosthetic joint infection? A. Bicart See, E. Bonnet* (Toulouse, France), J. Lourtet, T. Pollon, J. Remi, C. Livideanu, P. Marlin, L. Gautie, M. Felice, G. Giordano eP229 Evaluation of BacT/Alert FAN blood culture bottles inoculated with sonication fluid for the diagnosis of implant-associated infection A. Siverio* (Barcelona, Spain), M. Salvadó, C. Heredia, D. Pérez, A. Alier, L. Sorli, J.P. Horcajada, L. Puig, J. Gómez, M. Portillo Bordonabe eP230 eP231 Matrix-assisted laser desorption ionization time of flight mass spectrometry and prosthetic joint infection T. Peel* (Melbourne, Australia), N.C. Cole, B.L. Dylla, R. Patel Use of molecular techniques in the microbial diagnosis of infectious spondylodiscitis H. Jacquier* (Paris, France), V. Fihman, F. Meunier, V. Delcey, R. Kaci, J. Laredo, F. Lioté, F. Zadegan, E. Cambau, B. Berçot 24th ECCMID / Barcelona Final Programme Viewing Stations EPOSTER VIEWING: Antifungal drug susceptibility and resistance eP232 Echinocandin MICS against Candida species at hospitals that routinely perform susceptibility testing of bloodstream isolates G. Eschenauer, M.H. Nguyen, S. Shoham, J. Vazquez, A. Morris, C. Kubin, P. Carver, K. Hanson, S. Chen, C.J. Clancy* (Pittsburgh, United States) eP233 A 7-year review of Candida isolates and antifungal susceptibility from clinical specimens in Alberta, Canada J. Kanji* (Edmonton, Canada), A. Bull, S. Shokoples, J. Fuller eP234 Low rate of cryptic species and antifungal resistance in Candida isolates causing candidaemia in Madrid L.J. Marcos-Zambrano, P. Escribano, P. Muñoz, E. Bouza, J. Guinea Ortega* (Madrid, Spain) eP235 Species distribution and antifungal susceptibilities of bloodstream Candida sp. from the Asia-Pacific region T.Y. Tan* (Singapore, Singapore), L.Y. Hsu, M.M. Alejandria, T. Chinniah, P. Kiratisin, J.H. Shin, T.T.N. Tran, A.L. Tan, L.S.Y. Ng eP236 Comparative evaluation of a new commercial colorimetric microdilution assay (SensiQuattro Candida EU) with E-test and EUCAST broth microdilution for susceptibility testing of invasive Candida isolates H.L. Köhling* (Essen, Germany), B. Willinger, J. Buer, P.-M. Rath, J. Steinmann eP237 CAS5 influences the activity of fluconazole against Candida albicans E.M. Vasicek, E.L. Berkow* (Memphis, TN, United States), S.A. Flowers, K.S. Barker, P.D. Rogers eP238 Is micafungin uniformly active against Candida albicans biofilms showing different degrees of metabolic activity? L.J. Marcos-Zambrano, P. Escribano, E. Bouza, J. Guinea Ortega* (Madrid, Spain) eP239 Candidaemia in Bulgaria: an open follow-up multicentre survey A. Kouzmanov* (Sofia, Bulgaria), Z. Ivanova, I. Philipova, T. Velinov, T. Kantardjiev Viewing Stations EPOSTER VIEWING: Diagnosis of osteoarticular infection 102 ePoster Viewing eP242 Echinocandin failure case due to a yet unreported FKS mutation in Candida krusei R. Jensen* (Copenhagen, Denmark), U. Justesen, A. Rewes, D. Perlin, M. Arendrup eP243 Twofold point mutations in Candida albicans FKS1 gene leading to echinocandin resistance after long-term treatment K. Heidrich, R. Krause* (Graz, Austria), M. Hoenigl, C. Lass-Floerl, W. Buzina eP244 eP245 eP246 eP247 eP248 Identification of novel transcription factors associated with azole resistance in Aspergillus fumigatus E. Davies* (Manchester, United Kingdom), M. Fraczek, P. Bowyer, R. Collins, M. Bromley Surveillance of azole resistance among environmental isolates of Aspergillus fumigatus species complex in a general hospital in Madrid T. Pelaez Garcia* (Madrid, Spain), S. Álvarez-Pérez, M.E. García, J.L. Blanco, B. Gama, E. Mellado, E. Bouza Aspergillus fumigatus with prior azole exposure decreases amphotericin B sensitivity in vitro R. Rajendran* (Glasgow, United Kingdom), C. Williams, B. Jones, G. Ramage Investigation of primary clinical samples and azole-resistant isolates of immunocompromised patients for cyp51A mutations in Aspergillus fumigatus using established and a novel TR46 PCR assays B. Spiess* (Mannheim, Germany), P. Postina, A. Hamprecht, J. Vehreschild, C. Lass-Flörl, M. Hönigl, P.-M. Rath, T. Miethke, W.-K. Hofmann, D. Buchheidt Occurrence and molecular characterisation of triazole-resistant Aspergillus fumigatus in outdoor and hospital environment in Kuwait Z. Khan* (Safat, Kuwait), S. Ahmad, L. Joseph, A. Theyyathel, F. Hagen, J.F. Meis, J.F. Meis eP250 Molecular identification and antifungal susceptibility of Aspergillus clinical isolates from 11 hospitals in Korea J.H. Shin* (Gwangju, Korea), S.H. Kim, M.J. Choi, Y.J. Park, H.S. Lee, S.J. Jang eP251 Antifungal susceptibility and outcome of invasive fungal infection: a 10-year retrospective electronic chart review T. Wrba, B. Willinger, W. Graninger, M. Diab-Elschahawi, E. Presterl* (Vienna, Austria) eP252 First Danish report of TR34/L98H A. fumigatus in three non-cystic fibrosis patients despite apparent lack of resistant isolates in recent soil samples K.M.T. Astvad* (Valby, Denmark), R.H. Jensen, T.M. Hassan, E.G. Mathiasen, G.M. Thomsen, U.G. Pedersen, M. Christensen, M.C. Arendrup eP253 Candida parapsilosis antifungal resistance: a Portuguese surveillance survey J. Branco, A. Silva-Dias, C. Martins-Cruz, N. Gomes, A. Pinto-Silva, R. Silva, T. Gonçalves, C. Pina-Vaz, A.G. Rodrigues, I.M. Miranda* (Porto, Portugal) eP254 Performance in EQA for antifungal susceptibility from 2007 to 2013 by United Kingdom national external quality assessment service S. Seaton* (London, United Kingdom), E. Johnson, E. Fagan, C. Walton eP255 In vitro antifungal synergy testing against spores and hyphae of Mucorales and Fusarium species A. Bakossi, M. Siopi, J. Meletiadis, G.L. Petrikkos* (Athens, Greece), M. Drogari-Apiranthitou eP256 Correlation of early trough levels (day 4) with steady-state posaconazole plasma concentrations – a cohort study M. Hoenigl* (Graz, Austria), W. Duettmann, B. Huber-Krassnitzer, J. Wagner, J. Prattes, K. Troppan, K. Seeber, R.B. Raggam, A. Wölfler, R. Krause eP257 Determination of susceptibility breakpoints for posaconazole and Aspergillus fumigatus using a pharmacokinetic-pharmacodynamic model A. Elefanti* (Athens, Greece), E. Mavridou, J. Mouton, P.E. Verweij, J. Meletiadis 24th ECCMID / Barcelona Final Programme Posters Antifungal susceptibility profiles of pathogens of invasive candidiasis in Russia E. Raush* (St. Petersburg, Russia), N. Vasilyeva, E. Shagdileeva, N. Klimko Simple, low-cost molecular detection of TR34/ L98H mutations in cyp51A gene for rapid detection of triazole-resistant Aspergillus fumigatus isolates S. Ahmad* (Safat, Kuwait), Z. Khan, L. Joseph, F. Hagen, J. Meis, J. Meis Chairs, Speakers & Authors eP241 eP249 Exhibition Impact of the exposure of clinically relevant yeasts to agricultural azoles in terms of antifungal resistance I. Faria-Ramos* (Porto, Portugal), P. Ribeiro-Tavares, J. Neves-Maia, E. Ricardo, I.M. Miranda, L.M. Estevinho, C. Pina-Vaz, A.G. Rodrigues 103 General Information eP240 ePosters Saturday, 10 May 2014 - Tuesday, 13 May 2014 ePoster Viewing Saturday, 10 May 2014 - Tuesday, 13 May 2014 eP258 In vitro evaluation of the efficacy of voriconazoleanidulafungin combination against azolesusceptible and -resistant Aspergillus fumigatus strains with a novel pharmacokineticpharmacodynamic (PK-PD) model M. Siopi* (Athens, Greece), N. Siafakas, L. Zerva, J. Meletiadis eP266 Impact of a hydrogen peroxide vapour-based decontamination method on the infectivity and detectability of feline caliciviruses as surrogates for human noroviruses S. Fister* (Vienna, Austria), F. Allerberger, M. Wagner, P. Rossmanith eP259 Optimising antifungal combination therapy of voriconazole+amphotericin B against Aspergillus fumigatus using a pharmacokineticpharmacodynamic (PK-PD) model M. Siopi* (Athens, Greece), N. Siafakas, L. Zerva, J. Meletiadis eP267 Assessing the efficacy of two commonly used disinfecting agents in hospital isolation rooms M. Smith* (Kilmarnock, United Kingdom), W.G. Mackay, K. Smith, C. Woodall, C.L. Williams, R.G. Masterton eP268 HyperDRYMist® system of 99T: major impact in reducing surface bacterial and fungal contamination C. Dalla Valle, V. Monzillo, D. Scevola* (Pavia, Italy), P. Marone eP269 Using electrolysed water to clean near-patient sites: is disinfectant better than detergent? M. Stewart* (Glasgow, United Kingdom), S.J. Dancer, A. Bogusz, J. Hunter, I. Devanny, B. Yip, D. Reid, C. Robertson eP270 Environmental sampling of air and surfaces on hospital wards. What does it tell us? T. Claro* (Dublin, Ireland), M. O’Reilly, H. Humphreys Effects of a syphon disinfection device on colonisation with multiresistant Pseudomonas aeruginosa in sinks on a tertiary care centre ICU E.H.R. Van Essen* (Leiden, The Netherlands), M.G.J. De Boer, R.B.P. De Wilde, H.C.M. Dogterom-Ballering, K.E. Veldkamp, E. De Jonge eP271 Antimicrobial resistant Gram-negative bacilli in the ICU: examining the interplay between patient colonisation and environmental contamination H. McDermott* (Dublin, Ireland), M. Scally, H. Humphreys, D. Fitzgerald-Hughes Bath basins in healthcare settings from Europe and North America as common reservoirs for multi-drug resistant organisms B. Ackerman, K.S. Kaye, D. Marchaim* (Zerifin, Israel) eP272 Stethoscope bacterial contamination and cleaning practices among healthcare workers in a district general hospital N. Virgincar* (Reading, United Kingdom), H. Aubrey-Jones, J. Hayward, J. Pritchard, L. Hosie eP273 Endoscopy rinse water testing: 5 years’ experience A. Marek* (Glasgow, United Kingdom), M. Peat, A. Connell, I. Gillespie, A. Hamilton, D. Shaw, A. Stewart, K. Hamilton, I. Smith, A. Smith eP274 Persistence of microbial contamination on transvaginal ultrasound probes despite low-level disinfection procedure F. MZali* (Bordeaux, France), S. Leroy, Y. Mekki, C. Quentin-Noury, M. Kann eP260 Reported cardiovascular events during echinocandin pharmacotherapy J. Cleary* (Brandon, United States), S.T. King, K.R. Stover eP261 In vivo evaluation of cardiac effects of caspofungin K.R. Stover* (Jackson MS, United States), J.D. Cleary Viewing Stations EPOSTER VIEWING: Assessing and decreasing environmental contamination eP262 eP263 eP264 eP265 Decontamination of hospital surfaces using an air plasma multi-jet T. Claro* (Dublin, Ireland), O. Cahill, N. O’Connor, S. Daniels, H. Humphreys Efficacy of HyperDRYMist® micro-nebulised hydrogen peroxide in reducing hospital-acquired infections M. Ferrari* (Lodi , Italy), A. Bocconi, A. Anesi, C. Garzoni 104 24th ECCMID / Barcelona Final Programme ePoster Viewing Saturday, 10 May 2014 - Tuesday, 13 May 2014 Do we really need to coat the novel silicone intranasal splints with antibiotics? Dividing fact from fiction Z. Ciftci, M. Aydin* (Tekirdag, Turkey), A.D. Kaya, G. Varol Saracoglu, M. Deniz, E. Gultekin eP278 eP279 Copper-coated textiles with potent antimicrobial activity against methicillin-resistant Staphylococcus aureus I. Galani, G. Priniotakis, K. Orlandou, I. Chronis, A. Tzerachoglou, G. Petrikkos* (Athens, Greece), M. Souli Antimicrobial activity of copper-nickel-coated door handles: a blind randomised controlled trial in clinical setting E.A. Idelevich* (Münster, Germany), I. Sielemann, G. Peters, C. Gebert, K. Becker eP280 Can toy wash and disinfection reduce bacteria load and sickness in day care centres? T. Ibfelt* (Copenhagen, Denmark), L. Andersen eP281 Pneumatic transport systems (PTS) are prone to contamination with multiresistant organisms – lessons learned from an Acinetobacter spp. (GIM-1) pseudooutbreak at a large university hospital M. Herrmann* (Homburg/Saar, Germany), S. Jungmann, A. Dawson, A. Halfmann, M. Kaase, S. Gatermann, L. Von Müller, B. Gärtner eP282 eP283 Correlation of the safety climate in the internal medicine departments and intensive care units (ICUs) of a general hospital with the rate of healthcare-associated infections A. Karaiskou, A. Arvaniti, E. Trikka-Graphakos, S. Sympardi* (Corfu, Greece), A. Kyratsa, F. Klouva-Molyvdas Prevalence of E. coli and coliform bacteria in children’s playground sand in Austria A. Badura* (Graz, Austria), G. Feierl, E. Leitner, J. Luxner, L. Masoud-Landgraf, H. Galler, R. Riedl, A.J. Grisold Street-vending foods: an underestimated vehicle of bacteria carrying virulence factors and antibiotic resistance genes J. Campos* (Porto, Portugal), J. Gil, J. Mourão, L. Peixe, P. Antunes eP286 Water quality of swimming pools: a growing public health concern M.J. Neuparth, A. Gomes, S. Alves, C. Diniz, N. Ferreiro, J. Proença, S. Quinteira* (Vila Nova Famalicao, Portugal) eP287 External quality assessment for laboratory testing of hospital tap water – findings from an international pilot scheme N. Patel* (London, United Kingdom) Viewing Stations EPOSTER VIEWING: Basic science: biofilm pathophysiology eP288 Setting up a NADH oxidase (NOX)-based assay to quantify antibiotic activity in pneumococcal planktonic cultures and biofilms N.M. Vandevelde* (Brussels, Belgium), Y. Dias Iglesias, P.M. Tulkens, F. Van Bambeke eP289 Anti-biofilm activity secreted by Staphylococcus aureus against Staphylococcus epidermidis M. Tilotta* (Rome, Italy), R. Papa, A. Cellini, L. Selan, M. Artini eP290 Evidence for the involvement of Staphylococcus epidermidis LPXTG surface protein SesC in biofilm formation and catheter-related infections L. Khodaparast* (Leuven, Belgium), L. Khodaparast, M. Shahrooei, J. Van Eldere eP291 Alpha-toxin production by clinical wound isolates of Staphylococcus aureus correlates with mucosal biofilm formation M. Anderson* (Minneapolis, United States), E. Schaaf, H. Wang, J. Johnson, M. Peterson eP292 Serologic responses against biofilm-associated Staphylococcus epidermidis cell surface structures during prosthetic joint infections H. Ocal* (Hamburg, Germany), G. Franke, H. Büttner, M. Kohns, J.U.M.I. Klettke, T. Lange, D. Mack, H. Rohde 24th ECCMID / Barcelona Final Programme 105 ePosters eP277 eP285 Posters Risk of HIV and hepatitis C infection related to endocavitary ultrasound probe exposure T. Bénet* (Lyon, France), J. Ritter, P. Vanhems High presence of Enterobacteriaceae and other microorganisms isolated from meat products L. Ruiz* (Barcelona, Spain), M.J. Pons, C. Gomes, S. Martinez Puchol, N. Palma, T.J. Ochoa, J. Ruiz Chairs, Speakers & Authors eP276 eP284 Exhibition A novel approach for in vitro evaluation of the potential risk of patient contamination during endovaginal ultrasound examinations F. MZali* (Bordeaux, France), S. Leroy, M. Kann, C. Quentin-Noury General Information eP275 ePoster Viewing Saturday, 10 May 2014 - Tuesday, 13 May 2014 eP293 eP294 eP295 eP296 Identification of a core microbiome of endotracheal tubes associated with Pseudomonas aeruginosa and/or Staphylococcus epidermidis A. Hotterbeekx* (Wilrijk, Belgium), B.B. Xavier, P. Moons, C. Lammens, M. Ieven, P. Jorens, E. Vandenbroeck, S. Kumar-Singh, H. Goossens, S. Malhotra-Kumar eP302 Use of a microfluidic system to study biofilm formation in pathogenic Escherichia coli Y.D.N. Tremblay, P. Vogeleer, J. Harel, M. Jacques* (St-Hyacinthe, Canada) eP303 Investigation of biofilm formation recovered from endotracheal tubes among intensive care unit paediatric patients M.J.C. Salles* (São Paulo, Brazil), G.F. Da Costa Leite, R.Y. Koto, T.O. Ferreira, M.J. Mimica, C.B. Silva, A.P.I. Fonseca Souza, S. Nigro, M.H. Yano Investigation of the effect of different temperature and acidic conditions on biofilm structure of Salmonella enterica serotype Virchow by FTIR spectroscopy M.N. Badali* (Ankara, Turkey), N. Igci, M. Diani, M. Akçelik, N. Akçelik eP304 Polymicrobial biofilms by diabetic foot clinical isolates C. Mottola* (Lisbon, Portugal), J.J. Mendes, J. Melo-Cristino, P. Cavaco-Silva, L. Tavares, M. Oliveira Effect of supernatants from selected periopathogen cultures on ATP levels in human gingival fibroblasts A.K. Szkaradkiewicz, T.M. Karpinski, I. Chudzicka-Strugala* (Poznan, Poland), O. Goslinska-Kuzniarek eP305 Biofilm production, adherence capacity, cellular surface hydrophobicity and secreted aspartyl protease activity of different species of the genus Candida isolated from haemocultures M.T. Blanco-Blanco* (Badajoz, Spain), M.A. Galán, M.T. Blanco, L. Lucio, C. Pérez-Giraldo, A.C. GómezGarcía BCR1 independent biofilm formation of outbreak related Candida parapsilosis isolates from nosocomial bloodstream infections S. Pannanusorn* (Stockholm, Sweden), T. Schön, J. Morschhäuser, U. Römling Viewing Stations EPOSTER VIEWING: Biomarkers eP297 Assessing composition and micromorphology of biofilm in urinary catheters I. Caola, F. Tessarolo* (Mattarello, Italy), M. Leonardi, T. Cai, F. Piccoli, G. Nollo, G. Malossini, R. Bartoletti, P. Caciagli eP306 Diagnostic and prognostic value of serum presepsin in cirrhotic patients with spontaneous bacterial peritonitis H. Okasha* (Alexandria, Egypt), A. Elgohary, A. Abd El Moety, A. Elbadawy eP298 Molecular investigation of bacterial communities on intravascular catheters: not just Staphylococcus anymore L. Zhang* (Brisbane, Australia), G. John, M. Morrison, L. Krause, C. Rickard eP307 The superiority of procalcitonin versus C-reactive protein in sepsis diagnosis E. Puca* (Tirane, Albania), P. Pipero, A. Pilaca, G. Stroni, E. Qyra, T. Kalo, E. Puca, G. Huti, K. Allajbeu, D. Kraja eP299 Regulatory systems of Streptococcus mutans in biofilm formation on injured heart valves S.C. Jung, J.S. Chia* (Taipei, Taiwan) eP308 eP300 Development of a novel in vitro device that simulates the real life of the biofilm formation on catheters under both static and dynamic systems M. El-Azizi* (Cairo, Egypt) Comparison of molecular and glutamate dehydrogenase tests in a multistep diagnostic algorithm in the laboratory diagnosis of Clostridium difficile E. Ho* (Antwerp, Belgium), W. Van Nijnatten, I. Mermans, M. Ieven eP309 Immunological predictors of nosocomial infection in intensive care O. Dzupova* (Prague, Czech Republic), A. Davidova, O. Beran, J. Benes, M. Holub eP301 Characterisation of a quroum sensing system in Acinetobacter baumannii that enhances the pili assembly and biofilms proficiency L.M. Luo, L.J. Wu, Y.L. Xiao, D. Zhao, Y.C. Huang, M. Kang, Q. Zhang, Y. Xie* (Chengdu, China) 106 24th ECCMID / Barcelona Final Programme ePoster Viewing eP312 eP313 eP314 eP315 Screening of potential serological markers for diagnosis of Pneumocystis pneumonia (PCP) F. Esteves* (Lisbon, Portugal), S. Calé, B. De Sousa, J. Gaspar, R. Badura, F. Antunes, M. Olga Metabolic biomarkers for treatment outcome of sepsis and injury-related SIRS O. Rzhepishevska* (Umea, Sweden), S. Gouveia, R. Pinto, M. Nording, J. Sunden-Cullberg, Å. Johansson Host biomarkers of inflammation and endothelial activation as an alternative to chest x-ray among Tanzanian children with clinical pneumonia: a cohort study V. D’Acremont, K.T. Hayford, L.K. Erdman, M. Kilowoko, E. Kyungu, S. Philippina, L. Alamo, W. Sangu, B. Genton* (Lausanne, Switzerland), K. Kain Clinical usefulness of infection biomarkers in neutropenic SIRS patients in standard care wards F. Ratzinger* (Vienna, Austria), I. Tsirkinidou, M. Schuardt, K. Eichbichler, H. Haslacher, T. Perkmann, H. Burgmann Use of avibactam to detect ambler class A carbapenemases and OXA-48 in Enterobacteriaceae N. Porres-Osante, C. De Champs, H. Dupont, C. Torres, H. Mammeri* (Amiens, France) eP319 Quantitative modified Hodge test (Q-MHT) interpretation for the detection of Klebsiella pneumoniae carbapenemase (KPC) in Enterobacteriaceae. Is that possible? A.P. Cury, J. Nobrega de Almeida Júnior, M. Maffucci, H. Hehl Caiaffa Filho, F. Rossi* (São Paulo, Brazil) eP320 Combined use of the modified Hodge test and Carba NP test for the detection of carbapenemase production in Gram-negative bacteria W. Song* (Seoul, Korea), S.H. Jeong, S.G. Hong, J.S. Kim, H.S. Kim eP321 Pilot evaluation of the BLACTA test for predicting 3rd generation cephalosporin resistance (3GCR) in Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca and Proteus mirabilis from blood B.M. Willey* (Toronto, Canada), X. Trimi, P. Lo, S.M. Poutanen eP322 Evaluation of ChromID®CARBA and ChromID®OXA-48 media for the detection of carbapenemase-producing Acinetobacter spp P. Higgins* (Cologne, Germany), L. Devigne, H. Seifert eP323 Evaluation of the new strip E-test KPC MP/MPB for K. pneumoniae carbapenemases detection in comparison with Liofilchem® KPC strips on a large Enterobacteriaceae collection D. Halimi, R. Noblecourt, M. Pompilio, V. Sauvonnet, G. Durand, G. Zambardi, R. Martelin* (La BalmeLes Grottes, France) eP324 Accuracy of susceptibility test methods for the detection of meropenem resistance in Gramnegative bacilli F. Hurren* (Melbourne, Australia), J. Montgomery, J. Wang, J. Ellem Viewing Stations EPOSTER VIEWING: Diagnostics: detection of ESBLs and carbapenemases eP316 eP318 Improving screening for carbapenemaseproducing organisms: evaluation of two chromogenic media and confirmatory disc diffusion assays G.L. Vanstone* (London, United Kingdom), A. Lyons, A. Morkowska, A. Williams, R. Smith, I. Balakrishnan 24th ECCMID / Barcelona Final Programme Posters Role of CD64 on monocytes and HLA-DR on neutrophils in the diagnosis of sepsis and outcome of critically ill patients M. Papadimitriou Olivgeris* (Patras, Greece), K. Lekka, K. Zisimopoulos, I. Spiliopoulou, K. Filos, E. Anastassiou, F. Fligou, M. Karakantza, M. Marangos Phenotypic markers to suspect OXA-163 carbapenemase producers (OXA-163 PE) in species of Enterobacteriaceae: a OXA-48 related carbapenemase with low-level temocillin resistance F. Pasteran* (Buenos Aires, Argentina), O. Veliz, E. Albornoz, C. Lucero, S. Gomez, G. Romero Thomas, OXA-Arg Group, A. Corso 107 Chairs, Speakers & Authors eP311 eP317 Exhibition Procalcitonin in patients with cancer: role of biomarker-assisted diagnosis for bacterial infections, SIRS and sepsis syndrome J. Torres Isasiga, J. Teperman, Y. Dubrovskaya, R. Press, A. Safdar* (New York, United States) General Information eP310 ePosters Saturday, 10 May 2014 - Tuesday, 13 May 2014 ePoster Viewing Saturday, 10 May 2014 - Tuesday, 13 May 2014 eP325 Use of temocillin for identification of class D carbapenemases M. Cordovana* (Bologna, Italy), M.V. Tamburini, G. Roncarati, A. Berlingeri, S. Ambretti, C. Foschi, P. Gaibani, M.P. Landini eP326 Phenotypic screening of carbapenemase production in carbapenem-resistant Klebsiella pneumoniae and Pseudomonas aeruginosa strains E. Protonotariou, P. Dimitriadis, O. Vasilaki, D. Papadopoulou, S. Koufos, S. Varlamis* (Thessaloniki, Greece), P. Tsiavi, S. Metallidis, E. Diza, L. Skoura eP333 A retrospective evaluation of the rapid biorad BLACTA test to detect 3rd generation cephalosporin resistance (3GCR) in Enterobacteriaceae (ENT) B.M. Willey* (Toronto, Canada), D.A. Boyd, X. Trimi, A. Tsang, O. Oleung, S. Kim, I. Manji, P. Lo, M. Mulvey, S.M. Poutanen eP334 Evaluation of methods for detection of VIM-1carbapenemase-producing Enterobacteriaceae in bovine minced meat M. San José, H. Hasman, J. Fischer, Y. Agerso, S. Schmoger, S. Jahn, K. Thomas, E. Guiral, R. Helmuth, B. Guerra Roman* (Berlin, Germany) eP327 Further validation of Blue-CARBA, a recently described quick and reliable method for carbapenemase detection J. Pires* (Porto, Portugal), Â. Novais, L. Silva, J. Campos, J. Botelho, I. Czobor, I. Gheorghe, L. Peixe eP335 Evaluation of the Rapid CARB Screen Diatab test for the detection of carbapenemase production in Gram-negative bacteria B. Bharathan* (London, United Kingdom), O. Oikonomou, D. Wareham, L. Phee eP328 Characterisation of carbapenemase-producing Enterobacteriaceae in colonised patients: correlation between phenotypic and molecular methods C. Casares Peinado* (Madrid, Spain), B. Plata, I. Sanchez-Romero, J. Oteo, V. Bautista, N. Lara, F. Portero eP336 Evaluation of chromid OXA-48 for the recovery of carbapenemase-producing Enterobacteriaceae from rectal swabs from hospitalised patients in Ankara, Turkey P. Zarakolu, K. Day, C. Lanyon, S. Cummings, M. Akova, J. Perry* (Newcastle-upon-Tyne, United Kingdom) eP329 Screening of carbapenemase- and ESBLproducing bacteria with the Carba NP and ESBL NDP tests, and correlation with molecular tests A. Mazzariol* (Verona, Italy), G. Petrosino, A.R. Centonze, M. Parisato, C. Castagna, M. Bragantini, G. Cornaglia eP337 Modified procedure for Carba NP detection of carbapenemase-producing bacteria directly from blood cultures A. Mazzariol* (Verona, Italy), C. Castagna, A.R. Centonze, M. Parisato, G. Petrosino, M. Bragantini, L. Maccacaro, G. Cornaglia eP330 Phenotypic detection of carbapenemaseproducing Gram-negative bacilli. Which method is better? J. Montgomery* (Melbourne, Australia), F. Hurren, J. Wang eP338 eP331 Comparative evaluation of Carba NP test and of Rosco Rapid CARB screen kit for the detection of carbapenemase in Pseudomonas aeruginosa T.D. Huang* (Yvoir, Belgium), C. Berhin, P. Bogaerts, Y. Glupczynski Detection of beta-lactamase, aminoglycosidemodifying enzyme and carbapenemase resistance biomarkers directly using MALDI-TOF Tandem MS E. Wey* (London, United Kingdom), I. Balakrishnan, T. McHugh, O. Belgacem, P. Hart eP339 The rapid CARB screen as a standardised alternative for the Carba NP test in detecting carbapenemase producing strains S. Degandt* (Kortrijk, Belgium), J. Colaert, A. Ryssaert, M. Boudewijns eP340 Discrimination of antibiotic resistant Klebsiella pneumoniae clones by Fourier Transform Infrared Spectroscopy (FTIR) C. Rodrigues* (Porto, Portugal), Â. Novais, C. Sousa, V. De Scheerder, J. Lopes, E. Machado, T. Coque, R. Cantón, L. Peixe eP332 Evaluation of rapid colorimetric tests for detection of Gram-negative rods resistant to broad-spectrum beta-lactams on primary cultures and on blood culture samples M. Dodemont* (Brussels, Belgium), A. Lambert, R. De Mendonca, S. Roisin, O. Denis, C. Nonhoff 108 24th ECCMID / Barcelona Final Programme ePoster Viewing Evaluation of the BD MAX™ CRE assay for the detection of blaKPC, blaNDM and blaOXA-48 carbapenemase genes in multidrug-resistant Gram-negative clinical isolates D. Meunier* (London, United Kingdom), K. Hopkins, S. Paule, G. Babini, N. Woodford eP350 Budget impact of a ‘de-escalation’ strategy using micafungin for the treatment of systemic Candida infections in Spain and Italy M. Casamayor, A. Van Engen, P. Musingarimi, I.A.O. Odeyemi, O. Odufowora-Sita, M. Watt* (Chertsey, United Kingdom) eP351 Medical management of prosthetic valve endocarditis caused by Candida parapsilosis D. Mukherjee* (Kolkata, India) Early appropriate antifungal therapy improves outcomes of patients with candidaemia in intensive care unit P.Y. Chen* (Taipei, Taiwan), H.Y. Sun, Y.C. Chuang, W.H. Sheng, Y.C. Chen, S.C. Chang eP352 Retrospective cohort study comparing the clinical efficacy and safety of micafungin versus caspofungin for treatment of candidaemia and invasive fungal disease H. Habayeb* (Chertsey, United Kingdom), C. Grundy, M. Barker, S. Van De Velde Impact of initial antifungal therapy on the outcome of Candida glabrata bloodstream infections M. Puig-Asensio* (Barcelona, Spain), P. Merino, P. Martín-Dávila, M. Fernández-Ruiz, J.M. Aguado, M. Cuenca-Estrella, B. Almirante eP353 Echinocandins in unselected critically ill patients with either proven or suspected invasive candidiasis: a single-centre prospective cohort 4-year study R. Bruyere, C. Vigneron, F. Dalle, S. Prin, J.P. Quenot, C. Leon, P. Charles* (Dijon, France) High-dose micafungin therapy for Candida endophthalmitis K. Furukawa* (Tokyo, Japan), Y. Natori, K. Ohkoshi eP354 Is Clostridium difficile infection (CDI) correlated to candidaemia? R. Murri* (Rome, Italy), M. Fantoni, G. Scoppettuolo, G. Ventura, M. Fabbiani, R. Cauda Skin, eye and heart involvement in candidaemic patients M. Dizbay* (Ankara, Turkey), O. Karasahin, I.I. Balkan, G.R. Yilmaz, T. Guven, F. Yilmaz Karadag, S. Kose, M. Yemisen, M. Turken, S. Ozger eP355 Clinical features of candidaemia in the AsiaPacific region: a preliminary analysis M. Chayakulkeeree* (Bangkok, Thailand), T.Y. Tan, L.Y. Hsu, R. Chaiwarith, Y.H. Chen, M. Mendoza, T.X. Phan, K. Supparatpinyo, N. Syahidah eP356 Candida tropicalis bloodstream infection: incidence, risk factors and determinants of mortality in a population-based surveillance in Spain M. Fernández-Ruiz* (Madrid, Spain), J.M. Aguado, B. Padilla, M. Puig-Asensio, M. Almela, A. Díaz-Martín, J. Rodríguez-Baño, M. Cuenca-Estrella Viewing Stations EPOSTER VIEWING: Evolving therapeutic strategies for fungal infections eP343 eP344 eP345 eP346 eP347 eP348 Poor outcomes of Candida ocular infection in candidaemia patients: analysis of 845 cases over a 15-year period H.A. Kim* (Daegu, Korea), S.Y. Ryu Intra-abdominal candidiasis is associated with high mortality, repeated surgery and echinocandin resistance, and often not initially treated with antifungal agents C.J. Clancy, R.K. Shields, M.H. Nguyen* (Pittsburgh, United States) 24th ECCMID / Barcelona Final Programme 109 Posters Impact of an antimicrobial care bundle application on management of candidaemia in a hospital of northern Italy E. Chiari* (Brescia, Italy), L. Signorini, S. Torri, G. Moioli, E. Van Hauwermeiren, G. Paraninfo, R. Stellini, F. Castelli Chairs, Speakers & Authors eP342 eP349 Exhibition Imipenem heteroresistance: high prevalence among Enterobacteriaceae KPC producers C.S. Nodari, V.B. Ribeiro, A. Barth* (Porto Alegre, Brazil) General Information eP341 ePosters Saturday, 10 May 2014 - Tuesday, 13 May 2014 ePoster Viewing Saturday, 10 May 2014 - Tuesday, 13 May 2014 eP357 KPC-producing Klebsiella pneumoniae colonisation and infection predispose to Candida spp. isolation and selection of non-albicans species M. Papadimitriou-Olivgeris* (Patras, Greece), A. Spiliopoulou, F. Fligou, P. Manolopoulou, I. Spiliopoulou, V. Dodou, K. Filos, E. Anastassiou, M. Marangos, M. Christofidou eP358 Is timely and appropriate antifungal drug treatment enough for survival of adult cases with candidaemia? T. Yildirmak, H. Gedik* (Istanbul, Turkey), S. Funda, E. Fatma Nur, G. Aysegul eP359 Risk factors for the mortality in candidaemia cases O. Guzel Tunccan* (Ankara, Turkey), M. Dizbay, K. Hizel, E. Senol, D. Arman, F. Ulutan, F. Aktas eP360 Voriconazole in primary treatment of invasive Aspergillosis – an observational study; correlation of efficacy with C-reactive protein and procalcitonin levels L. Drgona* (Bratislava, Slovakia), J. Mikula, E. Bojtarova, D. Horvathova, J. Chudej, T. Guman, N. Stecova, D. Kapusta, P. Kukol, K. Sobonova eP362 Safety of micafungin as antifungal prophylaxis in high-risk liver transplantation patients: results from a randomised, open-label, multi-centre study L. Fischer* (Hamburg, Germany), A. Pascher, O. Cointault, P.F. Laterre, J. De Waele, U. Cillo, C. Cervera, L. Tweddle, A. Karas, F. Saliba eP363 French real life cohort on the use of micafungin as prophylactic or curative treatment for invasive fungal infections: the Myriade study J.F. Timsit* (Paris, France), N. Milpied, G. Leverger, B. Gachot eP364 Use of antifungal drugs in real conditions of medical practice in haematology: a French multicentre prospective study (AFHEM study) J.P. Gangneux* (Rennes, France), J. El Cheikh, D. Caillot, I. Yakoub-Agha, M. Michallet eP365 110 Posaconazole plasma concentration under 0.3µg/ml is associated with an increased risk of breakthrough invasive fungal infection when on posaconazole primary prophylaxis: a four-year retrospective study N. Lerolle* (Paris, France), R. Porcher, S. Touratier, E. Raffoux, P. Ribaud, S. Bretagne, A. Bergeron, E. Azoulay, J.-M. Molina, M. Lafaurie 24th ECCMID / Barcelona Final Programme eP366 Introduction of an antifungal stewardship programme targeting liposomal amphotericin B, voriconazole, caspofungin and micafungin at a large tertiary hospital in Cambridge, England C. Micallef* (Cambridge, United Kingdom), R. Santos, S.H. Aliyu, D.A. Enoch eP367 Antifungal prescribing and invasive fungal infections in haematological malignancies other than acute myeloid leukemia J.C. Teng* (Fitzroy, Australia), M. Slavin, S. Lingaratnam, M. Ananda-Rajah, B.W. Teh, L. Worth, J. Seymour, K. Thursky eP368 Anti-mould prophylaxis in patients with superficial fusariosis on admission does not prevent invasive fusariosis A.G. Varon, M. Garnica, T. Akiti, G. Barreiros, B.M. Trope, S.A. Nouer, M. Nucci* (Rio de Janeiro, Brazil) eP369 A high percentage of patients have off-target trough voriconazole serum levels J. Guinea* (Madrid, Spain), P. Escribano, L.J. Marcos-Zambrano, M. Kestler, P. Muñoz, F. López-Fabal, M. Valerio, C. Rodríguez-González, E. Bouza eP370 Comparison of monomicrobial invasive fungal infections and mixed fungal-bacterial infections: risk factors and outcomes in 211 patients N. Kulková* (Bratislava, Slovakia), L. Micháliková, J. Brnová, V. Krcméry eP371 Invasive pulmonary aspergillosis in immunocompetent patients with severe exposure to Aspergillus spp. spores N. Klimko* (St. Petersburg, Russia), E. Desyatik, S. Khostelidi, O. Shadrivova, Y. Borzova, R. Chernopyatova, S. Ignatyeva, T. Bogomolova, A. Volkova, N. Vasileva eP372 Large invasive aspergillosis (IA) pseudooutbreak due to an intravenous (IV) formulation of acetaminophen M.T. Martin Gomez* (Barcelona, Spain), P. Barba Sunol, D. Campany Herrero, I. Ruiz Camps eP373 Multiple brain abscesses caused by Aspergillus fumigatus in a four-year old child with chronic granulomatous disease (CGD): a case report of successful antifungal treatment S. Bakheshwain* (Riyadh, Saudi Arabia), N. AlKhizzi, T. Sulaiman, N. Alkhuraish, S. Aljubran, P. Sarwat ePoster Viewing Saturday, 10 May 2014 - Tuesday, 13 May 2014 Species identification of Aspergillus isolates by DNA sequencing A. Polischouk* (St. Petersburg, Russia), Y. Mikhaylova, D. Lavnikevich, M. Rudneva, G. Chilina, T. Bogomolova eP383 Comparison of two Aspergillus real-time PCR assays with galactomannan testing of bronchoalveolar lavage fluid for the diagnosis of invasive pulmonary aspergillosis M. Hoogewerf* (Heiloo, The Netherlands), Y.J. Debets-Ossenkopp, A. Koek, A. Pettersson eP384 Comparison of qPCR with bronchoalveolar lavage fluid and serum for the diagnosis of invasive pulmonary aspergillosis J. Yu* (Beijing, China), S. Zhang, R. Li eP385 Can genotyping discriminate between invasive and colonising Aspergillus fumigatus isolates? P. Escribano, T. Peláez, E. Bouza, J. Guinea Ortega* (Madrid, Spain) eP386 A new multiplex real-time PCR for detection and identification of zygomycetes and Aspergillus spp. in human biosamples A. Polischouk* (St. Petersburg, Russia), Y. Mikhaylova, E. Belotcerkovskaya, T. Bogomolova eP387 Moulds and cystic fibrosis: what can we learn from studying lung mycobiota? L. Delhaes* (Lille, France), L. Nguyen eP388 Species identification of Fusarium by matrixassisted laser desorption ionization time-of-flight mass spectrometry L.R. Bissoli* (Rio de Janeiro, Brazil), M.Z. Aquino, M. Tomaz, A. Doi, J. Sampaio, A.S. Levin, S.F. Costa eP389 Comparison of T. rubrum specific PCR and pandermatophyte PCR with conventional methods in patients with suspected onychomycosis E. Dubljanin, I. Vujcic* (Belgrade, Serbia), I. Colovic Calovski, M.C. Arendrup, R.F. Petersen, R.H. Jensen eP390 Development of a new commercial qPCR assay to detect and differentiate dermatophyte infections of the skin, nails and hair G. Dingemans* (Maastricht, The Netherlands), M. Van den Bosch, M.P. Hayette, S. Goethel, V. Rusu, R. Sacheli, J. Meis, G. Gaajetaan, G. Simons Evaluation of a novel RIDA®GENE Pneumocystis jirovecii real-time PCR assay for the diagnosis of Pneumocystis jirovecii pneumonia A. Hiergeist, D. Martens* (Darmstadt, Germany), L. Kastl, A. Pickel, S. Gatermann eP375 Interest of adding Pneumocystis jirovecii DNA detection in nasopharyngeal aspirates for febrile pneumonia in adult patients N. Guigue* (Paris, France), J. Menotti, A. Alanio, N. De Castro, O. Peyrony, J. Le Goff, S. Bretagne eP376 Chart review of patients with low positive Histoplasma capsulatum urinary antigen results P. Ramanan, E.S. Theel, M. Abidi* (Milwaukee, United States) eP377 Evaluation of PCR electro-spray ionization-mass spectrometry (PCR/ESI-MS) fungal spectrum assay R. O’Hara, R. Barton, D. Gascoyne-Binzi* (Leeds, United Kingdom), M. Wilcox eP378 Is the frequency of Candida albicans epidemics and hyper-epidemic genotypes causing similar candidaemia in various European hospitals? L. Marcos-Zambrano, P. Escribano, M. Sanguinetti, E. Gomez G. de la Pedrosa, E. De Carolis, R. Cantón, E. Bouza, J. Guinea Ortega* (Madrid, Spain) eP379 eP380 eP381 Assessment of a QCMD proficiency programme for molecular diagnosis of systemic Candida infection E. Mcculloch* (Glasgow, United Kingdom), P.S. Wallace, C. Williams, G. Ramage, K. Lagrou, W.G. Mackay High resolution melting analysis for rapid identification of twenty-five Candida species from culture E. Nemcova* (Brno, Czech Republic), M. Cernochova, F. Ruzicka, B. Malisova, M. Vanerkova, H. Suranska, P. Nemec, T. Freiberger Use of PCR for diagnosis of invasive aspergillosis; a 3-year prospective cohort study H.C. Kung* (Taipei, Taiwan), Y.C. Chen, U.I. Wu, B.S. Ko, S.C. Chang 24th ECCMID / Barcelona Final Programme 111 Posters eP374 Chairs, Speakers & Authors EPOSTER VIEWING: Highlights from molecular mycology ePosters eP382 Exhibition Viewing Stations General Information ePoster Viewing Saturday, 10 May 2014 - Tuesday, 13 May 2014 eP391 Comparative evaluation of dermatophyte-PCR kit, with conventional methods for rapid detection of dermatophytes and identification of Trichophyton rubrum in nail specimens N. Karabicak* (Ankara, Turkey), D. Güldemir, S. Topal, N. Alem, O. Danismaz, G. Elcin, R. Durmaz eP392 Search strategy of new antifungal targets based on analysis of the protein domain and domain architecture content of fungal proteomes A. Barrera, A. Alastruey-Izquierdo* (Madrid, Spain), M. Martin, J.A. Vizcaino, I. Cuesta eP393 Multi-locus sequence typing of invasive and colonising Candida albicans isolates K. Heidrich, W. Buzina* (Graz, Austria), M. Hönigl, R. Krause eP394 Biofilm phenotypic and genotypic heterogeneity amongst Candida albicans bloodstream isolates differentially affects amphotericin B tolerance L. Sherry* (Glasgow, United Kingdom), R. Rajendran, B. Jones, C. Williams, C. Nile, G. Ramage eP395 eP396 eP397 112 Relation between biofilm formation and mtl genes in Candida tropicalis isolated from hospitalised patients M.A. Galán* (Badajoz, Spain), A. Beteta, M.T. Blanco-Blanco, A.C. Gómez-García, C. Pérez-Giraldo, M.T. Blanco Measuring C. albicans and host gene expression during intra-abdominal candidiasis of humans and mice with RNA-Seq C.J. Clancy* (Pittsburgh, United States), S. Cheng, L. Losada, S. Mounaud, W. Nierman, N. Solis, S. Filler, W. Xu, A. Mitchell, M.H. Nguyen The discordance between epidemiologically related invasive and fluconazole resistant Candida tropicalis isolates highlight the necessity to further optimise C. tropicalis multi-locus sequence typing X. Fan* (Beijing, China), M. Xiao, T.J. Gray, F.R. Kong, H. Wang, L. Zhang, Y.C. Xu 24th ECCMID / Barcelona Final Programme Viewing Stations EPOSTER VIEWING: Influenza, from bench to bedside eP398 2012-2013 winter hospitalisations at a university hospital: high morbidity associated with influenza and other acute respiratory viral infections in adults M. Bourgeois, V. Gérard, N. Ausselet, X. Muschart, I. Michaux, T.-D. Huang, P. Bogaerts, Y. Glupczynski, I. Thomas, B. Delaere* (Yvoir, Belgium) eP399 Pandemic and epidemic influenza: many similarities and few differences O. Dzupova* (Prague, Czech Republic), K. Herrmannova, M. Trojanek, Z. Blechova, M. Havlickova, H. Jirincova, A. Nagy eP400 Subtyping of influenza viruses in paediatric patients hospitalised at Bambino Gesù children’s hospital in the 2012-2013 season M. Onori* (Rome, Italy), L. Mancinelli, C. Concato, S. Chiavelli, L. Coltella, D. Menichella, C. Russo eP401 Simultaneous detection of influenza A virus subtypes using multiplex PCR C. Cicek* (Izmir, Turkey), N. Bayram, M. Anil, F. Gulen, H. Pullukcu, E.U. Saz, G. Cok eP402 Serological study for A/H2N3 avian influenza infection in Georgia A. Machablishvili* (Tbilisi, Georgia), L. Urushadze, M. Dgebuadze, M. Chubinidze, D. Tsereteli, I. Karseladze, P. Imnadze eP403 Viral aetiology of adult respiratory tract infections during the influenza season in southern Taiwan determined with PCR/ESI-MS C. Wu* (Tainan, Taiwan), H. Shih, H. Wang, C. Chou, H. Hsu, J. Wang, M. Hsieh, H. Sun, I. Su eP404 Comparative analysis of human and chicken influenza virus A(H7N9)-induced inflammatory response and virus replication kinetics K. To* (Hong Kong, China), C. Lau, J. Chan, C. Chan, H. Chen, K. Yuen eP405 Prevalence and identification of oseltamivirresistant influenza A viruses during 2009-2011 at Siriraj Hospital, Thailand N. Athipanyasilp* (Bangkok, Thailand), N. Horthongkham, B. Kaewnapan, S. Siritantikorn, W. Kantakamalakul, R. Sutthent eP407 The vaccination coverage required to establish herd immunity against influenza viruses P. Plans* (Barcelona, Spain) ePoster Viewing Saturday, 10 May 2014 - Tuesday, 13 May 2014 eP415 Treatment of acute bacterial skin and skin structure infection (ABSSSI) with dalbavancin in an outpatient setting M. Dunne* (Branford, CT, United States), S. Puttagunta, M. Wilcox, H. Boucher, G. Talbot A single-dose of oritavancin compared to 7-10 days of vancomycin: clinical response and safety in the MRSA subgroup treated in the ambulatory setting (solo trials) K. LaPensee* (Parsippany, NJ, United States), W. Fan, S. Good, H. Jiang, T. Lodise eP416 Clinical outcomes by pathogen in phase 3 studies of single dose oritavancin versus 7 to 10 days of vancomycin to treat CSSTI G. Moeck* (Saint Laurent, Canada), F.F. Arhin, H. Jiang, C. Fiset, D.C. Draghi, D.F. Sahm eP417 The PVL gene does not impact clinical response to treatment with single dose oritavancin or 7 to 10 days of vancomycin in patients with CSSTI F.F. Arhin* (Saint Laurent, Canada), G. Moeck, H. Jiang, C. Fiset, D.C. Draghi, D.F. Sahm eP418 Concordance between early (48-72 hours) and late (7-14 days post therapy) clinical response: an analysis from the solo non-inferiority clinical studies G.R. Corey* (Durham, NC, United States), S. Good, H. Jiang, G. Moeck, M. Wikler eP419 A review of the health economics and resource utilisation literature for the use of tigecycline treatment of complicated intra-abdominal infections B. Wang, Y. Chen* (Beijing, China), W. Furnback, A. Shelbaya eP420 Superinfection rates following infections’ treatment with tigecycline M. Katsiari* (Athens, Greece), Z. Roussou, E.D. Platsouka, A. Maguina eP421 Hypofibrinogenaemia associated with the administration of tigecycline I. Karaiskos* (Athens, Greece), E. Barmpouti, K. Ioannidis, L. Galani, F. Baziaka, C. Paskalis, H. Giamarellou eP422 Retrospective multi-centre experience of the effectiveness and safety with ceftaroline fosamil (CPT) therapy in patients with acute bacterial skin and skin structure infections (ABSSSI) A. Casapao* (Detroit, United States), S. Davis, V. Barr, D. Goff, K. Kaye, J. Pogue, M. Rybak eP423 Ceftaroline fosamil for treatment of CSSTI due to Staphylococcus aureus with vancomycin MICs of 1.5 to 2 mg/l: capture study experience G.E. Stein, S. Wallace, A. Jandourek* (Oakland, United States), H.D. Friedland eP410 Daptomycin in the treatment of bone and joint infections: clinical and microbiological experience at Nantes University Hospital S. Corvec* (Nantes, France), P. Bemer, L. Happi, S. Touchais, N. Asseray, M. Lefebvre, D. Navas, F. Gouin, C. Bourigault, D. Boutoille eP411 Daptomycin for cardiac infections: documented cardiac implantable electronic devices (CIED) / cardiac circulatory devices (CCD) infections and operated infective endocarditis (EI). A 43-case series P. Molmy, K. Moussa, N. Van Grunderbeeck* (Lens, France), G. Leroy, S. Barrailler, Y. Lefetz, M. Boulo, L. Guesnier, G. Fayad, O. Leroy eP412 Daptomycin for the treatment of infections in overweight/obese patients: results from the European Cubicin® outcome registry and experience A. Timerman* (Frimley, Switzerland), A. Gonzalez-Ruiz, R.A. Seaton, M. Bitzani, P. Gargalianos-Kakolyris, G. Dalekos, M. Allen, M. Bindschedler, A. Trylesinski eP413 Daptomycin treatment for Gram-positive infections in Europe: results of > 6 years’ clinical experience from EU-CORE (SM) A. Gonzalez-Ruiz* (Basel, Switzerland), K. Malizos, P. Gargalianos-Kakolyris, A. Cogo, A. Timerman, R. Utili, K. Bouylout, R. Pathan, A. Trylesinski eP414 Treatment of Gram-positive extra-pulmonary infections with daptomycin or vancomycin for ICU patients: a retrospective analysis of efficacy and nephrotoxicity P. Gaudard* (Montpellier, France), M. Elhaj, M. Villiet, P. Colson 24th ECCMID / Barcelona Final Programme Posters Dalbavancin for the treatment of complicated skin and soft tissue infections in patients with and without diabetes mellitus in the DISCOVER studies S. Puttagunta* (Branford, CT, United States), M. Dunne 113 Chairs, Speakers & Authors eP409 Exhibition eP408 General Information EPOSTER VIEWING: New and not so new antibiotics ePosters Viewing Stations ePoster Viewing Saturday, 10 May 2014 - Tuesday, 13 May 2014 eP424 Ceftaroline as salvage therapy for MRSA osteoarticular infections S. Parsaei* (Saint Louis, MO, United States), C. Johnson, S. Liang, J. Marschall eP425 The effectiveness and safety with ceftaroline fosamil (CPT) therapy for lower respiratory tract infections (LRTI) in a retrospective multi-centre study A. Casapao* (Detroit, United States), S. Davis, V. Barr, K. Klinker, D. Goff, K. Barber, R. Mynatt, K. Kaye, J. Pogue, M. Rybak eP426 eP427 eP428 eP429 Ceftaroline fosamil for treatment of communityacquired pneumonia as first versus second-line therapy: capture study experience D. Guervil, K. Kaye, A. Hassoun, P. Cole* (Oakland, United States), X. Huang, H.D. Friedland eP434 Concordance between early and late response in ESTABLISH-1 and ESTABLISH-2: pooled results from two phase 3 trials in acute bacterial skin and skin structure infections E. Fang* (San Diego, United States), C. De Anda, A. Das, P. Prokocimer Viewing Stations EPOSTER VIEWING: New and old beta-lactamase inhibitors eP435 Ceftaroline fosamil (CPT-F) in bacteraemia associated with community-acquired pneumonia (CAP) or acute bacterial skin and skin structure infections (ABSSSI) Y. Golan* (Boston, MA, United States), M. Ding, Q. Zhao, A. Jandourek, X. Huang Ceftazidime-avibactam activity tested against select Gram-negative organisms from a global surveillance programme (2011) in relation to the ceftazidime epidemiologic cut-off value R.K. Flamm* (North Liberty, IA, United States), D.J. Farrell, H.S. Sader, R.N. Jones eP436 In vitro activity of ceftazidime-avibactam (CAZ-AVI) and comparators against Gramnegative pathogens isolated from patients in Canadian hospitals in 2009-2012: CANWARD surveillance study P. Lagacé-Wiens* (Winnipeg, Canada), H. Adam, A. Denisuik, J. Karlowsky, A. Walkty, D. Hoban, G.G. Zhanel eP437 Activity of ceftazidime-avibactam and comparators against colistin non-susceptible Enterobacteriaceae and Pseudomonas aeruginosa isolated in 2012: the international network for optimal resistance monitoring (INFORM) study M. Hackel* (Schaumburg, United States), S. Bouchillon, R. Badal, D. Biedenbach, W.W. Nichols eP438 Evaluation of the activity of ceftazidimeavibactam (CAZ-AVI) against fluoroquinolone (FQ)-resistant Enterobacteriaceae and Pseudomonas aeruginosa C. Pitart* (Barcelona, Spain), F. Marco, T.A. Keating, W.W. Nichols, J. Vila Comparison of clinical outcomes with ceftaroline fosamil (CPT-F) in the treatment of methicillinresistant Staphylococcus aureus bacteraemia (MRSAB) S. Arshad* (Detroit, United States), P. Hartman, D. Moreno, M. Perri, M. Zervos Staphylococcus aureus bacteraemia secondary to CSSTI or CAP: capture study experience J. Vazquez, C. Maggiore, D. Guervil, P. Cole* (Oakland, United States), A. Smith, H.D. Friedland eP431 Early clinical response in a randomised controlled phase 3 study of ceftobiprole versus ceftriaxone with or without linezolid in patients with community-acquired pneumonia requiring hospitalisation T. Welte* (Hanover, Germany), G. Herrera, Y.-C. Chuang, A. Demange, M. Engelhardt 114 Estimating the cost-effectiveness of linezolid for the treatment of methicillin-resistant Staphylococcus aureus (MRSA) nosocomial pneumonia in Taiwan B. Wang* (New York, United States), C.H. Fang, W. Furnback, R. Kim, Y.W. Yang Ceftaroline fosamil for treatment of communityacquired pneumonia in the intensive care unit: capture study experience C. Maggiore, J. Vazquez, D. Guervil, K. Kaye, C. Cannon, A. Jandourek* (Oakland, United States), A. Smith, H.D. Friedland eP430 eP432 eP433 Linezolid use in a tertiary care centre: indications, appropriateness of prescriptions, predictive factors for adverse events R. Buzelé* (Tours, France), F. Bastides, X. Pourrat, B. Sautenet, P. Rosset, F. Lagarrigue, L. Bernard 24th ECCMID / Barcelona Final Programme ePoster Viewing eP443 eP444 eP445 eP447 Comparative in vitro activity of ceftolozane/ tazobactam against clinical isolates of Enterobacteriaceae: results of the CENIT multicentre study M. García-Castillo* (Madrid, Spain), M. Tato, G. Bou, J. Calvo, E. Cercenado, P. Egea, M.I. Morosini, R. Cantón eP448 Comparative in vitro activity of ceftolozane/ tazobactam against clinical isolates of Pseudomonas aeruginosa: results of the CENIT multi-centre study M. Tato* (Madrid, Spain), M. García-Castillo, A. Moreno-Bofarull, F. Galán-Sánchez, I. García-García, E. Ruiz de Gopegui, F. Marco, R. Medina, R. Cantón eP449 Ceftolozane/tazobactam activity when tested against Gram-negative bacterial isolates from hospitalised patients with pneumonia in European hospitals (2011-2012) D.J. Farrell* (North Liberty, IA, United States), H.S. Sader, R.K. Flamm, R.N. Jones Efficacy and safety of ceftolozane/tazobactam versus levofloxacin in the treatment of complicated urinary tract infections (CUTI)/ pyelonephritis in hospitalised adults: results from the phase 3 aspect-CUTI trial F. Wagenlehner* (Giessen, Germany), O. Umeh, J. Huntington, D. Cloutier, I. Friedland, J. Steenbergen, G. Yuan, M. Yoon, R. Darouiche eP450 Antimicrobial activity of ceftolozane/tazobactam and comparator agents tested against Pseudomonas aeruginosa isolates from 15 European countries and Israel (2011-2012) D.J. Farrell* (North Liberty, IA, United States), H.S. Sader, M. Castanheira, R.N. Jones Evaluation of the potential for drug-drug interactions between ceftolozane/tazobactam and drugs metabolised by CYP1A2 or CYP3A4 or transported by OAT1 and OAT3 M. Wooley, P. Bernardo, B. Miller, E. Hershberger, G. Krishna* (Lexington, United States) eP451 Characterisation of beta-lactamase inhibition by AAI101, an extended-spectrum beta-lactamase inhibitor P. Nordmann* (Fribourg, Switzerland), D. Girlich, R. Pypstra, S. Shapiro eP452 In vitro activity of AAI 101, a new beta-lactamase inhibitor, combined with beta-lactam antibiotics against a challenge panel of beta-lactamresistant Gram-negative clinical isolates S. Mushtaq* (London, United Kingdom), A. Chaudhry, R. Adkin, N. Woodford, R. Pypstra, S. Shapiro Aztreonam-avibactam (ATM-AVI) – inoculum effect against Gram-negative isolates harbouring ESBLs and/or MBLs R. Singh* (Waltham, MA, United States), S. Patey, R. Giacobbe, M. Tanudra, J. Harris, J. O’Donnell, M. Huband Antimicrobial activity of ceftolozane/tazobactam and comparator agents tested against Enterobacteriaceae isolates from 14 European countries and Israel (2012) D.J. Farrell* (North Liberty, IA, United States), H.S. Sader, M. Castanheira, R.N. Jones Ceftolozane/tazobactam activity against Gramnegative bacteria causing urinary tract infections in European hospitals (2011-2012): a report from an international antimicrobial surveillance programme S. McCurdy* (Lexingtong, MA, United States), P.J. Petersen, J. Steenbergen, D.J. Farrell, M. Bassetti 24th ECCMID / Barcelona Final Programme 115 Posters Comparative in vitro activity of ceftazidime (CAZ) and ceftazidime-avibactam (CAZ-AVI) in a European collection of Pseudomonas aeruginosa from cystic fibrosis (CF) patients H. Chalhoub* (Brussels, Belgium), M. Tunney, S. Elborn, A. Vergison, O. Denis, P. Plésiat, B.C. Kahl, F. Van Bambeke, P.M. Tulkens eP442 Ceftolozane/tazobactam activity against Gramnegative bacteria causing intra-abdominal infections in European hospitals (2011-2012): a report from an international antimicrobial surveillance programme S. McCurdy* (Lexingtong, MA, United States), P.J. Petersen, J. Steenbergen, D.J. Farrell, M. Bassetti Chairs, Speakers & Authors eP440 eP441 eP446 Exhibition In vitro activity of ceftazidime-avibactam and comparators against Gram-negative pathogens in Europe – the international network for optimal resistance monitoring (INFORM) 2012 S. Bouchillon* (Schaumburg, United States), R. Badal, I. Morrissey, D. Hoban, M. Hackel, D. Biedenbach, G. Stone General Information eP439 ePosters Saturday, 10 May 2014 - Tuesday, 13 May 2014 ePoster Viewing Saturday, 10 May 2014 - Tuesday, 13 May 2014 eP453 Efficacy of extended-spectrum beta-lactamase inhibitor AAI 101 combined with beta-lactams in murine models of systemic Gram-negative infection M. Paul-Satyaseela, K. Koppolu, U.P. Senthilkumar, R. Pypstra, S. Shapiro* (St-Louis, France) eP461 A rapid latex agglutination test to distinguish Shigella from Escherichia coli: patching the MALDI-TOF “achilles’ heel” B.M. Willey* (Toronto, Canada), G. Ricci, C. Vermeiren, C. Watt, P. Lo, A.E. Simor, S.M. Poutanen eP454 A phase 1 study of the safety, tolerability, and pharmacokinetics of the beta-lactamase inhibitor RPX7009 in healthy adult subjects D.C. Griffith* (San Diego, CA, United States), J.S. Loutit, E.E. Morgan, S. Durso, M.N. Dudley eP462 Mass spectrometry: a fast and efficient method in respiratory bacterial pathogen identification F. Lopez Fabal* (Madrid, Spain), M. Regodón, J.L. Gómez-Garcés eP463 Mitis-group streptococci id by MALDI-TOF MS using a weighted nearest-neighbour approach T. Maier* (Bremen, Germany), C. Lange, M. Kostrzewa eP464 Evaluation of the rapid detection of ST17 and ST-1 group B streptococci using a microflex MALDI-TOF MS (Bruker) C. Meex* (Liège, Belgium), R. Sacheli, R. Naim, J. Descy, M.P. Hayette, P. Huynen, P. Melin eP465 Usefulness of MALDI-TOF technology for identification of microorganisms belonging to the Staphylococcus intermedius group E. Carretto* (Reggio Emilia, Italy), D. Barbarini, F. Brovarone, C. Zuelli, C. Farina, S. Andreoni, V. Savini eP466 MALDI-TOF mass spectrometry based intraspecies differentiation of Yersinia pestis M. Afanasev* (Irkutsk, Russia), A. Ostyak, G. Vdovichenko, E. Tokmakova, S. Balakhonov eP467 Comparison of a direct colony method versus an extraction method for identification of Rhodococcus spp. and Dietzia spp. with the VITEK® MS MALDI-TOF C. Ruiz de Alegria Puig* (Santander, Spain), L. Pilares, J. Navas, L. Martinez-Martinez eP468 Comparison of MALDI-TOF, NAATS and monoclonal kits to detect Neisseria gonorrhoeae L. Gray, M. Wootton* (Cardiff, United Kingdom), L. Davies, M. Perry, P. Brookes, R.A. Howe eP469 MALDI-TOF MS and FTIR-ATR: different biomolecules and distinct outputs in Acinetobacter baumannii typing C. Santana Sousa, J. Botelho, L. Silva* (Porto, Portugal), F. Grosso, J. Lopes, L. Peixe Viewing Stations EPOSTER VIEWING: MALDI-TOF eP455 eP456 eP457 eP458 eP459 eP460 116 Utility of PCR and electrospray ionization mass spectrometry with different types of clinical specimens D. Gascoyne-Binzi* (Leeds, United Kingdom), J. Sandoe, R. O’Hara, R. Barton, M. Wilcox Comparison of matrix-assisted laser desorption ionization time-of-flight mass spectrometry with pulsed-field gel electrophoresis for cluster analysis J.H. Rim* (Seoul, Korea), Y.S. Lee, Y.J. Park, M.S. Kim, E.S. Park, E.J. Ha, D.E. Yong, S.H. Jeong, K.W. Lee, Y.S. Chong Evaluation of success rate, turnaround time, cost analysis and biohazard waste for bacterial identification by using MALDI-TOF MS M. Ge* (Taoyuan, Taiwan), K. Liu, S. Chang, J. Chia, P. Chang, J. Lu Comparison of two commercially available MALDITOF systems for bacterial and yeast identification in a clinical diagnostic laboratory R. Murphy* (London, United Kingdom), M. Wilks Use of the MALDI-TOF MS analyser in a routine diagnostic microbiology laboratory in a developing country A. Bulane, A.A. Hoosen* (Bloemfontein, South Africa) Mass spectrometry with VITEK® MS: impact of culture media on identification results N. Desserrières, M. Arsac, N. Fanjat, P.J. Cotte-Pattat, C. Arthaud, B. Cellière, V. Girard* (La Balme-les Grottes, France), G. Durand, A. Van Belkum, S. Ghirardi 24th ECCMID / Barcelona Final Programme ePoster Viewing eP472 eP473 eP474 eP475 eP476 eP477 Comparison of the Bruker biotyper and VITEK® MS MALDI-TOF systems for identification of glucose nonfermenting Gram-negative bacilli P. Schreckenberger* (Maywood, United States), K. McKinley, J. Tjhio, K. White, A. Rosenfeld, M. Zilliox, X. Gai, A. Wolfe Comparison of MALDI-TOF MS and AFLP for strain typing of ESBL-producing Escherichia coli isolates collected during an outbreak in a Dutch nursing home J. Veenemans* (Tilburg, The Netherlands), M. Welker, A. Van Belkum, A. Pettersson, C. Verhulst, M. Kluytmans- van den Bergh, J.A.J.W. Kluytmans Suitability of MALDI-TOF MS for the identification of Staphylococcus aureus, and members of the Staphylococcus intermedius group (SIG) complex L. Alcalá* (Zaragoza, Spain), M. Simón, A.I. Lopez-Calleja, C. Ortega, C. Torres, N. Viguera, E. Gómez-Sanz, M.J. Revillo, A. Rezusta Detection of extended-spectrum beta-lactamaseproducing Escherichia coli ST131 and ST405 clonal groups by matrix-assisted laser desorption ionization-time of flight mass spectrometry Y. Matsumura* (Kyoto, Japan), M. Tanaka, Y. Yamamoto, M. Nagao, Y. Ito, S. Takakura, S. Ichiyama Impact of matrix-assisted laser desorption/ ionization-time of flight mass spectrometry on antibiotic optimisation in critically ill patients with Gram-negative pneumonia C.V. Murphy* (Columbus, OH, United States), S.M. Adriance, K.A. Bauer Adenovirus serotype discrimination by matrixassisted laser desorption/ionization time-offlight (MALDI-TOF) mass spectrometry analysis A. Calderaro* (Parma, Italy), M.C. Arcangeletti, I. Rodighiero, M.C. Medici, F. De Conto, C. Chezzi eP479 Evaluation of matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) for accurate and fast identification of yeasts isolated from bloodstream infections N. Karabicak* (Ankara, Turkey), O. Karatuna, I. Akyar eP480 MALDI-TOF mass spectrometry analysis for the differentiation of the pathogenic intestinal amoeba Entamoeba histolytica from the nonpathogenic Entamoeba dispar isolated from biological samples A. Calderaro* (Parma, Italy), M. Piergianni, C. Gorrini, G. Piccolo, M. Buttrini, S. Montecchini, M.C. Medici, M.C. Arcangeletti, C. Chezzi, F. De Conto eP481 Differentiation of vanA-positive E. faecium from vanA-negative E. faecium by matrix-assisted laser desorption ionization-time of flight mass spectrometry S. Nakano* (Kyoto, Japan), Y. Matsumura, T. Noguchi, M. Yamamoto, M. Nagao, Y. Ito, S. Ichiyama eP482 MALDI-TOF MS in Streptococcus agalactiae screening of pregnant women M. Pappné Ábrók* (Szeged, Hungary), Á. Arcson, A. Lázár, E. Urbán, J. Deák eP483 Direct identification of urinary tract pathogens from urine samples using VITEK® MS matrixassisted laser desorption ionization time-of-flight mass spectrometry system K.G. Park* (Seoul, Korea), Y.J. Park, S.H. Shin, J.Y. Chang, Y.S. Kim, K.W. Lee, H.J. Ryu eP484 Rapid identification of Acinetobacter baumannii via matrix-assisted laser desorption ionization time-of-flight and antimicrobial stewardship intervention in patients with pneumonia and/or bacteraemia E. Wenzler* (Hilliard, United States), D.A. Goff, J.E.W. Johnston, K.A. Bauer 24th ECCMID / Barcelona Final Programme 117 Posters MALDI-TOF: a reliable method for the identification of Aeromonas from clinical samples F. Latif-Eugenín* (Reus, Spain), S. Solis del Baño, D. Tena, N.M. Martínez, M. Álvarez, F. García, A. Rezusta, R. Beaz-Hidaldo, M.J. Figueras Characterisation and identification of poliovirus type 1 proteins by matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry A. Calderaro* (Parma, Italy), M.C. Arcangeletti, I. Rodighiero, M.C. Medici, F. De Conto, C. Chezzi Chairs, Speakers & Authors eP471 eP478 Exhibition MALDI-TOF for the identification of Burkholderia cepacia complex from patients with cystic fibrosis C. Lucas, S. Srivastava, W. Mackay, I.M. Gould, G. Ramage, C.L. Williams* (Kilmarnock, United Kingdom) General Information eP470 ePosters Saturday, 10 May 2014 - Tuesday, 13 May 2014 ePoster Viewing Saturday, 10 May 2014 - Tuesday, 13 May 2014 eP485 To MALDI or not to MALDI: specificity of chromogenic agars for identifying Escherichia coli from urine cultures B.M. Willey* (Toronto, Canada), O. Oleung, I. Manji, S. Kim, A. Tsang, E. Ramoutar, S. Tharmaradinam, P. Lo, S.M. Poutanen eP493 Effects of selective digestive decontamination (SDD) on the gut resistome E. Bülow* (Utrecht, The Netherlands), T. Bello Gonzalez, D. Versluis, L. Ogilvie, M.M. D’Andrea, H. Smidt, B.V. Jones, R.J.L. Willems, M. Bonten, W. Van Schaik eP486 Comparison of two commercially available chromogenic agars for the detection of MRSA in a large panel of specimens R. Walker* (Birmingham, United Kingdom), J. Ashby, R. Anderson, P. Patel, H. Kilgariff eP494 Respiratory microbiota of paediatric cystic fibrosis patients using 16S-targeted deep sequencing C. Holmes* (Leicester, United Kingdom), D. Rivett, D. Modha, K. Bruce, E. Gaillard eP495 Study of the digestive flora of 20 Lebanese patients in remission from Crohn’s disease and comparison to healthy subjects G. Rizkallah, R. Sayegh, A. Hajj* (Beyrouth, Lebanon), P.H. Seksik, G. Trugnan, D. Karam Sarkis eP496 Use of the mucosal F. prausnitzii/E.coli index as a marker of microbiota improvement in ulcerativecolitis dysbiosis after treatment with mesalazineMMX (Mezavant™) J. Miquel Cusachs* (Girona, Spain), D. Busquets Casals, M. Serra-Pagès, J. Garcia Gil, X. Aldeguer Manté eP497 Comparisons of the vaginal microbiomes of healthy pregnant women of four ethnic backgrounds, and of Caucasian pregnant women in health and disease G.L. Mendz* (Darlinghurst, Australia), S.J. Lord, N.O. Kaakoush, J.A. Quinlivan Preliminary results on the impact of empirical treatment using colistin-levofloxacin vs. meropenemlevofloxacin in the intestinal microbiome of VAP patients: a randomised clinical trial L. Muñoz* (Barcelona, Spain), I. Roca, J. Nowak, E. Zander, J.M. Cisneros, P. Higgins, H. Seifert, J. Vila eP498 Profile similarities of gut microbiota in allergic and non-allergic children at 5 and 10 years of age T. Drell* (Tartu, Estonia), A. Larionova, J. Simm, K. Heilman, T. Voor, E. Sepp The oral resistome: from metagenomics to antimicrobial resistance of the microbiota in the mouth B.B. Wintermans* (Amsterdam, The Netherlands), C.M.J.E. Vandenbroucke-Grauls, A.E. Budding eP499 Dental root canal microbiota in chronic apical periodontitis patients (data from Illumina sequencing) R. Mändar* (Tartu, Estonia), V. Vengerfeldt, K. Pilka, M. Saag, H. Nõlvak, J.-K. Preem, K. Oopkaup, J. Truu eP500 Molecular identification of bacterial communities associated with caries by denaturing gradient gel electrophoresis fingerprinting approach E. Alia, B. Romero-Hernández* (Madrid, Spain), A.M. Sánchez-Díaz, J.D. Caballero, M. Hernández-García, G. Chinchón, D. Parra-Pecharomán, J. López-Palafox, L. Gil, R. Del Campo Viewing Stations EPOSTER VIEWING: Microbiome and resistance: what are they telling us? eP487 Analysis of vaginal microbiome of women with vaginitis symptoms and comparison with BD Affirm VPIII® identification test K.H. Hong* (Seoul, Korea), S.K. Hong, S.I. Cho, M. Seong, S.S. Park eP488 The vaginal microbiome as a predictor for acquiring Chlamydia trachomatis, a case control study R. Van Houdt* (Amsterdam, The Netherlands), B. Ma, J. Van der Helm, S. Bruisten, H. De vries, J. Ravel eP489 eP490 eP491 eP492 118 Gut microbiota in Mexican obese youth N. Castro* (Chilpancingo, Mexico), R.B. Radilla-Vázquez, B. Illades-Aguiar, E. Flores-Alfaro, I. Parra-Rojas Gut microbiota continues to evolve during the first five years of life A. Eck* (Amsterdam, The Netherlands), N.B.M.M. Rutten, I. Besseling-van der Vaart, G.T. Rijkers, A.M. De Vlieger, P.H.M. Savelkoul, A.E. Budding 24th ECCMID / Barcelona Final Programme ePoster Viewing Saturday, 10 May 2014 - Tuesday, 13 May 2014 Viewing Stations EPOSTER VIEWING: MDR Acinetobacter baumannii eP510 Fitness cost of fluoroquinolone resistance in Acinetobacter baumannii mediated through a combination of gyrA/parC mutations and efflux J. Nowak* (Cologne, Germany), H. Seifert, P.G. Higgins Viewing Stations EPOSTER VIEWING: Antibiotic stewardship programmes Large dissemination of blaOXA-58 and blaOXA-23 carbapenemase genes of Acinetobacter baumannii in a Tunisian neonatal intensive care unit A. Mabrouk, W. Achour* (Tunis, Tunisia), S. Ennigrou, R. Baaboura, A. Ben Hassen eP511 Relevance of microbiological aspects in the results of the first year of a multidisciplinary sepsis unit in a teaching hospital J. Camarena* (Valencia, Spain), R. Gonzalez, B. Bonet, S. Sancho, R. Zaragoza, J.M. Nogueira eP504 Carbapenem resistance molecular determinants in nosocomial isolates of multidrug-resistant Acinetobacter baumannii in Tehran Hospital, Iran A. Karmostaji* (Bandar-Abbas, Iran), S. Najar Peerayeh, P. Davoodian, S. Javadpour eP512 International antimicrobial stewardship pharmacist mentoring programme: united we stand, divided we fall D.A. Goff* (Columbus, United States), K. Bauer, D. Van den Bergh, A. Brink, J. Taljaard, M. Mendelson eP505 First report of ISAba825 upstream of blaOXA-143 gene in carbapenem-resistant Acinetobacter baumannii (ACB) clinical isolates R. Cayô* (São Paulo, Brazil), A.P. Matos, F. Rodrigues-Costa, R. Girardello, C.G. Carvalhaes, A.C. Gales eP513 Results of a stewardship programme for the management of S. aureus bacteraemia J. Boelens* (Ghent, Belgium), I. Leroux-Roels, S. Callens, F. Buyle, D. Vogelaers, On behalf of the Multidisciplinary Infection Team eP514 eP506 OXA-253, a variant of the carbapenemhydrolysing class D beta-lactamase OXA-143 in Acinetobacter baumannii D. Girlich* (Le Kremlin Bicêtre, France), Q. Damaceno, A.C. Oliveira, P. Nordmann eP507 Effect of the acquisition of reduced susceptibility to biocides on the expression of genes encoding porins and efflux pumps in Acinetobacter baumannii F. Fernández-Cuenca* (Seville, Spain), P. Egea, M. Tomás-Carmona, G. Bou, L. Martínez-Martínez, J. Vila, J. Pachón, J.M. Cisneros, J. Rodríguez-Baño, A. Pascual Promoting the appropriateness of antibiotic prescribing and decreasing the parenteral antibiotic prescribing amount by an effective multidimensional antibiotic stewardship programme W. Wang* (Taichung, Taiwan), C. Huang, S. Chou, Y. Huang, S. Chan eP515 Outcome of implementation of antimicrobial review notice stickers and care bundle in a large district general hospital in the east of England T. Vaghela* (Watford, United Kingdom), A. Flatt, S. Parida, R. Wiggins, P. Seetulsingh eP516 Evaluation of active interventions for bloodstream infections in a Japanese university hospital M. Nagao* (Kyoto, Japan), G. Hotta, K. Kato, S. Nakano, T. Yunoki, M. Yamamoto, Y. Matsumura, Y. Ito, S. Takakura, S. Ichiyama eP508 Verification of the amino acid substitutions in adeRS for increasing tigecycline resistance in clinical isolates of the extensively drug resistant Acinetobacter baumannii J.R. Sun* (Taipei, Taiwan), T.S. Chiueh 24th ECCMID / Barcelona Final Programme Posters eP503 ePosters Searching for peritonitis-causing agents in the normal microbiota of peritoneal dialysis patients: analysis of possible routes of infection L. Simões Silva* (Porto, Portugal), S. Ferreira, S. Silva, R. Araujo, M.J. Sousa, C. Santos-Araújo, M. Pestana, I. Soares-Silva, B. Sampaio-Maia AdeR protein regulates AdeABC expression by binding to a direct-repeat motif in the intercistronic spacer T.S. Chiueh* (Taipei, Taiwan), B.J. Huang, T.Y. Chang, J.R. Sun, C.L. Perng 119 Chairs, Speakers & Authors eP502 eP509 Exhibition Human microbiota biobank (HUMB) at University of Tartu, Estonia T. Rööp* (Tartu, Estonia), H. Mändar, M. Mikelsaar, R. Mändar General Information eP501 ePoster Viewing Saturday, 10 May 2014 - Tuesday, 13 May 2014 eP517 The implementation of a national OPAT programme in Ireland S. Clarke* (Dublin, Ireland), N. Curtin, OPAT Working Group eP518 Prospective cross-sectional audit of antibiotic prescriptions in a sample of French general practitioners C. Etienne, C. Pulcini* (Nice, France) eP519 eP520 Antimicrobial stewardship ward-focused approach – the Pennine model Z. Fang* (Oldham, United Kingdom), E. Hughes, S. Shah, A. Stone, I. Cartmill, E. Trautt, H. Panigrahi Antibiotic stewardship programme reduces the usage and costs of systemic antibiotics and lowers in-hospital mortality D.S. Medvedev* (Cherepovets, Russia), N.V. Zakharova eP527 A multi-level antibiotic stewardship intervention leading to huge changes in antibiotic class, however overall antibiotic use remains the same N. Fawcett* (Oxford, United Kingdom), N. Jones, T. Clarke eP528 Physicians’ perception of the factors which impact on successful changes to antibiotic prescribing made at a tertiary centre N. Fawcett* (Oxford, United Kingdom), N. Jones eP529 Reflection over prescribing patterns reduced prescribing rates for antibiotics against respiratory tract infections in western Sweden C. Ahren* (Gothenburg, Sweden), D. Björk, A. Edholm, M. Hess, G. Jacobsson, P.D. Sundvall, P. Ulleryd eP530 Run for the appropriateness: impact of an antimicrobial stewardship programme in a large general teaching hospital M. Giannella* (Bologna, Italy), M. Bartoletti, S. Tedeschi, F. Cristini, M. Morotti, C. Sacripanti, F. Tumietto, F.F. Trapani, C. Puggioli, P. Viale eP531 Escherichia coli isolated from urinary tract infections of Lebanese patients between 2005 and 2012: epidemiology and profiles of resistance Z. Daoud, M.A. Abu Jaoudeh* (Beirut, Lebanon), S. Samad, K. Masry eP521 Attitudes towards antimicrobial stewardship: a challenge for private hospitals in Australia? M. Cotta* (Melbourne, Australia), M. Robertson, M. Tacey, C. Marshall, K. Thursky, D. Liew, K. Buising eP522 Improving in-hospital antimicrobial prescribing by participating with prescribers to develop tailormade intervention bundles J.J. Sikkens* (Amsterdam, The Netherlands), M.H.H. Kramer, E.J.G. Peters, M.A. Van Agtmael eP523 Impact of antimicrobial stewardship programme implementation in medical wards, Saudi Arabian experience A. Malhani* (Riyadh, Saudi Arabia), N. Alghamdi, M. Enani eP532 The analyses of systemic fluoroquinolone use in children under 18 years of age before and after drug utilisation review E. Kim* (Seoul, Korea), J. Shin, W. Kang, S. Hyeon, D. Kim, S. Choi, K.I.M. Yae-Jean eP524 Physicians’ knowledge, perception and attitudes towards antimicrobial prescribing; a cross-sectional study from Saudi Arabia A.M. Albaadani* (Riyadh, Saudi Arabia), W.A. Alfahadl, K. Baig, A.S. Omrani eP533 eP525 Monthly prescriber-led antimicrobial stewardship audits in a 900-bed tertiary and quaternary care teaching hospital – an intervention to improve compliance with good prescribing practice A. Fife* (London, United Kingdom), N. Desai, M. Talpaert, P. Donohoe Increasing the knowledge and awareness of antibiotics in Stockholm county by introducing internet-based education tools for prescribers and the public A. Hahlin* (Stockholm, Sweden), S. Hellman, E. Titelman, M. Vading, C. Falk, A. Lundevall eP534 Can a mass media campaign affect antibiotic use in a region with both a low rate of antibiotic prescribing and low rate of antibiotic resistance? G. Jacobsson* (Gothenburg, Sweden), D. Björk, A. Edholm, M. Hess, P.-D. Sundvall, P. Ulleryd, C. Ahrén, E. Lampi, F. Carlsson eP526 120 An antimicrobial stewardship programme improves clinical outcomes in surgical wards R. Güerri Fernandez* (Barcelona, Spain), J. Villar-García, M.L. Sorli Redo, J. Fernandez Morato, A. Domínguez Gonzalez, M. Trenchs, A. Diez Perez, S. Grau Cerrato, J.P. Horcajada Gallego 24th ECCMID / Barcelona Final Programme ePoster Viewing Saturday, 10 May 2014 - Tuesday, 13 May 2014 eP538 Mobile device applications for antimicrobial stewardship – is there a role in primary care? Preliminary findings from a survey of general practitioners in the United Kingdom M. Mcleod, E. Charani* (London, United Kingdom), E. Castro-sanchez, L.S.P. Moore, M. Gharbi, M. Gilchrist, A. Holmes eP539 Usage statistics of individually designed optimum dosing strategies, a multi-model-based online application to individualise antibiotic dosing in critically ill patients A. Farkas, G. Daroczi, J. Roberts* (Queensland, Australia) eP540 Antifungal drug interactions database and apps for iPhone and Android G.T. Atherton* (Manchester, United Kingdom), S. Banfield, J. Bartholomew, D.W. Denning eP541 Determinants of the successful adoption of a computerised antimicrobial stewardship programme at a university teaching hospital S. Zaidi* (Hobart, Australia) eP542 Development of national antimicrobial prescribing and stewardship competences D.A. Ashiru-Oredope* (London, United Kingdom), B. Cookson, C. Fry eP543 Antimicrobial stewardship: does it really work? Yes it does! D. Nayar* (Durham, United Kingdom), S. Brown, D. Allison, C. Aldridge, L. Lim, J. Sloss, C. Grey, M. Wright, P. Gordon, A. Foden eP544 Serotype distribution and antimicrobial susceptibility of Streptococcus pneumoniae causing peritonitis M. Alonso, J.M. Marimon Ortiz de Zarate* (San Sebastian, Spain), C. Zugazaga, M. Ercibengoa, E. Pérez-Trallero eP545 Study of clinical presentation, serotype distribution, vaccination history and outcome of pneumococcal bacteraemia in Milton Keynes, UK A. Jarzynska* (Milton Keynes, United Kingdom), L. Brako, M. Healy, R. Randhawa, M.M. Raza eP546 Invasive pneumococcal disease in Poland, 2011-2012 A. Skoczynska* (Warsaw, Poland), A. Kuch, I. Wasko, M. Markowska, P. Ronkiewicz, B. Matynia, W. Hryniewicz eP547 Characteristics of invasive pneumococcal disease in immunocompromised adults after PCV7 implementation, Toronto, Canada, 2005-2011 A. Shigayeva* (Toronto, Canada), A. McGeer, W. Rudnick, K. Green, A. Plevneshi, S. Pong-Porter, D.E. Low eP548 Risk factors for adverse outcome in adult patients with invasive pneumococcal disease M. Trojanek* (Prague, Czech Republic), K. Herrmannova, O. Dzupova, Z. Blechova, S. Arientova, A. Gabrielova, J. Kozakova, J. Motlova, H. Zemlickova, V. Maresova eP549 The burden of pneumococcal pneumonia among older adults in southern Catalonia, Spain X. Raga* (Tarragona, Spain), X. Clivillé, S. Noguer, Á. Vila, O. Ochoa, R. Reig, C. De Diego, M. Mas, S. Hernández eP550 Current epidemiology and burden of pneumococcal diseases in elderly population in the republic of Korea: a prospective, multi-centre, observational study M.J. Kim* (Seoul, Korea), S.Y. Kee, S.H. Paik, Y.H. Choi, I. Bae, S.Y. Kim, Y.K. Kim, J.A. Hur, Y.M. Jo, J.Y. Song 24th ECCMID / Barcelona Final Programme 121 ePosters Global online internet antimicrobial stewardship training programmes D. Goff* (Columbus, United States), J. Bosso, M. Rybak EPOSTER VIEWING: Streptococcus pneumoniae Posters eP537 Viewing Stations Chairs, Speakers & Authors Taking antimicrobial stewardship initiatives to the next level: development of a serious prescribing game for acute care E. Castro Sanchez* (London, United Kingdom), E. Charani, L.S.P. Moore, M. Gharbi, A.H. Holmes Exhibition eP536 Establishing a futuristic model of communitybased outpatient parenteral antibiotic therapy service with a balance of commissioning elements: an acute-commissioner-primary care transformational project in north-west England A. Guleri* (Blackpool, United Kingdom), R. Sharma, S. Rourke General Information eP535 ePoster Viewing Saturday, 10 May 2014 - Tuesday, 13 May 2014 eP551 eP552 eP553 Low prevalence of Streptococcus pneumoniae respiratory infection among Malaysian Hajj pilgrims in 2013 H. Hasan, N. Ismail* (Kelantan, Malaysia), Z. Abdul Rahman, Z. Mohamed, S. Md Noor, R. Abd. Rahman, N. Naing, A. Abd. Aziz, N. Zainuddin, A. Harun Bacteraemic pneumococcal pneumonia in chronic obstructive pulmonary disease patients in the 13-valent conjugate vaccine era A. Sangil* (Barcelona, Spain), M. Andrés, E. Espejo, M. Riera, M. Xercavins, J. Pérez, M. Rodríguez-Carballeira, J. Garau, E. Calbo Epidemiology of invasive pneumococcal disease in immunosupressed adults in a setting with a slow progression in children conjugate vaccine uptake. A. Sangil* (Barcelona, Spain), M. Andrés, E. Espejo, M. Xercavins, M. Riera, M. Rodríguez-Carballeira, J. Pérez, J. Garau, E. Calbo Viewing Stations eP559 Prevalence of Chlamydia trachomatis in asymptomatic women in Algiers centre, Algeria H. Ziane* (Algiers, Algeria), S. Gourari, H. Djaballah, M. Boufekkane, S. Arib, I. Boubekri, M. Souici, Z. Sadi, M. Tazir eP560 Prevalence study of Chlamydia trachomatis in a tertiary hospital (2009-2013). Potential role in reactive arthritis R. Bretones-Miguélez, B. Pino-Calm, C. Grillo Grillo* (Santa Cruz de Tenerife, Spain), J. Alcoba-Flórez eP561 Genital Chlamydia trachomatis testing and care in general practice in UK, France, Sweden and Estonia A. Uusküla, E. Ricketts, R. Kalda, A. Tisler-Sala* (Tartu, Estonia), H. Fredlund, J. Hedlund, B. Dunais, B. Touboul, C. McNulty eP562 Demonstration of earlier detection of Salmonella species from stool samples by using chromogenic media E. Marrs, A. Jones, S. Cummings, J. Perry* (Newcastle-upon-Tyne, United Kingdom) eP563 Prevalence of Chlamydia trachomatis in symptomatic patients: results from 2001 to 2013 of Ege university hospital C. Cicek, H. Kalfaoglu* (Izmir, Turkey), M. Yalaz, O. Nazli, G. Gundem eP564 Prevalence and predictors of lymphogranuloma venereum in a high-risk population in Italy A. Marangoni* (Bologna, Italy), C. Foschi, A. D’Antuono, M. Compri, P. Nardini, S. Bellavista, N. Banzola, A. Filippini, R. Cevenini eP565 Lymphogranuloma venereum in Switzerland, 2008-2013 D. Goldenberger* (Basel, Switzerland), R. Frei, F. Dutly eP566 Prevalence and risk factors associated with Mycoplasma genitalium infection in a South African women cohort J.-H. Dubbink, B. Hay, S. Ouburg, C. Le Roy, S. Pereyre, S.A. Morré, C. Bebear* (Bordeaux, France), R.H. Peters eP567 Y chromosome DNA presence in cervicovaginal self-collected samples: implications for epitheliotropic sexually transmitted infections prevalence J. Silva* (Porto, Portugal), F. Cerqueira, R. Medeiros EPOSTER VIEWING: STD and other genital infections eP554 eP555 eP557 eP558 122 Self-collected vaginal lavage for detection of human papillomavirus, bacterial vaginosis, Chlamydia trachomatis, and other vaginal pathogens in young women in Germany Y. Deleré* (Berlin, Germany), M. Fesenfeld, C. Remschmidt, A.M. Kaufmann, J. Leuschner, O. Wichmann, M. Pawlita, M. Schmitt Optimisation of the diagnostic strategy for detecting C. trachomatis as a cause of female infectious infertility K. Gillmann, M.K. Bohlmann, R. Speer, H. Mark, S. Graspeuntner, A. Schultze- Mosgau, R. Lettau, G. Griesinger, I. König, J. Rupp* (Lübeck, Germany) Diagnosis of extra-genital Chlamydia and/or Neisseria gonorrhoeae infections by VERSANT® CT/GC DNA 1.0 assay A. Marangoni* (Bologna, Italy), C. Foschi, P. Nardini, A. D’Antuono, M. Compri, F. Macca, A. Kintrili, N. Banzola, A. Filippini, R. Cevenini Prevalence of Chlamydia trachomatis infection in the general population of women in Qatar A. Athani* (Doha, Qatar), L. Abu-Raddad, H. Abdul-Rahim 24th ECCMID / Barcelona Final Programme ePoster Viewing Saturday, 10 May 2014 - Tuesday, 13 May 2014 eP568 Prevalence of sexually transmitted diseases among Italian prison inmates in 2012: the experience of ‘Casa Circondariale di Modena’ A. Bedini* (Modena, Italy), E. Garlassi, C. Stentarelli, G. Federzoni, S. Petrella, G. Filiberti, V. Hagbe, S. Lucanto, A.M. Pezzi, C. Mussini eP577 Ureaplasma species and antimicrobial susceptibility in asymptomatic women in northern Greece T.Z. Kotrotsiou, M. Exindari, E. Diza, G. Gioula, A. Melidou, K. Kaplanis, N. Malisiovas* (Malisiovas, Greece) eP569 Prevalence of high-risk HPV infection in female sex workers in Spain X. Camino Ortiz de Barron* (San Sebastian, Spain), M.A. Von Wichmann de Miguel, H. Azkune Galparsoro, M.J. Bustinduy, I. Sanz Bereciartu, G. Cilla eP578 Infection with Chlamydia trachomatis in infertile women in Poland I. Chudzicka-Strugala* (Poznan, Poland), T.M. Karpinski, A. Zeidler, B. Banaszewska, L. Pawelczyk, A. Szkaradkiewicz eP570 High prevalence of HIV infection in homo/bisexual men with other sexually transmitted diseases R. Del Romero* (Madrid, Spain), B. Menéndez, T. Puerta, J. Balllesteros, P. Clavo, M. Vera, M. Raposo, V. Paredes, C. Rodríguez, I. Río A new real-time multiplex polymerase chain reaction for the detection of Treponema pallidum, herpes simplex-1/2 and Haemophilus ducreyi in genital, anal and oropharyngeal ulcers M. Glatz, N. Juricevic, M. Altwegg, S. Bruisten, P. Komericki, S. Lautenschlager, R. Weber, P. Bosshard* (Zurich, Switzerland) eP574 eP575 eP576 Epidemiology of genital herpes virus type 1 and 2 infections F. Sidoti* (Turin, Italy), C. Balloco, A. Curtoni, M. Rittà, E. Piasentin, G. Bianco, C. Costa, R. Cavallo Prevalence of aerobic vaginitis among different age groups of symptomatic patients S. Baka, I. Tsirmpa* (Athens, Greece), E. Saltaoura, A. Chasiakou, S. Hassiakou, V. Gennimata, E. Kouskouni Global prevalence of recurrent vulvovaginal candidiasis D.W. Denning, M. Kneale, R. Rautemaa-Richardson* (Manchester, United Kingdom), J.D. Sobel eP580 Malaria in Istanbul: the epidemiological, laboratory, clinical and therapeutic features of 63 cases A. Inan* (Istanbul, Turkey), S.C. Ozyurek, S. Bolukcu, S.S. Akcay, C. Kuyumcu Akalan, E. Karagul eP581 Successful treatment of Plasmodium falciparum malaria recrudescence with the same drug despite previous treatment failure S. Senbayrak Akcay, S. Ozyurek, A. Inan* (Istanbul, Turkey), C. Akalan Kuyumcu, O. Barkay, S. Erol eP582 Delayed haemolysis after parenteral artesunate therapy for severe malaria in a returning Canadian traveller M. Charles* (Edmonton, Canada), L. Asadi, J. Pattterson, S. Houston eP583 False-positive patterns of malaria rapid diagnostic tests in patients with rheumatoid factor J. Lee, J. Jang, C. Cho, C. Lim* (Seoul, Korea) eP584 Malaria in travellers. Diagnostic approach in a European health unit M. Pessanha* (Lisbon, Portugal), T. BaptistaFernandes, T. Morais, J. Viana, R. Rodrigues, T. Marques 24th ECCMID / Barcelona Final Programme ePosters eP573 Staining property of roselle plant (Hibiscus sabdariffa) on Plasmodium species and on blood cells in malaria endemic country M. Alo* (Abakaliki, Nigeria), U. Ugah Posters High rates of sexually transmitted infections in HIV-infected individuals attending an STD clinic in the US J. Castro* (Miami, United States), M. Alcaide eP579 Chairs, Speakers & Authors eP572 EPOSTER VIEWING: Malaria Exhibition Incidence of other sexually transmitted infections in patients diagnosed with HIV infection M. Chamón, R. Pérez, M. Vera, I. Río, V. Paredes, I. Calzas, M. Grau, M. Villa, C. Rodríguez, J. Del Romero* (Madrid, Spain) Viewing Stations 123 General Information eP571 ePoster Viewing Saturday, 10 May 2014 - Tuesday, 13 May 2014 eP585 An eleven-year epidemiological study report of malaria in Adana, Turkey F. Kuscu* (Adana, Turkey), D.B. Ozturk, S. Gul, M.L. Babayigit eP586 Antibody responses of Greeks and immigrants residing in areas of local malaria transmission in Greece M. Mavrouli* (Athens, Greece), E.T. Piperaki, C. Hadjichristidoulou, A. Tsakris eP588 eP589 eP590 Performance of real-time PCR in the diagnosis of imported malaria: comparison with microscopy and RDT, and impact on submicroscopic malaria P. Trevisi* (Madrid, Spain), M. Subirats, N. Iglesias, B. López-Quintana, G. Ramírez, S. Puente, C. Toro Evaluation of malaria species in Haiti: detection of sub-clinical infection T.M. Zervos* (Detroit, United States), T. Prentiss, S. Arshad, K. Prentiss, J.M. Zervos, K. Wilt, S. Bruni, J. Sime, M.A.B. Lucien, M.J. Zervos Characterisation of the commercially available fluorescent chloroquine-BODIPY conjugate, LynxTag-CQ™ green, as a marker for chloroquine resistance and uptake C.C.Y. Loh, R. Suwanarusk, K.W.K. Chan, Y.Q. Lee* (Singapore, Singapore), L. Rénia, B.M. Russell, L.M.-C. Chow, M.J. Lear, F.H. Nosten, K.S.W. Tan Treatment and risk factors for infections due to polymyxin-resistant Enterobacteriaceae in a university hospital in Londrina, PR, Brazil C.M.D.M. Carrilho* (Londrina, Brazil), C.M.C. Grion, M. Pelisson, M.R.E. Perugini, J.C. Pascual-Garcia, J.S. Perozin, L. Oliveira, J. Gaudereto, M.R. Urbano, S.F. Costa eP595 Carbapenemase-producing bacteria in travellers constitute a potential threat for current hospital infection control programmes R.H.T. Nijhuis* (Velp, The Netherlands), P.H.M. Savelkoul, A.A. Van Zwet eP596 Medical tourism as a source for multidrugresistant pathogens – a cohort analysis M.J. Cohen, R. Nir-Paz, C. Schwartz, I. Gross, N. Minster, A.E. Moses, S. Benenson* (Jerusalem, Israel) eP597 A single-day, point-prevalence study of carbapenemase-producing Enterobacteriaceae (CPE) faecal carriers in long-term care hospitals in Madrid (Spain) depicts a complex clonal and polyclonal dissemination of CPE L. Beatobe, P. Ruiz-Garbajosa* (Madrid, Spain), M. Tato, I. Méndez, M. Gil, L. Aranzábal, S. Alonso, L. García-Picazo, M.A. Lópaz, R. Cantón eP598 Efflux pump genes and chlorhexidine resistance; a clue for Klebsiella pneumoniae infections in intensive care units, Ismailia, Egypt R. Kishk* (Ismailia, Egypt), M. Mandour, W. Hessam, N. Nemr eP599 CTX-M group 1-ESBL producing Klebsiella pneumoniae intra- and extra-hospital clonal dissemination in the north of Portugal D. Gonçalves* (Porto, Portugal), P. Cecílio, C. Iglésias, A. Faustino, A. Estrada, H. Ferreira eP600 Duration of colonisation with ST131 versus other extended-spectrum beta-lactamase (ESBL)producing Escherichia coli: outbreak in a longterm care facility (LTCF) I. Overdevest* (Tilburg, The Netherlands), J. Veenemans, Y. Hendriks, A. Mulders, W. Couprie, J. Johnson, J. Kluytmans eP601 Matrix-assisted laser desorption/ionization timeof-flight mass-spectrometry (MALDI-TOF MS) based typing of ESBL Escherichia coli during a hospital outbreak A. Egli* (Basel, Switzerland), S. Tschudin-Sutter, D. Goldenberger, A. Widmer, R. Frei Viewing Stations EPOSTER VIEWING: MDR Enterobacteriaceae – a major threat eP592 Carbapenemase-producing Enterobacteriaceae in Austria 2010 to 2013 R. Hartl* (Linz, Austria), S. Widhalm, H. Kerschner, P. Apfalter eP593 Carbapenemase-producing Enterobacteriaceae in Spain: results from a national multi-centre study, 2013 J. Oteo, C. Conejo, M. Fernández-Martínez, J. González-López, L. Martínez-García, M. Merino, E. Miró* (Barcelona, Spain), G. Ruíz, L. Zamorano, Spanish collaborating group for the study of carbapenemase-producing Enterobacteriaceae 124 eP594 24th ECCMID / Barcelona Final Programme ePoster Viewing eP604 eP605 Persistence of related blaIMP-4 metallo-betalactamase-producing Enterobacteriaceae from clinical and environmental specimens within a burns unit in Australia – a six-year retrospective study G.H.Y. Leung* (Concord, Australia), T.J. Gray, E.Y.L. Cheong, P. Haertsch, T. Gottlieb Risk factors for acquisition and effect on mortality of carbapenem-resistant K. pneumonia: a case-control study C. Bulut* (Ankara, Turkey), C. Ataman Hatipoglu, K. Arslan, G. Tuncer Ertem, A. Adiloglu, A.P. Demiröz eP606 The epidemiology of carbapenem-resistant Klebsiella pneumoniae stratified by multi-locus sequence typing S. Dhar, E.M. Martin, J.P. McRoberts, K. Hayakawa, T. Lazarovitch, R. Zaidenstein, F. Perez, R.A. Bonomo, K.S. Kaye, D. Marchaim* (Zerifin, Israel) eP607 KPC-producing Klebsiella pneumoniae resistant to tigecycline: epidemiology and risk factors for colonisation during intensive care unit stay M. Papadimitriou Olivgeris* (Patras, Greece), C. Bartzavali, F. Fligou, C. Sklavou, S. Vamvakopoulou, M. Christofidou, K. Filos, M. Marangos, E. Anastassiou eP608 Which patients develop bloodstream infection due to KPC-producing Klebsiella pneumoniae within two days of rectal colonisation? M. Papadimitriou Olivgeris* (Patras, Greece), C. Bartzavali, F. Fligou, S. Vamvakopoulou, C. Sklavou, E. Anastassiou, K. Filos, M. Christofidou, M. Marangos eP610 KPC-producing Enterobacter aerogenes infection F. Tuon, C. Scharf, J. Rocha, J. Cieslinsk, G. Becker, L. Arend, P. Arruda* (Ponta Grossa, Brazil) eP611 Surveillance and molecular epidemiology of KPCproducing Klebsiella pneumoniae strains from an intensive care unit P. Marone* (Pavia, Italy), M. Corbella, A. Piralla, R. Migliavacca, M. Brandolini, M. Spalla, D. Barbarini, G. Ottonello, A. Piazza, L. Pagani eP612 Copper-resistance in Enterobacteriaceae and other proteobacteria from childrens’ intestines A. Sánchez-Valenzuela* (Madrid, Spain), E. Morales, M. Rodríguez, M.J. López-Espinosa, M.T. Coque, J. Sunyer, F. Baquero eP613 A bundle of interventions to reduce colonisation and infection with extensively drug-resistant microorganisms (XDR): focus on carbapenemresistant Klebsiella pneumoniae (CRKP) L. Galani, K. Ioannidis, I. Karaiskos* (Athens, Greece), F. Dasiras, M. Pitsoli, G. Plakias, C. Safiolea, I. Apostolakis, H. Paskalis, H. Giamarellou Posters Microbiological surveillance in a hospitalwide outbreak of OXA-48 producing Enterobacteriaceae. Where should the net be thrown? J.R. Pano-Pardo* (Zaragoza, Spain), J. García-Rodríguez, J. Mingorance, A. Sánchez-Purificación, J. Astray, R. Herruzo, P. Elola, V. Pérez-Blanco, G. Ruiz-Carrascoso Carbapenem-resistant Klebsiella pneumoniae bloodstream infections in intensive care unit – mortality and related predictors in a teaching hospital in Italy D.R. Giacobbe, V. Del Bono* (Varazze, Italy), S. Scabini, C. Saffioti, A. Parisini, A. Molin, G. Buscaglia, A. Gratarola, P. Pelosi, C. Viscoli Chairs, Speakers & Authors eP603 eP609 Exhibition How long to screen for carbapenemase producing Enterobacteriaceae? Time from exposure to detection during a Vim-4 outbreak D. Harvey* (Merseyside, United Kingdom), A. Ledgerton 24th ECCMID / Barcelona Final Programme 125 General Information eP602 ePosters Saturday, 10 May 2014 - Tuesday, 13 May 2014 ISSN: 2052-2975 NMNI New MIcrobes aNd New INfectIoNs New Microbes aNd New iNfectioNs Editor-in-Chief: Michel Drancourt ISSN: 2052-2975 NMNI is an Open Access journal with a focus on new genomes, new microbes, and new technology applied to the diagnosis of infectious and tropical diseases. 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Follow us on twitter: @WB_InfDisease 14-64783 For full details, see www.newmicrobes.com Poster Sessions Antifungal activity of myriocin, a sphingolipid metabolism inhibitor, on fungal biofilms: a preliminary study D. Cirasola, F. Perdoni, M. Biggiogera, P. Signorelli, G. Morace, E. Borghi* (Milan, Italy) P0008 Direct effects of tacrolimus and cyclosporine on Candida albicans M. Erdogan, A. Kalkanci, A. Fouad, E. Senol* (Ankara, Turkey), G. Sucak Turkoz, S. Kustimur P0009 Anti-candidal activity of 18-beta glycyrrhetinic acid and hyaluronic acid M. Stevan* (Vicenza, Italy), E. Fusato, D. Armanini, G. Bertoloni, M. Rassu P0010 In vivo efficacy of a JAK1/2 inhibitor in a murine model of haematogenously disseminated candidiasis J. Meletiadis* (Athens, Greece), A. Elefanti, N. Siafakas, L. Zerva, G. Dimitriadis, P. Tsirigotis P0011 Central nervous system fungal infections and CARD9 deficiency F. Lanternier* (Paris, France), D. Mansouri, A.-S. Bruneel, A. Angoulevant, M.E. Bougnoux, H. Chaussade, O. Lortholary, J.L. Casanova, C. Picard, A. Puel P0012 Production of biofilm by Candida and non-Candida spp. isolates causing fungaemia: comparison of biomass production and metabolic activity and development of a cut-off L. Marcos-Zambrano, P. Escribano, E. Bouza, J. Guinea Ortega* (Madrid, Spain) P0013 Comparative stability analysis of two commercial amphotericin B formulations: liposomal (AmBisome) and lipid complex (abelcet) M.A. Parra* (Madrid, Spain), J.R. Azanza, B. Sádaba P0014 The influence of thymol on C. albicans isolates adhesion – the key stage in biofilm formation J. Szymanska* (Lublin, Poland), A. Kaminska, A. Malm P0015 The role of Candida albicans antigen in atopic dermatitis E. Kasumagic-Halilovic* (Sarajevo, Bosnia and Herzegovina), N. Ovcina-Kurtovic, S. Samardic, S. Omic P0016 Identification and extracellular enzyme activity of opportunistic human pathogenic bipolaris species K. Krizsan* (Szeged, Hungary), A. Lengyel, M. Czikora, C.S. Vágvölgyi, T. Papp POSTER SESSION I: Diagnosis of fungal infections P0001 P0002 P0003 P0004 P0005 Ten-year retrospective case series of patients with galactomannan antigenaemia: implications on the use of serum galactomannan antigen in the diagnosis of invasive and non-invasive aspergillosis J.F.W. Chan* (Hong Kong, China), S.K.P. Lau, S.C.Y. Wong, K.K.W. To, V.C.C. Cheng, K.Y. Yuen, P.C.Y. Woo The value of different mycological methods in the diagnosis of invasive pulmonary aspergillosis A. Gracheva* (Moscow, Russia), V. Okhmat, I. Frolova, G. Klyasova Mupirocin disk diffusion technique for presumptive identification of Pythium insidiosum J. Tondolo* (Santa Maria, Brazil), S. Itaqui, E. Loreto, S. Alves, J. Santurio MALDI-TOF MS as a rapid screening method for azole-resistance in Aspergillus fumigatus E. Vermeulen* (Leuven, Belgium), J. Maertens, K. Lagrou Cost and cost-effectiveness analysis of mass spectrometry (MALDI-TOF MS) identification of Candida spp. from candidaemia at species level E. Gomez G. de la Pedrosa* (Madrid, Spain), R. Canton 15:30 – 16:30 Poster Area POSTER SESSION I: News from the fungal frontier P0005a P0006 Incidence of mixed invasive aspergillosis in a general hospital in Madrid: an underestimated entity? T. Pelaez Garcia* (Madrid, Spain), B. Gama, V. García-Gil, L. Alcazar-Fuoli, P. Escribano, J. Guinea, P. Muñoz, E. Mellado, E. Bouza Combined effect of ozonous oleic acid and terbinafine on Candida albicans S. Gramatiuk* (Kharkov, Ukraine), E. Kochneva, V. Minukhin, O. Jafarli 24th ECCMID / Barcelona Final Programme Chairs, Speakers & Authors P0007 Exhibition Poster Area 127 General Information 15:30 – 16:30 Posters Saturday, 10 May 2014 Poster Sessions Saturday, 10 May 2014 P0017 Phenotypic, genotypic and antifungal susceptibility characterisation of clinical isolates of Exophiala spp. from the stock culture collection of Laboratório Especial de Micologia (LEMI), EPM/UNIFESP W. Colalto, S. Goncalves, D.W.C.L. Santos, A.L. Colombo, A.S.A. Melo* (São Paulo, Brazil) P0018 Characterisation and pathogenicity of Exophiala dermatitidis strains from various sources M. Olsowski* (Essen, Germany), P. Vidigal, J. Buer, P.-M. Rath, J. Steinmann P0019 Eumycetoma and plant-based pharmacotherapy candidates H.E. Hassan* (Medani, Sudan), E.M. Ahmed, H.A. Fahal, W. Sande, A.H. Mohamedani P0020 Role of RTA3 in fluconazole resistance in Candida albicans S.G. Whaley* (Memphis, United States), S. Tsao, K. Barker, M. Raymond, P.D. Rogers P0021 Mutant prevention concentration (MPC) and mutant selection window (MSW) of fluconazole and amphotericin B in Candida albicans and Candida glabrata candidaemia M.A. Bordallo Cardona* (Madrid, Spain), E. Gómez G. de la Pedrosa, R. Cantón Moreno P0022 17-beta-estradiol increases rhodamine 6G efflux in Candida albicans detected by flow cytometric analysis H.C. Xu, X.P. Liu* (Shenzhen, China), S.R. Fan, L.P. Nie P0023 Synergistic effects of diphenyl diselenide and amphotericin B in Trichosporon asahii isolates D. Alves Nunes Mario* (Rio Grande do Sul, Brazil), T. Felli Kubiça, P. Orlandi Barth, E. Silva de Loreto, C. Nogueira, L. Bedin Denardi, S. Hartz Alves P0024 P0025 128 Ultra deep pyrosequencing of Pneumocystis jirovecii reveals higher diversity than previously stated A. Alanio* (Paris, France), J. Menotti, S. Mercier-Delarue, S. Bretagne Inhibition of adhesion of Paracoccidioides spp. by 4 selected peptides identified using phage display technology H.C. Oliveira* (Araraquara, Brazil), J. Michaloski, J.F. Da Silva, L. Scorzoni, A.C.A. De Paula e Silva, D.S. Yamazaki, A.M. Fusco-Almeida, R.J. Giordano, M.J.S. Mendes-Giannini 24th ECCMID / Barcelona Final Programme P0026 Acidosis promotes Rhizopus oryzae-induced endothelial cell injury in vitro via overexpression of host GRP78 receptor and fungal CotH3 T. Gebremariam, J. Edwards Jr., S.G. Filler, A.S. Ibrahim* (Torrance, CA, United States) P0027 14-3-3 gene silencing of Paracoccidioides brasiliensis using antisense RNA C.M. Marcos, J.F. Da Silva, H.C. Oliveira, P.A. Assato, O. Hernández, J.G. McEwen, M.J.S. Mendes-Giannini, A.M. Fusco-Almeida* (Araraquara, Brazil) P0028 Impedance and toxin release studies of bacterial biofilms developed in continuous flow conditions O. Estrada-Leypón* (Barcelona, Spain), V. Ramos, S. Borrós, A.T. Jenkins, A. Moya, G. Gabriel, J. Aguiló, R. Villa 15:30 – 16:30 Poster Area POSTER SESSION I: How to improve fungal diagnosis P0029 Introduction and evaluation of the ‘Candida score’ for adult critical care patients: a prospective, observational pilot cohort study R. Patel* (Dartford, United Kingdom), M. Gilchrist, A. Gonzalez-Ruiz P0030 Characterisation of patients on anidulafungin and evaluation of ‘Candida score’ in critically ill patients on an intensive care unit in a large district general hospital T. Vaghela* (Watford, United Kingdom), A. Flatt, P. Seetulsingh, V. Page, T. Stambach, S. Parida P0031 Does the use of predictive scores really guide the early initiation of antifungal therapy in patients admitted to the ICU for peritonitis? T. Geffriaud* (Lyon, France), A. Gregoire, J. Prothet, B. Devigne, C. Ber, J. Crozon-Clauzel, B. Allaouchiche, T. Rimmelé P0032 An audit of ophthalmological examination of patients with candidaemia; is fundoscopy performed at the correct time? S. Venturelli* (London, United Kingdom), P.A. Riley P0033 Candida colonisation of the lower respiratory tract investigated by conventional culture and fungal microbiome analysis R. Krause* (Graz, Austria), B. Halwachs, I. Klymiuk, G. Gorkiewicz, I. Zollner-Schwetz, T. Valentin, M. Hönigl, G. Thallinger Poster Sessions Saturday, 10 May 2014 P0036 P0037 P0038 P0039 P0040 P0041 P0042 Candida bloodstream infections caused by a novel species Candida quercitrusa: epidemiologically linked infection suggestive of an outbreak with mycological characteristics M. Xiao* (Peking, China), H. Wang, J. Lu, S. Chen, F. Kong, X. Ma, Y. Xu Contribution of 1,3-beta-D-glucan (BDG) to the diagnosis of invasive candidiasis after liver transplantation S. El Anbassi, E. Levesque, E. Sitterle, F. Foulet, J.C. Merle, F. Botterel* (Le Perreux sur Marne, France) Beta-D-glucan for guidance of antifungal therapy at the ICU: a retrospective evaluation in a real life setting: a cohort study J. Wagner, J. Prattes, R.B. Raggam, I. Zollner-Schwetz, T. Valentin, K. Seeber, F. Prueller, S. Fruhwald, R. Krause, M. Hoenigl* (Graz, Austria) Initial (1,3)-beta-D-glucan as a prognostic marker of mortality in Candida spp. bloodstream infections in a teaching hospital in Italy D.R. Giacobbe, V. Del Bono* (Varazze, Italy), A. Mesini, S. Grignolo, P. Tatarelli, F. Artom, A. Parisini, E. Furfaro, F. Miletich, C. Viscoli IL17A, IL22 and kynurenins in patients with candidaemia and healthy controls R. Krause* (Graz, Austria), M. Hönigl, T. Valentin, J. Prattes, J. Wagner, B. Rinner, F. Quehenberger, R. Raggam, A. Meinitzer, I. Zollner-Schwetz Predictors of candidaemia caused by Candida isolates with decreased susceptibility to fluconazole (MIC >= 4 mg/l) M. Puig-Asensio* (Barcelona, Spain), M. Salavert, F. González-Romo, J. Guinea, O. Zaragoza, B. Almirante Should we perform lumbar punctures in every patient with cryptococcosis? S.H. Huang* (Taipei, Taiwan), H.Y. Sun, C.C. Hung, Y.C. Chen, S.C. Chang P0044 Real-time PCR for pneumocystosis diagnosis in non-HIV patients A.L. Bienvenu* (Lyon, France), M. Bouchrik, C. Bossard, M. Wallon, S. Picot P0045 High prevalence of Pneumocystis jirovecii in bronchoalveolar lavage (BAL) samples using a multiplex-nested PCR L. Martinez-Lamas* (Pontevedra, Spain), M. Álvarez-Fernández, M.P. Figueroa, M.E. Bouza, M.I. Álvarez-Álvarez P0046 A combined screening strategy for invasive fungal infections in high-risk haematology patients: early computed thoracic tomograpy and serum 1,3-beta-D-glucan G. Metan* (Kayseri, Turkey), M. Keklik, G. Dinc, C. Pala, A. Yildirim, B. Saraymen, Y. Koker, B. Eser, M. Cetin P0047 Elderly versus non-elderly patients with aspergillosis in the ICU G. Dimopoulos* (Chaidari, Greece), T. Christodoulopoulou, D. Matthaiou, D. Vogelaers, S. Blot P0048 Imaging findings of invasive pulmonary aspergillosis in immunocompromised children A. Volkova* (St. Petersburg, Russia), M. Popova, E. Lyapina, O. Shadrivova, T. Bogomolova, S. Ignatyeva, L. Zubarovskaya, B. Afanasyev, N. Klimko P0049 Utility of volumetric analysis of computed tomography scans for prediction of treatment success and survival in invasive pulmonary aspergillosis J.J. Vehreschild, C.P. Heussel, G. Würthwein, M.J.G.T. Vehreschild, G. Silling, A.H. Groll, M. Brecht, O.A. Cornely* (Cologne, Germany) P0050 Prospective study of the performance of the serum galactomannan assay as part of a diagnostic-driven strategy for high-risk haematology patients on posaconazole primary prophylaxis I. Sánchez-Ortega* (Barcelona, Spain), I. Cuesta, B. Patiño, M. Arnan, A. Fernández de Sevilla, C. Gudiol, J. Ayats, M. Cuenca-Estrella, R.F. Duarte 24th ECCMID / Barcelona Final Programme Posters New strategies in the diagnosis of invasive candidiasis in neonatal intensive care L. Trovato* (Catania, Italy), P. Betta, V. Petrolito, D. Sciortino, S. Oliveri Diagnosis of Pneumocystis jirovecii pneumonia in onco-haematological patients: efficiency of combined detection of (1-3)-beta-D-glucan in the serum and Pneumocystis jirovecii DNA in respiratory samples C. Angebault* (Paris, France), E. Chachaty, J.-R. Zahar, A. Stoclin, B. Gachot, M.-E. Bougnoux, M. Merad 129 Chairs, Speakers & Authors P0035 P0043 Exhibition Identification of Candida parapsilosis complex species by RAPD, RFLP and VITEK® MS L. Bonato de Souza, J. Nobrega De Almeida Junior* (São Paulo, Brazil), A. Lopes Motta, F. Rossi, G. Benard, G.M. Bárbaro Del Negro General Information P0034 Poster Sessions Saturday, 10 May 2014 P0051 P0052 P0053 Bronchoalveolar lavage lateral-flow device test for diagnosing invasive pulmonary aspergillosis in patients with haematologic malignancies: a multicentre study M. Hoenigl* (Graz, Austria), D. Buchheidt, B. Willinger, J. Prattes, M. Lackner, W. Duettmann, V. Posch, B. Spiess, R. Krause, C. Lass-Flörl Performance of serum and bronchoalveolar lavage galactomannan and 1,3 beta-glucan enzyme assays with computer tomography scans in the diagnosis of invasive aspergillosis in immunocompromised hosts M. Batista* (São Paulo, Brazil), C. Lima Diogo, C. Abreu Fonseca, S. Figueiredo Costa, C. Melo Gamba, S. Vidal Campos, I. Leonardo Silva França, F. Luiz Dulley, M.L. Moretti, M.A. Shikanai-Yasuda Performance of galactomannan, Aspergillus lateral flow device test, beta-D-glucan, conventional culture and PCR for diagnosis of invasive pulmonary aspergillosis in bronchoalveolar lavage: a cohort study M. Hoenigl* (Graz, Austria), J. Prattes, B. Spiess, J. Wagner, V. Posch, W. Buzina, C. Koidl, R. Raggam, R. Krause, D. Buchheidt P0054 Invasive aspergillosis in HIV-infected patients in France: incidence, diagnosis, and outcome over 20 years B. Denis* (Paris, France), M. Guiguet, F. Mechaï, M. Revest, G. Melica-Gregoire, N. De Castro, A. Mahamat, D. Costagliola, O. Lortholary P0055 Evaluation of the in vitro potency of itraconazole, voriconazole, and posaconazole and against rare Aspergillus species N. Wiederhold* (San Antonio, TX, United States), A. Fothergill, D. McCarthy, C. Sanders, D. Sutton 15:30 – 16:30 P0057 Candida parapsilosis candidaemia: analysis of a decade at a tertiary hospital G. Fresco* (Madrid, Spain), J. Fortun Abete, P. Martín-Dávila, E. Gomez-Garcia de la Pedrosa, V. Pintado, J. Cobo, S. Moreno P0058 Epidemiology, species distribution and outcome of nosocomial Candida bloodstream infection in Shanghai Y.A.N.G. Zhi-Tao* (Shanghai, China), X.-Y. Liu, E.-Z. Chen, O. Lortholary P0059 Candida bloodstream infections: species distribution and antifungal resistance in intensive care unit (ICU) and in non-ICU wards at an university hospital in Rome M.T. Mascellino* (Rome, Italy), M.C. Ghezzi, A. Oliva, G. Raponi P0060 Candidaemia at two major teaching hospital networks in New York A. Safdar* (New York, United States), R. Press P0061 A seven-year survey of Candida bloodstream infections at a large Italian university hospital G. De Angelis* (Rome, Italy), T. D’Inzeo, B. Fiori, V. Prete, E. Liberto, E. De Carolis, R. Torelli, B. Posteraro, T. Spanu, M. Sanguinetti P0062 Nosocomial candidaemia in a paediatric unit of a university hospital: analysis of 144 episodes over a 3-year period E. Kocabas* (Adana, Turkey), U. Cay, G. Timurtas Dayar, G. Seydaoglu, F. Kibar P0063 The incidence of Candida yeasts on the tongue and in the intestinal tract in patients with psoriasis N. Ovcina-Kurtovic* (Sarajevo, Bosnia and Herzegovina), E. Kasumagic-Halilovic, S. Samardzic P0064 Candidaemia in the Coimbra Burns Unit in Portugal: predictive factors for infection and mortality C. Chaves* (Coimbra, Portugal), L.V. Saraiva, M. Caetano, N. Silva, L. Cabral P0065 Candidaemia at a referral hospital in Sub-Saharan Africa: emergence of Candida auris as a major pathogen N. Okinda, E. Kagotho, M. Castanheira, A. Njuguna, G. Omuse, P. Makau, M. Pfaller, G. Revathi, R. Adam* (Nairobi, Kenya) Poster Area POSTER SESSION I: Confronting fungal infections P0056 Candidaemia in patients with haematological malignancies: epidemiology and outcome G. Klyasova* (Moscow, Russia), E. Blokhina, A. Gracheva, S. Kravchenko, E. Parovichnikova, G. Galstyan, V. Okhmat 130 24th ECCMID / Barcelona Final Programme Poster Sessions Evaluation of twenty-eight cases of mucormycosis E. Kursun* (Adana, Turkey), T. Turunc, Y. Ziya Demiroglu, H. Arslan P0068 P0069 P0070 P0071 P0072 P0073 P0074 P0075 Post-traumatic mucormycosis: nationwide study in France and review L. Lelievre* (Paris, France), H. Abdoul, D. Garcia-Hermoso, A.C. Mamez, M. Hivelin, L. Lantieri, O. Lortholary, F. Lanternier Mucormycosis: ten-year experience at a tertiarycare centre in Turkey S. Kömür, A.S. Inal* (Adana, Turkey), B. Kurtaran, U. Ulu Candevir, A. Uguz, Y. Tasova, H.S.Z. Aksu Rhinocerebral and gastrointestinal mucormycosis: a case report C. Meddings, S. Raghuvanshi, T. Shimizu, R. Patel* (Dartford Kent, United Kingdom), L. Cotter Apophysomyces: an emerging Mucormycetes species causing necrotizing fasciitis, a primary cutaneous disease among humans – report of 17 cases from single institution of North India J. Chander* (Chandigarh, India), N. Singla, M. Kaur, K. Bala, R. Kaushik, U. Dalal, U. Handa, R.P.S. Punia, J. Guarro Fungiscope – global emerging fungal infection registry K. Wahlers* (Cologne, Germany), M.J.G.T. Vehreschild, A. Hamprecht, S. De Hoog, H. Wisplinghoff, J.J. Vehreschild, O. Cornely Burden of serious fungal infections in Denmark M.C. Arendrup* (Copenhagen, Denmark), T. Benfield, D.W. Denning Evaluation of knowledge and awareness of invasive fungal infections amongst doctors in the residency programme in Nigeria R.O. Oladele* (Lagos, Nigeria), A.T. Olayinka, A.A. Otu, H.A. Ekundayo, O.B. Makanjuola, E. Ochang, E. Asuquo, O.A. Atoyebi, D. Denning The burden of invasive and serious fungal disease in the UK D.W. Denning* (Manchester, United Kingdom), M. Pegorie, W. Welfare P0077 The burden of serious fungal infections in Ukraine A. Osmanov* (Simferopol, Ukraine), D.W. Denning P0078 The burden of serious fungal infections in the Czech Republic A. Chrdle* (Ceske Budejovice, Czech Republic), N. Mallatova, D.W. Denning P0079 The burden of serious fungal infections in Germany M. Ruhnke* (Berlin, Germany), A. Groll, P. Mayser, M. Schaller, W. Mendling, A. Ullmann, D.W. Denning P0080 Changing pattern of fungaemia in haematological patients; a six-year surveillance study A. Ulu-Kilic* (Kayseri, Turkey), A. Atalay, H. Demiraslan, C. Pala, G. Metan, E. Alp Mese P0081 Trichosporon asahii urinary tract infections in a tertiary hospital E. Belesiotou* (Athens, Greece), E. Perivolioti, M. Nepka, Z. Psaroudaki, A. Argyropoulou, T. Pittaras, A. Skoutelis P0082 Invasive pulmonary infection caused by Chrysosporium articulatum: the first case report C. Suankratay* (Bangkok, Thailand), O. Dhissayakamol, N. Uaprasert, N. Worasilchai, A. Chindamporn P0083 Agents of tinea capitis and their distribution according to age groups in the Aegean region of Turkey, 1974-2011 E. Tumbay, R. Inci, S. Hilmioglu-Polat* (Izmir, Turkey), G. Kitapcioglu P0084 Skin infection on both legs caused by Acremonium strictum: case report S. Polat-Hilmioglu, D.Y. Metin, M. Tasbakan* (Izmir, Turkey), H. Pullukcu, T. Akalin, E. Tümbay P0085 Epidemiology of fungal organisms isolated from 5923 otorrhea samples, a case control study: are Candida species infective organisms? Y. Hirai* (Tokyo, Japan), S. Asahata, Y. Ainoda, T. Fujita, A. Goto, K. Totsuka Estimating the burden of fungal diseases in Vietnam J. Beardsley* (Ho Chi Minh City, Vietnam), D.W. Denning, N.V. Chau, J.A. Crump, J.N. Day 24th ECCMID / Barcelona Final Programme 131 Chairs, Speakers & Authors P0067 P0076 Exhibition A decade of invasive aspergillosis in patients with kidney transplantation A. Desbois* (Paris, France), S. Poirée, R. Sberro-Soussan, E. Catherinot, M.E. Bougnoux, F. Lanternier, C. Legrendre, O. Lortholary, A. Scemla General Information P0066 Posters Saturday, 10 May 2014 Poster Sessions Saturday, 10 May 2014 P0086 An 8-year survey on the epidemiology and management of tinea capitis and tinea faciei in the Zurich area, Switzerland S. Kieliger, A. Cozzio, P. Bosshard* (Zurich, Switzerland) P0087 Impact of prior voriconazole exposure on frequency of mixed fungal infections in patients with invasive mucormycosis M. Abidi* (Milwaukee, United States), M. Sohail, N. Cummins, M. Wilhelm, N. Wengenack, M. Litzow, L. Letendre, B. Lahr, E. Poeschla, R. Walker 15:30 – 16:30 P0093 Lithium protects neurons from apoptosis in experimental pneumococcal meningitis F.D. Liechti* (Berne, Switzerland), N. Stüdle, D. Grandgirard, W. Thormann, S.L. Leib P0094 In experimental pneumococcal meningitis the effects of adjuvant daptomycin and dexamethasone differ and are influenced by disease severity P. Agyeman, D. Grandgirard* (Berne, Switzerland), S.L. Leib P0095 Experimental study of the efficacy of moxifloxacin in the therapy of Listeria monocytogenes meningitis M. Vivas Roca* (Barcelona, Spain), E. Force, C. El Haj, D. Garcia-Somoza, I. Pelegrín, J. Ariza, C. Cabellos P0096 Pituitary adenylate cyclase-activating polypeptide (PACAP) treatment ameliorates Toxoplasma gondii induced encephalitis in mice M.M. Heimesaat* (Berlin, Germany), A. Parlog, K. Wein, A. Tamas, G. Toth, D. Reglodi, I.R. Dunay P0097 Efficacy of solithromycin (CEM-101) for experimental otitis media (EPM) due to nontypable Haemophilus influenzae (NTHI) and Streptococcus pneumoniae (SP) M. Figueira* (Boston, United States), S. Pelton P0098 Activity of fluconazole, amphotericin B, caspofungin and anidulafungin against Candida albicans in an experimental foreign-body infection model E. Maiolo* (Lausanne, Switzerland), U. Furustrand Tafin, O. Borens, A. Trampuz P0099 In vivo and in vitro efficacy of preventive use of azithromycin in pneumonia caused by Pseudomonas aeruginosa N. Kaku* (Nagasaki City, Japan), K. Yanagihara, Y. Harada, Y. Morinaga, N. Uno, H. Hasegawa, K. Izumikawa, S. Kohno P0100 Assessment of the activity of an antibiofilm molecule against Pseudomonas aeruginosa (PA) in a mice model of pneumonia S. Pineau* (Nantes, France), M. Simon, D. Boutoille, C. Jacqueline, K. Asehnoune, A. Dufour, J. Caillon P0101 Granzymes A and B contribute to the pulmonary inflammatory response during Klebsiella pneumoniae pneumonia M.I. Garcia-Laorden* (Amsterdam, The Netherlands), A.F. De Vos, D.C. Blok, S. Florquin, T. Van Der Poll Poster Area POSTER SESSION I: Animal models: treatment P0088 P0089 Combination of daptomycin plus fosfomycin has synergistic, potent, and rapid bactericidal activity against methicillin-resistant Staphylococcus aureus (MRSA) in a rabbit model of experimental endocarditis (EE) J.M. Miro* (Barcelona, Spain), C. Garcia-de-la-Maria, J.M. Pericas, Y. Armero, D. Soy, C. Cervera, C.A. Mestres, C. Falces, F. Marco, A. Moreno Daptomycin is more bactericidal than vancomycin and vancomycin/rifampin combination in a murine model of methicillinresistant Staphylococcus aureus vascular prosthesis infection M. Revest* (Rennes, France), C. Jacqueline, J. Caillon, P. Tattevin, G. Potel, C. Michelet, D. Boutoille P0090 Daptomycin plus fosfomycin: a highly synergistic combination in an experimental implantassociated MRSA-osteomyelitis in rats T. Lingscheid* (Berlin, Germany), W. Poeppl, D. Bernitzky, R. Plasenzotti, H. Burgmann P0091 Minimal Biofilm Eradication Concentration (MBEC) measurement predicts treatment failure in murine biofilm infection model of implantassociated osteomyelitis N. Jørgensen* (Aarhus, Denmark), R. Meyer, F. Dagnæs-Hansen, K. Fuursted, E. Petersen P0092 132 Bioactive titanium alloy prevents Staphylococcus aureus prosthesis adherence: in vitro and in vivo studies A. Saleh-Mghir* (Garches, France), I. Ben Aissa, L. Gatin, G. Hélary, V. Migonney, A.C. Crémieux 24th ECCMID / Barcelona Final Programme Poster Sessions Saturday, 10 May 2014 Murine model of invasive pulmonary aspergillosis N.V. Vasilyeva* (St. Petersburg, Russia), I.A. Bosak, T.S. Bogomolova, I.V. Vybornova, O.N. Pinegina, L.V. Filippova, S.M. Ignatyeva, A.A. Stepanova, Y.L. Avdeenko, N.V. Eremina P0106 In vivo efficacy of isavuconazole and amphotericin B of in a non-neutropenic murine model of disseminated Absidia corymbifera P. Warn* (Manchester, United Kingdom), A. Sharp P0107 In vivo activity of novel benzothiazinones BTZ169 and BTZ043 against Nocardia brasiliensis L. Vera-Cabrera* (Monterrey, Mexico), N.A. Gonzalez-Martinez, H.G. Lozano-Garza, J. Villarreal-Martinez, N. Cavazos-Rocha, J. Ocampo-Candiani, R.M. Hinojosa-Robles, M. Makarov, S.T. Cole P0108 P0109 Vaccine strategies to block T. cruzi infections (the causative agent of Chagas disease in the Americas) in a rodent model J.G. Estrada Franco* (Tapachula, Mexico), B.C. Perez Gutierrez, J.C. Vazquez Chagoyan, A. Barbabosa Pliego, S. Gupta, N. Garg Eravacycline protects in a Bacillus anthracisinfected New Zealand white rabbit treatment model J. Sutcliffe* (Watertown, United States), J. Selden, M. Gooldy, D. Pawlowski, A. Radcliff, K. Edwards, K. Gillum P0111 TP-271, a novel fluorocycline, is efficacious in a treatment model of aerosolised Francisella tularensis infection in BALB/c mice T. Grossman* (Watertown, MA, United States), W. Lin, K. Siefkas-Patterson, J. Sutcliffe P0112 Ileal dosing of a nisin and miconazole combination is efficacious in the hamster Clostridium difficile associated disease model M. Pulse* (Fort Worth, TX, United States), T. Murphy, P. Nguyen, K. Peterson, J. Pierce, J. Simecka, D. Valtierra, W. Weiss, S. Self P0113 Effect of probiotic Lactobacillus strains with antioxidant activity on inflammation and gut flora in a mouse model of colitis A. Tomusiak* (Krakow, Poland), A. Machul, D. Mikolajczyk, G. Wiecek, E. Golinska, P.B. Heczko, M. Strus P0114 Chemically synthesised treatment-andprophylactic substance against monkeypox virus and other orthopoxviruses L. Shishkina* (Koltsovo, Russia), A. Kabanov, A.L. Sergeev, L. Bulychev, M. Skarnovich, N. Bormotov, A.R. Sergeev, O. Mazurkov, A. Agafonov, A. Sergeev 15:30 – 16:30 Poster Area Posters P0105 Gliotoxin neutralising antibodies enhance angiogenesis and neutrophil trafficking in invasive pulmonary aspergillosis R. Ben-Ami* (Tel Aviv, Israel), S. Amit, V. Dergachev, Y. Shadkchan, N. Osherov, I. Benhar Efficacy of the investigational fluoroquinolone finafloxacin in a murine inhalational model of melioidosis S. Harding, K. Barnes* (Porton Down, United Kingdom), A. Simpson, A. Vente POSTER SESSION I: Animal models: pathophysiology P0115 Role for coagulation factor XI during Klebsiella pneumonia independent of factor XII I. Stroo* (Amsterdam, The Netherlands), C. Van ‘t Veer, J.J.T.H. Roelofs, J.C.M. Meijers, F.J. Castellino, S. Zeerleder, T. Van der Poll P0116 Platelet MyD88 signalling is not involved in host defence during Gram-negative pneumoniaderived sepsis S.F. De Stoppelaar* (Amsterdam, The Netherlands), M.P.B. Jansen, J.J.T.H. Roelofs, C. Van ‘t Veer, T. Van der Poll P0117 Platelets contribute to host defence and local haemostasis in Gram-negative pneumoniaderived sepsis S.F. De Stoppelaar* (Amsterdam, The Netherlands), J.J.T.H. Roelofs, C. Hau, C. Van ‘t Veer, T. Van der Poll 24th ECCMID / Barcelona Final Programme 133 Chairs, Speakers & Authors P0104 Comparison of the efficacy of colistin and rifampicin in a mouse model of pneumonia caused by carbapenem-resistant Acinetobacter baumannii V. Cassisa, M. Eveillard, H. Pailhoriès* (Anger, France), M.-L. Joly-Guillou P0110 Exhibition P0103 Prevention of endotracheal tube biofilm development through a novel closed suctioning catheter in a pig model of Pseudomonas aeruginosa severe pneumonia L. Fernandez-Barat* (Barcelona, Spain), G. Li Bassi, E. Aguilera, J.D. Martí, D. Wyncoll, G. Ntoumenopoulos, M. Rigol, T. Comaru, F. De Rosa, A. Torres General Information P0102 Poster Sessions Saturday, 10 May 2014 P0118 Protective role of the gut microbiota in pneumonia-derived sepsis J.M. Lankelma* (Amsterdam, The Netherlands), T.J. Schuijt, B.P. Scicluna, C. Belzer, A.F. De Vos, W.M. De Vos, W.J. Wiersinga P0119 The distinct roles of mmp-2 and mmp-9 in mediating murine Campylobacter jejuni induced enterocolitis M. Alutis, U. Grundmann, A. Fischer, A.A. Kühl, U.B. Göbel, S. Bereswill, M.M. Heimesaat* (Berlin, Germany) P0120 P0121 P0122 P0123 P0124 Metalloproteinases gene expression in a model of genital Chlamydia infection in female BALB/c mice A. Marangoni* (Bologna, Italy), C. Cavallini, R. Tassinari, R. Aldini, P. Nardini, C. Foschi, A. D’Errico, R. Cevenini Comparison of in vivo and in vitro models for the evaluation of the virulence of Salmonella enterica serovar Typhimurium H.Y. Tsen* (Taichung City, Taiwan), M.H. Chen, P.H. Chen, H.Y. Hsih, C.W. Lin A mouse model of Candida glabrata intraabdominal candidiasis highlights persistence within abscesses and immune evasion as key aspects of pathogenesis C.J. Clancy* (Pittsburgh, United States), S. Cheng, N. Solis, S. Filler, M.H. Nguyen Hypoxia in Leishmania major-skin lesions impairs the NO-dependent leishmanicidal activity of macrophages A. Mahnke, R.J. Meier, V. Schatz, J. Hofmann, K. Castiglione, U. Schleicher, O.S. Wolfbeis, C. Bogdan, J. Jantsch* (Erlangen, Germany) The correlation between intensity of Opisthorchis felineus infection with the eggs per gram of faeces in hamster models E. Perina* (Tomsk, Russia), E. Klikich, N. Englevskiy, A. Bogdanov, I. Saltykova, A. Sazonov, L. Ogorodova P0125 Latent Epstein-Barr virus infection via nasopharynx in adult humanised mice Q.Z. Ruan* (Milton Keynes, United Kingdom), R.S. Ruan, C.P. Ye P0126 Activity of a f8-like lytic bacteriophage against metallo-beta-lactamase-producing Pseudomonas aeruginosa in an invertebrate infection model P.R. Neves* (São Paulo, Brazil), L.T. Cerdeira, T.G.M. Oliveira, M. Mitne-Neto, J. Sampaio, E.M. Mamizuka, C.E. Levy, N. Lincopan 134 24th ECCMID / Barcelona Final Programme P0127 Preliminary analysis of Paracoccidioides lutzii infection in Galleria mellonella by flow cytometry and cell analysis approaches A.C.A. De Paula e Silva* (São Paulo, Brazil), L. Scorzoni, F. Sangalli-Leite, H.C. Oliveira, J.L. Singulani, A.M. Fusco-Almeida, M.J.S. Mendes-Giannini P0128 Virulence of the dimorphic fungus Paracoccidioides spp in Galleria mellonella model L. Scorzoni* (Araraquara, Brazil), F. Sangalli-Leite, A.C.A. De Paula e Silva, J.D. Singulani, A.M. Fusco-Almeida, M.J.S. Giannini P0129 Effect of cytolysin A of Escherichia coli in the wax moth Galleria mellonella model A. Márquez-López* (Santander, Spain), A. Ocampo-Sosa, J.M. Andersen, L. Martínez-Martínez, K. Fuursted P0130 Whole genome expression profiles of Drosophila melanogaster consecutive to Pseudomonas aeruginosa infection allow selection of new model genes implicated in host-parasite relationship A. Ecovoiu, A. Ratiu* (Bucharest, Romania), I. Czobor, M.C. Chifiriuc 15:30 – 16:30 Poster Area POSTER SESSION I: Basic science: pathogenesis P0131 Role of single nucleotide polymorhisms (SNPs) of genes implicated in autophagy for the natural course of sepsis by ventilator-associated pneumonia (VAP) A. Savva, T.H.E.O. Plantinga, A. Kotanidou, M. Farcas, F. Baziaka, M. Raftogiannis, S. Orfanos, G. Dimopoulos, M. Netea, E. Giamarellos-Bourboulis* (Athens, Greece) P0132 Paraoxonase-1 and monocyte chemoattractant protein-1 alterations in patients with central venous catheters S. Iftimie* (Reus Tarragona, Spain), A. García-Heredia, A. Cordoba, I. Pujol, F. Ballester, A. Castro, J. Camps P0133 Role of PMNs in the control of microbial infections in multiple sclerosis patients V. Allizond, S. Scutera, S. Rossi, T. Musso, C. Crocillà, P. Cavalla, A.M. Cuffini, N. Mandras, V. Tullio, G. Banche* (Turin, Italy) Poster Sessions Investigation of cytokines and intracellular bacteria in relation to the administration of lactoferrin in women with infertility C. Contini* (Ferrara, Italy), S. Seraceni, N. Valente, M. Maritati, M. Comar, R. Marci, E. Giugliano, F. Vesce P0136 Evaluation of the influence of iron ions on the expression and activation of catalases produced by Escherichia coli strains, isolated from patients with ulcerative colitis M. Pilarczyk-Zurek* (Cracow, Poland), M. Strus, P. Heczko, M. Bulanda P0137 Immunomodulatory effects of extracts of Origanum vulgare (oregano) against Helicobacter pylori A. Salinas Ibáñez, F. Canale, A. Arismendi Sosa, M. Mattar, T. Alarcón* (Madrid, Spain), A. Vega P0138 Production of corticotropin-releasing factor and urocortin from human monocyte-derived dendritic cells is stimulated by commensal bacteria T. Ohkusa* (Kashiwa Chiba, Japan), S. Koido, K. Uchiyama, H. Arakawa, M. Kajihara, S. Kan, M. Ito, S. Homma P0139 Gut microbiota depletion by broad-spectrum antibiotics influences systemic innate immune responses in human volunteers J.M. Lankelma* (Amsterdam, The Netherlands), A.F. De Vos, A.J. Hoogendijk, W.M. De Vos, T. Van der Poll, W.J. Wiersinga P0140 Faecal microbiota and bacterial translocation in adult patients with liver cirrhosis F. Santangelo* (Rome, Italy), V. Iebba, V. Totino, A. Gagliardi, V. Giannelli, V. Di Gregorio, M. Merli, S. Schippa P0141 Susceptibility of Campylobacter concisus to the bactericidal activity of healthy human serum K. Kirk* (Aalborg, Denmark), H.L. Nielsen, H. Nielsen P0142 Serum-soluble CD14 as potential marker of refractory ascites in liver cirrhosis J. Pogorzelska* (Bialystok, Poland), M. Rozkres-Bobrowska, J. Jaroszewicz, R. Flisiak Supernatants of P. aeruginosa incubated with azithromycin sub-MIC concentrations fail to induce cytokine production in A549 and THP-1 cell lines M. Banjanac* (Zagreb, Croatia), G. Ergovic, M. Bosnar, V. Erakovic Haber P0144 Outer membrane protein A (OmpA) epitopes interacting with eukaryotic target cell are also recognised by colicins: anti-OmpA directed antimicrobials J. Bosák* (Brno, Czech Republic), D. Zmajs P0145 Lung macrophage GP96 is essential for host defence during Gram-negative pneumonia A.A. Anas* (Amsterdam, The Netherlands), M.H.P. Van Lieshout, L. Zihai, C. Van ‘t Veer, A.F. De Vos, T. Van der Poll P0146 Expression and role of S100A8/A9 complexes in clinical and experimental Gram-negative sepsis H.K. De Jong* (Amsterdam, The Netherlands), A. Achouiti, T.A.F. Weehuizen, G.C.K.W. Koh, C.M. Parry, S. Baker, J. Roth, T. Vogl, T. Van der Poll, W.J. Wiersinga P0147 Inhibition of innate immune activation by bacterial RNA modifications K. Rimbach, A. Dalpke, T. Eigenbrod* (Heidelberg, Germany) P0148 Structure function of the death domain of human IRAK-M J. Du, G.A. Nicolaes, D. Kruijswijk, T. Van der Poll, M. Versloot, C. Van ‘t Veer* (Amsterdam, The Netherlands) P0149 Toxinotype analysis on Clostridium perfringens isolated in Japan and possibility of control by probiotics K. Wada* (Tokyo, Japan), M. Takahashi, K. Oka, T. Osaki, M. Francesch, E. McCartney, H. Kunishima, M. Kaku, S. Kamiya P0150 Real causative anaerobes for intra-abdominal infections and pelvic inflammatory diseases based on culture method H. Mikamo* (Tokyo, Japan), M. Matsumizu, M. Nagashima P0151 Is hypokalaemia paradoxical metabolic acidosis in meningococcal disease result of increased urinary potassium excretion? K.R. Kolbe* (São Paulo, Brazil), J. Sztajnbok, L. Andrade 24th ECCMID / Barcelona Final Programme 135 Chairs, Speakers & Authors P0135 P0143 Exhibition Vitamin D deficiency reduces the immune response and the phagocytosis rate of microglial cells M. Djukic* (Göttingen, Germany), M.L. Onken, S. Schuetze, S. Redlich, T. Bertsch, C. Bollheimer, C. Sieber, R. Nau General Information P0134 Posters Saturday, 10 May 2014 Poster Sessions Saturday, 10 May 2014 P0152 Description of pulmonary bacterial floras associated with the presence of two pathogens, Pseudomonas aeruginosa and Staphylococcus aureus, in patients with cystic fibrosis L. Pages* (Lyon, France), C. Commun, C. Bardel, M. De Mont Clos, P. Reix, I. Durieux, F. Vandenesch, J. Freney, B. Cournoyer, A. Doleans-Jordheim P0153 Differential proteomic characterisation of patientrelated and environmental isolates of Legionella pneumophila S. Quero* (Badalona, Spain), M. García-Núñez, N. Párraga-Niño, M.L. Pedro-Botet, L. Mateu, M. Sabrià P0154 P0155 Functional and phenotypical characterisation of M. tuberculosis-specific T-cells in HIV-infected patients with active tuberculosis or latent infection naïve to antiretroviral treatment T. Chiacchio, E. Petruccioli, V. Vanini, G. Cuzzi, C. Pinnetti, A. Sampaolesi, D. Goletti* (Rome, Italy) Mycobacterium tuberculosis PE_PGRS33 promotes entry into macrophages through TLR2 I. Palucci, S. Camassa, A. Cascioferro, M. Sali, M. Minerva, R. Iantomasi, F. Ria, M. De Spirito, R. Manganelli, G. Delogu* (Rome, Italy) P0156 Mutation frequency in susceptible clinical isolates of Mycobacterium tuberculosis under anaerobic conditions L. Joseph, A.W. Sturm* (Durban, South Africa) P0157 The evaluation of the mechanical properties of spirochetes surface Borrelia burgdorferi s.s. by atomic force microscope (AFM) M. Tokarska-Rodak, M. Koziol-Montewka* (Lublin, Poland), K. Skrzypiec, E. Mendyk, T. Chmielewski, S. Tylewska-Wierzbanowska, P. Dobosz P0158 Synthesis of Th17 cytokines by peripheral blood mononuclear cells stimulated with Borrelia burgdorferi sensu lato S. Grygorczuk* (Bialystok, Poland), J. Osada, R. Swierzbinska, A. Moniuszko, J. Zajkowska, M. Kondrusik, P. Czupryna, J. Dunaj, M. Dabrowska, S.A. Pancewicz P0159 136 Borrelia induces TLR-2-mediated migration of dendritic cells in a novel human ex vivo skin model of Lyme borreliosis L.M.K. Mason* (Amsterdam, The Netherlands), C. Van ‘t Veer, T. Van der Poll, T.B.H. Geijtenbeek, J.W.R. Hovius 24th ECCMID / Barcelona Final Programme P0160 Characterisation of the role of type I and III interferon response during West Nile virus and Usutu virus infection G. Cacciotti* (Rome, Italy), C. Selvaggi, G. Ribelli, K. Monteleone, C. Lorenzi, M. Curtosi, A. Papa, A. Pierangeli, G. Antonelli, C. Scagnolari P0161 Genome-wide identification of pathogenicity factors of the free-living amoeba Naegleria fowleri D. Zysset-Burri, N. Müller, M. Heller, N. Schürch, M. Wittwer* (Spiez, Switzerland) P0162 Riboproteomic applied to the study of posttranscriptional regulation in Leishmania braziliensis C. Ramirez, J.M. Requena, C.J. Puerta* (Bogota, Colombia) 15:30 – 16:30 Poster Area POSTER SESSION I: Basic science: pathogenesis of Gram-negative bacteria P0163 Experiments on the effect of probiotics on extended-spectrum beta-lactamase producing Escherichia coli by using growth, beta-lactamase activity and conjugation assays N. Ishibashi* (Sendai Miyagi, Japan), K. Wada, H. Kunishima, K. Oka, M. Takahashi, K. Aoki, A. Yoshizumi, T. Aoyagi, M. Kitagawa, M. Kaku P0164 Differences in recombination events and mutation frequencies among pathogenic and commensal and environmental Escherichia coli strains M.C. Turrientes, J.M. González-Alba, A. Ripoll, M.R. Baquero, R. Cantón, F. Baquero, J.C. Galán* (Madrid, Spain) P0165 The flagellar protein FliD of an atypical enteropathogenic Escherichia coli strain acts as an adhesin during interaction with enterocytes’ microvilli in vitro S.C.F. Sampaio* (São Paulo, Brazil), B.G. Garcia, W.B. LUIZ, R.C.C. Ferreira, J.L.M. Sampaio, S.G. Rita, L.C.S. Ferreira, T.A.T. Gomes P0166 Relationship between phylogenetic groups, antibiotic resistance and patient characteristics in terms of adhesin genes in cystitis and pyelonephritis isolates of Escherichia coli D.K. Er* (Kocaeli, Turkey), D. Dundar, H. Uzuner, A. Osmani, L. Ozdemir Poster Sessions Comparative genomics reveals that O-antigen is essential for virulence of ST127 UPEC in Galleria mellonella larvae M. Alghoribi* (Plymouth, United Kingdom), S. Beatson, M. Upton P0169 P0170 P0171 P0172 P0173 P0174 Therapeutic concentrations of cefotaxime increase the conjugation frequency of a widespread IncI-1 plasmid encoding CMY-2 betalactamase in Escherichia coli M. Minoia, V. Bortolaia, L. Villa, A. Carattoli, L. Guardabassi* (Frederiksberg, Denmark) Modulation of the expression of adhesion and inflammatory response in endothelial cells by Pseudomonas aeruginosa quorum-sensing molecules F. Iordache* (Bucharest, Romania), F. Iordache, A.M. Holban, C. Curutiu, V. Lazar, L.M. Ditu, L. Marutescu, C.M. Chifiriuc Emergence of mucoid and small colony variants of P. aeruginosa in early infection development in cystic fibrosis A.M. Sousa* (Braga, Portugal), M.O. Pereira A novel virulence strategy for Pseudomonas aeruginosa mediated by an autotransporter with arginine-specific aminopeptidase activity E. Paredes-Osses* (Nottingham, United Kingdom), J. Luckett, O. Darch, C. Watters, M. AbuOun, V. Wright, S. Heeb, K. Rumbaugh, M. Camara, K. Hardie Phenotypical and gene expression study of the impact of Pseudomonas aeruginosa culture fractions on the human mesenchymal stem cells viability and cytokine profile A. Holban* (Bucharest, Romania), C. Bleotu, M. Chifiriuc, L. Ditu, L. Marutescu, C. Curutiu, V. Lazar Cytotoxicity is correlated with type three secretion system expression and inflammasome activation but not with motility in clinical isolates of Pseudomonas aeruginosa from acute infections A. Anantharajah* (Brussels, Belgium), J.M. Buyck, Y. Glupczynski, M.P. Mingeot-Leclercq, P.M. Tulkens, F. Van Bambeke Pathogenic Klebsiella pneumoniae bacteria evade recognition by the C-type lectin receptors DC-SIGN and SIGNR1 A.F. De Vos* (Amsterdam, The Netherlands), L. Kors, S. Terpstra, R. De Beer, L. Boon, S. Brisse, S. Alberti, T. Van der Poll, T. Geijtenbeek P0176 Microbial cooperation in cystic fibrosis: Stenotrophomonas maltophilia significantly modulates Pseudomonas aeruginosa virulence V. Crocetta* (Chieti, Italy), A. Pompilio, S. De Nicola, F. Verginelli, S. Guarnieri, E. Fiscarelli, G. Di Bonaventura P0177 Clinical impact of several virulence factors of Acinetobacter baumannii R. Alvarez Marin* (Seville, Spain), R. López Rojas, F. Fernández Cuenca, M.J. McConnell, J. Domínguez Herrera, M.J. Gómez Gómez, J. Garnacho Montero, J.A. Márquez Vácaro, J. Pachón P0178 Genomic evolution of Acinetobacter baumannii parental isolates in a decade M. Lopez* (La Coruña, Spain), A. Rueda, F. Fernandez-Cuenca, L. Martinez-Martinez, J. Vila, J.M. Cisneros, J. Rodriguez-Baño, A. Pascual, G. Bou, M. Tomas Carmona P0179 Unraveling bacteria-host cell interactions in Acinetobacter clinical isolates S. Remuzgo Martínez* (Santander, Spain), J.M. Icardo, L. Martínez-Martínez, J. Ramos-Vivas P0180 Relationship between resistance mechanisms and virulence in a NDM-1 producing-Acinetobacter pittii-like strain using the Caenorhabditis elegans model P. Espinal* (Barcelona, Spain), D. Rolo, M. Telli, N. Mosqueda, I. Roca, J. Vila 15:30 – 16:30 Poster Area POSTER SESSION I: Basic science: pathogenesis of streptococci, enterococci, Listeria and Propionibacterium P0181 Intracellular multiplication of group A Streptococcus in endothelial cell J.J. Wu* (Tainan City, Taiwan), H.W. Chen 24th ECCMID / Barcelona Final Programme Chairs, Speakers & Authors P0168 P0175 Exhibition MMRS-related genes in hypermutable Escherichia coli strains C. Lefebvre Garcia* (Sherbrooke, Canada), R.J.R. Vaillancourt, P.-E. Jacques, S. Rodrigue, M.S. Diarra, F. Malouin 137 General Information P0167 Posters Saturday, 10 May 2014 Poster Sessions Saturday, 10 May 2014 P0182 Isolation and proteomic analysis of extracellular membrane vesicles of Streptococcus pneumoniae E.C. Park* (Dajeon, Korea), C.W. Choi, S.H. Yun, Y.G. Lee, S.Y. Lee, G.H. Kim, S.I. Kim P0191 Human nasal microbiota and Staphylococcus aureus carriage: a study based on culture and mass spectrometry A.G. Ranc* (Bron, France), F. Laurent, M. Bes, A.M. Freydiere, G. Lina, F. Vandenesch, A. Tristan P0184 Toxin-antitoxin system as a sensitive target in pathogenic Enterococcus N. Sadeghifard* (Ilam, Iran), S. Soheili, S. Ghafourian, R.A. Hamat, Z. Sekawi P0192 P0185 The SOS regulon of Enterococcus faecalis is not involved in virulence traits L. Carrilero* (Madrid, Spain), S. Matrat, D. Thomas-Lopez, B. Gutiérrez, A. Santos-López, C.M. Ovejero, L. Hidalgo, N. Montero-Serra, I.F. Nes, B. Gonzalez-Zorn Community-associated Staphylococcus aureus isolates display distinct phenotypic profiles: link to agr type and alpha-toxin levels S. Mairpady Shambat, A. Haggar, F. Vandenesch, G. Lina, W. Van Wamel, G. Arakere, M. Svensson, A. Norrby-Teglund* (Stockholm, Sweden) P0193 Are Staphylococcus aureus PVL toxin-positive isolates causing acute bacterial skin and skin structure infections (ABSSSI) associated with more severe presentation or worse outcome? S. Puttagunta* (Branford, CT, United States), H. Boucher, M. Wilcox, G. Talbot, M. Dunne P0194 Community-associated MRSA strains are not more virulent than healthcare-associated MRSA strains in a range of laboratory assays E. Boakes, H. Marbach, S. Lynham, M. Ward, J.D. Edgeworth, J.A. Otter* (London, United Kingdom) P0195 Differential induction of innate defence antimicrobial peptides by bacterial culture supernatants of invasive vs non-invasive staphylococci in human keratinocyte and nasal epithelial cell lines C. Burgey* (Freiburg, Germany), W.V. Kern, W. Römer, S. Rieg P0196 Comparison of transcriptomics technologies for assessment of Staphylococcus aureus gene expression D. Hernandez, C. Le Priol, D. Baud* (Geneva, Switzerland), A. Fischer, F. Reynier, G. Gervasi, S. Chatellier, J. Veyrieras, P. François, J. Schrenzel P0197 Detection of pathogenicity factors of Staphylococcus epidermidis by whole genome sequencing M. Kornienko* (Moscow, Russia), V. Kopyltsov, I. Karpova, A. Larin, E. Kostryukova, E. Ilina, L. Lubasovskaya, T. Priputnevich, G. Sukhikh, V. Govorun P0198 Dual role of live intracellular Staphylococcus aureus on osteoclast lineage leading to increased bone resorption S. Trouillet-Assant* (Lyon, France), M. Gallet, P. Nauroy, J.P. Rasigade, S. Flammier, P. Parroche, J. Marvel, F. Vandenesch, P. Jurdic, F. Laurent P0186 P0187 P0188 Listeria monocytogenes induces host DNA damage and delays the host cell cycle to promote infection E. Leitão, A.C. Costa, C. Brito, R. Pombinho, D. Cabanes, S. Sousa* (Porto, Portugal) Microglia response to Listeria monocytogenes infection E. Frande Cabanes* (Santander, Spain), R. Calderón González, C. Álvarez Domínguez, M. López Fanarraga Differences in immunostimulatory and cell motility activity between Propionibacterium acnes type I and II on prostate epithelial cells S. Davidsson* (Örebro, Sweden), B. Söderquist, O. Andrén, P. Mölling, J. Carlsson 15:30 – 16:30 Poster Area POSTER SESSION I: Basic science: pathogenesis of staphylococci P0189 Polyclonal colonisation with Staphylococcus aureus S. Mernelius* (Jonkoping, Sweden), K. Jansson, S. Löfgren, P.-E. Lindgren, A. Matussek P0190 Prospective study of the Staphylococcus aureus nasal and rectal colonisation in intensive care unit patients: prevalence, bacterial load and genotyping of isolates P.O. Verhoeven* (Saint-Etienne, France), J. Gagnaire, C.H. Haddar, E. Botelho-Nevers, C. Auboyer, M. Darmon, C. Mariat, F. Grattard, B. Pozzetto, P. Berhelot 138 24th ECCMID / Barcelona Final Programme Poster Sessions Saturday, 10 May 2014 P0199 Phagosomal escape of hypervirulent Staphylococcus aureus is not dependent on betatoxin expression C. Dupieux* (Lyon, France), A. Sapin, S. Trouillet-Assant, G. Lina, J. Etienne, F. Vandenesch, F. Laurent, J.p. Rasigade P0208 Clonal dissemination and virulence factors among Staphylococcus lugdunensis from two Greek hospitals during a six-year period N. Giormezis* (Patras, Greece), F. Kolonitsiou, A. Makri, A. Vogiatzi, E.D. Anastassiou, I. Spiliopoulou P0200 Expression of virulence gene and cytotoxicity from Staphylococcus aureus ST clones J.I. Yoo* (Seoul, Korea), H.K. Kim, J.W. Kim, K.S. Kang, H.S. Kim, J.S. Yoo, J.Y. Yu, Y.S. Lee P0209 P0201 Staphylococcus aureus small colony variants are induced by low pH N. Leimer* (Zurich, Switzerland), A. Furrer, M. Schwarz, A.S. Bahlmann, F. Andreoni, U. Matt, K. Seidl, R.A. Schüpbach, A.S. Zinkernagel Staphylococcus pseudintermedius virulence gene content from Swedish and Spanish canine and human isolates: a comparative analysis E. Gomez-Sanz, S. Börjesson, K. Ekström, U. Andersson, C. Torres* (Logroño, Spain) P0206 P0207 ST2249-MRSA-III: a second major Staphylococcus aureus recombinant causing healthcare infection in the 1970s G.R. Nimmo* (Brisbane, Australia), J. Steen, S. Monecke, R. Ehricht, P. Slickers, J.C. Thomas, S.M. Grimmond, D.A. Robinson, G.W. Coombs Correlation of staphylococcal cassette chromosome MEC (SCCmec) types, accessory gene regulator (agr) groups and panton-valentine leukocidin (PVL) occurrence among MRSA isolates in Mumbai, India A. Subramanian* (Mumbai, India), R. Meharunkar, S.P. Vaidya, R. Warke, R.A. Deshmukh, A. Chowdhary Genetic variation of virulence and resistance genes in Staphylococcus epidermidis circulating in neonatal intensive care units H. Soeorg* (Tartu, Estonia), K. Huik, U. Parm, M.-L. Ilmoja, T. Metsvaht, I. Lutsar Evaluation of synergistic activity of various antibiotic combinations against multidrugresistant Acinetobacter baumannii G. Aydin* (Ankara, Turkey), Z. Bayindir, A. Yalci, I. Balik P0211 In vitro synergy of minocycline combinations against pan-drug-resistant Acinetobacter baumannii J.M. Balada-Llasat* (Columbus, United States), K. Thomas, D. Smith, P. Pancholi P0212 Exploring colistin-mediated potentiation of daptomycin against A. baumannii using molecular imaging and flow cytometry C. Malmberg* (Uppsala, Sweden), C. Annerstedt, P. Lagerbäck, O. Cars, P. Komp-Lindgren P0213 Colistin resistance in Acinetobacter baumannii is associated with a biological fitness cost and increased susceptibility to multiple drugs P. Komp Lindgren* (Uppsala, Sweden), P. Jonsson, C. Annerstedt, O. Cars P0214 In vitro effects of tigecycline and colistin in combinations with various antibiotics against MDR Acinetobacter baumannii isolates A. Büyük, F.F. Yilmaz, S. Gül-Yurtsever, M. Hosgor-Limoncu* (Izmir, Turkey) P0215 In vitro effects of antibacterial combinations against colistin resistance development of A. baumannii strains D. Gazel* (Canakkale, Turkey), M. Otkun 24th ECCMID / Barcelona Final Programme Posters P0205 Mutations in the fabI promoter often associate with alternative mechanisms of triclosan resistance in Staphylococcus aureus D. Grandgirard* (Berne, Switzerland), L. Furi, M.L. Cuisa, L. Baldassarri, D. Knight, I. Morrissey, C.R. Largiadèr, S.L. Leib, M. Oggioni P0210 Chairs, Speakers & Authors P0204 Prevalence of enterotoxin genes in Staphylococcus aureus isolated from stool samples in patients with diarrhoea M. Pirs* (Ljubljana, Slovenia), N. Svent Kucina, R. Kofol, M. Furlan, S. Ladinek, K. Seme POSTER SESSION I: Antibacterial drug activity and interactions in Gram-negative bacteria Exhibition P0203 Role of SCCmec in Staphylococcus aureus induced endothelial cell cytotoxicity K. Seidl, M. Leemann, Y. Achermann, A.S. Zinkernagel* (Zurich, Switzerland) Poster Area 139 General Information P0202 15:30 – 16:30 Poster Sessions Saturday, 10 May 2014 P0216 In vitro interactions of various antibacterial combinations against XDR and PDR A. baumannii isolated from ICU patients S. Vourli* (Athens, Greece), F. Frantzeskaki, K. Paraskevi, M. Tsala, A. Armaganidis, L. Zerva, G. Dimopoulos P0217 Fosfomycin synergy activity against multidrugresistant Acinetobacter baumannii strains G.C. Leite, C.K. Rocha, C. Rizek, A. Levin, S. Costa* (Rio de Janeiro, Brazil) P0218 Genotyping and in vitro activity of colistintigecycline and colistin-imipenem combinations against carbapenem-resistant Acinetobacter baumannii blood isolates B. Dinc, A. Tezer Tekce* (Ankara, Turkey), O. Unaldi, S.U.H.A. Sen, R.I.Z.A. Durmaz P0219 The ability of biofilm formation in clinical isolates of Acinetobacter baumannii and their colistin susceptibility in biofilm H.A. Kim* (Daegu, Korea), S.Y. Ryu, I.C. Seo, S.I. Suh, M.H. Suh, W.K. Baek P0220 In vitro activity of colistin, sulbactam, tigecycline, rifampicin and imipenem in combination against extensively resistant OXA23 Acinetobacter baumannii A. Inan* (Istanbul, Turkey), S. Senbayrak Akcay, S. Cevan, F. Kolayli, S.C. Ozyurek, S. Aksaray, H. Vahaboglu P0221 P0222 P0223 140 Ceftazidime-avibactam disk mass studies for EUCAST disk diffusion method against Enterobacteriaceae and P. aeruginosa L. Koeth* (Westlake, United States), G. Stone, E. Matuschek, G. Kahlmeter In vitro synergy studies of antimicrobial combinations against MDR/XDR high-risk clones of Pseudomonas aeruginosa Y. Meije, J. Basas, A. Oliver, N. Larrosa, X. Gomis, J. Rello, T. Pumarola, R. Cantón, A. Pahissa, J. Gavaldà* (Barcelona, Spain) In vitro performance by time-kill assays of fosfomycin-tobramycin combination in Pseudomonas aeruginosa clinical isolates with different tobramycin susceptibility M. Diez Aguilar* (Madrid, Spain), M. Morosini, Z. Aktas, C. Kayacan, R. Cantón 24th ECCMID / Barcelona Final Programme P0224 Comparison of broth microdilution and VITEK® 2 methods for susceptibility testing of minocycline against carbapenem-resistant Klebsiella pneumoniae and Acinetobacter baumannii clinical isolates P. Dimitriadis, S. Varlamis* (Thessaloniki, Greece), E. Protonotariou, O. Vasilaki, P. Tsiavi, E. Diza, S. Pournaras, L. Skoura P0225 High occurrence of colistin-heteroresistant subpopulations displaying stable resistance in carbapenemase-producing Klebsiella pneumoniae I. Pena* (Madrid, Spain), I. Rodriguez-Avial, C. Rodriguez-Avial, J.J. Picazo P0226 Tigecycline-colistin is active against ST258, KPC-producing Klebsiella pneumoniae with major OmpK36 porin mutations, which do not respond to doripenem-colistin R.K. Shields, M.H. Nguyen, B. Hao, L. Chen, B. Kreiswirth, C.J. Clancy* (Pittsburgh, United States) P0227 Time kill-assay of antibiotic combinations for multiresistant clinical isolates of Klebsiella pneumoniae harbouring OXA-48 carbapenemase Z. Aktas* (Istanbul, Turkey), C. Kayacan, A. Abulaila, M. Morosini, R. Cantón, M. Diez-Aguilar P0228 Co-resistance between biocides and antimicrobial agents among ESBL-producing Klebsiella pneumoniae F. Fernández-Cuenca* (Seville, Spain), M. Lossa, F.J. Caballero-Moyano, P. Egea, J.R. Hernández-Bello, J. Rodríguez-Baño, A. Pascual P0229 Susceptibility of carbapenemase-producing Enterobacteriaceae to non-beta-lactam antibiotics M. Kaase* (Bochum, Germany), A. Kaminski, N. Pfennigwerth, S.G. Gatermann P0230 Antibiotic susceptibility in urosepsis: molecular response of uropathogenic E. coli to ciprofloxacin in bloodstream infection models S. Gandi* (Edinburgh, United Kingdom), J. Brennecke, A. Tian, M. Petruskeviciute, S. Amyes, K. Templeton, T. Bachmann P0231 Consequences of the revised 2013 CLSI vs EUCAST guidelines for antibiotic susceptibility reporting for urinary Enterobacteriaceae Y. Keness* (Afula, Israel), A. Adler Poster Sessions Saturday, 10 May 2014 P0236 P0237 P0238 P0239 P0241 In vitro evaluation of the novel fluoroquinolone finafloxacin against Yersinia pestis K. Barnes* (Salisbury, United Kingdom), S.V. Harding, M. Richards, A. Vente P0243 Rapid assessment of the effect of quinolones on the chromosomal DNA fragmentation of an isogenic collection of Escherichia coli J. Rodriguez Martinez* (Seville, Spain), R. Santiso, J. Machuca, G. Bou, A. Pascual, J. Fernández In vitro activity of nitroxoline against uropathogens other than Escherichia coli and impact of pH M. Kresken* (Rheinbach, Germany), B. Körber-Irrgang P0244 Efficacy of fosmidomycin alone and in combination with colistin, tigecycline and rifampicin against multidrug-resistant and extensively drug-resistant Enterobacteriaceae J. Tyrrell* (Cardiff, United Kingdom), T. Walsh Clinical and microbiological efficacy of colistin alone and different combinations with colistin in ventilator-associated pneumonia G.R. Yilmaz* (Ankara, Turkey), T. Guven, R. Guner, Z. Kocak Tufan, F. Civelek Eser, M.A. Tasyaran P0245 Evaluation of antibacterial activity against extracellular and intracellular Legionella spp. M.A. Casares, G. Reina-Gonzalez, M. Fernández-Alonso* (Pamplona, Spain), C.A. Alonso, A. Ramos, J. Leiva Effects of external pH and bicarbonate on the bacterial growth and MIC of erythromycin K. Laub* (Budapest, Hungary), O. Dobay, J. Gili-Kovács, A. Tóthpál, S. Kardos, C. Bognár, K. Nagy, Á. Zsembery P0246 In vitro testing for synergism of antibiotic triple combination against multi-resistant Gram-negative pathogens C. Stein* (Jena, Germany), O. Makarewicz, M.W. Pletz Antibacterial susceptibility of Porphyromonas gingivalis and Prevotella species in patients with chronic periodontitis F. Gamboa* (Bogota, Colombia), D.A. García, A. Acosta, F. Aristizabal, M. Abba Antimicrobial resistance of Faecalibacterium prausnitzii A. Rintala* (Turku, Finland), E. Munukka, E. Eerola, P. Huovinen Antibiotic susceptibility and proposed ECOFF values for Burkholderia multivorans strains obtained from non-cystic fibrosis patients V. Hanulik* (Olomouc, Czech Republic), M.A. Webber, M. Wootton, M. Roderova, O. Holy, M. Kolar 15:30 – 16:30 Posters Incidence and antimicrobial susceptibility of Escherichia coli and Klebsiella pneumoniae with extended-spectrum beta-lactamases in community- and hospital-associated intraabdominal infections in China: SMART 2012 L. Zhang* (Beijing, China), Q.W. Yang, R.E. Badal, Y.C. Xu P0235 Antimicrobial susceptibility testing for Burkholderia cepacia complex (BCC) clinical isolates: comparison of broth microdilution, agar dilution, Etest (TM) and disk diffusion methodologies L.C.C. Fehlberg* (São Paulo, Brazil), A.C.R. Silva, F. Rodrigues-Costa, A. Nicoletti, A.P. Matos, R. Cayô, E.A. Marques, A.C. Gales Poster Area Chairs, Speakers & Authors P0233 P0234 P0240 POSTER SESSION I: Antibiotic choices: clinical studies P0247 Long-term alteration of intestinal microbiota in patients with ulcerative colitis by antibiotic combination therapy T. Ohkusa* (Kashiwa, Japan), S. Koido, K. Uchiyama, M. Kajihara, H. Arakawa, T. Kajiura, J. Shinozaki, M. Suzuki P0248 DAV132, developed to prevent side effects of antibiotics in the gut flora: results of a pilot crossover study in healthy volunteers A. Ducher* (Paris, France), C. Modess, W. Weitschies, W. Siegmund, J. Dressman, V. Augustin, C. Feger, A. Andremont, J. De Gunzburg 24th ECCMID / Barcelona Final Programme 141 Exhibition In vitro susceptibility of Escherichia coli isolated from patients with intra-abdominal infections in China: data from the study for monitoring antimicrobial resistance trends (SMART) 2002-2012 Y. Wang* (Chongqing, China), Q.W. Yang, R.E. Badal, Y.C. Xu, S. SMART Study Group in China General Information P0232 Poster Sessions Saturday, 10 May 2014 P0249 Retrospective cohort service evaluation regarding the use of temocillin in patients at high risk of Clostridium difficile infection E. Oscar* (Sheffield, United Kingdom), C. Winnard, R. Townsend P0250 Characterisation of antimicrobial use in patients with a history of Clostridium difficile infection (CDI) J.L. Wagner* (Detroit, United States), H. Alawy, C. Tschannen, S. Bockelman, C. Hirsch, S.L. Davis P0251 European Society of Clinical Microbiology and Infectious Diseases (ESCMID): update of the treatment guidance document for Clostridium difficile infection (CDI) S.B. Debast* (Amersfoort, The Netherlands, M.P. Bauer, E.J. Kuijper) P0252 Epidemiology of VAP and VAC N. Layios* (Liège, Belgium), P. Damas P0253 A randomised controlled trial of sitafloxacin and ertapenem treatment for acute pyelonephritis caused by extended-spectrum beta-lactamaseproducing Escherichia coli C. Malaisri, A. Wibulpolprasert, P. Santanirand, S. Kiertiburanakul* (Bangkok, Thailand) P0254 P0255 Extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBLPE) infection: is alternative to carbapenems achievable in practice? B. Pilmis, M. Groh, T. Delory, E. Weiss, J.R. Zahar* (Angers, France), P. Lesprit Outcomes of patients with bloodstream infection (BSI) of non-urinary source caused by extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL): a multicentre analysis comparing carbapenems to piperacillintazobactam (PTZ) H. Ofer-Friedman, S. Sharma, C. Shefler, A. Tirosh, D. Kandipalli, S. Sharma, P. Bathina, T. Lazarovitch, K.S. Kaye, D. Marchaim* (Zerifin, Israel) P0256 Coordination and management of a randomised controlled trial funded by European Commission’s 7th framework programme 2010: MagicBullet project, a multidisciplinary experience C. Rosso Fernández, F. Pérez Martinez, S. Monteau, M. Perales de los Santos, J. Garnacho Montero, J.M. Cisneros Herreros* (Seville, Spain) P0257 Elderly exclusion from randomised clinical trials on the treatment of antimicrobial resistant infections G. De Angelis* (Rome, Italy), C. Palazzolo, E. Di Meco, C. Donato, M. Paul, E. Tacconelli 142 24th ECCMID / Barcelona Final Programme P0258 Moxifloxacin monotherapy can be useful and safe in patients with ARDS J. Karlik* (Bochum, Germany), S. Martini, L. Bergmann, M. Adamzik P0259 Features of septic diseases in patients with neoplasms of the central nervous system A. Kolesnikov* (Makee, Ukraine), V. Cherniy, K. Kardash, T. Mustafin, V. Stasiuk, I. Koktishev P0260 Definition and significance of salvage treatment for Gram-negative infections in critically ill patients: preliminary results of an ESGCIP survey G. Poulakou* (Athens, Greece), D.K. Matthaiou, M. Bassetti, H. Erdem, G. Dimopoulos, J. Carlet, J. Lipman, J.F. Timsit, H. Giamarellou, J. Rello P0261 Clinical characteristics and outcomes of patients with bacteraemia by multidrug-resistant (MDR) microorganisms X. Kortajarena Urkola, L. Martín* (Donostia, Spain), A. Campins, J. Murillas, M. Riera, E. Delgado, A. Oliver, J.L. Pérez, L. Periañez, O. Delgado P0262 A randomised clinical trial on the effect of probiotics on surgical site infections after colorectal cancer surgery F. Yousefi* (Ahvaz, Iran), N. Honarvar, S. Salmanzadeh P0263 Perioperative antibiotic prophylaxis: a multicentre, prospective, cross-sectional study (Baltic antibiotic collaborative network project) A. Vilde* (Riga, Latvia), U. Dumpis, P. Mitt, P. Märtin, B. Lytsy, Z. Dambrauskas, G. Gailiene P0264 Preoperative antimicrobial prophylaxis for appendectomy in children N.A. Grishina* (Vologda, Russia) P0265 Management of prosthetic joint infections: a survey of UK practice C. Cordina* (Glasgow, United Kingdom), A. Marek, N. Khanna P0266 Influence of daily dosage and frequency of administration of rifampicin levofloxacin combination therapy on tolerance and efficacy in 154 patients treated for prosthetic joint infection E.M. Senneville* (Tourcoing, France), S. Nguyen, H. Dezeque, C. Loiez, E. Beltrand, H. Migaud Poster Sessions Saturday, 10 May 2014 P0267 Evaluation of drug interactions in hospitalised patients and antimicrobials’ role assessment M. Jamshidi Makiani* (Tehran, Iran), A.Z. Mahboobi Hajiaqa, M. Shafea, N. Mohebbi, M. Zangeneh P0268 Antibiotic use in psychiatric hospitals: pattern of antibiotic prescribing and potential of interaction between antibiotics and psychotropic drugs M. Stuhec, B. Beovic* (Ljubljana, Slovenia), B. Kores Plesnicar, M. Potocan, A. Zmitek, V. Winkler, S. Celan Stropnik, J. Topolovec, M. Prasnicki Poster Area POSTER SESSION I: EUCAST antimicrobial susceptibility testing P0279 EUCAST disk diffusion with pefloxacin 5 µg as screen for fluoroquinolone resistance in Salmonella spp. – variation between media, disks and testing sites E. Matuschek* (Växjö, Sweden), R. Skov, J. Åhman, M. Karlsson, A. Petersen, M. Torpdahl, G. Kahlmeter P0280 MIC and zone diameter correlations for Corynebacterium spp. using EUCAST methods and breakpoints E. Matuschek* (Växjö, Sweden), J. Åhman, G. Kahlmeter Recording of weight in patients being administered antibiotics with a narrow therapeutic index – a prospective cross-sectional study from acute care E. Charani* (London, United Kingdom), M. Gharbi, G. Frost, A.H. Holmes P0281 Evaluation of retapamulin E-test: validation against broth microdilution and inter-laboratory variation using EUCAST media J. Åhman, K. Bowker, A. Mazzariol, C. Müllner, A. Petersen, M. Tato Diez, E. Matuschek* (Växjö, Sweden) P0271 Worldwide availability and pricing of antifungal drugs E. Davies, M. Kneale, J.S. Bartholomew, D.W. Denning* (Manchester, Switzerland) P0282 P0275 Pharmaceutical quality and integrity of eight generics of ceftriaxone preparation for injection in eastern Asia I. Arnet* (Basel, Switzerland), M. Altermatt, Y. Roggo, G. Schnetzler EUCAST fluoroquinolone breakpoints in enterococci in urinary tract infections – determination of disk diffusion criteria for susceptibility testing O. Ekelund* (Växjö, Sweden), E. Matuschek, J. Åhman, G. Kahlmeter P0283 Evaluation of EUCAST zone diameter breakpoints for Pseudomonas spp. J. Åhman* (Växjö, Sweden), E. Matuschek, P.R. Rhomberg, R.N. Jones, G. Kahlmeter P0284 Evaluation of the EUCAST disk diffusion method for antimicrobial susceptibility testing of the Bacteroides fragilis group isolates Z. Eitel, E. Urbán, U. Justesen, E. Nagy* (Szeged, Hungary) P0285 Evaluation of different fluoroquinolone (FQ) antibiotics for detection of FQ resistance in Salmonella species by disk diffusion (DD) R. Skov* (Copenhagen, Denmark), E. Matuschek, J. Åhman, A. Petersen, M. Torpdahl, G. Kahlmeter P0286 Comparison of EUCAST and CLSI cephalosporin discs to detect ESBL phenotype in Escherichia coli and Klebsiella spp. L. Naumiuk* (Gdansk, Poland), A. Piorkowska, R. Torunska, M. Bronk P0276 P0277 P0278 Stability of different brands of meropenem reconstituted in isotonic saline M. Carlier* (Ghent, Belgium), V. Stove, A. Verstraete, J. De Waele Lack of stability of amoxicillin, ceftazidime and imipenem in peritoneal dialysis solutions G. Deslandes* (Nantes, France), E. Allain-Launay, D. Navas, R. Bouquié, E. Dailly, A. Lemarec, P. Jolliet, G. Roussey Subcutaneously administered antibiotics: a national survey of current practice from the French infectious diseases (SPILF) and geriatric medicine (SFGG) societies’ network E. Forestier, C. Roubaud-Baudron, T. Fraisse, M. Paccalin, L. Pagani, J. Gaillat* (Pringy, France), G. Gavazzi 24th ECCMID / Barcelona Final Programme Exhibition P0269 Posters POSTER SESSION I: Antibiotic interactions, formulations and administration 15:30 – 16:30 Chairs, Speakers & Authors Poster Area 143 General Information 15:30 – 16:30 Poster Sessions Saturday, 10 May 2014 P0287 Comparative evaluation of VITEK® 2 antimicrobial susceptibility test system results for Enterobacteriaceae according to CLSI, EUCAST and VITEK® 2 Advanced Expert System (AES) interpretive criteria O. Karatuna* (Istanbul, Turkey), A. Karatas, I. Akyar P0295 Challenges and solutions for development of new antibacterials: results of the Combacte opinion survey among pharmaceutical industry professionals E. Bettiol, J.D. Wetherington, N. Schmitt, S. Harbarth* (Geneva, Switzerland) P0288 Comparison of a custom made Trek panel with EUCAST disc diffusion for antimicrobial susceptibility testing of Staphylococcus aureus A. Larsen* (Copenhagen, Denmark), A. Petersen, R. Skov P0296 P0289 Utility of a newly developed Muller-Hinton E agar for the detection of MRSA carrying the novel mecA homologue mecC A. Larsen* (Copenhagen, Denmark), A. Petersen, M. Holmes, A. Kearns, G. Edwards, C. Teale, R. Skov Activity of BAL30072 alone and in combination with carbapenems against Gram-negative bacteria I. Morrissey* (Epalinges, Switzerland), C. Siegmund, E. Genet, M. Neri, S. Hawser, M. Jones, M. Page, A. Santerre Henriksen P0297 Determination of the effect of blaNDM-1 gene copy number on the activity of BAL30072 alone and in combination with meropenem against clinical NDM-1 positive bacteria L. Jones* (Cardiff, United Kingdom), M.G.P. Page, M.E. Jones, T. Walsh P0298 In vivo activity of Fab001, a novel FabI inhibitor, in a mouse model of Acinetobacter baumannii pneumonia C. Mouze-Soulama* (Paris, France), T. Sleger P0299 In vitro potency of novel, fully synthetic tetracyclines against MDR Gram-negative pathogens, including carbapenem-resistant Enterobacteriaceae X. Xiao* (Watertown, United States), C. Sun, D. Hunt, R. Clark, C. Fyfe, K. Kerstein, T. Grossman, J. Sutcliffe P0300 In vivo efficacy of novel, fully synthetic tetracyclines in a murine lung infection model challenged with KPC-producing Klebsiella pneumoniae T. Grossman, C. Fyfe, K. Kerstein, C. Sun, D. Hunt, R. Clark, X. Xiao* (Watertown, United States), J. Sutcliffe P0301 Eravacycline does not prolong corrected QT intervals in a thorough QT study conducted in healthy subjects P.T. Horn* (Watertown, United States), S. Redican, X. Wei, R. Zhou, J. Liang, T.G. Todaro P0302 POL7080 is highly efficacious in the murine pneumonia model C. Vingsbo Lundberg, F. Bernardini, K. Dembowsky, G. Dale* (Allschwil, Switzerland) P0303 The impact of creatinine clearance on the dosing of POL7080, a new macrocyclic antibiotic A.E. Muller* (Tilburg, The Netherlands), G. Dale, J.W. Mouton P0290 Evaluation of the EUCAST recommendations for antimicrobial susceptibility of campylobacters on the 3 main Campylobacter species isolated in humans in France P. Lehours* (Bordeaux, France), E. Siffre, S. Ben Amor, H. Chardon, F. Megraud P0291 Development of an agar dilution susceptibility testing method for Fusobacterium necrophorum M. Wootton* (Cardiff, United Kingdom), V. Hall, T. Morris, R.A. Howe P0292 Validation of MIC evaluator strips for testing antimicrobial susceptibilities of fastidious organisms according to EUCAST guidelines M. Oleksiuk* (Basingstoke, United Kingdom), C. Hopper, E. Scopes 15:30 – 16:30 Poster Area POSTER SESSION I: New therapeutic alternatives P0293 Do you have the next antibiotic? The Worldwide Antibiotic Discovery Initiative M. Cooper* (St Lucia, Australia), J. Zuegg, A.G. Elliott, M.A. Blaskovich, T.A. Bradford P0294 Design and re-iterative data mining of a pathways-based, highly diverse chemical library used for antibacterial activity screenings G. Chiriano* (Geneva, Switzerland), A. Kranjc Petrucci, L. Slepikas, O. Patthey Vuadens, P. Cosson, T. Soldati, H. Hilbi, J. McKinney, L. Scapozza 144 24th ECCMID / Barcelona Final Programme Poster Sessions Population pharmacokinetics and target attainment of the new antipseudomonal macrocyclic antibiotic POL7080 A.E. Muller* (Tilburg, The Netherlands), G. Dale, J.W. Mouton P0313 Antibacterial action of nanosized metal-modified TiO2 composites M. Sredkova* (Pleven, Bulgaria), H. Hitkova, A. Stoyanova, V. Popova, N. Ivanova, A. Bachvarova-Nedelcheva, R. Iordanova P0305 Anticlostridial activity and mode of action of sucrose monolaurate in vitro E. Skrivanova* (Prague, Czech Republic), M. Marounek, P. Hovorkova P0314 Antibacterial efficacy of gallium-doped bioactive glass S. Begum* (Birmingham, United Kingdom), T. Worthington, W.E. Johnson, R.A. Martin P0306 Antimicrobial efficiency of plant-derived isothiocyanates against uropathogenic Escherichia coli – a promising approach for treatment of UTIs? A. Mampel, N.T. Mutters* (Heidelberg, Germany), K. Biehler, U. Frank P0315 Potentiation of rifampicin and fusidic acid through encapsulation with nanocine™ N.F. Kamaruzzaman* (London, United Kingdom), L. Good P0316 Antibacterial efficiency of hydroxyapatite biomaterials with biodegradable polylactic acid polymer, saturated with gentamicin I. Skadins* (Riga, Latvia), J. Kroica, I. Salma, A. Reinis, M. Sokolova, N. Berza P0317 In vitro photodynamic effect of rose bengal on Streptococcus spp and Candida spp P. Soria Lozano* (Zaragoza, Spain), C. Alejandre, M. Vidal García, M.J. Revillo, Y. Gilaberte, A. Rezusta P0318 Comparative in vitro study on photodynamic inactivation of some important periodontopathogens (clinical and reference strains) with Zn-phthalocyanines M. Belcheva* (Sofia, Bulgaria), V. Kussovski, V. Mantareva, I. Angelov, M. Durmus, H. Harmsen P0319 In vitro activity of epigallocatechin gallate (EGCG)-silver nanoparticle combinations versus bacteria associated with skin and medical device infections J.W. Betts* (London, United Kingdom), D.W. Wareham P0320 Antibacterial and anti-biofilm activity of PEIbased nanoparticles against bacterial species J. Barros* (Porto, Portugal), M.M. Azevedo, A. Silva-Dias, A.P. Silva, I. Pina-Vaz, C. Pina-Vaz, A.G. Rodrigues P0321 Novel biopolymeric composites with antimicrobial and anti-biofilm properties based on polycaprolactone, chitosan and essential oils P. Stoica* (Galbinasi, Romania), M.c. Chifiriuc, M. Rapa, C. Bleotu, V. Lazar P0309 P0310 Synthesis and antimicrobial evaluation of novel substituted naphthoquinones R. Nadjib Mohammed* (Tlemcen, Algeria), B. Zahia, B. Mohammed, C. Noureddine Antibacterial evaluation of synthetic bis(indolyl) and pyrrolic derivatives Y. Caspar* (Grenoble, France), E. Le Pihive, L. Maigre, J. Blu, M. Jeanty, D. Schneider, F. Minassian, N. Pelloux-Léon, M. Maurin, J.-N. Denis Novel synthetic bis(indolyl) derivatives active against Francisella tularensis subspecies holarctica Y. Caspar* (Grenoble, France), V. Sutera, J.-N. Denis, M. Maurin P0311 Uptake of the antibiotic negamycin into bacterial cells C. Schumacher* (Düsseldorf, Germany), A. Berscheid, I. Zerfaß, K.-H. Glüsenkamp, H. BrötzOesterhelt P0312 Potential synergy activity of the novel ceragenin, CSA-13, against clinical isolates Acinetobacter baumannii, including multidrug-resistant A. baumannii C. Bozkurt-Guzel* (Istanbul, Turkey), P. B.Savage, B. Ozbek-Celik 24th ECCMID / Barcelona Final Programme 145 Exhibition P0308 Antimicrobial activity of the new derivative of 5-nitrothiazole – N-(5-nitrothiazole-2-il)-n’-(4(R)-benzole sulphonylamino) alkanediol diamide by anaerobic microorganisms isolated from patients T. Sakalova* (Grodno, Belarus), M. Haretskaya General Information P0307 Chairs, Speakers & Authors P0304 Posters Saturday, 10 May 2014 Poster Sessions Saturday, 10 May 2014 P0322 MazEF toxin-antitoxin system is a widespread and sensitive antimicrobial target in antibioticresistant Staphylococcus aureus S. Ghafourian* (Putra, Malaysia), Z. Sekawi, L. Good, N. Sadeghifard P0323 Antimicrobial activity and proteome analyses of methicillin-resistant Staphylococcus aureus treated with violacein B. Araujo Lima* (Campinas, Brazil), M. Brocchi P0324 Orthosiphon stamineus protects Caenorhabditis elegans against Staphylococcus aureus infection through immunomodulation C. Kong, M.-W. Tan, S. Nathan* (Selangor, Malaysia) P0325 The antimicrobial effects of Artocarpus communis extracts against Propionibacterium acnes Y.C. Lin* (Kaohsiung, Taiwan), F.L. Yen, H. Hsia, D. Hung P0326 P0327 P0328 Novel derivatives of isonicotinic acid are active against Mycobacterium bovis and Mycobacterium tuberculosis O. Rzhepishevska, O. Zinchenko* (Odessa, Ukraine), N. Shmatkova, T. Philippova, I. Seifullina, C. Larsson Isolation of new species and screening for new antimicrobial compounds in Gram-positive bacteria isolated from hypersaline environments in north-eastern Algeria E.S.M.A. Bendjama, L. Loucif, D. Gacemi-Kirane, J.M. Rolain* (Marseille, France) Isolation of producing NRP S and type-I PKS Streptomyces strains with potential antimicrobial activity from lacustrine sediments of the El Kala lakes in northeastern Algeria L. Loucif, E.S.M.A. Bendjama, D. Gacemi-Kirane, J.M. Rolain* (Marseille, France) P0329 Prevention of disease and lesions caused by P. multocida in rabbits by using carbohydrates C. Gallego* (Bogotá, Colombia), P. Patiño, N. Martinez, C. Iregui P0330 Identification of gene cluster responsible for production of antibacterial agents in Pragia fontium K. Olejnickova* (Brno, Czech Republic), E. Chaloupkova, D. Smajs P0331 Studies on antibiotic acyldepsipeptide (ADEP) producer Streptomyces hawaiiensis NNRL 15010 and its self-protection mechanism D. Thomy* (Düsseldorf, Germany), P. Sass, Y. Cheng, H. Brötz-Oesterhelt 146 24th ECCMID / Barcelona Final Programme 15:30 – 16:30 Poster Area POSTER SESSION I: Rapid antimicrobial susceptibility testing P0332 Next generation automated phenotypic antibiotic susceptibility testing utilising automated microscopy analysis of bacterial cells A. Shamsheyeva, S. Metzger* (Tucson, United States), C.S. Price, B. Turng, D. Howson P0333 Direct susceptibility testing from positive blood cultures with early reading and EUCAST breakpoints E. Jonasson* (Växjö, Sweden), Å. Johansson, G. Kahlmeter, M. Sundqvist P0334 Antibiotic susceptibility in Streptococcus pneumoniae can be predicted after 8h incubation E. Jonasson, A. Åkerlund, G. Cederbrant, G. Kahlmeter, M. Sundqvist* (Växjö, Sweden) P0335 5-hour antibiotic susceptibility testing of Enterococcus faecium, E. faecalis and Acinetobacter baumannii directly from positive blood cultures using automated microscopy A. Shamsheyeva, D. Gamage, S. Metzger, B. Turng, D. Howson, C.S. Price* (Denver, United States) P0336 Rapid method for susceptibility testing of bacteria directly from positive blood cultures C. Vismara, M.C. Sironi, A. Bielli* (Milan, Italy), M. Coppola, G. Lombardi P0337 A new technology for rapid antimicrobial susceptibility testing from blood cultures M. Crow* (Reading, United Kingdom), H. Bennett, N. Woodford P0338 Direct identification of cephalosporin-resistant and carbapenem-resistant E. coli or K. pneumoniae from positive blood cultures using matrix-assisted laser desorption/ionization timeof-flight (MALDI-TOF) mass spectrometry E. De Carolis* (Rome, Italy), S. Paoletti, D. Nagel, A. Vella, I. Palucci, G. De Angelis, B. Posteraro, T. D’Inzeo, T. Spanu, M. Sanguinetti P0339 Rapid identification by mass spectrometry and direct disk diffusion from positive blood cultures: a comprehensive approach to improve clinical outcome C. Mauri, S. Bracco, D. Bernasconi, E. Meroni, L. Principe, P. Bonfanti, F. Luzzaro* (Lecco, Italy) Poster Sessions Saturday, 10 May 2014 P0342 P0343 P0344 Quantitative MALDI-TOF MS applied for rapid detection of bacterial resistance K. Sparbier, C. Lange, B. Wegemann, M. Kostrzewa* (Bremen, Germany) Carbapenemase production: application of MALDITOF mass spectrometry for their detection in strains of Enterobacteriaceae and Pseudomonas species J.J. Christensen* (Slagelse, Denmark), M.B. Nielsen, S. Rasmussen, R. Dargis Categorical agreements and discrepancies of direct susceptibility tests in Pseudomonas aeruginosa from clinical respiratory tract samples L. Perez* (Porto Alegre, Brazil), A.L.P. Freitas, C.G. Dias P0345 Rapid assessment of resistance to ciprofloxacin and meropenem in Pseudomonas aeruginosa F. Otero, M. Tamayo, R. Santiso, G. Bou, J.A. Lepe, M. McConnell, J.M. Cisneros, J. Gosalvez, J.L. Fernandez* (La Coruña, Spain) P0346 Campylobacter spp. susceptibility testing: early accurate reports? C. Muñoz Paraíso, M.T. Perez Pomata* (Madrid, Spain), N. Sanz Rodríguez, M.T. Llorente Rodríguez, J.L. Gómez Garcés P0347 P0348 The rapid identification and confirmation of carbepenemase-resistant Enterobacteriaceae (CRE) using Brilliance™ CRE agar and Sensititre™ Gram-negative plates (GN4F) C. Hopper, A. Butler, K. Powell, M. Oleksiuk* (Basingstoke, United Kingdom) Direct determination of antimicrobial susceptibility of Gram-negative bacilli from respiratory samples on chromogenic agar plates with gradient antibiotic strips C. D’Humieres, M. Belhiba, F. Brocco, A. Andremont, N. Grall* (Paris, France) 15:30 – 16:30 Poster Area POSTER SESSION I: Susceptibility testing of multiresistant bacteria P0350 Detection of mecC-positive, methicillin-resistant Staphylococcus aureus (MRSA) isolates A. Kriegeskorte* (Münster, Germany), E.A. Idelevich, F. Layer, B. Strommenger, O. Denis, G.K. Paterson, M.A. Holmes, G. Peters, G. Werner, K. Becker P0351 Evaluation of betaLACTA™ test directly on urine samples C. Viala* (Paris, France), L. Surgers, S. Gallah, H. Cordel, S. Henquet, J.l. Meynard, P.M. Girard, D. Decre, G. Arlet P0352 Comparison of four methods for the determination of tigecycline susceptibility in multi-resistant E. coli and K. pneumoniae A. Hamprecht* (Cologne, Germany), E. Zander, T. Oestreicher, T. Seifert, P. Higgins P0353 Evaluation of usefulness of the Carba NP test for the carbapenemase detection in Enterobacteriaceae, Pseudomonas spp. and Acinetobacter spp. for routine laboratory diagnostics E. Literacka* (Warsaw, Poland), K. Malinowska, A. Baraniak, K. Bojarska, M. Herda, W. Hryniewicz, D. Zabicka, M. Gniadkowski P0354 Evaluation of a new phenotypic method to reveal AmpC presence and porin loss in Enterobacteriaceae with decreased susceptibility to carbapenems E. Carretto* (Reggio Emilia, Italy), D. Barbarini, M. Bardaro, F. Brovarone, G. Russello, F. Vailati, C. Farina P0355 Meropenem-colistin synergy testing of multidrugresistant Acinetobacter baumannii in routine microbiology by two-dimensional E-tests D. Halimi, E.-J. Bonetti, G. Renzi, A. Cherkaoui, V. Sauvonnet, R. Martelin, A. Van Belkum, G. Durand, S. Chatellier, J. Schrenzel* (Geneva, Switzerland) 24th ECCMID / Barcelona Final Programme 147 Posters Direct susceptibility testing of positive blood cultures in 30 minutes M.T. Pereira, M.A.C. Broeren, E. Retera, N.L.A. Arents* (Veldhoven, The Netherlands) A novel, direct diagnostic approach for rapid susceptibility testing and identification of pathogenic microorganisms in clinical specimens by mean of Liofilchem® pathogenic system AST F. MZali* (Bordeaux, France), L. Stecken, X. Berard, A. Boyer, J. Goret, A. Quinart, D. Gruson, S. Pereyre Chairs, Speakers & Authors P0341 P0349 Exhibition Bacterial counts by flow cytometry predict the susceptibility of bacteria to antibiotics directly from positive blood culture bottles G. March Rosselló* (Valladolid, Spain), M.C. García-Loygorri, M. Simarro, M.P. Gutiérrez, A. Orduña, M.A. Bratos General Information P0340 Poster Sessions Saturday, 10 May 2014 P0356 P0357 P0358 P0359 Comparison of VITEK® 2 antimicrobial susceptibility results against vanA/vanB gene PCR for detection of vancomycin-resistant enterococci (VRE) N. Sherry* (Heidelberg, Australia), P. Kelley, A. Jaksic An assessment of the reproducibility of teicoplanin, vancomycin, daptomycin and linezolid resistance determination using the VITEK® 2 for staphylococci in a routine diagnostic laboratory Y. Protaschik, B. Edwards* (Aberdeen, United Kingdom), P. Kalima, A. Gibb Interlaboratory validation for antimicrobial susceptibility testing of highly pathogenic bacteria and identification of pitfalls in the CLSI microdilution method S. Schmoldt, P. Bolton, T. Boskani, G. Ezpeleta, R. Grunow, P. Jureen, J. Papaparaskevas, O. Telleria, B.R. Thoma, A. Tsakris, T. Wahab* (Solna, Sweden), D. Jacob Drug susceptibility testing of Mycobacterium tuberculosis strains detected with rpoB mutations: comparison between solid and quantitative liquid culture-based methods L. Guglielmetti* (Paris, France), L. Raskine, N. Veziris, C. Bernard, E. Cambau, Group of the French NRC for Mycobacteria: Aubry A. – Brossier F. – Mougari F. – Renvoisé A. – Robert J. - Sougakoff W. – Jarlier V. 15:30 – 16:30 Poster Area POSTER SESSION I: Antibiotic consumption data P0363 Restrictive interventions in ambulatory care in Slovenia M. Cizman* (Ig, Slovenia), T. Plankar Srovin, T. Bajec, S. Pecar-Cad P0364 Surveillance of antimicrobial use in Belgian acute hospitals: 5-year trends A. Ingenbleek* (Brussels, Belgium), M. Goossens, B. Catry P0365 Evaluation of antibiotics usage at provincial level and provincial socio-economic development index in Turkey in 2011 A. Sahin* (Ankara, Turkey), A. Alkan, H. Gursoz, H. Celik, F. Isli, E. Sakalli, F. Savur, B. Melik, F. Efe, E. Yilmaz P0366 Antibiotic use in different regions of Turkey in 2011 (NUTS) H.d. Celik, H. Gursoz, A. Alkan, B. Melik, A. Sahin, F. Savur, M. Aksoy* (Ankara, Turkey), C. Seckin, F. Isli, S. Unal P0367 Evaluation of injectable antibiotic prescribing in Turkey in 2011 F. Isli* (Ankara, Turkey), A. Alkan, E. Sakalli, H. Gursoz, A. Sahin, M. Aksoy, P. Gobel, C. Seckin, D. Celik, B. Melik P0360 Evaluation of the GENSPEED® MRSA test kit and its ability to detect the novel mecA homologue mecC A. Petersen* (Copenhagen, Denmark), A.J. Medina, A.R. Larsen P0368 Antimicrobial use in Turkey: first results of the WHO/Europe-ESAC Project H. Demet Celik, A. Versporten* (Antwerp, Belgium), H. Gursoz, A. Alkan, B. Melik, F. Savur, M. Aksoy, G. Bolokhovets, H. Bak Pedersen, H. Goossens P0361 GSK2140944 MIC quality control ranges using a multi-laboratory study design J.E. Ross, R.K. Flamm, R.N. Jones* (North Liberty, IA, United States) P0369 P0362 Multicentre evaluation of tigecycline MIC results for staphylococci using a MicroScan® Dried Overnight performance evaluation device panel M. Lewinski, C. Polage, S. Riedel, L. Mann, D. Roe-Carpenter* (West Sacramento, United States) Antimicrobial use in Kyrgyzstan: first results of the WHO/Europe-ESAC Project B. Kambaralieva* (Ishlek, Kyrgyz Republic), A. Versporten, A. Mamasheva, G. Bolokhovets, N. Sautenkova, H. Goossens P0370 Prescribing of systemic antimicrobials for respiratory infections in children in primary care in Russia S. Rachina* (Smolensk, Russia), R. Kozlov, L. Jarkova, Y. Belkova, V. Tatochenko, E. PATRIOT study group: Dudnikova, I. Sakulina, S. Maltsev, T. Spichak, V. Seroklinov, O. Chirikova, N. Klimova, T. Shumatova, G. Batischeva, S. Khokhlova, L. Kryukova, F. Manerov, T. Kaganova, E. Pavlinova, E. Kondyurina, N. Chornaya, I. Kosenko 148 24th ECCMID / Barcelona Final Programme Poster Sessions Saturday, 10 May 2014 Antimicrobial use in Armenia: first results of the WHO/Europe-ESAC Project L. Ghazaryan* (Yerevan, Armenia), A. Versporten, H. Martyrosian, G. Bolokhovets, N. Sautenkova, H. Goossens P0373 Quinolone use in eastern Europe: first results of the WHO/Europe-ESAC Project A. Versporten* (Antwerp, Belgium), G. Bolokhovets, N. Sautenkova, H. Bak Pedersen, H. Goossens, And the WHO/Europe-ESAC Project Group Point prevalence survey of healthcare-associated infections (HAI) in Tuscany 2012: antibiotic use characteristics and antimicrobial prevalence rates M. Macchiarulo* (Pisa, Italy), A.D. Porretta, M.T. Petrolo, F. Casalini, F. Uccelli, E. Lucaccini, G. Privitera 15:30 – 16:30 Poster Area POSTER SESSION I: Basic science: biofilm treatment P0381 Effect of aztreonam exposure in Pseudomonas aeruginosa biofilms E. Rojo Molinero* (Palma de Mallorca, Spain), B. Moyà, M.D. Macià, J.L. Pérez, R. Cantón, A. Oliver Antimicrobial use in Bosnia and Herzegovina: first results of the WHO/Europe-ESAC Project T. Spasojevic* (Banja Luka, Bosnia and Herzegovina), A. Versporten, N. Grubisa, G. Bolkhovets, H. Bak Pedersen, H. Goossens P0382 Biofilm formation by Clostridium difficile strains in the presence of sub-inhibitory concentrations of metronidazole C. Vuotto* (Rome, Italy), I. Moura, F. Barbanti, P. Mastrantonio, G. Donelli, P. Spigaglia P0375 Comparison of outpatient systemic antibiotic use in 2010 between the United States and 19 European countries: different outcome measurements, different results N. Adriaenssens* (Antwerp, Belgium), S. Coenen, H. Goossens P0383 Anti-bacterial effect of the plasma discharge against biofilm-producing Pseudomonas aeruginosa Y. Nakano* (Sendai, Japan), S. Fujimura, T. Sato, D. Yoshino, A. Watanabe P0384 P0376 Antifungal use in France: first multi-centre survey in haematology, intensive care units and at hospital level in 2012 C. Dumartin* (Bordeaux, France), X. Bertrand, F. L’Hériteau, M. Péfau, M. Giard, S. Boussat, S. Alfandari, B. Schlemmer, S. Vaux, A.M. Rogues Arthroscopic débridement with graft retention and early oral levofloxacin plus rifampicin as first choice for the treatment of acute infections of anterior cruciate ligament reconstruction D. Perez Prieto* (Barcelona, Spain), A. Trampuz, E. Portillo, A. Alier, M. Sorli, L. Puig-Verdié, J. Horcajada P0377 Cephalosporin use in eastern Europe: first results of the WHO/Europe-ESAC Project A. Versporten* (Antwerp, Belgium), G. Bolokhovets, N. Sautenkova, H. Bak Pedersen, H. Goossens, And the WHO/Europe-ESAC Project Group P0385 Hypericin photodynamic activity in combination with antimicrobial agents against Staphylococcus aureus biofilms S. Ballesta* (Seville, Spain), I. García-Luque, Y. Gilaberte, A. Rezusta, A. Pascual P0378 Widespread increase of carbapenem consumption in acute care hospitals in Catalonia, Spain E. Fondevilla* (Barcelona, Spain), S. Grau, S. Mojal, M. Palomar, L. Matas, F. Gudiol, G. VINCat Antimicrobial Program Group P0386 The efficiency of antimicrobial photodynamic therapy using visual light and water infiltrated infrared A on initial and mature oral biofilm A. Al-Ahmad* (Freiburg, Germany), L. Karygianni, S. Ruf, M. Bucher, E. Hellwig P0379 Using periodic point-prevalence surveys to assess appropriateness of antimicrobial prescribing in Australian private hospitals M. Cotta* (Melbourne, Australia), M. Robertson, L. Upjohn, C. Marshall, D. Liew, K. Buising P0387 Elimination and prevention of Acinetobacter baumannii biofilms on surfaces using a Myoviridae bacteriophage A. Coffey* (Cork, Ireland), M. Elbreki 24th ECCMID / Barcelona Final Programme Exhibition P0374 Posters P0372 P0380 Chairs, Speakers & Authors Antimicrobial use in Kosovo: first results of the WHO/Europe-ESAC Project L. Raka* (Pristina, Kosovo), A. Versporten, A. Jakupi, V. Uka, S. Hajdari, B. Sejdiu, G. Bolokhovets, H. Bak Pedersen, H. Goossens 149 General Information P0371 Poster Sessions Saturday, 10 May 2014 P0388 LED effects on E. coli’s ability to form biofilms and on phagocytic activity of neutrophils with NETs production in experimental localised pyoinflammatory processes M. Mishina* (Kharkiv, Ukraine), V. Myasoedov, V. Davydenko, A. Korobov, E. Dubovik, Y. Mozgova, Y. Mishin P0395 Q fever as a cause of acute hepatic inflammation in patients with community-acquired atypical pneumonia I. Hadji Petrusheva Meloska* (Skopje, Macedonia), K. Konstantin Icev, B. Branko Jaglikovski, B. Biljana Curcic-Trajkovska, A. Anica Hadji-Petrusheva Jankijevikj P0389 Assessment of the anti-adherence and antibiofilm activity of novel biocompatible PE and PVC polymers L.M. Ditu, M.C. Chifiriuc, C. Bleotu, A.M. Holban, C. Curutiu, L. Marutescu* (Bucharest, Romania), A. Netoiu, A. Ficai, G. Mihaescu P0396 Geographical repartition of Coxiella burnetii genotypes S. Edouard* (Marseille, France), D. Raoult P0397 Animal reservoirs of Q fever: unveiling Coxiella burnetii population structure in Portugal A. Cumbassá, M.J. Barahona, A.S. Santos, A. Botelho* (Lisbon, Portugal) P0398 Reservoirs of the emerging pathogens Bartonella spp. and Yersinia pestis in Peru A. Martin-Alonso, M. Soto, P. Foronda* (La Laguna, Spain), E. Aguilar, G. Bonnet, R. Pacheco, B. Valladares, E. Abreu-Yanes, M.A. Quispe-Ricalde P0399 Bartonella pathogens in small mammals (rodentia and insectivora) and their fleas (Siphonaptera) and ticks (Ixodidae) in Lithuania I. Lipatova* (Kaunas, Lithuania), A. Paulauskas, J. Radzijevskaja, V. Gedminas P0400 Data analysis on the incidence of Leptospira infection in autonomous province of Vojvodina A. Rosic* (Novi Sad, Serbia) P0401 Leptospires and leptospirosis in Angola and Guinea-Bissau: the involvement of a European laboratory for research and diagnosis T. Carreira* (Lisbon, Portugal), E. Estanislau, B. Ca, E. Fortes-Gabriel, J. Garcia, M. Nunes, M.L. Vieira P0402 Polymorphisms of TLR4 Asp299Gly gene and TNFalpha -308G>A gene of leptospirosis patients N. Farhanah* (Semarang, Indonesia), M.H. Gasem, S.M.H. Faradz P0403 Prevalence of Borrelia miyamotoi in Ixodes ticks in Europe and the United States M. Eshoo* (Carlsbad, CA, United States), C. Crowder, H. Carolan, M. Rounds, V. Honig, B. Mothes, H. Haag, O. Nolte, B. Luft, L. Grubhoffer P0404 Epidemiology and treatment response of tularemia: an observational study from central Anatolia G. Iskender, M.C. Ogan, S. Ceken* (Ankara, Turkey), H. Gedik, S. Kilic, G. Yapar Toros, E. Turk Aribas, M. Ertek P0390 P0391 P0392 Antiseptic effect of hyper-pure chlorine-dioxide on bacteria and biofilm A. Ghidan* (Budapest, Hungary), A. Herczegh, M. Gyurkovics, H. Agababyan, Z. Lohinai Effect of the use of clorhexidine dressings (CHG Tegaderm™) on the formation of biofilm on endoluminal and exoluminal surfaces of central venous catheters M. Gordon Sahuquillo* (Valencia, Spain), M.T. Gisbert Garcia, A. Cortes Herrera, E. Villarreal Tello, J. Mazarrota Palomares, J.C. Mateo Pardo, S. Messeguer Cuenca, E. Gonzalez Barbera, J. Bonastre Mora, P. Ramirez Galleymore Susceptibility of biofilm-associated Clostridium difficile to antimicrobial agents A.D.A.M. Jones, R. Manuel, D. Ready* (London, United Kingdom) 15:30 – 16:30 Poster Area POSTER SESSION I: Emerging infectious diseases P0393 P0394 150 Q fever as a cause of prolonged fever – a neglected zoonosis in Romania C. Popescu, R. Dulama* (Bucharest, Romania), G. Popescu, M. Radulescu, R. Mihailescu, R. Nastase, R. Moroti, V. Molagic, A. Lobodan, V. Arama Neurological involvement of acute Coxiella burnetii infection in the Balearic islands over a time span of 10 years (2003-2013) A. Ramirez Mena* (Bunyola, Spain), M. Raya Cruz, M. Riera Jaume, A. Payeras Cifre 24th ECCMID / Barcelona Final Programme Poster Sessions Saturday, 10 May 2014 P0408 Genitourinary brucellosis: results of the GONCA study H. Erdem, N. Elaldi, O. Ak, Y. Cag* (Brucellosis Study Group, Istanbul, Turkey) P0409 Administration of a triple vs standard double antibiotic regimen to brucellosis patients efficiently eliminates bacterial DNA load G. Vrioni* (Athens, Greece), A. Bourdakis, G. Pappas, V. Pitiriga, V. Kapsimali, S. Pournaras, A. Tsakris P0410 Elisa-IgG and -IgM assays are highly practical in clinical laboratories’ diagnosis of human brucellosis in a highly endemic region A.A. Chentoufi* (Riyadh, Saudi Arabia), M. Paz Rafael, S. Al Aidy, S. Usman, H. Albarghy, A. AlMazrou, A. Hoosen, G. Elghazali P0411 Actinomyces neuii: a case series and review of a rarely encountered pathogen N. Zelyas* (Edmonton, Canada), S. Gee, R. Rennie, B. Nillson, T. Bennett P0412 Investing in emerging infectious diseases: a systematic analysis of UK research J.R. Fitchett, M.G. Head* (London, United Kingdom), D.L. Heymann, R. Atun P0413 Janibacter terrae bacteraemia: two faces of the same organism I. Fernández-Natal* (León, Spain), J.A. Sáez-Nieto, S. Valdezate-Ramos, J.M. Guerra-Laso, R.H. Rodríguez-Pollán, I. Bresme-Trigo, F. Soriano P0414 P0415 Is the Raoultella genus an emerging threat of pathogens in elderly people? K. Türker* (Istanbul, Turkey), P. Bulut, B. Tas, M. Iktaç, C. Ozdalgiçoglu, B. Ozdemir Non-toxigenic tox-bearing Corynebacterium ulcerans infection in 13 game animals from Germany T. Eisenberg, P. Kutzer, M. Peters, A. Sing* (Oberschleissheim, Germany), M. Contzen, J. Rau P0417 The French Infectious Disease Society’s (FIDS) preparation and response to an emerging infectious disease H. Coignard-Biehler* (Paris, France), B. Hoen, S. Alfandari, P. Berthelot, M.C. Chopin, C. Rapp, B. Guery, P. Brouqui, O. Lortholary, C. Leport P0418 Brucellosis in endemic area: fifteen years’ experience S. Bolukcu* (Istanbul, Turkey), A. Inan, S.C. Ozyürek, S. Senbayrak Akcay, O. Barkay, E. Karagül 15:30 – 16:30 Poster Area POSTER SESSION I: Tick borne infections P0419 Prevalence of antibodies to Rickettsia conorii in human beings and dogs from the Terrassa area (Catalonia): a twenty-year perspective E. Espejo* (Terrassa, Spain), M. Andrés, J. Pérez, J. Prat, C. Guerrero, M.T. Muñoz, M.D. Alegre, J. Lite, F. Bella P0420 Rickettsial diseases in Tunisia: report of 220 cases A. Berriche, R. Abdelmalek, L. Ammari, F. Kanoun, S. Aissa, A. Ghoubontini, B. Kilani* (Tunis, Tunisia), H. Tiouiri Benaissa P0421 Tick-borne infectious disease in the Republic of Kazakhstan R. Egemberdieva* (Almaty, Kazakhstan), A. Dmitrovskiy, L. Eraliyeva, N. Turebekov, K. Abdiyeva, A. Oradova, Z.H. Shapiyeva, S. Tastanova, L. Ziyadina, T. Krasnova P0422 Molecular analysis of Rickettsia species detected in rickettsiosis cases and in arthropod vectors in Tunisia F. Khrouf* (Tunis, Tunisia), Y. M’Ghirbi, A. Znazen, L. Ameri, J. Souissi, A. Letaief, A. Bouattour P0423 Increased concentration of interferon beta and interferon lambda 3 in the cerebrospinal fluid of patients with tick-borne encephalitis S. Grygorczuk* (Bialystok, Poland), A. Moniuszko, R. Swierzbinska, J. Zajkowska, M. Kodrusik, P. Czupryna, J. Dunaj, S.A. Pancewicz 24th ECCMID / Barcelona Final Programme 151 Posters Investigation of Brucella seroprevalence in human and livestock in Igdir, Turkey G. Arvas, Y. Akkoyunlu* (Istanbul, Turkey), M. Berkoz, G. Acikgoz, A. Bora, F. Altindag Four-year serological follow-up of a Dutch acute Q fever cohort C.C.H. Wielders* (’s-Hertogenbosch, The Netherlands), G. Morroy, J.A.F. Van Loenhout, A. Rietveld, D.W. Notermans, A.C.A.P. Leenders, W. Van der Hoek, P.M. Schneeberger Chairs, Speakers & Authors P0407 P0416 Exhibition Is the fourfold increase of the tularemia incidence in Switzerland related to ticks? C.M. Beuret* (Spiez, Switzerland) General Information P0405 Poster Sessions Saturday, 10 May 2014 P0424 P0425 P0426 P0427 P0428 P0429 Epidemiology of the tick-borne relapsing fever in the area of La Campiña, southeast of Seville from 1994 to 2013 M.C. Domínguez Jiménez* (Seville, Spain), S. Vergara López, M.C. Gómez Sánchez, M.E. Roldán Fontana Endemicity of Anaplasma phagocytophilum (previously Ehrlichia spp.) and Babesia microti in Wisconsin, USA: benchmark results following introduction of molecular diagnostic methods for routine patient management (2012-2013) T.R. Fritsche* (Marshfield, United States), T.N. Marti, A.M. Schotthoefer, T.S. Uphoff REVIVE, a surveillance programme for ticks and tick-borne diseases: molecular detection of B. burgdorferi s.l. and Rickettsia spp. I. Lopes de Carvalho* (Lisbon, Portugal), A.S. Santos, M.M. Santos-Silva, R. De Sousa, M.S. Núncio, REVIVE Workgroup Study on ticks’ distribution and species identification infesting the bovine population of the district Muzaffarabad of Azad Jammu and Kashmir, Pakistan A.S.I.M. Shamim* (Rawalakot Ajk, Pakistan), A.M.I.R. Iqbal, R. Siddique A homologue of tick salivary lectin pathway inhibitor (TSLPI) in Ixodes ricinus protects Borrelia burgdorferi sensu lato from killing by human complement A. Wagemakers* (Amsterdam, The Netherlands), J. Coumou, G.A. Oei, A. Nijhof, T.J. Schuijt, E.A. Herkes, S. Narasimhan, E. Fikrig, A.D. Bins, J.W. Hovius Candidatus Neoehrlichia mikurensis – the emerging tick-borne pathogen in patients with autoimmune diseases and haematologic malignancies C. Wennerås* (Gothenburg, Sweden), P.O. Andersson, K. Vaht, M. Sender, E. Trysberg, L. Höper, E. Sakiniene, M. Stenson, M. Mattsson, A. Grankvist P0430 Persistence of immunologic response of scrub typhus patients at tertiary-care hospital, northestern Thailand W. Thipmontree* (Nakhon Ratchasima, Thailand), W. Tantibhedhyangkul, E. Wongsawat, S. Silpasakorn, D. Waywa, Y. Suputtamongkol P0431 Anaplasmatacea in ticks in Tunisia Y. Mghirbi* (Tunis, Tunisia), A. Bouattour 152 24th ECCMID / Barcelona Final Programme 15:30 – 16:30 Poster Area POSTER SESSION I: Emerging viruses / viral infections P0432 Toscana virus: emerging or undervalued virus? N.M. Scalisi, T. Romano, M. Di Franco, C.I. Palermo, C. Franchina, M.C. Laudani, C.M. Costanzo, R. Russo, G. Scalia* (Catania, Italy) P0433 Occurrence of chikungunya fever in Thailand and active surveillance in vector mosquitoes U. Thavara* (Muang Nonthaburi, Thailand), A. Tawatsin, P. Siriyasatien, A. Phumee, J. Chompoosri, P. Bhakdeenuan, S. Sangkitporn P0434 A serologic survey of West Nile virus and Usutu virus in Croatia T. Vilibic-Cavlek, V. Stevanovic* (Zagreb, Croatia), I. Pem-Novosel, I. Gjenero-Margan, B. Kaic, L.J. Barbic, S. Ljubin-Sternak, E. Listes, G. Mlinaric-Galinovic, G. Savini P0435 West Nile virus seroprevalence and behavioural risks in HIV-1 infected individuals, northern Greece, 2011 D. Pilalas* (Thessaloniki, Greece), S. Metallidis, L. Skoura, A. Kourelis, O. Tsachouridou, T. Chrysanthidis, P. Kollaras, D. Valagkouti, N. Malisiovas, A. Papa P0437 Epidemiology of imported dengue virus in Iran S. Chinikar* (Tehran, Iran), N. Shah-Hosseini, T. Jalali, S. Khakifirouz P0438 Ultrastructural studies on two ecotypes of dengue virus infection in human monocytic U937 cells C.-Y. Fish-Low, S. AbuBakar, F. Othman, H.-Y. Chee* (Selangor, Malaysia) P0439 Severe fever with thrombocytopenia syndrome on Jeju Island, Korea H. Sang Taek* (Jeju-si, Korea), L. Keun Hwa P0440 Double filtration plasmapheresis as a supportive therapy in patients with Crimean-Congo haemorrhagic fever who developed hepatic failure Z. Ozkurt* (Erzurum, Turkey), S. Erol, H. Kursad, A. Albayrak, E. Parlak, K.A. Güler, M. Keles, H. Dursun P0441 Evaluation of the Crimean-Congo haemorrhagic fever cases followed and treated in our clinic between 2009-2013 I. Celik* (Kayseri, Turkey), I. Yilbat Kiliç, F. Kürklü Bozkir, F. Bahadir, S. Gürbüz, Z. Bestepe Dursun Poster Sessions West Nile virus outbreak in Modena and Reggio Emilia: a descriptive study M. Vecchia* (Modena, Italy), M. Menozzi, G. Guaraldi, G. Magnani, F. Prati, C. Mussini P0444 P0445 P0446 P0447 P0448 P0449 Haemorrhagic fever with renal syndrome: an analysis of the outbreak in Croatia in 2012 N. Papic* (Zagreb, Croatia), R. Civljak, I. Kuzman, A. Topic, M. Vargovic, O. Dakovic Rode, A. Tadin, L. Cvetko Krajinovic, P. Svoboda, A. Markotic Raw date palm sap consumption practices and people’s perception of Nipah virus in two outbreak-affected districts in Bangladesh N. Nahar* (Basel, Switzerland), R.C. Paul, R. Sultana, F. Garcia, E.S. Gurley, J. Abedin, M. Asaduzzaman, N. Ali Rimi, M. Rahman, S. Zimicki, S.P. Luby Field study of faecal excretion as a decision support tool in response to silent reintroduction of wild-type poliovirus 1 into Israel J. Moran-Gilad* (Beit Kama, Israel), E. Mendelson, C.C. Burns, R. Bassal, M. Gdalevich, D. Sofer, S. Oberste, M. Hindiyeh, E. Kaliner, I. Grotto Novel astrovirus associated with encephalopathy in an immunocompromised patient, identified by deep sequencing of brain tissue J.R. Lockwood* (London, United Kingdom), S. Morfopoulou, W. Emmet, W. Ip, D. Shah, S.M.L. Paine, W. Tong, D. Clark, V. Plagnol, T. Jacques, W. Qasim, M. Hubank, J. Breuer Monitoring of supplementary immunisation effect on wild poliovirus circulation using complementary environmental and stool surveillance approaches following reintroduction of wild poliovirus type 1 into Israel E. Mendelson* (Beit Kama, Israel), J. Moran-Gilad, Y. Manor, R. Bassal, M. Hindiyeh, E. Kaliner, D. Sofer, M. Weil, M. Gdalevich, I. Grotto Serosurveillance of WNV in horses – useful tool for public health L. Barbic, V. Stevanovic* (Zagreb, Croatia), T. Vilibic-Cavlek, S. Kovac, I. Pem-Novosel, B. Kaic, E. Listes, L. Maltar, I. Lohman-Jankovic, V. Staresina Molecular detection of Salehabad / Adria virus in sandflies and West Nile virus in mosquitoes from eastern Thrace, Turkey K. Ergunay, K. Oter, S. Orsten* (Ankara, Turkey), O. Erisoz Kasap, F. Gunay, A.Z. Akkutay, A. Ozkul, B. Alten P0451 Pneumomediastinum and subcutaneous emphysema as initial presentation of furious rabies P. Davoodian* (Bandarabbas, Iran), H. Dadvand, M. Farsad, K. Seddighi, F. Naghshvar, M. Rezaei Nodoushan, A. Javadi P0452 Deriving dengue infection incidence using sequential serological data and routine disease notifications: a Bayesian evidence synthesis study M. Baguelin* (London, United Kingdom), C.F. Yung, L.C. Ng, J. Tay, Y.S. Leo P0453 The course of Crimean-Congo haemorrhagic fever cases in Georgia T. Tkhilaishvili* (Tbilisi, Georgia), M. Javakhadze, D. Kikabidze, M. Mamulashvili P0454 Feasibility of a new clinical severity scoring index to identify the patients with CrimeanCongo haemorrhagic fever who will benefit from ribavirin G. Kalin, G. Metan* (Kayseri, Turkey), H. Demiraslan, M. Doganay P0455 2 case reports of a rare complication in dengue infection of travellers at Bangkok Samui hospital, Thailand T. Narkwiboonwong* (Bangkok, Thailand) P0456 Detection of IgM antibodies, NS1 antigen and viral RNA in the diagnosis of acute dengue fever M. Trojanek* (Prague, Czech Republic), J. Maixner, N. Sojkova, D. Tomickova, H. Rohacova, V. Maresova, F. Stejskal P0457 The first cases of laboratory-confirmed dengue virus infection in Mimika, Papua Province, Indonesia R. Herman* (Jakarta, Indonesia), A. Agustiningsih, H.D. Ikawati, A.A. Nugraha, V. Setiawaty P0458 A phase 1, multiple ascending dose study of AVI7288, a PMOplus™ compound with activity against Marburg virus A. Heald* (Bothell, United States), M. O’Connor, J.B. Saoud, E. Kaye, M. Al-Ibrahim 24th ECCMID / Barcelona Final Programme 153 Chairs, Speakers & Authors P0443 P0450 Exhibition The impact of dynamic clay system on infectious viruses M. Bellou* (Patras, Greece), V. Syngouna, S. Paparrodopoulos, A. Vantarakis, C. Chrysikopoulos General Information P0442 Posters Saturday, 10 May 2014 Poster Sessions Saturday, 10 May 2014 P0459 Evaluation of serum cytokines and adhesion molecules as prognostic factors in patients with Crimean-Congo haemorrhagic fever G. Canpolat, C. Ataman Hatipoglu* (Ankara, Turkey), C. Bulut, H. Uludag Altun, S. Kinikli, A. Demiröz 15:30 – 16:30 Poster Area POSTER SESSION I: Other viral infections P0465 Respiratory viral infections during 2013 in Evaggelismos General Hospital, GR: incidence and patterns of multiple virus co-infections E. Grispou* (Athens, Greece), E. Douka, V. Papastamopoulos, F. Veini, S. Kostourou, D. Tsimpouki, P. Karageorgou, K. Fountoulis, S. Zakynthinos, A. Skoutelis Hantavirus antibody seroprevalence in patients with chronic renal disease in Turkey D. Akduman, R. Sariismailoglu, I.O. Tekin, E. Hur, F. Kokturk, N. Piskin* (Zonguldak, Turkey), H. Aydemir, G. Celebi P0466 Respiratory viruses in hospitalised children with lower respiratory tract infections in Riyadh L. Skakni* (Riyadh, Saudi Arabia), R. Hasan, N. Al Ragi, H. Al Qudairy, J. Al Mutairy, E. Al Kafari, D.A. Al Shahrani, M. Al Shehri P0462 West Nile virus outbreak in Lombardia region, northern Italy, in summer 2013 F. Rovida* (Pavia, Italy), A. Sarasini, G. Campanini, E. Percivalle, A. Pan, S. Possenti, L. Manzini, F. Castelli, M. Gramegna, F. Baldanti P0467 The viral aetiology of acute lower respiratory tract infections in hospitalised children younger than 2 years at a university hospital in Istanbul, Turkey K. Midilli* (Istanbul, Turkey), M. Kuskucu, S. Ergin, A. Abdelkareem, Y. Camcioglu P0463 Simultaneous outbreak of dengue and chikungunya fever in Al Hodayda, Yemen G. Rezza* (Rome, Italy), G. El-Sawaf, G. Faggioni, F. Vescio, R. Al Ameri, G. Helaly, A. Pomponi, H. Qadi, M. Ciccozzi, F.R. Lista P0468 Clinical severity of rhinovirus/enterovirus compared to other respiratory viruses in children S. Asner* (Toronto, Canada), A. Petrich, J.S. Hamid, D. Mertz, S.E. Richardson, M. Smieja P0464 The rapid response for Middle East Respiratory Syndrome Coronavirus (MERS-CoV) detection in Indonesia V. Setiawaty* (Jakarta, Indonesia), H.A. Pawestri, N.K. Susilarini, E. Samoedro, B.R. Hapsari, G. Tallis, E.W. Wulandari, M. Sudomo, P. Multihartina, T.Y. Aditama P0469 Human rhinovirus molecular detection in respiratory tract infections: a retrospective study of 43 adults A. Brebion* (Clermont-Ferrand, France), C. Archimbaud, M. Chambon, A. Mirand, C. Regagnon, H. Peigue-Lafeuille, C. Henquell P0470 Cytomegalovirus (CMV) infection in nonimmunocompromised critically ill patients T. Al Musawi* (Al Khobar, Saudi Arabia), A. Khawaldeh, A. Ghoneim, M. Sabry, M. Aldarweesh P0471 Cytomegalovirus seroprevalence as a risk factor in acute respiratory distress syndrome D.S.Y. Ong* (Utrecht, The Netherlands), P.M.C. Klein Klouwenberg, F.M. Verduyn-Lunel, C. Spitoni, J.F. Frencken, B. Dekker, M.J. Schultz, M.J.M. Bonten, O.L. Cremer P0472 HSV-1 reactivation in mechanically ventilated patients shows standard kinetics regardless of worsening respiratory function S. Scheithauer* (Aachen, Germany), M. Kleines, L. Schmidt-Redemann, H. Schulze-Steinen, S. Lemmen, G. Marx, T. Schürholz P0460 Antibody responses and viral load in patients with with Crimean-Congo haemorhagic fever: a comprehensive analysis during the early stages of the infection Z. Kocak Tufan, K. Ergunay, C. Bulut* (Ankara, Turkey), A. Ozkul, S. Kinikli, A.P. Demiroz P0461 154 24th ECCMID / Barcelona Final Programme Poster Sessions Saturday, 10 May 2014 P0475 Usefulness of MRI in patients with remote history of a severe course of tick-borne encephalitis A. Moniuszko* (Bialystok, Poland), E. Tarasow, P. Czupryna, S. Pancewicz, S. Grygorczuk, M. Kondrusik, J. Zajkowska P0476 Can IL28B genotype predict herpes labialis’ recurrence among immunocompetent population? M. Spaziante* (Rome, Italy), E. Biliotti, C. Franchi, D. Palazzo, R. Esvan, C. Furlan, G. Iaiani, C. Marsiglia, L. Fontanelli-Sulekova, G. Taliani P0477 Herpes zoster in a tertiary-care teaching hospital in Turkey S. Alp Cavus, O. Eren Kutsoylu* (Izmir, Turkey), M. Celik, N. Yapar, V. Avkan-Oguz P0478 Phylodynamic characterisation of coxsackievirus B2 Y.Y. Shi* (Kaohsiung, Taiwan), Y.C. Huang, P.Y. Chu P0479 Detection of common viral genomes and immunohistological inflammatory markers in endomyocardial biopsies of patients with unexplained dilated cardiomyopathy F. Renois, Y. Nguyen, C. Boulagnon, F. Lesaffre, P. Fornes, D. Metz, L. Andreoletti* (Reims, France) P0480 Presence of human herpes virus-6 genomic sequence in DNA samples of patients with thyroid gland diseases S. Gravelsina* (Riga, Latvia), M. Cistjakovs, A. Sultanova, S. Chapenko, A. Roce, E. Cunskis, S. Roga, M. Murovska, Z. Nora-Krukle P0481 Cytokine gene polymorphisms and relationship with congenital cytomegalovirus (CMV) infection in newborns and mother-to-foetus CMV transmission B. Kasztelewicz* (Warsaw, Poland), J. Czech-Kowalska, M. Kornacka, K. Dzierzanowska-Fangrat P0483 Epstein-Barr virus reactivation as a prognostic factor in elderly immunocompetent bacteraemic patients I.G. Bae* (Jinju, Korea), D.Y. Chang, O.H. Cho, S.J. Kim Posters Detection of virus in aqueous humour samples from Hospital de la Princesa (Madrid, Spain) J. Martiáñez* (Madrid, Spain), E. Lomas, E. Gallego, P. Sánchez, A. Guiu, A. Correa, L. Cardeñoso Comparison of HHV-6 specific T-cell immunity in individuals with and without chromosomally integrated HHV-6 (CIHHV-6) V. Strenger* (Graz, Austria), S. Kayser, D. Lassner, M. Seidel, W. Schwinger, S.W. Aberle, G. Jahn, S. Jürgens, C. Urban, T. Feuchtinger Chairs, Speakers & Authors P0474 P0482 Exhibition Risk factors and outcome of virus-related ARDS in 249 patients from 28 ICUs in the period 2009-2013 B. Mariani, F. Rovida* (Pavia, Italy), A. Piralla, A. Muzzi, G.A. Iotti, A. Braschi, F. Baldanti 24th ECCMID / Barcelona Final Programme 155 General Information P0473 ESCMID WHO Observership in 2014 Visit the WHO Regional Office for Europe and learn about their programmes! A group of 10 observers (ESCMID members) are offered a 3 day programme at the WHO Regional Office for Europe, Division of Communicable Diseases, Health Security and Environment (DCE) in Copenhagen, Denmark. Date of Observership: 30 September –2 October 2014 Applications accepted from: 15 May 2014, 10:00 CET Selection: ‘First come, first served’, ensuring CM, ID, gender and country balance. To apply, visit the ESCMID website. Deadline for applications: 30 May 2014, 16:00 CET www.escmid.org/WHO_Observer www.euro.who.int RZ_Ins_WHO_02.04.2014.indd 1 02.04.14 11:33 ESCMID ECDC Observerships in 2014 Visit ECDC and learn about the organisation! A group of 10 observers (ESCMID members) are offered a 5 day programme at the European Centre for Disease Prevention and Control (ECDC) in Stockholm, Sweden. Date of Observership: 01–05 September 2014 Applications accepted from: 15 May 2014, 10:00 CET Selection: ‘first come, first served’ but ensuring CM, ID, gender and country balance. To apply, visit the ESCMID website. Deadline for applications: 30 May 2014, 16:00 CET www.escmid.org/ECDC_Observer www.ecdc.europa.eu RZ_Ins_ECDC_14.04.2014.indd 1 16.04.14 10:18 Poster Sessions Sunday, 11 May 2014 P0492 Evaluation of a new method for the rapid exclusion of suspected bacteraemia and fungaemia M. Crow* (Reading, United Kingdom), H. Bennett, M. Grover, M. Dryden P0493 Rapid screening of positive blood cultures and instant verification of B. fragilis carbapenemase activity using matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) Å. Johansson* (Växjö, Sweden), J. Soki, E. Nagy P0494 Direct identification of bacteria in positive blood cultures using MALDI-TOF MS C. Ostergaard* (Vejle, Denmark) POSTER SESSION II: Infective endocarditis, bacteraemia and sepsis P0484 Unique blood culture for diagnosis of bloodstream infections: a prospective multicentre study S. Dargere* (Caen, France), J.J. Parienti, P.E. Gancel, N. Smaiti, C. Loiez, L.M. Joly, L. Lemée, R. Verdon, R. Leclercq, V. Cattoir P0485 Impact of monitoring of blood volume in BD BACTEC™ FX blood culture system: virtual volume vs actual volume J. Chang* (Seoul, Korea), J. Park, S. Park, B. Choi, N. Yoon, H. Sung, M. Kim Validation of the module for blood volume monitoring on the BD EpiCenter™ system as a continuous quality improvement measure L. Coorevits* (Wevelgem, Belgium), A.M. Van den Abeele P0495 Rapid pathogen identification in blood cultures by means of short-incubation MALDI-TOF (SI-MALDI-TOF) A. Kalanti* (Helsinki, Finland), A. Oksaharju, K. Rantakokko-Jalava, P. Kuusela P0487 How to distinguish between contamination and true bloodstream infection? A prospective cohort study of over six thousand blood cultures V. Fihman* (Creteil, France), G. Barnaud, F. Magdoud, T. Billard-Pomares, V. Manceron, B. Mesples, J.D. Ricard, C. Branger P0496 Automatic identification of bacterial species in a polymicrobial sample by MALDI-TOF mass spectrometry P. Mahé* (Marcy-l’Étoile, France), M. Arsac, S. Chatellier, V. Monnin, N. Perrot, S. Mailler, V. Girard, B. Lacroix, A. Van Belkum, J.B. Veyrieras P0488 Value of direct examination of peripheral and catheter-drawn blood samples for the diagnosis of catheter-related bloodstream infection in intensive-care neonates M. Deleers* (Brussels, Belgium), M. Dodemont, B. Van Overmeire, Y. Hennequin, D. Vermeylen, S. Roisin, O. Denis P0497 Microbiological diagnosis in cardiac device infections: the role of sonication A. Oliva* (Rome, Italy), B.L. Nguyen, M.T. Mascellino, G. Riitano, A. Cipolla, A. D’Abramo, M. Iannetta, C.M. Mastroianni, V. Vullo P0498 Concordance between isolates from blood cultures, intraoperative tissue specimens and graft cultures (sonicates) in vascular graft infections T. Lejko-Zupanc* (Ljubljana, Slovenia), B. Kokozar - Ulcar, M. Logar, N. Lakic, S. Jeverica P0499 Increased length of stay and mortality attributed to hospital-acquired infections in a tertiary hospital; a 12-year prospective observational study A. Koch* (Bergen, Norway), R. Nilsen, R. Cox, S. Harthug P0500 Determinants of recourse to surgery in 998 infective endocarditis cases in France S. Sunder* (Tours, France), L. Guillon, C. Gaborit, E. Rusch, S. Baron, L. Bernard Rapid test for the detection of bloodstream infections R. Verma* (La Canada, United States), K. Zangwill, H. Lee, C. Yu, A. Ibrahim P0490 Assessing the turnaround time for organism identification in bloodstream infections by conventional microbiological method K.Y. Ng* (Hong Kong, China), P.Y. Law, M.K. Yan, V.C. Cheng, P.L. Ho P0491 Rapid and convenient direct identification of bacteria and yeast in positive blood culture by use of the VITEK® MS MALDI-TOF MS system S. Kawakami* (Tokyo, Japan), M. Asahara, Y. Atukawa, T. Hurukawa, N. Matsunaga, Y. Ono 24th ECCMID / Barcelona Final Programme Exhibition P0489 Posters P0486 Chairs, Speakers & Authors Poster Area 157 General Information 12:30 – 13:30 Poster Sessions Sunday, 11 May 2014 P0501 Infective endocarditis caused by toxigenic Corynebacterium diphtheriae M. Saule* (Riga, Latvia), A.O. Balode, T. Obidenova, P. Aldins, I. Jansone P0502 Preoperative assessment of factors associated with mortality after cardiac surgery for infective endocarditis S. Patrat-Delon* (Rennes, France), A. Rouxel, A. Gacouin, E. Flecher, O. Fouquet, Y. Le Tulzo, N. Lerolle, P. Tattevin, J.M. Tadie P0503 P0504 Infective endocarditis in Turkey: causative microorganisms, clinical features and analysis of risk factors for mortality in 325 cases S. Simsek Yavuz* (Istanbul, Turkey), A. Sensoy, H. Kasikçioglu, S. Ceken, D. Deniz, A. Yavuz, F. Koçak, K. Midilli, M. Eren, I. Yekeler Endocarditis by Enterococcus spp. diagnosed in the University Hospital Miguel Servet in Saragossa during the years 2011, 2012 and 2013 S. Ruiz Aliende* (Zaragoza, Spain), E. Lain Miranda, M.C. Villuendas Usón, M. Vidal García, M.J. Revillo Pinilla P0505 Analysis of Escherichia coli (EC) bloodstream infection (BSI) during a four-year period in a French general hospital S. Nguyen* (Tourcoing, France), S. Dekeyser, E. Beclin, F. Dufossez, E. Senneville, D. Descamps P0506 Predictors of third-generation cephalosporinresistant Enterobacteriaceae in the elderly with community-onset bloodstream infections C. Fehér* (Barcelona, Spain), C. Hernandez, N. Cobos, C. DeLaCalle, L. Morata, F. Marco, M. Almela, J. Mensa, A. Soriano, J.A. Martínez P0507 Predictors of Pseudomonas aeruginosa in the elderly with community-onset bloodstream infections C. Fehér* (Barcelona, Spain), C. Hernandez, N. Cobos, C. DeLaCalle, L. Morata, F. Marco, M. Ortega, J. Mensa, A. Soriano, J.A. Martínez P0508 P0509 158 Functional status and quality of life after community-acquired bacteraemia: a matched cohort study M. Dalager-Pedersen* (Aalborg, Denmark), R.W. Thomsen, H.C. Schønheyder, H. Nielsen The microbiology of severe sepsis M.L. Heginbothom* (Cardiff, United Kingdom), R.A. Howe, R. McArtney, M. Smithies, J. Parry-Jones, T. Szakmany 24th ECCMID / Barcelona Final Programme P0510 Mortality attributed to bacteraemia in an Andalusian secondary hospital. Study of prognostic factors A. Del Arco* (Marbella, Spain), A. Blázquez, J. De la Torre, N. Montiel-Quezel, J. Olalla, J.L. Prada, F. Rivas, M.V. Uribe, J. García Alegría, F. Fernández Sánchez P0511 Urosepsis in hospitalised urological patients: increasing rates in the multinational, multi-centre global prevalence of infections in urology (GPIU) study (2003 to 2011) Z. Tandogdu, M. Cek, M. Grabe, B. Wullt, P. Tenke, K. Naber, R. Pickard, R. Bartoletti, F. Wagenlehner* (Giessen, Germany), T. Bjerklund Johansen P0512 Multidrug-resistant bacteria and bacterial bloodstream infection among spinal cord injury & disorder (SCID) patients, severity and outcome: 15 years’ experience A. Dinh* (Paris, France), M. Saliba, I. Pierre, P. Denys, E. Ronco, C. Lawrence, B. Clair, C. Perronne, L. Bernard P0513 Results of an early intervention programme in patients with bacteraemia in a secondary hospital – epidemiological and evolutive characteristics A. Blazquez* (Marbella, Spain), A. Del Arco, J. De la Torre, J. Olalla, F. Fernández Sánchez, J.L. Prada, F. Rivas, M.V. Uribe, J. García Alegría, N. Montiel Quezel P0514 Bloodstream infections caused by anaerobes – aetiology and antibiotic susceptibility profile during a 3-year period at University Hospital for Infectious Diseases, Zagreb, Croatia S. Bukovski-Simonoski* (Zagreb, Croatia), T. Tot P0515 Eggerthella lenta bacteraemia: a retrospective case series B.J. Gardiner, A. Tai* (Melbourne, Australia), D. Kotsanas, S.A. Roberts, R. Junckerstorff, T.M. Korman P0516 Predictive value of biomarkers for death in sepsis A. Cioara* (Cluj-Napoca, Romania), J. Ten Oever, T. Crisan, I. Filipescu, M. Flonta, M. Netea, M. Lupse P0517 Procalcitonin fails to rule out bloodstream infection in patients with SIRS: a case-control study M. Hoenigl* (Graz, Austria), R.B. Raggam, J. Wagner, F. Prueller, J. Prattes, K. Seeber, E. Leitner, I. Zollner-Schwetz, A.J. Grisold, R. Krause Poster Sessions Sunday, 11 May 2014 P0520 P0521 P0522 P0523 P0524 Poster Area POSTER SESSION II: Molecular diagnosis of bloodstream infections P0526 Diagnosing bloodstream infection with broad range bacterial 16S rRNA PCR from whole blood: a new protocol using a CD64-guided diagnostic algorithm D. Stubljar, M. Skvarc* (Ljubljana, Slovenia), P. Rogina, T. Lejko, A. Kaasch P0527 Nationwide study on the use of endovascular catheters in internal medicine departments M. Guembe* (Madrid, Spain), M.J. Pérez Granda, J. Capdevila, J. Barberán, B. Pinilla, P. Martín-Rabadán, E. Bouza Multi-centre evaluation of Verigene® BC-GN test for rapid detection of Gram-negative bacteria from positive blood cultures from paediatric inpatients J. Mortensen* (Cincinnati, United States), B. DeBurger, N. Turner, S. Roundtree, C. Ventrola, D. BLecker-Shelly, K. Sullivan P0528 Pathogenesis and clinical outcome of peripheral line-associated bloodstream infections in Japan H. Kurai* (Shizuoka, Japan), I. Kawamura, N. Hosokawa, M. Abe, M. Kimura, Y. Ainoda, T. Fujita, N. Sekiya, N. Takeshita, N. Ohmagari Evaluation of FilmArray® blood culture system in bloodstream infections in a tertiary hospital L. Goterris Bonet* (Barcelona, Spain), M. Lung, Z. Moure, M.T. Martín, A. Rando, C. Gulín, T. Pumarola, A.M. Planes P0529 Outcome of subcutaneous injection port (SIP) infections in a cohort study: proposal of additional criteria for prompt removal M. Vidal* (Clermont Ferrand, France), N. Mrozek, J. Genillon, E. Forestier, S. Trouillier, B. Pereira, O. Lesens FilmArray® blood culture identification system (BCID); an integrated, fully automated sample processing/multiplex PCR for rapid identification of pathogens from positive blood culture bottles H. Salimnia* (Detroit, United States), P. Lephart, T. Painter, R. Mitchell, T. Burger, K. Kanack, M. Fairfax P0530 Efficacy of antibiotic-lock therapy in the treatment of infections related to long-term catheters in cancer patients K.Y. Ibrahim, T. Ferretti, M. Freire, A.E. Zerati, J.M. Leal Filho, P.H.X. Nabuco, P.M. Hoff, L.C. Pierrotti* (São Paulo, Brazil), E. Abdala Rapid identification of microorganisms in blood cultures applying the FilmArray® blood culture identification panel E. Leitner* (Graz, Austria), S. Klingsbigel, B. Neuhold, M. Hoenigl, R. Krause, G. Feierl, A. Grisold P0531 Comparison of the efficacy of SeptiFast (Roche) and FISH methods in detecting bacteria in whole blood of patients with sepsis T. Gosiewski* (Crakow, Poland), A. Flis, R. Drwila, A. Sroka, A. Kedzierska, A. Pietrzyk, M. Bulanda POSTER SESSION II: News on catheter-related bloodstream infections P0519 12:30 – 13:30 Unusual distribution of pathogens in a European multi-centre study about central venous catheter-related bloodstream infections T. Van Der Kooi* (Bilthoven, The Netherlands), M. Wolkewitz, B. Van Benthem, S. De Greeff, H. Grundmann, W. Zingg on behalf of the PROHIBIT study group Evaluation of catheter-related bloodstream infections in elderly patients undergoing haemodialysis S. Kose* (Izmir, Turkey), G. Ersan, B. Tatar, Y. Ulu, P. Adar 24th ECCMID / Barcelona Final Programme 159 Posters Poster Area Clinical characteristics, treatment and outcomes of methicillin-resistant Staphylococcus aureus (MRSA) catheter-related bacteraemia in haemodialysis patients G. Cuervo* (Barcelona, Spain), E. Shaw, O. Gasch, M. Camoez, M. Dominguez, B. Padilla, V. Pintado, J. Rodriguez-Baño, N. Benito, M. Pujol Chairs, Speakers & Authors 12:30 – 13:30 P0525 Exhibition Major impact over mortality of a sepsis code based on an early detection electronic algorithm, a standardised order set and a sepsis team approach P. Martin Rico* (Denia, Spain), A. Valdivia Perez, M.D. Marco Lattur, J. Chorda Ribelles, J.M. Lacalle Martinez, O. Esparcia Rodriguez, J. Cardona Pereto, A. Navarro Juanes, V. Moncho Mas, R. Sala Lopez General Information P0518 Poster Sessions Sunday, 11 May 2014 P0532 Multiplex RT-PCR for rapid diagnosis of bacteraemia in neutropenic febrile haematological patients J. Gomez* (El Prat De Llobregat, Spain), S. Diaz, A. Viu, E. Gimeno, L. Sorli, J.P. Horcajada, M. Salvado P0533 The Tm mapping method: a novel method that enables rapid identification of unknown pathogenic bacteria in sepsis within three hours of whole blood collection H. Niimi* (Toyama, Japan), T. Ueno, M. Mori, H. Tabata, H. Minami, M. Goto, S. Saito, I. Kitajima P0534 P0535 P0536 Development of a rapid molecular test for bacteria and Candida detection using large volume blood samples A. Bacconi* (Carlsbad, United States), G. Richmond, L. Blyn, R. Sampath, D.J. Ecker Establishing the potential for whole genome sequencing of Escherichia coli directly from positive blood culture media L.W. Anson* (Oxford, United Kingdom), L.J. Pankhurst, A. Votintseva, N. Stoesser, D. Crook Use of peptide nucleic acid fluorescence insitu hybridisation on blood cultures without antimicrobial stewardship (AS) intervention does not improve time to appropriate therapy E. Avdic* (Baltimore, United States), T. Wakefield, M. Gherna, E. Hadhazy, K. Carroll, S. Cosgrove P0537 Association between lower PaCO2 levels and true-positive blood cultures Y. Natori* (Tokyo, Japan), A. Mikami, G.A. Deshpande P0538 Quicker identification of Gram-positive cocci in clusters in patients with suspected sepsis C. Retz, S. Andersson, H. Enroth, L. Ljungström, D. Karlsson, A.K. Pernestig* (Skövde, Sweden) P0539 Pathogen identification from positive blood cultures using automated sample preparation and automated fluorescent in situ hybridisation (FISH) K. Hance, C. Michel, E. Allers, M. Mensack, E. Tuttle, S. Metzger* (Tucson, United States), C.S. Price, D. Howson 160 24th ECCMID / Barcelona Final Programme P0540 Multiplex detection of Gram-positive bacteria from blood culture with GenMark’s developmental sample-to-answer platform H. Liang, A. Marchese, S. Yousif, A. Maer, Y. Chen, L. Freeman-Cook, J. Hawkins* (San Diego, CA, United States) P0541 Potential impact of a microarray-based nucleic acid assay for the rapid detection of Gramnegative bacteria and resistance markers in positive blood cultures L. Infurnari* (Milan, Italy), N. Mancini, N. Ghidoli, A. Valzano, N. Clementi, R. Burioni, M. Clementi P0542 Rapid detection of extended-spectrum beta-lactamases, plasmid-mediated cephalosporinases (AmpC) and carbapenemases directly from blood cultures by use of a nucleic acid DNA microarray P. Pancholi* (Columbus, United States), R. Faubel, K. Thomas, D. Smith, J.M. Balada-Llasat P0543 Development and characterisation of a PCR/ESIMS assay capable of detecting and identifying diverse bacteria and Candida in whole blood M. Frinder* (Carlsbad, United States), D. Metzgar, H. Carolan, D. Toleno, R. Sampath, L. Blyn, D. Ecker, R. Rothman, S. Peterson, K. Carroll P0544 Routine microbiological screening of central venous catheters in haemato-oncological patients J. Wagner* (Graz, Austria), W. Duettmann, G. Theiler, P. Neumeister, I. Zollner-Schwetz, M. Hoenigl, T. Valentin, R. Krause P0545 Metabolites in blood for predicting bacteraemia in patients admitted to an infectious diseases clinic, a pilot study A. Kauppi, A. Edin, I. Ziegler, A. Gylfe, A. Sjöstedt, P. Mölling, K. Strålin, Å. Johansson* (Umea, Sweden) P0546 Comparison of PCR/ESI-MS with 16s rDNA PCR for the detection of microbial pathogens in heart valve samples D. Gascoyne-Binzi, M. Wilcox, J. Sandoe* (Skipton, United Kingdom) Poster Sessions P0547 Emerging superbugs: impact of active vs passive surveillance in detection of carbapenemresistant organisms – a single centre experience C. Akhoon* (London, United Kingdom), N. Desai, M. Graver, J. Philpott-Howard, A. Verma Epidemiology of carbapenemase-producing Klebsiella pneumoniae in a north-west Italian region: report from the regional surveillance system A. Rocchetti, C.M. Zotti, P.A. Argentero, R. Raso, A. Biglino, S. Livigni, S. Romagnoli, S. Corcione* (Turin, Italy), F.G. De Rosa, V. Ghisetti P0548 P0557 Performance and cost effectiveness of IDMsurveillance®, a software tool for automated detection of hospital-acquired infections I.A.M. Ten Seldam, H.R.A. Streefkerk, C. Van der Hoeven, R. Kamphuis, H.A. Verbrugh, A.W. Friedrich, J.L.V. Eriksson, N. Al Naiemi* (Hengelo, The Netherlands) The impact of carbapenemase-producing Enterobacteriaceae on overall intensive care unit mortality A.N. Wekesa* (Hilversum, The Netherlands), A. Antoniadou, M.J.D. Bonten, C. Brun-Buisson, M.J.D. Dautzenberg, L.P.G. Derde, H. Giamarellou, M. Gniadkowski, G.L. Petrikkos, O.B.O. MOSAR P0549 P0558 Lessons learned from a clonal OXA-48 outbreak: proactive rather than reactive surveillance better suits healthcare facilities where carbapenemresistant Enterobacteriaceae are endemic K. Marimuthu* (Singapore, Singapore), P. Krishnan, D. Lye, A. Chow, B. Ang P0550 P0559 Infection control policies and ICU-acquired ESBL-cases in Germany: a cross-sectional questionnaire survey of 224 ICUs F. Maechler* (Berlin, Germany), F. Schwab, C. Geffers, A. Gropmann, P. Gastmeier Surveillance of healthcare-associated outbreaks in Germany; comparison of outbreaks on nonpaediatric ICUs and neonatal and paediatric ICUs, 2012/2013 S. Haller* (Berlin, Germany), T. Eckmanns, M. Abu Sin P0551 P0560 Characterisation of carbapenem-resistant Enterobacteriaceae in China: a nationwide, retrospective, 9-year surveillance study Q. Yang* (Beijing, China), H. Duan, H. Zhang, H. Wang, M. Xiao, Y. Xu, M. Chen Seven-year surveillance of ESKAPE pathogens in culture-positive pneumonia – a hospital-based study A. Slavcovici* (Cluj-Napoca, Romania), A. Radulescu, N. Hagau P0552 P0561 Active surveillance for carbapenemase-producing Enterobacteriaceae (CRE) from 6/2011 to 6/2013 C. Wessels, D. Peter* (Cologne, Germany), S. Messler, F. Mattner P0553 P0562 Carbapenem-resistant Klebsiella pneumoniae: the role of rectal swab specimens in surveillance E. Sala* (San Fermo della Battaglia, Italy), R. Mauri, A. Genasetti, S. Armitano, S. Tettamanti, S. Campa, D. Santoro, G. Giana P0554 Healthcare-associated infections and antimicrobial use: results of the European point prevalence survey in Sicily, Italy A. Agodi, M. Barchitta* (Catania, Italy), R. Cunsolo, G. Murolo, V. Torregrossa, M.L. Moro Determining transmissibility of Klebsiella pneumoniae and Escherichia coli in European intensive care units using Raman spectroscopy M.J.D. Dautzenberg* (Utrecht, The Netherlands), L.P.G. Derde, C. Brun-Buisson, M. Gniadkowski, M.J.M. Bonten, On behalf the MOSAR WP3 study group Prediction of carriage with ESBL-producing bacteria at hospital admission; a cross-sectional study T. Platteel* (Utrecht, The Netherlands), J. Cohen Stuart, M. Leverstein-van Hall, S. Thijsen, E. Mascini, B. Van Hees, A. Fluit, M. Bonten Prevalence of ESBL-producing Enterobacteriaceae mother colonisation and mother-to-neonate transmission L. Lopez Cerero* (Seville, Spain), C. Jiménez, S. Luna, C. Vera, J. Rodríguez-Baño, A. Pascual 24th ECCMID / Barcelona Final Programme 161 Chairs, Speakers & Authors P0556 POSTER SESSION II: Surveillance of healthcare-associated infections Exhibition Emergence of NDM-1 enzyme in A. soli in Cuba: report from national surveillance programme (2010-2012) of Acinetobacter spp. D. Quiñones, I. Carvajal, Y. Pérez, M. Hart, J. Pérez, S. García, D. Salazar, R. Del Campo* (Madrid, Spain), S. Ghosh, N. Kobayashi Poster Area General Information P0555 12:30 – 13:30 Posters Sunday, 11 May 2014 Poster Sessions Sunday, 11 May 2014 P0563 Surveillance of ESBL-producing isolates in urine in the elderly during a period of 3 years (20112013) in Aveiro, Portugal S. Magalhaes, C. Brandao, S. Soares, E. Ramalheira, S. Ferreira* (Aveiro, Portugal) P0564 Cohort study on the prevalence and risk factors for ESBL/AmpCs at Dutch day care centres M. Koningstein* (Bilthoven, The Netherlands), M. Leenen, R. Zuidema, R. Ensering, K. Veldman, D. Mevius, W. Van Pelt P0566 Active surveillance and feedback in a renal dialysis network reduces infection rates S. Collier* (London, United Kingdom), H. Kandil, V. Pang, J. Cross, S. Hopkins P0567 A prospective community intervention trial to assess scabies and pyoderma prevalence in a highly endemic population L. Romani* (Sydney, Australia), J. Kaldor, H. Whitfeld, H. Wand, A. Steer 12:30 – 13:30 Poster Area P0572 Impact of comprehensive implementation strategy of practice guideline for central lineassociated bloodstream infection prevention: 12 months’ intervention results in 15 hospitals in Korea P.G. Choe, M.J. Shin, H.Y. Jin, Y.H. Choi, O.J. Choi, N.J. Park, K.H. Kim, S.H. Han, E.J. Choo, H.B. Kim* (Seongnam, Korea) P0573 Effectiveness of a bundle-intervention for reducing catheter-associated bacteriuria in two medical and surgical wards M. Gimenez* (Badalona, Spain), R. Raya, M. Ribas, M. Corral, N. Sopena, I. Casas, M. Barbera, L. Mateu, J. Areal, M. Caraballo P0574 Lower catheter failure and longer dwell time using a closed peripheral venous catheter system (CPVCS) without scheduled replacement: a quasiexperimental study A. Hornero* (Barcelona, Spain), R. Escofet, G. Cuervo, E. Shaw, E. Castillo, A. Baque, A. Palau, R. Solà, A. Fabregas, M. Pujol P0575 A strategy to reduce central line-associated bloodstream infections: external inspection of compliance with standards S. Cherifi* (Brussels, Belgium), S. Arias, J. Devriendt, D. De Bels, P. Gottignies, B. Byl P0576 Catheter-related bacteraemia prevention: the Spanish experience M. Palomar* (Lleida, Spain), F. Alvarez Lerma, Y. Yagra, P. Olaechea P0577 Individual prognostic impact of the components of a bundle related to Staphylococcus aureus bacteraemia clinical management L.E. Lopez-Cortes* (Seville, Spain), M.D. Del Toro, J. Gálvez-Acebal, E. Bereciartua-Bastarrica, M.C. Fariñas, M. Saenz-Franco, C. Natera, J.E. Corzo, A. Pascual, J. Rodríguez-Baño POSTER SESSION II: Targeting zero S. aureus and CVC-BSI P0568 Effect of contact precaution and cefazolinbased antimicrobial prophylaxis stewardship for preventing methicillin-resistant Staphylococcus aureus (MRSA) surgical site infections (SSI) in clean orthopaedic surgeries H. Kawamura* (Kagoshima, Japan), A. Shigemi, K. Matsumoto, T. Koriyama, M. Orita, S. Nagano, K. Setsuro, K. Tokuda, J. Nishi P0569 Decolonisation of Staphylococcus aureus carriers in arthroplasty surgery. Results of intervention study in Príncipe de Asturias Hospital J. Barbero* (Alcala de Henares, Spain), E. Montero, R. Agudo, M. García, A. Rebollar, A. Culebras, L. Pérez, L. Gete, J. López P0570 Strict infection control (IC) leads to low incidence of methicillin-resistant Staphylococcus aureus (MRSA) bloodstream infections over 20 years B. Lakatos* (Budapest, Hungary), R. Frei, A. Widmer, U.H.B.S. Infection Control Team P0571 Methicillin-sensitive Staphylococcus aureus (MSSA) bacteraemia in haemodialysis patients – using root cause analysis to define interventions I. Gupta* (Birmingham, United Kingdom), M. Holland, S. Powers, V. Suresh 162 24th ECCMID / Barcelona Final Programme Poster Sessions Sunday, 11 May 2014 P0586 POSTER SESSION II: Automation of diagnostics Multicenter Evaluation of the Rolling-bead Automated Inoculation Technology (bd Kiestra Inoqula Bt™) for Isolation of Bacterial Cultures A. Brivio, F. Arena, G. Babini* (Mascalucia, Italy), E. Cesari, L. Ferrari, G. Giuliani, G.M. Rossolini, B.D. Participants to the Italian BD Kiestra Workshop Tour P0580 Initial evaluation of an image analysis device for the screening of cultures from clinical specimens J. Glasson* (Adelaide, Australia), R. Hill, M. Summerford P0581 Combination of urine flow-cytometry (UF) and matrix-assisted laser desorption/ionizationtime of flight mass-spectrometry (MALDI-TOF MS) directly from urine specimens allows rapid identification of bacterial pathogens A. Egli* (Basel, Switzerland), G. Müller, D. Goldenberger, A. Regeniter, R. Frei, G. Bonkat P0582 Comparative evaluation of inoculation of urine samples with WASP and InoqulA™ utilising a 10 microlitre inoculum for each instrument J. Iversen, G. Stendal, C.M. Gerdes, C.H. Meyer, C.O. Andersen, N. Frimodt-Moller* (Hvidovre, Denmark) P0583 Evaluation and optimisation of the Sysmex UF1000i system for the screening of urinary tract infection in primary healthcare elderly patients G. Martín Gutiérrez* (Seville, Spain), A. Porras González, C. Martín-Pérez, J.A. Lepe Jiménez, J. Aznar Martín P0584 Automated quantitative screening for antibiotic-resistant bacteria S. Edberg* (Sarasota, FL, United States) P0585 IgG avidity test for diagnosis of toxoplasmosis: performance of a new fully automated system (Liaison® XL) V. Meroni* (Pavia, Italy), P. Lanzarini, A. Vola, M. Chiaretto, F. Genco 12:30 – 13:30 Poster Area POSTER SESSION II: Molecular diagnostic methods in bacteriology – miscellaneous P0587 Contribution of molecular methods to diagnostics of native joint infections T. Freiberger* (Brno, Czech Republic), B. Malisova, E. Nemcova, M. Cernochova, J. Novak, M. Filipovic, J. Jurankova P0588 Utility of the FilmArray® blood culture identification (BCID) panel for molecular diagnosis of infectious diseases from samples other than blood cultures M. Micó García* (Barcelona, Spain), F. Navarro, Y. González, A. Brell, C. López, D. De Miniac, F. Sánchez, B. Mirelis, P. Coll P0589 Spectrum of pathogens in surgically treated infective endocarditis patients with focus on fastidious and non-cultivable bacteria M. Cernochova* (Brno, Czech Republic), E. Nemcova, M. Vanerkova, H. Suranska, J. Pol, P. Nemec, T. Freiberger P0590 Underestimation of the number of different bacterial species in pleural infections’ cultures M. Kemp* (Odense, Denmark), K.H. Jensen, C.N. Meyer, T.R. Thomsen, O. Kommedal, R. Dargis, J.J. Christensen P0591 Intrapartum GBS screening in a delivery room with an on demand PCR: a feasibility study E. Van Elzakker* (The Hague, The Netherlands), S. Thijssen, S. Schoondermark-Stolk, C. Visser, A. Sprij, P. Ottervanger P0592 Group B streptococcal infections among adults in Iceland: 1978-2012 surveillance E.S. Björnsdóttir* (Reykjavik, Iceland), E.R. Ferreira Martins, H. Erlendsdóttir, G. Haraldsson, J. Melo-Cristino, M. Ramirez, K.G. Kristinsson P0593 Comparison between phenotypic and genotypic methods for the identification of the Streptococcus anginosus group R. Arinto-Garcia* (Lisbon, Portugal), M.D. Pinho, M. Ramirez, J. Melo-Cristino 24th ECCMID / Barcelona Final Programme 163 Posters P0579 Validation of optimal sample volume/loop/ streaking/pattern and flexibility to customise solutions for Walk-Away Specimen Processor (WASP) users R. Botrugno* (Brescia, Italy), G. Catalano, L. Conter, P. Valzelli, S. Castriciano Chairs, Speakers & Authors P0578 Mining clinically relevant signatures from colony morphology images A.M. Sousa* (Braga, Portugal), M.O. Pereira, A. Lourenço Exhibition Poster Area General Information 12:30 – 13:30 Poster Sessions Sunday, 11 May 2014 P0594 Development of a real-time LAMP assay for the detection of group B Streptococcus in pregnant women L. O’Connor* (Galway, Ireland), C. Mullin, E. Keady, S. Lahiff, B. Glynn, T.J. Smith P0595 The epidemiology of group B Streptococcus bloodstream infection: a multi-national population-based assessment of its incidence in neonates and adults M. Ballard* (Calgary, Canada), H. Schønheyder, J. Knudsen, O. Lyytikäinen, M. Dryden, K. Karina, L. Valiquette, M. Pinholt, K. Laupland P0596 P0597 P0598 Comparison between culture and a helicasedependent amplification method for the detection of group B Streptococcus T. Marti* (Marshfield, United States), K. Flavin, B. Olson, T. Novicki, T. Uphoff Detection of vancomycin-resistant enterococci (VRE) by loop-mediated isothermal amplification (LAMP): a rapid, simple and cost-effective alternative to PCR P. Jayaratne* (Hamilton, Canada), L. Monkman Improving the routine identification of Aeromonas species by a novel multiplex PCR K.E.P. Olsen* (Copenhagen, Denmark), S. Persson, J.N. Jensen P0599 DNA-based assay for detailed pathogen characterisation I. Barisic* (Vienna, Austria), J. Petzka, S. Schoenthaler, H. Wiesinger-Mayr P0600 Evaluation of the RIDA®GENE Bordetella realtime PCR assay for the laboratory diagnosis of Bordetella infections L. Kastl* (Darmstadt, Germany), A. Simons, A. Veldenzer, U. Eigner, M. Holfelder P0601 P0602 164 Are PCR and single IgG measurement in convalescent serum complementary for the diagnosis of an acute B. pertussis infection? K. Loens* (Antwerp, Belgium), K. Huygen, T. Verheij, J. Teepe, C. Lammens, H. Goossens, M. Ieven Identification by 16S rRNA gene sequencing defines new species and clarifies pathogenicity of Haemophilus spp. recovered from the genitourinary tract of adult males J. Clarridge* (Seattle, United States) 24th ECCMID / Barcelona Final Programme P0603 Clinical spectrum and molecular characteristics of Klebsiella pneumoniae causing invasive infections M. Basma* (Sfax, Tunisia), A. Hammami P0604 Detection and distribution of virulence genes in clinical isolates of Aeromonas spp. M. Marzouk, H. Bargui, A. Ferjani, N. Hannachi, M. Haj ali, J. Boukadida* (Sousse, Tunisia) P0605 Development of multiplex real-time PCR assay for detection of Acinetobacter baumannii, Pseudomonas aeruginosa, Klebsiella pneumoniae and Escherichia coli J.A. Savochkina* (Moscow, Russia), I.A. Alexandrova, A.E. Guschin, G.A. Shipulin P0606 Long-term storage of clinical samples in CyMol® medium for fluorescence in situ hybridisation (FISH) and culturing from the ESwab™ system L. Larsen, Y. Xu, M. Pedersen, H. Schønheyder* (Aalborg, Denmark), T. Thomsen P0607 Detection of Streptococcus tigurinus in the human oral microbial flora by a specific 16S rRNA gene real-time PCR A. Zbinden* (Zurich, Switzerland), F. Aras, G.V. Bloemberg, P. Schmidlin, N. Bostanci P0608 Prevalence of Streptococcus gallolyticus in tumours and matched normal mucosa in an unselected cohort of CRC patients A. Galiana* (Elche, Spain), M. Andrés, V. Sánchez-Hellín, P. López-García, M. Ruiz-García, M.I. Castillejo, A. Castillejo, V.M. Barberá, J.L. Soto, G. Royo P0609 Identification of Nocardia species by RFLP with sodA gene K. Sánchez-Herrera, H. Sandoval Trujillo, A. Couble, D. Mouniée, N. Ramírez-Durán, M. Uzcategui de Morillo, J.A. Serrano, E. Bergeron, P. Boiron, V. Rodriguez Nava* (Lyon, France) P0610 Molecular identification and susceptibilities of Nocardia clinical strains F. Kontos, A. Argiropoulou, G.S. Christodoulatos, E. Trikka-Graphakos, V. Liakou, V. Baca, S. Lyroni, K. Tsiveriotis, K. Paraskevi, L. Zerva* (Athens, Greece) P0611 The mystery of a presumably saprophytic strain of Leptospira sp. Bairam-Ali M.S. Kunda* (Moscow, Russia, O.L. Voronina, E.I. Aksenova, A.N. Semenov, E.M. Petrov, V.G. Lunin, Y.U.V. Ananyina, A.L. Gintsburg) Poster Sessions Sunday, 11 May 2014 P0614 Molecular approaches to the diagnosis of ocular infectious diseases K. Ohkusu* (Gifu, Japan), K. Mochizuki, T. Ezaki P0615 A rapid and innovative molecular detection platform for the identification of pathogens in severe infections J. Gutierrez* (Carlsbad, United States), J. Fillman, S. Thorson, G. Liaw, R. Warren, J. Drader, J. McCoy P0616 Importance of in silico control of primers and probes in clinical molecular diagnosis A. Wicky* (Lausanne, Switzerland), R. Brouillet, R. Sahli, P. Meylan, P.M. Hauser, A. Telenti, G. Greub, K. Jaton P0617 Review of 16S and its direct sequencing results for clinical specimens submitted to a reference laboratory M. Payne* (Vancouver, Canada), L. Hoang P0618 An approach towards a standardised microbiological sampling protocol in forensic pathology A. Fernández-Rodríguez* (Madrid, Spain), V. Saegeman, J. Lucena, W. Van De Voorde, A. Angelini, N. Ziyade, N. Elgörmüs, G. Yagmur, P.M. Garamendi, M.C. Cohen POSTER SESSION II: Point-of-care tests P0620 Evaluating the accuracy of a point-of-care immunoassay to identify viral and/or bacterial immune response in patients with acute febrile respiratory infection R. Sambursky* (Sarasota, FL, United States), N. Shapiro, M. Machin, W. Hooker, T. Phillips, P. Condon P0621 Evaluation of the SD Bioline test for the detection of Legionella serogroup 1 antigen in urine samples E. Heylen, E. De Witte, K. Loens, C. Lammens, J. Almirall, H. Goossens, G. Ieven* (Antwerp, Belgium) P0622 Evaluation of the Sofia Legionella FIA in comparison with the BinaxNOW® Legionella Urinary Antigen Card in two national reference centres A. Freydiere* (Bron, France), K. Gervasoni, G. Descours, V. Gaia, G. Lina, F. Vandenesch, S. Jarraud P0623 Repositioning of rapid antigen detection tests (RADT) for the diagnosis of invasive group A streptococcal infections V. Gazzano* (Bron, France), A. Berger, Y. Benito, A.M. Freydière, A. Tristan, S. Boisset, A. Carricajo, C. Poyart, F. Vandenesch, G. Descours P0624 Detection of Streptococcus pneumoniae in patients with bacteraemia using a new pneumococcal urinary antigen test (Uni-Gold™ S. pneumoniae) and other pneumococcal rapid tests H.B. Eriksen, M. Schei Haugan, S. Otte, N. Frimodt-Møller, J. Dahl Knudsen* (Hvidovre, Denmark) P0625 Fast measurement of staphylococcal cell wall proteins and exotoxins from culture material using antibody microarrays and fluorescence staining R. Ehricht, E. Müller, B. Stieber, V. Baier, D. Weicherding, J. Buechler, S. Monecke* (Dresden, Germany) P0626 The Unyvero™ implant and tissue infection cartridge – a rapid test to detect challenging pathogens H. Motejadded* (Holzgerlingen, Germany), S. Barth, M. Klein, K. Schwarzer, G.H. Luedke 24th ECCMID / Barcelona Final Programme Posters Massive diversification and mutants’ emergence in E. coli colonies living in an open environment C. Saint-Ruf* (Paris, France), P. Francino, G. D’Auria, I. Matic Poster Area 165 Chairs, Speakers & Authors P0613 12:30 – 13:30 Exhibition Molecular investigation of an hospital outbreak caused by multidrug-resistant Klebsiella pneumoniae A. Colombo* (Varese, Italy), R. Onori, G. Cassani, P. Grossi, A. Tebini, G. Minoja, D. Sassera, C. Bandi, T. Giani, A. Toniolo General Information P0612 Poster Sessions Sunday, 11 May 2014 P0635 Gnathostomiasis: a 10-year experience at King Chulalongkorn Memorial Hospital, Thailand O. Dhissayakamol* (Bangkok, Thailand), P. Siriyasatien, C. Suankratay The role of recombinant antigens in the serodiagnosis of human cystic echinococcosis A. Hernández-González, M. Mariconti, V. Meroni, L. Piccoli, E. Brunetti, J.M. Delgado, J. Rojas González, M. Stojkovic, T. Junghanss, M. Siles-Lucas* (Salamanca, Spain) P0636 Investigation of Toxocara canis IgG seropositivity and risk factors in patients with chronic urticaria B. Selek, O. Baylan* (Istanbul, Turkey), A. Kutlu, N. Ozaydin, M. Ozyurt The Italian registry of cystic echinococcosis F. Tamarozzi, P. Rossi, F. Galati, M. Mariconti, F. Rinaldi* (Pavia, Italy), G.J. Nicoletti, E. Pozio, E. Brunetti P0637 Seroprevalence of Echinococcus granulosus infection in Croatian patients with cystic liver disease M. Sviben, S. Ljubin-Sternak, T. Vilibic-Cavlek, T. Mestrovic* (Samobor, Croatia), G. Mlinaric-Galinovic P0638 Giant pulmonary hydatid cysts in a child E. Tasci, S. Dogan Kaya, S. Menekse Yilmaz* (Istanbul, Turkey) P0639 Multiple lung hydatidosis with pulmonary artery localisations S. Menekse Yilmaz* (Istanbul, Turkey), S. Deniz, S. Sahin, S. Dogan Kaya, E. Tasci 12:30 – 13:30 Poster Area POSTER SESSION II: Helminths P0627 P0628 P0629 P0630 Has dracunculiasis been completely eradicated in Australia? A recent surgical experience with the waterborne disease in Melbourne M. Pereira E Cotta* (Fitzroy, Australia), H. Sheorey, W. Morrison, J. Darby Seroprevalence and geographical distribution of chronic strongyloidiasis in an immigrant population in Spain A. Morilla, J.A. Boga, P. Martinez, M. Rodriguez, J. Fernandez, S. Rojo, F. Vazquez, A. Rodriguez-Guardado* (Oviedo, Spain) P0631 Strongyloidiasis and viral co-infection in immigrants in a Portuguese hospital R. Tavares* (Ereira, Portugal), J. Torres, P. Rodrigues, H. Oliveira, L. Glória, V. Rodrigues, I. Galvão, A. Messias, M. Cravo P0640 Improved serodiagnosis of human fascioliasis using recombinant saposin-like protein 2 from Fasciola hepatica B. Gottstein* (Berne, Switzerland), G. Boubaker, B. Merkle, M. Spiliotis, N. Müller, M. Doherr P0632 Retinitis and eosinophilic meningitis due to Angiostrogylus cantonensis treated with pan retinal photocoagulation and steroid E. Thiansukhon* (Udon Thani, Thailand), R. Pongsamart, N. Smitasin P0641 Detection of IL-4 after specific whole blood stimulation to diagnose and monitor cystic echinococcosis disease L. Petrone, V. Vanini, E. Petruccioli, G.M. Ettorre, E. Busi-Rizzi, V. Schininà, M.A. Gomez Morales, E. Pozio, A. Teggi, D. Goletti* (Rome, Italy) P0633 Ocular larva migrans – an underestimated disease P. Mihailescu* (Bucharest, Romania), L. Voinea, I. Ceaus, C. Istrate, C.-M. Cretu P0642 P0634 Dirofilaria repens in humans – an emerging anthropozoonosis in a Central European country (Romania): case-series A. Rascanu* (Bucharest, Romania), C. Chiotan, R.M. Hrisca, V. Gheorghita, C. Constantin, B. Bacescu, R. Moroti In vitro and in vivo investigations to develop functional imaging by positron emission tomography (PET) for murine and human alveolar echinococcosis B. Gottstein* (Berne, Switzerland), J. Wang, C. Porot, J. Knapp, O. Blagosklonov, D. Vuitton, S. Germain, Y. Seimbille, D. Camporese, C. Bordier 166 24th ECCMID / Barcelona Final Programme Poster Sessions P0651 Giardia intestinalis and faecal microbiota of patients from Ivory Coast V. Totino* (Rome, Italy), V. Iebba, F. Santangelo, D. Di Cave, F. Berrilli, R. D’Alfonso, S. Schippa P0652 Giardia lamblia triggers NF-kappaB cleavage and suppresses LPS-induced pro-inflammatory response in macrophages C.P. Faria, A. Silva, J.D. Martins, M.T. Cruz, S. Pereira, G.M. Zanini, M. Sousa* (Coimbra, Portugal) P0653 Intestinal parasites and anaemia in Piaroa Amerindians of the Venezuelan Amazonia C. Rivas Nuñez* (Caracas, Venezuela), C. Navarro Ocando, D. Santander, G. Navas, G. Coronado, A. Rodriguez, G. Gottberg, Z. Cordero, M. Uribe, L. Pocaterra P0654 Genetic characterisation of cryptosporidia in patients with haematological malignancies and human immunodeficiency virus infection P. Ranjan* (Lucknow, India), U. Ghoshal, A. Dey, V. Agarwal, S. Nityanand, U.C. Ghoshal P0655 Five-year review – intestinal parasite detection in patients treated at the University Hospital for Infectious Diseases, Zagreb, Croatia from 2008 to 2012 S. Bukovski* (Zagreb, Croatia), J. Lozic, D. Lukas, J. Granic Detection and genetic characterisation of Cryptosporidium in renal transplant recipients by real-time PCR and melting curve analysis A. Dey* (Lucknow, India), U. Ghoshal, P. Ranjan, U.C. Ghoshal, R.K. Sharma P0656 Bacterial and protozoal intestinal associations of patients with Blastocystis invasion A. Sigidaev* (St. Petersburg, Russia), E. Tarasova, M. Suvorova, V. Turitsin, S. Kozlov, K. Zhdanov, S. Zakharenko To compare the efficacy of percutaneous needle aspiration with percutaneous catheter drainage in the treatment of amoebiac liver abscess K. Singh* (New Delhi, India), A. Gogia, A. Gupta, S.P. Byotra P0657 High prevalence of Blastocystis in irritable bowel syndrome patients is associated with changes in gut microbiota composition; a case-control study C. Nourrisson, J. Scanzi, C. Nkoud Mongo, I. Wawrzyniak, B. Pereira, E. Viscogliosi, F. Delbac, V. Livrelli, M. Dapoigny, P. Poirier* (Clermont Ferrand, France) P0658 Intestinal parasites and anaemia in Jivi Amerindians of the Venezuelan Amazonia C. Navarro, C. Rivas Nuñez* (Caracas, Venezuela), G. Gottberg, A. Coronado, G. Navas, A. Rodriguez, Z. Cordero, M. Uribe, D. Santander, L. Pocaterra POSTER SESSION II: Intestinal parasites P0643 P0644 P0645 P0646 P0647 P0648 P0649 Two years of seasonal increase of Cryptosporidium in the The Netherlands but different subtypes: the importance of molecular typing J.H. Roelfsema* (Bilthoven, The Netherlands), H. Sprong, B. Schimmer, J.A. Sane, S.M. Cacciò, W. Van Pelt, J.W.B. Van der Giessen, L.M. Kortbeek Peridomestic rodents from Cape Verde as reservoirs of zoonotic genotypes of Giardia duodenalis A. Fernandez Alvarez* (San Cristóbal De La Laguna, Spain), I. Guillama, M. Barbosa, H. Spencer da Costa Lima, M. Djata, C. Feliu, B. Valladares, P. Foronda Enteric parasites in high-prevalence settings – a challenge for the diagnostic routine? H. Frickmann, N.G. Schwarz, J.N. Heriniaina, N. Randriamampionona, T. Razafindrabe, J.P. Rakotondrainiarivelo, R. Rakotozandrindrainy, J. May, R.M. Hagen* (Hamburg, Germany) A survey of intestinal parasites and commensals, and associated risk factors in humans, animals, water, and soil in Panama N.R. Sandoval, N. Rios, A. Mena, R. Fernández, M. Perea, R. Manzano-Román, J. Ruiz Santa-Quiteria, A. Hernández-Gonzalez, M. Siles-Lucas* (Salamanca, Spain) 24th ECCMID / Barcelona Final Programme 167 Chairs, Speakers & Authors Public health significance of Giardia duodenalis in livestock in the Ismailia Canal zone of Egypt: epidemiology and molecular analysis Y.A. Helmy* (Berlin, Germany), C. Klotz, J. Krücken, K. Nöckler, G. Von Samson-Himmelstjerna, K.-H. Zessin, T. Aebischer First report of Crypstosporidium in rodents from Santiago (Cape Verde) and the possible role in the transmission of zoonotic genotypes A. Fernandez Alvarez* (San Cristóbal De La Laguna, Spain), I. Guillama, M. Barbosa, H. Spencer da Costa Lima, M. Djata, C. Feliu, B. Valladares, P. Foronda Exhibition P0650 General Information Poster Area 12:30 – 13:30 Posters Sunday, 11 May 2014 Poster Sessions Sunday, 11 May 2014 P0659 History of antimicrobial use and the risk of Dientamoeba fragilis carriage D. Röser* (Copenhagen, Denmark), J. Simonsen, H.V. Nielsen, C.R. Stensvold, K. Mølbak P0660 The role of colonic antimicrobial peptides in human Blastocystis infections J.A. Yason* (Singapore, Singapore), K.S.W. Tan P0661 Amoebic liver abscess: a 10-year experience at King Chulalongkorn Memorial Hospital, Thailand P. Mahaparn* (Bangkok, Thailand), P. Siriyasatien, C. Suankratay P0662 Isolation and molecular identification of free living amoeba from diverse environmental resources of Pakistan A. Matin* (Haripur, Pakistan), T. Tanveer, A. Hameed, A. Akbar, A. Gul P0663 Protozoan-associated diarrhoeal infections in Portuguese patients M. Oleastro* (Lisbon, Portugal), A. Santos, I. Costa, S. Ferreira, A. Rodrigues, C. Júlio P0664 T. vaginalis in dry vaginal swabs: TMB TV assay run in the open channel of the Roche Z480 versus the GMT Presto plus assay in the Roche LightCycler® 480 II S.A. Morré* (Amsterdam, The Netherlands), D.J. De Waaij, J.H. Dubbink, H. Struthers, J.A. McIntyre, S. Ouburg, R.P.H. Peters 12:30 – 13:30 Poster Area P0667 Immunosuppression as a risk factor for the development of visceral leishmaniasis: a changing cohort at the Hospital for Tropical Diseases, London K. Fletcher, R. Issa* (London, United Kingdom), D. Lockwood P0668 Leishmaniasis in Turkey : cases of visceral leishmaniasis caused by Leishmania tropica M.E. Limoncu* (Manisa, Turkey), A. Ozbilgin P0669 MALDI-TOF mass spectrometry for the research of specific biomarkers of Leishmania infection by analysing strains isolated from biological samples A. Calderaro* (Parma, Italy), M. Piergianni, C. Gorrini, G. Piccolo, M. Buttrini, S. Montecchini, M.C. Medici, M.C. Arcangeletti, C. Chezzi, F. De Conto P0670 Congenital visceral leishmaniasis: a case report M. Gonzalez Sanz* (London, United Kingdom), S. Gomes, A. Kumar Dsa, K. Ritmeijer P0671 Demonstration of Leishmania spp. by nested PCR in stray cats of Izmir located in western Turkey H. Can* (Izmir, Turkey), M. Doskaya, G. Ozdemir, A. Caner, E. Atalay, B. Pektas, S. Gulce Iz, A. Degirmenci Doskaya, C. Un, Y. Guruz P0672 Leishmaniasis in Turkey: emerging Leishmania major infections in Anatolia A. Ozbilgin* (Istanbul, Turkey), G. Culha, S. Uzun, M. Harman, S. Gunasti Topal, F. Okudan, C. Gunduz, F. Bastien, F. Pratlong, O. Kurt P0673 Determination of the species of the sand flies – the vector of cutaneous leishmaniasis that is endemic in Mersin M.E. Limoncu* (Manisa, Turkey), I.C. Balcioglu, Y. Ozbel, S. Ozensoy Toz, S. Demir, H. Kavur, O. Ermis P0674 Leishmanicidal activity of novel biurets against L. tropica promastigotes: in silico and in vitro comparative study S. Khademvatan* (Ahvaz, Iran), A. Eskandari, N. Adibpour, F. Rahim P0675 Activity of antiretroviral drugs on Leishmania infantum: synergistic effects with essential oils S. Costa* (Coimbra, Portugal), R. Varandas, M. Machado, C. Cavadas, L. Salgueiro, C. Cavaleiro, M. Sousa POSTER SESSION II: Leishmania and Trypanosoma P0665 P0666 168 The evolution of the Leishmania donovani complex illustrated from an integrative and genomic perspective assessed with 845 strains O. Stark* (Berlin, Germany), B. Moser, H. Imamura, J. Cotton, T. Downing, T. Wirth, G. Schönian Toll-like receptor 9 polymorphism in Cretan patients with Leishmania infantum infection I. Messaritakis, G. Samonis, M. Antoniou, A. Andrianaki, J. Papadakis, M. Zacharioudaki, E. Pediaditis, M. Plataki, E. Galanakis, D. Kofteridis* (Heraklion, Greece) 24th ECCMID / Barcelona Final Programme Poster Sessions Sunday, 11 May 2014 P0678 P0679 P0680 P0681 P0682 P0683 P0684 Early detection of L. siamensis DNA in saliva of HIV-infected patients A. Phumee* (Bangkok, Thailand), U. Thavara, A. Tawatsin, S. Chusri, T. Hortiwakul, K. Silpapojakul, P. Siriyasatien 12:30 – 13:30 Poster Area POSTER SESSION II: Toxoplasmosis P0686 Changing epidemiology of toxoplasmosis in pregnant women from the highland region of Scotland R. Evans* (Inverness, United Kingdom), J. Chatterton, R. Milner, E. Watson P0687 Acute primary toxoplasmosis in travellers returning from Gabon N. Katanic* (Belgrade, Serbia), L. Lavadinovic, M. Pavlovic, K. Bojovic, I. Milosevic, J. Aritonovic Pribakovic, E. Gvozdenovic, O. Dulovic, A. Odalovic, Z. Dakic P0688 Risk factors for Toxoplasma gondii infection in women of childbearing age in the territory of northern Kosovska Mitrovica J. Aritonovic Pribakovic* (Kosovska Mitrovica, Serbia), N. Katanic, R. Katanic, A. Ilic, V. Minic, A. Mladenovic P0689 Detection of antibodies to Trypanosoma cruzi (T. cruzi) in human serum/plasma with a new fully automated assay, Liaison® XL Murex Chagas M. De Luca, M. Calleri, D. Santelia* (Saluggia, Italy), L. Pallavicini A 5-year study of Toxoplasma gondii infection in adults, children and pregnant women in northwestern Greece E. Nita, C. Boboyianni, C. Gartzonika, P. Karagianni, M. Papassava, S. Giannopoulos, S. Levidiotou* (Ioannina, Greece) P0690 Screening for Trypanosoma cruzi antibodies by using three immunological assays in migrants to Italy coming from endemic areas R. Grande* (Milan, Italy), D. Mileto, L. Galimberti, S. Antinori, S. Garelli, M.R. Gismondo, M. Galli Comparison of serological and molecular diagnosis of cerebral toxoplasmosis in blood and cerebrospinal fluid in HIV-infected patients H. Berredjem* (Annaba, Algeria), M. BenLaifa, I. Becheker, R. Bardi, K. Ayed P0691 Preliminary analysis of monosaccharides in virulent T. gondii Ankara and Ege-1 strains by CAP LC-ESI-MS/MS U. Sahar* (Izmir, Turkey), M. Doskaya, A. Caner, H. Can, E. Atalay, A. Degirmenci Doskaya, R. Deveci, Y. Guruz Evaluation of the new BIO-FLASH® Chagas assay on Biokit’s BIO-FLASH® analyser L. Taberner* (Lliçà d’Amunt, Spain), N. López, B. Canela, M. López, C. Hervás, L. Heredia Evaluation in Brazil of the new BIO-FLASH® Chagas assay on Biokit’s BIO-FLASH® analyser S. Faraudo* (Lliçà d’Amunt, Spain), N. Lopez, B. Canela, A. Guimaraes, A. Saez-Alquezar Sensitivity and specificity of Liaison® XL Murex Chagas assay for diagnosis of the Trypanosoma cruzi infection in non-endemic area (Spain) M. Flores-Chavez* (Madrid, Spain), I. Vasquez-Dominguez, M. Hernandez, T. Garate, J. Nieto Effects of Lavandula luisieri and Cymbopogon citratus on Trypanosoma brucei brucei: antiproliferative activity through cell cycle arrest at the G0/G1 phase S. Costa* (Coimbra, Portugal), C. Cavadas, C. Cavaleiro, L. Salgueiro, M.C. Sousa 24th ECCMID / Barcelona Final Programme 169 Posters First report of autochthonous leishmaniasis caused by Leishmania siamensis in Myanmar: case series N. Noppakun, A. Phumee, U. Thavara, A. Tawatsin, P. Siriyasatien* (Bangkok, Thailand) Discovery of new therapeutics to combat Trypanosoma cruzi infection and prevent Chagas disease L.M. Podust* (San Francisco, United States), D.F. Vieira, J.Y. Choi, C.M. Calvet, D. Kellar, J.L. Siqueira-Neto, J. Gut, J.H. McKerrow, W.R. Roush Chairs, Speakers & Authors P0677 P0685 Exhibition Galactofuranose synthesis: an innovative therapeutic target present in several species and stages of Leishmania S. Belaz* (Rennes, France), J.P. Gangneux, P. Lafite, R. Daniellou, F. Robert-Gangneux General Information P0676 Poster Sessions Sunday, 11 May 2014 Poster Area P0700 Assessment of travel health services; situation in Turkey between the years 2011-2013 G. Okay* (Istanbul, Turkey), T. Ozcan, S. Güler, H. Hatipoglu Stable populations of sandflies (Phlebotominae) in eastern Austria: a comparison of the trapping seasons 2012/2013 W. Poeppl, A.G. Obwaller, T.J. Naucke, G. Mooseder, H. Aspöck, J. Walochnik, H. Burgmann* (Vienna, Austria) P0701 Neuropathic pain in old leprosy patients J.M. Ramos* (Alicante, Spain), B. Alonso Castañeda, D. Eshetu, D. Lemma, F. Reyes, R. Belinchón, M. Gorgolas P0702 Brucellosis complications; 15 years’ experience H. Gul, C. Artuk, A. Karakas, G. Mert, O. Coskun* (Ankara, Turkey), C. Eyigün P0703 Clinical and epidemiological findings of tetanus in Georgia T. Tkhilaishvili, M. Javakhadze* (Tbilisi, Georgia), D. Kikabidze 12:30 – 13:30 POSTER SESSION II: Travel, tropical and parasitic diseases P0692 P0693 P0694 Birds as vectors of various human pathogenic parasites S. Petersdorf* (Düsseldorf, Germany), F. Gestmann, C. MacKenzie, K. Pfeffer, H. Mehlhorn Transfusion transmissable infections in South Sudan: cross-sectional study of human immunodeficiency virus (HIV), hepatitis B and C and syphilis prevalence among potential blood donors at Juba teaching hospital R. Wake* (London, United Kingdom), S. Williams, K. De Polnay, P. Gillet P0695 Clostridium difficile-associated diarrhoea in travellers: experience from a tropical medical unit in Spain A. Sarria* (Madrid, Spain), P. Trevisi, A. Arroyo, A. Enriquez, S. Puente, G. Ramirez, C. Toro P0696 Knowledge, attitudes and practices of Romanian international travellers I. Niculescu* (Bucharest, Romania), A. Hristea, R. Jipa, R. Petre, R. Moroti, C. Popescu, V. Arama, A. Streinu-Cercel P0697 P0698 P0699 170 Antibiotic susceptibility of diarrhoeagenic Escherichia coli strains in patients with traveller’s diarrhoea N. Iglesias Nunez* (Madrid, Spain), A. Arroyo Fajardo, P. Trevisi, B. López Quintana, A. Sarría Visa, C. Ladrón de Guevara, C. Toro Rueda Primary amoebic meningoencephalitis vs acute bacterial meningitis: a comparison of clinical presentations S.F. Mahmood* (Karachi, Pakistan), M.F. Zahid, M.H.S. Shaukat, B. Ahmed Cutaneous anthrax in southeast Anatolia, Turkey R. Tekin* (Diyarbakir, Turkey), B. Sula, O. Deveci, A. Tekin, F. Bozkurt, S. Kaya, M. Bekcibasi, S. Hosoglu 24th ECCMID / Barcelona Final Programme 12:30 – 13:30 Poster Area POSTER SESSION II: Molecular diagnostics of parasites P0704 Evaluation of a novel RIDA®GENE Entamoeba histolytica PCR for the detection of Entamoeba histolytica in stool specimen and liver abscess material L. Kastl* (Darmstadt, Germany), H. Von Thien, E. Tannich P0705 Detection and epidemiology of Dientamoeba fragilis – data from the Cologne metropolitan area 2012/2013 T. Hoppe, M. Steinmetz, U. Aurbach, C. Döffinger, U. Schallenberg, H. Wisplinghoff* (Cologne, Germany) P0706 Clinical performance of the BD MAX™ enteric parasite panel for detection of Cryptosporidium, Giardia lamblia, and Entamoeba histolytica DNA from unpreserved and fixed stool specimens* S.L. Knapp* (Durham, NC, United States), K.L. Lenz, M.D. Adams, R.J. Swan, J.J. Marley P0707 Contribution of multiplex real-time PCR for detection and differentiation of Enterocytozoon bieneusi and Encephalitozoon intestinalis in faecal samples of immunocompromised patients S.M. Alzagawy* (Ismailia, Egypt), E.E. El-Hamshary, H.Z. Rayan, G.H. Ibrahim Poster Sessions Sunday, 11 May 2014 P0710 Evaluation of the enteric parasite panel for the BD MAX™ system P. Mölling* (Växjö, Sweden), P. Nilsson, T. Ennefors, M. Neander, J. Ogren, S. Thulin Hedberg, M. Sundqvist P0711 Molecular characterisation of human isolates of Giardia lamblia from the south-west of the Islamic Republic of Iran using PCR – RFLP method K. Manouchehri Naeini* (Shahr-Ekord, Iran), M. Rezaeian, S.H. Hosseini P0712 Detection and genotypic characterisation of Giardia lamblia in a tertiary care centre in north India S. Malik* (Lucknow, India), U. Ghoshal, P. Pant, R. Shukla, U.C. Ghoshal P0713 Prospective cohort study to demonstrate rapid clearance of Giardia lamblia DNA from the gut after successful treatment W. Van den Bijllaardt* (Tilburg, The Netherlands), I.T. Overdevest, A.G. Buiting, J.J. Verweij P0714 P0715 P0716 Evaluation of rapid diagnostic tests for the detection of Cryptosporidium and Giardia T. Derks* (Hengelo, The Netherlands), K. Tasche-Borgreve, D. Vastert-Koop, M. Biezen v d-Brinkman, B. Mulder Contribution of Cryptosporidium real-time PCR to the diagnosis of intestinal cryptosporidiosis Y. Le Govic* (Lille, France), K. Guyot, G. Certad, C. Mary, B. Sendid, E. Viscogliosi, L. Favennec, E. Dei-Cas, E. Fréalle, E. Dutoit, ANOFEL Cryptosporidium National Network Advances in molecular detection of Toxoplasma gondii oocysts for application in environmental samples B. Prewein* (Vienna, Austria), R. Kunert, F. Allerberger, W. Ruppitsch P0718 18S PCR – detection of parasite DNA in otherwise sterile human clinical samples using a broadspecificity PCR-based approach H. Nielsen* (Copenhagen, Denmark), A. Al-Jubury, C. Stensvold, L. Andersen 13:30 – 14:30 Poster Area POSTER SESSION III: Diagnostic microbiology P0719 Do semi-automated methods improve EQA performance for identification of bacterial pathogens? E. Fagan* (London, United Kingdom), S. Seaton, C. Walton P0720 Forensic medicine: what is the contribution of microbiological laboratory to the establishment of cause of death? A retrospective study of 155 deaths M.e. Reverdy, A. Tristan, O. Dauwalder* (Bron, France), T. Guinet, G. Maujean, L. Fanton, D. Malicier, F. Vandenesch P0721 Proficiency of Romanian laboratories to perform microbial identification and susceptibility testing: results of participation in the external quality assessment schemes provided by CALILAB in 2013 M.C. Chifiriuc* (Bucharest, Romania), G. Sorescu, R. Popa, E. Borcan, L. Vasile, L. Marutescu, C. Popa P0722 The balanced scorecard as a management tool in a microbiology laboratory A. Anesi* (Lodi, Italy), D. Baroni, S. Asticcioli, S. Pittalis P0723 Exposure to hazard group 3 organisms in a district general hospital: pitfalls and lessons M. Strickland, F. Awad-El-Kariem* (Stevenage, United Kingdom) 24th ECCMID / Barcelona Final Programme Posters Evaluation of the automated real-time BD MAX™ enteric parasite panel assay M.D. Perry* (Cardiff, United Kingdom) A 4-year retrospective comparison of two target genes, REP 529 and B1, for Toxoplasma gondii detection by PCR, or why B1 should be abandoned S. Belaz* (Rennes, France), J.P. Gangneux, C. Guiguen, F. Robert-Gangneux Chairs, Speakers & Authors P0709 P0717 Exhibition Evaluation of a real-time PCR test for the diagnosis of intestinal infection caused by Giardia lamblia (duodenalis), Entamoeba histolytica, Dientamoeba fragilis and Cryptosporidium spp. A. Raglio* (Bergamo, Italy), M. Cosentino, M. Pegoraro, M.L. D’Annibale, A. Bruno, R. Maserati, R. Grande, G. Mazzei, V. Besutti, C. Farina 171 General Information P0708 Poster Sessions Sunday, 11 May 2014 P0724 European-wide external quality assurance exercises for the diagnoses of high threat bacteria – QUANDHIP R. Grunow* (Berlin, Germany), U. Sauer, A.M. Rohleder, D. Jacob P0732 Evaluation of two commercial GDH tests in a diagnostic algorithm for Clostridium difficile infection C. Verfaillie, W. Mistiaen, M. Herpol, I. Leroux-Roels, G. Claeys, J. Boelens* (Ghent, Belgium) P0725 Real-time PCR diagnosis of bacterial meningitis using the fast-track diagnostics’-bacterial meningitis kit M. Hofmann* (Junglinster, Luxembourg), U. Greffrath, M. Steimer, W. Carman, J. Sheikh, M. Antonio P0733 Colonisation of patients with non-toxigenic isolates of C. difficile: implications for infection control J. Smullen* (Harrogate, United Kingdom), L. Jenkinson, N. Weightman, K. Kerr P0734 C. diff Quik Chek Complete® for confirmation of toxin production by Clostridium difficile isolates M. Scholing* (Amsterdam, The Netherlands), L. Thiel, G.B. Linde P0735 Comparison of two matrix-assisted laser desorption ionization time-of-flight mass spectrometry systems, VITEK® MS and Bruker Biotyper for the identification of Clostridium difficile B. Shin* (Seoul, Korea), S. Hong, E.-C. Kim, E. Lee P0736 Comparison of two two-step algorithms for the diagnosis of Clostridium difficile infections: novel DiaSorin Liaison® algorithm compared to Meridian ImmunoCard® GDH and illumigene® assay J. Goret* (Bordeaux, France), J. Blanchi, S. Lacome, A. Petit, F. Barbut, C. Eckert, C. Bébéar, F. Mégraud P0737 Performance of VITEK®2 ANC system for Clostridium difficile identification compared with conventional methods (spore stain, odour) and multiplex PCR assay B. Shin* (Seoul, Korea), E. Lee P0738 Optimised diagnosis of Clostridium difficile infection; is there still room for improvement? Results of a European point prevalence study of C. difficile infection (EUCLID) H.M. Ashwin* (Leeds, United Kingdom), K.A. Davies, G.L. Davis, F. Lee, C.M. Longshaw, M.H. Wilcox P0739 Novel chemiluminescent immunoassays for the detection of Clostridium difficile infection A. Makristathis* (Vienna, Austria), S. Riss, A. Hirschl P0740 Clinical outcome and biological features of patients with Clostridium difficile infection according to testing methods L. Rame, N. Khanafer, C. Eckert, V. Lalande, F. Barbut* (Paris, France) 13:30 – 14:30 Poster Area POSTER SESSION III: Diagnosis of Clostridium difficile and other gastrointestinal infections P0726 Gastroenteritis and diarrhoea: a syndromic approach to laboratory diagnosis of disease A. Lual* (London, United Kingdom), J. UK Standards for Microbiology Investigations P0727 Antigen detection from faeces by separation-free fluorescence TPX assay technique J.M. Koskinen, J.M. Koskinen, H. Toivola* (Turku, Finland), M. Vesala, J. Soukka, J.O. Koskinen P0728 Evaluation of DiaSorin Liaison® test for diagnosis of C. difficile infection T. Lazzarotto* (Bologna, Italy), C. Vocale, F. Bellini, M.P. Landini P0729 Implementation of a nationally mandated microbiological testing protocol for C. difficile infection underestimates the true burden of disease L. Jenkinson* (Harrogate, United Kingdom), J. Smullen, N. Weightman, K. Kerr P0730 P0731 172 Evaluation of the impact of freezing on positive Clostridium difficile stools using VIDAS®GDH, VIDAS®CDA/B, Liaison® GDH, Liaison® A&B and C. dif Quik Chek Complete® J. Van Broeck* (Brussels, Belgium), E. Ngyuvula Mantu, K. Soumillion, M. Delmée Evaluation of a new 24-hour culture medium for the isolation of Clostridium difficile from stool samples J. Van Broeck* (Brussels, Belgium), E. Ngyuvula Mantu, K. Soumillion, M. Delmée 24th ECCMID / Barcelona Final Programme Poster Sessions Sunday, 11 May 2014 P0743 C. difficile diagnosis in a UK teaching hospital: a tale of two toxin tests N. Dawood, G.L. Vanstone, E. Yewnetu, D.J.F. Mack* (London, United Kingdom) P0744 Prevalence and pathogenicity of binary toxinpositive Clostridium difficile strains that do not produce toxins A and B C. Eckert* (Paris, France), L. Cathala, H. Marchandin, H. Jean Pierre, French network on C. difficile, F. Barbut P0745 Earlier detection of Salmonella strains using a selective chromogenic medium ChromID® ASAP J.M. Roche* (Craponne, France) P0746 Evaluation of the shiga toxin Quik Chek (TECHLAB®) test for the detection of shiga toxin-producing Escherichia coli (STEC) in human faecal samples K. De Rauw* (Brussels, Belgium), D. Piérard P0747 Rapid-test ImmunoCard STAT!® CGE for detection of intestinal parasites directly on faecal samples A.L. Engsbro* (Hvidovre, Denmark), H.B. Eriksen, A. Friis-Møller P0748 CASA chromogenic agar: an optimal medium for the isolation of clinically important Campylobacter spp. from stool samples L. Dalziel, M. Payne* (Newcastle-upon-Tyne, United Kingdom), J. Perry P0749 Comparison of the clinical and microbiological characteristics of Campylobacter and Helicobacter bacteraemia: the importance of time to blood culture positivity K. Yamamoto* (Tokyo, Japan), K. Hayakawa, S. Kutsuna, N. Takeshita, Y. Kato, S. Kanagawa, K. Yamada, K. Mezaki, T. Kirikae, N. Ohmagari 13:30 – 14:30 Poster Area POSTER SESSION III: Clostridium difficile: epidemiology and outcomes P0751 Alternative causes of diarrhoea and clinical manifestations of Clostridium difficile infection (CDI) among patients with a positive PCR and a negative toxin-detecting assay Y. Golan* (Boston, MA, United States), K. Johnson, P. Gjini, S. Husain, F. Magro, S. Doron, S. Bollinger, D. Snydman P0752 Population-based cohort study of Clostridium difficile infection (CDI) in the United States E. Dubberke* (St. Louis, MO, United States), D. Stwalley, C. Mahe, M. Olsen P0753 Second report from the European, multi-centre, prospective bi-annual point prevalence study of Clostridium difficile infection in hospitalised patients with diarrhoea (EUCLID) K.A. Davies* (Leeds, United Kingdom), G.L. Davis, H.M. Ashwin, F. Lee, C.M. Longshaw, M.H. Wilcox P0754 Towards a Europe-wide C. difficile infection surveillance S.M. Van Dorp* (Leiden, The Netherlands), A. Kola, M. Behnke, P. Gastmeier, D. Schmid, A. Hajdu, G.A. Kampinga, C. Suetens, E.J. Kuijper, European Clostridium difficile infection surveillance network P0755 C. difficile infections in acute care hospitals – results of the pilot study of a European surveillance initiative S.M. Van Dorp* (Leiden, The Netherlands), A. Kola, M. Behnke, P. Gastmeier, D. Schmid, A. Hajdu, G. Kampinga, C. Suetens, E.J. Kuijper, European Clostridium difficile infection surveillance network P0756 Cross-sectional study of community-acquired Clostridium difficile infection in north-east Scotland C. Smith, C. Sinclair, T. Lawes, I. Gould, D. O’Brien* (Aberdeen, United Kingdom) 24th ECCMID / Barcelona Final Programme Posters Can a human gut model of Clostridium difficile infection (CDI) be used to explain GDH-positive/ toxin-negative faecal samples seen in clinical practice? K. Davies* (Leeds, United Kingdom), C. Chilton, G. Crowther, S. Todhunter, J. Heritage, M. Wilcox BACTEC™ FX system as a tool for culturing gastric biopsies and Helicobacter pylori diagnosis (diagnosis of H. pylori by BACTEC™ FX) A. Peretz* (Tiberias, Israel), A. On, A. Koiefman, D. Brodsky, N. Isakovich, T. Glyatman, M. Paritsky Chairs, Speakers & Authors P0742 P0750 Exhibition Multicentre study of Clostridium difficile infection in Spain (studies II and III): updating the evolution of underdiagnosis of Clostridium difficile infection in a whole nation L. Alcala* (Madrid, Spain), E. Reigadas, M. Marín, A. Martín, P. Catalán, E. Bouza, Spanish Clostridium difficile Study Group 173 General Information P0741 Poster Sessions Sunday, 11 May 2014 P0757 Point-prevalence of Clostridium difficile infections (CDI) in Greek hospitals: a cross-sectional study A. Pefanis, E. Vogiatzakis, G. Petrikkos, L. Zerva, P. Gargalianos, M. Orfanidou, N. Sipsas, S. Smilakou, I. Spiliopoulou, C. Gogos* (Patras, Greece) P0758 Italian preliminary data obtained from the European, multi-centre, prospective bi-annual point prevalence study of Clostridium difficile infection in hospitalised patients with diarrhoea (EUCLID) P. Spigaglia, F. Barbanti, P. Mastrantonio* (Rome, Italy), K. Davies, C.M. Longshaw, M. Wilcox P0759 Polish surveillance programme of Clostridium difficile infections reveals persistently high prevalence of Clostridium difficile type 027 H. Pituch* (Warsaw, Poland), D. Lachowicz, P. Obuch-Woszczatynski, G. Mlynarczyk, C. Harmanus, E. Kuijper P0760 Clostridium difficile infection in a French university hospital: molecular characteristics of isolates and factors associated with severity N. Khanafer* (Lyon, France), F. Barbut, C. Eckert, M. Perraud, F. Vandenesh, C. El Guerche Seblain, P. Vanhems P0761 P0762 P0763 P0764 174 Assessment of severity of Clostridium difficile infection using ATLAS score by the National Institute for Infectious Diseases Prof Dr Matei Bals, Bucharest S. Benea* (Bucharest, Romania), G.A. Popescu, D. Florea, I.R. Crismaru Outbreak of Clostridium difficile PCR ribotype 027 – the recent experience of a regional hospital M. Oleastro* (Lisbon, Portugal), M. Coelho, M. Gião, S. Coutinho, S. Mota, A. Santos, J. Rodrigues, D. Faria Surveillance of Clostridium difficile binary toxin and ribotype 027 using laboratory data in Germany J. Becker* (Frankfurt, Germany), T. Braeu, M. Schellberger The clinical utility of diagnostic tests for Clostridium difficile infection: the prediction of recurrence of infection T. Planche* (London, United Kingdom), K.A. Davies, D. Crook, N. Shetty, M. Wren, P.G. Coen, I. Monahan, M.H. Wilcox 24th ECCMID / Barcelona Final Programme P0765 Recurrence and/or death after a first Clostridium difficile symptomatic infection: influence of prior therapy by proton pump inhibitor O. Dos Santos, S. Boisset, O. Epaulard* (Grenoble, France) P0766 Recurrent Clostridium difficile infection: clinical relevance, risk factors and prognosis T. L.-Larrainzar Coghen, D. Rodriguez-Pardo* (Barcelona, Spain), B. Almirante, V. Rodríguez, C. Ferrer, C. Pigrau, N. Fernández-Hidalgo, M. Puig-Asensio, T. Pumarola, A. Pahissa P0767 Outcomes related to recurrent Clostridium difficile infections – inpatient and outpatient comparison from a large secondary database analysis G.J. Escobar, J.M. Baker, S.X. Li, Y. Xie* (Whitehouse Station, NJ, United States), S.W. Marcella, R.N. Kumar, P. Kipnis P0768 Attributed costs of hospital-acquired Clostridium difficile associated diarrhoea in Germany C. Huebner* (Greifswald, Germany) P0769 Advances in diagnostic technology suggest limitations in the current case definition and understanding of healthcare-associated Clostridium difficile E. Herding, D. Williams, G. Hansen* (Minneapolis, United States) P0770 Clinical implications of Clostridium difficile infection (CDI) in kidney transplant recipients (KTR): a retrospective case-control study J. Origuen, C. Lumbreras, M.A. Orellana, M.A. Pérez-Jacoiste, A. García-Reyne, T. Ruiz-Merlo, N. Carrasco, R. San Juan, M. Fernández-Ruiz, J.M. Aguado* (Madrid, Spain) P0771 Detecting Clostridium difficile spores from hospital surfaces. Which method is best? T. Claro* (Dublin, Ireland), S. Daniels, H. Humphreys P0772 C. difficile reservoirs and potential risk of transmission in three patient groups: asymptomatically colonised, C. difficile excretors and infected patients K. Bisnauthsing, A. Patel, C. Ward, J. Biswas* (London, United Kingdom), D. Wyncoll, E. Van Kleef, S. Goldenberg Poster Sessions Sunday, 11 May 2014 Low colonisation rate of Clostridium difficile among patients and healthcare workers in Sweden O. Säll* (Örebro, Sweden), T. Norén Immediate automated detection of nosocomial transmission clusters (hotspots) D. Flury* (St. Gallen, Switzerland), M. Hoffmann, T. Meier, P. Kohler, M. Schreiner, M. Schlegel P0782 Prevalence, molecular epidemiology and risk factors for carriage of Clostridium difficile amongst children <2 years of age in Oxfordshire, UK N. Stoesser* (Oxford, United Kingdom), D.W. Eyre, A. Vaughan, G. Pill, D.W. Crook, T.E. Peto, A.S. Walker P0783 A longitudinal study of Clostridium difficile carriage at a Western Australian tertiary hospital N.F. Foster* (Nedlands, Australia), S.L. Ditchburn, C.N. Duncan, T.L. Scheller, H.E. Hong, D.L. Patterson, T.V. Riley, A.C. Clements P0784 Clostridium difficile infection in patients with acute myelogenous leukemia and patients undergoing allogeneic stem cell transplantation – epidemiology and risk factor analysis M.J.G.T. Vehreschild* (Cologne, Germany), D. Weitershagen, L. Biehl, D. Tacke, D. Waldschmidt, U. Töx, M.V. Bergwelt-Bailldon, O.A. Cornely, J.J. Vehreschild P0785 Storage duration of red blood cell transfusion and Clostridium difficile infection: a within-person comparison M.A.M. Rogers* (Ann Arbor, United States), D. Micic, N. Blumberg, V.B. Young, D.M. Aronoff Implementation of contemporary molecular methods for improving the diagnosis and surveillance of Clostridium difficile infections in Bulgaria E. Dobreva* (Sofia, Bulgaria), I.N. Ivanov, K. Ivanova, G. Asseva, P. Petrov, T. Velinov, T. Kantardjiev P0777 Evaluation of a rapid molecular test to genotype C. difficile strains C. Eckert* (Paris, France), N. Poccardi, G. Sika, A. Petit, F. Barbut P0778 The use of MVLA and whole genome sequencing to study the relatedness of Clostridium difficile isolates of ribotypes 106 and 174 within the Midlands S. Manzoor, C.B. Thomson, G. Kapatai, N. Loman, K. Hardy, P.M. Hawkey* (Birmingham, United Kingdom) P0786 Comparative efficacy of peracetic acid and hypochlorite on Clostridium difficile spores L. Suzon, F. Barbut* (Paris, France) P0787 Is our current cleaning method effective at eradicating C. difficile? L. Steriopoulos* (Kilmarnock, United Kingdom) P0779 Emergence of Clostridium difficile type 176 in Czech Republic V. Beran* (Ostrava, Czech Republic), E. Kuijper, C. Harmanus, I. Sanders, S. Van Dorp, J. Janeckova, O. Kopecky, L. Barekova, D. Chmelar, I. Ciznar P0788 Improved documentation of inpatient Clostridium difficile infection (CDI) in electronic discharge summaries following an intervention R. Connolly, K. Burns* (Dublin, Ireland) P0789 P0780 Polymerase chain reaction ribotyping revealed outbreak caused by Clostridium difficile PCRribotype 027 in dialysis patients in Poland D. Lachowicz, G. Szulencka, P. Obuch-Woszczatynski, H. Pituch* (Warsaw, Poland) Clostridium difficile associated diarrhoea: a comprehensive cost-of-illness analysis of inpatient cases S.M. Heimann* (Cologne, Germany), O.A. Cornely, H. Wisplinghoff, M.J.G.T. Vehreschild, B. Franke, I. Dohle, F. Müller, J.J. Vehreschild 24th ECCMID / Barcelona Final Programme Posters P0776 175 Chairs, Speakers & Authors P0775 Non-toxigenic Clostridium difficile colonisation and risk of subsequent C. difficile infection M. Natarajan, M.A.M. Rogers* (Ann Arbor, United States), J. Bundy, D. Micic, K. Rao, S.T. Walk, K. Santhosh, V.B. Young, D.M. Aronoff P0781 Exhibition P0774 Clostridium difficile: impact of colonisation versus transmission on the development of infection – results from a prospective observational study S. Tschudin Sutter* (Baltimore, MD, United States), K.C. Carroll, P.D. Tamma, M.L. Sudekum, B.C. Ellis, J. Bartlett, T.M. Perl General Information P0773 Poster Sessions Sunday, 11 May 2014 P0798 Antimicrobial susceptibility and molecular characterisation of moxifloxacin resistance from Korean Clostridium difficile PCR ribotype 078 H.Y. Kim* (An-Yang, Korea), J.W. Byun, A. Cho, M.H. Lee, B. Kim SMT 19969 for Clostridium difficile infection (CDI): comparative efficacy compared to fidaxomicin and vancomycin in the hamster model of CDI R. Vickers* (Abingdon, United Kingdom), J. Teague, P. Thomas, P.A. Warn P0799 Antimicrobial susceptibilities of Clostridium difficile isolated in London, UK K. Williams, D. Ready, N. HarrisBrown, N. Murphy, C. Ryan, M. Cairns, R. Manuel* (London, United Kingdom) Persistence and removal of fidaxomicin from C. difficile spores, and impact on spore recovery C.H. Chilton* (Leeds, United Kingdom), H.M. Ashwin, G.S. Crowther, C.M. Longshaw, M.H. Wilcox P0800 Low propensity of Clostridium difficile strains from humans to develop resistance against the novel combination nisin-miconazole J. Dallow, E. Siegwart* (Fordham, United Kingdom), S. Self, K. Knights P0801 SMT 19969: a novel agent for Clostridium difficile infection – summary results from in vitro microbiology and a randomised double blind phase 1 clinical trial R.J. Vickers* (Abingdon, United Kingdom), D.M. Citron, E.J.C. Goldstein, E.L. Best, M.H. Wilcox P0802 In vitro activity of MCB3681 against Clostridium difficile strains M.U. Rashid, A. Dalhoff, A. Weintraub, C.E. Nord* (Stockholm, Sweden) P0803 Snare™ antibacterials: novel nanoparticulate nucleic-acid based therapeutics for the treatment of Clostridium difficile infections and prevention of recurrence T. Diaz Calvo* (Norwich, United Kingdom), K. Hatzixanthis, P. Warn, A. Narbad, M. McArthur P0804 DAV131, an oral adsorbent-based product, exerts a dose-dependent protection of hamsters against moxifloxacin-induced Clostridium difficile lethal infection C. Miossec, S. Sayah-Jeanne, V. Augustin, E. Chachaty, W. Weiss, T. Murphy, M. Pulse, A. Andremont, J. De Gunzburg* (Paris, France) P0805 In vitro activity of surotomycin (formerly CB-183,315) against 126 clinical isolates of Clostridium difficile O. Valentin, C. Eckert, L. Chesnel, F. Barbut* (Paris, France) P0806 In vitro demonstration of inhibition of Clostridium difficile by commercial probiotics: a real time study M. Fredua-Agyeman* (London, United Kingdom), A. Basit, P. Stapleton, A. Beezer, S. Gaisford 13:30 – 14:30 Poster Area POSTER SESSION III: C. difficile: antimicrobial susceptibility and treatment P0790 P0791 P0792 P0793 Antibiotic susceptibility of surotomycin and five other antibiotics against Clostridium difficile isolates, collected at a pan-European survey in 2008 (n=119) I.M. Sanders, C. Harmanus, S. Debast* (Leiden, The Netherlands), E.J. Kuijper Characterisation and antimicrobial susceptibility of Clostridium difficile isolates from humans, food producing and companion animals, 2007-2013, Italy F. Agnoletti* (Treviso, Italy), E. Mazzolini, R. Rigoli, G. Muffato, G. Merialdi, C. Magistrali, L. Bano, C. Bacchin, E. Tonon, I. Drigo P0794 Evaluation of antimicrobial susceptibility of Clostridium difficile isolates from Bulgaria K. Ivanova* (Sofia, Bulgaria), E. Dobreva, I. Ivanov, G. Asseva, P. Petrov, T.Z. Velinov, T. Kantardjiev P0795 In vitro susceptibility of Clostridium difficile isolates to fidaxomicin, Austria 2012 V. Zeinzinger* (Vienna, Austria), S. Huhulescu, A. Fiedler, F. Allerberger, A. Indra P0796 P0797 176 Experience of using fidaxomicin for selected C. difficile cases at County Durham and Darlington Foundation Trust in the north east of England: early findings! D. Nayar* (Durham, United Kingdom), S. Brown, D. Allison, C. Aldridge, L. Lim, J. Sloss, D. Kejariwal, A. Dhar Efficacy of tapered fidaxomicin dosing regimens to treat simulated Clostridium difficile infection (CDI) in an in vitro gut model C.H. Chilton* (Leeds, United Kingdom), G.S. Crowther, S.L. Todhunter, H.M. Ashwin, F. Lee, C.M. Longshaw, M.H. Wilcox 24th ECCMID / Barcelona Final Programme Poster Sessions Comparison of practical issues associated with introduction of different molecular assays as a first-line test for Clostridium difficile screening B.J. Parcell, J. Shone, G.V. Orange, J.E. Coia* (Glasgow, United Kingdom), A. Whyte, D.L. Yirrell P0808 Use of allelic exchange to characterise the impact of three separate mutations in rpoB on the fitness of Clostridium difficile and sensitivity to fidaxomicin A.W. Dempster* (Nottingham, United Kingdom), M.M. Collery, S.A. Kuehne, C.M. Longshaw, N.P. Minton P0816 An evaluation of three different molecular assays for detecting toxigenic Clostridium difficile in human faecal samples A. Ingebretsen* (Oslo, Norway), M.D. Borras, F. Müller, E. Lingaas P0817 Three years of loop-mediated isothermal amplification (LAMP) and toxigenic culture (TC) for Clostridium difficile diagnosis T. Noren* (Örebro, Sweden), K. Johansson, M. Unemo P0818 Diagnosis of Clostridium difficile infections (CDI): prospective clinical evaluation comparing two molecular tests D. Ali, B. Sémin, A. Guillouzouic, C. Bourigault, D. Boutoille, J. Caillon, D. Lepelletier, P. Bémer* (Nantes, France) P0819 Performance characteristics the cobas® Cdiff Test, a fully-automated assay on the cobas® 4800 system to detect Clostridium difficile in clinical stool specimens D. Fairley* (Belfast, Ireland), J. McKenna, J. Weaver, P. Coyle P0820 Toxigenic Clostridium difficile detection with the cobas® Cdiff Test on the cobas® 4800 system from stool specimens of patients from Hvidovre, Denmark and Regensburg, Germany A. Hiergeist* (Regensburg, Germany), S. Foerester, S. Lowe, Y. Ohhashi, D. Kosarikov, J. Osiecki, A. Line, O. Engsbro, H. Westh, U. Resichl P0821 Evaluation of the EasyScreen™ C. difficile detection kit for tcdA and tcdB K. Carson* (Nedlands, WA, Australia), S. Siah, D. Millar, B. MacKenzie, J. Melki, T. Riley P0822 Evaluation of a molecular test based on isothermal helicase-dependent amplification to detect Clostridium difficile toxin A gene C. Eckert* (Paris, France), A. Petit, E. Holscher, V. Lalande, F. Barbut P0823 Impact of Clostridium difficile associated disease (CDAD) due to isolates carrying binary toxin genes on recurrence of C. difficile associated colitis and patient clinical outcome M. Deffontaine, F. Hamdad, M. Belmekki, M. Biendo* (Maurens Scopont, France), C. Casado 13:30 – 14:30 Poster Area POSTER SESSION III: New developments in molecular diagnosis of C. difficile P0809 A three-stage algorithm for C. difficile testing E. Trautt* (Oldham, United Kingdom), C. Chadwick, D. Dean, S. Norris, J. Fielding, P. Taafe P0810 3-step algorithm to improve CDI diagnosis and ensure optimal patient management and infection control P. Marone* (Pavia, Italy), E. Travaglino, M. Brandolini, M. Corbella, E. Giacobone, A. Piralla, P. Cambieri P0811 Diagnosis of Clostridium difficile infection: comparison of different methods on specimens collected for a cohort study in a large tertiarycare Italian hospital N. Della Malva, R. Dei, E. Mantengoli, P. Pecile, A. Bartoloni* (Florence, Italy), G.M. Rossolini P0812 Comparison between different diagnostic laboratory assays in the diagnosis of C. difficile infection D. Mileto* (Milan, Italy), S.G. Rimoldi, C. Pagani, A. Mancon, M.R. Gismondo P0813 Comparison of commercially available real-time PCR test systems for the diagnosis of Clostridium difficile infections A. Boesl* (Feldkirch, Austria), K. Baruschke, R. Stockinger, G. Hartmann, H. Dirschmid, U. Gruber-Mösenbacher, F. Offner P0814 Diagnosis of Clostridium difficile in a routine laboratory: comparison between two isothermal amplification methods, real-time PCR, cell cytotoxicity test and culture M. Becker* (Düsseldorf, Germany), R. Guadarrama-Gonzalez, C. MacKenzie 24th ECCMID / Barcelona Final Programme 177 Chairs, Speakers & Authors P0815 Exhibition Starving the superbug: novel antimicrobial therapies that target selenium metabolism to treat C. difficile infection C. Roder* (Geelong, Australia), E. Athan, M.J. Thomson General Information P0807 Posters Sunday, 11 May 2014 Poster Sessions Sunday, 11 May 2014 P0824 Inclusive and specific detection of toxinogenic Clostridium difficile by the novel isothermal amplification technology, SIBA® P. Matero* (Espoo, Finland), R. Kärkkäinen, J. Flinck, T. Siljander, T. Tomperi, S. Kukkamaa, P. Rikkinen-Holm, K. Pousi, S. Filén, M. Mäki P0825 Rapid random access diagnosis of Clostridium difficile in the laboratory using DiaSorin® LIAISON® antigen and toxin testing and isothermal amplification methods in a two-step algorithm M. Becker, I. Widera, D. Kara, R. GuadarramaGonzalez, C. MacKenzie* (Düsseldorf, Germany) P0826 P0827 Development and performance of the QIAGEN artus C. difficile QS-RGQ kit for detection of toxigenic C. difficile using the QIAsymphony RGQ MDx system R. Hawwa* (Cambridge, United States), A. Zuniga, H. Reiske, T. Glavan, K. Cerow, T. Pelletier, W. O’Brien, M. Exner, A. Nesselrodt Evaluation of the presence of binary toxin in hospitalised patient with suspected Clostridium difficile infection P. Pedroni* (Pero, Italy), A. Bonamini, A. Indelicato, P. Spigaglia, F. Barbanti, P. Mastrantonio 13:30 – 14:30 P0829 P0830 178 Food-poisoning aetiology in Catalonia: 2003-2013 T. Cornejo Sánchez* (Barcelona, Spain), N. Piedra-Carrasco, J.J. González-López, S. Guix, A. Martínez, N. Torner, Working group for the study of outbreaks of acute gastroenteritis in Catalonia, T. Pumarola, A. Domínguez, R. Bartolomé P0832 Epidemiology of Campylobacter gastrointestinal tract infections in humans in the Czech Republic J. Bardon, V. Husickova* (Olomouc, Czech Republic), M. Roderova, I. Kolackova, R. Karpiskova, T. Stosova, M. Kolar P0833 Campylobacter jejuni infection in Portugal: high rates in hospital settings M. Oleastro* (Lisbon, Portugal), A. Santos, S. Ferreira, A. Rodrigues, C. Júlio P0834 Combined ciprofloxacine and tetracycline resistance among C. jejuni human faecal isolates in the largest Croatian county: a cross-sectional study M. Carev* (Split, Croatia), A. Novak, A. Jeroncic, M. Tonkic P0835 Detection of Campylobacter in stool specimens within the African setting: molecular methodologies are essential and indispensable tools A.M. Smith* (Sandringham, South Africa), H. Ismail, N.A. Page, S.A. Madhi, K.H. Keddy Poster Area POSTER SESSION III: Gastrointestinal infections and pathogens P0828 P0831 P0836 Disease burden of selected gastrointestinal pathogens in Australia, 2010: comparing number of gastroenteritis cases and deaths, disability adjusted life years (DALYS) and DALYS/case K. Gibney* (Melbourne, Australia), J. O’Toole, M. Sinclair, K. Leder Investigation of non-travel associated Shigella flexneri serotype 3a infections in adult males in England S. Horridge* (London, United Kingdom), M. Day, T. Peters, C.R. Lane, C. Jenkins P0837 Viral and bacterial enteropathogens in a local hospital in Spain for 8 years: prevalence and sensitivity (2004-2011) A. Sánchez-Maroto* (Madrid, Spain), J.A. Pérez García, S. Illescas Fernández-Bermejo Application of a novel method for demonstrating frequent contamination of groundwater with verotoxigenic E. coli (VTEC) S. Kavanagh, M. Cormican, K. Carney, B. MacDomhnaill, D. Morris* (Galway, Ireland) P0838 Comparison of two methods for the detection of verotoxins in human faecal samples during an outbreak of HUS in Apulia, southern Italy R. Monno, A. Parisi, E. Baglivo, C. Capolongo, C. Calia, V. Cinquepalmi, G. Miragliotta* (Bari, Italy) Food safety in school canteens: food handlers, utensils and food as a potential source of pathogenic microorganisms S. Quinteira* (Vila Nova Famalicao, Portugal), A. Gomes, S. Alves, C. Diniz, N. Ferreiro, J. Proença, M.J. Neuparth 24th ECCMID / Barcelona Final Programme Poster Sessions Sunday, 11 May 2014 P0839 Gnd-typing as a tool for rapid epidemiology of enteroaggregative Escherichia coli S.I. Hauswaldt, C. Dracoloulos, E. Adomakoh, M. Kalitzky, W. Solbach, J.K. Knobloch* (Lübeck, Germany) P0849 Outbreak of astrovirus type 5 gastroenteritis in a residential care home for older people A. Jarchow-MacDonald* (Dundee, United Kingdom), S. Halley, D. Chandler, R. Gunson, S. Shepherd, B. Parcell P0840 Epidemiology and pathological significance of enteroaggregative Escherichia coli in Danish patients B. Jensen* (Copenhagen, Denmark), A. Friis-Møller, K.E.P. Olsen, A.M. Petersen, J. Engberg, K.A. Krogfelt P0850 P0841 Results from a ten-year PCR screening for enterohaemorrhagic Escherichia coli in children in a Swedish county A. Matussek* (Jönköping, Sweden), I.M. Einemo, S. Löfdahl, S. Löfgren Emerging trend of Vibrio in urban Bangladesh, a retrospective study of serotype distribution and antibiotic resistance A.I.M.S. Ud-Din, S.U.H. Wahid, N. Akter, H.A. Latif, K. Nahar, M.A. Hossain, D. Ahmed* (Dhaka, Bangladesh) Evaluation of luminex xTAG®-GPP (gastrointestinal pathogen panel) in the diagnostic of acute diarrhoeal diseases C. Casañ* (Paterna, Spain), F. Grosson, M.D. Ocete, J.L. Ramos, N. Tormo, R. Guna, R. Medina, C. Gimeno P0852 A comparison of masscode vs luminex xTAG® gastrointestinal panel for the simultaneous diagnosis of multiple gastrointestinal pathogens L.J. Pankhurst* (Oxford, United Kingdom), L. Macfarlane-Smith, L.W. Anson, K. Davies, H. Ashwin, T.E.A. Peto, A.S. Walker, M.H. Wilcox, D.W. Crook P0853 Evaluation of a commercial system (R-Biopharm RIDA®GENE) for molecular detection of gastrointestinal infections T.M. Leegaard* (Lørenskog, Norway), B. Follin-Arbelet, T.H. Nguyen, H. Esnaashari, T.E. Ranheim, H.S. Tunsjø, A.K. Kvissel P0844 Detection of Salmonella arizonae in an enteric fever outbreak by the ID 32 GN automated system E. Gunal* (Diyarbakir, Turkey), H. Erdem P0845 Extended-spectrum-beta-lactamase-producing Salmonella enterica serovar Typhi of Central American origin isolated in Spain N. Piedra Carrasco* (Barcelona, Spain), T. Cornejo-Sánchez, M.N. Larrosa, R.M. Bartolomé, C. Gulin, A. Sánchez-Montalva, F. Salvador, A.M. Planes, J.J. González-López P0846 Unusual non-typhoidal Salmonella serotypes dispersed in animals and environmental sources in Angola P. Antunes, J. Campos* (Porto, Portugal), J. Mourão, L. Margalho, T. Ribeiro G, C. Novais, L. Peixe P0854 Validation of a diagnostic tool for multiplex screening of gastrointestinal pathogens on multiplex QCMD panels: GastroFinder™ SMART 17 J. Van der Velden* (Maastricht, The Netherlands), Y. Ozog, G. Simons P0847 Salmonella Mbandaka – 15 years of successful spread of ST413 clone in Poland D. Wasyl* (Pulawy, Poland), A. Hoszowski, M. Zajac P0855 P0848 Changes in genotypic distributions of human group A rotavirus after vaccine introduction in Korea H.S. Kim* (Hwaseong, Korea), D.H. Whang, S.H. Lee, H.S. Kim, J.S. Kim, W. Song Increased recovery using the BD MAX™ enteric bacterial panel* for rapid detection of DNA from Salmonella spp., Shigella spp., Campylobacter, and shiga-toxin producing E. coli M. Porter* (Sparks, MD, United States), A. Lainesse, C. Whiteford 24th ECCMID / Barcelona Final Programme 179 Posters P0851 Chairs, Speakers & Authors Ciprofloxacin and azithromycin resistant S. paratyphi A presenting as relapse R.A. Corrigan* (Buckinghamshire, United Kingdom), M.M. Raza POSTER SESSION III: Molecular diagnosis of gastrointestinal bacterial infections Exhibition P0843 A rapid method for monitoring large water volumes for verotoxigenic Escherichia coli (VTEC) S. Kavanagh, M. Cormican, K. Carney, B. Macdomhnaill, D. Morris* (Galway, Ireland) Poster Area General Information P0842 13:30 – 14:30 Poster Sessions Sunday, 11 May 2014 P0856 Time motion analysis of the BD MAX™ enteric bacterial panel (EBP) compared to conventional methodologies for the detection of stool pathogens J. Mortensen* (Cincinnati, United States), S. Hanna, C. Ventrola P0865 Distribution of six virulence factors in Aeromonas species isolated from patients suffering from diarrhorea in Spain F. Galan-Sanchez, I. Guerrero-Lozano, P. Marin-Casanova, A. Garcia-Tapia, M.A. Rodriguez-Iglesias* (Cadiz, Spain) P0857 Evaluation of the BD MAX™ enteric bacterial panel assay for the detection of bacterial pathogens in diarrhoeal stool specimens K. McAulay* (Reading, United Kingdom), V. Lock, A. Stacey, N. Virgincar, S. Iyer P0866 P0858 A multicentre evaluation of the BD MAX™ enteric bacterial panel for the detection of Salmonella spp., Shigella spp., Campylobacter spp., and shiga-toxin-producing Escherichia coli J. Mortensen* (Cincinnati, United States), S. Harrington, B. Buchan, C. Doern, R. Fader, M. Ferraro, D. Pillai, J. Rychert Comparison of the performance of several one step rt-qPCR enzymes with fast-track diagnostics FTD mix M. Heckmann* (Junglinster, Luxembourg), S. Balbier, C. Gruhn, H. Nummer, M. Hofmann, M. Steimer, W. Carman P0867 Comparison of two multiplex PCR for diarrhoeagenic Escherichia coli diagnosis N. Iglesias Nunez* (Madrid, Spain), A. Arroyo Fajardo, P. Trevisi, A. Sarría Visa, B. López Quintana, C. Ladrón de Guevara, C. Toro Rueda P0868 Evaluation of a new PCR-based platform for the detection and identification of viruses or bacteria from swab transport devices K. Khan* (Slough, United Kingdom) P0869 Evaluation of MSwab direct nucleic acid extraction for detection of viruses, bacteria and parasites in faecal samples using fast-track diagnostics real-time multiplex kits M. Hofmann* (Junglinster, Luxembourg), A. Hagen, S. Castriciano, M. Heckmann, M. Steimer, W. Carman P0859 Evaluation of the first microarray-based molecular screening test for eight gastrointestinal pathogens using the automated NanoChip® platform M.D. Perry* (Cardiff, United Kingdom) P0860 Evaluation of the Verigene® EP IUO test for the rapid detection of bacterial and toxin causes of gastrointestinal infection S. Novak-Weekley* (North Hollywood, United States), E.M. Marlowe P0861 A novel, fast and specific isothermal nucleic acid amplification test for Salmonella enterica subsp. enterica J. Flinck, A. Wester, M. Mäki, J. Saharinen* (Espoo, Finland) P0862 Detection of bacterial pathogens associated with acute diarrhoea using multiplex-PCR system E. Raukas* (Pärnu, Estonia), A. Looväli, R. Pulk P0863 Differentiation of epidemic and endemic strains of Salmonella enterica serovar Newport by PCR detection of a truncated bapA chromosomal gene R.A. Horton* (Addlestone, United Kingdom), R. Card, L.P. Randall, C. Teale P0864 Screening with vanA/B PCR to detect vancomycinresistant enterococci using the Siemens VERSANT® KPCR system M. Bongaerts* (Sittard-Geleen, The Netherlands), E.J. Van Hannen, K.C.J. Frijns, M.E.L.M. Manders, E.R. Heddema 180 24th ECCMID / Barcelona Final Programme 13:30 – 14:30 Poster Area POSTER SESSION III: Helicobacter pylori P0870 Polymorphisms in interleukin-1beta gene associated with peptic ulcer and gastric cancer risk in Helicobacter pylori-positive patients I.B. Ramis* (Rio Grande, Brazil), J.S. Vianna, P.C.B. Halicki, T.B. Gautério, A. Von Groll, P.E.A. Silva P0871 Prevalence of Helicobacter pylori gene alleles among patients with different gastric lesions Z. Said* (Cairo, Egypt), S. El-Shazly, S. Mustafa, N. Abd El Rahman, K. El bassel, N. Abd El Haliem, M. Metawea P0872 Detection of prophage and CRISPR loci in Helicobacter pylori E. Aznar, T. Alarcón* (Madrid, Spain), M. López-Brea Poster Sessions P0876 Sensitivity evolution of Helicobacter pylori during the years 2006 to 2013 in the south of Spain. Treatment alternatives F. Franco Álvarez de Luna* (Minas de Riotinto, Spain), C. Santos Rosa, R. Sáenz Solís, J.H. García Vela, A. Duque Calero P0877 Evaluation of Helicobacter pylori vacA, cagA genotypes and correlation with clinical outcome in Iranian patients with dyspepsia M. Alikhani* (Hamadan, Iran), A. Majlesi, M. Jaefari, M. Arebestani 13:30 – 14:30 Poster Area Identification of M. tuberculosis using MALDI-TOF MS A. Mazzarelli, C. Venditti, S. D’Arezzo, E. Bordi, A. Piscini, G. Delogu, C. Nisii, A. Di Caro* (Rome, Italy) P0883 Outbreak of tuberculosis in a Norwegian dance academy delineated by mass spectrometry I. Szpinda* (Oslo, Norway), A. Ingebretsen, W. Egge-Jacobsen, P. Gaustad, T. Tonjum P0884 A 3-year experience with a multiplex highthroughput molecular assay for characterisation of genetic markers in the Mycobacterium tuberculosis genome S. Sengstake* (Amsterdam, The Netherlands), I. Bergval, A. Schuitema, J. De Beer, E. Abadia, P. Klatser, C. Sola, D. Van Soolingen, R. Anthony P0885 Whole genome sequencing and epidemiological analysis does not provide evidence for crosstransmission of M. abscessus in a cohort of paediatric cystic fibrosis patients in a tertiary referral centre K.A. Harris* (London, United Kingdom), A. Underwood, D.T.D. Kenna, P. Aurora, G.L.J. Dixon P0886 Evaluation of Copan Myco-TB system for a rapid and efficient decontamination of mycobacterial specimens L. Mancinelli* (Rome, Italy), L. Coltella, G. Pizzichemi, E. Galeno, S. Gobbi, S. Landi, D. Menichella, C. Russo P0887 Application of an interferon-gamma release assay in healthcare workers M. De Paschale, C. Morazzoni, R.A. Bonazzina, L. Gorla, C. Agrappi, P. Mirri, M.T. Manco, L. Belvisi, A. Gatti, P. Clerici* (Legnano, Italy) P0888 Demonstration of diagnostic utility of a new TB serology rapid test in case-control studies of clinically proven tuberculosis cases A. Tam* (San Mateo, United States), I. Kwok, V. Chan, G. Wang, V. Choi, J. Wong-Lee P0889 The microbiological diagnosis of tuberculosis meningitis: results of Haydarpasa-1 study H. Erdem, D. Ozturk-Engin, N. Elaldi, S. Gulsun, G. Sengoz, A. Crisan, I. Somuncu Johansen, A. Inan* (Istanbul, Turkey), M. Nechifor, T. Tuberculosis Meningitis Study Group POSTER SESSION III: Diagnosis of mycobacterial infections: from genetics to MALDI-TOF P0878 Comparison of two interferon-gamma release assays for the screening of healthcare workers in a Swiss university hospital P. Bittel* (Berne, Switzerland), D. Mayor, P. Iseli, S. Pfister, F. Suter-Riniker P0879 A false-positive immunochromatographic assay associated with Elizabethkingia meningoseptica for rapid identification of Mycobacterium tuberculosis complex in liquid culture media J. Lin* (Changhua City, Taiwan), L. Shih, C. Lin P0880 Evaluation of the newly developed Mycobacterium library of Bruker MALDI Bbiotyper® for mycobacteria MALDI-TOF MS identification in practical routine P. Nguyen, S. Lali, B. Marchetti* (Montigny le Tilleul, Belgium), D. Fameree, D. Govaerts P0881 MALDI-TOF MS for direct identification of nontuberculous mycobacteria (NTM) from positive MGIT™ cultures of patient specimens A.B. Pranada* (Dortmund, Germany), M. Timke, E. Witt, M. Kostrzewa 24th ECCMID / Barcelona Final Programme Chairs, Speakers & Authors Helicobacter pylori antibodies in patients with idiopathic thrombocytopenic purpura N. Hanafi* (Alexandria, Egypt), I. Mikhael, D. Younan P0882 Exhibition P0874 Distribution of vacAi alleles in characterised vacAs/m Helicobacter pylori isolated in Moroccan population M. El Khadir* (Fès, Morocco), S.A. Boukhris, D.A. Benajah, K. El Rhazi, S.A. Ibrahimi, C. Nejjari, A. Amarti, B. Bennani 181 General Information P0873 Posters Sunday, 11 May 2014 Poster Sessions Sunday, 11 May 2014 13:30 – 14:30 Poster Area P0898 POSTER SESSION III: Epidemiological and clinical studies on non-tuberculous mycobacteria P0890 P0891 No impact of respiratory colonisation with Mycobacterium avium-intracellulare in patients with cystic fibrosis on the long-term course of the forced expiratory volume in one second C. Albrecht* (Hanover, Germany), F. Ringshausen, S. Ott, D. Wagner, J. Rademacher, T. Welte, M. Schneider, M.W. Pletz Prevalence of non-tuberculous mycobacteria (NTM) in a cystic fibrosis (CF) unit of Madrid L. Llorca* (Madrid, Spain), D. Domingo, J. Martiáñez, M.D. Guerrero, R. Girón, L. Cardeñoso P0892 Nontuberculous mycobacteria colonisation and disease in cystic fibrosis patients R. Gilarranz* (Las Palmas de Gran Canaria, Spain), F.J. Chamizo, M.I. Campos-Herrero, M.A. García, G. Cabrera, J. Cuyas, J.A. Caminero P0893 A follow up on two outbreaks of nontuberculous mycobacterial skin and soft tissue infection in Venezuela; identifying the infection source J. Torres-Coy* (Caracas, Venezuela), B.A. Rodriguez-Castillo, J.H. De Waard P0894 Rapidly growing mycobacteria in Singapore: infections and treatment outcome D. Lye, S. Tang* (Singapore, Singapore), L. Sng, R. Jureen, L. Hsu P0895 Epidemiology of nontuberculous mycobacteria at a medical centre in Taiwan, 2000-2012 P. Hsueh* (Taipei, Taiwan), J. Chien, C. Lai, W. Sheng P0896 Outcome and prognostic factors of nontuberculous mycobacteriosis in France: a cohort study of 192 patients C. Andrejak* (Amiens, France), O. Peuchant, N. Veziris, O. Segonds, D. Terru, F. Hamdad, A. Lagrange, V. Lalande, C. Laurain, P. Bemer P0897 Descriptive analysis of nontuberculosis mycobacteria isolated over a 5-year period at a general university hospital A. Vergara Gómez* (Barcelona, Spain), A. Lopez, J.C. Hurtado, G. Tudo, E. Polverino, J.A. Martinez, J. Gonzalez-Martin 182 24th ECCMID / Barcelona Final Programme Review of Tsukamurella spp. isolates in a tertiary hospital P. Falomir Salcedo* (Valencia, Spain), A. Gil-Brusola, B. Montull, A. Hernández-Cabezas, J.M. Molina, J.L. López-Hontangas 13:30 – 14:30 Poster Area POSTER SESSION III: Recent advances in molecular diagnosis of M. tuberculosis P0899 Experience with the implementation of Xpert MTB/RIF® assay in Rwanda, a low HIV/MDR-TB burden setting C. Muvunyi* (Huye, Rwanda), J.D. Birangwa, I. Uwimana, E. Kamazni, J.B. Mazarati P0900 Interest of the Xpert MTB/RIF® assay (CEPHEID) for the diagnosis of spondylodiscitis caused by Mycobacterium tuberculosis complex A. Dubouix Bourandy* (St. Jean, France), J. Duboureau, V. Pietri, J.L. Galinier, B. De Germay, J.M. Gandois P0901 Diagnostic accuracy of the Xpert MTB/RIF® assay according to clinical purpose H.J. Huh* (Seoul, Korea), K. Jeon, W.-J. Koh, Y.-Y. Hwang, C.-S. Ki, N.Y. Lee P0902 Evaluation of GeneXpert MTB/RIF® test performance for respiratory and nonrespiratory clinical samples A. Ilki* (Istanbul, Turkey), B. Aksu, R. Ayas, G. Soyletir P0903 Evaluation of TrueNAT with GeneXpert MTB/RIF® for rapid diagnosis of pulmonary tuberculosis C. NIKAM* (Mumbai, India), M. Kazi, C. Nair, A. Shetty, C. Rodrigues P0904 Development and evaluation of the detection of Mycobacterium tuberculosis complex on the BD MAX™ system in a European multicentre study I.O.M. Op den Buijs* (Veldhoven, The Netherlands), A.L. Seagar, P. Baltar, R.T.J.M. Roymans, K.E. Templeton, I.F. Laurenson, G. Barbeito, J.H.B. Van de Bovenkamp P0905 Large-scale evaluation of an integrated rapid molecular test of multidrug-resistant Mycobacterium tuberculosis in respiratory specimens T.C. Kwong, G.H.K. Siu* (Hong Kong, China), W.C. Yam Poster Sessions Sunday, 11 May 2014 Multi-centre evaluation of Speed-oligo® mycobacteria version 2 assay for identification of Mycobacterium spp. in routine clinical mycobacteriology M.J. Martinez-Lirola* (Almería, Spain), S. Hofmann-Thiel, J. Fernández Domínguez, M.J. Muñoz-Dávia, V. Cepas, S. Campos Gutierrez, M.J. Ruiz Serrano, M. Lecuona Fernández, F. Alcaide, M. Marín-Arriaza Evaluation of a new reverse hybridisationbased molecular method for detecting first- and second-line drug resistance in Mycobacterium tuberculosis in clinical samples B. Molina* (Badalona, Spain), A. Lacoma, C. Prat, E. Pimkina, J. Díaz, A. Dudnyk, J. Maldonado, S. Samper, J. Ruiz-Manzano, J. Domínguez P0916 Evaluation of the AID TB resistance line probe assay for rapid detection of genetic alterations associated with Mycobacterium tuberculosis drug resistance C. Ritter, K. Lucke, F.P. Maurer* (Zurich, Switzerland), F.A. Sirgel, R.W. Warren, P.D. Van Helden, E.C. Böttger, G.V. Bloemberg Comparison between PCR and culture as a diagnostic tool for pulmonary and extrapulmonary tuberculosis: seven years’ experience of a Portuguese infectious disease centre T. Azevedo* (Lisbon, Portugal), V. Moutinho, C. Lopes, T. Pacheco, R. Santos, J. Fernandes, S. Peres, F. Borges, K. Mansinho P0917 Use of a new multiplex PCR for the detection of Mycobacterium tuberculosis resistant to firstand second-line drugs in clinical strains and samples B. Molina* (Badalona, Spain), A. Lacoma, C. Prat, E. Pimkina, J. Díaz, J. Maldonado, S. Samper, J. Ruiz-Manzano, V. Ausina, J. Domínguez P0910 Improvement of patient care and impact on hospital finances by implementing a rapid PCR test for Mycobacterium tuberculosis complex R. Te Witt* (Rotterdam, The Netherlands), A. Luijendijk P0918 Low burden of rifampicin resistant TB lineages in Nepal using rapid PCR technique K. Moganeradj* (London, United Kingdom), P. Sonnenberg, I. Abubakar, T.D. McHugh, S. Khadge, D. Hagge, C. Arnold P0911 Application of multiplex PCR to routine diagnostics of tuberculosis and BCG-induced events in children M. Alvarez Figueroa* (Moscow, Russia), E. Dolgova, D. Levi P0919 P0912 Comparison of two nucleic acid amplification assays in comparison to culture for detection of Mycobacterium tuberculosis in respiratory specimens H. Al Helal, S. Al Johani* (Riyadh, Saudi Arabia) Systemic infections by Mycobacterium tuberculosis in HIV-positive patients as determined by direct molecular testing: influence of blood volume F. Bwanga, W. Worodria, A. Luyombya, I. Najjingo, L. Asege, T. Nalwoga, C. Disqué* (Bremen, Germany), M. Lorenz, V. Allerheiligen, M. Weizenegger P0920 A simple method based on a reliable genetic marker for identification of Mycobacterium tuberculosis Beijing genotype D. Fuentes, C. Villellas, M. Vitoria, S. Samper, J.A. Aínsa, L. Rodrigues* (Zaragoza, Spain) P0921 Application of the genotyping tool MIRU-VNTR to the analysis of Mycobacterium tuberculosis in the tuberculosis reference centre ‘University Hospital Virgen del Rocío’ (Seville, 2009-2013) V. Gonzalez Galan* (Seville, Spain), M.j. Torres, J. Aznar P0922 PCR separation of Mycobacterium intracellulare and Mycobacterium chimaera M.C. Muñoz Egea* (Madrid, Spain), J. Esteban, J.O. Falkinham P0913 P0914 Can we speed up TB diagnosis? Method development for mycobacterial DNA extraction and WGS from the first day positive liquid cultures A.A. Votintseva* (Oxford, United Kingdom), L.J. Pankhurst, T.M. Walker, C. Del Ojo Elias, D.H. Wyllie, A. Giess, T.E.A. Peto, D.W. Crook Evaluation of an array-based test for the detection of isoniazid and rifampicin resistance in Mycobacterium tuberculosis clinical strains and samples B. Molina* (Badalona, Spain), G. Kazdaglis, A. Lacoma, C. Prat, J. Díaz, J. Maldonado, S. Samper, J. Ruiz-Manzano, V. Ausina, J. Domínguez 24th ECCMID / Barcelona Final Programme Posters P0909 183 Chairs, Speakers & Authors P0908 P0915 Exhibition Performance comparison of two commercial tests for rapid molecular diagnosis of exprapulmonary tuberculosis in a low TB incidence country E.M. Mokaddas* (Dasma, Kuwait), H. Saadaldeen, S. Ahmad General Information P0906 Poster Sessions Sunday, 11 May 2014 P0923 Tuberculous sepsis in HIV-infected patients: modern possibilities of diagnostics V. Zhuravlev* (St.Petersburg, Russia), N. Soloveva, S. Mazokhina, E. Myakotina, T. Otten, M. Shulgina 13:30 – 14:30 P0925 P0926 P0927 P0928 P0929 P0930 Drug susceptibility pattern of Mycobacterium tuberculosis isolated from patients with pulmonary tuberculosis in Tripoli, Libya A.S. Albarouni* (Tripoli, Libya), N.B. Aboguttaia, W.M. Alamri, A.M. Fungi, M. Furjani, A. Zorgani Efflux as mechanism involved in antimicrobial resistance in clinical isolates of Mycobacterium tuberculosis T.S. Coelho, R.A. Maschmann, F.S. Spies, A. Von Groll, M. Viveiros, M.L.R. Rossetti, P.E. Almeida da Silva* (Rio Grande, Brazil) Mycobacterium tuberculosis spoligotypes and drug susceptibility pattern from tuberculosis patients in region of Macedonia-Thrace, Greece G. Kazdaglis* (Athens, Greece), B. Molina, G. Gioula, K. Manika, M. Gomes, L. Haba, D. Papaventsis, N. Malisiovas, J. Dominguez Effect of ciprofloxacin in the ultrastructure and development of biofilms formed by rapidly growing mycobacteria M.C. Muñoz Egea* (Madrid, Spain), M. García-Pedrazuela, J. Esteban Rapid detection of pyrazinamide-resistant Mycobacterium tuberculosis and characterisation of pncA gene mutations in Hong Kong T.C. Kwong* (Hong Kong, China), W.C. Yam An investigation of hydrophobicity and alphahelicity on the activities of synthetic cationic antimicrobial peptides in mycobacteria J.S. Khara* (Singapore, Singapore), F.K. Lim, P.L.R. Ee Combination of first-line anti-tuberculosis drugs and coated magnetite nanopoarticles against intrinsic resistance of Mycobacterium smegmatis P. Padwal* (Mumbai, India), R. Bandyopadhyaya, S. Mehra 184 24th ECCMID / Barcelona Polyclonality of non-pigmented rapidly growing mycobacteria (NPRGM): phenotypic and genotypic differences and their potential implications M. García-Pedrazuela, J.M. Frutos, M.C. Muñoz-Egea* (Madrid, Spain), F. Alcaide, T. Tórtola, A. Vitoria, P. Cortés, J. Esteban P0932 Association of genetic ancestry with Mycobacterium leprae genotypes in leprosy patients from Colombia N. Cardona-Castro* (Medellín, Colombia), J.C. Beltrán-Alzate, M. Romero, E. Cortés, G. Bedoya P0933 The predominance of subtype I among Mycobacterium kansasii clinical isolates from Poland, as evidenced by PCR restriction-enzyme analysis of the hsp65 gene Z. Bakula* (Warszawa, Poland), A. Safianowska, M. Nowacka-Mazurek, J. Bielecki, T. Jagielski P0934 Study of the effect of three drug combinations against susceptible and resistant M. tuberculosis using the time-killing curves method A. López Gavín* (Benavent de Segrià, Spain), G. Tudó Vilanova, J. González Martín, E. Rey Jurado P0935 Subspecies distribution, antibiotic susceptibility and genotypic resistance characteristics of Mycobacterium abscessus group J. Kim* (Seoul, Korea), H.S. Sung, J.S. Park, T.S. Shim, M.N. Kim P0936 Gene markers for predicting second-line antituberculosis drugs resistance T. Jagielski* (Warszawa, Poland), Z. Bakula, K. Roeske, M. Kaminski, A. Napiórkowska, R. Stachowiak, E. Augustynowicz-Kopec, J. Bielecki P0937 Polyclonal spread of antimicrobial resistant Mycobacterium tuberculosis and characterisation of resistance mutations in a university hospital, central Greece Z. Florou* (Larissa, Greece), A. Mavroidi, A. Vasdeki, A. Liakopoulos, Z. Garyfalopoulou, E. Petinaki P0938 Genetic diversity based on genomic deletion, polymorphisms and species specific mutations in first-line drug-resistant strains belonging to Mycobacterium tuberculosis complex (MTC) G. Fregni Serpini, A. Grottola, A. Fabio, S. Tagliazucchi, W. Gennari, F. Rumpianesi, M. Pecorari* (Modena, Italy) Poster Area POSTER SESSION III: Mycobacterial susceptibility and molecular epidemiology P0924 P0931 Final Programme Poster Sessions Comparison of clinical characteristics and treatment outcome of tuberculosis with diabetes mellitus, tuberculosis with human immunodeficiency virus and tuberculosis alone in tertiary care centre G. Suwanpimolkul* (Bangkok, Thailand), K. Kaewkittinarong, K. Ruxrungtham P0949 A clinical 11-year experience in peripheral tuberculous lymphadenitis A. Velo-Garcia* (Pontevedra, Spain), R. Brea Aparicio, A.E. Pena Graña, A. Pallarés Sanmartin, L. Anibarro P0950 Tuberculosis in patients treated with anti-TNF J.F. García-Rodríguez* (Ferrol, Spain), I. Gómez-Buela, C. Lijó-Carballeda, D. García-Alén, H. Álvarez-Díaz, A. Mariño-Callejo, M.V. Lorenzo-García P0951 Genitourinary tuberculosis: a review of 48 cases in Thailand P. Uppathamnarakorn* (Bangkok, Thailand), C. Suankratay POSTER SESSION III: Tuberculosis: clinical observations P0939 P0940 Epidemiology of admissions for Mycobacterium tuberculosis infection in Pavia, Lombardy, northern Italy, 2006-2013 L. Scudeller* (Pavia, Italy), A. Bonoldi, A. De Silvestri, T. Feletti, P. Marone, L. Pratico’, A. Muzzi, E. Seminari Tuberculosis in native residents and immigrants in the last twelve years in an area of northern Italy P. Brugnaro* (Biancade, Italy), F. Cattelan, E. Morelli, A. Petrucci, F. Cavinato, F. Eseme, V. Selle, S. Grandesso, E. Raise P0941 Changes in the epidemiology of mycobacterial respiratory infections in Murcia, Spain C. Candel Perez* (Murcia, Spain), C. Guerrero Gomez, C. Casañ Lopez, J. Bravo Urbieta, L. Lozano Garcia, R.m. Blazquez Garrido P0942 A cross-sectional study of pulmonary tuberculosis in a Libyan chest clinic in Misrata: differences among native and immigrant population M. Daw* (Sirte, Libya), B. Babitsch, C. Legault P0952 Osteoarticular tuberculosis: a case series of 118 patients from five French hospitals A. Guillouzouic, C. Andrejak, O. Peuchant, G. Héry-Arnaud, F. Hamdad, P. Lanotte, B. Olivero, M. Dupe, M. Valette, P. Bémer* (Nantes, France) P0943 Epidemiology of tuberculosis: investigation from three geographical areas in Greece F. Kontos, V. Mollaki, Z. Gitti, E. Petinaki, V. Liakou, E. Trikka-Graphakos, K. Paraskevi, K. Tsiveriotis, Z. Florou, L. Zerva* (Athens, Greece) P0953 Changes in ultrasound findings during treatment for HIV/TB co-infection M.T. Giordani* (Vicenza, Italy), E. Brunetti, C. Stecca, P. Benedetti, T. Heller P0954 Isoniazid preventive therapy for tuberculosis prevention in HIV patients: a retrospective study of Dilla University Referral Hospital HIV cohort H. Ayele* (Utrecht, The Netherlands), M. Bonten, M. Mourik P0955 Mycobacterium bovis in Burkina Faso, epidemiologic and genetic links between humans and cattle isolates A. Sanou, Z. Tarnagda, E. Kanyala, D. Zingué, M. Nouctara, H. Hien, A. Kabore, D. Neveu, A.-L. Bañuls, S. Godreuil* (Montpellier, France) Latent tuberculosis infection: what have we been able to do so far? F. Sanchez* (Barcelona, Spain), L. Moro, G. Orduna, R. Oanea, N. Jové, J.P. Horcajada P0956 Extrapulmonary tuberculosis during course of fever of unknown origin G. Stevanovic* (Belgrade, Serbia), L. Lavadinovic, A. Spurnic-Radovanovic, M. Ilic, T. Kokotovic, M. Pelemis Sulfamethoxazole as a treatment option for drugresistant tuberculosis L.M. Davies Forsman* (Stockholm, Sweden), T. Schön, M. Larsson, P. Juréen, C.G. Giske, J. Bruchfeld, U. Simonsson, K. Angeby P0957 Fixed-dose combination drugs in tuberculosis treatment and control J.F. García-Rodríguez* (Ferrol, Spain), I. Gómez-Buela, C. Lijó-Carballeda, H. Álvarez-Díaz, A. Mariño-Callejo, P. Sesma-Sánchez P0945 P0946 P0947 Epidemiology of Mycobacterium bovis disease in humans, France, 2000-2010 M. Choisy, M.L. Boschiroli, J. Maugein, C. Segonds, M.L. Abalain, V. Jacomo, M. Ponsada, G. Panteix, A.L. Bañuls, S. Godreuil, N. Bouzinbi* (Montpellier, France) 24th ECCMID / Barcelona Final Programme 185 Chairs, Speakers & Authors P0948 Exhibition Poster Area General Information 13:30 – 14:30 Posters Sunday, 11 May 2014 Poster Sessions Sunday, 11 May 2014 P0958 Out of pocket costs for patients with tuberculosis in Colombia: evidence from three metropolitan areas J.M. Hernandez Sarmiento* (Medellin, Colombia), L. Martinez, J. Cardona, E. Jimenez, L. Mejia, Y. Sanchez, L. Ochoa, G. Gonzalez, C. Lazaro P0959 Bilateral vitritis as a complication of intravesical BCG immunotherapy N. Elsakka, V. Bateman, G. Hepburn, L. Kuffova, D. O’Brien* (Aberdeen, United Kingdom) P0960 Prescriptions and dispensing of rifampicin products for tuberculosis in Norway: a retrospective study T. Westergren* (Oslo, Norway), A. Falck, G. Gadeholt, E. Lingaas 13:30 – 14:30 P0961 MGIT™ times to positivity in the REMoxTB study: evidence for reducing the MGIT™ incubation time M.E. Murphy* (London, United Kingdom), A. Bateson, T.D. McHugh, S.H. Gillespie P0962 Evaluation of a new generation of an acid-fast bacilli aerospray automated slide stainer for direct sputum smears K. Mullen* (Logan, United States), E. Shipiki, C. Helme Comparison of the BD TB Fluorescent Stain Kit T and RAL stainer system in staining smears from pulmonary specimens: quality and time study C. Cavusoglu* (Izmir, Turkey), A. Aslan P0964 Validation of Copan Myco-TB and Myco-TB kit for rapid digestion and decontamination of clinical specimens for the detection of MTB with all testing methods E. Mazzola* (Brescia, Italy), A. Nava, M. Delle Canne, S. Castriciano, G. Gesu P0965 Molecular detection of Mycobacterium tuberculosis from formalin-fixed, paraffinembedded tissues H. Al Ghazal, S. Al Johani* (Riyadh, Saudi Arabia) 186 24th ECCMID / Barcelona Can serum siderocalin levels predict active tuberculosis in HIV-infected and non-HIV-infected individuals? G.M. Varghese* (Vellore, India), V.P. Turaka, J. Janardhanan, T.S. Vijayakumar, B. Cherayil P0967 Endobronchial ultrasonography-guided transbronchial needle aspiration (EBUS-TBNA) for the diagnosis of mediastinal tuberculosis J.B. Stern* (Paris, France), R. Caliandro, P. Validire, B. Wyplosz, L. Escaut, G. Lorillon, D. Gossot P0968 Rational application of adenosine deaminase activity in cerebrospinal fluid for the diagnosis of tuberculous meningitis V. Ramos, D. Vinuesa, V. Portillo-Tuñón, N. Coronado-Álvarez, F. Anguita-Santos, R. Cabo-Magadán, L. Muñoz-Medina, C. Dueñas, J. Parra Ruiz* (Granada, Spain), J. Hernández-Quero P0969 QuantiFERON-Gold TB In-Tube assay – a critical reassessment of results in a low prevalence setting (Thuringia, Germany) B. Hermann* (Jena, Germany), M. Baier P0970 Interferon-gamma and tumoural necrosis factor-alpha gene polymorphisms in pulmonary tuberculosis: performance in TB-endemic indigenous population Z. Araujo García* (Caracas, Venezuela), A. Palacios, R. Biomón, I. Rodríguez, J. Jiménez, A. Wide P0971 A pilot study measuring the kinetic profile of IP-10 over the first 14 days of pulmonary tuberculosis chemotherapy R. Saunders* (Liverpool, United Kingdom), M. Blakiston, L. Lawson, G. Harper, R. Anthony, L.E. Cuevas P0972 Distribution of killer cell immunoglobulin-like receptors’ genes in patients with pulmonary tuberculosis from northern Spain J.G. Ocejo-Vinyals, C. González Rico, F. Ausín, E. Puente de Mateo, J.L. Arroyo, R. Agüero, M.C. Fariñas* (Santander, Spain) Poster Area POSTER SESSION III: Tuberculosis: non-molecular diagnosis and pathogenesis P0963 P0966 Final Programme Poster Sessions Monday, 12 May 2014 P0982 Emergence of fluoroquinolone resistance amongst three species of Haemophilus isolated in a clinical laboratory N. Liassine* (Geneva, Switzerland), K. Baroli, O. Gaillot P0983 Global prevalence, genetics and clonal relatedness of macrolide resistance in Moraxella catarrhalis (2010-2012) D.J. Farrell* (North Liberty, IA, United States), A.J. Costello, M. Castanheira, R.N. Jones POSTER SESSION IV: Molecular epidemiology of Haemophilus, Moraxella, and Neisseria P0975 Dynamics of Neisseria gonorrhoeae population J. Serra Pladevall* (Barcelona, Spain), G. Roig, R. Juve, J.J. Gonzalez, R. Bartolome, M.J. Barbera, A. Andreu P0976 P0977 P0978 Drug resistance in Neisseria gonorrhoeae due to disorder in outer membrane proteins E. Ilina* (Moscow, Russia), M. Malakhova, I. Bodoev, O. Pobeguts, I. Altukhov, E. Khlebus, S. Kovalchuk, V. Govorun Beta-lactams plasmid-mediated resistance in Neisseria gonorrhoeae in France M. Michaelo, H. Jacquier, E. Cambau, A. Goubard, P. Sednaoui, G. La Ruche, B. Bercot* (Paris, France) Molecular epidemiology of quinolone resistance in Neisseria gonorrhoeae in France D. Gueret, T. Guillard, B. Bercot* (Paris, France), G. La Ruche, A. Goubard, P. Sednaoui, E. Cambau P0979 Phylogenetic diversity of ST4821 complex of Neisseria meningitidis isolated from 1965 to 1985 and 2005 to 2013 in Shanghai, China Q. Guo* (Shanghai, China), M. Chen, M. Chen, M. Wang P0980 Clinical and molecular epidemiology of Haemophilus influenzae causing invasive disease in adult patients C. Puig Pitarch* (Hospitalet de Llobregat, Spain), I. Grau, S. Marti, R. Pallares, C. Ardanuy, J. Liñares P0981 Characterisation of ampicillin-resistant Haemophilus influenzae isolates in middle ear fluid from Japanese children with acute otitis media R. Kakuta* (Sendai, Japan), H. Yano, H. Hidaka, M. Ogawa, A. Tanouchi, D. Ozawa, S. Endo, H. Kanamori, M. Kaku, Y. Katori 12:30 – 13:30 Poster Area POSTER SESSION IV: Molecular epidemiology and surveillance of MDR Pseudomonas and Acinetobacter P0984 Carbapenem-resistant Pseudomonas aeruginosa disseminated in Centro Hospitalar do Baixo Vouga, Aveiro, Portugal C. Santos* (Aveiro, Portugal), S. Ferreira, E. Ramalheira, S. Mendo P0985 Genetic diversity and antibiotic susceptibility of Pseudomonas aeruginosa isolated from patients, healthy volunteers and domestic animals in Estonia K. Telling* (Tartu, Estonia), V. Kisand, S. Kõljalg, P. Kalmus, M. Maimets, I. Lutsar, T. Tenson P0986 Epidemiological characterisation of class 1 integrons isolated in multidrug-resistant Acinetobacter spp. in a tertiary hospital in Daejeon, Korea for seven years S. Koo* (Daejeon, Korea), G. Sung, G. Kwon, J. Kim, J. Lim P0987 Characterisation of intrinsic beta-lactam resistance mechanisms among contemporary ceftazidime non-susceptible Pseudomonas aeruginosa from USA hospitals M. Castanheira* (North Liberty, IA, United States), J.C. Mills, R.E. Mendes, R.N. Jones P0988 Analysis of metallo-beta-lactamase-encoding class 1 integrons in Pseudomonas aeruginosa isolates from the UK L.L. Wright* (London, United Kingdom), J.F. Turton, D.M. Livermore, K.L. Hopkins, N. Woodford 24th ECCMID / Barcelona Final Programme 187 Posters Molecular typing by NG-MAST of Neisseria gonorrhoeae isolated from recurrent genital infections M. Gits-Muselli, B. Bercot* (Paris, France), F. Lassau, M. Janier, E. Cambau Chairs, Speakers & Authors P0974 Exhibition Poster Area General Information 12:30 – 13:30 Poster Sessions Monday, 12 May 2014 P0989 Carbapenem-resistant Acinetobacter baumannii with OXA-72 carbapenemase and extendedspectrum beta-lactamase CTX-M-2 Y. Pfeifer* (Wernigerode, Germany), G. Werner, K.P. Hunfeld, D. Maneg, S. Borgmann, W. Blobner, P.G. Higgins P0990 Prevalence of colistin-resistant Acinetobacter spp. isolates in Centro Hospitalar entre Douro e Vouga, Santa Maria da Feira, Portugal C. Santos* (Aveiro, Portugal), A. Viana, A. Silva, S. Mendo P0991 Molecular characterisation of carbapenemresistant Acinetobacter baumannii isolates from bloodstream infections from 15 university hospitals in the republic of Korea M.J. Kim* (Seoul, Korea), J.Y. Kim, J.Y. Kim, J.W. Sohn, D.W. Park, Y.K. Yoon, C.S. Lee, S.Y. Ryu, M.S. Lee, S.S. Lee P0992 Molecular epidemiology of Acinetobacter spp. causing bacteraemia in Japanese community hospitals S. Endo* (Sendai, Japan), H. Yano, H. Kanamori, S. Inomata, T. Aoyagi, M. Hatta, Y. Gu, K. Tokuda, M. Kitagawa, M. Kaku P0993 Emergence and spread of blaNDM-1 along with blaOXA-23 among Acinetobacter baumannii clinical isolates from Egypt M. Abdelgawad, M. Ali Amin, W. Tawakol, L. Loucif, J.M. Rolain* (Marseille, France) P0994 Identification of particular clonal complexes and mobile elements associated with the dissemination of blaOXA-23-carrying Acinetobacter baumannii and blaVIM-2-carrying Pseudomonas aeruginosa in Romania I. Gheorghe* (Bucharest, Romania), A. Novais, F. Grosso, C. Rodrigues, C. Chifiriuc, V. Lazar, L. Peixe P0995 Species distribution, clonal diversity and antimicrobial susceptibility of Burkholderia cepacia complex isolates from cystic fibrosis patients in Barcelona A. Mirambell Viñas* (Barcelona, Spain), M. Lung, T. Cornejo-Sánchez, M.A. Cano, A. Ferrer, R. Bartolomé, M.N. Larrosa, J.J. González-López P0996 The critical role of molecular surveillance in control of Acinetobacter baumannii infections O. Ergonul* (Istanbul, Turkey), E. Donmez, C. Seref, A. Komur, P. Ispir, D. Egeli, T. Kafadar, F. Can 188 24th ECCMID / Barcelona Final Programme P0997 Carbapenem-resistant Acinetobacter baumannii harbouring OXA-type (OXA-24-, OXA-58- and OXA143-like) carbapenemases in Brazil T.P.G. Chagas* (Rio de Janeiro, Brazil), I.C.O. Santos, A.P.D.’A. Carvalho-Assef, M.D. Asensi P0998 Molecular epidemiology, carbapenem and colistin susceptibility of Acinetobacter baumannii isolated as part of the MagicBullet clinical trial P. Higgins* (Cologne, Germany), J. Nowak, E. Zander, I. Roca, J. Vila, H. Seifert P0999 Molecular epidemiology of carbapenem-resistant Acinetobacter baumannii isolated in intensive care units D. Haciseyitoglu, Y. Cag* (Istanbul, Turkey), O. Ak, S. Gencer, G. Akengin Ocal, F. Biteker, Z. Gurkan, S. Ozer P1000 Impact of carbapenem-resistant Acinetobacter baumannii healthcare-associated infections in patients admitted to Italian intensive care units: results of the SPIN-UTI cohort study A. Agodi* (Catania, Italy), F. Auxilia, M. Barchitta, M.M. D’Errico, M.T. Montagna, C. Pasquarella, S. Tardivo, I.I. Mura, G. S.I.t.I. P1001 A case-control study to identify predictors of 14-day mortality following carbapenem-resistant Acinetobacter baumannii bacteraemia A. Nutman* (Tel Aviv, Israel), R. Glick, E. Temkin, M. Hoshen, R. Edgar, T. Braun, Y. Carmeli P1002 ICU-acquired pneumonia due to Pseudomonas aeruginosa with and without multidrug resistance: specific risks factors and associated inflammatory response L. Fernandez-Barat* (Barcelona, Spain), F. De Rosa, M. Ferrer, A. Gabarrús, M. Esperatti, S. Terraneo, M. Rinaudo, L.F. Difrancesco, G. Li Bassi, A. Torres P1003 Risk factors and influence of carbapenem exposure on the development of carbapenem resistant Pseudomonas aeruginosa bloodstream infections M. Barron* (Aurora, United States), K. Richardson, B. McCollister P1004 Molecular characterisation of Pseudomonas aeruginosa and Enterobacteriaceae isolates harbouring the carbapenemase GIM-1 A. Hamprecht* (Cologne, Germany), S. Göttig, L. Poirel, S. Gatermann, H. Seifert, M. Kaase Poster Sessions Carbapenem-resistant Acinetobacter baumannii in adult intensive care unit: risk factors for colonisation and infection N. Aksu, I. Baran, M.A. Yetkin* (Ankara, Turkey), D. Kanyilmaz, I. Mumcuoglu, A. Bastug, S. Alacam, H. Yagmurdur, H. Bodur 12:30 – 13:30 Poster Area Natural distribution of transmissible beta-lactams resistance mechanisms in Enterobacteriaceae A. Xiaoman, A. Fajardo-Lubian* (Sydney, Australia), A. Agyekum, A. Ginn, J. Iredell P1013 Diverse Salmonella non-typhoid antibioticresistant clonal lineages are tolerant to copper and silver metals J. Mourão* (Porto, Portugal), J. Machado, C. Novais, L. Peixe, P. Antunes P1014 Replicon typing of Enterobacter cloacae complex isolates producing extended-spectrum betalactamases (ESBL) from northern Spain J. Calvo Montes* (Santander, Spain), E. Román Paucar, M.P. Garcillán Barcia, M.E. Cano García, A. Ocampo Sosa, B. Ruiz del Castillo, L. Martínez Martínez P1015 Detection of class 1, 2, and 3 integrons among extended-spectrum beta-lactamase-producing Klebsiella pneumoniae isolated from Baltic sea region K. Pärna, A. Balode A- Edquist P- Egorova S- Kaftyreva L – Miciuleviciene J, M. Ivanova, S. Kõljalg, K. Pai, A. Pavelkovich, T. Rööp, E. Sepp, P. Naaber, J. Stsepetova* (Tartu, Estonia) P1016 Relatively high prevalence of genetic and phenotypic silver resistance among Enterobacter cloacae isolates S. Sütterlin* (Uppsala, Sweden), Y. Molin, A. Melhus P1017 Characterisation of outer-membrane proteins and carbapenemase in carbapenem-resistant Enterobacter aerogenes and Enterobacter cloacae J.R. Ferraz, J. Calil, C. Rizek, C. Carrilho, S. Costa* (Rio de Janeiro, Brazil) P1018 Molecular characterisation of carbapenemases amongst non-susceptible Enterobacteriaceae isolated from South African hospitals: 1 October 2012 – 1 October 2013 J. Coetzee* (Pretoria, South Africa), A.J. Brink, C. Corcoran, T. Marshall, C. Sriruttan, C. Clay P1019 Characterisation of CTX-M-14-and CTX-M-15producing Escherichia coli and Klebsiella pneumoniae isolates from urine specimens in a tertiary hospital S. Koo* (Daejeon, Korea), S. Kim, G. Kwon, J. Kim POSTER SESSION IV: Molecular epidemiology of MDR Enterobacteriaceae P1007 Investigating antimicrobial resistance in soil-culturable Gram-negative bacteria D. Jones-Dias* (Lisbon, Portugal), E. Ferreira, J. Almeida, M. Caniça P1008 Resistance genes to aminoglycosides [aac(6?)Ib-cr, aac(3)-IIa, aadA], quinolones (qnrB) and integrons in multirresistant KPC-producing Klebsiella pneumoniae from Brazil P. Silva Pereira* (Rio de Janeiro, Brazil), M. Borghi, M. Dutra Asensi, A.P. D’Alincourt Carvalho Assef P1009 Sensitivity and specificity of the MIC test strips (MTS) mechanisms of detection against in-house methods for 644 multi-drug resistant (MDR) strains: a European multi-centre study R. Canton, M. Gniadkowski, M. Morosini, M. Pirs, G. Rossolini, M. Sukhorukova, A. Tsakris, G. Vrioni, T. Walsh* (Cardiff, United Kingdom), D. Zabicka P1010 P1011 Prevalence of 16S rRNA methylase genes in enterobacterial isolates in two Greek hospitals in a three-year period I. Galani, H. Moraitou, K. Orlandou, K. Nafplioti, M. Drogari-Apiranthitou, E. Vogiatzakis, G. Petrikkos* (Athens, Greece), M. Souli Recent dissemination of a GIM-1-producing Serratia marcescens clone in North Rhine Westphalia, Germany A.F. Wendel* (Düsseldorf, Germany), H. Rieber, C.R. MacKenzie 24th ECCMID / Barcelona Final Programme 189 Chairs, Speakers & Authors P1006 P1012 Exhibition KPC-producing Pseudomonas aeruginosa from the United States: what next? L.M. Deshpande, K.M. Simpson, R.N. Jones, M. Castanheira* (North Liberty, IA, United States) General Information P1005 Posters Monday, 12 May 2014 Poster Sessions Monday, 12 May 2014 P1020 Carbapenemase-producing Gram-negatives in Colombia, between 2012 and 2013 S. Saavedra Rojas* (Bogota, Colombia), C. Duarte, M. Gonzalez, M. Ovalle, A. Villalobos, S. Rivera, M. Beltran, L. Barrero P1021 ESBL-producing E. coli and K. pneumoniae: is the community a reservoir of widespread clones or clonal variants? J. Pires* (Porto, Portugal), C. Rodrigues, R. Campainha, S. Moniz, J. Amorim, L. Peixe, Â. Novais P1043 P1022 P1023 P1024 P1025 P1021a P1026 Correlation between antimicrobial consumption in the intensive care unit and resistance of some bacteria involved in pulmonary infections in hospitalised patients S. El Mais* (Craiova, Romania), L. Rosu, D. Calina, A. Turculeanu, A. Rosu, O. Zlatian P1027 The first detection of plasmid-mediated AmpC beta-lactamase in multidrug-resistant Proteus mirabilis isolates from University Hospital Centre Split, Croatia Z. Rubic* (Split, Croatia), S. Soprek, M. Jelic, M. Radic, A. Novak, I. Goic-Barisic, M. Tonkic, A. Tambic-Andrasevic P1028 Association of plasmid-mediated AmpC and extended-spectrum beta-lactamase in Klebsiella pneumoniae isolated at Charles Nicolle Hospital of Tunis, Tunisia T. Chérif, M. Saidani, A. Kammoun, R. Ghozzi, I. Boutiba* (Tunis, Tunisia), A. Slim P1029 Investigation of virulence potential of the ESBLproducing Klebsiella pneumoniae strains isolated from Bulgarian hospitals D. Ivanova* (Sofia, Bulgaria), R. Markovska, I. Mitov P1030 Detection of NDM-1- carbepenemase in Providencia rettgeri isolates from 5 hospitals of two cities in Colombia S. Saavedra Rojas* (Bogota, Colombia), C. Duarte, M. Gonzalez P1031 Co-association of blaNDM-1 and blaKPC-2 in Brazilian Enterobacteriaceae clinical isolates M.G. Quiles* (São Paulo, Brazil), T.T. Rocchetti, L.C. Fehlberg, E.J.U. Kusano, A. Chebabo, R.M.G. Pereira, A.C. Gales, A.C.C. Pignatari Emergence and spread of a novel carbapenem resistance plasmid in a hospital cohort involving multiple species of Enterobacteriaceae A.E. Sheppard* (Oxford, United Kingdom), A. Giess, N. Stoesser, A. Bashir, R. Sebra, A. Kasarkis, D.W. Crook, C.D. Sifri, A.J. Mathers P1032 Genetic determinants of antimicrobial resistance, virulence factors and plasmid content in multidrug-resistant Klebsiella pneumoniae from four large hospitals in Brazil L.N. Andrade* (São Paulo, Brazil), L.M.M. Stegani, A.L.C. Darini Carbapenemase and pathogenicity of Enterobacteriaceae in north Lebanon between 2008 and 2012: towards an endemic diffusion of OXA-48 R. Beyrouthy* (Clermont Ferrand, France), F. Robin, F. Dabboussi, H. Mallat, M. Hamzé, R. Bonnet P1033 Resistance plasmids in ESBL-producing Klebsiella pneumoniae J.B. Nielsen* (Hvidovre, Denmark), L.H. Hansen, K. Schønning P1034 Duration of hospitalisation in South African healthcare facilities prior to the acquisition of carbapenemase-producing Enterobacteriaceae (CPE) A. Brink* (Johannesburg, South Africa), J. Coetzee, C. Corcoran, T. Marshall, C. Sriruttan, C. Clay ESBL-producing Enterobacteriaceae other than E. coli in Portuguese hospitals: the spread of epidemic K. pneumoniae clones and plasmids (IncR, IncFIIK, IncL/M) C. Rodrigues* (Porto, Portugal), E. Machado, L. Peixe, Â. Novais Molecular survey of 2109 carbapenem-resistant Enterobacteriaceae isolates from Portuguese hospitals: co-production of carbapenemase KPC3 and the efflux pump OqxAB V. Manageiro* (Lisbon, Portugal), E. Ferreira, J. Almeida, S. Barbosa, C. Simões, Antimicrobial Resistance Surveillance Program in Portugal, M. Caniça Outbreak of Salmonella enterica serovar Infantis harbouring CTX-M-9-group extended-spectrum beta-lactamase (ESBL) in children less than 6 years old with diarrhoea in Lima, Peru M. Riveros Ramirez* (Lima, Peru), A. Granda Alacote, K. Ocampo Cardenas, S. Martínez Puchol, A. Corujo Fernandez, J. Ruiz, I. Reyes, T. Ochoa Acquisition of ESBL- and carbapenemaseproducing Enterobacteriaceae in a large prospective cohort of healthy travellers: the Carriage Of Multiresistant Bacteria After Travel (COMBAT) study M.S. Arcilla, J.M. Van Hattem* (Rotterdam, The Netherlands), P.J. Van Genderen, A. Goorhuis, C. Schultsz, E.E. Stobberingh, H.A. Verbrugh, M.D. De Jong, D.C. Melles, J. Penders 190 24th ECCMID / Barcelona Final Programme Poster Sessions P1038 P1039 P1040 P1041 P1042 Increasing multidrug resistance in Gram-negative bacteraemia: trends over 13 years in a teaching hospital in London C. Suarez Fernandez* (London, United Kingdom), L. Whitney, A. Breathnach, T. Planche P1045 Per-like extended-spectrum beta-lactamaseproducing Acinetobacter baumannii in Kuwait A. Dashti* (Kuwait City, Kuwait), L. Vali, A. Opazo, K. Al- Obaidi, S. Amyes P1046 Prevalence of colonisation by ESBL-producing enterobacteria in patients with Clostridium difficile infection M. Arvand* (Dillenburg, Germany) P1047 Genetic characterisation of KPC-2 producing Klebsiella pneumoniae and polymixin B resistance from several hospitals in São Paulo state, Brazil G. Francisco* (São Paulo, Brazil), M.F. Bueno, Y. Doi, D.O. Garcia P1048 Molecular epidemiology and characteristics of extended-spectrum beta-lactamase-producing Escherichia coli in the Japanese clinical setting H. Yano* (Sendai, Japan), A. Tanouchi, S. Endo, H. Kanamori, T. Aoyagi, M. Hatta, Y. Gu, K. Tokuda, M. Kitagawa, M. Kaku Bacteraemia due to extended-spectrum beta-lactamase (ESBL) / AmpC-positive Enterobacteriaceae in hospitalised patients at Basildon and Thurrock University Hospitals: molecular, microbiological and clinical characterisation S.G. Udugama* (Essex, United Kingdom), B.P. Cherian, D. Wareham, M. Parker P1049 Distribution of extended-spectrum betalactamase (ESBL)-positive Enterobacteriaceae in hospitals throughout Germany R. Leistner* (Berlin, Germany), C. Schröder, A.C. Breier, C. Geffers, P. Gastmeier, M. Behnke Emergence of E. coli O25b-ST131 clone among uropathogenic multidrug-resistant isolates and associated clinical risk factors F. Can, C. Seref* (Istanbul, Turkey), P. Ispir, I. Loclar, O. Kurt-Azap, O. Ergonul P1050 Bloodstream infections caused by ESBLproducing Escherichia coli: epidemiology and clinical features S. Cho* (Seoul, Korea), C.I. Kang, M. Cha, W.J. Lee, D.R. Chung, N.Y. Lee, K.R. Peck, J.H. Song Characterisation of Escherichia coli carrying blaNDM-7 from the Sultanate of Oman A. Sonnevend* (Al Ain, United Arab Emirates), A. Ghazawi, D. Darwish, L. Villa, A. Carattoli, A. AlJardani, S. Al-Abri, T. Pál P1051 Molecular characterisation of KPC-producing Klebsiella pneumoniae from Belgium C. Bauraing* (Yvoir, Belgium), P. Bogaerts, A. Deplano, W. Boucharhouf, T.D. Huang, B. Jans, O. Denis, Y. Glupczynski Molecular characterisation of New Delhi metallo-beta-lactamase-1 and it variants among Enterobacteriaceae from India K.N. Prasad* (Lucknow, India), M. Rahman, S.K. Shukla, C.M. Ovejero, B. Pati, A. Tripathi, A. Singh, B.G. Zorn Report of the national reference laboratory for multidrug-resistant Gram-negative bacteria on carbapenemases in Germany in 2013 M. Kaase* (Bochum, Germany), A. Anders, N. Pfennigwerth, S.G. Gatermann The epidemiology of extended-spectrum betalactamase-producing Klebsiella pneumoniae that contain qnr genes in Kuwait A.A. Dashti* (Kuwait City, Kuwait), L. Vali, M.M. Jadaon, S. El-Shazly The mother provides an important risk factor for colonisation of neonates with extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-E) L.A. Denkel* (Berlin, Germany), F. Schwab, B. Piening, A. Kola, C. Geffers, L. Garten, K. Von Weizsäcker, P. Gastmeier Chairs, Speakers & Authors P1037 P1044 Exhibition P1036 Prevalence and clinical characteristics of hypermucoviscous Klebsiella pneumoniae causing bacteraemia among adult patients in a teaching hospital in Barcelona M. Cubero* (L’Hospitalet de Llobregat, Spain), I. Grau, F. Tubau, R. Pallarés, M.A. Domínguez, J. Liñares, C. Ardanuy 24th ECCMID / Barcelona Final Programme 191 General Information P1035 Posters Monday, 12 May 2014 Poster Sessions Monday, 12 May 2014 Poster Area P1060 Are urinary isolates more resistant than nonurinary isolates? M.M. Soriano* (Chicago, United States), A.T. Harrington, L.H. Danziger P1052 Study to estimate the burden of ESBL E. coli and Klebsiella species causing community-acquired urinary tract infections in Tower Hamlets borough of London G. Jacob* (London, United Kingdom), S. Das P1061 ESBL production is a common independent risk factor for colonisation/infection by Escherichia coli with phenotypic heterogeneous resistance to carbapenems L. Zhang* (Chongqing, China), J. Sun, S. Huang, S. Pu, L. Zheng, C. Zhang P1053 Low prevalence of extended-spectrum betalactamase (ESBL)-producing Escherichia coli in community-acquired urinary tract infections in Uppsala county, Sweden M. Ericsson* (Uppsala, Sweden), A. Lindström, G. Stridh Ekman, O. Andersson, S. Susanne P1062 The effect of different quinolone groups on selection of quinolone-resistant Escherichia coli in faecal flora Z. Bayindir* (Ankara, Turkey), G. Aydin, F. Yoruk P1063 Use of pivmecillinam for treating urinary tract infection caused by multidrug-resistant Enterobacteriaceae P. Hunter, F. Christison, J. McLaren, K. McCandless, S. McCormick, D. Inverarity* (Airdrie, United Kingdom), S.J. Dancer P1064 Fosfomycin-resistant Escherichia coli causing urinary tract infection (UTI) A. Rando* (Barcelona, Spain), N. Larrosa, L. Goterris, E. Garcia, Z. Moure, E. Dueñas, C. Gulín, A. Andreu, D. Viu P1065 Clinical and microbiological outcomes after cefoxitin treatment for infections caused by extended-spectrum-beta-lactamase-producing Enterobacteriaceae: results of an observational study S. Kernéis* (Paris, France), S. Valade, G. Geri, F. Compain, M. Lavollay, H. Rostane, E. Carbonnelle, J. Mainardi 12:30 – 13:30 POSTER SESSION IV: Resistance surveillance in Gram-negatives P1054 Prevalence of ESBL-producing E. coli and K. pneumoniae in Georgia 2011-2012 T. Davitashvili, N. Jashiashvili* (Tbilisi, Georgia) P1055 Epidemiology and susceptibility of pathogens from hospital- and community-associated urinary tract infection in Turkey: SMART 2011-2012 S. Lob, G. Yilmaz, P. Zarakolu, L. Mulazimoglu, B. Mete, Z. Gülay, R. Badal* (Sacramento, CA, United States), S. Bouchillon, M. Hackel, And the Turkish SMART Study Group P1056 Risk factors for community-onset urinary tract infection caused by extended-spectrum betalactamase-producing bacteria in adults E. Koksal, N. Tulek* (Cankaya, Ankara, Turkey), F. Temocin, C. Bulut, C. Ataman Hatipoglu, F.S. Erdinc, G. Tuncer Ertem P1057 Antibiotic susceptibility profiles of urinary Escherichia coli isolates and community antibiotic use in Tasmania, Australia E. Meumann* (Hobart, Australia), L. Cooley, A. McGregor, B. Mitchell P1066 Survey of extended-spectrum beta-lactamase (ESBL) producing Escherichia coli strains in the French community (2008-2012) S. Thibaut, A. Marquet, M. Lagneau, J.F. Huon, G. Grandjean, J. Caillon* (Nantes, France), F. Ballereau, & medical analysis laboratories of MedQual network Isolation of extraintestinal pathogenic E. coli from postcholecystectomic samples and their antimicrobial resistance profile in Georgia E. Vashakidze* (Tbilisi, Georgia), T. Megrelishvili, E. Pachkoria, P. Imnadze, L. Tevzadze, G. Chanturia, T. Tevdoradze, N. Khachidze P1067 Presence of multiresistant Enterobacteriaceae in university hospital wastewater M. Htoutou Sedlakova* (Olomouc, Czech Republic), V. Husickova, R. Silova, P. Imwensi, M. Roderova, J. Bardon, M. Kolar P1068 Five year analysis (2009-2013) of the identification and antimicrobial susceptibility trends for Enterobacter spp. collected from EU countries in the test programme D. Biedenbach* (Schaumburg, United States), S. Bouchillon, M. Hackel, I. Morrissey P1058 P1059 Extended-spectrum beta-lactamase and quinolone-resistant Escherichia coli in acute prostatitis: a study of 11345 cases of transrectal ultrasound (TRUS)-guided prostate biopsy H.G. Jeon, W. Song, H.W. Moon* (Seoul, Korea), B.C. Jeong, S.I. Seo, S.S. Jeon, H.M. Lee, H.Y. Choi 192 24th ECCMID / Barcelona Final Programme Poster Sessions Tigecycline activity tested against carbapenemresistant Enterobacteriaceae from European hospitals: results from the SENTRY program (2010-2013) H.S. Sader* (North Liberty, IA, United States), M. Castanheira, D.J. Farrell, R.K. Flamm, R.N. Jones P1072 P1073 Nationwide multicentric survey on multidrugresistant Pseudomonas aeruginosa isolates in Belgian hospitals in 2012-2013 Y. Glupczynski* (Yvoir, Belgium), C. Berhin, A. Deplano, C. Bauraing, T.-D. Huang, B. Jans, O. Denis, P. Bogaerts P1080 Prevalence of metallo-beta-lactamases in carbapenem non-susceptible Pseudomonas aeruginosa isolates in south east Austria E. Leitner* (Graz, Austria), A. Badura, M. Hoenigl, M. Gehrer, J. Luxner, L. Masoud-Landgraf, U. WagnerEibel, G. Feierl, A. Grisold P1081 Stability of ertapenem MICs of Escherichia coli in Europe: SMART 2008-2012 S. Lob, R. Badal* (Sacramento, CA, United States), S. Bouchillon, M. Hackel, D. Hoban High level of antimicrobial resistance of Pseudomonas spp. isolates in a haematology unit compared with the intensive care unit and other hospital units in Saragossa, Spain A.I. López-Calleja, I. Ferrer, L. Alcalá, P. Delgado, M.C. Villuendas, P. Palacián, G. Martin, M.J. Revillo, A. Rezusta* (Zaragoza, Spain) P1082 Prevalence and antibiotic susceptibility of ESBLpositive pathogens: an evaluation of SMART data 2011-2012 from Lebanon compared to regional Middle East A. Hajj* (Beirut, Lebanon), L. Kazan, D. Karam Sarkis Epidemiology and susceptibility of pathogens from intra-abdominal infections in different patient settings in Turkey: SMART 2011-2012 S. Lob, I. Koksal, S. Unal, V. Korten, F. Tabak, E. Alp, V. Oguz, R. Badal* (Sacramento, CA, United States), M. Hackel, And the Turkish SMART Study Group P1083 Resistance of bacteria isolated from clinical samples in hospitalised patients in the burns unit and plastic surgery ward in a Greek hospital during five years M. Orfanidou* (Athens, Greece), M. Kamperogianni, A. Karonidis, G. Ganteris, L. Drosopoulou, D. Tsoutsos, E. Vagiakou, H. Malamou-Lada P1084 Comparison of CLSI and EUCAST clinical breakpoints for surveillance of antimicrobial resistance of Salmonella enterica in Bulgaria, 2011-2012 G. Asseva* (Sofia, Bulgaria), I. Tomova, K. Ivanova, I. Ivanov, E. Dobreva, B. Panova, P. Petrov, T. Kantardjiev P1085 Differences in bacterial resistance observed among pathogens collected from the TEST programme (2004-2012) for individual countries and regions in eastern and western Europe M. Renteria* (Schaumburg, United States), S. Bouchillon, D. Biedenbach, D. Hoban, M. Hackel, H. Leister-Tebbe Monitoring of ertapenem resistance in Escherichia coli and Klebsiella pneumoniae following introduction of ertapenem into hospital formulary T.Y. Tan* (Singapore, Singapore), L.S.Y. Ng, N. Syahidah P1074 Fluoroquinolone resistance trends among Enterobacteriaceae from European medical centers 2011-2013 D. Biedenbach* (Schaumburg, United States), J. Johnson, S. Bouchillon, M. Hackel, S. Hawser, H. Leister-Tebbe P1076 Distribution of multi-resistant organisms among patients in outpatient renal dialysis units in Germany, 2003-2012 A. Schrauder* (Darmstadt, Germany), C. Wendt P1077 Antibiotic resistance in a collection of Pseudomonas aeruginosa isolated from cystic fibrosis patients through Europe (Belgium, France, Germany and United Kingdom) M.H. Mustafa* (Brussels, Belgium), H. Chalhoub, M. Tunney, S. Elborn, A. Vergison, O. Denis, P. Plésiat, B.C. Kahl, H. Traore, F. Vanderbist, J.M. Buyck, P.M. Tulkens, F. Van Bambeke P1078 Stability of Pseudomonas aeruginosa antimicrobial susceptibility: SMART 2008-2012 R. Badal* (Sacramento, CA, United States), S. Lob, S. Bouchillon, M. Hackel, I. Morrissey, S. Hawser 24th ECCMID / Barcelona Final Programme 193 Chairs, Speakers & Authors P1070 P1071 P1079 Exhibition Tigecycline resistance among clinical isolates in a tertiary care hospital S. Basireddy* (Mahbubnagar, India), V. Kabra, M. Singh, H. Reddy, S. Ali General Information P1069 Posters Monday, 12 May 2014 Poster Sessions Monday, 12 May 2014 P1086 Antimicrobial susceptibility of 29932 pathogens isolated from patients in Canadian hospitals: CANWARD study 2007-2012 G.G. Zhanel, H. Adam, P. Lagacé-Wiens* (Winnipeg, Canada), J. Karlowsky, M. Baxter, K. Nichol, M. Mulvey, G. Golding, D. Hoban 12:30 – 13:30 P1088 Are carbapenemases really pre-requisite for carbapenem-resistance in Enterobacteriaceae? Analysis of isolates submitted to a national reference laboratory in 2012 R. Hill* (London, United Kingdom), D. Meunier, R. Pike, K. Hopkins, K. Patabendige, T. Noorie, N. Woodford Multiclonal spread of OXA-48-producers involving CG258 (ST11) Klebsiella pneumoniae and other Enterobacteriaceae in a VIM and KPC carbapenemase-endemic hospital and emergence in non-hospitalised patients D. Gijon Cordero* (Madrid, Spain), M.I. Morosini, S. García-Fernández, T.M. Coque, P. Ruíz-Garbajosa P1089 OXA-48 carbapenem-producing E. coli isolates from Tchad – another African country M. Naas, S. Bernusset, P. Dabi, N. Fortineau, L. Dortet, P. Nordmann, T. Naas* (Le Kremlin Bicêtre, France) P1090 Influence of bicarbonates on sensitivity of diagnostic tests for OXA-48-producing Enterobacteriaceae V. Studentova, C.C. Papagiannitsis, E. Chudackova, T. Bergerova, J. Hrabak* (Pilsen, Czech Republic) P1091 Great diversity of blaOXA-48-like genes in aquatic systems: have we been neglecting the environment? M. Tacao* (Aveiro, Portugal), C. Maia, I. Silva, A. Correia, I. Henriques P1092 Environmental enterobacteria carrying blaOXA48-like genes M. Tacao* (Aveiro, Portugal), S. Araújo, A. Correia, A. Alves, I. Henriques P1093 Characterisation of OXA-370 producing isolates in Brazil V.B. Ribeiro* (Porto Alegre, Brazil), C.M. Magagnin, F.P. Rozales, M. Pagano, D. Falci, J. Sampaio, A.L. Barth, A.P. Zavascki 194 24th ECCMID / Barcelona Identification of a novel variant of the carbapenemase IMI in Enterobacter spp. B. Aasnaes* (Tromsø, Norway), D. Skaare, B. Haldorsen, A. Sundsfjord, O. Samuelsen P1095 New amino acid modifications in porins of Gram-negative isolates contributing to carbapenem resistance C. Simões, V. Manageiro, D. Jones-Dias, E. Ferreira, M. Marin Canica* (Lisbon, Portugal) P1096 NDM-1, novel TEM-205, novel TEM-213 and other beta-lactamases co-expressed in isolates from cystic fibrosis patients N. Mhlongo, U. Govinden, S. Essack* (Durban, South Africa) P1097 Molecular characterisation of NDM-5 in an Escherichia coli isolate from a non-traveller patient in Spain M. Sole Guiu* (Barcelona, Spain), C. Pitart, A. Román, A. Moreno, I. Roca, J. Vila, F. Marco P1098 Genomic analysis of NDM-1 producing Morganella morganii through whole-genome sequencing A. Olaitan, S.M. Diene, S.K. Gupta, A. Adler, M.V. Assous, J.M. Rolain* (Marseille, France) P1099 Novel tigecycline resistance mechanisms: the alteration of the 30S ribosomal protein S10 in the drug target site in KPC-2-producing Klebsiella pneumoniae clinical isolates C. Feudi, R. Galetti, D. Fortini, L. Villa, A. Carattoli* (Rome, Italy) P1100 Differentiation of K. variicola from K. pneumoniae using PCR-multiplex, and its prevalence among clinical isolates U. Garza-Ramos* (Cuernavaca, Mexico), P. Tinoco, J. Silva-Sanchez, M. Pina-Gonzales, J. Martinez-Barnetche, E. Martinez-Romero, D. Laureano-Gonzalez, P. Garcia-Moguel P1101 Beta-lactamase-producing Gram-negative isolates and molecular mechanisms involved in the expression of tigecycline resistance S. Barbosa, E. Ferreira, V. Manageiro, D. Jones-Dias, Antimicrobial Resistance Surveillance Program in Portugal, M. Marin Canica* (Lisbon, Portugal) P1102 Overexpression of ramA from Citrobacter freundii mediates MDR phenotype in various Citrobacter species and also in Escherichia coli A. Reinhardt* (Hamburg, Germany), F. Kühn, A. Heisig, P. Heisig Poster Area POSTER SESSION IV: Enterobacteriaceae: resistance and fitness P1087 P1094 Final Programme Poster Sessions Impact of a soxR mutation on fitness and antibiotic resistance of an Escherichia coli isolate and identification and characterisation of fitness compensating mutations J. Wenk* (Hamburg, Germany), A. Heisig, P. Heisig P1105 Fitness cost and virulence associated with the development of colistin resistance in Klebsiella pneumoniae S. Christ, L. Sedlaczek, A. Hamprecht, T. Wichelhaus, V.A.J. Kempf, C. Ewers, S. Göttig* (Frankfurt, Germany) P1106 P1107 The discordant relationship between CTX-M-15 mRNA and protein production does not interfere with beta-lactam/beta-lactamase inhibitor combination susceptibilities in Escherichia coli C. Geyer, R. Fowler, N. Hanson* (Nebraska, United States) Multiple drug resistance regions linked to blaCTX-M-15 and atypical class 1 integrons N. Echeverría Chagas* (Montevideo, Uruguay), G. Khalil, A. Ingold, M. Castro, G. Borthagaray, C. Márquez P1108 Analysis of the resistance mechanisms to nitrofurans in Salmonella spp. meat isolates S. Martinez Puchol* (Barcelona, Spain), M.J. Pons, C. Gomes, L. Ruiz, A. Corujo, T.J. Ochoa, J. Ruiz P1109 Common transcriptomic changes in the adaptation of Salmonella enterica Typhimurium to biocides and antibiotics T. Garcao Curiao* (Madrid, Spain), E. Marchi, D. Grandgirard, C. Viti, S. Leib, F. Baquero, M.R. Oggioni, J.L. Martínez, T.M. Coque P1110 OXA-48 and VEB-8 producing Salmonella Kentucky of ST198 in a patient transferred from Libya to Switzerland S.N. Seiffert, V. Perreten, S. Johannes, S. Droz, T. Bodmer, A. Endimiani* (Berne, Switzerland) Shigella sonnei CTX-M-55: first report from South America J. Zurita* (Quito, Ecuador), A.C. Vargas, E. Sierra, I. Alcocer, D. Ortega-Paredes P1112 Characterisation of nalidixic acid-resistant Shigella strains isolated from paediatric patients in Tehran, Iran R. Ranjbar* (Tehran, Iran), V. Behnood, F. Pourali, A. Najafi, N. Sadeghifard, N. Jonaidi, I. Morteza, C. Mammina P1113 Rise in ciprofloxacin-resistant Shigella isolates in Ireland N. De Lappe, J. O Connor, M. Cormican, D. Morris* (Galway, Ireland) P1114 Acquisition of ESBLs in Salmonella spp. and Shigella spp. under systemic cephalosporin therapy B. Spellerberg* (Ulm, Germany), Y. Pfeifer, C. Denzer, C. Posovszky, A. Essig, W. Rabsch P1115 Changes in chlorhexidine sensitivity in Klebsiella pneumoniae as a model Gram-negative pathogen causing healthcare-associated infections L.J. Bock, M.E. Wand* (Salisbury, United Kingdom), J.M. Sutton P1116 Membranotropic effects of 1-adamantane phenol derivative D. Dudikova* (Kiev, Ukraine) P1117 Emergence of 16S rRNA methylase-producing Enterobacteriaceae and P. aeruginosa human clinical isolates and Aeromonas hydrophila isolated from a fish in Serbia B. Gutierrez* (Madrid, Spain), L. Hidalgo, C.M. Ovejero, A. Hoefer, L. Carrilero, A. Santos-Lopez, D. Thomas-Lopez, N. Montero, D. Misic, B. Gonzalez-Zorn P1118 High level fluoroquinolone resistance in Escherichia coli isolated from animals in Turkey is due to multiple mechanisms M. Cengiz* (Bursa, Turkey), P. Sahinturk, L.J.V. Piddock Chairs, Speakers & Authors P1104 P1111 Exhibition Implications for efflux inhibitor design: homologous RND efflux pumps respond to level of AcrB expression J. Blair* (Birmingham, United Kingdom), H.E. Smith, V. Ricci, A.M. Bailey, A.J. Lawler, H. Brown, L.J. Thompson, L.J.V. Piddock 24th ECCMID / Barcelona Final Programme 195 General Information P1103 Posters Monday, 12 May 2014 Poster Sessions Monday, 12 May 2014 12:30 – 13:30 Poster Area POSTER SESSION IV: Pseudomonas sp. and Burkholderia sp.: knowing the mechanics of resistance P1119 Molecular typing and carbapenem resistance in non-clinical Pseudomonas aeruginosa strains Y. Saenz Dominguez* (Logroño, Spain), V. Estepa, C. Casado, B. Rojo-Bezares, C. Torres P1120 Description of KHM-2, a novel metallo-betalactamase, found in a clinical Pseudomonas aeruginosa isolate from Germany N. Pfennigwerth* (Bochum, Germany), A. Hoffmann, C. Belmar Campos, S.G. Gatermann, M. Kaase P1121 Dissemination of GES-1 and GES-5 producing strains of Pseudomonas aeruginosa in France D. Fournier, K. Jeannot, E. Müller, P. Plésiat* (Besançon, France) P1122 Can efflux confer high-level resistance to meropenem (MEM) in Pseudomonas aeruginosa (PA) clinical isolates? H. Chalhoub* (Brussels, Belgium), H. Rodriguez-Villalobos, A. Vergison, O. Denis, B. Kahl, P.M. Tulkens, F. Van Bambeke P1123 Rapid emergence of colistin resistant Pseudomonas aeruginosa mutants A. Nogues, A. Bolard, P. Plésiat, K. Jeannot* (Besançon, France) P1124 Class 3 integron containing metallo-betalactamase in Pseudomonas fulva detected in 3 patients M. Yamamoto* (Kyoto, Japan), Y. Matsumura, M. Nagao, Y. Ito, M. Tanaka, S. Takakura, S. Ichiyama P1125 A subclass B3 metallo-beta-lactamase found in Pseudomonas alcaligenes M. Suzuki* (Tokyo, Japan), M. Matsui, S. Suzuki, Y. Hiraki, F. Kawano, K. Shibayama P1126 Membrane bound beta-lactamase of Burkholderia pseudomallei L.B. Randall, H.P. Schweizer* (Fort Collins, CO, United States) P1127 Molecular characterisation of blaOXA-10-like and dfr23 genes among Burkholderia cepacia complex (BCC) clinical isolates recovered from non-cystic fibrosis patients L.C. Fehlberg* (São Paulo, Brazil), D. Cassu-Corsi, R. Cayô, J.R. Cordeiro-Moura, R. Girardello, A.C. Gales 196 24th ECCMID / Barcelona Final Programme 12:30 – 13:30 Poster Area POSTER SESSION IV: Plasmids and other genetic elements P1128 Natural instability of staphylococcal cassette chromosome mec (SCCmec) in methicillinresistant Staphylococcus aureus strains: a longitudinal study C.R. Scharn* (Omaha, United States), R.V. Goering P1129 Transposons carrying macrolide and/or lincosamide and/or tetracycline resistance genes in Streptococcus agalactiae B. Rojo-Bezares* (Logroño, Spain), J.M. Azcona-Gutiérrez, C. Torres, Y. Sáenz P1131 Characterisation of new genetic elements in Streptococcus mitis F. Santoro* (Siena, Italy), F. Iannelli, G. Pozzi P1132 Uncharted small plasmid carrying blaKPC-2 gene in virulent and multidrug-resistant Pseudomonas aeruginosa from Brazil R. Galetti* (Ribeirao Preto, Brazil), L.N. Andrade, J.C. Ferreira, A. Caratolli, A.L. Darini P1133 Combination of plasmid-encoded qnrA1 and a mutation blocking a central biosynthetic pathway as basis for high-level fluoroquinolone resistance in gyrA single mutants of Escherichia coli H.-P. Sfeir* (Hamburg, Germany), P. Hebel, A. Heisig, P. Heisig P1134 Universal method for detecting and capturing ColE1 plasmids reveals high prevalence of small plasmids in multiresistant clinical Enterobacteriaceae and Pasteurellaceae A. Santos-López* (Madrid, Spain), R. Ortega Huedo, A. San Millan, C. Bernabé, B. Gutierrez, L. Hidalgo, L. Carrilero, C. Martinez-Ovejero, K.N. Prasad, B. Gonzalez-Zorn P1135 New members of the IncL/M resistance plasmid family – comparative genomics of replicons isolated from clinical and environmental samples M. Adamczuk* (Minsk Mazowiecki, Poland), P. Zaleski, L. Dziewit, R. Wolinowska, M. Nieckarz, P. Wawrzyniak, A. Plucienniczak, D. Bartosik P1136 The mRNA half-life of CTX-M-15 transcripts is controlled by a factor encoded on the blaCTX-M15-containing plasmid C. Geyer, N. Hanson* (Nebraska, United States) Poster Sessions P1144 Susceptibility analysis of Gram-negative pathogens collected from ICU and non-ICU patient infections in European countries collected from the TEST programme over ten years (2004-2013) D. Biedenbach* (Schaumburg, United States), S. Bouchillon, M. Hackel, B. Jphnson, I. Morrissey, H. Leister-Tebbe P1138 In vivo transfer of ColE type plasmid encoded OXA-232 in colonised patients J. Yang* (Chungcheongbuk-Do, Korea), J. Park, H. Kim, J. Ryu, Y. Lee, J. Yoo P1145 P1139 New integron encompassing blaVIM-2, qnrVC1 and genes encoding bacterial group II intron from clonal strains of Pseudomonas aeruginosa P.T. Bedlotti, L. Thabet, L. Coulange-Mayonnve, C. Andre, F. M’zali, C. Quentin, V. Dubois* (Bordeaux, France) IMP-5-producing multidrug-resistant Acinetobacter bereziniae: environmental or pathogen? F. Grosso Ledo* (Porto, Portugal), S. Quinteira, C. Sousa, L. Silva, H. Ramos, L. Peixe P1146 First descriptions of plasmid-encoded NDM-1 in carbapenem-resistant Enterobacter cloacae, Escherichia coli and Citrobacter freundii in Brazil J. Campos* (São Paulo, Brazil), M. Silva, E. Barros, M. Pereira, J. Sampaio P1147 Introduction of an accurate screening method to detect carriage of carbapenemase-producing bacteria in patients within 24 hours R.H.T. Nijhuis* (Velp, The Netherlands), N.M. Hanemaaijer, B.J. Slotboom, E.M. Mascini, A.A. Van Zwet P1148 A novel IncN2 plasmid conferring carbapenem resistance by the blaVIM-4 gene identified in Enterobacter cloacae from the Sultanate of Oman D. Fortini* (Rome, Italy), R. Galetti, A. Sonnevend, A. Ghazawi, T. Pal, C. Feudi, A. Al-Jardani, S. Al-Abri, L. Villa, A. Carattoli P1149 Loss of extended-spectrum beta-lactamase resistance genes during storage of bacterial strains C. Verhulst, M. Kluytmans - van den Bergh* (Breda, The Netherlands), I. Willemsen, R. Roosendaal, P. Savelkoul, C. Vandenbroucke-Grauls, C. Verduin, J. Kluytmans P1150 Diverse non-clinical reservoirs of CTX-M-15encoding plasmids and clones in a developing country with close relations with Europe T. Gonçalves Ribeiro* (Porto, Portugal), Â. Novais, L. Peixe, E. Machado Multiresistance plasmid pMOK1 – acquisition of numerous resistance genes by formation of a fusion of broad-host-range replicons M. Adamczuk* (Minsk Mazowiecki, Poland), O. Krysiak, D. Bartosik P1141 The role of HigBA and SplTA toxin-antitoxin systems from Acinetobacter baumannii in plasmid maintenance J. Armalyte* (Vilnius, Lithuania), M. Jurenaite, E. Suziedeliene 12:30 – 13:30 Poster Area POSTER SESSION IV: MDR Gram-negatives – molecular biology of resistance genes P1142 P1143 Dissemination of the cmy-2 cephalosporinase gene in a clinical strain of Klebsiella pneumoniae due to the insertion sequence IS 1294 H. Yassine, L. Bientz, J. Cros, J. Goret, C. Bébéar, C. Quentin, C. Arpin* (Bordeaux, France) Further dissemination of armA methylase gene among nosocomial Enterobacteriaceae isolates at the cancer centre in Bulgaria: emergence of rtmB in Escherichia coli uropathogenic strain S. Sabtcheva* (Sofia, Bulgaria), I.N. Ivanov, E. Dobreva, T. Velinov, I. Petrova, V. Borissova, B. Todorova, K. Ivancheva, T. Kantardjiev 24th ECCMID / Barcelona Final Programme 197 General Information P1140 Chairs, Speakers & Authors Dissemination of plasmids belonging to different incompatibility groups in clinical isolates of E. coli and K. pneumoniae producing extendedspectrum beta-lactamases in Spain B. Ruiz del Castillo* (Santander, Spain), M. Fernandez-Martínez, J. Rodríguez-Baño, A. Pascual, L. Martínez-Martínez Exhibition P1137 Posters Monday, 12 May 2014 Poster Sessions Monday, 12 May 2014 12:30 – 13:30 Poster Area P1158 Wide intrahost-diversity in bacterial genomes, antimicrobial resistance and virulence genes in faecally-carried Escherichia coli identified using whole-genome sequencing N. Stoesser* (Oxford, United Kingdom), C.E. Moore, T. Golubchik, C.M. Parry, N.P. Day, A. Sheppard, A. Giess, T.E. Peto, A.S. Walker, D.W. Crook P1159 Resistance pattern of Escherichia coli and presence of Enterobacteriaceae harbouring extended spectrum beta-lactamase isolated from faecal samples of healthy humans in Styria, Austria H. Galler, G. Zarfel, J. Luxner, V. Breitler, C. Petternel, D. Haas, B. Springer, A.J. Grisold, F.F. Reinthaler* (Graz, Austria), G. Feierl P1160 Classification of non-ESBL E. coli isolates from urinary tract infections (UTI), from general practices F.B. Hertz* (Frederiksberg, Denmark), J.B. Nielsen, P. Littauer, K. Schønning, J.D. Knudsen, A. Løbner-Olesen, N. Frimodt-Møller P1161 Intestinal colonisation with multidrug-resistant Enterobacteriaceae in travellers, immigrants and ‘visiting friends and relatives’: dominance of E. coli-non ST131 producing CTX-M-15 A. Valverde, M.C. Turrientes, E. San Martín, F. Norman, L.M. Moreno, J.A. Pérez-Molina, R. López-Vélez, R. Cantón* (Madrid, Spain) P1162 Emergence of ST224 Escherichia coli harbouring blaCTX-M-15-carrying IncF-type plasmids in swine K. Silva* (São Paulo, Brazil), M. Moreno, N. Lincopan, B. Spira, A.M. Moreno P1163 Prevalence and characteristics of ST131 Escherichia coli isolates: a multicentre study from Korea S. Kim* (Suwon, Korea), Y. Park, J. Yu P1164 Phylogenetic diversity and antibiotic resistance of Escherichia coli from water and faecal pollution sources on an uninhabited island in Portugal M. Alves, A. Pereira, S. Araújo, B. Castro, A. Correia, I. Henriques* (Aveiro, Portugal) P1165 Nitrofurantoin remains active against most uropathogenic E. coli in primary care in Ireland, including ciprofloxacin-resistant 025b-ST131 E. coli – the SIMPle study S. Galvin* (Galway, Ireland), S. Duane, A. Callan, T. White, A.W. Murphy, M. Cormican, A. Vellinga POSTER SESSION IV: Resistance in Enterobacteriaceae P1151 P1152 Strains belonging to clonal group O25b-ST131 are widely disseminated among CTX-M-15 producing Escherichia coli recovered from in- and outpatients in Germany, 2010 B. Körber-Irrgang* (Rheinbach, Germany), Y. Pfeifer, R. Wresch, M. Kresken Prevalence and resistance profile of betalactamases in Escherichia coli isolates from pig holdings in northwestern Germany S. García* (Groningen, The Netherlands), R. Köck, J. Frenzel, A.W. Friedrich, J.W.A. Rossen P1153 Emergence of Escherichia coli sequence type (ST) 131 carrying KPC-3 carbapenemase in Italy M. Accogli, M. Monaco, M. Giufrè, T. Giani, A. García-Fernández, V. Conte, G.M. Rossolini, A. Pantosti, M. Cerquetti* (Rome, Italy) P1154 Detection and molecular characterisation of extended-spectrum beta-lactamase-producing Escherichia coli sequence type ST131 from the Baltic region K. Pai* (Tartu, Estonia), K. Huik, M. Ivanova, S. Kõljalg, A. Pavelkovich, K. Parv, T. Rööp, E. Sepp, P. Naaber, B.S.G. Baltic Antibiotic Resistance collaborative Network P1155 Intraclonal diversity of ST131 Escherichia coli causing bacteraemia in a Spanish hospital over 15 years (1996-2012) I. Rodriguez Fernandez* (Madrid, Spain), C.M. Rodríguez, R. Cantón, E. Loza, J. Zamora, V. Fernández, F. De la Cruz, F. Baquero, T.M. Coque P1156 P1157 Antimicrobial susceptibility profiles of uropathogenic Escherichia coli are associated with specific virulence markers and phylogenetic background V. Tavares Vinhas Calhau* (Coimbra, Portugal), G. Ribeiro, N. Mendonça, G. Da Silva Different recombination frequencies and antibiotic resistance patterns among Escherichia coli phylogenetic groups M.C. Turrientes, J.M. González-Alba, M.I. Morosini, A. Valverde, R. Cantón, F. Baquero, J.C. Galán* (Madrid, Spain) 198 24th ECCMID / Barcelona Final Programme Poster Sessions Monday, 12 May 2014 P1168 Prevalence of broad-spectrum cephalosporin resistance in commensal Escherichia coli strains collected from healthy children in Tunisia S. Ferjani, M. Saidani, Z. Hamzaoui, A. Slim, I. Boutiba* (Tunis, Tunisia) P1169 Characterisation of human uropathogenic ESBLproducing Escherichia coli: spread of CTX-M-27producing B2-025b-ST131 strains in Brno, Czech Republic L. Micenkova* (Brno, Czech Republic), P. Sisková, D. Smajs P1170 First Romanian report on the Escherichia coli ST131 clone C.R. Usein* (Bucharest, Romania), R. Papagheorghe, M. Oprea, M. Condei, M. Straut P1171 Comparison of Escherichia coli ST131 H30 subclone with other ST131 variants and B2-nonST131 isolates A. Novais* (Porto, Portugal), C. Rodrigues, J. Pires, L. Peixe P1172 A multicentre study of the clonal structure and resistance mechanism of KPC-producing E. coli isolates in Israel A. Adler* (Tel Aviv, Israel), T. Miller-Roll, M.V. Assous, Y. Gefen, S. Paikin, D. Schwartz, Y. Wiener-Well, K. Hussein, R. Cohen, Y. Carmeli P1173 P1174 Emergence of E. coli ST405, ST648 and STt101 producing NDM-1 and variants in the Bangladesh environment modulated by specific environmental bacteriophages J. Bugert, A. Nizam, M. Toleman* (Cardiff, United Kingdom) First detection of ESBL and mutations in the regulatory region of ampC gene in Escherichia coli isolated from turtles G. Cortés Cortés* (Puebla, Mexico), G. Moreno, P. Lozano, M.G. Gutiérrez, C. Torres, R.C. Rocha-Gracia 12:30 – 13:30 Poster Area POSTER SESSION IV: Molecular detection of bacterial resistance P1176 Validation of a rapid molecular assay (eazyplex® SuperBug) for frequently occurring carbapenemase genes in Enterobacteriaceae M. Kaase* (Bochum, Germany), A. Kaminski, N. Pfennigwerth, A. Anders, L. Wassill, S.G. Gatermann P1177 Rapid detection of antibiotic resistance genes using recombinase polymerase amplification (RPA) on a microfluidic device R.J. Watson* (Salisbury, United Kingdom), J.M. Sutton, M.N. Tsaloglou, X. Niu, H. Morgan P1178 A rapid two-step algorithm detects and identifies macrolide and beta-lactam antibiotics resistance genes X. Lu* (Shenzhen, China), S.P. Nie, Q. Wang, L.I. Zhang P1179 An Xpert screen to identify carbapenemases producers M. Kazi* (Mumbai, India), V. Menon, C. Nikam, A. Shetty, C. Rodrigues P1180 Detection of carbapenemases by real-time PCR and melt-curve analysis on the BD MAX™ system A. Mischnik* (Heidelberg, Germany), M. Hofko, M. Kaase, S. Zimmermann, A.H. Dalpke P1181 Detection of resistance mechanisms and molecular typing of carbapenem-resistant Acinetobacter baumannii isolated from blood cultures in a Greek tertiary hospital E. Kraniotaki* (Athens, Greece), E. Perivolioti, M. Nepka, V. Papastamopoulos, E. Belesiotou, A. Skoutelis, K. Fountoulis P1182 Screening of rectal swabs for carbapenemresistant microorganisms: evaluation of different screening methods G. Altinkanat Gelmez* (Istanbul, Turkey), A. Karaaslan, S. Ozsoy, M. Kaya, E. Kepenekli, A. Soysal, M. Bakir, G. Soyletir 24th ECCMID / Barcelona Final Programme 199 Posters Prevalence and independent risk factors of phenotypic heterogeneous carbapenem resistance among clinical Escherichia coli isolates causing invasive infections L. Zhang* (Chongqing, China), S. Huang, J. Sun, S. Pu, C. Zhang, L. Zheng Early development of the human gut resistome explored in a birth cohort study C.J.H. Von Wintersdorff* (Maastricht, The Netherlands), J. Penders, P.H.M. Savelkoul, R. Nijsen, E. Hamelmann, S. Lau, K. Gerhold, P.F.G. Wolffs Chairs, Speakers & Authors P1167 P1175 Exhibition Dominance of CTX-M-type extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli originated from community-onset and hospital-onset infection in patients in China S. Xia* (Guangzhou, China), X. Fan, Y. Xu, R.C. Chen, C. Zhuo General Information P1166 Poster Sessions Monday, 12 May 2014 P1183 Evaluation of the AID ESBL line probe assay for rapid detection of extended-spectrum betalactamase (ESBL) and KPC carbapenemase genes in Enterobacteriaceae G.V. Bloemberg, S. Polsfuss, F.P. Maurer* (Zurich, Switzerland), V. Meyer, E.C. Böttger, M. Hombach P1184 Evaluation of a commercial real-time PCR to detect carbapenem-resistant Enterobacteriaceae in rectal swabs E. Carretto* (Reggio Emilia, Italy), D. Barbarini, F. Brovarone, G. Russello, C. Capatti P1185 Development of a real-time PCR (RT-PCR) assay for carbapenemase-producing bacteria, including Enterobacteriaceae B. Mather, P.L. White, M. Wootton* (Cardiff, United Kingdom), R.A. Howe P1186 Carbapenemase-producing multidrug-resistant Klebsiella pneumoniae isolates from blood cultures and prevalence of class 1 integrons E. Kraniotaki* (Athens, Greece), E. Perivolioti, M. Nepka, Z. Psaroudaki, A. Argyropoulou, K. Fountoulis P1187 P1188 P1189 P1190 Molecular characterisation of carbapenemresistant Acinetobacter baumannii and investigation of genetic diversity between local and international clones A. Ulu-Kilic* (Kayseri, Turkey), E. Alp Mese, S. Shaeer Ahmed, G. Dinc Validation of a new DNA extraction method from agar or liquid swabs for molecular detection of MRSA, VRE and KPC utilising the NanoChip® microarray technology Z. Greenberg* (Ashdod, Israel), V. Hurgin, R. Sabban-Amin Next generation sequencing for strain typing and detection of resistance genes: performance of a new commercial method during an outbreak of ESBL-producing ST131 Escherichia coli J. Veenemans* (Tilburg, The Netherlands), I.T. Overdevest, E. Snelders, I. Willemsen, Y. Hendriks, A. Adesokan, G. Doran, A. Rolfe, A. Pettersson, J.A.J.W. Kluytmans VIM-carbapenemases-producing Gram-negatives from river and sea waters in Porto, Portugal P. Cecílio* (Porto, Portugal), D. Gonçalves, H. Ferreira 200 24th ECCMID / Barcelona Final Programme P1191 Characterisation of SCCmec insertion site in 108 isolates lacking the mecA gene and identified as methicillin-resistant Staphylococcus aureus by the rapid PCR GeneXpert test M. Stojanov* (Lausanne, Switzerland), D.S. Blanc P1192 Molecular characterisation of blaNDM-1 in an Acinetobacter pittii strain isolated from Turkey in 2006 N. Mosqueda* (Barcelona, Spain), I. Roca, B. Altun, P. Espinal, M. Akova, J. Vila P1193 Identification of resistance genes in three multiresistant Bacteroides fragilis isolates by whole genome sequencing T. Vognbjerg Sydenham* (Odense, Denmark), H. Hasman, M. Wang, J. Sóki, E. Nagy, U. Stenz Justesen 13:30 – 14:30 Poster Area POSTER SESSION V: Worldwide spread of carbapenem resistance P1194 Molecular epidemiology of carbapenem-resistant Klebsiella pneumoniae and E. coli in Taiwan L. Ma* (Miaoli County, Taiwan), L.K. Siu, J.C. Lin, T.L. Wu, C.P. Fung, J.T. Wang, P.L. Lu, Y.C. Chuang P1195 Carbapenem-resistant Klebsiella pneumoniae clinical isolate harbouring a blaIMP-4- and qnrS-carrying plasmid, as well as a conjugative blaKPC-2 plasmid R.E. Mendes* (North Liberty, United States), S.E. Farrell, W. Wu, Y. Xu, Y. Wang, M. Castanheira, R.N. Jones P1196 First description of NDM-1-producing Klebsiella pneumoniae in Brazil P. Silva Pereira* (Rio de Janeiro, Brazil), M. Borghi, R. Mattos Albano, G. Casemiro Berião, J. Christian Oliveira Lopes, M. Dutra Asensi, A.P. D’Alincourt Carvalho Assef P1197 Dissemination of NDM-1 and OXA-48 in Romania is mainly associated with K. pneumoniae ST101 clone and infrequent carbapenemase-harbouring plasmids (NDM-IncFII and OXA-48-non-typeable) I. Czobor* (Bucharest, Romania), Â. Novais, C. Rodrigues, M.C. Chifiriuc, G. Mihaescu, L. Peixe P1198 Not only OXA-48 but VIM positivity also considered in Klebsiella pneumoniae in Turkey A. Tezer Tekce* (Ankara, Turkey), B. Mert Dinç, O. Unaldi, R.I.Z.A. Durmaz Poster Sessions Emergence in Taiwan of novel imipenem-resistant Acinetobacter baumannii ST455 causing bloodstream infection in critically ill patients L. Hao-Yuan* (Taoyuan, Taiwan), H. Chih-Wei, W.A.N.G. Yi-Hsin, C.H.E.N. Chyi-Liang, C.H.I.U. ChengHsun P1200 Risk factors for carbapenem-resistant Klebsiella pneumoniae colonisation in paediatric units A. Ulu Kilic* (Ankara, Turkey), E. Alp, D. Percin, F. Cevahir, C. Kurkcu, A. Ozturk, A. Ozturk P1209 P1201 A treatment algorithm for carbapenem-resistant Klebsiella pneumoniae infections based on the resistance mechanisms of infecting strains C.J. Clancy* (Pittsburgh, United States), R.K. Shields, L. Chen, B. Kreiswirth, Y. Doi, B. Hao, M.H. Nguyen Microbiological surveillance data of carbapenemase-producing Enterobacteriaceae in Belgium in 2013 T.D. Huang* (Yvoir, Belgium), P. Bogaerts, C. Berhin, B. Jans, O. Denis, Y. Glupczynski P1210 Evidence of coproduction of VIM-1 and NDM-1 beta-lactamase and persistent predominance of metallo-beta-lactamases among Enterobacteriaceae from Croatia B. Bedenic* (Zagreb, Croatia), N. Beader, S. Sardelic, V. Plecko, Z. Bosnjak, D. Varda-Brkic P1211 Spread of an OXA-23-producing trimethoprim/ sulfamethoxazole-susceptible ST2 Acinetobacter baumannii clone in Greek hospitals A. Poulou* (Athens, Greece), V. Pitiriga, M. Nepka, O. Zarkotou, F. Markou, L. Politi, S. Pournaras, A. Tsakris P1212 Carbapenemase-producing Klebsiella pneumoniae from invasive infections, Italy 2011-2013 V. Conte, M. Monaco, T. Giani* (Siena, Italy), F. D’Ancona, M.L. Moro, G.M. Rossolini, A. Pantosti P1213 Characterisation of blaOXA-48 positive members of the Enterobacteriaceae family in Palestine R. Kattan* (Bethlehem, Palestinian Authority), H. Marzouqa, M. Hindiyeh P1214 Community carriage and nosocomial acquisition of blaNDM in hospitals in Karachi: a cohort study M.J. Carvalho* (Cardiff, United Kingdom), A. Mushtaq, S. Aguiar, T. Sequeira, S. Khatoon, N. Chishti, F. Jehan, M. Farooqi, S.U. Kazmi, T.R. Walsh P1215 Association of 16S rRNA methyltransferases and NDM carbapenamase in India C. Martinez Ovejero* (Madrid, Spain), L. Hidalgo, D. Goilo, M. Rahman, B. Gutierrez, L. Carrilero, A. Santos-Lopez, D. Thomas-Lopez, K.N. Prasad, B. Gonzalez-Zorn P1216 Acquisition of strains producing ESBLs or carbapenemases, or resistant to quinolones, during travel to a foreign country; a cohort study E.A. Reuland* (Amsterdam, The Netherlands), G. Sonder, N. Al Naiemi, A. Koek, G.B. Linde, T.J.W. Van der Laar, C.M.J.E. Vandenbroucke-Grauls, A.P. Van Dam P1202 P1203 P1204 P1205 P1206 P1207 Prevalence of carbapenem-resistant Gramnegative bacterial pathogens in European countries, including susceptibility of tigecycline and comparator agents – TEST 2013 S. Bouchillon* (Schaumburg, United States), M. Hackel, R. Badal, S. Hawser, D. Biedenbach, H. Leister-Tebbe Increasing prevalence of carbapenem-resistant Enterobacteriaceae in critically ill patients and use of carbapenems in four intensive care units of Rio de Janeiro, Brazil 2005/2013 J. Delgado Correal* (Rio De Janeiro, Brazil), P. Damasco Vieira, S. Da Cunha, E. De Andrade Marques, A. Proença, M. Amaral, D. Ribeiro, C. Cabral Dias, E.a. Ribeiro Castro Carbapenemase-producing Gram-negative bacilli in Afghanistan D. Delaune* (Saint Mandé, France), H. Elannaz, H. Delacour, M. Collot, S. Bugier, C. Gros, A. Merens Parallel multiregional dissemination of KPCproducing Klebsiella pneumoniae in Poland in 2010-2012 A. BARANIAK* (Warsaw, Poland), R. Izdebski, J. Fiett, K. Bojarska, M. Herda, D. Zabicka, W. Hryniewicz, M. Gniadkowski Epidemiological surveillance of OXA-48-type carbapenemase-producing Enterobacteriaceae in Belgium B. Jans* (Brussels, Belgium), B. Catry First report of pandrug-resistant metallo-betalactamase-producing Pseudomonas aeruginosa isolates in Belarus M. Salavei* (Minsk, Belarus), E. Skleenova, M. Edelstein, O. Krechikova, I. Karpov 24th ECCMID / Barcelona Final Programme 201 Chairs, Speakers & Authors P1208 Exhibition Detection of aminoglycoside-modifying enzymes (AMES) identifies patterns of aminoglycoside resistance among carbapenem-resistant Klebsiella pneumoniae R. Almaghrabi, C.J. Clancy, R.K. Shields, Y. Doi, B. Hao, M.H. Nguyen* (Pittsburgh, United States) General Information P1199 Posters Monday, 12 May 2014 Poster Sessions Monday, 12 May 2014 P1217 P1218 Introduction of highly-resistant bacteria (HRB) to a hospital from patients repatriated or recently hospitalised in a foreign country G. Birgand* (Paris, France), M. Lepainteur, I. Lolom, C. Neulier, F. Reibel, L. Armand-Lefevre, A. Andremont, J. Lucet The characteristics of mecA-positive Staphylococcus aureus from sterile sites with low resistance to oxacillin and cefoxitin and their association with genetic community background (TIST, 2006-2010) W. Wang* (Taichung, Taiwan), S. Tsao, T. Chiueh, J. Lu, P. Hsueh P1227 Molecular epidemiolgy and clinical features of methecillin-susceptible Staphylococcus aureus blood isolates, 2002-2011 P.Y. Chen* (New Taipei City, Taiwan), Y.C. Chuang, J.T. Wang, S.C. Chang P1228 Multi-locus sequence typing of Escherichia coli isolates from a phase 2 complicated intra-abdominal trial for eravacycline C. Fyfe, T. Grossman, P. Tavares, J. Sutcliffe* (Watertown, United States) P1229 Staphylococcal toxic shock syndrome: successful treatment without immunoglobulin therapy in three cases M. Kozma* (Letavertes, Hungary), I. Várkonyi, J. Szabó, Z.R. Dombrádi, K. Rázsó, E. Rakoczi P1230 Epidemiology of carbapenem-resistant bacterial infections in a solid organ transplantation department T. Karampatakis* (Kalamaria-Nea Krini, Greece), A. Geladari, O. Tsiatsiou, E. Iosifidis, C. Antachopoulos, A. Orfanou, A. Karyoti, A. Tsakris, E. Roilides P1231 Targeted gene sequencing for the detection and tracking of VRE in the ICU. What can it tell us? H. McDermott* (Dublin, Ireland), A. Adesokan, H. Humphreys, D. Fitzgerald-Hughes P1232 Reduced responsiveness of blood leukocytes to lipopolysaccharide does not relate to the subsequent development of ICU-acquired infections in critically ill patients L.A. Van Vught* (Amsterdam, The Netherlands), M.A. Wiewel, B.P. Scicluna, H. Belkasim-Bohoudi, M.J. Schutlz, J. Horn, A.J. Hoogendijk, T. Van der Poll P1233 Prevalence of methicillin-resistent Staphylococcus aureus in end stage renal failure patients in Saarland and Hessen A. Dawson* (Saarbrücken, Germany), D. Mischler, C. Petit, B. Gärtner, S. Gräber, R. Klein, U. Heudorf, M. Herrmann Poster Area POSTER SESSION V: Global epidemiology and molecular typing Antibiotic resistance, SCCmec, ability of biofilm formation of methicillin-resistant Staphylococcus aureus isolates in a local hospital in southern China, 2007-2010 Z. Xu* (Guangzhou, China), L. Li, B. Li, G. Yu, M. Shirtliff P1220 Molecular typing of MRSA from Iași, Romania S. Monecke* (Dresden, Germany), E. Müller, O.S. Dorneanu, T. Vremera, R. Ehricht P1221 Genotyping of methicillin-resistant Staphylococcus aureus in the Sultan Qaboos University Hospital, Oman reveals the dominance of PVL-negative ST6-IV/t304 clone E. Udo* (Safat, Kuwait), B. Al-Lawati, B. Mathew, B. Noronha, Z. Al-Muharrmi, S. Thukral P1222 Characterisation of methicillin-resistant Staphylococcus aureus in Kuwait hospitals: 1992-2010 S. Boswihi* (Kuwait City, Kuwait), E. Udo, N. Al-Sweih P1223 Lack of the human host adaptive factor SCN in methicillin-resistant Staphylococcus aureus (MRSA) of human origin A. Larsen* (Copenhagen, Denmark), A. Petersen, J. Larsen, M. Stegger, R. Skov P1224 Molecular characterisation of staphylococcal protein A (spa) deletions in clinical isolates of methicillin-susceptible Staphylococcus aureus C.R. Scharn* (Omaha, United States), F.C. Tenover, R.V. Goering P1225 P1226 Untangling plasmid micro-evolution across an NDM-1-producing Klebsiella pneumoniae outbreak A. Giess* (Oxford, United Kingdom), N. Stoesser, A.E. Sheppard, A. Bashir, R. Sebra, A. Kasarskis, P. Amatya, S. Joshi, S. Thorson, D.W. Crook 13:30 – 14:30 P1219 Staphylococcus aureus, and identification of 3 novel function-impairing mutations N.C. Gordon* (London, United Kingdom), T.E.A. Peto, D. Crook, A.S. Walker, T. Golubchik Prevalence of blaZ in UK clinical isolates of 202 24th ECCMID / Barcelona Final Programme Poster Sessions Monday, 12 May 2014 P1234 Detection and genotyping of human papillomavirus in abnormal cervical samples. Comparison between two different methods R. Salvador * (Madrid, Spain), B. Saavedra, A. Suarez, J.J. Picazo P1235 Susceptibility of clinical methicillin-resistant Staphylococcus aureus isolates to glycopeptides and comparators and their spa types from a Japanese multicentre study, the Kyoto Shiga Microbiology Study Group M. Nagao* (Kyoto, Japan), M. Yamamoto, Y. Matsumura, S. Takakura, S. Ichiyama P1244 Identification of a major worldwide disseminated epidemic genetic lineage among nosocomial Staphylococcus haemolyticus O. Bouchami* (Oeirs, Portugal), H. De Lencastre, M. Miragaia Effect of influenza vaccination on the immune cells in patients with allergy V. Bulgakova* (Moscow, Russia), I. Balabolkin, A. Baranov, I. Smirnov, I. Zubkova, E. Korolkova, I. Larkova, L. Ksenzova, E. Antonova, K. Efendieva P1245 Clinical efficacy of peroral autologous microbial vaccines in the treatment of chronic and recurrent vulvovaginitis M. Czirfuszová* (Bratislava, Slovakia), G. Bertaová, J. Hanzen P1246 Immunomodulative properties of Vibrio cholerae polysaccharide-protein conjugate vaccines J. Korcova* (Bratislava, Slovakia), P. Farka, E. Machova, S. Bystricky P1247 Persistence of yellow fever vaccine-induced antibodies after solid organ transplantation B. Wyplosz* (Le Kremlin Bicêtre, France), C. Burdet, H. François, A. Durrbach, J.C. Duclos-Vallée, M.F. Mamzer-Bruneel, P. Poujol, O. Launay, D. Vittecoq, P.H. Consigny P1248 Prophylaxis with poly(i:c) protects neutropenic mice against Escherichia coli meningoencephalitis S. Ribes* (Göttingen, Germany), C. Arcilla, M. Ott, S. Redlich, S. Schütze, U.K. Hanisch, S. Nessler, R. Nau P1249 IgG2 antibody response to a prime-boost vaccine strategy combining PCV13 followed by PPV23 versus PPV23 alone in HIV-infected adults C. Sadlier* (Dublin, Ireland), N. Conlon, C. Rock, A. Brown, S. O’Dea, J. Dunne, C. Bergin P1250 Seroprevalence of varicella-zoster virus among healthcare workers in Incheon, Korea S.M. Moon* (Incheon, Korea), Y.S. Park, Y.K. Cho P1251 Evaluation of long-term immunity from tetanus and measles in school age children S. Lito* (Geneva, Switzerland), G. Kuli-Lito, E. Kallfa, Z. Ylli, G. Sulcebe P1242 Sequencing, assembly and comparative genomics analysis of six Enterococcus faecium (EFM) ST117, emergent multiresistant clone responsible for an increase of EFM bacteraemia and faecal carriage in Spain R. Tobes* (Granada, Spain), M. Manrique, P. Pareja-Tobes, E. Pareja-Tobes, E. Pareja, A.P. Tedim, P. Ruiz-Garbajosa, R. Canton, F. Baquero, T. Coque Identification of ST8 clonal type as predominant community-associated methicilin-resistant Staphylococcus aureus isolate in Quito, Ecuador applying a multiple locus variable number of tandem-repeat analysis (MLVA) J. Zurita* (Quito, Ecuador), D. Ortega-Paredes, C. González, A.C. Vargas, A. Carrera, E. Sierra, P. Barba POSTER SESSION V: Immunology, vaccination and host defences 24th ECCMID / Barcelona Final Programme 203 Posters P1241 Deciphering evolutionary events and presence of resistance genes by full de novo genome sequencing of clonally related multidrugresistant OXA-48 Klebsiella pneumoniae ST11 isolates R. Tobes* (Granada, Spain), M. Manrique, P. Pareja-Tobes, E. Pareja-Tobes, E. Pareja, D. Gijon, P. Ruiz-Garbajosa, F. Baquero, T. Coque, R. Canton Poster Area Chairs, Speakers & Authors P1240 Evolution of healthcare bacteraemic episodes of Enterococcus faecium (1995-2012) reflects changes in phylogenomic groups with internal clonal epidemic waves A.P. Tedim, P. Ruiz-Garbajosa* (Madrid, Spain), C.M. Rodriguez, L. Derdoy, G. Cardenas, E. Loza, R. Canton, F. Baquero, T.M. Coque 13:30 – 14:30 Exhibition P1239 Community-sequence type ST72 methicillinresistant Staphylococcus aureus (MRSA) isolated from patients in Spain C. Potel* (Vigo, Spain), A. Moreno, S. Otero, S. Rey, J. Rubio, M. Alvarez General Information P1236 P1243 Poster Sessions Monday, 12 May 2014 P1252 Streptococcus pneumoniae antibody titres for the serotypes circulating in Cuba evaluated on clinical trial subjects N. González García* (Havana, Cuba), V. Echemendía, L. Rodriguez, Y. Soroa, A. Garcés, D. García, Y. Valdés, D. Santana, S. Rosell, B. Paredes P1253 Cholera toxin B subunit genetically fused to N-terminal domains of flagellin induces potent humoral immune responses against Pseudomonas aeruginosa in BALB/c mice F. Dakterzada* (lleida, Iran), A. Mohabati Mobarez, M. Habibi Roudkenar P1254 Development of hybrid polypeptides as possible vaccine candidates against Streptococcus agalactiae I.V. Koroleva* (St. Petersburg, Russia), A.S. Lanskova, E.V. Iurlova, T.V. Gupalova, K.B. Grabovskaya, T.A. Kramskaya, A.N. Suvorov P1255 Immunogenicity of conjugate based on detoxified LPS antigen of Vibrio cholerae O139 A. Fleischhackerová* (Bratislava, Slovakia), P. Farkas, S. Bystricks P1256 Transcriptional response of chronic Q fever patients’ mononuclear cells upon C. burnetii stimulation reveals intact interferon-gamma response pathway T. Schoffelen* (Nijmegen, The Netherlands), J. Textoris, A. Ben Amara, C.P. Bleeker-Rovers, M.G. Netea, J.L. Mege, M. Van Deuren P1257 P1258 P1259 P1260 The efficacy of toll-like receptor 4/MD-2 complex agonistic antibody UT12 for chronic lower respiratory tract infection caused by Pseudomonas aeruginosa in mice S. Nakamura* (Nagasaki, Japan), N. Iwanaga, K. Oshima, T. Kajihara, T. Takazono, Y. Imamura, K. Izumikawa, K. Yanagihara, S. Kohno Descriptive study of the cohort of patients diagnosed with BCGitis and analysis of risk factors in a tertiary hospital of northern Spain, from 2003 to 2013 Z.S. Albines Fiestas* (Santander, Spain), A. Arnaiz Garcia, M. Lisa Gracia, J. Fuentes Pastor, J.A. Portillo Martín, F. Campos Juanatey, J.L. Gutierrez Baños, M.C. Fariñas Alvarez Q fever skin test: more than a diagnostic test T. Schoffelen* (Nijmegen, The Netherlands), T. Herremans, T. Sprong, M. Nabuurs-Franssen, J.W.M. Van der Meer, L.A.B. Joosten, M.G. Netea, H.A. Bijlmer, M. Van Deuren The evaluation of cytokine concentration 204 24th ECCMID / Barcelona Final Programme (IL-4,IL-17,IL-23,IL-21) representing cellular and humoral immunity in patients with herpes zoster J.M. Zajkowska* (Bialystok, Poland), A. Moniuszko, A. Zajkowska, A. Garkowski, S. Grygorczuk, R. Swierzbinska, S. Pancewicz P1261 Association of maternal HIV and malaria with reduced placental transfer of antimalarial antibodies L. Moro* (Barcelona, Spain), A. Bardají, C. Dobaño, E. Serra-Casas, B. Sigaúque, P. Cisteró, C.E. Chitnis, P.L. Alonso, C. Menéndez, A. Mayor P1262 Varicella zoster virus-specific cellular immunity in immunocompetent and immunocompromised patients with acute herpes zoster shows distinct alterations of phenotype and functionality D. Schub* (Homburg / Saar, Germany), E. Janssen, T. Vogt, U. Sester, M. Sester, T. Schmidt P1263 The synthetic Streptococcus pneumoniae oligosaccharide conjugate protected mice from severe pneumonia K. Reppe* (Berlin, Germany), C. Anish, R. Bell, C.L. Pereira et al., K. Dietert, L. Sander, A.D. Gruber, N. Suttorp, P.H. Seeberger, M. Witzenrath P1264 Human memory T-cells more avidly respond to Staphylococcus aureus in patients recovering from bloodstream infection A. Brown* (Dublin, Ireland), T.R. Rogers, R. McLoughlin 13:30 – 14:30 Poster Area POSTER SESSION V: Infections in immunocompromised patients P1265 Prospective, cross-sectional analysis of excess mortality associated with documented bacterial and fungal infections in 797 adult patients with haematological malignancies R. Lewis* (Bologna, Italy), M. Stanzani, G. Tolomelli, A. Conficoni, S. Ambretti, P. Viale, M. Cavo, N. Vianelli P1266 Epidemiology of febrile events in acute lymphoblastic leukemia: preliminary results from the “SEIFEM 2012-B” prospective study R. Di Blasi* (Rome, Italy), M. Caira, M. Cesarini, G. Dragonetti, A. Busca, A. Candoni, S. Cesaro, F. Farina, B. Martino, L. Pagano P1267 A nightmare for haematology clinics: extensively drug-resistant (XDR) Acinetobacter baumannii G. Metan* (Kayseri, Turkey), C. Pala, L. Kaynar, F. Cevahir, E. Alp Poster Sessions P1271 P1272 P1273 P1274 P1275 Breakthrough viridans streptococcal bacteraemia in patients with haematological malignancies receiving levofloxacin prophylaxis during the neutropenic phase M. Kimura* (Tokyo, Japan), H. Araoka, A. Yoshida, M. Abe, Y. Okamoto, A. Hishinuma, K. Izutsu, A. Wake, S. Taniguchi, A. Yoneyama Viral respiratory infections in a cohort of adult haematologic patients in a university hospital C. López Sánchez* (Barcelona, Spain), I. Ruiz-Camps, P. Martínez de Salazar, P. Barba, D. Valcárcel, A. Antón, G. Codina, M. Campins, M. Pérez, A. Pahissa Coagulase-negative staphylococci in surveillance cultures and blood cultures from patients with haematological malignancies B. Armannsdottir* (Gothenburg, Sweden), S. Skovbjerg, C. Wennerås Aetiology of bacteraemia as a risk factor for septic shock at the onset of febrile neutropenia in adult cancer patients R.G. Rosa* (Porto Alegre, Brazil), L.Z. Goldani Good outcomes for Gram-negative bacterial necrotising fasciitis in haematology patients R.M. Foo* (Singapore, Singapore), M.L. Tung, M. Poon, N. Smitasin, L.Y. Hsu, P. Tambyah, L.P. Koh, W.J. Chng, L. Chai Descriptive study of pneumococcal bacteraemia in haematology patients: report of 167 cases R. Santiago Alonso* (Terrassa, Spain), I. Ruiz-Camps, M. Rovira, M. Batlle, J.M. Martí-Tutusaus, R. Martino, M. Salavert, J. López, J.M. Moraleda, L. Gómez Risk factors associated with mortality in patients with febrile neutropenia Y. Kartal, N. Erben* (Eskisehir, Turkey), O.M. Akay, S. Nayman Alpat, I. Ozgunes, G. Usluer P1277 Vessel occlusion detected by contrast agent flow interruption in pulmonary computed tomography scan is a characteristic radiomorphological sign in immunocompromised patients with invasive pulmonary aspergillosis M. Reinwald* (Mannheim, Germany), D. Buchheidt, C.A. Weis, S.A. Klein, D. Heidenreich, R. Vogelmann, U. Benck, W.K. Hofmann, T. Henzler, C. Hagelstein P1278 Factors associated with low posaconazole plasma concentrations and impact of structured patient education: a cohort study M. Hoenigl* (Graz, Austria), W. Duettmann, G. Theiler, J. Wagner, J. Prattes, T. Valentin, K. Seeber, F. Prueller, R.B. Raggam, R. Krause P1279 Role of cytomegalovirus DNA measurement in diagnosis and monitoring of active infection in patients receiving immunosuppressive therapy N. Zotos, C. Gartzonika, E. Priavali, C. Boboyianni, S. Levidiotou* (Ioannina, Greece) P1280 CMV infection in patients with haematological malignancies G. Terhes, K. Piukovics, K.P. Sárvári* (Szeged, Hungary), Z. Borbényi, J. Deák P1281 Incidence and clinical outcome of mucormycosis in paediatric cancer patients R. Khedr, Y. Madney* (Cairo, Egypt), H. Hafiz, A. Youssef, H. Taha, H. Al-Mahallawy, O. Hasannain, L. Shalaby P1282 Impact of time to antibiotic on survival in cancer patients with febrile neutropenia: a cohort study R. Rosa* (Porto Alegre, Brazil), L.Z. Goldani P1283 Infections after colorectal cancer surgery and patient survival B. Beovic, M. Kerin Povsic* (Ljubljana, Slovenia) P1284 Infections in hospitalised lung cancer patients D. Kofteridis* (Heraklion, Greece), A. Andrianaki, A. Valachis, K. Spetsotaki, S. Maragou, M. Zacharioudaki, E. Pediaditis, S. Maraki, A. Christidou, G. Samonis P1285 Incidence of Pneumocystis jirovecii pneumonia among groups at risk in HIV-negative patients P. Fillâtre, O. Decaux, M. Revest, S. Jouneau, A. Gacouin, F. Robert-Gangneux, A. Fresnel, C. Guiguen, Y. Le Tulzo, P. Tattevin* (Rennes, France) 24th ECCMID / Barcelona Final Programme 205 Chairs, Speakers & Authors P1270 Epidemiological studies about invasive fungal infection in leukemia patients receiving induction chemotherapy in Taiwan – higher incidences and adverse survival impact were noted B.S. Ko* (Taipei, Taiwan), H.C. Kung, W.C. Li, H.F. Tien, Y.C. Chen P1276 Exhibition P1269 First episode of febrile neutropenia under levofloxacin prophylaxis in recipients of allogeneic haematopoietic stem cell transplants: microbiological characteristics and the role of empiric vancomycin administration M. Kimura* (Tokyo, Japan), H. Araoka, M. Abe, Y. Asano-Mori, N. Uchida, K. Izutsu, S. Taniguchi, A. Yoneyama General Information P1268 Posters Monday, 12 May 2014 Poster Sessions Monday, 12 May 2014 P1286 P1287 P1288 P1289 P1290 P1291 P1292 P1293 Clinical and microbiological features of Campylobacter-related bacteraemia (CRB) at a tertiary care hospital in Madrid (1996-2013) J. Caballero Pérez* (Madrid, Spain), D. López, E. Loza, P. Ruiz-Garbajosa, S. Del Campo, S. García, R. Del Campo, S. Moreno, R. Cantón, A. Moreno The risk of chronic Q fever in rheumatoid arthritis patients with and without anti-TNF-beta therapy T. Schoffelen* (Nijmegen, The Netherlands), L.M. Kampschreur, S.E. Van Roeden, P.C. Wever, A.A. Den Broeder, M.H. Nabuurs-Franssen, P.L.C.M. Van Riel, J.J. Oosterheert, M. Van Deuren, M.C.W. Creemers Risk of bacteraemia in persons on chronic haemodialysis – an observational cohort study L. Skov Dalgaard* (Aarhus, Denmark), M. Nørgaard, B. Jespersen, S. Jensen-Fangel, O. Schmeltz Søgaard Bloodstream infections (BSI) in patients with liver diseases M. Brandolini, M. Corbella, A. De Silvestri, C. Tinelli, G. Albonico, R. Albertini, S. Ludovisi, R. Bruno, P. Marone, E. Seminari* (Pavia, Italy) Asymptomatic bacteriuria in female patients with autoimmune rheumatic diseases: a prospective, observational, case-controlled study S. Georgiadou, M. Gamaletsou, I. Mpanaka, A. Vlachou, V. Syriou, G. Kaltsas, M. Tektonidou, M. Manoussakis, N. Sipsas* (Athens, Greece) Effect of a TNF-alpha antagonist-based therapy on the VZV-specific T-cell immunity in a cohort of psoriatic patients A. Saldan* (Padua, Italy), E. Sandini, D. Tinto, G. Forner, F. Franceschi, S. Piaserico, A. Peserico, G. Palù, D. Abate Cellular immune response to polyomavirus JCV in patients with multiple sclerosis treated with natalizumab A. Di Nauta* (Turin, Italy), F. Sidoti, S. Mantovani, A. Piceghello, M. Rittà, P. Cavalla, S. Masera, C. Costa, R. Cavallo JC virus replication in multiple sclerosis and natalizumab-treated and untreated patients S. Delbue, F. Elia, D. Franciotta, M. Gastaldi, E. Colombo, S. Carluccio, L. Signorini, S. Tadeo, R. Bergamaschi, P. Ferrante* (Milan, Italy) 206 24th ECCMID / Barcelona Final Programme 13:30 – 14:30 Poster Area POSTER SESSION V: Infections in transplant recipients P1294 Epidemiology and risk factors for bloodstream infections in solid organ transplants over a tenyear period B. Berenger* (Edmonton, Canada), K. Doucette, S.W. Smith P1295 Bloodstream infections in allogeneic stem cell transplantation patients: a single-centre, two years experience M. Simon, L. Lebras, G. Lina, M. Michallet, F. Ader, O. Dumitrescu* (Lyon, France) P1296 Infections in patients undergoing liver transplantation for hilar cholangiocarcinoma P. Ramanan* (Rochester, United States), N. Cummins, M.P. Wilhelm, J.K. Heimbach, R. Dierkhising, W. Kremers, C.B. Rosen, G.J. Gores, R.R. Razonable P1297 Treatment of carbapenemase-producing K. pneumoniae in kidney transplant patients M. Freire, F. Spadao, T. Guimaraes, F. Paula, A. Miranda, F. Rossi, H. Caiaffa Filho, E. David-Neto, L. Pierrotti* (São Paulo, Brazil) P1298 Carbapenem-resistant Gram-negative infections in Italian transplant recipients: a nationwide prospective surveillance study S. Lanini* (Rome, Italy), A. Nanni Costa, V. Puro, P. Francesco, P.A. Grossi, F. Vespasiano, A. Ricci, M.G. Ison, Y. Carmeli, G. Ippolito P1299 Risk factors associated with bloodstream infection due to P. aeruginosa harbouring carbapenemases in haematopoietic and stem cell transplant (HSCT) patients L. Chaves* (São Paulo, Brazil), L. Tomich, M. Salomao, J. Ramos, C. Rizek, T. Guimaraes, A. Levin, S. Costa P1300 Clinical and molecular epidemiologic characterisation of methicillin-resistant Staphylococcus aureus (MRSA) infections occurring early after lung transplant C.J. Clancy* (Pittsburgh, United States), M. Shelton, R. Shields, J. Marsh, L. Harrison, C. Bermudez, J. Pilewski, M. Crespo, M.H. Nguyen Poster Sessions Risk factors for recurrent urinary tract infections in kidney transplant recipients M. Bodro Marimont* (Barcelona, Spain), G. Sanclemente, A. Moreno, I. Lipperheide, M. Allali, F. Cofan, N. Esforzado, F. Oppenheimer, J. Bosch, C. Cervera P1303 Clonality and virulence of isolates of VRE in stem cell transplanted patients A.P. Marchi, I.M. Van der Heijden, E.T. Mendes, C.F. Rizek, A. Doi, A.S.S. Levin, S.F. Costa* (Rio de Janeiro, Brazil) P1304 Effect of chlorhexidine bathing on VRE infections in haematopoietic and stem cell transplant (HSCT) patients and impact on emergence of antiseptic resistance E.T. Mendes* (São Paulo, Brazil), A.P. Marchi, I. Van der Heijden, F. Dulley, T.A. De Lima, A.S. Levin, S.F. Costa P1305 P1306 P1307 Incidence of cytomegalovirus drug-resistant mutations in solid organ transplant recipients R. Lopez Aladid* (Barcelona, Spain), M.M. Mosquera, A. Cervilla, F. Sanclemente, F. Cofán, J. Niubó, E. Cordero, P. Muñoz CMV specific humoral immune response kinetics, relationship with cellular immune response and influence in clinical progression of solid organ transplant recipients (R-/D+) P. Blanco Lobo* (Seville, Spain), E. Cordero, E. Cordero, C. Martín-Gandul, M.A. Gentil, J.M. Álamo-Martínez, J. Aznar, A. Porras-González, P. Pérez-Romero Evaluation of specific CMV cellular immunity in kidney transplant patients M. Mauro* (Quattromiglia, Italy), F. Greco, R. Tenuta, F. Leone, R. Bonofiglio, C. Giraldi P1308 Analysis of ganciclovir-resistant CMV (HHV5) using real-time PCR and pyrosequencing technology in clinical samples S. Retzlaff* (Hamburg, Germany), K. Hamprecht P1309 Lack of influence of human cytomegalovirus’ (HCMV) susceptibility to current antiviral drugs on HCMV-encoded US28 chemokine receptor polymorphism S. Burrel, H. Fenaux, L. Kalkias, H. Agut, D. Boutolleau* (Paris, France) Epstein-Barr viral load in whole blood or plasma: what are we measuring? C. Van Leer Buter* (Groningen, The Netherlands), A. Riezebos-Brilman, H.G.M. Niesters P1311 Epidemiology of respiratory viruses (RV) and relationship with chronic lung allograft dysfunction (CLAD) in lung transplant recipients (LTR) J. Gavaldá* (Barcelona, Spain), M. Peghin, H.H. Hirsch, G. Codina, A. Dumoulin, O. Len, J. Solé, J. Rello, A. Roman, A. Pahissa P1312 Characteristics and outcome of 75 HHV-6 reactivations after allogeneic haematopoietic stem cell transplantation A. Quintela, V. Escuret, S. Morisset, L. Gilis, G. Monneret, M. Michallet, F. Ader* (Lyon, France) P1313 Primary HHV-6 infections in paediatric liver and kidney transplant recipients T. Karlsson, R. Loginov, L. Mannonen, T. Jahnukainen, H. Jalanko, I. Lautenschlager* (Helsinki, Finland) P1314 Post-exposure prophylaxis of varicella: VZIG administration within 96 hours vs after 96 hours of exposure to varicella zoster virus S.J. Kim* (Seoul, Korea), Y.H. Kim, S.J. Kim, B.K. Lee, Y.J. Kim P1315 Evaluation of West Nile virus (WNV) in the explanted kidney allograft of a recipient with donor-derived WNV encephalitis H.R. Vikram* (Phoenix, United States), D.M. Blau, J. Bhatnagar, W.-J. Shieh, H.A. Khamash, M.L. Smith, J.E. Staples P1316 Breakthrough candidaemia with Candida parapsilosis during prophylaxis with micafungin after allogeneic haematopoietic stem cell transplantation – cumulative case report C. Langebrake, C. Wolschke, J. Schreiter, H. Rohde* (Hamburg, Germany), N.M. Kröger P1317 Outcome of mucormycosis in haematopoietic stem cell transplant recipients has improved: single centre experience M. Popova, A. Volkova, S. Bondarenko, N. Stancheva, S. Shirayev, Y. Borzova, T. Bogomolova, L. Zubarovskaya, B. Afanasyev, N. Klimko* (St. Petersburg, Russia) 24th ECCMID / Barcelona Final Programme 207 Chairs, Speakers & Authors P1302 P1310 Exhibition ESBL-Enterobacteriaceae-related urinary tract infections in kidney transplant recipients: incidence and risk factors of relapse B. Pilmis, A. Scemla, O. Join-Lambert, O. Lortholary, C. Legendre, J.R. Zahar* (Paris , France) General Information P1301 Posters Monday, 12 May 2014 Poster Sessions Monday, 12 May 2014 P1318 Exserohilum rostratum invasive nasal infection in a renal transplant recipient: the first case report S. Medhajirapath* (Bangkok, Thailand), C. Suankratay, S. Wannalerdsakun, A. Chindamporn P1319 Nocardia infection in the solid organ transplant recipient: a case-control study J. Coussement* (Brussels, Belgium), M.L. Vander Zwalmen, J. Anstey, J. Racapé, S. Roisin, A. Le Moine, M. Antoine, T. Gustot, C. Knoop, F. Jacobs P1320 Is solid-organ transplantation a risk factor for severe malaria? M.C. Nguyen* (Lausanne, Switzerland), P. Gervais, M. Pascual, O. Manuel P1321 Is miltefosine an option as second-line treatment for relapsing visceral leishmaniasis in solid organ transplant recipients? A case series report N. Carrasco Antón, A. Pérez-Jacoiste, F. López Medrano, A. Pérez de Ayala, F. Gamarro, J. Origuen, C. Lumbreras, R. San Juan, M. Lizasoain, J.M. Aguado* (Madrid, Spain) P1322 Poster Area POSTER SESSION V: Diagnostic microbiology: from lower respiratory tract infections to gynaecological infections P1324 P1325 CHROMagar™, StrepB agar and Granada media for detection of group B Streptococcus in vaginal/ rectal prenatal screening E. Grenzner* (l’Hospitalet de Llobregat, Spain), E. Dopico, M. Aguilar, S. Herrero, M.A. Sánchez, R. Manchado P1327 An evaluation of Brilliance™ GBS Agar for the detection of GBS from vaginal swabs C. Hopper, E. Scopes, J. Heckendorn, M. Oleksiuk* (Basingstoke, United Kingdom) P1328 Enhanced detection of group B streptococci from vaginal-rectal swabs by bedside inoculation of the specimen in a Lim broth (Lim®, Copan) S. Mulliez, R. Goemaes, G. Claeys, I. Leroux-Roels, J. Boelens* (Ghent, Belgium) P1329 An audit of compliance with NHS GGC primary care guidelines for the investigation of vaginal discharge in women of reproductive age L. Cottom, G. Lochead, P. Wright* (Glasgow, United Kingdom) P1330 Faecal gas analysis by electronic nose of paediatric IBD patients and healthy controls: a pilot study E.F.J. De Groot* (Amsterdam, The Netherlands), T.G.J. De Meij, Y.E. Lentferink, M.P.C. Van der Schee, T. Paff, C.M.F. Kneepkens, K.H.N. De Boer P1331 Peripheral DNA damage in osteomyelitis S. Tekin Koruk* (Sanliufra, Turkey), S. Selek, S. Sipahioglu, A. Taskin, I. Koruk, A. Kocyigit P1332 Performance of Copan faecal swab and ESwab™ for culturing vancomycin-resistant Enterococcus (VRE) from clinical specimens L. Conter* (Brescia, Italy), B. Massetti, C. Comparini, R. Paroni, S. Castriciano P1333 Fluorescence anisotropy changes induced by aminoglycosides in artificial and natural membranes treated with Pseudomonas aeruginosa C. Istrate* (Bucharest, Romania), T. Savopol, M. Iordache, M. Moisescu, F. Iordache, A. Holban, E. Kovacs P1334 The most appropriate sample type to detect Salmonella in a cohort of Salmonella-positive duck flocks B. Gosling* (Addlestone, United Kingdom), D. Mueller-Doblies, I. Mawhinney, F. Martelli BacT/Alert FAN plus bottles for microbial testing of haematopoietic progenitor cells K. Varettas* (Sydney, Australia) 13:30 – 14:30 P1323 P1326 Evaluation of VITEK® MS identification of Streptococcus pneumoniae and Streptococcus pseudopneumoniae from respiratory samples D. Lazzara* (Porto, Portugal), M. Ribeiro, C. Pina-vaz, S. Conde, M. Espinar The impact of performing bacterial identification (BI) and antimicrobial susceptibility testing (AST) for bronchoalveolar fluid (BAL) cultures 24h a day in a clinical microbiology laboratory H. Pailhoriès* (Angers, France), A. Kouatchet, S. Lasocki, C. Sargentini, C. Lemarié, M. Kempf, C. Mahaza, M.-L. Joly-Guillou, M. Eveillard Prospective study of prevalence and detection methods for Mycoplasma pneumoniae infection among upper respiratory infections in Japan N. Matsuda* (Tokyo, Japan), T. Takahara, M. Tanei, M. Matsuda, A. Nakamura, Y. Uehara, Y. Tabe, T. Naito 208 24th ECCMID / Barcelona Final Programme Poster Sessions Retrospective case-control study of Legionella pneumonia and pneumococcal pneumonia at a university hospital in Japan A. Ueda* (Kanagawa, Japan), M. OKi, A. Tsuda, H. Yanagi, H. Ozawa, A. Takagi Poster Area P1344 Increasing use of 3rd-generation cephalosporins for pneumonia in the emergency department: may some prescriptions be avoided? E. Montassier, N. Lecadet, M. Cousin, N. Goffinet, C. Peron, G. Potel, E. Batard* (Nantes, France) Respiratory system involvement in brucellosis: the results of the Kardelen study H. Erdem, A. Inan* (Istanbul, Turkey), N. Elaldi, L. Gorenek, R. Tekin, S. Gulsun, C. Ataman-Hatipoglu, N. Beeching, O. Deveci, P. Pulmonary brucellosis study group P1345 Corynebacterium pseudodiphtheriticum, a neglected pathogen in lower respiratory tract infections? L. Lozano García* (Murcia, Spain), R. Cesteros Fernández, A.B. Pérez Jiménez, C. Candel Pérez, A. Guarín Montes, R. Blázquez Garrido P1346 Characteristics, serotypes, genotypes and outcome of pneumococcal pneumonia in patients with chronic obstructive pulmonary disease S. Grillo* (L’Hospitalet de Llobregat, Spain), C. Ardanuy, C. Garcia-Vidal, D. Viasus, A. Domenech, A. Simonetti, S. Santos, J. Dorca, J. Liñares, J. Carratalá The scrutiny of detecting community-acquired pneumonia in emergency departments F.P. Paling* (Utrecht, The Netherlands), C.H. Van Werkhoven, S.M. Huijts, M.J.M. Bonten P1347 Comparison of clinical presentations between nursing-home-acquired and community-acquired pneumonia in a Korean teaching hospital: a retrospective cohort study J.H. Lee* (Jeju, Korea), S.J. Koh, S.T. Heo Predicting cardiac complications in patients hospitalised with community-acquired pneumonia: a competing risk analysis D.F. Postma* (Utrecht, The Netherlands), C.H. Van Werkhoven, L.A. Michielsen, K. Verbon, J.J. Oosterheert, M.J.M. Bonten P1348 Procalcitonin as a survival marker in patients with severe CAP K. Bielosludtseva* (Dniepropetrovsk, Ukraine), T. Pertseva, T. Kireeva P1349 Serum phosphorus levels predict adverse outcome in adult patients with communityacquired pneumonia: a cohort study M. Naffaa, M. Mustafa, M. Azzam, T. Machiah, Z.S. Azzam, E. Braun* (Haifa, Israel) 13:30 – 14:30 POSTER SESSION V: Lower respiratory tract infections P1336 P1337 P1338 P1339 P1340 Prevalence of respiratory viruses in patients with upper and lower respiratory tract infection: 2002-2013 C. Cicek* (Izmir, Turkey), A. Arslan, H. Karakus, M. Yalaz, E.U. Saz, H. Pullukcu, G. Cok Clinical and laboratory features of pneumonia in adults with positive pneumococcal urinary antigen test M. Trojanek* (Prague, Czech Republic), K. Herrmannova, O. Dzupova, Z. Blechova, S. Arientova, A. Gabrielova, B. Horova, V. Maresova P1341 Evaluation of causative pathogens of pneumonia that increased as a result of the 2011 tsunami disaster in Japan S. Fujimura* (Sendai, Japan), H. Takahashi, M. Shoji, S. Ubukata, M. Utagawa, T. Kikuchi, Y. Nakano, A. Watanabe P1350 Additional value of the neutrophil/lymphocyte ratio in predicting outcome for hospitalised community-acquired pneumonia: a cohort study D.F. Postma* (Utrecht, The Netherlands), J.C. Schuurman, C.H. Van Werkhoven, J.J. Oosterheert, M.J.M. Bonten P1342 Update on Mycoplasma pneumoniae epidemiology in Jerusalem – a cohort analysis C. Hidalgo -Grass, A. Gayego, A. Abutbul, D. Averbuch, A. Moses, R. Nir-Paz* (Jerusalem, Israel) P1351 Use of meropenem 3g once a day for outpatient treatment of acute infective exacerbations of bronchiectasis S. Sharma* (Kings Lynn, United Kingdom) 24th ECCMID / Barcelona Final Programme 209 Chairs, Speakers & Authors P1343 Exhibition Misidentification of Escherichia albertii strains by ENTEROtest 24 and Biolog GN2 MicroPlate I. Sedlacek* (Brno, Czech Republic), L. Grillova, J. Cernohlavkova, E. Kroupova, P. Svec General Information P1335 Posters Monday, 12 May 2014 Poster Sessions Monday, 12 May 2014 P1352 Bronchiectasis non-cystic fibrosis: clinical and microbiological features G. Barbeito Castiñeiras* (La Coruña, Spain), A. Lama López, A. Palacios Bartolomé, M.L. Pérez del Molino Bernal P1360 Detection of viable but nonculturable Legionella in hospital water network following monochloramine disinfection M. Totaro, B. Casini, F. Aquino* (Pisa, Italy), B. Bruni, A. Porretta, S. Memmini, P. Valentini, G. Privitera P1354 Five-year trend in ventilator-associated pneumonia: a cross-sectional study to evaluate correlation between microbiology and antimicrobial consumption V. Fihman* (Creteil, France), J. Messika, D. Hajage, V. Tournier, S. Gaudry, F. Magdoud, G. Barnaud, C. Branger, D. Dreyfuss, J.D. Ricard P1361 Distribution of clinical Legionella pneumophila isolates in Catalonia (Spain) by monoclonal subgroups and sequence-based typing (SBT) M. Garcia-Nuñez* (Barcelona, Spain), M.L. Pedro-Botet, S. Quero, J.M. Alvarez, I. Barrabeig, M.R. Sala, N. Parraga, J.M. Modol, M. Sabria, O.B.O. Legionella Outbreaks Study Group in Catalonia P1362 Hospital water systems as sources of Legionella – a 7-year follow-up study P. Norton, J. Amaro* (Porto, Portugal), N. Martins, M. Carneiro, M. Ribeiro, J.T. Guimarães P1363 Association between ST1 clone of Legionella pneumophila and hospital exposure: what’s the trigger? P. Cassier* (Lyon, France), C. Campese, Y. Le Strat, D. Che, S. Jarraud P1364 Aspiration as a mode of transmission of Legionnaires’ disease V. Isernia* (Barcelona, Spain), M.L. Pedro-Botet, L. Llobera, L. Mateu, J.M. Mòdol, N. Sopena, M. Sabrià P1365 Colonisation of Legionella species in Turkish baths H. Erdogan* (Antalya, Turkey), H. Arslan P1366 Domestically acquired Legionnaires’ disease: two case reports H. Erdogan* (Antalya, Turkey), H. Arslan 13:30 – 14:30 Poster Area POSTER SESSION V: Legionella: news in clinical and molecular epidemiology P1355 P1356 Specific real-time PCR for detection and identification of Legionella pneumophila serogroup 1 ST47 in clinical and environmental samples P. Cassier* (Lyon, France), C. Ginevra, L. Gomez-Valero, N. Jacotin, C. Buchrieser, S. Jarraud, J. Etienne New high-throughput typing methods for genotyping Legionella pneumophila, Pseudomonas aeruginosa and Staphylococcus aureus strains F. Loisy-Hamon* (La Chapelle Sur Erdre, France), G. Leturnier, B. Lebeau, C. Pourcel, J. Gardes P1357 Microarray-based strain assignment of Legionella pneumophila isolates C. Lück, S. Jarraud, R. Ehricht, N. Jacotin, T. Meyer, M. Petzold, P. Slickers, A. Ziegler, S. Monecke* (Dresden, Germany) P1358 Whole genome sequencing investigation of household water filters and cold water humidifiers as emerging vehicles for paediatric Legionnaires’ disease J. Moran-Gilad* (Beit Kama, Israel), K. Prior, E. Yakunin, T.G. Harrison, L. Valinsky, F. Krux, T. Lazarovitch, M. Mentasti, I. Grotto, D. Harmsen P1359 210 Demonstration of persistence for six years of a single Legionella pneumophila genotype in the freshwater system on a ship experiencing three separate outbreaks of legionellosis C. Ahlen* (Trondheim, Norway), M. Aas, J. Krusnell, O.J. Iversen 24th ECCMID / Barcelona Final Programme 13:30 – 14:30 Poster Area POSTER SESSION V: Molecular diagnostics of respiratory viruses P1367 Point-of-care isothermal nucleic acid amplification is superior to lateral flow immunochromatographic assays for the detection of influenza viruses T.J. Gray* (Westmead, Australia), B. Hazelton, J. Ho, D.E. Dwyer, J. Kok Poster Sessions Monday, 12 May 2014 P1368 Evaluation of the clinical performance of the Xpert® flu next generation assay and BioFire™ FilmArray test for the rapid detection and identification of influenza virus A. Dixon, N. Gleadall, J. Heaney, S. Parmar* (Cambridge, United Kingdom), S. Weller, E. Hutley, M.D. Curran P1369 Evaluation of a new RT-PCR for the detection of influenza A/B and RSV (IMDx flu A/B and RSV for Abbott m2000) S. Gomez* (Madrid, Spain), C. Prieto, C. Vera, L. Folgueira P1378 Comparison PLEX-ID to Prodesse ProFluPlus and Cepheid GeneXpert for the detection of influenza and other respiratory viruses at a tertiary care medical centre in 2012-2013 C.A. Gaydos* (Baltimore, MD, United States), H. Hardick, A. Valsamakis, R. Rothman, A. Dugas Detection of Bordetella pertussis infection by culture, real-time polymerase chain reaction and serologic tests in Valencian community J. Gil-Tomás, J. Colomina-Rodríguez, M. Borrás -Máñez* (Alzira, Spain), V. Pérez-Doñate, S. Górriz-Pintado P1379 Comparison of two multiplex RT-PCR assays for respiratory virus detection: Anyplex RV 16 and Seeplex RV 12 Y. Seo* (Incheon, Korea), P. Park, J. Ahn, K. Kim Pertussis vaccination coverage among adults in Lyon area: a cross-sectional study D. Baratin, C. Del-Signore* (Lyon, France), J. Thierry, E. Caulin, A.C. Jacquard, P. Vanhems P1380 Evaluation of the FilmArray® respiratory panel for the detection of influenza virus A/B and respiratory syncytial virus in respiratory specimens of children T. Bodmer* (Liebefeld, Switzerland), C. Guler, M. Ritzler, W. Baer, M. Risch Antibody levels to pertussis toxin in neonates and prevalence of recent pertussis infection in pregnant women of Catalonia (Spain) P. Plans* (Barcelona, Spain), F. De Ory, M. Campins, E. Alvarez, T. Payà, P. Balfagón, K. Vallvé, P. Godoy, L. Cabero, A. Domínguez P1381 The importance of IgA anti-Bordetella pertussis serologic testing for the diagnosis of acute pertussis O. Dakovic Rode* (Zagreb, Croatia), M.L. Kosanovic Licina, M. Kujundzic Tiljak, J. Iscic Bes, S. Zidovec Lepej, A. Tambic Andrasevic Poster Area P1373 Evaluation of the new RespiFinder® for the detection of respiratory pathogens K. Loens* (Antwerp, Belgium), C. Lammens, H. Goossens, F. Coenjaerts, E. Claas, A. Van Loon, M. Ieven P1382 P1374 Investigation of aetiology by multiplex PCR method in autopsy cases considered for lower respiratory tract infection N. Ziyade* (Istanbul, Turkey), N. Elgormus, G. Yagmur, S. Celik, F. Karayel, Y. Buyuk Surveillance and molecular characterisation of measles in high density populated region of Italy A. Piralla* (Pavia, Italy), M. Premoli, A. Girello, A. Sarasini, F. Baldanti P1383 Characteristics of adult patients who received multiplex respiratory virus polymerase chain reaction (MRV-PCR) tests and risk factors for positive MRV-PCR at a tertiary care centre S. Choi* (Seoul, Korea), M.H. Jeon, J.W. Chung, M.Y. Ahn Insufficient herd immunity against measles in individuals aged <35 years could be one of the factors explaining re-emergence of measles in Catalonia (Spain) P. Plans* (Barcelona, Spain), A. Martínez, G. Carmona, J. Espuñes, N. Torner, M. Jané P1384 Investigation of a rubella outbreak in Chandigarh, north India V. Bansal* (Haryana, India), M. Gupta, J. Khurana, B. Buddhathoki, M. P Singh P1375 P1376 Evaluation of multiple RealStar® RT-PCR kits for the detection of viral respiratory tract infections A. Boesl* (Feldkirch, Austria), K. Baruschke, G. Hartmann, H. Dirschmid, U. Gruber-Mösenbacher, F. Offner 24th ECCMID / Barcelona Final Programme 211 Posters POSTER SESSION V: Bordetella, measles, rubella and mumps Chairs, Speakers & Authors P1372 13:30 – 14:30 Exhibition P1371 Evaluation of throat-swab type and molecular diagnostics for viral aetiologies of acute pharyngitis M. Ali* (Cambridge, United Kingdom), J. Han, C.J. Gunst, S. Lim, K. Luinstra, M. Smieja General Information P1370 P1377 Poster Sessions Monday, 12 May 2014 P1385 Virological and clinical differences between mumps G5 strains S. Gouma* (Bilthoven, The Netherlands), D. Gijselaar, J. Cremer, H. Boot, S. Hahné, M. Koopmans, R. Van Binnendijk 13:30 – 14:30 P1393 Evaluation of the Sofia fluorescent immunoassay for the detection of influenza and respiratory syncytial virus B. Hazelton* (Westmead, Australia), J. Ho, G. Nedeljkovic, D.E. Dwyer, J. Kok P1394 Validation of the Alpha-Tec systems’ ETM™ (enteric transport media) for the detection of rotaviruses and adenoviruses from stool specimens using four rapid immunochromatographic tests J.F. Carod* (Avignon Les St Claude, France), E. Puget, P. Pothier, K. Ambert-Balay P1395 H1N1 testing: rapid detection test vs PCR A. Alhetheel* (Riyadh, Saudi Arabia), A. Albarrag, A. Somily, S. Eifan, Z. Hussain P1396 Evaluation of BIO-FLASH® HSV-1 IgG and HSV-2 IgG assays on Biokit’s BIO-FLASH® analyser M. Cedó, S. Hernanz* (Lliçà d’Amunt, Spain), J. Juliá, B. Ballester, M. Tarragó P1397 The advantages of EIA with improved sensitivity for the detection of low concentrations of HBsAg in samples with markers of HCV, HBV or HIV infections N. Egorova* (Nizhny Novgorod, Russia), S. Igolkina, I. Pyrenkova, I. Sharipova, V. Puzyrev, A. Burkov, T. Ulanova P1398 Evaluation of the new assay Liaison® XL murex HBsAg Quant for the quantification of hepatitis B surface antigen in patients with chronic hepatitis B V. Ghisetti* (Turin, Italy), E. Burdino, T. Ruggiero, A. Olivero, G.P. Caviglia, M. Marietti, A. Smedile P1399 Preliminary assessment of the performance of “Architect® anti-HCV” plus “Liaison® XL murex HCV-AB” to confirm doubtful HCV antibodies’ screening results M. Oggioni, L. Saponaro, S. Giannotta, D. Campisi* (Milan, Italy) P1400 Performance of VIDAS® anti-HCV as a second-line test for the detection of anti-HCV antibodies G. Furlini* (Bologna, Italy), C. Foschi, P. Nardini, S. Galli, M.G. Meliconi, M.P. Landini P1401 Influence of heterogeneity of amino acid sequence varying considerably on immunoreactivity antigen region of HCV NS5 protein from position 2212 to 2313 G. Bochkova* (Nizhniy Novgorod, Russia), T. Ulanova, V. Puzyrev, A. Burkov Poster Area POSTER SESSION V: Molecular and non-molecular diagnostics of viruses P1386 P1387 Evaluation of a rapid test for diagnosis of dengue virus infection in travellers I. Alejo Cancho* (Barcelona, Spain), D. Vilavella, I. Campos, R. Ferre, R. Monte, A. Cañas, D. Martinez, J. Gascon, M.J. Martinez An evaluation of nine rubella IgG assays highlights many discrepancies in the interpretation of the results E. Bouthry, D. Huzly, M.G. Revello, M. Furione, L. Grangeot-Keros, C. Vauloup-Fellous* (Villejuif, France) P1388 Evaluation of new chemiluminescent immunoassays for the determination of HSV-1 IgG and HSV-2 IgG F. De Ory* (Madrid, Spain), M.E. Guisasola, P. Balfagón P1389 Urea-modified protein antigens and their potential to simultaneously induce CMV-specific CD4 and CD8 T-cell responses comparing a new CMV-EliSpot assay and flow-cytometric analysis D. Schub* (Homburg / Saar, Germany), T. Schmidt, C. Guckelmus, S. Kirsch, H. Bendfeldt, L. Deml, U. Sester, M. Sester P1390 P1391 P1392 212 Comparison of three automated immunoassay methods for the determination of Epstein-Barr virus immunoglobulins R. Mouro Pinto* (Porto, Portugal), L. Ribeiro, A. Castro, J.P. Carneiro, M.J. Cardoso Performance of two new fully automated immunoassay panels (Architect and BioPlex™ new EVB IgG) for the determination of serological status of Epstein-Barr virus T.d. Ly* (Ivry Sur Seine, France), C. Coignard, C. Marcenaro Development of human bocavirus antigen test for mariPOC® platform H. Toivola* (Turku, Finland), K. Hedman, V. Peltola, M. Waris, T. Heikkinen, H. Aatola, R. Ruonamo, J.O. Koskinen 24th ECCMID / Barcelona Final Programme Poster Sessions Evaluation of the novel Geenius™ HIV 1/2 HIV confirmatory system A. Blaich* (Basel, Switzerland), A. Geschke, T. Klimkait, K. Rentsch, H. Freidank, A. Buser, R. Frei P1404 Performance evaluation of the Beckman Coulter Veris cytomegalovirus assay on the Veris MDx system Q. Li* (South Bend, United States), J. Williams, K. Maggert, A. Lehr, A. LeMonte, A. Pantone, J. Strefling, S. Kye, D. Broyles, K. Fife Molecular identification of enteroviruses by nested PCR and 5´UTR sequencing N. Piskunova* (Ceske Budejovice, Czech Republic), P. Trubac, O. Scheinost P1412 Validation of human enterovirus (HEV)/ parechovirus (HPEV) multiplex one-step realtime RT-PCR and study of co-infection in positive rotavirus group A (RV-A) children’s stools L. Bubba* (Milan, Italy), E. Pariani, L. Pellegrinelli, A. Ranghiero, V. Primache, A. Amendola, S. Binda P1413 Evaluation of molecular assays for norovirus detection A. Hardie* (Edinburgh, United Kingdom), L. Lin, L. Mackenzie, J. White, J. Kenicer, K. Templeton P1414 Automated molecular detection of viral gastroenteritis with the Roche FLOW System R. Van Rhee-Luderer* (Leeuwarden, The Netherlands), N. Storm, E. Poelstra, A.-J. Stellingwerff, S.J. Mulder, A.H. Brandenburg, J.F.L. Weel, T.A. Schuurs P1405 Cytomegalovirus (CMV) viral load assay for the Veris platform A. Silvestro, H. Duan, S. Lim, J. Richards, J. O’Neil, C. Howell* (Danvers, MA, United States), N. Tusneem, E. Gustafson, T. Scholl P1406 Veris molecular diagnostic system sample-tosample crossover contamination study T. Arnold, M. Rundell* (Chaska, MN, United States), K. Frey, B. Hanson, B. Wilson, H. Qureshi P1415 Molecular detection of enteric viruses: faecal samples versus rectal swabs G. Eltringham* (Newcastle upon Tyne, United Kingdom) P1407 Evaluation of the BK Virus R-gene® quantification kit for determination of BK viral load in renal transplant patients C. Sueur, R. Freitag, E. Soulier, P. Domingo-Calap, S. Caillard, S. Bahram, F. Stoll-Keller, S. Fafi-Kremer* (Strasbourg, France) P1416 Standardised kits for rapid screening of norovirus and enteric viruses in clinical samples F. Loisy-Hamon* (La Chapelle Sur Erdre, France), G. Leturnier, A. Delage, B. Lebeau, K. Balay, P. Pothier P1417 Adaptation of Cepheid’s Smart Norovirus® kit to the automated BD MAX™ open mode platform N. Wohlwend* (Liebefeld-Berne, Switzerland), A. Péclat, M. Ritzler, L. Risch, T. Bodmer P1418 Clinical value of a norovirus (NV) rapid test in patients (PTS) with gastroenteritis (GE) S. Schwartz* (Berlin, Germany), E. Weise, A. Stein, K. Lenz, J. Hofmann, M. Vergoulidou, R. Somasundaram P1419 Development of an external quality assessment panel for the detection of norovirus T. Wijamunige, B. Senechal* (London, United Kingdom), V.L.A. James P1420 Genotyping and double-controlled quantification of parvovirus B19 by multiplex PCR assay M. Nesic* (Belgrade, Serbia), D. Kuzmanovic, I. Joksic, V. Libek, D. Ciric, M. Stanojevic, A. Knezevic, G. Stamenkovic P1408 P1409 P1410 Role of molecular detection of human herpesvirus 7 in central nervous system infections M. Rodriguez Dominguez* (Madrid, Spain), S. Sainz de la Maza, I. Corral, E. Otheo, J.M. González-Alba, R. Cantón, J.C. Galán CSF sample-to-answer validation studies using Focus Diagnostics’ Simplexa™ HSV 1 & 2 direct assay J. Chen* (Cypress, CA, United States), Y. Xie, Y. Parocua, L. Geller, J. Borgeson, N. Wilcox, B. Yu, D. Jaiswal, M. Tabb Performance characteristics of an automated assay on the cobas® 4800 system to detect herpes simplex virus with the cobas® HSV 1 & 2 test D. Fairley* (Pleasanton, Ireland), J. McKenna, C. Cox, P. Coyle 24th ECCMID / Barcelona Final Programme 213 Chairs, Speakers & Authors P1403 P1411 Exhibition Performances of a new rapid confirmatory assay for HIV1/2 serodiagnosis I. Abbate* (Rome, Italy), C. Pergola, M. Pisciotta, R. Sciamanna, C. Sias, N. Orchi, R. Libertone, M.R. Capobianchi General Information P1402 Posters Monday, 12 May 2014 Poster Sessions Monday, 12 May 2014 Transient viraemia in HIV-infected patients: blip, bust or laboratory artifact? D. Bassetti* (Trento, Italy), L. Collini, C. Bezzi, L. Tomasi, C. Nuzzo, P. Lanzafame 13:30 – 14:30 P1422 Quantitative detection of hepatitis B virus (HBV) on the Veris platform J. Arter Williams* (Danvers, MA, United States), J. Rodriguez, Z. Wang, K. Lykstad, G. Donvito, J. Fung, C. Howell, V. Colinayo, E. Gustafson, T. Scholl P1429 Lineage diversification and recombination in human astroviruses M.C. Medici, F. Tummolo, S. De Grazia, G.M. Giammanco, C. Chezzi, F. De Conto, M.C. Arcangeletti, A. Calderaro* (Parma, Italy), V. Martella P1423 Evaluation of performances of versant HCV RNA 1.0 assay (KPCR) and Roche cobas® AmpliPrep/ cobas® TaqMan HCV test v2.0 at low level viraemia L. Mazzuti, M. Lozzi, E. Riva, M. Gentile, O. Turriziani, G. Antonelli* (Rome, Italy) P1430 Norovirus GII.4 Sydney 2012 and new interpandemic recombinant GII.4 strains in Italy M.C. Medici, F. Tummolo, R. Vasile Simone, A. Fazzi, F. De Conto, M.C. Arcangeletti, C. Chezzi, A. Calderaro* (Parma, Italy) P1424 Quantitative detection of hepatitis C virus (HCV) on the Veris platform E. Joseph, R. Gilfillan, Z. Wang, Y. Xu, P. Brannen, J. Wood, C. Howell, E. Gustafson, T. Scholl* (Danvers, MA, United States) P1431 Spatiotemporal transmission and phylodynamics of coxsackievirus B1 P.Y. Chu* (Kaohsiung, Taiwan), Y.Y. Shi, Y.H. Chen P1432 Seven day PCR testing for measles virus – a rapid screening tool to aid public health actions A. Hardie* (Edinburgh, United Kingdom), F. Hamilton, J. White, P. McCulloch, J. Bremner, S. Ramalingam, I. Johannessen, K. Templeton Molecular epidemiology of coxsackievirus A24 variant in Taiwan: VP1 sequence-based analysis of 1985-2010 isolates J.Y. Zeng* (Kaohsiung, Taiwan), C.C. Lin, P.Y. Chu P1433 Comparing detection and quantification of Epstein Barr virus DNA using novel and commercial real-time PCR methods M. Skourtopoulos* (Tornesch, Germany), K. Rutkowski, N. Mueller-Lantzsch, B. Gärtner Sequence and phylogenetic analysis of group A rotavirus strains circulating in Greece; purposes and initial results of ongoing THALES project D. Chatzopoulos* (Karditsa, Greece), L.V. Athanasiou, G. Valiakos, M. Kantere, C. Billinis P1434 Genetic analysis of post-pandemic influenza A(H1N1)PDM09 haemagglutinin virus variants that caused mild, severe and fatal infections in northern Greece A. Melidou, M. Exindari, G. Gioula, N. Malisiovas* (Malisiovas, Greece) P1435 Analysis of mutations associated with severity and antiviral resistance in influenza virus in Catalonia and Valencian community: season 2012-13 M.M. Mosquera* (Madrid, Spain), A. Vilella, N. Torner, M. Miralles, R. Isanta, R. Vendrell, J. Vila, M.A. Marcos, PIDIRAC Sentinel Surveillance Network Physicians of Catalonia, Health Surveillance Network of Valencian Community P1436 Molecular epidemiology of human norovirus strains isolated in south Korea during 2013 H.S. Kim* (Hwaseong, Korea), D.H. Whang, H.S. Kim, J.S. Kim, W. Song P1421 P1425 P1426 P1427 P1428 214 A PCR/ESI-MS assay designed to detect diverse viral agents of disseminated infection in plasma D. Baynes* (Carlsbad, United States), H. Carolan, D. Toleno, D. Metzgar, L. Blyn, R. Sampath POSTER SESSION V: Molecular epidemiology of viruses Performance of LAMP technology versus realtime PCR for BK virus detection in the follow-up of paediatric transplant recipients V. Spuri Vennarucci, L. Gentile* (Rome, Italy), L. Mancinelli, L. Coltella, G. Pizzichemi, M.D. Caione, C. Russo, D. Menichella 24th ECCMID / Barcelona Final Programme Poster Area Poster Sessions Pherotype polymorphism does not explain the population genetic structure of Streptococcus pneumoniae B.A. Evans* (Cambridge, United Kingdom), O.E. Cornejo, D.E. Rozen P1445 Polymorphism of the PcrV protein from Pseudomonas aeruginosa: epidemiological and therapeutic implications C. Bréchet, C. Muller, D. Fournier, P. Plesiat* (Besançon, France) P1446 Prevalence of PI-1 and PI-2 among Streptococcus pneumoniae isolated from healthy nasopharyngeal carriers and children with acute otitis media S. Belanov, I. Tsvetkova, S. Sidorenko* (St. Petersburg, Russia) P1447 Effects of bacterial infection in exacerbations of chronic obstructive pulmonary disease T. Curran* (Belfast, United Kingdom), W.A. Coulter, T.E. McManus, J. Kidney, P.V. Coyle P1448 Streptococcus pneumoniae and Streptococcus pseudopneumoniae: correct identification by a multiplex-PCR based on species specific 16S rRNA BP differences R. Dargis* (Slagelse, Denmark), M. Kemp, J.J. Christensen P1449 Routine real-time PCR for Legionella spp. as part of a front-line syndromic molecular testing algorithm for pneumonia patients in the UK N.J. Gadsby, K.O. Helgason, E.M. Dickson, J.M. Mills, D.S. Lindsay, G.F. Edwards, M.F. Hanson, K.E. Templeton* (Edinburgh, United Kingdom) Poster Area POSTER SESSION V: Molecular diagnosis of respiratory tract bacterial infections P1438 Development and validation of a real-time multiplex PCR method for detection of common atypical respiratory tract bacterial pathogens P. Jayaratne* (Hamilton, Canada) P1439 Application of the BioFire FilmArray® pneumonia panel for rapid identification of the causative agents of ventilator-associated pneumonia M.R. Pulido* (Seville, Spain), P. Moreno-Martínez, F. Fernández-Cuenca, P. Egea, A. Pascual, M.J. McConnell, J.M. Cisneros P1440 Application of molecular biology (FilmArray®) in the early diagnosis of ventilator-associated respiratory infection in critically ill patients M. Gordon Sahuquillo* (Valencia, Spain), A. Quinza Real, E. Villarreal Tello, E.M. Gonzalez Barbera, J.S. Frasquet Artés, I. Calleja Serrano, M.T. Sanchez Aguilar, I. Natividad Furio, J. Bonastre Mora, P. Ramirez Galleymore P1441 Rapid molecular detection and identification of bacteria commonly associated with pneumonia in critically ill patients using a PCR/ESI-MS assay G. Richmond* (Carlsbad, United States), D. Metzgar, M. Frinder, H. Carolan, D. Toleno, L. Blyn, R. Sampath P1442 The development of a multiplex PCR assay for the detection of antibiotic resistance markers in respiratory pathogens A. Penninger* (Maastricht, The Netherlands), Y. Ozog, R. Waber, G. Simons P1443 Comparison of clinical molecular diagnostic tools to discriminate among Burkholderia complex species C.C. Orelio* (Leiden, The Netherlands), M.C. Morsink, S. Beiboer, S. Tektas, H.E. Dekter, W.B. Van Leeuwen Chairs, Speakers & Authors 13:30 – 14:30 P1444 Exhibition Genotype D8 reintroductions of measles in 2013 in Catalonia: replacement of genotype D4? M.M. Mosquera* (Madrid, Spain), N. Torner, M.A. Marcos, M. Jané, R. Isanta, R. Vendrell, J. Vila, J. Costa, And the Measles Control Working Group of Catalonia 24th ECCMID / Barcelona Final Programme 215 General Information P1437 Posters Monday, 12 May 2014 Poster Sessions Monday, 12 May 2014 13:30 – 14:30 Poster Area P1458 Unusual complication by an unusual pathogen: meningitis and bacteraemia due to Neisseria cinerea following a percutaneous rhizotomy of the trigeminal ganglion – a case report M. Von Kietzell* (St. Gallen, Switzerland), K. Huscher, T. Bruderer, D. Goldenberger, S. Emonet, C. Strahm P1459 Retrospective cohort study on the epidemiological patterns of central nervous system herpes simplex virus infection: 10 years of experience of a general hospital M. Casal Moura* (Porto, Portugal), J. Sobrinho Simões, F. Friões, V. Braz, P. Dias, G. Rocha, J. Almeida P1460 A pilot study of the change in temporal lobe volumes in herpes simplex virus (HSV) encephalitis using stereological techniques S. Defres* (Liverpool, United Kingdom), S. Keller, L. Parkes, K. Das, N. Roberts, T. Solomon P1461 Multi-centre validation of an electronic surveillance model for drain-related meningitis M.S.M. Van Mourik* (Utrecht, The Netherlands), K.G.M. Moons, M.J.M. Bonten, On behalf of the drain-related meningitis study group P1462 Time to culture positivity of CSF from ICU patients with external drains E. Kolwijck* (Nijmegen, The Netherlands), A. Hoedemaekers, P. Sturm POSTER SESSION V: Central nervous system infections P1450 Assessment of the management of bacterial meningitis in the adult emergency room C. Delaire* (Poitiers, France), G. Béraud, H. Delelis-Fanien, F. Roblot, J.Y. Lardeur P1451 Acute bacterial meningitis in adults admitted to an infectious diseases department at Lisbon M. Costa Pires* (Lisbon, Portugal), A. Zagalo, J. Neves P1452 Interest of laboratory database analysis for assessing the total number of bacterial meningitis cases managed in a French hospital Y. Vandamme* (Angers, France), P. Holecska, N. Crochette, V. Rabier, P. Abgueguen, M. Kempf, N. Asseray P1453 Group A streptococcal meningitis in adults: a prospective cohort study M.J. Lucas* (Amsterdam, The Netherlands), M.C. Brouwer, D. Van de Beek P1454 Neurological causes of death in adults with Listeria monocytogenes meningoencephalitis: hydrocephalus and seizures I. Pelegrín Senent* (Barcelona, Spain), P.F. Viladrich, J. Ariza, C. Cabellos P1455 Distinctive characteristics of clinical and laboratory presentation between Listeria and pneumococcal meningitis in elderly P. Pagliano* (Naples, Italy), M. Rossi, V. Attanasio, T. Ascione, M. Conte, A. Bernardo, F.S. Faella P1463 Central nervous system (CNS) melioidosis as an emerging mimicker of CNS infection: a first case series in the Philippines A. Masbang* (Quezon City, Philippines), G.M. Zabat, J. Cano, J.H. Gorriceta, C. Dumo, G.S. Mariano P1456 Hyperglycaemia at admission and adjunctival dexamethasone therapy in bacterial meningitis: does it matter? J. Bodilsen* (Aalborg, Denmark), M. Dalager-Pedersen, H.C. Schønheyder, H. Nielsen P1464 Impact of round-the-clock cerebrospinal fluid Gram stain for suspected central nervous system infections on medical therapeutic decisions: does it make a difference? F. Tissot* (Lausanne, Switzerland), G. Prod’hom, G. Greub P1457 Risk factors for mortality in systemic meningococcal disease M. Cabellos Minguez* (Barcelona, Spain), I. Pelegrín, E. Benavent, M.D. Garcia Somoza, F. Gudiol, J. Ariza, P.F. Viladrich P1465 Exploring transmission of Escherichia coli plasmids encoding CMY-2 beta-lactamase between animals and humans in Denmark K.H. Hansen* (Frederiksberg, Denmark), C.A. Nielsen, V. Bortolaia, K. Schønning, Y. Agersø, L. Guardabassi 216 24th ECCMID / Barcelona Final Programme Poster Sessions Tuesday, 13 May 2014 P1467 P1468 P1469 P1470 P1471 P1472 Comparison of culture for MRSA and Staphylococcus aureus with Copan MSwab and ESwab™ specimen collection systems J. Lu, H. Phan, C. Fillmore, C. Honisch* (Pleasanton, United States), M. Lewinski, J. Osiecki Improved detection of difficult-to-detect methicillin-resistant Staphylococcus aureus isolates on ChromID® MRSA SMART agar from surveillance specimens R. Kofol* (Ljubljana, Slovenia), M. Pirs, N. Svent Kucina Evaluation of a new chromogenic medium for isolation of MRSA for use with or without enrichment culture J. Perry* (Newcastle-upon-Tyne, United Kingdom), K. Day, A. Perry, J.M. Roche, S. Orenga P1474 Rapid identification of Staphylococcus epidermidis by colony PCR with S. epidermidis surface protein SesC as a marker L. Khodaparast* (Leuven, Belgium), M. Shahrooei, J. Van Eldere P1475 A novel selective and differential agar medium for Staphylococcus lugdunensis M.H. Leung* (Hong Kong, China), K.H. Chow, P. Law, E.L. Lai, P.L. Ho 12:30 – 13:30 Poster Area POSTER SESSION VI: Epidemiology and clinical impact of S. aureus resistance P1476 Usability and performance of Copan eMRSA broth for the preliminary detection of methicillinresistant Staphylococcus aureus in clinical specimens J. Hirvonen* (Tampere, Finland), S.-S. Kaukoranta Trends in phenotypic and genotypic characteristics of methicillin-resistant Staphylococcus aureus over an eight-year period in a university hospital I. Cirkovic* (Belgrade, Serbia), S. Stepanovic, S. Djukic, J. Trajkovic, A.R. Larsen P1477 Comparison of Copan eMRSA and Oxoid™ contrast MRSA broths for detection of methicillin-resistant Staphylococcus aureus J.J. Hirvonen* (Tampere, Finland), O. Liimatainen, R. Vuento Differences in antibiotic resistance between MRSA genetic linages ST8-SCCmec IV and ST239SCCmec III V. Gostev* (St. Petersburg, Russia), O. Dmitrenko, S. Sidorenko P1478 Resurgence of penicillin-sensitive Staphylococcus aureus in a US tertiary care hospital, a prevalence study M. Chabot* (Springfield, United States), J. Larioza, J. Friderici, M. Stefan, J. Schimmel P1479 Contemporary staphylococcal resistance rates observed in European countries using data derived from TEST programme (2010-2013) B. Johnson* (Schaumburg, United States), M. Hackel, I. Morrissey, D. Biedenbach, S. Bouchillon, J. Johnson P1480 High genetic diversity of S. aureus isolates in cystic fibrosis patients in Austria A.J. Grisold* (Graz, Austria), G. Zarfel, A. Badura, E. Eber, G. Feierl, J. Luxner, U. Wagner-Eibel, S. Johler, L. Masoud- Landgraf Rapid diagnostic testing with GeneXpert improves enrolment in a randomised clinical trial for detection of methicillin-resistant S. aureus in acute bacterial skin and skin structure infections K. Claeys* (Detroit, United States), A. Casapao, J. Pogue, S. Saely, C. Giuliano, W. Hafeez, K. Kaye, D. Levine, S. Davis, M. Rybak Substantial effect of 2% NaCL on minimal inhibitory concentration of communityassociated methicillin-resistant Staphylococcus aureus against oxacillin (TIST study, 2006-2010) W. Wang* (Taichung, Taiwan), T. Chiueh, J. Lu, P. Hsueh 24th ECCMID / Barcelona Final Programme Exhibition P1466 A modified agar screening method for detection of heterogeneous vancomycin-intermediate Staphylococcus aureus L. Cui* (Kanagawa, Japan), H. Matsui, H. Hanaki Posters POSTER SESSION VI: Detection of MRSA and identification of staphylococci at species level P1473 Chairs, Speakers & Authors Poster Area 217 General Information 12:30 – 13:30 Poster Sessions Tuesday, 13 May 2014 P1481 Quantifying the impact of frequent mupirocin usage on the development of low-level mupirocin resistance and the control of healthcareassociated, methicillin-resistant Staphylococcus aureus S.R. Deeny* (London, United Kingdom), C. Worby, J. Edgeworth, B. Cooper, O. Tosas, J.V. Robotham P1482 Beta-lactams versus vancomycin for treatment of methicillin-susceptible Staphylococcus aureus bacteraemia: a retrospective cohort study of data from the U.S. Veterans’ Health Administration J.S. McDanel, E.N. Perencevich, D.J. Diekema, L.A. Herwaldt, T.C. Smith, E.A. Chrischilles, J.D. Dawson, M.L. Schweizer* (Iowa City, IA, United States) P1483 P1484 P1485 P1486 P1487 218 Methicillin-resistant Staphylococcus aureus bacteraemia: elevated MIC and 30-day mortality D. Lye, M.K. Win* (Singapore, Singapore), B.S. Ang, S. Choudhury, P. Krishnan, A. Chow Validation of vancomycin minimum inhibitory concentration and clinical outcomes in methicillin-resistant Staphylococcus aureus isolated from blood culture H. Shoji* (Tokyo, Japan, M. Maeda, K. Fukuchi, T. Shirakura, T. Takuma, K. Tanaka, K. Ishino, Y. Niki) Impact of vancomycin minimum inhibitory concentration on treatment outcome in invasive Staphylococcus aureus infections: Korea INfectious Diseases (KIND) study group K.H. Song* (Seongnam, Korea), K.H. Park, S.I. Jung, N. Yoon, D.M. Kim, H.C. Jang, Y. Park, K.S. Lee, Y.G. Kwak, H.B. Kim Impact of elevated vancomycin minimum inhibitory concentrations on the outcome of catheter-related bloodstream infection due to methicillin-resistant Staphylococcus aureus M. Fernández-Ruiz* (Madrid, Spain), R. San Juan, J.M. Aguado, O. Gasch, M. Camoez, F. López-Medrano, M.A. Domínguez, B. Almirante, B. Padilla, M. Pujol Community staphylococcal pyogenic skin infections in England: PVL, MRSA & clonal diversity A. Kearns* (London, United Kingdom), A. Vickers, B. Pichon, M. Ganner, A. Johnson, A. Charlett, R. Hill 24th ECCMID / Barcelona Final Programme P1488 Molecular epidemiology of methicillin-resistant S. aureus strains from skin and soft tissue infections in Israel A. Rokney* (Jerusalem, Israel), E. Anuka, M. Davidovich-Cohen, O. Barzilay, J. Moran-Gilad, V. Agmon, L. Valinsky P1489 The oral cavity acts as reservoir for Staphylococcus aureus: implications for systemic infections from prosthetic dental appliances L. O’Donnell* (Glasgow, United Kingdom), G. Joyner, K. Smith, D. Robertson, V. Hannah, G. Ramage P1490 Molecular characterisation of methicillinresistant coagulase-negative staphylococci isolated from environment Z. Xu* (London, United Kingdom), H. Mkrtchyan, R.R. Cutler P1491 Distribution of the antiseptic resistance genes qacA/B in 1004 whole genome sequenced methicillin-resistant Staphylococcus aureus isolated in the Danish healthcare setting S. Skovgaard* (Hvidovre, Denmark), P. Worning, H. Westh 12:30 – 13:30 Poster Area POSTER SESSION VI: Epidemiology with molecular typing P1492 Optimising genome assembly and genome finishing of microbial pathogens using whole genome mapping B. Xavier* (Antwerp, Belgium), J. Sabirova, H. Goossens, S. Malhotra-Kumar P1493 Microarray-based genoserotyping and antimicrobial resistance gene determination of Salmonella enterica S. Braun* (Jena, Germany), R. Ehricht P1494 MG7: a scalable fast tool based on cloud computing and graph databases for microbial community profiling M. Manrique, P. Pareja-Tobes, E. Kovach, A. Alekhin, E. Pareja, E. Pareja-Tobes, R. Tobes* (Granada, Spain) P1496 Inter- and intra-cluster mechanisms of Neisseria meningitidis molecular evolution K.V. Siniuk* (Minsk, Belarus), L.P. Titov, K.K. Wollenberg, S. Xirasagar, D. Hurt, Y. Huyen Poster Sessions Isolation of OXA beta-lactamases mRNA and DNA by sequence-specific probes immobilised on magnetic beads C. Brandt* (Jena, Germany), O. Makarewicz, M.W. Pletz P1500 Fast epidemiological typing of the ESKAPE pathogens using ligation-mediated real-time PCR and high resolution melt analysis H. Woksepp* (Kalmar, Sweden), A. Ryberg, H. Billström, L.E. Nilsson, B. Olsson-Liljequist, A. Hällgren, T. Schön P1501 Genotyping of Campylobacter upsaliensis – evidence of transmission from dog to human J. Luxner* (Graz, Austria), G. Zarfel, A.J. Grisold, S. Jelovcan, O. Ableitner, A. Badura, E. Leitner, L. Masoud-Landgraf, G. Feierl P1502 Serotype distribution of S. pneumoniae in children with invasive disease and in healthy nasopharyngeal carriers: usefulness of direct capsular typing by molecular methods E. Del Amo Moran* (Barcelona, Spain), L. Selva, M. F de Sevilla, P. Ciruela, N. Peris, S. Hernandez, L. Salleras, J. J Garcia-Garcia, A. Dominguez, C. Muñoz-Almagro P1503 P1504 A new assay for respiratory tract infections using a lab-on-a-disk platform G. Dingemans* (Maastricht, The Netherlands), R. Waber, F. Schwemmer, M. Keller, W. Kaman, O. Strohmeier, D. De Jongh, G. Simons, W. Van Leeuwen, D. Mark Direct identification of Streptococcus pneumoniae capsular types in pleural fluid by using multiplex PCR combined with automated fluorescence-based capillary electrophoresis L. Selva* (Barcelona, Spain), C. Berger, J.J. Garcia-Garcia, H. De Paz, D. Nadal, C. Munoz-Almagro Comparative analysis of Streptococcus agalactiae isolates causing infections in cattle and humans in Iceland E.S. Björnsdóttir* (Reykjavik, Iceland), E.R. Ferreira Martins, H. Erlendsdóttir, G. Haraldsson, J. Melo-Cristino, M. Ramirez, K.G. Kristinsson P1506 Sequencing-based molecular typing of Treponema pallidum strains in the Czech Republic during years 2012-2013 L. Grillová* (Brno, Czech Republic), H. Petrosová, D. Smajs P1507 DiversiLab® bacterial kit versus species-specific Diversilab® kits for rep-polymerase chain typing of nosocomial pathogens S. Desmet* (Kortrijk, Belgium), A.M. Van den Abeele P1508 Pneumococcal populations assessed by MLST and MLVA K. Elberse* (Bilthoven, The Netherlands), L. Selva, G. Pluister, N. Peris, A. Van der Ende, C. Muñoz-Almagro P1509 Technical evaluation of SpectraCell RA®as a bacterial typing tool for Pseudomonas aeruginosa H. Willemse-Erix* (Rotterdam, The Netherlands), T. Bakker-Schut, G. Puppels, J. Hays, W. Goessens P1510 Strain typing of hospital outbreaks with multi-resistant Gram-negatives using mass spectrometry S. Zimmermann* (Heidelberg, Germany), J. Panitz, I. Burckhardt P1511 Genetic diversity and susceptibility profile of P. aeruginosa isolated from cystic fibrosis patients in São Paulo, Brazil S.T.R. Nora, G.R. Francisco, M.F.C. Bueno, L.V.R.F. Da Silva Filho, D. Garcia* (São Paulo, Brazil) P1512 Phylo-typing of Escherichia coli by use of matrixassisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) M. Sauget, X. Bertrand, D. Hocquet* (Besançon, France) P1513 Multi single-nucleotide polymorphism typing of Escherichia coli with real-time PCR detection: a rapid and reliable tool M. Kristiansson* (Jönköping, Sweden), J. Söderman 24th ECCMID / Barcelona Final Programme 219 Chairs, Speakers & Authors P1499 P1505 Exhibition Interspace microbiome profiling (IS-pro) enables differentiation of IBD subclasses and disease activity by specific loss of bacterial diversity E.F.J. De Groot* (Amsterdam, The Netherlands), T. Grasman, A.A. Van Bodegraven, A.E. Budding, P.H.M. Savelkoul General Information P1498 Posters Tuesday, 13 May 2014 Poster Sessions Tuesday, 13 May 2014 P1514 MLST and PFGE typing of E. coli and K. pneumoniae strains isolated from bloodstream infections from very low birth weight infants in Poland A. Chmielarczyk* (Crakow, Poland), M. Pobiega, D. Romaniszyn, J. Wojkowska-Mach P1515 Development of a multilocus sequence typing scheme for ‘Candidatus Neoehrlichia mikurensis’, a new tick-borne bacterium A. Granqvist* (Gothenburg, Sweden), E. Moore, C. Welinder-Olsson, C. Wennerås P1516 Genetic relatedness of clinical and environmental Acinetobacter baumannii isolates from an outbreak in an intensive care unit: first report from Saudi Arabia using DiversiLab® analysis A. Senok* (Riyadh, Saudi Arabia), G. Garaween, H. Khubnani, A. Raji, A. Shibl 12:30 – 13:30 P1518 P1519 P1520 Genetic diversity among invasive pneumococci: a multicentre study in adult patients in Spain (2010-2013) C. Ardanuy Tisaire* (Barcelona, Spain), E. Cercenado, F. Marco, A. Fleites, M.C. Zúñiga, B. Palop, A. Gil-Brusola, A.I. Aller, A. Fenoll, J. Liñares Serotype distribution and antimicrobial susceptibility of Streptococcus pneumoniae isolated from patients with invasive pneumococcal disease M.A. Vásquez, E. Lain, J. Pereira, M.C. Villuendas, I. Ferrer, A. Rezusta* (Zaragoza, Spain), F.J. Castillo, M.J. Revillo Emerging pneumococcal serotypes and its association with mortality in southern Brazil D.R. Falci* (Porto Alegre, Brazil), M. Garcia, R.M. El Kadri, G.R. Da Cunha, J. Caierão, R. Matusiak, C.A.G. Dias Current snapshot of the Streptococcus pneumoniae PspA clades causing invasive disease in adults A. Tercero* (Barcelona, Spain), M.D. Quesada, D. Fontanals, J. Cámara, A. Fenoll, J. Linares, C. Ardanuy Tisaire 220 24th ECCMID / Barcelona Serotype epidemiology of invasive and colonising Streptococcus pneumoniae, Switzerland, 20102012 L.J. Hathaway, M. Küffer, M. Hilty* (Berne, Switzerland) P1522 Serotype distribution and antimicrobial susceptibility of Streptococcus pneumoniae recovered principally from lower respiratory tract specimens in patients aged >=50 years in select European countries (2009-2011) R.E. Mendes* (Collegeville, PA, United States), A. Costello, R.C. Hollingsworth, R.E. Isturiz, D. Hewlett Jr, D.J. Farrell, R.N. Jones P1523 Increase in serotype 19A and estimated coverage of the pneumococcal conjugate vaccine before and after the approval of the PCV-7 vaccine in northeast Mexico R.M. Hinojosa-Robles* (Monterrey, Mexico), M.J. De la Cruz Valdez, P.A. Hernández-Rodríguez, L. Vera-Cabrera P1524 Two-year surveillance of emm-types and macrolide resistance of paediatric group A streptococcal pharyngitis isolates in the central part of Italy D. Petrelli* (Camerino, Italy), M. Di Luca, G. Gherardi, F. Pimentel de Araujo, P. Bernaschi, A. Repetto, J. Bellesi, M. Prenna, L. Vitali P1525 Epidemiological markers of Streptococcus pyogenes blood strains in Bilbao (Spain) and its relationship with 26 and 30-valent M protein vaccines in development M.J. Sada* (Bilbao, Spain), B. Caceda, M.J. Unzaga, C. Aspichueta, G. Lopez, J.L. Diaz, R. Cisterna P1526 In vitro activity of josamycin against Streptococcus pyogenes isolated from upper respiratory tract infections in France M. Auzou, J. Caillon, C. Poyart, P. Weber, M.C. Ploy, R. Leclercq, V. Cattoir* (Caen, France) P1527 Diversity of resistance and virulence genes among group B streptococcal serotypes in Spain Y. Lopez* (Barcelona, Spain), J. Sala, V. Cepas, E. Sáez López, J. Bosch, J. Vila, S. Soto P1528 Serotype, genotype and antimicrobial resistance of Streptococcus agalactiae isolates from bacteraemic patients in a Korean hospital H.J. Ryu* (Seoul, Korea), Y.J. Park, J.Y. Chang, Y.K. Kim, J.K. Yu Poster Area POSTER SESSION VI: Molecular epidemiology of pneumococcal serotypes and betahaemolytic strepococci P1517 P1521 Final Programme Poster Sessions Tuesday, 13 May 2014 P1538 Improved laboratory reporting times and clinical impact for Panton-Valentine leukocidin testing using the Progenie RealCycler® SAPV real-time PCR assay N. Reading* (Birmingham, United Kingdom), N. Ratnaraja P1539 DNA microarray-based genotyping of 1200 Staphylococcus aureus isolates of the AfricanGerman StaphNet multicentre study U. Ruffing* (Homburg / Saar, Germany), R. Akulenko, L. Wende, S. Schubert, T. Kazimoto, V. Delfino, A. Alabi, M. Herrmann, F. Schaumburg, W. Kern P1540 Clinical relevance and diagnostics of Staphylococcus petrasii, a recently described coagulase-negative species J. Cernohlavkova* (Brno, Czech Republic), P. Petras, P. Svec, R. Pantucek, I. Sedlacek P1541 Characterisation of MRSA isolates non-typeable by the standard spa protocol I. Doel Perez, A. Stoeger, F. Allerberger, W. Ruppitsch* (Vienna, Austria) P1542 Differentiation of Staphylococcus sciuri subspecies P. Svec* (Brno, Czech Republic), P. Petras, R. Pantucek, I. Sedlacek Poster Area POSTER SESSION VI: Molecular diagnosis and epidemiology of staphylococcal infections P1530 Pre-operative screening for Staphylococcus aureus: strategy using PCR on patient admission G. Richalet* (Echirolles, France) P1531 Evaluation of Xpert MRSA SSTI and conventional microbiological procedures for diagnosis of acute osteoarticular infections in patients with implanted orthopaedic devices E. Celeste, B. Brunschweiler, B. Canarelli, M. Biendo* (Maurens Scopont, France), C. Casado P1532 Xpert MRSA: 4 years of experience in a multicentre surveillance protocol; are negatives really negative? M. Depypere* (Aalst, Belgium), P. Vandecandelaere, R. Cartuyvels, G. Coppens, E. Oris, J. Frans, A.M. Van den Abeele, H. De Beenhouwer, K. Van Vaerenbergh P1533 Rapid turn-around time of diagnostic test results for methicillin-resistant Staphylococcus aureus (MRSA) improves quality of patient care and hospital financials H. Probst* (Schwabmünchen, Germany) P1534 Fast screening for MRSA by quadruplex real-time PCR K. Boye* (Hvidovre, Denmark), K. Schønning, H. Westh, G. Lisby P1535 Detection of Staphylococcus aureus and methicillin-resistant S. aureus from nasal specimens of patients from Hvidovre, Denmark and Regensburg, Germany with the cobas® MRSA/SA test A. Line* (Hvidovre, Denmark), O. Engsbro, H. Westh, J. Osiecki, K. Lu, A. Hiergeist, S. Foerster, V. Griefenberg, U. Reischl 12:30 – 13:30 Posters Staphylococcus aureus and Panton-Valentine leukocidin (PVL): an additional threat for a third-level paediatric hospital? P. Cocchi* (Florence, Italy), C. Montagnani, S. Campana, C. Braggion, G. Taccetti, M. De Martino, L. Galli Poster Area POSTER SESSION VI: VRE: epidemiology and control P1543 Report of a VRE outbreak in a neonatal unit at a tertiary teaching hospital in Cape Town, South Africa R. Hoffmann* (Bellville, South Africa), M. Aucamp, C. Moodley, K. Hoek, A. Bekker, A. Dramowski P1544 Use of whole-genome sequencing to investigate the epidemiology of vancomycin-resistant enterococci on an intensive care unit D. Tacke* (Cologne, Germany), M. Gillis, P.G. Higgins, A.D. Millard, J.Z.M. Chan, M.J. Pallen, G. Fätkenheuer, O.A. Cornely, H. Seifert, M.J.G.T. Vehreschild 24th ECCMID / Barcelona Final Programme 221 Chairs, Speakers & Authors 12:30 – 13:30 P1537 Exhibition Epidemiological survey and characterisation of Streptococcus agalactiae isolates from the Semmelweis University Clinics, Budapest, Hungary S. Kardos* (Budapest, Hungary), K. Laub, A. Tóthpál, K. Kristóf, E. Ostorházi, K. Nagy, O. Dobay General Information P1529 Poster Sessions Tuesday, 13 May 2014 P1545 Outbreak of vancomycin-resistant enterococci in a Norwegian hospital: the experience of the Cepheid Xpert® vanA/vanB for VRE screening A. Kanestrom* (Fredrikstad, Norway), A.L. Larsen, J. Ringstad P1546 GeneXpert EV technology allows rapid, noninvasive detection of human enteroviruses in stool and plasma from children with multipleorgan dysfunction syndrome L. Gentile* (Rome, Italy), V. Spuri Vennarucci, M.D. Caione, L. Coltella, G. Pizzichemi, G. Buttinelli, C. Russo, D. Menichella P1547 P1548 P1549 P1550 P1551 P1552 First case of plasmid-mediated linezolidresistance in human faecal isolate of Enterococcus faecium in Norway was associated with import and high-level glycopeptide and aminoglycoside resistance T. Pedersen, T.M. Lunde, L. Thoresen, A. Onken, B. Aasnæs, A. Sundsfjord, K. Hegstad* (Tromsö, Norway) Epidemiology of vancomycin-resistant enterococci from France in 2012 M. Fines-Guyon* (Caen, France), G. Delente, M. Auzou, F. Guérin, V. Cattoir An ST203 vancomycin-resistant Enterococcus faecium outbreak in intensive care units and haematology service: epidemiological and molecular analysis R.K. Arican, O. ONcül, G. Karaahmetoglu, A. ULçay, V. Turhan* (Istanbul, Turkey), A. Acar, H. Erdem, L. Görenek Sequence-type based clinical and epidemiological characteristics of vancomycinresistant enterococci W. Kwang-Sook* (Busan, Korea), C. Jae-Lim, K. Bo-Ram, K. Ji-Eun, K. Kyeong-Hee, K. Jeong-Man, H. Jin-Yeong Vancomycin-resistant Enterococcus faecium colonisation in paediatrics A. Ulu-Kilic* (Kayseri, Turkey), E. Ozhan, D. Altun, D. Percin, T. Günes, E. Alp Mese Nosocomial ST117-E. faecium isolate is more efficient in finger-to-finger transmission than food-borne ST178: intra-individual and gender differences A.M. Sánchez-Díaz* (Madrid, Spain), B. Romero-Hernández, J.D. Caballero, M. Díez-Aguilar, M. Hernández-García, R. Cantón, F. Baquero, R. Del Campo 222 24th ECCMID / Barcelona Final Programme P1553 Epidemiology and control of the first vancomycinresistant Enterococcus outbreak in a tertiarycare hospital in Bangkok, Thailand D. Chotiprasitsakul* (Bangkok, Thailand), P. Santanirand, P. Siriarayapon, P. Thitichai, P. Rotjanapan, S. Sirichot, S. Watcharananun, K. Malathum P1554 Reduction of nosocomial vancomycin-resistant Enterococcus faecium (VRE) colonisation on an intensive care unit after the introduction of antiseptic (octenidine-based) bathing: an interrupted time series analysis S. Messler* (Cologne, Germany), I. Klare, F. Wappler, G. Werner, S.G. Sakka, F. Mattner P1555 Longitudinal whole genome sequencing study of evolution of linezolid resistance during treatment for Enterococcus faecium infections M. David* (Birmingham, United Kingdom), J. Quick, M. Niebel, R. Marudanayagam, B. Oppenheim, N. Loman 12:30 – 13:30 Poster Area POSTER SESSION VI: Mechanism of resistance in Gram-positives: induction and selection P1556 Detection of methicillin-resistant Staphylococcus aureus (MRSA) carrying the mecC gene in wild small mammals in southern Spain P. Gómez* (Logroño, Spain), D. González-Barrio, D. Benito, J.T. García, J. Viñuela, M. Zarazaga, F. Ruiz-Fons, C. Torres P1557 Community-acquired methicillin-resistant Staphylococcus aureus USA300 resists protein A modulation by antibiotics and antimicrobial peptides E. Martin, A. Michel, C. Badiou, M. Bes, F. Laurent, F. Vandenesch, G. Lina, O. Dumitrescu* (Lyon, France) P1558 Linezolid resistance mediated by the cfr gene in staphylococci, first report in France M. Desroches, N. Bourgeois-Nicolaos* (Clamart, France), M. Archambaud, H. Jean-Pierre, F. Jehl, C. Loiez-Durocher, M. Biendo, I. Patry, J.W. Decousser, F. Doucet-Populaire P1559 Impact of active efflux in the development of MDR phenotypes in Staphylococcus aureus S. Santos Costa* (Lisbon, Portugal), M. Viveiros, J. Melo-Cristino, I. Couto Poster Sessions Methicillin resistance in Staphylococcus aureus in Germany 2012 – first regional results I. Noll* (Berlin, Germany), B. Schweickert, M. Feig, T. Eckmanns P1561 Beta-lactam antibiotics can induce vancomycinintermediate resistance in Staphylococcus aureus M. Roch* (Maxilly sur Léman, France), P. Clair, A. Renzoni, M. Bes, A. Martra, A.M. Freydiere, F. Laurent, P. Reix, O. Dumitrescu, F. Vandenesch P1569 Vancomycin MIC creep in MRSA bloodstream isolates in Israel Y. Maor* (Tel Hashomer, Israel), N. Belausov, G. Smollan, G. Rahav, N. Keller P1570 The importance of vancomycin MIC for treatment outcome in MRSA bacteraemia in Slovenia Z. Martincic* (Ljubljana, Slovenia), B. Petek, M. Mueller Premru, B. Beovic P1571 Global transcriptomic analysis by RNA-Seq of Enterococcus faecium in response to ciprofloxacin C. Sinel* (Caen, France), V. Cattoir Evaluation of the prevalence of heterogeneous vancomycin-intermediate Staphylococcus aureus (HVISA) and clinical outcomes in patients with bacteraemia E. Wenzler* (Hilliard, United States), P. Pancholi, D.A. Goff, K.A. Bauer P1572 Binding of avibactam to penicillin-binding proteins (PBPs) of Staphylococcus aureus, Streptococcus pneumoniae and Haemophilus influenzae A. Asli* (Sherbrooke, Canada), E. Brouillette, F. Malouin Molecular epidemiology and susceptibility to new antibiotics among methicillin-resistant Staphylococcus aureus with high vancomycin minimum inhibitory concentration: a multicentre study in Taiwan S.C. Pan* (Taipei, Taiwan), Y.C. Chen, J.T. Wang P1573 Phenotypic and genotypic characterisation of MLS resistance in Propionibacterium acnes isolated from orthopaedic implant infections C. Tournus* (Caen, France), F. Guérin, M. Auzou, V. Cattoir Linezolid susceptibility surveillance in Europe for 2013: ZAAPS program (5,076 strains) R.N. Jones* (North Liberty, IA, United States), J.E. Ross, R.K. Flamm, H.S. Sader, D.J. Farrell, R.E. Mendes P1574 In vivo selection of rifampicin-resistant Listeria monocytogenes during orthopaedic implant infection therapy F.X. Toublet, M. Vergnaud, S. Galopin, M. Auzou, V. Cattoir* (Caen, France) Report of CFR-mediated linezolid resistance in coagulase-negative staphylococci in a university hospital in Ireland T. Wanigasekera* (Wexford, Ireland), S. Fitzgibbon, F. O’Riordan, J. Clair P1575 The first report of CFR-mediated linezolid resistance in Staphylococcus epidermidis in Ireland C. O’Connor* (Limerick, Ireland), N. O’Connell, L. Power, J. Powell, C. Finnegan, A. O’Gorman, C. Dunne, A. Kearns, K.L. Hopkins, R. Hill P1576 Antimicrobial activity of daptomycin and comparator agents tested against methicillinresistant S. aureus and vancomycin-resistant enterococci: analysis of five-year trends in Europe and USA hospitals (2009-2013) H.S. Sader* (North Liberty, IA, United States), D.J. Farrell, R.K. Flamm, R.N. Jones P1562 P1563 P1564 P1565 P1566 In vitro selection of linezolid resistance in coagulase-negative staphylococci isolated from diabetic foot osteitis C. Rouard* (Clamart, France), E. Aslanghul, A. Riviere, M.j. Butel, F. Doucet-Populaire, N. Bourgeois-Nicolaos 12:30 – 13:30 Poster Area POSTER SESSION VI: Resistance surveillance: Gram-positives and others P1567 Comparison of staphylococcal sensitivity data using EUCAST vs CLSI A. Marek* (Glasgow, United Kingdom), D. Henderson, J. Wilson, G. Edwards, T. Inkster 24th ECCMID / Barcelona Final Programme 223 Chairs, Speakers & Authors P1568 Exhibition Potential SNPs relevance to vancomycin-resistant property in clinical isolates of vancomycinintermediate Staphylococcus aureus L. Lin* (Taoyuan, Taiwan), B. Lin, Y. Chou, J. Lu General Information P1560 Posters Tuesday, 13 May 2014 Poster Sessions Tuesday, 13 May 2014 P1577 Tigecycline and daptomycin resistant MRSA among colonisation sites isolates from a period of surveillance when these drugs were not in use in the hospital A.N.G. Dabul, S.C. Bogni, I.L.B.C. Camargo* (Sao Carlos, Brazil) P1578 Emergence of daptomycin nonsusceptibility in Staphylococcus aureus: epidemiological and molecular characterisation of clinical isolates D. García-Martínez de Artola, Á. SampereMartínez, E. Pérez-Roth, J. Alcoba-Flórez* (Santa Cruz de Tenerife, Spain) P1579 Telavancin activity tested against Gram-positive clinical isolates from European hospitals (20112013) using a revised broth microdilution testing method: redefining the baseline activity for telavancin R.E. Mendes* (North Liberty, United States), D.J. Farrell, J.M. Streit, R.N. Jones P1580 Activity of oritavancin tested against Grampositive clinical isolates responsible for documented skin and soft tissue infections in European hospitals (2011-2013) R.E. Mendes* (North Liberty, United States), R.K. Flamm, H.S. Sader, R.N. Jones P1581 High prevalence of mupirocin resistance associated with resistance to other antimicrobials in Staphylococcus aureus isolated from patients in private health care, Western Cape, South Africa E. Wasserman* (Goodwood, South Africa), H. Orth, M. Senekal, J. Harvey P1582 P1583 P1584 Fusidic acid resistance in commensal Staphylococcus aureus in nine European countries: a cross-sectional study C. Den Heijer* (Maastricht, The Netherlands), E. Van Bijnen, J. Paget, E. Stobberingh Prevalence of SCCmec types and solithromycin susceptibility of methicillin-resistant Staphylococcus aureus (MRSA) from respiratory samples collected in 2012-13 I. Morrissey* (Epalinges, Switzerland), P. Fernandes, C. Tacchini, S. Hawser Activity of solithromycin and comparators against streptococci isolated from respiratory samples collected in 2012-2013 I. Morrissey* (Epalinges, Switzerland), P. Fernandes, B. Lemos, S. Hawser 224 24th ECCMID / Barcelona Final Programme P1585 Activity of solithromycin against azithromycinresistant Streptococcus pneumoniae with characterised resistance mechanisms I. Morrissey* (Epalinges, Switzerland), P. Fernandes, B. Lemos, S. Hawser P1586 Prevalence and resistance of commensal Streptococcus pneumoniae in nine European countries R.Y. Yahiaoui* (Maastricht, The Netherlands), C.D.J. Den Heijer, E.M.E. Van Bijnen, W.J. Paget, M. Pringle, H. Goossens, C.A. Bruggeman, F.G. Schellevis, E.E. Stobberingh, And the APRES Study Team P1587 Antibacterial resistance among Streptococcus pneumoniae and Haemophilus influenzae from 11 centres in Vietnam: results from the survey of antibiotic resistance (SOAR) 2009-2011 P.H. Van, P.T. Binh, N.H.L. Minh, I. Morrissey, D. Torumkuney* (Brentford, United Kingdom) P1588 Activity of ceftaroline and comparators against Streptococcus pneumoniae from multiple specimen sources in the European region 2012: assessing worldwide antimicrobial resistance evaluation (AWARE) programme D. Hoban* (Schaumburg, United States), R. Badal, D. Biedenbach, M. Hackel, S. Bouchillon, J. Ambler P1589 Antibacterial resistance among Streptococcus pneumoniae and Haemophilus influenzae from Ukraine. Results from the survey of antibiotic resistance (SOAR) 2011-2013 Y. Feshchenko, A. Dzyublik, T. Pertseva, E. Bratus, Y. Dzyublik, G. Gladka, I. Morrissey, D. Torumkuney* (Brentford, United Kingdom) P1590 History of antibiotic exposure and antibiotic resistance in non-bacteraemic pneumococcal pneumonia A. Shigayeva, W. Rudnick, K. Green, A. Mcgeer* (Toronto, Canada), T. Toronto Invasive Bacterial Diseases Network P1591 Streptococci other than S. pneumoniae – 12-year resistance trends in bacteraemia in the UK and Ireland R. Reynolds* (Bristol, United Kingdom), S. Mushtaq, D.M. Livermore P1592 Haemolytic multidrug-resistant enterococci from diabetic foot ulcers T. Semedo-Lemsaddek, C. Barroco, C. Mottola, J.J. Mendes, J. Melo-Cristino, P. Cavaco-Silva, L. Tavares, M. Oliveira* (Lisbon, Portugal) Poster Sessions Tuesday, 13 May 2014 P1596 In vitro activity of antimicrobial agents tested against anaerobic pathogens from the European TEST programme during 2012-2013 D. Biedenbach* (Schaumburg, United States), M. Hackel, I. Morrissey, S. Bouchillon, H. LeisterTebbe P1597 A 10-year surveillance of the trends of antimicrobial resistance among anaerobes isolated from clinical specimens in Kuwait hospitals W. Jamal* (Safat, Kuwait), M. Shahin, S. Al Najdi, V. Rotimi P1598 Proportions of community-associated and healthcare-associated isolates in the EARSNet data vary depending on pathogen and antimicrobial combination – analysis of EARS-Net data 2011-2012 O.E. Heuer* (Stockholm, Sweden), L. Diaz Högberg, C. Suetens, EARS-Net participants P1599 Svebar – a Swedish early warning and surveillance system for antimicrobial resistance O. Aspevall* (Solna, Sweden), T. Söderblom, L.G. Jacobsson, O. Wilander, G. Kahlmeter, The Svebar AMR surveillance group P1600 Results from the 2013 antimicrobial susceptibility testing external quality assessment (EQA) exercise organised for EARSNet participants A. Laja* (London, United Kingdom), E. Fagan, S. Seaton, A. Couchman, L. Quartermain, A. Thomas, D. Brown, L. Diaz Hogberg, O. Heuer, C. Walton P1602 Lower respiratory tract bacterial infections in cats and dogs: aetiology, antibiotic resistance and current clinical practice J. Fonseca* (London, United Kingdom), T. McHugh P1603 National methicillin-resistant Staphylococcus aureus (MRSA) surveillance in the The Netherlands 1999-2012; changing riskcategories D. Frentz* (Bilthoven, The Netherlands), A. Haenen, L.M. Schouls, T. Bosch, T. Leenstra P1604 Asymptomatic carriage of HA-MRSA in community settings in northern Israel A. Rokney* (Jerusalem, Israel), I. Nissan, L. Valinsky, A. Peretz P1605 The epidemiology and risk factors of Staphylococcus aureus nasal carriage in children attending day-care centres in Hungary K. Laub* (Budapest, Hungary), S. Kardos, A. Tóthpál, K. Nagy, O. Dobay 12:30 – 13:30 Poster Area POSTER SESSION VI: Controling infections in long-term care facilities P1606 Hospital-acquired infections in the elderly in intensive care A. Batirel* (Istanbul, Turkey), N. Benzonana, O. Ak, M. Kavak, D. Akay, Y. Cag, S. Ozer P1607 Urinary tract infections in nursing homes – the need for antibiotic stewardship directed towards the elderly in Denmark C.S. Jensen* (Copenhagen, Denmark) P1608 Effectiveness of a chlorine dioxide-based coating on environmental contamination in care homes for the elderly S. Luk* (Hong Kong, China), T.K. Ng, S.H.H. Leung, I.H.L. Tsang, E.H.Y. Chan, K.W. Choi, K.L. Yeung, J.K.C. Kwan, A.T.Y. Wong P1609 Carriage of extended-spectrum beta-lactamaseproducing Enterobacteriaceae on admission to rehabilitation centres E. Bilavsky* (Petah Tikva, Israel), E. Temkin, Y. Lerman, A. Rabinovich, J. Salomon, C. Lawrence, A. Rossini, A. Salvia, J. Samso, J. Fierro 24th ECCMID / Barcelona Final Programme 225 Posters Isolation of anaerobic bacteria and susceptibility to antimicrobials from burn wounds in plastic surgery and burns unit in a Greek hospital during a two year period M. Orfanidou* E. Vagiakou (Athens, Greece), M. Kamperogianni, L. Drosopoulou, E. Kyriopoulou, G. Ganteris, D. Tsoutsos, Automated surveillance of multidrug-resistant bacteria in the hospital setting J. Elias* (Würzburg, Germany), U. Vogel Chairs, Speakers & Authors P1595 Antimicrobial susceptibility of periodontal pathogens isolated from Slovenian patients M. Furlan* (Ljubljana, Slovenia), P.J. Maver, M. Kocjan Anzic, R. Gazpersic, A.J. Van Winkelhoff, K. Seme P1601 Exhibition P1594 Activity of ceftaroline and comparators against pathogens isolated from skin and soft tissue infections in the European region – AWARE surveillance 2012 R. Badal* (Schaumburg, United States), D. Hoban, M. Hackel, S. Bouchillon, D. Biedenbach, S. Hawser, J. Iaconis General Information P1593 Poster Sessions Tuesday, 13 May 2014 P1610 P1611 P1612 P1613 P1614 P1615 P1616 Nursing homes and long-term care facilities: a reservoir of Escherichia coli producing CTX-M group 1 extended spectrum beta-lactamase, in the north of Portugal D. Gonçalves* (Porto, Portugal), P. Cecílio, H. Ferreira 12:30 – 13:30 Poster Area POSTER SESSION VI: Increasing hand hygiene: new and old perspectives P1617 Compliance with the WHO hand hygiene technique: a prospective observational study S. Tschudin Sutter* (Basel, Switzerland), D. Sepulcri, M. Dangel, H. Schuhmacher, A.F. Widmer P1618 Nursing homes as reservoir of carbapenemresistant Acinetobacter baumannii B. Bedenic* (Zagreb, Croatia), K. Godic-Torkar, N. Beader, N. Barisic, M. Vranic-Ladavac, A. Nikic-Hecer A project to improve hand hygiene compliance A. Pan* (Cremona, Italy), L. Galli, R. Canino, G. Maghini, A. Grandi, A. Grandi, A. Zoncada, S. Lorenzotti, N. Poli, C. Rossi P1619 Influenza in an acute geriatric care ward during the 2012/2013 outbreak: mortality and secondary complications G. Gavazzi* (Grenoble, France), M. Sylvie, Z. Nabil, S. Drevet Low-cost intervention for increasing hand hygiene compliance using RFID in resourceconstrained settings K. Radhakrishna* (Bangalore, India), A. Waghmare, S. Sampath, T. Raj, M. Ekstrand P1621 Extended-spectrum beta-lactamase-producing Enterobacteriacae (ESBLE): significant increase of the prevalence of carriage in elderly residents between 2010 and 2013 D. Roux, H. Cochard, S. Borges Dos Santos, R. Quentin, - Infection Control Study Group, N. Van der Mee-Marquet* (Tours, France) Impact of a hand hygiene campaign involving active patient involvement in a resource-poor country S.F. Mahmood* (Karachi, Pakistan), R. Roshan, S. Dadani, D. Hirani, S. Musani, A. Zafar, M. Salim, E. Hussain P1622 Trends in resistance rates in Enterobacteriaceae collected globally from extended care facilities (TEST 2004-2012) S. Hawser* (Epalinges, Switzerland), R. Badal, D. Biedenbach, I. Morrissey, H. Leister-Tebbe Evaluation of the effectiveness of an infection control programme in paediatric and neonatal intensive care units: a report from a middleincome country E. Alp Mese* (Kayseri, Turkey), T. Orhan, C. Atalay Kurkcu, S. Ersoy, M.L. McLaws P1623 Hand hygiene: from patient’s perspective C. Buke* (Izmir, Turkey), G. Kitapcioglu, G. Guliyeva, U. Onal, H. Akdeniz, E. Aydin, I. Karaca, B. Kilicaslan, E. Koc P1624 Burden of hand soap contamination by Pseudomonas aeruginosa in a tertiary care hospital: a large molecular epidemiological investigation L. Senn* (Lausanne, Switzerland), D.S. Blanc, J. Wasserfallen, P. Genoud, G. Prod’hom, G. Greub, G. Zanetti Implementation of screening for methicillinresistant and methicillin-sensible Staphylococcus aureus and targeted infection control measures in residential homes J. Becker* (Frankfurt, Germany), A. Martin Methicillin-resistant Staphylococcus aureus from residents in one nursing home are more closely related than environmental isolates C. Ludden, G. Brennan, D. Morris, B. Austin, B. O’Connell, M. Cormican* (Galway, Ireland) 226 24th ECCMID / Barcelona Final Programme Poster Sessions Tuesday, 13 May 2014 Risk of occupational HIV, HBV and HCV transmission based on source patient infectiousness and exposure intensity – data from three Swiss hospitals B. Bertisch* (St. Gallen, Switzerland), A. Martin, B. Rusch, P. Vernazza P1626 Genotyping of Pneumocystis in inpatients and hospital healthcare workers support the nosocomial transmission of this infective agent R. Morilla, V. Friaza, M. Martínez-Risquez, M.L. Calero, E. Campano, C. De la Horra, J. Varela, M. Conde, E. Calderón, F. Medrano Gonzalez* (Seville, Spain) P1627 Fatal RSV outbreak in a haematology ward T.O. Jensen, R. Lindeman, J. Gallard, K. Clezy* (Randwick, Australia) P1628 A meta-analysis comparing preemptive and prophylactic strategies to prevent cytomegalovirus disease in renal transplant recipients L. Chen* (Beijing, China), A.P. Ni, J.T. Cui, W.J. Yan, L.J. Kong P1629 P1630 P1631 P1632 Nosocomial Crimean-Congo haemorrhagic fever outbreak in southern Kazakhstan A. Dmitrovskiy* (Almaty, Kazakhstan), M. Shermetova, R. Yegemberdiyeva, L. Yeraliyeva, K. Abdiyeva, Z.H. Shapiyeva, G. Utepbergenova, A. Kuzmina, E. Pak An outbreak of candidaemia due to Candida parapsilosis in an adult intensive care unit Y. Cag, D. Haciseyitoglu, S. Gencer* (Istanbul, Turkey), S. Ozer The features of infectious diseases departments in France and Turkey H. Erdem, J.P. Stahl, A. Inan* (Istanbul, Turkey), M. Akova, C. Rioux, I. Pierre, A. Canestri, E. Haustraete, D. Ozturk-Engin, A. And the study group Carriage of hospital-associated Staphylococcus epidermidis genotypes among staff in an intensive care unit, a single-centre prospective cohort study M. Widerstrom* (Umeå, Sweden), J. Wiström, H. Edebro, T. Monsen POSTER SESSION VI: MDR Enterobacteriaceae from animal sources P1633 Extended-spectrum beta-lactamase, AmpCproducing and fluoroquinolone-resistant Escherichia coli in broilers (poultry) in Italy A. Ghodousi* (Palermo, Italy), C. Bonura, A. Aleo, C. Mammina P1634 Multidrug-resistant Escherichia coli among poultry for human consumption: the relationship between resistance genes and virulence factors N. Mendonca* (Coimbra, Portugal), R. Figueiredo, R. Card, M. Anjum, A. Henriques, R. Sereno, G.J. Da Silva P1635 Prevalence and characterisation of extendedspectrum beta-lactamase-producing Escherichia coli in faecal samples of healthy chickens A. Maamar, S. Hammami, M.S. Abassi, S. Ferjani, N. Dakhli, M. Saidani, A. Slim, I. Boutiba* (Tunis, Tunisia) P1636 Investigation of IncN plasmids encoding CTX-M-1 extended-spectrum beta-lactamase among bovine and swine Escherichia coli isolates collected from diseased animals G.B. Michael* (Neustadt-Mariensee, Germany), K. Kadlec, H. Kaspar, S. Schwarz P1637 Comparative analysis of CTX-M-1 producing E. coli and associated plasmids originating from German livestock farms J. Fischer* (Berlin, Germany), N. Alonso, S. Schmoger, B. Baumann, L. Kreienbrock, B. Appel, A. Kaesbohrer, U. Roesler, R. Helmuth, B. Guerra Roman P1638 Detection of CTX-M-15, SHV-2 and CMY-2 betalactamases in faecal Escherichia coli isolates of dogs in Mexico G. Cortés Cortés* (Puebla, Mexico), F. Bello, P. Lozano, Y. Martínez, C. Torres, R.C. Rocha-Gracia P1639 High prevalence of CTX-M-, CMY-, and OXA-48-like bla genes in food for pets S.N. Seiffert* (Berne, Switzerland), R. Tinguely, A. Lupo, M. Hilty, V. Perreten, A. Endimiani P1640 Cross-sectional prevalence study of CTX-Mtype extended-spectrum beta-lactamases in Escherichia coli strains isolated from healthy poultry B. Castro, R. Abreu, E. Espigares-Rodríguez, A. Madueño* (La Laguna, Spain), E. Moreno-Roldán, M. Espigares, M. Lecuona, A. Arias 24th ECCMID / Barcelona Final Programme 227 Posters P1625 Poster Area Chairs, Speakers & Authors POSTER SESSION VI: Infection control – not only for MDR bacteria 12:30 – 13:30 Exhibition Poster Area General Information 12:30 – 13:30 Poster Sessions Tuesday, 13 May 2014 P1641 Characterisation of extended-spectrum beta-lactamase (ESBL) Escherichia coli isolated between 2011 and 2012 from farm animals in the UK L. Randall* (New Haw, United Kingdom), F. Lemma, R. Card, J. Rogers, C. Teale P1642 Presence of cephalosporin-resistant Salmonella from pig farms using different medication regimes K. Cameron-Veas, M. Sola Guines, L. Fraile, L. Migura* (Barcelona, Spain) P1643 P1644 P1645 P1646 P1647 P1648 Microarray analysis of antimicrobial resistance and virulence genes of Salmonella enterica from food-producing animals: a non-invasive S. infantis associated with uncommon island 1 pathogenicity R. Figueiredo* (Coimbra, Portugal), R. Card, C. Nunes, M. Anjum, N. Mendonça, G. Jorge da Silva Drug sensitivity profiles and genomic rep-PCR fingerprints of Pseudomonas aeruginosa strains from animals against the background of P. aeruginosa’s global population structure D. De Vos* (Schellebelle, Belgium), J. Santos, F. Bilocq, P. Soentjens, S. Jennes, W. Heuninckx, A. Leitao, R. Seixas, M. Oliveira, J. Pirnay Antimicrobial resistance and rep-PCR genomic fingerprinting of Pseudomonas sp. isolated from wild free-living sea turtles in the Gulf of Guinea D. De Vos* (Schellebelle, Belgium), J. Santos, F. Bilocq, P. Soentjens, S. Jennes, W. Heuninckx, A. Leitao, R. Seixas, M. Oliveira, J. Pirnay Trends of antimicrobial drug susceptibility of clinical Stenotrophomonas maltophilia isolates in veterinary medicine A.R. Attili* (Matelica, Macerata, Italy), V. Ngu Ngwa, M. Moriconi, S. Preziuso, A.M. Tambella, V. Cuteri Bias in antimicrobial surveillance data as a result of patient treatment history: an example from the veterinary world P. Damborg* (Frederiksberg, Denmark), L. Boysen, J. Berg, R.F. Larsen, L. Guardabassi Characterisation of ESBL and AmpC cephalosporinase-producing Enterobacteriaceae recovered from diseased European companion animals P. Bogaerts* (Yvoir, Belgium), T.-D. Huang, W. Bouchahrouf, C. Berhin, C. Bauraing, F. El Garch, Y. Glupczynski, Compath Study Group 228 24th ECCMID / Barcelona Final Programme P1650 Decrease of antimicrobial resistance in E. coli from animal husbandry reflects the reduction of antibiotic usage in animals in the The Netherlands K. Veldman* (Lelystad, The Netherlands), C. Dierikx, J. Testerink, M. Japing, A. Van Essen, D. Mevius P1651 Aquaculture as an impact factor for antimicrobial resistance results of the German national antibiotic resistance monitoring (GermVet) H. Kaspar* (Berlin, Germany), K. Heidemanns, U. Steinacker, A. Römer, J. Wallmann 12:30 – 13:30 Poster Area POSTER SESSION VI: Zoonotic antimicrobial resistance P1652 Plasmid diversity among Enterococcus faecalis of different origins, including migratory birds, farm animals and humans R. Leon* (Madrid, Spain), A.P. Tedim, R. Del Campo, C. Novais, A.R. Freitas, L. Peixe, F. Baquero, T.M. Coque P1652a Extended virulence profile of Enterococcus faecium from swine (Europe/USA, 1995-2008) A.R. Freitas, E. Martins, C. Novais* (Sra. da Hora-Matosinhos, Portugal), T.M. Coque, L. Peixe P1653 Molecular characterisation and differences between MRSA ST398 and MSSA ST398 from a pig farmer, his family and the pigs of the farm D. Benito-Pascual* (Logroňo, Spain), C. Aspiroz, E. Gómez-Sanz, P. Gómez, M. González-Dominguez, C. Lozano, M. Zarazaga, C. Torres P1654 Cfr-mediated transferable antibiotic resistance in coagulase-negative staphylococci from nasal colonisation of humans with occupational exposure to livestock C. Cuny* (Wernigerode, Germany), A.T. Feßler, S. Schwarz, W. Witte P1655 Staphylococcus aureus isolated from farm animals and humans in close contact in Greece E. Drougka* (Patras, Greece), A. Foka, A. Liakopoulos, D. Komodromos, D. Sergkelidis, E.D. Anastasiou, E. Peteinaki, I. Spiliopoulou P1656 Dynamic epidemiology of MRSA among horses and staff at a veterinary teaching hospital, and successful intervention to suppress spread M.J. Schwaber* (Tel Aviv, Israel), S. Masarwa, A. Adler, Y. Carmeli, G. Kelmer, A. Steinman Poster Sessions Tuesday, 13 May 2014 P1661 Detection of PVL-positive ST152 and of ST398 MRSA isolates in dairy products in a region of southern Italy M. Monaco* (Rome, Italy), G. La Salandra, F. Mancini, M.G. Basanisi, A. Pantosti Genetic characteristics of 3rd generation cephalosporin-resistant Klebsiella pneumoniae from humans and animals in Switzerland N. Wohlwend, A. Endimiani, V. Perreten* (Berne, Switzerland) P1662 Prevalence and antibiotic susceptibilities of pathogenic Yersinia enterocolitica strains in pigs slaughtered in northern Italy M.C. Ossiprandi* (Parma, Italy), L. Zerbini P1663 Temporal and spatial dissemination of two main genotypes of Streptococcus dysgalactiae subsp. equisimilis isolates in Brazil and evidence for zoonotic transmission L.G. Silva, G.L. Genteluci, T.S. Glatthardt, M.C. De Mattos, A.M.S. Figueiredo, B.T.F. Carvalho* (Rio de Janeiro, Brazil) P1664 P1665 Microbiological and molecular analysis of human invasive Streptococcus suis isolates A. Bojarska* (Warsaw, Poland), E. Molska, E. Stefaniuk, W. Hryniewicz, E. Sadowy The effects of zinc on methicillin-resistant Staphylococcus aureus in swine production: a randomised-controlled trial M. Slifierz* (Guelph, Canada), R. Friendship, J.S. Weese POSTER SESSION VI: New quinolones, oxazolidones, and a chimera of both P1666 In vitro activity of topoisomerase inhibitor GSK2140944 against Legionella pneumophila J. Dubois* (Sherbrooke, Canada), M. Dubois, J.-F. Martel, D.L. Butler P1667 AZD0914: establishment of preliminary quality control ranges against bacterial reference strains S. Patey* (Waltham, United States), L. Otterson, M. Huband P1668 Zabofloxacin for the treatment of mild to moderate community-acquired bacterial pneumonia compared to moxifloxacin; a phase 2 study G. Tillotson* (Downingtown, United States), Y.S. Kim, M.J. Kim, K.R. Baek, C.H. Lim, J. Rock, D.R. Choi P1669 Efficacy of the investigational fluoroquinolone finafloxacin against resistant staphylococci as compared to ciprofloxacin, levofloxacin, and moxifloxacin I. Morrissey, S. Hawser, A. Vente* (Berlin, Germany), A. Dalhoff P1670 Ecological and pharmacodynamic effects of MCB3681 on skin, nasal, oropharyngeal and intestinal microbiota M.U. Rashid, A. Dalhoff, T. Kapsner, T. Bäckström, L. Björkhem Bergman, G. Panagiotidis, A. Weintraub, C.E. Nord* (Stockholm, Sweden) P1671 Mode of action of MCB3681 – analysis of MCB3681 proteome signature A. Dalhoff* (Kiel, Germany), B. Voigt, T. Kapsner P1672 Linezolid use in bone and joint infection in a tertiary care centre R. Buzelé* (Tours, France), F. Bastides, X. Pourrat, P. Rosset, J. Druon, G. Gras, L. Bernard P1673 In vitro activity of tedizolid against Staphylococcus aureus and linezolid-resistant Gram-positive cocci H. Chen, W. He, Q. Yang, W. Wu, Q. Wang, H. Li, C. Zhao, X. Wang, Y. Zhang, H. Wang* (Beijing, China) 24th ECCMID / Barcelona Final Programme 229 Posters P1660 Evolution of methicillin-resistant Staphylococcus aureus (MRSA) ST398 isolates infecting or colonising patients in a Spanish hospital: genotypes and clinical features M. Camoez* (Barcelona, Spain), J. Cámara, F. Tubau, M. Pujol, M.A. Domínguez Poster Area Chairs, Speakers & Authors P1659 Low prevalence of livestock-associated Staphylococcus aureus CC398 in a rural area of Greece S. Sarrou* (Larissa, Greece), A. Liakopoulos, S. Xytsas, C. Chatedaki, K. Pantelidi, A. Mavroidi, E. Prifti, I. Spiliopoulou, K. Tzanetou, E. Petinaki 12:30 – 13:30 Exhibition P1658 Prevalence of methicillin-resistant Staphylococcus spp. in Lithuanian dogs – a cross sectional study M. Ruzauskas* (Kaunas, Lithuania), N. Couto, J. Zymantiene, L. Vaskeviciute, R. Siugzdiniene, I. Klimiene, M. Virgailis, R. Mockeliunas, C. Pomba General Information P1657 Poster Sessions Tuesday, 13 May 2014 P1674 Longitudinal comparison of the in vitro activities of tedizolid and linezolid against Staphylococcus aureus clinical isolates from Europe (2009-2013) D. Sahm, D. Draghi, P. Bien* (San Diego, United States), K. Bartizal P1675 Changes in intestinal flora during 7-day tedizolid phosphate administration in a phase I study in healthy Japanese subjects T. Tanaka* (Osaka, Japan), Y. Hayashi, K. Okumura, K. Yoshikawa, M. Kato, K.T. Kanatani, I. Ikushima P1676 P1677 Activity of cadazolid and comparators against recent clinical isolates of Clostridium difficile determined by the CLSI agar dilution and broth microdilution methods I. Morrissey, S. Hawser* (Epalinges, Switzerland), H. Locher Drug development of new N-methylthioazetidinones and linezolid-like compounds active against Staphylococcus aureus isolated from cystic fibrosis patients: in vitro and in vivo biological evaluation R. Musumeci* (Milan, Italy), G. Sancini, A. Bulbarelli, D. Oggioni, M. Madeo, C. Colombo, L. Cariani, A. Teri, P. Galletti, A. Tolomelli, L. Gentilucci, D. Giacomini, P. Gasco, C.E. Cocuzza 12:30 – 13:30 Poster Area P1682 In vitro activity of plazomicin and comparators against carbapenemase-producing Enterobacteriaceae clinical isolates I. Rodriguez-Avial* (Madrid, Spain), I. Pena, C. Rodriguez-Avial, J.J. Picazo 12:30 – 13:30 Poster Area POSTER SESSION VI: PK/PD of antifungals and miscellaneous antibacterials P1683 Pharmacodynamic evaluation of moxifloxacin in pleural space infections K. Chatzika, P. Kontou* (Thessaloniki, Greece), K. Manika, G. Pitsiou, E. Katsifa, I. Kioumis P1684 Pharmacokinetics and safety of letermovir, a novel anti-human-cytomegalovirus drug, in renally impaired patients D. Kropeit* (Wuppertal, Germany), J. Scheuenpflug, K. Erb-Zohar, H.-P. Stobernack, E.G.J. Hulskotte, A. Van Schanke, H. Zimmermann, H. Rübsamen-Schaeff P1685 Pharmacokinetic interactions between bedaquiline and rifampicin or rifapentine E.M. Svensson* (Uppsala, Sweden), S. Murray, M.O. Karlsson, K.E. Dooley P1686 Safety and pharmacokinetics of solithromycin in subjects with hepatic impairment B. Jamieson* (Chapel Hill, United States), S. Ciric, C. Rosiak, P. Fernandes POSTER SESSION VI: Pleuromutilins and aminoglycosides P1678 Antibacterial in vitro activity of novel extendedspectrum pleuromutilins against Gram-positive and -negative bacterial pathogens S. Paukner* (Vienna, Austria), H. Kollmann, K. Thirring, W. Heilmayer, Z. Ivezic-Schoenfeld P1687 Development of a population pharmacokinetic model characterising the tissue distribution of azithromycin in healthy subjects S. Zheng, P. Matzneller, M. Zeitlinger* (Vienna, Austria), L. Lesko, S. Schmidt P1679 In vitro metabolism and in vivo pharmacokinetics of novel extended-spectrum pleuromutilin antibiotics D.B. Strickmann* (Vienna, Austria), W.W. Wicha, H. Kollmann, Z. Ivezic-Schoenfeld P1688 Azithromycin suppresses effector functions of CD4+ T-cells via inhibition of mTOR signalling K. Schmetterer* (Vienna, Austria), F. Ratzinger, G. Hoermann, H. Haslacher, W. Poeppl, H. Burgmann P1689 Complete in vitro adsorption of anti-infective drugs to an extracorporeal cytokine filter C. König* (Hamburg, Germany), A.C. Röhr, O.R. Frey, A. Köberer, A. Nierhaus, C. Langebrake, S. Kluge, A. Brinkmann P1690 Bell-shape dose-response of human IgG1, in murine models of infections: a human in-mouse artifact for SAR279356 A. Rey* (Toulouse, France), C. Perrin, C. Cantalloube, A. Deslandes, Y. Su, B. Rokbi, M. Mourez, L. Fraisse P1680 In vivo activity of extended-spectrum pleuromutilins in murine sepsis model W.W. Wicha* (Vienna, Austria), Z. Ivezic-Schoenfeld P1681 Extended-spectrum pleuromutilins: mode-ofaction studies S. Paukner* (Vienna, Austria), D.B. Strickmann, Z. Ivezic-Schoenfeld 230 24th ECCMID / Barcelona Final Programme Poster Sessions Tuesday, 13 May 2014 P1693 P1694 P1695 Two years’ experience and clinical performance in running an anti-fungal therapeutic drugmonitoring external quality assurance scheme M. Darville, A. Noel* (Bristol, United Kingdom), A. Lovering Single dose pharmacokinetics and penetration of micafungin into peritoneal fluid in postsurgical patients with nosocomial peritonitis S. Grau, S. Luque* (Barcelona, Spain), U. Rodriguez, N. Campillo, E. Salas, E. Samsó Pharmacokinetics of 100 mg/d of micafungin in patients with severe burn injuries M.J. Asensio, M. Sánchez, B. Galván, E. Herrero, L. Cachafeiro, A. Agrifoglio* (Madrid, Spain), E. Perales, S. Luque, A. Garcia de Lorenzo 12:30 – 13:30 Poster Area POSTER SESSION VI: PK/PD of antibiotics against Gram-positives P1701 Impact of weight distribution on the dosage and costs of daptomycin IV compared with ceftaroline fosamil for treating Welsh adult cSSTI patients with suspected MRSA D. Collomb, A. Lee, H. Vioix, T. Mepham* (Luton, United Kingdom) P1702 Population pharmacokinetic modelling and simulations to support dosing of daptomycin in paediatric patients less than 3 months of age G. Chandorkar* (Lexington, MA, United States), P. Bokesch, J. Bradley, L. Pheng, N.H. Gosselin, M.S. Mouksassi P1703 Tedizolid plasma pharmacokinetics (PK) are comparable in obese and non-obese patients and healthy subjects S. Flanagan* (San Diego, United States), S.L. Minassian, J. Passarell, J. Fiedler-Kelly, P. Prokocimer P1696 Posaconazole dosing strategy in paediatric haematology patients K. Vanstraelen* (Leuven, Belgium), A. Colita, P. Annaert, P. Vermeersch, A. Augustijns, I. Spriet P1697 Decision-support software for accurate voriconazole dosing in paediatric patients M. Neely* (Los Angeles, United States), X. Fu, S. Liu, A. Margol, S. Louie, W. Hope P1704 Determination of vancomycin in human cerebrospinal fluid and serum by high-pressure liquid chromatography: a prospective study S.H. Shokouhi* (Tehran, Iran), I. Alavi Darazam P1698 Pharmacodynamics of the new azole isavuconazole in an Aspergillus fumigatus mouse infection model S. Seyedmousavi* (Nijmegen, The Netherlands), J.F. Meis, R.J.M. Bruggemann, W.J.G. Melchers, P.E. Verweij, J.W. Mouton P1705 Daptomycin plasma and CSF levels in patients with external ventricular drain (EVD)-related ventriculo-meningitis (VM) L. Baietto* (Turin, Italy), S. Piva, N. Latronico, T. Togni, G. Di Perri, A. D’Avolio P1706 P1699 Toxicity and efficacy differences between liposomal amphotericin B formulations in uninfected and Aspergillus fumigatus infected mice J. Olson* (Pomona, United States), D. Hahka, J. Schwartz, G. Jensen, J. Adler-Moore Correlation of vancomycin AUC24/MIC BMD target with treatment failure for infective endocarditis and line related methicillin-resistant Staphylococcus aureus bacteraemia N. Ghosh* (Liverpool, Australia), S. Van Hal, R. Chavda 24th ECCMID / Barcelona Final Programme 231 Posters A pharmacokinetic rationale for alternate dosing strategies of anidulafungin R.J. Brüggemann* (Nijmegen, The Netherlands), W.J.F. Van der Velden, C.A.J. Knibbe, A. Colbers, S. Hol, D.M. Burger, N.M.A. Blijlevens, J.P. Donnelly Novel molecular insights in the inhibitory potential of antifungal drugs on ATP-binding cassette transporters MRP1, MRP2, MRP3, MRP4, MRP5, P-gp, BCRP and BSEP V.J.C. Lempers* (Nijmegen, The Netherlands), J.J.M.W. Van den Heuvel, J.B. Koenderink, R.J.M. Brüggemann Chairs, Speakers & Authors P1692 P1700 Exhibition Predicting bacterial resistance using the time inside the mutant selection window: pros and cons A. Firsov* (Moscow, Russia), Y. Portnoy, E. Strukova, D. Shlykova, S. Zinner General Information P1691 Poster Sessions Tuesday, 13 May 2014 P1707 Vancomycin needs higher dosing in patients with neutropenia M. Haeseker* (Voerendaal, The Netherlands), S. Croes, C. Neef, C. Bruggeman, L. Stolk, A. Verbon P1708 Risk factors associated with high linezolid trough plasma concentrations L. Morata* (Barcelona, Spain), J.M. Gómez, L. Manzanedo, M. Brunet, G. Casals, C. De la Calle, N. Cobos-Trigueros, J.A. Martínez, A. Soriano, J. Mensa P1709 Linezolid overexposure as a haematological toxicity marker S. Luque* (Barcelona, Spain), B. Lopez Garcia, S. Ortonobes Roig, O. Ferrandez, E. Salas Sanchez, M. Basas, F. Alvarez-Lerma, S. Grau P1710 Augmented clearance of linezolid in the critically ill: cause for concern? O.R. Frey* (Heidenheim, Germany), T. Fuchs, S. Helbig, A. Köberer, A.C. Röhr, A. Brinkmann P1711 Pharmacokinetics of high dose daptomycin in haemodialysis J. Diolez* (Poitiers, France), G. Béraud, S. Belmouaz, N. Venisse, M.A. Bauwens, F. Bridoux P1712 P1713 P1714 P1715 232 Plasma and mediastinal concentrations following continuous infusion of oxacillin in critically ill patients with deep sternal wound infections following cardiac surgery N. Nesseler* (Rennes, France), M.C. Verdier, Y. Launey, A. Malherbe, M. Dermu, C. Piau, E. Flecher, O. Tribut, Y. Mallédant, P. Seguin A simple equation to calculate area under the curve to optimise drug dosing: daptomycin as a motivating example M. Pai* (Albany, United States), A. Russo, A. Novelli, M. Venditti, M. Falcone Impact of patient- and disease-related characteristics on plasma and target site pharmacokinetics of linezolid in four heterogeneous populations I.K. Minichmayr* (Berlin, Germany), A. Schaeftlein, M. Zeitlinger, C. Kloft In vitro characterisation of vancomycin as prerequisite for a microdialysis study in neonates D. Kauzor* (Berlin, Germany), S. Schröpf, C. Kloft 24th ECCMID / Barcelona Final Programme P1716 Tolerability, safety and pharmacokinetics in healthy subjects of single intravenous doses of AFN-1720, a prodrug of the staphylococcocalspecific antibiotic AFN-1252 B. Hafkin* (Toronto, ON, United States), N. Kaplan P1717 Preclinical pharmacokinetics and efficacy of AFN1720, a prodrug of the staphylococcocal-specific antibiotic AFN-1252 N. Kaplan* (Toronto, ON, Canada), B. Hafkin P1718 Oral bioavailability of tedizolid in healthy Japanese subjects in a phase I study T. Tanaka* (Osaka, Japan), Y. Hayashi, K. Okumura, K. Yoshikawa, M. Kato, K.T. Kanatani, I. Ikushima P1720 Pharmacokinetics and pharmacodynamics of MEDI4893, an investigational antiStaphylococcus aureus alpha toxin human monoclonal antibody, from a phase 1 randomised placebo-controlled study in healthy adult volunteers X. Yu* (Gaithersburg, United States), G.J. Robbie, Y. Wu, M. Esser, V. Mody, K. Jensen, H.I. Schwartz, M. Hernandez-Illas, H.S. Jafri P1721 Semi-mechanistic PK-PD modelling of drug interactions between vancomycin or linezolid combined with meropenem against Staphylococcus aureus S.G. Wicha* (Berlin, Germany), W. Huisinga, C. Kloft P1722 Cross-reactivity of telavancin with vancomycin immunoassays K. McConeghy* (Chicago, United States), D. Clark, P. Worboys, S. Barriere, K. Rodvold P1723 Pharmacokinetics of 7-day multiple-dose tedizolid phosphate in healthy Japanese subjects in a phase I placebo-controlled study T. Tanaka* (Osaka, Japan), Y. Hayashi, K. Okumura, K. Yoshikawa, M. Kato, K.T. Kanatani, I. Ikushima P1724 Evaluation of linezolid versus vancomycin, alone or combined with clarithromycin or rifampin, against isolates of coagulase-negative staphylococci in an in vitro PK/PD model of bacterial biofilm J. Badiola, M. Ruiz-Ruigomez, A. Peña, J. Hernández-Quero, J. Parra Ruiz* (Granada, Spain) P1725 Nephrotoxicity of telavancin in an animal model V.H. Tam* (Houston, United States), K.R. Ledesma, D.R. Bowers, L.D. Truong Poster Sessions Post-antibiotic effect (PAE) and post-betalactamase-inhibitor effect (PLIE) of ceftazidime, ceftaroline and aztreonam, alone and in combination with avibactam against target Gramnegative organisms with extended-spectrum beta-lactamases C.M. Pillar* (Kalamazoo, MI, United States), A. Stoneburner, D.L. Shinabarger, K. Krause, W.W. Nichols P1735 In vivo pharmacodynamics of ceftolozane against Streptococcus pneumoniae and Pseudomonas aeruginosa across a wide range of MICs in a neutropenic murine thigh infection model D. Andes* (Madison, United States), L. Alex P1736 Pharmacodynamics of tazobactam combined with cefepime in a neutropenic mouse thigh model M.J. Melchers* (Nijmegen, The Netherlands), A.C. Van Mil, C. Lagarde, J.W. Mouton P1737 Phase I, randomised single- and multiple-dose study of ceftaroline fosamil 600 mg every 12 h (60-min infusion) and every 8 h (120-min infusion) M. Sunzel, M. Kujacic, H. Broadhurst, J. Li, T. Edeki* (Wilmington, United States) P1738 Pharmacodynamic profiling of intravenous betalactams against Gram-negative isolates from bloodstream infections from a Brazilian hospital L.S.M. Cardinal, R.S. Macedo, L.G. Cabral, J.P. Meneses, V.G. Monteiro, P.A.M. Neto, M.R.E. Araújo, A.S. Duarte, G.H. Furtado* (São Paulo, Brazil) P1739 Predictors of fluoroquinolone resistance in Pseudomonas aeruginosa: area under the curve related to either MIC or the mutant prevention concentration E. Strukova* (Moscow, Russia), D. Shlykova, Y. Portnoy, S. Zinner, A. Firsov In treatment of Pseudomonas aeruginosa with piperacillin tazobactam, addition of low dose gentamicin markedly reduces emergence of resistance and increases antibacterial effect A. Cochrane* (Bristol, United Kingdom), K. Bowker, A. Noel, A. MacGowan P1740 Use of cefepime against P. aeruginosa in a murine pneumonia model G. Drusano* (Lake Nona, United States), W. Liu, S. Fikes, N. Robbins, S. Kurhanewicz, J. Rodriguez, D. Baluya, A. Louie Exploring PK/PD relationship of a novel betalactamase inhibitor MK-7655 in combination with imipenem in a hollow fibre infection model J. Wu* (Kenilworth, NJ, United States), F. Racine, M.L. Rizk, M.K. Wismer, P. Harradine, K. Young, M. Motyl P1741 Protein binding of ertapenem in plasma from healthy volunteers and from ICU patients A. Kratzer, U. Liebchen* (Regensburg, Germany), S.G. Wicha, F. Kees, M.G. Kees 12:30 – 13:30 Poster Area POSTER SESSION VI: PK/PD of antibiotics against Gram-negatives P1727 P1728 P1729 Penetration of colistin into central nervous system in critically ill patients with proven or suspected central nervous system infections S. Luque* (Barcelona, Spain), L. Sorli, F. Alvarez-Lerma, N. Campillo, M. Basas, J.P. Horcajada, H. Knobel, M. Montero, E. Salas, S. Grau Pharmacokinetics of colistin methanesulfonate (CMS) in burns patients L. Baietto* (Turin, Italy), A. D’Avolio, S. Corcione, V. Malvasio, G. Di Perri, M. Stella, F.G. De Rosa Tissue exposure kinetics of colistin sulfate in a neutropenic mouse thigh model R. Singh* (Waltham, MA, United States), K. Farrington, A. Sathe, A. Gupta, M. Hale, G. Kern P1730 Polymyxin B: can we create a better product? Z. Kassamali* (Santa Monica, United States), P.R. Rhomberg, R.N. Jones, L.H. Danziger, R.A. Prince P1731 Methionine ameliorates polymyxin-induced nephrotoxicity in mice J. Wang, M.A.K. Azad, R.L. Nation, K.D. Roberts, P.E. Thompson, T. Velkov, J. Li* (Melbourne, Australia) P1732 P1733 24th ECCMID / Barcelona Final Programme 233 Chairs, Speakers & Authors P1734 Exhibition Pharmacokinetic/pharmacodynamic (PK/PD) profile of oral amoxicillin in elderly patients with Gram-positive infections requiring prolonged antimicrobial courses L. Pagani* (Bolzano, Italy), V. Vitrat, C. Janssen, F. Jehl, A. Renzoni, J. Gaillat, J.P. Bru General Information P1726 Posters Tuesday, 13 May 2014 Poster Sessions Tuesday, 13 May 2014 P1742 Population pharmacokinetic and pharmacodynamic analysis of metronidazole in Japanese patients with intra-abdominal infections and pelvic inflammatory disease N. Takenaka* (Shibuya-ku, Japan), S. Shoji, Y. Tomono P1743 Pharmacokinetic-pharmacodynamic (PK-PD) target attainment (TA) analyses supporting the selection of in vitro susceptibility test interpretive criteria for ceftolozane/tazobactam (TOL/TAZ) against Pseudomonas aeruginosa M. Melhem, A. Forrest, C. Rubino, S. Bhavnani, J. Steenbergen, G. Krishna, P. Ambrose* (Latham, United States) P1744 P1745 P1746 P1747 Monte Carlo simulation to evaluate the probability of attaining targeted pharmacodynamic exposure of ceftaroline fosamil against pathogens associated with CAP and SSTI in Europe A. Rodríguez-Gascón* (Vitoria, Spain), A. Isla, A. Canut Pharmacokinetic/pharmacodynamic analysis of moxifloxacin in patients with diabetic foot infections S.G. Wicha* (Berlin, Germany), K. Zink, T. Haak, F. Kees, C. Kloft, M.G. Kees Use of Bayesian pharmacokinetic models to predict meropenem concentrations in critically ill patients – application to therapeutic drug monitoring A. Farkas, G. Wong, G. Daroczi, J. Lipman, J. Roberts* (Queensland, Australia) Plasma and subcutaneous tissue pharmacokinetics of piperacillin in a large cohort of critically ill patients with sepsis M. Abdul-Aziz* (Brisbane, Australia), A. Udy, S. Wallis, M. Roberts, J. Lipman, J. Roberts 12:30 – 13:30 234 A novel molecular-based diagnostic screening test utilising the NanoChip® microarray technology for simultaneous detection of major sexually transmitted infections Z. Greenberg* (Ashdod, Israel), M. Fridlender, R. Sabban-Amin, Y. Mali, J. Kopelowitz 24th ECCMID / Barcelona Evaluation of Anyplex™ II multiplex real-time PCR for the diagnosis of seven bacterial sexually transmitted infections M. Strauss* (Afula, Israel), Z. Samra, A. Adawi, D. Sagas, R. Colodner P1750 Evaluation of a new multiplex PCR assay for the diagnosis of sexually transmitted infections pathogens in Rwanda C. Muvunyi* (Huye, Rwanda), N. Dhont, R. Verhelst, M. Reijans, G. Simons, G. Claeys, E. Padalko P1751 Culture and semi-quantitative PCR for urogenital mycoplasma and ureaplasma from ESwab™ transport medium M. Altwegg* (Lucerne, Switzerland), D. Danioth, M. Affolter, S. Pranghofer, M. Hug P1752 Evaluation of ESwab™ and an automated extraction for detection of Chlamydia trachomatis, Neisseria gonorrhoeae and Mycoplasma genitalium with the Bio-Rad Dx CT/ NG/MG® real-time PCR assay D. Ursi* (Antwerp, Belgium), H. Goossens, M. Ieven P1753 Evaluation of new HyBeacon-based PCR assays for the direct detection of Chlamydia trachomatis and Neisseria gonorrhoeae U. Eigner* (Heidelberg, Germany), M. Weizenegger, D. Bertsch, A. Veldenzer, M. Holfelder P1754 Prediction of gonococcal fluoroquinolone susceptibility from residual NAAT specimens using an allelic discrimination assay M.J. Pond* (London, United Kingdom), V. Miari, K. Laing, H. Jagatia, I. Monahan, T.D. Planche, P.D. Butcher, S.T. Sadiq P1755 Detection of Chlamydia trachomatis and Neisseria gonorrhoeae in dry vaginal and rectal swabs with the GMT PrestoPLUS assay compared to the Roche LightCycler® 4800 system S.A. Morré* (Amsterdam, The Netherlands), J.H. Dubbink, D.J. De Waaij, H. Struthers, J.A. McIntyre, P.P.H. Peters, S. Ouburg P1756 Optimisation and prospective 2-year evaluation of the detection of Chlamydia trachomatis and Neisseria gonorrhoeae in semen specimens using the Abbott realtime CT/NG assay F. Grattard* (Saint Etienne, France), P.O. Verhoeven, A. Carricajo, N. Fonsale, B. Pozzetto Poster Area POSTER SESSION VI: Molecular diagnosis of sexually-transmitted pathogens P1748 P1749 Final Programme Poster Sessions Tuesday, 13 May 2014 P1759 A case-control study of the prevalence of Ureaplasma spp. in symptomatic and asymptomatic patients: is non-quantitative PCR a suitable method for the diagnosis of infection? M. Strauss* (Afula, Israel), B. Chazan, A. Adawi, D. Sagas, O. Nitzan, R. Colodner P1760 Lymphogranuloma venereum: an emerging problem in HIV-positive patients G. Gregori, I. Dal Conte, E. Burdino, M.G. Milia, T. Allice, T. Ruggiero, A. Lucchini, G. Di Perri, V. Ghisetti* (Torino, Italy) P1761 Evaluation of nucleic acid amplification testing (GEN-PROBE® APTIMA®) (NAAT) for Chlamydia trachomatis from ocular samples R.P. Kowalski* (Pittsburgh, PA, United States), L.M. Karenchak, C.M. Elnyczky, L.V. Raju, N. Ismail P1762 Diagnostics of Neisseria gonorrhoeae in oropharyngeal samples: what is the clinical relevance of detection of very low gonorrhoeal concentrations in these samples? P. Wolffs* (Maastricht, The Netherlands), G. Van Liere, J. Veugen, A. Dirks, N. Dukers-Muijrers, C. Hoebe P1766 Diagnosis of anal and oral human papillomavirus (HPV) infections in HIV-positive patients R. Santangelo* (Rome, Italy), R. Martucci, V. Prete, S. Digiambenedetto, L. Romano, A. Borghetti, A. De Luca, G. Delogu, R. Cauda, M. Sanguinetti P1767 Human papillomavirus (HPV) infection after colonisation M. Alvarez-Argüelles* (Oviedo, Spain), S. Rojo, M. De Oña, O. Oscar-Martínez, Y. Ruano, M. Torrents, M. Santiago P1768 Distribution of HPV-16 and HPV-18 geographic lineages in high-risk women in the VALHIDATE study, Lombardy region, northern Italy E.R. Frati* (Milan, Italy), E. Tanzi, M. Martinelli, S. Bianchi, F. Mazza, M. Fasolo, D. Colzani, E. Fasoli, G. Rizzardini, G. Orlando P1769 Detection of high-risk human papillomavirus E7 proteins I. Koch* (Munich, Germany), H. Pfister, S. Fehrmann, M. Kellner, C. Reichhuber, S. McNamara, T. Paper, A.M. Kaufmann, T. Agorastos, P. Jansen-Dürr, O. Böcher, E. Soutschek 12:30 – 13:30 Poster Area Posters Molecular epidemiology of four selected sexually transmitted pathogens E.M.L. Verhaegh* (Tilburg, The Netherlands), C. De Jong, C. Geurts, A.G.M. Buiting, J.J. Verweij Comparison of various molecular methods for detecting human papilloma virus from clinical specimens T.S. Kim* (Seongnam, Korea), Y.J. Hong, S.M. Hwang, K.U. Park, J.H. Song, E.C. Kim POSTER SESSION VI: Serological diagnosis of syphilis P1763 Evaluation of the Seegene Anyplex™ II HPV 28 detection assay D. Cook* (Vancouver, Canada), T. Chan, S. Utokaparch, W. Mei, D. Van Niekerk, K. Ceballos, T. Ehlen, G. Ogilvie, M. Krajden P1770 Value of a chemiluminescent microparticle immunoassay (CMIA) in neurosyphilis diagnosis J. Martinez-Lopez* (Pontevedra, Spain), M.J. Zamora, R. Tato, S. Pérez-Cahafeiro, M.A. Pallares, S. Cortizo, M. Trigo Daporta P1764 Novel NanoChip® XL-based molecular tests for screening and genotyping the most abundant human papillomavirus (HPV) high- and low-risk strains Z. Greenberg* (Ashdod, Israel), M. Lederkremer, E. Ron P1771 Consistency between Treponema pallidum particle agglutination assay and architect chemiluminescent microparticle immunoassay and characterisation of inconsistent cases Z.Y. Li* (Beijing, China) P1772 Evaluation of different confirmatory algorithms using seven treponemal tests on architect syphilis TP-positive/RPR-negative sera S. Jonckheere* (Ghent, Belgium), M. Berth, M. Van Esbroeck, S. Blomme, K. Lagrou, E. Padalko 24th ECCMID / Barcelona Final Programme 235 Chairs, Speakers & Authors P1758 P1765 Exhibition Detection of Treponema pallidum by polymerase chain reaction in ulcers: what is the best target? A. Gayet-Ageron* (Geneva, Switzerland), B. Charton, P. Sednaoui, G. Getaz-Jimenez, M. Tangomo, T. Ferry, S. Lautenschlager, M. Cavassini, T. Perneger, H. Salord General Information P1757 Poster Sessions Tuesday, 13 May 2014 P1773 Discordant results from syphilis screening I. Polo Vigas* (Pamplona, Spain), C. Martin Salas, X. Beristain Rementería, I. Suarez Ochoa, I. Escobar Martínez, I. Tordoya Titichoca, C. Ezpeleta Baquedano P1774 Evaluation of the new ELISA assay BioElisa Syphilis 3.1 J.E. Sanz, E. Rocha, M.A. Mor* (Barcelona, Spain) 12:30 – 13:30 P1781 Activity of ceftazidime-avibactam and comparators versus characterised ESBL-positive Gram-negative bacteria isolated in the European region: 2012 programme K. Kazmierczak* (Schaumburg, United States), S. Hickman, M. Hackel, R. Badal, D. Biedenbach, I. Morrissey, S. Bouchillon, G. Stone P1782 Activity of ceftazidime-avibactam versus Pseudomonas aeruginosa, including multipledrug resistant isolates in Europe – the 2012 INFORM programme S. Bouchillon* (Schaumburg, United States), D. Hoban, M. Hackel, R. Badal, I. Morrissey, D. Biedenbach, W. Nichols P1783 Activity of ceftazidime-avibactam and comparators versus characterised class-C betalactamase positive Gram-negative pathogens isolated globally in the 2012 international network for optimal resistance monitoring (INFORM) programme K. Kazmierczak* (Schaumburg, United States), S. Hickman, M. Hackel, R. Badal, D. Biedenbach, I. Morrissey, S. Bouchillon, W. Nichols P1784 Characteristics of patients and bacterial isolates associated with repeated episodes of bacteraemia caused by extended-spectrum beta-lactamase-producing Enterobacteriaceae C.H. Lee* (Kaohsiung, Taiwan), J.W. Liu P1785 Typing survey for important nosocomial pathogens using the SpectraCell RA® system H. Willemse-Erix* (Rotterdam, The Netherlands), T. Bakker-Schut, E. Van Engelen, A. Van Merode, G. Puppels Poster Area POSTER SESSION VI: MDR Gram-negatives – clinical observations P1775 Development of a clinical prediction model for infection or colonisation with multidrug-resistant bacteria in a general hospital: a case-control study P.V. Nascimento* (São José dos Campos, Brazil), L.G. Silva, P.R. Madureira P1776 Treatment of multidrug-resistant Pseudomonas aeruginosa bacteraemia (MDR-PAB) with intravenous colistin: a comparison with other guided therapies M. Montero* (Barcelona, Spain), L. Sorlí, S. Grau, C. Segura, J. Gómez, I. Haro Vázquez, H. Knobel, R. Terradas, F. Alvarez Lerma, J.P. Horcajada P1777 P1778 P1779 P1780 Pitt bacteraemia and APACHE II scores in predicting 30-day mortality in multidrugresistant Gram-negative bacteraemia W. Khong, T.M. Ng, D. Lye* (Singapore, Singapore) Tigecycline activity against enteric pathogens resistant to amikacin as determined from TEST program analysis over ten years – TEST 2013 S. Bouchillon* (Schaumburg, United States), D. Biedenbach, M. Hackel, R. Badal, S. Hawser, H. Leister-Tebbe Impact of extensive drug resistance on clinical outcomes in patients with Pseudomonas aeruginosa bloodstream infections M. Willmann* (Tübingen, Germany), I. Kuebart, M. Marschal, K. Schröppel, W. Vogel, I. Flesch, U. Markert, I.B. Autenrieth, F. Hölzl, S. Peter Developing and implementing antimicrobial treatment strategies against extensively drugresistant Acinetobacter baumannii (XDR-AB) infections R. Almaghrabi, C.J. Clancy, R. Shields, Y. Doi, B. Hao, M.H. Nguyen* (Pittsburgh, United States) 236 24th ECCMID / Barcelona Final Programme 12:30 – 13:30 Poster Area POSTER SESSION VI: Miscellaneous P1786 First report of four different Nocardia species causing pathology in humans M. Ercibengoa, M. Alonso, R. Figueroa, J.M. Marimon Ortiz de Zarate* (DonostiaSan Sebastian, Spain), E. Pérez-Trallero P1787 Aerococcus urinae isolates detected in Switzerland: epidemiology and characteristics of an underestimated uro-pathogen Y.N. Guilarte, S.N. Seiffert, A. Lupo, S. Droz, V. Perreten, A. Endimiani* (Berne, Switzerland) Poster Sessions Tuesday, 13 May 2014 P1790 P1791 P1792 P1793 P1794 P1795 A case-control study of exogenous endophthalmitis diagnosed at a Spanish hospital during a 13-year period M.A. Asencio* (Alcazar De San Juan, Spain), M. Huertas, R. Carranza, J.M. Tenias, J. Celis, F. Gonzalez-Del Valle Microbiological investigation and clinical significance of Alloscardovia omnicolens in human samples C. Isnard* (Caen, France), F. Guérin, R. Liehnard, M. Auzou, V. Cattoir Factors associated with 90-day mortality in patients with Staphylococcus lugdunensis bacteraemia in Japan: a case-control study Y. Ainoda* (Tokyo, Japan), S. Asahata, T. Fujita, Y. Hirai, K. Totsuka Clinical significance, bacterial identification and antimicrobial susceptibility of the emerging pathogen Helcococcus kunzii A. Vergne* (Caen, France), F. Guérin, R. Lienhard, A. Le Coustumier, M. Auzou, C. Daurel, C. Poyart, V. Cattoir Cancer and haematopoietic cell transplant patients drive fluoroquinolone-resistance in viridans group streptococci in a large tertiary medical care system J.R. Wierenga* (Palmerston North, New Zealand), S.M. Butler-Wu, A. Wald, S. Turner, Z. Stednick, S.A. Pergam Associated factors to a large nosocomial outbreak of a clonal strain of group A Streptococcus in a French hospital: a case-control study E. Seringe* (Paris, France), M. Cognet, I. Novakova, E. Hernandez, C. Manuel, C. Plainvert, C. Poyart, P. Astagneau 12:30 – 13:30 Poster Area POSTER SESSION VI: Miscellaneous of community pathogens and infections P1797 Community-associated infections caused by multidrug-resistant microrganisms in elderly outpatients M. Tinelli* (Sant’ Angelo Lodigiano, Italy), F. Luzzaro, S. Bracco, A. Anesi, G.M. Rossolini P1798 New aspects on anaerobes isolated from complicated intra-abdominal infections and their antimicrobial susceptibility – a Romanian study V. Cristea* (Bucharest, Romania), G. Neacsu, M. Duta, R. Gilca, L. Tudose, B. Ionescu P1799 Updated epidemiology for acute cholangitis using Tokyo Guidelines 2013 severity assessment H. Gomi* (Shimotsuke, Japan), T. Takada, S. Kiriyama, M. Yokoe, F. Miura, T. Tsuyuguchi, R. Higuchi P1800 Prognostic value of intra-operative bile cultures C. Armiñanzas* (Santander, Spain), D. Ferrer, A. Sánchez, T. Tigera, L.A. Herrera, J. Calvo, L. Martínez-Martínez, M. Gómez-Fleitas, M.C. Fariñas P1801 Acute biliary tract disease: microbiological and clinical findings L. Lozano García* (Murcia, Spain), R. Blazquez Garrido, C. Candel Pérez, A. Guarín Montes, A.B. Pérez Jiménez, R. Cesteros Fernández P1802 Food-borne outbreak of group A streptococcal pharyngitis in military base A. Hussein* (Zefat, Israel), Y. Aura P1803 Keratitis by Elizabethkingia meningoseptica: the first clinical case reported in Europe Y.O. Eremina* (Porto, Portugal), C. Pina-Vaz, M. Ribeiro, L. Figueira, J. Beato, M.J. Espinar P1804 Fever of unknown origin among Bulgarian population M. Baymakova* (Sofia, Bulgaria), I. Dikov, K. Plochev, G.T. Popov, R. Mihaylova-Garnizova, V. Kovaliova 24th ECCMID / Barcelona Final Programme Posters Elizabethkingia meningoseptica: outbreak of a carbapenemase-producing Gram-negative in a tertiary care adult intensive care unit; environmental colonisation and antibiotic selection pressure L.J. Bedford* (Cambridge, United Kingdom), D.L. Maslin, D.A. Enoch, N.M. Brown Molecular characterisation of an international clone of multi-resistant Bacteroides fragilis isolates J. Soki, M. Hedberg, E. Nagy* (Szeged, Hungary), E. Urban Chairs, Speakers & Authors P1789 P1796 237 Exhibition Staphylococcus epidermidis catheter-related bloodstream infection in critically ill patients: epidemiology, biofilm formation and risk factors I. Papadimitriou Olivgeri, N. Giormezis, M. Papadimitriou Olivgeris* (Patras, Greece), F. Fligou, A. Liakopoulos, K. Filos, M. Marangos, E. Petinaki, E. Anastassiou, I. Spiliopoulou General Information P1788 Poster Sessions Tuesday, 13 May 2014 P1805 Burdens and risk factors of infectious diseases in rural southwest Ghana in pregnant women and the correlations on neonates – a cross-sectional pilot study A.E. Gordon, F. Völker* (Göttingen, Germany), P. Cooper, G. Koethe, A. Uy, O. Zimmermann, U. Groß P1806 Epidemiological patterns and trends of notified diseases in Dubai 2009-2013 H. Hussain* (Baghdad, Iraq) P1807 P1808 P1809 Study on meningococcal carriage in Italian teenagers A. Neri* (Rome, Italy), G. Renna, A. Carannante, A.M. Barbui, M. Conte, M.P. Landini, M.L. Garlaschi, L. Rossi, I. Santino, P. Stefanelli Surveillance of invasive bacterial diseases (N. meningitidis, H. influenzae, S. pneumoniae) and evaluation of vaccine coverage in 7 italian regions, 2008-2012 F. D’Ancona, M. Cerquetti, A. Pantosti, M. Caporali, C. Fazio, F. D’Ambrosio, M. Giufrè, M. Pompa, P. Stefanelli* (Rome, Italy) Day care clinics (DCC) for acute infectious diseases: an alternative to conventional hospitalisation; a quasiexperimental intervention study: preliminary results L. Llobera Rius* (Badalona, Spain), M.L. Pedro-Botet, L. Mateu, V. Isernia, M.J. Dominguez, J.M. Modol, P. Plana, M. Sabrià 12:30 – 13:30 P1812 Polymorphisms in cytokine genes IL6, TNF, IL10, IL17A and IFNG influence susceptibility to complicated skin and skin structure infections M.H.T. Stappers* (Nijmegen, The Netherlands), Y. Thys, M. Oosting, T.S. Plantinga, M. Ioana, P. Reimnitz, J.W. Mouton, M.G. Netea, L.A.B. Joosten, I.C. Gyssens P1813 Clinical management patterns in hospitalised patients with complicated skin and soft tissue infections (cSSTI) in Belgium: results from the REACH observational cohort study F. Jacobs* (Brussels, Belgium), B. Vandercam, S. Cherifi, M. Moutschen, P. Jorens, A. Vankeirsbilck P1814 Targeted antibiotic therapy combined with conservative surgery in the treatment of recurrent diabetic foot infection R. Luzzati* (Trieste, Italy), C. Rosin, D. Giacomazzi, M. Menoncello, M. Borelli P1815 Staphylococcus pseudintermedius not as rare a zoonosis as previously reported J. Lee* (Truro, United Kingdom), R.P. Bendall, M. Vos, L. Zhang, A. Murray, W. Gaze P1816 Monobacterial necrotising fasciitis observed in immunocompetent patients T. Kalo, A. Pilaca, K. Shkurti, B. Zama, E. Puca* (Tirane, Albania), E. Qyra, D.H. Kraja P1817 Skin and soft tissue infections by Staphylococcus lugdunensis A. Escudero-Jimenez* (Albacete, Spain), J. Galán-Ros, I. Beltrán-Cifuentes, J. Bartolomé-Álvarez, E. Escribano-Garaizábal, M.D. Crespo-Sánchez P1818 Geographic differences in the presentation and outcomes of acute bacterial skin and skin structure infections (ABSSSI) in the DISCOVER program S. Puttagunta* (Branford, CT, United States), G. Talbot, M. Wilcox, H. Boucher, M. Dunne P1819 Clinical presentation and outcomes by subtype of infection in patients with acute bacterial skin and skin structure infections (ABSSSI) in the DISCOVER program S. Puttagunta* (Branford, CT, United States), G. Talbot, M. Wilcox, H. Boucher, M. Dunne Poster Area POSTER SESSION VI: Skin and soft tissue infections and diabetic food P1810 Recurrent erysipelas, risk factors and clinical presentation – a retrospective cross-sectional study M. Inghammar* (Lund, Sweden), M. Rasmussen, A. Linder P1811 Pilot randomised controlled trial of short course intravenous antibiotic therapy for erysipelas and cellulitis of the lower limb N.D. Friedman* (Geelong, Australia), J. Pollard, A.L. Walton, D.P. O’Brien, R. Cowan, K. Lim, S. Huffam, S. Lane, A.J. Hughes, E. Athan 238 24th ECCMID / Barcelona Final Programme Poster Sessions P1828 Guidelines had a limited influence on the management of urinary tract infections by general practitioners A. Seve* (Poitiers, France), M. Garcia, G. Le Moal, C. Godet, F. Roblot, G. Béraud P1821 Risk-factor assessment of amputation in diabetic foot B. Dede, A. Kadanali, G. Karagoz, S. Comoglu, L. Gorenek* (Istanbul, Turkey) P1829 Assessment of urinary tract infections in a tertiary care hospital in Turkey C. Ataman Hatipoglu* (Ankara, Turkey), T. Ilgar, C. Bulut, D. Cerçioglu, S. Kinikli, A.P. Demiröz P1822 Wound-conditioning using negative pressure wound therapy and octenidine-containing wound irrigation solution in pressure ulcer patients: in vitro results and clinical outcome J. Matiasek* (Vienna, Austria), G. Djedovic, R. Pauzenberger, U. Rieger P1830 Differential characteristics of healthcareassociated compared to community-acquired febrile urinary tract infections in men A. Smithson* (Santa Coloma Gramenet, Spain), J. Ramos, N. Jové, R. Porron, M.T. Bastida P1831 P1823 Clinical features of diabetic foot osteomyelitis and risk factors for lower limb amputation L. EunJung* (Seoul, Korea), K. Seong Soon, K. Tae Hyong, C. Eun-Joo, J. Min Hyuk Evaluation of urinary tract infection in elderly patients hospitalised in an infectious diseases clinic N. Ozgur Aykin* (Eskisehir, Turkey), P. Korkmaz, Y. Alpay, M. Gulduren, F. Cevik Caglan P1832 Risk factors for the acquisition of ESBL-producing Enterobacteriaceae among patients with community-acquired urinary tract infections A. Aouam, A. Toumi* (Monastir, Tunisia), Y. Kadri, H. Ben Brahim, C. Loussaief, H. Ben Abdallah, M. Chakroun P1833 A randomised clinical trial study comparing a triple drug regimen in two different durations for treatment of patients with uncomplicated brucellosis M. Sofian, A. Aghakhani, A.A. Farazi, M. Banifazl, A. Ramezani* (Tehran, Iran) P1834 Brucella bacteraemia at King Fahad Medical City, Riyadh, Saudi Arabia T. Sulaiman* (Riyadh, Saudi Arabia), K. Baba, O. Al Hassar, M. Enani, A.A. Chentoufi Poster Area POSTER SESSION VI: Various clinical infections P1824 Infectious spondylodiscitis: a 3-year experience at the University Hospital of Modena, Italy A. Bedini* (Modena, Italy), C. Puzzolante, M. Meschiari, S. Zona, E. Franceschini, M. Menozzi, M. Codeluppi, G. Orlando, F. Carli, C. Mussini P1825 Pyogenic spondylitis and discitis: a systematic review of clinical and microbiological characteristics M. Fernández Blest* (Valencia, Spain), C. Castellanos, A. Pérez, J. Lopez, E. Ballester, V. Abril, M. Garcia Deltoro, E. Ortega P1826 Review of diagnostic process for vertebral osteomyelitis: 122 cases over 13 years R. Hase* (Kamogawa, Japan), N. Hosokawa, Y. Otsuka, K. Muranaka, Y. Uwamino, D. Suzuki, T. Mikawa, S. Uno, K. Miyoshi P1835 Clinical brucellar hepatitis: the results of the Istanbul-3 study H. Erdem, D. Ozturk-Engin, S. Gencer* (Istanbul, Turkey), S. Kaya, A.I. Baran, A. Batirel, R. Tekin, M.K. Celen, A. Denk, B. Brucellosis study group P1827 Prospective evaluation of the incidence of haematogenous prosthetic joint infections (H-PJI) following bloodstream infections (BSI) S. Nguyen* (Tourcoing, France), M. Valette, A. Tone, P. Choisy, D. Descamps, E. Senneville P1836 Short-course treatment with ceftriaxone for leptospirosis: a retrospective study in a single centre in eastern France J.F. Faucher, C. Chirouze* (Besançon, France), B. Hoen, J. Leroy, L. Hustache-Mathieu, J.M. Estavoyer 24th ECCMID / Barcelona Final Programme 239 General Information 12:30 – 13:30 Chairs, Speakers & Authors Clinical presentation of acute bacterial skin and skin structure infections (ABSSSI) by baseline pathogen in the DISCOVER program S. Puttagunta* (Branford, CT, United States), G. Talbot, M. Wilcox, H. Boucher, M. Dunne Exhibition P1820 Posters Tuesday, 13 May 2014 Poster Sessions Tuesday, 13 May 2014 P1837 Staphylococcus aureus nasal colonisation among participants in an intervention trial with highdose vitamin D – a cross-sectional randomised controlled pilot study K. Olsen* (Tromsö, Norway), A.-S. Furberg, G.S. Simonsen, J.U.E. Sollid, R. Jorde P1838 Current immunoepidemiology of invasive Haemophilus influenzae type A disease M. Ulanova* (Thunder Bay, Canada), E.B. Nix, R.S.W. Tsang, A. Cerqueira, W. McCready P1839 The aetiology of febrile illness in patients presenting to Chittagong Medical College Hospital in Chittagong, Bangladesh R.R. Maude, H.K. De Jong* (Amsterdam, The Netherlands), L. Wijedoru, M.A. Hossain, M.R. Karim, W.J. Wiersinga, A.M. Dondorp, S. Baker, M.A. Faiz, C.M. Parry P1840 An unnoticed origin of persistent fever: periapical tooth abscess F. Arslan* (Istanbul, Turkey), M. Yilmaz, A. Batirel, N. Ozer, N. Alpay, A. Mert P1841 Mortality and prognostic factors of Listeria monocytogenes infections A. Martinez, M.L. Fernandez, I. Piñero, J. Fernandez, C. Suarez, H. Gomez, D. Caravia, A. Rodriguez-Guardado* (Oviedo, Spain) P1842 P1843 P1844 Prior anti-inflammatory drug exposure and risk of peritonsillar abscess in children and adults: prospective multi-centre case-control study in 13 French university hospitals in 2009-2012 D. Lepelletier* (Nantes, France), V. Pinaud, P. Le Conte, C. Bourigault, N. Asseray, J. Caillon, C. Ferron, C. Righini, E. Batard, G. Potel P1845 Mediterranean spotted fever: case series over 24 years (1989 – 2012) P. Crespo* (Coimbra, Portugal), D. Seixas, N. Marques, J. Oliveira, J. Saraiva da Cunha, A. Meliço-Silvestre P1846 Case report of bilateral psoas abscess caused by Janibacter terrae W.Y. Wan* (Rhondda Cynon Taff, United Kingdom), K. Ward, A. Mughal P1847 Bacterial load and disease severity in ocular Chlamydia trachomatis infection in a trachomahyperendemic population A. Last* (London, United Kingdom), C. Roberts, E. Cassama, M. Nabicassa, S. Molina-Gonzalez, S. Burr, D. Mabey, M. Holland, R. Bailey P1848 The aetiologic agents and resistance patterns in complicated intra-abdominal infections: are they related to mortality? S. Kesim, N. Baykam* (Ankara, Turkey), A. Kocagul Celikbas, S. Eren Gok, A. Aypak, M.N. Eroglu, H. Esener, B. Dokuzoguz 12:30 – 13:30 Poster Area POSTER SESSION VI: Paediatric infections P1849 Hepatic cystic echinococcosis in children – always a challenge D. Iacob* (Cluj Napoca, Romania), O. Fufezan, M. Horvat P1850 Association between virulence genes, clinical presentation and outcome in patients with Streptococcus pyogenes infections L. Billon* (Toulouse, France), I. Collinson, A. Mari, C. Plainvert, M. Archambaud, J. Lourtet-Hascoet, N. Marty, C. Poyart, G. Marion Impact of a systematic multidiscipilinary approach on healthcare associated infection incidence in a cardiosurgical paediatric intensive care unit: an intervention study R. Netto, P. Bernaschi, M. Carletti, F.I. Calò Carducci, L. Gargiullo* (Rome, Italy), D. Roma, L. Romani, P. Cogo, M.L. Ciofi Degli Atti, P. D’Argenio P1851 Intra-amniotic infection: aetiology and adverse pregnancy outcome A. Vergara Gómez* (Barcelona, Spain), J. Bosch, Y. Zboromyrska, A. Rodríguez, I. Vives, T. Cobo, J.C. Hurtado, I. Alejo, M. Palacio, J. Vila Haemophagocytic lymphohistiocytosis secondary to visceral Leishmania, the first Italian report L. Gargiullo* (Rome, Italy), L. Gramatica, L. Romani, D. Roma, F.I. Calò Carducci, S. Bernardi, P. D’Argenio P1852 Severe invasive Streptococcus pyogenes infections in children: three cases C. Plainvert, I. Poilane, M. Pellan, M. Lescat, L. De Pontual, A. Collignon* (Bondy, France), C. Rousseau 240 24th ECCMID / Barcelona Final Programme Poster Sessions Hospitalisations for varicella and measles in children younger than 2 years in 2006-2011 in Italy: a cross sectional study utilising national hospital discharge database M. Sbarbati, A.C. Di Pietro* (Rieti, Italy) P1854 Epidemiology of acute gastroenteritis in hospitalised children in NW Greece during a 12year period C. Gartzonika, E. Priavali, P. Bozidis, A. Tatsi, D. Papamichail, N. Zotos, A. Kallinteri, G. Vrioni, S. Levidiotou* (Ioannina, Greece) P1863 P1855 Respiratory syncytial virus infection in children with severe motor and intellectual disabilities T. Hoshina* (Kitakyushu, Japan), S. Onoyama, I. Kenji, S. Honjo, T. Hara Daptomycin use in infants and children: preliminary results of a retrospective multicentre study of the Italian Society for Paediatric Infectious Diseases S. Garazzino* (Turin, Italy), E. Castagnola, C. Mosa, M. Di Gangi, S. Esposito, A. Nocerino, L. Galli, L. Lancella, C. Calitri, P.A. Tovo P1864 Evaluation of antibodies against Helicobacter pylori; an epidemiological study in symptomatic children vs children without gastrointestinal symptoms A. Psina, M. Matsas* (Athens, Greece), M. Papadimitriou, E. Vetouli, I. Paraskakis P1865 An analysis of microorganisms isolated from paediatric patients in a tertiary hospital in Korea, 2006 – 2012 S. Cho, H. Lee* (Jeonju, Korea) P1866 Determination of virulence factors, antimicrobial susceptibility and extended-spectrum betalactamase production rates of paediatric uropathogenic E. coli isolates K. Yilmaz* (Izmir, Turkey), S. Ermertcan, H. Tasli, S. Kurutepe P1867 The accuracy of multiplex-PCR in the diagnosis of bloodstream infections in neonates and infants aged less than 90 days L. Folgori, B. Lucignano, M. Carletti, C. Bertaina, L. Pansani, R. Monfortese, M. Muraca, P. Bernaschi* (Rome, Italy) P1868 A new approach to diagnosis of congenital toxoplasmosis in newborns V. Meroni* (Pavia, Italy), L. Bollani, M. Chiaretto, M. Gobbi, F. Genco P1869 Changing antibiotic susceptibilities of uropathogens isolated from paediatric patients in northern Italy between 2005 and 2012 R. Lo Bello, L. Pescetto, L. Ricagni, P. Morelli, A.M. Rabagliati, R. Bandettini* (Genoa, Italy) P1870 Infectious agents in congenital cataract in a tertiary care hospital in north India M. P Singh Bansal* (Chandigarh, India), J. Ram, A. Kumar, J. Khurana, M. Marbariang, R.K. Ratho P1856 P1857 P1858 P1859 Neonatal group B streptococcal meningitis in France (2001-2011) A. Perret, C. Joubrel, P. Bidet, S. Bonacorsi, C. Levy, J. Raymond, R. Cohen, C. Poyart* (Paris, France) Childhood brucellosis; an epidemiological, microbiological, and clinical study in a paediatric hospital in Greece M. Matsas* (Athens, Greece), M. Papadimitriou, E. Lebessi, A. Doudoulakakis, N. Palaiologou, I. Paraskakis The effects of nosocomial rotavirus gastroenteritis on the length of hospital stay and cost O. Ozgur, R. Tekin* (Diyarbakir, Turkey), S. Celik, Y. Palanci, A. Yazicioglu Prospective study of the correlation between the presence of viraemia and clinical severity during the 2011-2012 enterovirus 71 epidemic in Taiwan H.Y. Cheng* (Taipei, Taiwan), Y.C. Huang, T.Y. Yen, S.H. Hsia, Y.C. Hsieh, T.Y. Lin, L.Y. Chang, L.M. Huang P1860 Daptomycin for MRSE bacteraemia in neonates L. Michelim* (Caxias do Sul, Brazil), L. Dalcin, L. Wu, F. Chiaradia, M. Menegotto, B. Araujo, D. Nodari P1861 Fever evaluation practices in infants aged =60 days: a nationwide survey H. Yarden-Bilavsky* (Petah Tikva, Israel), S. Ashkenazi, J. Amir, Y. Schlesinger, E. Bilavsky 24th ECCMID / Barcelona Final Programme 241 Chairs, Speakers & Authors P1862 Exhibition Time to positivity of blood cultures for coagulasenegative staphylococci in neonates M. Macho Aizpurua, J.L. Díaz de Tuesta del Arco, L. Rodeño Fernández, R. Cisterna Cáncer* (Bilbao, Spain) General Information P1853 Posters Tuesday, 13 May 2014 Poster Sessions Tuesday, 13 May 2014 P1871 Clinical characteristics of rotavirus infection in a neonatal intensive care unit: a five-month survey during seasonal epidemic peak L. Gabrielli* (Bologna, Italy), M.G. Capretti, A. Orlandi, C. Marsico, M. De Angelis, A. Chiereghin, G. Piccirilli, F. Bellini, G. Faldella, T. Lazzarotto P1878 P1872 Development of a systematic surveillance system for viral diarrhoea in children M. Aravena Urrutia, C. Vizcaya* (Santiago, Chile), C. Martinez Valdebenito, L. Montecinos, T. Hirsch, A. Guzmán, M. Ferrés 12:30 – 13:30 12:30 – 13:30 P1879 Characteristics of AIDS patients in intensive care units: a retrospective study in the The Netherlands (1999-2013) M.A.M. Huson* (Amsterdam, The Netherlands), F. Bakhshi-Raiez, M.P. Grobusch, E. De Jonge, N.F. De Keizer, T. Van der Poll P1880 Incidence of de novo tumours in HIV-infected liver transplant recipients: a multi-centre study F. Aguero* (Barcelona, Spain), C. Manzardo, J.I. Herrero, A. Valdivieso, M. Abradelo, M. Salcedo, S. Del Campo, A. Moreno, A. Rimola, J.M. Miro P1881 Retention in care and lost to follow-up in patients receiving antiretroviral treatment at Roosevelt Hospital in Guatemala City during the period 2001-2012 C. Mejia* (Guatemala City, Guatemala), R. Pinzon, J. Smayaoa, L. Garcia, M. Romero, E. Boror P1882 Incidence and long-term survival after acute myocardial infarction and stroke events in HIVinfected patients D. Gotti, E. Raffetti, L. Albini, G. Paraninfo, F. Castelnuovo, A. Ferraresi, N. Brianese, F. Castelli* (Brescia, Italy), F. Donato, E. Quiros-roldan P1883 Epidemiological, clinical profile and longterm survival in a cohort of patients with Pneumocystis jirovecii pneumonia (PJP) in HIVinfected patients in the HAART era C. López Sánchez* (Barcelona, Spain), V. Falcó, J. Burgos, J. Navarro, A. Curran, I. Los Arcos, I. Sánchez, T. L. Larrainzar, M. Crespo, A. Pahissa P1884 Clinical and epidemiological features of psoriasis in HIV-infected patients R. Petre* (Bucharest, Romania), A. Hristea, R. Jipa, R. Moroti, C.M. Popescu, I. Niculescu, L. Cavaropol, V. Molagic, C. Tiliscan, V. Arama POSTER SESSION VI: Electronic and economic resources in infectious diseases Bibliometric analysis of European publications in infectious diseases and medical microbiology areas in 2012 O. Sipahi* (Izmir, Turkey), H. Sipahi, M. Tasbakan, H. Pullukcu, B. Arda, T. Yamazhan, S. Ulusoy P1874 Creating a nationwide platform for accessing antimicrobial guidelines and prescribing support on mobile devices in the UK using agile development O.J. Dyar* (Kidlington, United Kingdom), T. Lewis, R. Tilley, R. Baker, R. McMullan, P. Howard, S. Harbarth, C. Pulcini, C. Stålsby-Lundborg, D. Nathwani P1875 P1876 P1877 Innovative use of a modern array of electronic tools using available resources to run a twin site based outpatient parenteral antibiotic therapy [OPAT] service in north west England A. Guleri* (Blackpool, United Kingdom), R. Houlihan, R. Sharma, S. Rourke, S. Townson, M. Wong, N. Howcroft, A. Barber, J. Drinkwater, J. Ball Valuation of hospital bed-days released by infection control programmes: standard methods overestimate economic value A.J. Stewardson* (Geneva, Switzerland), S. Harbarth, N. Graves, TIMBER study group Funding infectious disease research: a systematic analysis of UK research investments by funders 1997-2010 J.R. Fitchett, M.G. Head* (United Kingdom), M.K. Cooke, F.B. Wurie, R. Atun 242 24th ECCMID / Barcelona Final Programme Poster Area POSTER SESSION VI: HIV infection – clinical profile Poster Area P1873 The lean approach to designing a new laboratory platform, and improving productivity, turnaround-times (TAT), efficiency and quality J. Marcisin* (Bratislava, Slovakia), M. Urbanek, H. Palumbo Poster Sessions Tuesday, 13 May 2014 Characteristics, incidence and mortality from lower respiratory tract infection in HIV patients over a 10-year period R. Perello* (Santa Coloma Gramenet, Spain), S. Camon, O. Escoda, N. Alcolea, A. Smithson Injection drug use influences T-cell distribution and CCR5 expression in HIV+ and ESN population E. Kallas* (Tartu, Estonia), R. Avi, K. Huik, S. Türk, M. Pauskar, E.-L. Jõgeda, M. Šunina, D. Des Jarlais, A. Uusküla, I. Lutsar P1893 Skin rash related to once-daily boosted darunavircontaining regimens in HIV-infected ethnic Chinese: incidence and associated factors K.Y. Lin* (Taipei, Taiwan), C.Y. Cheng, C.J. Yang, M.S. Tsai, S.M. Hsieh, H.Y. Sun, W.H. Sheng, M.Y. Chen, S.Y. Chang, C.C. Hung Different viral replication activities of HIV1 subtypes that were prevalent in Taiwan: findings from transfection and in vitro infection experiments F. Tseng* (Tainan, Taiwan), S. Wang, J. Wang, Y. Lin, L. Cheng, C. Wu, H. Lin, W. Ko P1894 Evaluation of a new high throughput automated chemiluminescence immunoassay for the simultaneous detection of human immunodeficiency virus antigens and antibodies D. Zanin, A. Pighini* (Saluggia, Italy), K. Scerbo Polverato, D. Greco, D. Tramontin, M. Calleri, L. Pallavicini P1895 HPV anal infection in HIV-positive men who have sex with men (MSM): a cross sectional and a longitudinal study over five years S.G. Parisi* (Padua, Italy), R. Scaggiante, A. Barelli, S. Andreis, C. Boldrin, F. Dal Bello, M. Cruciani, C. Mengoli, M. Basso, G. Palù P1896 A clinical lab experience with an automated HIV antigen /antibody (AG/AB) combined assay P. Huynen* (Liège, Belgium), F. Toussaint, C. Gérard, M.P. Hayette, C. Meex, J. Descy, P. Melin P1897 A new tool to assess bone quality is superior to densitometry to study bone toxicity in HIV patients R. Güerri Fernandez* (Barcelona, Spain), J. Villar-García, H. Knobel, A. Gonzalez Mena, J.L. Gimeno Bayon, D. Molina Morant, L. Vilaplana Marz, A. Diez Perez, J.P. Horcajada Gallego, E. Torres del Pliego P1898 Microbial translocation is associated with incomplete immune recovery in HIV-infected patients J. Villar* (Barcelona, Spain), J.J. Hernández, R. Güerri, E. Lerma, A. González, M.L. Sorli, M.M. Montero, A. Guelar, J.P. Horcajada, H. Knobel Probiotic effect on microbial translocation in HIVtreated patients: a placebo-controlled trial J. Villar* (Barcelona, Spain), J.J. Hernández, R. Guerri, E. Lerma, A. González, M.L. Sorli, M.M. Montero, A. Guelar, J.P. Horcajada, H. Knobel P1889 Admissions for pneumonia in HIV-positive patients – a one-year cohort study at a tertiary centre A. Almeida* (Lisbon, Portugal), S. Castelo Branco, Z. Vesza, R. Pereira P1890 Preliminary findings of a prospective study about aetiologic agents of community-acquired pneumonia in hospitalised patients with HIV infection C. Figueiredo Mello* (São Paulo, Brazil), M. Della Negra, A.S. Shafferman Levin Jarisch-Herxheimer reaction among HIV-infected patients with early syphilis: azithromycin vs benzathine penicillin G therapy M.S. Tsai, C.J. Yang, N.Y. Lee, S.M. Hsieh, Y.H. Lin, H.Y. Sun, W.H. Sheng, K.Y. Lee, W.C. Ko, C.C. Hung, E. Chang* (Taipei, Taiwan) 24th ECCMID / Barcelona Final Programme Posters POSTER SESSION VI: Laboratory and risk factors in HIV infection P1892 P1888 P1891 Poster Area Chairs, Speakers & Authors P1887 12:30 – 13:30 Exhibition P1886 The prognosis of HAART-treated HIV infected women in resource-limited settings from 19982012 in Belgrade, Serbia D.J. Jevtovic, D. Salemovic, J. Ranin, G. Dragovic Lukic, J. Jordovic* (Beograd, Serbia), I. Pesic Pavlovic, J. Kusic 243 General Information P1885 Poster Sessions Tuesday, 13 May 2014 P1899 Distribution of HLA-B antigens and HLA-B*57:01 allele associated with the B57.1 ancestral haplotype in HIV infected individuals G. Ocejo-Vinyals, C. Armiñanzas* (Santander, Spain), F. Ausín, S. Echevarría, M. Gutiérrez-Cuadra, M.C. Fariñas P1900 Dysfunctional gut microbiota is associated with chronic immune activation in HIV infection J.F. Vázquez-Castellanos* (Valencia, Spain), S. Serrano-Villar, A. Latorre, N. Madrid, T. Sainz, S. Ferrando-Martínez, S. Moreno, V. Estrada, M.J. Gosalbes, A. Moya P1907 Antiretroviral treatment is associated with increased arterial stiffness in sub-Saharan African HIV-1-infected patients: a cross-sectional study T. Msoka* (Moshi, Tanzania), Y. Smulders, A.M. Van Furth, G.P. Van Guilder, J.A. Bartlett, M.A. Van Agtmael P1908 Early diagnosis of HIV infection: an achievable objective M. Vera* (Madrid, Spain), M. Villa, M. Chamón, M. Grau, I. Calzas, R. Pérez, J. Ballesteros, J. Pérez, C. Rodríguez, J. Del Romero P1901 Prevalence of HIV among adolescents and young people requesting HIV testing in an STI clinic in Madrid C. Rodríguez* (Madrid, Spain), T. Puerta, P. Clavo, J. Balllesteros, M. Vera, S. Del Corral, N. Jerez, V. Paredes, I. Río, J. Del Romero P1909 Immunological biomarkers predictive of clinical response to chemotherapy and HAART maintenance in HIV+ patients with Kaposi’s sarcoma R. Tedeschi* (Aviano, Italy), M.T. Bortolin, E. Bidoli, E. Vaccher, P. De Paoli P1902 Intrauterine growth restriction in pregnancy due to HIV infection S. Cambrea* (Constanta, Romania), D. Tanase, M. Ilie, D. Carp, S. Halichidis, C. Petcu P1910 Analysis of baseline HIV-1 genotypes in naïve subjects with HIV in a correctional setting M. Badowski* (Chicago, United States), R. Werner, J. Young, P. Vaughn, L. Shicker, M. Patel P1903 Non-physician clinician provided HIV treatment with equivalent outcomes as physician-provided care: a meta-analysis C. Emdin* (Oxford, United Kingdom), N.C. Chong, P.E. Millson 12:30 – 13:30 Poster Area POSTER SESSION VI: Viral hepatitis and HIV/HCV co-infection P1904 Computer-based counselling and screening for risk of HIV transmission among blood donors in western Saudi Arabia A. AlThaqafi* (Jeddah, Saudi Arabia), F. Farahat, M. ALShamrani, A. AlAmri, A. AlSobhi, A. Farzal, K. Anger P1911 HIV-envelope protein gp120 and the chemokine receptor CCR5 interaction mediates activation of the NALP3-inflammasome complex in human hepatic stellate cells R. Bruno* (Pavia, Italy), A. Cappon, S. Gessani, A. Masotti, L. Maiocchi, F. Marra P1905 Transition to adult care in youth living with HIV: need for an adolescent-adapted dialogue D. Nicca* (St. Gallen, Switzerland), R. Schmidhaeusler, C. Rudin, C. Fehr, P. Vernazza, C. Kahlert P1912 P1906 Cardiovascular risk factors in HIV-infected young adults undergoing antiretroviral treatment F. Dumitrescu* (Craiova, Romania), A. Cupsa, L. Giubelan, D.M. Cupsa, A. Stoian, I. Niculescu, M. Jianu Safety and anti-HCV efficacy of an IFN-free, sofosbuvir plus ribavirin therapy in HIV/HCVcoinfected patients after liver transplantation A. Moreno* (Madrid, Spain), R. Barcena, M.j. Perez-Elias, S. Del Campo, C. Quereda, J.L. Casado, F. Dronda, A. Diaz, M.L. Mateos, S. Moreno P1913 Silibinin prior to triple therapy leads to end of treatment success in most difficult to treat HIV/ hepatitis C co-infected patients D. Braun, A. Rauch, N. Durisch, N. Eberhard, A. Anagnostopoulos, B. Ledergerber, R. Weber, J. Fehr* (Zurich, Switzerland) 244 24th ECCMID / Barcelona Final Programme Poster Sessions Tuesday, 13 May 2014 P1918 HCV 2k/1b recombinant strain among hepatitis C infected genotype 2 patients in Georgia M. Karchava* (Tbilisi, Georgia), L. Sharvadze, L. Gatserelia, N. Chkhartishvili, N. Dvali, L. Dzigua, E. Dolmazashvili, T. Tsertsvadze Current HCV genotype prevalence in a university hospital in Barcelona: comparison with data obtained in 2002 J. Costa* (Barcelona, Spain), A. Capon, Z. Mariño, S. Lens, M. Laguno, J. Mallolas, C. Muñoz, M.A. Marcos P1919 Hepatitis B and hepatitis C seroprevalence among blood donors in northern-central Bulgaria M. Karcheva* (Pleven, Bulgaria), S. Mihaylova, A. Surdzhiyska, N. Doseva, K. Hristova, K. Koleva P1920 Importance of hepatitis B and C screening among people who inject drugs in opiate substitution treatment – cross-sectional study S. Skocibusic* (Mostar, Bosnia and Herzegovina), M. Martinac, J. Nikolic, S. Grgic, M. Latincic P1921 Comparison of hepatitis C virus genotypes in different risk groups in Croatia J. Vranes* (Zagreb, Croatia), T. Vilibic-Cavlek, I. Gjenero-Margan, S. Zidovec Lepej, B. Retkovac, N. Beader, S. Ljubin-Sternak, A. Vince P1922 Prevalence of blood-borne infections among Bulgarian prisoners G. Popov* (Sofia, Bulgaria), K. Plochev, M. Baymakova, M. Pishmisheva, T. Popov P1924 Hepatitis E in pregnancy and childbearing age in Denmark, 2000-2013 H. Vestergaard* (Copenhagen, Denmark), K. Traeholt Frank, O. Clemmesen, S. Midgley, T. Koelsen Fischer P1925 Autochthonous hepatitis E cases: where does the virus come from? F. Loisy-Hamon* (La Chapelle Sur Erdre, France), G. Leturnier, B. Lebeau P1926 Avidity of specific immunoglobulin G for the detection of hepatitis E primarily infection O. Fedotcheva* (Nizhniy Novgorod, Russia), J. Pticina, E. Matveeva, A. Burkov, T. Ulanova, A. Obriadina P1927 Seroepidemiological survey of hepatitis E virus infection among haemodialysis nursing staff in Athens, Greece I. Elefsiniotis* (Athens, Greece), D. Topka, L. Theodosopoulos, M. Mavrouli, G. Vrioni, A. Tsakris P1928 Prevalence of hepatitis E in a tertiary care hospital K. Yanik, Y. Tanriverdi Cayci* (Ankara, Turkey), A. Karadag, U. Akbal, E. Yologlu, M. Gunaydin P1929 Hepatitis A virus (HAV) in the Mena region: a new challenge S. Ramia* (Beirut, Lebanon), N. Melhem, H. Rashidi, R. Talhouk P1930 Evolution of the molecular epidemiology of hepatitis A virus in France: analysis of 1944 cases observed from 2004 to 2012 M. Mace, E. Marchadier, A.m. Roque-Afonso* (Villejuif, France) P1931 Rapid tests have difficulties in detecting samples weakly positive for HBsAg S. Ruosaari* (Helsinki, Finland), R. Myllys, J. Suni, M. Lappalainen P1932 Serum cytokine profile in acute viral hepatitis B in adults M. Horvat* (Cluj Napoca, Romania), D. Tatulescu, C. Cismaru, A. Slavcovici, M. Muntean, M. Lupse, M. Valeanu, D. Iacob 24th ECCMID / Barcelona Final Programme Posters P1917 Tracking down the mid-20th century emergence of HIV-1: a cross-sectional study on the transmission of hepatitis C virus and human T-cell lymphotropic virus type 1 C. Hogan* (London, Canada), M.J. Dion, E. Frost, G. Giroux, J. Iles, O. Pybus, V. Ilunga, F. Behets, J. Pépin Occult hepatitis B virus infection incidence in south-east region of Turkey T. Müderris, O.S. Cirit* (Gaziantep, Turkey), T. Yazici 245 Chairs, Speakers & Authors P1916 Neutropenia in HIV-HCV co-infected patients treated with pegylated interferon alpha-2a and ribavirin M. Basso, M. Franzetti, R. Scaggiante, A. Sattin, C. Mengoli, M. Cruciani, M. Fiscon, T. Martello, G. Palù, S.G. Parisi* (Padua, Italy) P1923 Exhibition P1915 Factors associated with HCV-RNA rebound in HIV/ HCV-coinfected patients after initial response to triple therapy with HCV-protease inhibitors A. Moreno* (Madrid, Spain), C. Quereda, M.j. Perez-Elias, S. Del Campo, R. Barcena, M.l. Mateos, J.l. Casado, F. Dronda, A. Diaz, S. Moreno General Information P1914 Poster Sessions Tuesday, 13 May 2014 P1933 Extended hepatitis B infection complicated with febrile neutropenia: a case report A. Willke, M. Meric Koc* (Kocaeli, Turkey), E. Azak P1934 The incidence rate of hepatosteatosis in virus carriers with inactive hepatitis B F. Demircan* (Elazig, Turkey), N. Gozel, A. Denk, F. Kilinc P1935 Efficacy of HBV vaccination in paediatric liver transplant recipients A. Szyszkiewicz, K. Dzierzanowska- Fangrat, I. Jankowska, B. Kasztelewicz* (Warsaw, Poland), D. Dzierzanowska P1936 Presence of anti-HBs in blood donors over 10-22 years after HBV vaccination M. De Paschale, S. Latella, A. Gatti, B. Brando, M.T. Manco, L. Belvisi, D. Cagnin, T. Cerulli, A. Paganini, P. Clerici* (Legnano, Italy) P1937 Long-term follow-up of chronic HBV infected pregnant women after delivery: a single-centre, prospective study I. Elefsiniotis* (Athens, Greece), E. Vezali, D. Vrachatis, S. Hatzianastasiou, S. Pappas, G. Farmakidis, G. Vrioni, A. Tsakris P1938 Correlation between ALT values, HBV DNA viral load and hepatic stiffness in a population of HBV asymptomatic carriers E. Biliotti, M. Spaziante, C. Franchi, D. Palazzo, R. Esvan* (Rome, Italy), P. Perinelli, V. Gallinaro, S. Grieco, C. Furlan, G. Taliani P1939 Role of chemokines and their receptors in chronic hepatitis C virus infection O. Zorbozan, I. Kaleli* (Istanbul, Turkey), H. Turgut P1940 IFN-alpha receptor-1 upregulation in PBMC from HCV naïve patients carrying CC genotype; possible role of IFN-lambda E. Lalle, L. Bordi, C. Caglioti, A.R. Garbuglia, C. Castilletti, L. Taibi, F. Cristofari, M.R. Capobianchi* (Rome, Italy) P1941 P1942 Serum chemerin patterns in a cohort of chronic hepatitis C patients M. Radulescu* (Bucharest, Romania), V. Arama, D. Munteanu, C. Popescu, C. Tiliscan, R. Mihailescu, L. Papagheorghe, L. Golcea, A. Streinu-Cercel HLA class II genotyping in chronic HCV patients M. Moheb, F. Ghoneim, H. Abdel Salam, D. Alkafash, N. Hanafi* (Alexandria, Egypt), A. Zid 246 24th ECCMID / Barcelona Final Programme P1943 Estimation of drug costs for anti-HCV therapy in the Calabria region in the era of direct-acting antivirals from a cohort of patients experienced to peginterferon/ribavirin A. Strazzulla* (Catanzaro, Italy), C. Costa, V. Pisani, V. De Maria, F. Giancotti, S. Parisi, N. Marascio, E. Zicca, A. Focà, C. Torti P1944 Prevalence of natural resistance mutations to hepatitis C virus polymerase inhibitors in Spanish patients G. Reina-Gonzalez, A. Zapata* (Pamplona, Spain), C. Bustos, M. Ortega, B. Sangro, J.I. Herrero, J. Prieto, J.I. Riezu-Boj, M. Fernández-Alonso P1945 ITPA gene polymorphism and ribavirin induced anaemia in Egyptian patients with hepatitis C virus genotype 4 N. Nemr* (Ismailia, Egypt), R. Kishk, M. Mandour P1946 Expression of Mx1, OAS1, PKR (EIF2AK2) and TP53 genes during treatment of chronic HCV patients B. Swiatek, D. Januszkiewicz* (Poznan, Poland), J. Rembowska, I. Bereszynska, J. Wysocki, I. Mozer-Lisewska, A. Kowala-Piaskowska, J. Nowak P1947 Impact of IL18 gene polymorphism on response to antiviral therapy in chronic HCV genotype 4 M. Mandour* (Ismailia, Egypt), N. Nemr, R. Kishk, E. Ahmed P1948 Early HCV kinetics during dual therapy predict EVR in the absence of RVR: still a role for dual therapy? M. Tontodonati, V. Cento, M. Sciotti, D. Di Giammartino, F. Di Candilo, R. Monarca, J. Vecchiet, R. Prinapori, C. Perno, G. Parruti* (Chieti, Italy) P1950 Polymorphisms in hepatitis C virus core and IL28B genes predict rapid viral response and early viral response during treatment in chronic hepatitis C infected patients G. Oprisan* (Bucharest, Romania), S. Dinu, M.D. Teleman, P.I. Calistru, E. Ceausu, M. Voiculescu, E. Rusu, S. Ruta, C. Sultana, G. Cardos P1951 Interferon-gamma inducible protein 10 and soluble CD26 as prognostic markers for the treatment outcome in chronic hepatitis C virus infection S. Ruta, C. Sultana* (Bucharest, Romania), C. Grancea, S. Florescu, M. Voiculescu, G. Cardos, C. Hepgen Project, G. Oprisan Poster Sessions Triple therapy for chronic hepatitis C: real life clinical experience in Croatia I. Kurelac* (Zagreb, Croatia), V. Cajic, D. Dusek, N. Papic, A. Vince P1954 Allelic frequency of inosine triphosphatase gene polymorphisms in hepatitis C virus infected patients S. Gorriz-Pintado, J. Gil-Tomás, A. Burgos-Teruel, M. Borrás-Máñez* (Alzira, Spain), J. Colomina-Rodríguez P1955 Virological and histological features in HBeAgnegative chronic hepatitis B virus infection with persistently normal ALT Z. Hattab* (Sousse, Tunisia), S. Mrabet, S. Mansouri, W. Hachfi, E. Ben Jazia, A. Letaief P1956 Diagnostic value of serum YKL-40, TIMP-1, TIMP-2, MMP-2 and TGF-ß1 for hepatic fibrosis in patients with chronic hepatitis B K. Arslan* (Ankara, Turkey), C. Ataman Hatipoglu, C. Bulut, H. Uludag Altun, M. Alparslan Gönültas, S. Kinikli, A. Pekcan Demiröz P1957 Evaluation of the diagnostic accuracies of seven non-invasive fibrosis tests in patients with chronic hepatitis B virus infection K. Arslan* (Ankara, Turkey), C. Ataman Hatipoglu, C. Bulut, S. Kinikli, A. Demiröz Chairs, Speakers & Authors P1953 Exhibition IL28B polymorphism and virological response during 12 weeks of pegylated interferon and ribavirin treatment in Polish chronic hepatitis C patients B. Swiatek, D. Januszkiewicz, J. Rembowska, I. Bereszynska, I. Mozer-Lisewska, A. Kowala-Piaskowska, J. Wysocki, J. Nowak* (Poznan, Poland) 24th ECCMID / Barcelona Final Programme 247 General Information P1952 Posters Tuesday, 13 May 2014 List of Chairpersons NamePage NamePage NamePage A D I Aguado Garcia, Jose M. Akova, Murat Albajar, Pere Allerberger, Franz Almirante, Benito Andersen, Leif P. Andersson, Emmi Antonelli, Guido Arikan-Akdagli, Sevtap Ascioglu, Sibel Avsic Zupanc, Tatjana 31, 64 43, 69 51 60 59, 73 28 47, 60, 64 51 31, 45 57 33 B 55 31 50 54, 63 63 70 E Eloit, Marc Esposito, Susanna Evengard, Birgitta 51 68 35, 54 64 33, 43 28 29, 40 54 42, 63 53 43 29, 51 C Calandra, Thierry Calbo, Esther Canton Moreno, Rafael Capobianchi, Maria Rosaria Capua, Ilaria Carmeli, Yehuda Carratala, Jordi Cataldo, M. Adriana Cavling Arendrup, Maiken Chastre, Jean Chiodini, Peter Cisneros Herreros, Jose Miguel Cole, Michelle Cookson, Barry Cordonnier, Catherine Cornaglia, Giuseppe Couet, William Craig, William A. Cretu, Carmen-Michaela Croxatto, Antony 32 30 29 35, 63 36 71 43 74 57 69 63 74 39 52 67 57 51, 65 67 28 60 Final Programme Frank, Uwe Friedrich, Alexander W. 63 27, 63 28 34 41, 43 G Gales, Ana Garnacho-Montero, José Gascon, Joaquim Gavaldà, Joan Gavazzi, Gaetan Genton, Blaise Gerold, Stanek Giamarellou, Helen Gikas, Achilleas Giske, Christian G. Gniadkowski, Marek Gonzalez-Martin Julian Gräser, Yvonne Greub, Gilbert Grobusch, Martin P. Groll, Andreas H. Grundmann, Hajo Guinea, Jesus Gyssens, Inge C. 52 50 J Jans, Beatrice Jonjic, Stipan 51 31 Kahlmeter, Gunnar Kaiser, Laurent Kern, Winfried V. Kerr, Kevin G. Kluytmans, Jan A.J.W. Kortbeek, Titia M. Kuijper, Ed J. 48 58 30, 33 30 45 31, 41, 58 32, 43, 60 L 46 71 41 65, 67 27 56, 63 28, 33 52 34, 65 39 37 27, 67 51 48, 56 53, 58 72 36 45 40 H Harbarth, Stephan J. Harmsen, Dag Hawkey, Peter M. Hernandez Alvaro, Pascual Hirsch, Hans H. Horcajada, Juan P. Howard, Susan J. Huang, Susan S. Hussein, Khetam Ieven, Margareta Ijzerman, Ed P.F. K F Back, David Balkhy, Hanan Baquero, Fernando Beeching, Nicholas J. Benzonana, Nur Bessede, Emilie Bjarnsholt, Thomas Bonomo, Robert A. Böttger, Erik C. Bottieau, Emmanuel Bouza Santiago, Emilio Brown, Derek F.J. 248 24th ECCMID / Barcelona Dagan, Ron Dedic, Kanita de Jong, Birgitta Dettenkofer, Markus Dixon, Dennis M. Dryden, Matthew 59 36 57 53 45 52 72 65 65, 68 Lange, Christoph Lass-Flörl, Cornelia Laurent, Frederic Leblebicioglu, Hakan Lecuit, Marc Leegaard Truls, Michael Leibovici, Leonard Letaief, Amel Lewis, Kim Limaye, Ajit P. Lina, Gerard Lindahl, Karin Ljungman, Per Lo Cascio, Giuliana Lopalco, Pier Luigi López-Vélez, Rogelio Lucet, Jean-Christophe Lumbreras, Carlos 63, 67 29 34 39 46, 49 55 65 28 40 64 44, 52 46 48, 68 54, 69 70 51 39 32 List of Chairpersons NamePage NamePage NamePage M P T Magiorakos, Anna-Pelagia 52 Mainardi, Jean-Luc 75 Malhotra-Kumar, Surbhi 50 Manuel, Oriol 31 Marr, Kieren 67 Martinez, Jose Luis 47 Martinez Martinez, Jose Antonio 70 Martinez-Martinez, Luis 37 Martinez, Mikel J. 36 Martinez, Miriam José Alvarez 44 Maschmeyer, Georg 48, 64 Matuschek, Erika 51 Maver Vodicar, Polona 34 Menendez, Clara 56 Menichetti, Francesco 70 Miro, José M. 56, 59 Mondelli, Mario U. 30, 46, 64 Moran-Gilad, Jacob 63 Moro, Maria Luisa 51 Mouton, Johan W. 27 Muscat, Mark 55, 70 Pachon-Diaz, Jeronimo Pagani, Leonardo Pantaleo, Giuseppe Paolo, A. Grossi Pappas, Peter G. Patel, Robin Paterson, David L. Pea, Federico Peixe, Luisa M. V. Perez-Romero, Pilar Petersen, Eskild Petrosillo, Nicola Poirel, Laurent Poljak, Mario Poulakou, Garyfallia Pozniak, Anton Puel, Anne Pulcini, Céline Puoti, Massimo Orth, Dorothea Osterhaus, Albert D.M.E. Otelea, Dan Ozaras, Resat 74 39, 71 51 28, 46 Ramharter, Michael Rautelin, Hilpi Raymaekers, Marijke Read, Robert C. Rello, Jordi Richardson, Malcolm Rodrigo, Carlos Rodríguez-Baño, Jesús Roilides, Emmanuel 47 46 53, 63 55, 64 29, 45 51 66 48 69 S Salmon-Ceron, Dominique Savelkoul, Paul Seifert, Harald Seme, Katja Signore, Alberto Skov, Robert L. Solomkin, Joseph S. Stefani, Stefania Stone, Sheldon 28, 51 31, 41, 75 53, 69 60 50 67 57, 70 55 27 U Ullmann, Andrew J. Unemo, Magnus 60 39 V Vandekerckhove, Linos Vandenbroucke-Grauls, Christina Vandenesch, Francois van der Poll, Tom van de Sande-Bruinsma, Nienke Van Eldere, Johan Van Hengel, Arjon van Soolingen, Dick Vesikari, Timo Vila Estape, Jordi Villegas, Maria Virginia Vince, Adriana Vincent, Jean-Louis Viscoli, Claudio Viveiros, Miguel Vlieghe, Erika 69 57 34, 42 32 46 44 63 42, 69 63 48, 53 46 30, 64 39 68 27, 69 34 W Wai-Kuo Shih, James Weinbren, Michael Wieland, Ulrike Wiersinga, W. Joost Wilcox, Mark H. Willems, Rob 66 39 39 39 32 54 Z Zimmerli, Werner Zinkernagel, Annelies 39, 50 46, 50 Chairs, Speakers & Authors O R 58 27 56 44 39 67 Exhibition 31, 74 73 42 60 Tacconelli, Evelina Theuretzbacher, Ursula Tolstrup, Martin Torres, Carmen Trautmann, Matthias Tulkens, Paul M. 24th ECCMID / Barcelona Final Programme 249 General Information Nagy, Elisabeth Nation, Roger L. Norrby-Teglund, Anna Q Quinones, Dianelys N 64 27, 51 35 32 60 49 64 35 44, 63 58 30, 39, 71 56 39, 57 53, 56 29 59 57 40 69 3rd ESCMID Workshop on Professional Affairs in Clinical Microbiology and Infectious Diseases PA Workshop The Future of Clinical Microbiology and Infectious Diseases in Europe Ljubljana, Slovenia, 5–6 June 2014 Workshop Objectives • To review the status of the specialities, Clinical / Medical Microbiology and Infectious Diseases, across Europe. • To discuss initiatives to improve the organisational basis for medical practice in our disciplines. Register online for the PA Workshop in Ljubljana at www.escmid.org/PAworkshop14 Workshop Faculty Murat Akova, Ankara, TR Petra Apfalter, Linz, AT Bruno Baršic, Zagreb, HR Nicholas John Beeching, Liverpool, UK Nur Benzonana, Istanbul, TR Bojana Beovic, Ljubljana, SI Joana Cortez, Coimbra, PT Davorka Dušek, Zagreb, HR Paul Hunter, Norwich, UK Gunnar Kahlmeter, Växjö, SE Winfried V. Kern, Freiburg, DE Titia Kortbeek, Bilthoven, NL Truls Michael Leegaard, Lørenskog, NO Pier Luigi Lopalco, Stockholm, SE Polona Maver Vodicar, Ljubljana, SI Mario Mondelli, Pavia, IT Dan Otelea, Bucharest, RO José Artur Paiva, Porto, PT Hilpi Rautelin, Uppsala, SE Jesús Rodríguez-Baño, Seville, ES Gian Maria Rossolini, Florence, Siena, IT Katja Seme, Ljubljana, SI Chrysanthi Skevaki, Athens, GR Branka Stirn Kranjc, Ljubljana, SI Davor Štimac, Rijeka, HR Špela Štunf, Ljubljana, SI Evelina Tacconelli, Tübingen, DE Sotirios Tsiodras, Athens, GR Jos W. M. van der Meer, Nijmegen, NL Johan van Eldere, Leuven, BE Adriana Vince, Zagreb, HR Reinhard Zbinden, Zurich, CH Annelies Zinkernagel, Zurich, CH NameNumber A Aali, S.A. . . . . . . . . . . . . . . . . . . . . . . . . . O243 Aas, M. . . . . . . . . . . . . . . . . . . . . . . . . . .P1359 Aasnaes, B. . . . . . . . . . . . . . . . . . .P1094, P1547 Aatola, H. . . . . . . . . . . . . . . . . . . . . . . . . P1392 Abadia, E. . . . . . . . . . . . . . . . . . . . . . . . . P0884 Abaev, I. . . . . . . . . . . . . . . . . . . . . . . . . . eP163 Abalain, M.L. . . . . . . . . . . . . . . . . . . . . . . P0945 Abassi, M.S. . . . . . . . . . . . . . . . . . . . . . . .P1635 Abate, D. . . . . . . . . . . . . . . . . . . . . . O213, P1291 Abba, M. . . . . . . . . . . . . . . . . . . . . . . . . .P0237 Abbate, I. . . . . . . . . . . . . . . . . . . . . . . . . .P1402 Abbo, L. . . . . . . . . . . . . . . . . . . . . . . . . . . O241 Abd Alhalim, N. . . . . . . . . . . . . . . . . . . . . . O094 Abd El Haliem, N.. . . . . . . . . . . . . . . . . . . .P0871 Abd El Moety, A. . . . . . . . . . . . . . . . . . . . eP306 Abd El Rahman, N. . . . . . . . . . . . . . . . . . . .P0871 Abd Aziz, A. . . . . . . . . . . . . . . . . . . . . . . .eP551 Abd Rahman, R. . . . . . . . . . . . . . . . . . . . . eP551 Abdala, E. . . . . . . . . . . . . . . . . . . . . . . . . P0523 Abdel Mohsin, A. . . . . . . . . . . . . . . . . . . . . O094 Abdel Salam, H. . . . . . . . . . . . . . . . . . . . . P1942 Abdelgawad, M. . . . . . . . . . . . . . . . . . . . . P0993 Abdelkareem, A. . . . . . . . . . . . . . . . . . . . P0467 Abdelmalek, R. . . . . . . . . . . . . . . . . . . . . P0420 Abdiyeva, K. . . . . . . . . . . . . . . . . . P0421, P1629 Abdoli, A. . . . . . . . . . . . . . . . . . . . . . . . . .eP130 Abdool Karim, Q. . . . . . . . . . . . . . . . . . . . KL208 Abdoul, H. . . . . . . . . . . . . . . . . . . . . . . . P0068 Abdul Rahman, Z. . . . . . . . . . . . . . . . . . . .eP551 Abdul-Aziz, M. . . . . . . . . . . . . . . . . . . . . . P1747 Abdulmajed, H.A. . . . . . . . . . . . . . . . . . . . .O049 Abdulmajeed, A. . . . . . . . . . . . . . . . . . . . . O190 Abdul-Rahim, H. . . . . . . . . . . . . . . . . . . . .eP558 Abe, M. . . . . . . . . . . . . . . . . P0521, P1268, P1270 Abed-Eldaim, M. . . . . . . . . . . . . . . . . . . . . O008 Abedin, J. . . . . . . . . . . . . . . . . . . . . . . . . P0445 Aberle, S.W. . . . . . . . . . . . . . . . . . . . . . . P0482 Abgueguen, P. . . . . . . . . . . . . . . . . . . . . . P1452 Abid, D. . . . . . . . . . . . . . . . . . . . . . . . . . .eP122 Abid, L. . . . . . . . . . . . . . . . . . . . . . . . . . .eP122 Abidi, M. . . . . . . . . . . . . . . . . . . . eP376, P0087 Ableitner, O. . . . . . . . . . . . . . . . . . . . . . . .P1501 Aboguttaia, N.B. . . . . . . . . . . . . . . . . . . . .P0924 Abradelo, M. . . . . . . . . . . . . . . . . . . . . . . P1880 Abreu Fonseca, C. . . . . . . . . . . . . . . . . . . P0052 Abreu, A. . . . . . . . . . . . . . . . . . . . .eP184, eP199 Abreu, R. . . . . . . . . . . . . . . . . . . . . . . . . .P1640 Abreu-Yanes, E. . . . . . . . . . . . . . . . . . . . . P0398 Abril, V. . . . . . . . . . . . . . . . . . . . . . . . . . .P1825 Abu Jaoudeh, M.A. . . . . . . . . . . . . . . . . . . .eP531 Abu Sin, M. . . . . . . . . . . . . . . . . . . . . . . . P0559 Abubakar, I. . . . . . . . . . . . . . . . . . . . . . . .P0918 AbuBakar, S. . . . . . . . . . . . . . . . . . . . . . . P0438 Abulaila, A. . . . . . . . . . . . . . . . . . . . . . . . P0227 AbuOun, M. . . . . . . . . . . . . . . . . . . . . . . . P0172 Abu-Raddad, L. . . . . . . . . . . . . . . . . . . . . .eP558 Abutbul, A.. . . . . . . . . . . . . . . . . . . . . . . .P1342 Acar, A. . . . . . . . . . . . . . . . . . . . . . . . . . .P1549 Accogli, M. . . . . . . . . . . . . . . . . . . . . . . . .P1153 Achermann, Y. . . . . . . . . . . . . . . . . . . . . . P0202 Achouiti, A. . . . . . . . . . . . . . . . . . . . . . . . P0146 Achour, W. . . . . . . . . . . . . . . . . . . . . . . . .eP503 Acikgoz, G.. . . . . . . . . . . . . . . . . . . . . . . P0407 Ackerman, B. . . . . . . . . . . . . . . . . . . . . . . eP271 Acosta, A. . . . . . . . . . . . . . . . . . . . . . . . . P0237 Adam, H. . . . . . . . . . . . . . . . . . . . eP436, P1086 Adam, R. . . . . . . . . . . . . . . . . . . . . . . . . P0065 Adamczuk, M. . . . . . . . . . . . . . . . . P1135, P1140 Adams, M.D. . . . . . . . . . . . . . . . . . . . . . . P0706 Adamzik, M. . . . . . . . . . . . . . . . . . . . . . . .P0258 Adar, P. . . . . . . . . . . . . . . . . . . . . . . . . . .P0524 Adawi, A. . . . . . . . . . . . . . . . . . . . . P1749, P1759 Ader, F. . . . . . . . . . . . . . . . . . . . . . P1295, P1312 Adesokan, A. . . . . . . . . . . . . . . . . . P1189, P1231 Adibpour, N. . . . . . . . . . . . . . . . . . . . . . . .P0674 Adiloglu, A. . . . . . . . . . . . . . . . . . . . . . . . eP605 Aditama, T.Y.. . . . . . . . . . . . . . . . . . . . . . P0464 Adkin, R. . . . . . . . . . . . . . . . . . . . . . . . . .eP452 Adler, A. . . O008, O142, P0231, P1098, P1172, P1656 Adler-Moore, J. . . . . . . . . . . . . . . . . . . . . .P1699 Adomakoh, E. . . . . . . . . . . . . . . . . . . . . . P0839 Adriaenssens, N. . . . . . . . . . . . . . . . O041, P0375 Adriance, S.M. . . . . . . . . . . . . . . . . . . . . . eP476 Adrie, C. . . . . . . . . . . . . . . . . . . . . . . . . . . O232 Aebischer, T.. . . . . . . . . . . . . . . . . . . . . . P0643 Afanasev, M. . . . . . . . . . . . . . . . . . . . . . . eP466 Afanasyev, B. . . . . . . . . . . . . . . . . .P0048, P1317 Affolter, M. . . . . . . . . . . . . . . . . . . . . . . . . P1751 Afzal, H. . . . . . . . . . . . . . . . . . . . . . . . . . . O170 Agababyan, H. . . . . . . . . . . . . . . . . . . . . . P0390 Agafonov, A. . . . . . . . . . . . . . . . . . . . . . . . P0114 Agard, C. . . . . . . . . . . . . . . . . . . . . . . . . .eP112 Agarwal, V.. . . . . . . . . . . . . . . . . . . . . . . .P0654 Agerso, Y. . . . . . . . . . . . . . . . . . . . eP334, P1465 Aghakhani, A. . . . . . . . . . . . . . . . . . . . . . .P1833 Agmon, V. . . . . . . . . . . . . . . . .O032, O179, P1488 Agnoletti, F. . . . . . . . . . . . . . . . . . . . . . . .P0793 Agodi, A. . . . . . . . . . . . . . . . . . . . .P0547, P1000 Agorastos, T. . . . . . . . . . . . . . . . . . . . . . . P1769 Agrafioti, K. . . . . . . . . . . . . . . . . . . . . . . . O205 Agrappi, C. . . . . . . . . . . . . . . . . . . . . . . . P0887 Agrifoglio, A. . . . . . . . . . . . . . . . . . . . . . . P1695 Aguadé, S. . . . . . . . . . . . . . . . . . . . . . . . .eP127 Aguado Garcia, J.M. . . . . . . . . . . . . . . . . . .SY260 Aguado, J. . . . . . . . . . . . . . . eP352, eP356, O214, P0770, P1321, P1486 Agudo, R.. . . . . . . . . . . . . . . . . . . . . . . . P0569 Aguero, F. . . . . . . . . . . . . . . . . . . . . . . . . P1880 Agüero, R. . . . . . . . . . . . . . . . . . . . . . . . .P0972 Aguiar, S. . . . . . . . . . . . . . . . eP154, eP158, P1214 Aguilar, E. . . . . . . . . . . . . . . . . . . . . . . . . P0398 Aguilar, M. . . . . . . . . . . . . . . . . . . . . . . . .P1326 Aguilar-Guisado, M. . . . . . . . . . . . . . eP213, SY280 Aguilera, E. . . . . . . . . . . . . . . . . . . . . . . . P0102 Aguiló, J. . . . . . . . . . . . . . . . . . . . . . . . . P0028 Agulla Budiño, J.A. . . . . . . . . . . . . . . . . . . .eP155 Agustiningsih, A. . . . . . . . . . . . . . . . . . . . .P0457 Agut, H. . . . . . . . . . . . . . . . . . . . . . . . . . P1309 Agyekum, A. . . . . . . . . . . . . . . . . . . . . . . P1012 Agyeman, P. . . . . . . . . . . . . . . . . . . . . . . P0094 Ahlen, C. . . . . . . . . . . . . . . . . . . . . . . . . .P1359 Ahmad, A. . . . . . . . . . . . . . . . . . . . . . . . . O256 Ahmad, S. . . . . . . . . . . . . . eP248, eP249, P0906 Ahman, J. . . . . . . . . . . . . . P0283, P0279, P0280, P0281, P0282, P0285 Ahmed, B. . . . . . . . . . . . . . . . . . . P0242, P0698 Ahmed, D. . . . . . . . . . . . . . . . . . . . . . . . P0850 Ahmed, E. . . . . . . . . . . . . . . . . . . . . . . . .P1947 Ahmed, E.M.. . . . . . . . . . . . . . . . . . . . . . .P0019 Ahmed, N. . . . . . . . . . . . . . . . . . . . . . . . eP200 Ahn, J. . . . . . . . . . . . . . . . . . . . . . . . . . . P1371 Ahn, M.Y. . . . . . . . . . . . . . . . . . . . . . . . . . P1375 Aho, S. . . . . . . . . . . . . . . . . . . . . . . . . . . .O199 Ahren, C. . . . . . . . . . . . . . . . . . . . .eP529, eP534 Aichinger, G. . . . . . . . . . . . . . . . . . . . . . . .eP159 Ainoda, Y. . . . . . . . . . eP045, P0085, P0521, P1792 Aínsa, J.A. . . . . . . . . . . . . . . . . . . . . . . . P0920 Aires de Sousa, M. . . . . . . . . . . . . . . . . . . . .O173 Aissa, S. . . . . . . . . . . . . . . . . . . . . . . . . P0420 Ajdler-Schäffler, E. . . . . . . . . . . . . . . . . . . . .O178 Ak, O. . . . . . . . . . . . . . . . . P0408, P0999, P1606 Akalan Kuyumcu, C.. . . . . . . . . . . . . . . . . .eP581 Akalin, T. . . . . . . . . . . . . . . . . . . . . . . . . P0084 Akay, D. . . . . . . . . . . . . . . . . . . . . . . . . . P1606 Akay, O.M. . . . . . . . . . . . . . . . . . . . . . . . .P1276 Akbal, U. . . . . . . . . . . . . . . . . . . . . . . . . .P1928 Akbar, A. . . . . . . . . . . . . . . . . . . . . . . . . P0662 Akcay, S.S. . . . . . . . . . . . . . . . . . . . . . . . eP580 Akçelik, M. . . . . . . . . . . . . . . . . . . . . . . . eP303 Akçelik, N. . . . . . . . . . . . . . . . . . . . . . . . eP303 Akdeniz, H. . . . . . . . . . . . . . . . . . . . . . . . P1623 Akduman, D. . . . . . . . . . . . . . . . . . . . . . . P0461 Akengin Ocal, G. . . . . . . . . . . . . . . . . . . . .P0999 Åkerlund, A. . . . . . . . . . . . . . . . . . . . . . . .P0334 Akhalaia, M. . . . . . . . . . . . . . . . . . . . . . . . O086 Akhoon, C. . . . . . . . . . . . . . . . . . . . . . . . P0548 Akiti, T. . . . . . . . . . . . . . . . . . . . . . . . . . .eP368 Akkerboom, V. . . . . . . . . . . . . . . . . . . . . . .O034 Akkoyunlu, Y. . . . . . . . . . . . . . . . . . . . . . P0407 Akkutay, A.Z. . . . . . . . . . . . . . . . . . . . . . P0450 Akova, M. . . . . . . . . . . . . . . eP336, P1192, P1631 Aksaray, S. . . . . . . . . . . . . . . . . . . . . . . . P0220 Aksenova, E.I. . . . . . . . . . . . . . . . . . . . . . P0611 Aksoy, M. . . . . . . . . . . . . . . P0366, P0367, P0368 Aksu, B. . . . . . . . . . . . . . . . . . . . . . . . . . P0902 Aksu, H.S.Z. . . . . . . . . . . . . . . . . . . . . . . P0069 Aksu, N. . . . . . . . . . . . . . . . . . . . . . . . . . P1006 Aktas, F. . . . . . . . . . . . . . . . . . . . . . . . . . eP359 Aktas, Z. . . . . . . . . . . . . . . . . . . . P0223, P0227 Akter, N. . . . . . . . . . . . . . . . . . . . . . . . . P0850 Akulenko, R.. . . . . . . . . . . . . . . . . . . . . . .P1539 Akyar, I. . . . . . . . . . . . . . . . . P0287, eP479, O059 Al Aidy, S. . . . . . . . . . . . . . . . . . . . . . . . . P0410 Al Ameri, R. . . . . . . . . . . . . . . . . . . . . . . . P0463 Al Ghazal, H. . . . . . . . . . . . . . . . . . . . . . . P0965 Al Hassar, O. . . . . . . . . . . . . . . . . . . . . . . .P1834 Al Helal, H. . . . . . . . . . . . . . . . . . . . . . . . .P0912 Al Johani, S. . . . . . . . . . . . . . . . . . .P0912, P0965 Al Kafari, E. . . . . . . . . . . . . . . . . . . . . . . .P0466 Al Musawi, T. . . . . . . . . . . . . . . . . . . . . . . P0470 Al Mutairy, J. . . . . . . . . . . . . . . . . . . . . . .P0466 Al Naiemi, N. . . . . . . . . . . . . . . . . . P0549, P1216 Al Najdi, S. . . . . . . . . . . . . . . . . . . . . . . . .P1597 Al- Obaidi, K. . . . . . . . . . . . . . . . . . . . . . . P1045 Al Qudairy, H. . . . . . . . . . . . . . . . . . . . . . P0466 Al Ragi, N. . . . . . . . . . . . . . . . . . . . . . . . P0466 Al Shahrani, D.A. . . . . . . . . . . . . . . . . . . . P0466 Al Shehri, M. . . . . . . . . . . . . . . . . . . . . . . P0466 Alabi, A.. . . . . . . . . . . . . . . . . . . . . .O171, P1539 Alabi, A.S. . . . . . . . . . . . . . . . . . . . . . . . . .O022 Al-Abri, S. . . . . . . . . . . . . . . eP015, P1050, P1148 Alacam, S. . . . . . . . . . . . . . . . . . . . . . . . P1006 Al-Ahmad, A. . . . . . . . . . . . . . . . . . . . . . . P0386 Alamgir, A.S.M. . . . . . . . . . . . . . . . . . . . . .P0242 Alamo, L. . . . . . . . . . . . . . . . . . . . . . . . . .eP314 Álamo-Martínez, J.M. . . . . . . . . . . . . . . . . .P1306 AlAmri, A. . . . . . . . . . . . . . . . . . . . . . . . . P1904 Alamri, W.M. . . . . . . . . . . . . . . . . . . . . . . .P0924 Alanio, A. . . . . . . . . . . . . . . . .eP375, O218, P0024 Alarcón, T. . . . . . . . . . . . . . . . . . . . P0137, P0872 Alastruey-Izquierdo, A. . . . . . . . . . . . . . . . .eP392 Alavi Darazam, I. . . . . . . . . . . . . . . . . . . . .P1704 Alavian, S.M. . . . . . . . . . . . . . . . . . . . . . . .O095 Alawy, H. . . . . . . . . . . . . . . . . . . . . . . . . .P0250 Albaadani, A.M. . . . . . . . . . . . . . . . . . . . . .eP524 Albaraak, A.M. . . . . . . . . . . . . . . . . . . . . . eP206 24th ECCMID / Barcelona Final Programme 251 Exhibition NameNumber General Information NameNumber Chairs, Speakers & Authors List of Speakers & Authors List of Speakers & Authors NameNumber NameNumber NameNumber Albarghy, H. . . . . . . . . . . . . . . . . . . . . . . .P0410 Albarouni, A.S. . . . . . . . . . . . . . . . . . . . . . P0924 Albarrag, A. . . . . . . . . . . . . . . . . . . . . . . .P1395 Albayrak, A. . . . . . . . . . . . . . . . . . . . . . . P0440 Alberti, S. . . . . . . . . . . . . . . . . . . . . . . . . P0175 Albertini, R. . . . . . . . . . . . . . . . . . . . . . . .P1289 Albines Fiestas, Z.S. . . . . . . . . . . . . . . . . . .P1258 Albini, L. . . . . . . . . . . . . . . . . . . . . . . . . .P1882 Albonico, G. . . . . . . . . . . . . . . . . . . . . . . .P1289 Albornoz, E. . . . . . . . . . . . . . . . . . . . . . . . eP317 Albouy-Llaty, M. . . . . . . . . . . . . . . . . . . . .eP043 Albrecht, C. . . . . . . . . . . . . . . . . . . . . . . . P0890 Alcaide, F. . . . . . . . . . . . . . . . . . . . P0908, P0931 Alcaide, M. . . . . . . . . . . . . . . . . . . . . . . . .eP572 Alcala, L. . . . . . . . . . . P0741, eP474, P1081, eP105 Alcazar-Fuoli, L. . . . . . . . . . . . . . . . . . . . P0005a Alcoba-Flórez, J. . . . . . . . . . . . . . . .eP560, P1578 Alcocer, I. . . . . . . . . . . . . . . . . . . . . . . . . P1111 Alcolea, N. . . . . . . . . . . . . . . . . . . . . . . . .P1886 Aldalbhi, S.K. . . . . . . . . . . . . . . . . . . . . . eP206 Aldarweesh, M. . . . . . . . . . . . . . . . . . . . . P0470 Aldeguer Manté, X. . . . . . . . . . . . . . . . . . . eP496 Al-Den, A. . . . . . . . . . . . . . . . . . . . . . . . . eP070 Aldigs, E.K. . . . . . . . . . . . . . . . . . . . . . . . .O049 Aldini, R. . . . . . . . . . . . . . . . . . . . . . . . . .P0120 Aldins, P. . . . . . . . . . . . . . . . . . . . . . . . . .P0501 Aldridge, C. . . . . . . . . . . . . . . . . . . eP543, P0796 Alegre, M.D. . . . . . . . . . . . . . . . . . . . . . . .P0419 Alejandre, C. . . . . . . . . . . . . . . . . . . . . . . P0317 Alejandria, M.M. . . . . . . . . . . . . . . . . . . . . eP235 Alejo Cancho, I. . . . . . . . . . . . . . . . . . . . . .P1386 Alejo, I. . . . . . . . . . . . . . . . . . . . . eP098, P1844 Alekhin, A. . . . . . . . . . . . . . . . . . . . . . . . .P1494 Alekseev, A. . . . . . . . . . . . . . . . . . . . . . . .eP205 Aleksiejczuk, P. . . . . . . . . . . . . . . . . . . . . .eP078 Alem, N. . . . . . . . . . . . . . . . . . . . . . . . . . eP391 Aleo, A. . . . . . . . . . . . . . . . . . . . . . . . . . .P1633 Alex, L. . . . . . . . . . . . . . . . . . . . . . . . . . . P1735 Alexandrova, I.A. . . . . . . . . . . . . . . . . . . . P0605 Alfageme, I. . . . . . . . . . . . . . . . . . . . . . . .eP150 Alfahad, W.A. . . . . . . . . . . . . . . . . . . . . . . eP206 Alfahadl, W.A. . . . . . . . . . . . . . . . . . . . . . .eP524 Alfandari, S. . . . . . . . . . . . . . . . . . .P0376, P0417 Alghamdi, N. . . . . . . . . . . . . . . . . . . . . . . eP523 Alghoribi, M. . . . . . . . . . . . . . . . . . . . . . . .P0168 Al-Ghusein, H. . . . . . . . . . . . . . . . . . . . . . .O238 Alhetheel, A. . . . . . . . . . . . . . . . . . . . . . . P1395 Ali Amin, M. . . . . . . . . . . . . . . . . . . . . . . P0993 Ali Rimi, N. . . . . . . . . . . . . . . . . . . . . . . . P0445 Ali, D. . . . . . . . . . . . . . . . . . . . . . . . . . . .P0818 Ali, M. . . . . . . . . . . . . . . . . . . . . . . . . . . .P1377 Ali, S. . . . . . . . . . . . . . . . . . . . . . . . . . . .P1069 Alia, E. . . . . . . . . . . . . . . . . . . . . . . . . . . eP500 Al-Ibrahim, M.. . . . . . . . . . . . . . . . . . . . . P0458 Alier, A. . . . . . . . . . . . . . . . . . . . . eP229, P0384 Alikhani, M. . . . . . . . . . . . . . . . . . . . . . . .P0877 Aliouat, E.M. . . . . . . . . . . . . . . . . . . . . . . . O084 Aliyu, S.H. . . . . . . . . . . . . . . . . . . . eP366, O208 Al-Jardani, A. . . . . . . . . . . . . eP015, P1050, P1148 Aljubran, S. . . . . . . . . . . . . . . . . . . . . . . . eP373 Al-Jubury, A. . . . . . . . . . . . . . . . . . . . . . . P0718 Alkafash, D. . . . . . . . . . . . . . . . . . . . . . . P1942 Alkan, A. . . . . . . . . . .P0366, P0365, P0367, P0368 Alkhatib, G. . . . . . . . . . . . . . . . . . . . . . . . .O024 AlKhizzi, N. . . . . . . . . . . . . . . . . . . . . . . . eP373 Alkhuraish, N. . . . . . . . . . . . . . . . . . . . . . eP373 Allain-Launay, E. . . . . . . . . . . . . . . . . . . . .P0277 Allajbeu, K. . . . . . . . . . . . . . . . . . . . . . . . eP307 Allali, M. . . . . . . . . . . . . . . . . . . . . . . . . . P1302 Allaouchiche, B. . . . . . . . . . . . . . . . . . . . . P0031 Allard, M. . . . . . . . . . . . . . . . . . . . . . . . . .eP143 Al-Lawati, B. . . . . . . . . . . . . . . . . . . . . . . . P1221 Allegranzi, B. . . . . . . . . . . . . . . . . . . . . . .SY128 Allen, A. . . . . . . . . . . . . . . . . . . . . . . . . . .O067 Allen, M. . . . . . . . . . . . . . . . . . . . . . . . . . eP412 Aller, A.I. . . . . . . . . . . . . . . . . . . . . . . . . . P1517 Allerberger, F. . . . . . . . eP266, P0716, P0795, P1541 Allerheiligen, V. . . . . . . . . . . . . . . . . . . . . .P0919 Allers, E. . . . . . . . . . . . . . . . . . . . . . . . . P0539 Allice, T. . . . . . . . . . . . . . . . . . . . . . O164, P1760 Allignol, A. . . . . . . . . . . . . . . . . . . . . . . . . O192 Allison, D. . . . . . . . . . . . . . . . . . . . eP543, P0796 Allizond, V. . . . . . . . . . . . . . . . . . . . . . . . .P0133 Almaghrabi, R. . . . . . . . . . . . . . . . .P1199, P1780 Al-Mahallawy, H. . . . . . . . . . . . . . . . . . . . .P1281 AlMazrou, A. . . . . . . . . . . . . . . . . . . . . . . .P0410 Almeida da Silva, P.E. . . . . . . . . . . . . . . . . .P0925 Almeida, A. . . . . . . . . . . . . . . . . . . . . . . . P1889 Almeida, J. . . . . . . . . . . . . . . P1007, P1022, P1459 Almela, M. . . . .eP098, eP104, eP123, eP356, P0506 Almirall, J. . . . . . . . . . . . . . . . . . . . . . . . .P0621 Almirante, B. . . . . . . . . . . . . eP047, eP127, eP352, P0041, P0766, P1486 Almitwazi, A.A. . . . . . . . . . . . . . . . . . . . . eP206 Al-Muharrmi, Z. . . . . . . . . . . . . . . . . . . . . . P1221 Almuhayawi, M. . . . . . . . . . . . . . . . . . O187, O190 Alo, M. . . . . . . . . . . . . . . . . . . . . . . . . . . eP579 Alonso Castañeda, B. . . . . . . . . . . . . . . . . .P0701 Alonso, C.A. . . . . . . . . . . . . . . . . . . . . . . .P0236 Alonso, I. . . . . . . . . . . . . . . . . . . . . . . . . . O122 Alonso, M. . . . . . . . . . . . . . . eP544, O254, P1786 Alonso, N. . . . . . . . . . . . . . . . . . . . . . . . .P1637 Alonso, P.L. . . . . . . . . . . . . . . . . . . . . . . . P1261 Alonso, S. . . . . . . . . . . . . . . . . . . . . . . . . eP597 Alp Cavus, S. . . . . . . . . . . . . . . . . . . . . . . P0477 Alp Mese, E. . . . . . . . . . . . . eP040, eP050, eP057, P0080, P1187, P1551, P1622 Alp, E. . . . . . . . . . . . . . . . . .P1082, P1200, P1267 Alparslan Gönültas, M. . . . . . . . . . . . . . . . P1956 Alpay, N. . . . . . . . . . . . . . . . . . . . . . . . . .P1840 Alpay, Y. . . . . . . . . . . . . . . . . . . . . . . . . . P1831 Alsaeed, A. . . . . . . . . . . . . . . . . . . . . . . . eP176 ALShamrani, M. . . . . . . . . . . . . . . . . . . . . P1904 AlSobhi, A. . . . . . . . . . . . . . . . . . . . . . . . .P1904 Al-Sweih, N. . . . . . . . . . . . . . . . . . . . . . . .P1222 Altamirano, J. . . . . . . . . . . . . . . . . . . . . . . O241 Alten, B. . . . . . . . . . . . . . . . . . . . . . . . . . P0450 Altermatt, M. . . . . . . . . . . . . . . . . . . . . . . P0275 AlThaqafi, A. . . . . . . . . . . . . . . . . . . . . . . .P1904 Altindag, F. . . . . . . . . . . . . . . . . . . . . . . . P0407 Altinkanat Gelmez, G. . . . . . . . . . . . . . . . . .P1182 Altukhov, I. . . . . . . . . . . . . . . . . . . . . . . . P0976 Altun, B. . . . . . . . . . . . . . . . . . . . . . . . . .P1192 Altun, D. . . . . . . . . . . . . . . . . . . . . . . . . .P1551 Altun, O. . . . . . . . . . . . . . . . . . . . . . . O187, O190 Altwegg, M. . . . . . . . . . . . . . . . . . . eP573, P1751 Alutis, M. . . . . . . . . . . . . . . . . . . . . . . . . .P0119 Alvar, J.. . . . . . . . . . . . . . . . . . . . . . . . . .SY200 Álvarez Domínguez, C. . . . . . . . . . . . . . . . .P0187 Alvarez Figueroa, M. . . . . . . . . . . . . . . . . . P0911 Alvarez Lerma, F. . . . . . P0576, P1709, P1727, P1776 Alvarez Marin, R. . . . . . . . . . . . . . . . . . . . . P0177 Alvarez, E. . . . . . . . . . . . . . . . . . . . . . . . .P1380 Álvarez, H. . . . . . . . . . . . . . . . . . . . . O021, O023 Alvarez, J.M. . . . . . . . . . . . . . . . . . . . . . . P1361 Alvarez, M. . . . . . . . . . . . . . . . . . . P1243, eP471 Alvarez, R. . . . . . . . . . . . . . . . . . . . . eP117, O122 Álvarez-Álvarez, M.I. . . . . . . . . . . . . . . . . . P0045 Alvarez-Argüelles, M. . . . . . . . . . . . . . . . . . P1767 Álvarez-Díaz, H. . . . . . . . . . . . . . . . P0950, P0957 Álvarez-Fernández, M. . . . . . . . . . . . . . . . P0045 Álvarez-Pérez, S.. . . . . . . . . . . . . . . . . . . .eP245 Alves Nunes Mario, D.. . . . . . . . . . . . . . . . .P0023 Alves, A. . . . . . . . . . . . . . . . . . . . . . . . . .P1092 Alves, M. . . . . . . . . . . . . . . . . . . . . . . . . .P1164 Alves, S. . . . . . . . . . . . . . . eP286, P0003, P0830 Alyabieva, N. . . . . . . . . . . . . . . . . . . . . . . .O206 Alzagawy, S.M. . . . . . . . . . . . . . . . . . . . . .P0707 Amaral, M. . . . . . . . . . . . . . . . . . . . . . . . .P1203 Amaro, J.. . . . . . . . . . . . . . . . . . . . . . . . .P1362 Amarsy, R. . . . . . . . . . . . . . . . . . . . . . . . . O088 Amarsy-Guerle, R. . . . . . . . . . . . . . . . . . . . O183 Amarti, A. . . . . . . . . . . . . . . . . . . . . . . . . P0873 Amato, G. . . . . . . . . . . . . . . . . . . . . . . . . eP212 Amatya, P. . . . . . . . . . . . . . . . . . . . . . . . . P1218 Ambert-Balay, K. . . . . . . . . . . . . . . . . . . . .P1394 Ambler, J. . . . . . . . . . . . . . . . . . . . . . . . . P1588 Ambretti, S. . . . . . . . . . . . . . . . . . .eP325, P1265 Ambrose, P. . . . . . . . . . . . . . . . . . . . . . . . P1743 Amendola, A. . . . . . . . . . . . . . . . . . . . . . . P1412 Ameri, L. . . . . . . . . . . . . . . . . . . . . . . . . P0422 Amir, J. . . . . . . . . . . . . . . . . . . . . . . . . . .P1861 Amit, S. . . . . . . . . . . . . . . . . . . . . . . . . . .P0104 Ammari, H. . . . . . . . . . . . . . . . . . . . . . . . P1238 Ammari, L.. . . . . . . . . . . . . . . . . . . . . . . P0420 Amorim, J. . . . . . . . . . . . . . . . . . . . . . . . . P1021 Amyes, S. . . . . . . . . . . . . . . . . . . .P0230, P1045 Anagnostopoulos, A. . . . . . . . . . . . . . O178, P1913 Ananda-Rajah, M. . . . . . . . . . . . . . . . . . . . eP367 Anantharajah, A. . . . . . . . . . . . . . . . . . . . . P0174 Ananyina, Y.U.V. . . . . . . . . . . . . . . . . . . . . P0611 Anas, A.A. . . . . . . . . . . . . . . . . . . . . . . . . P0145 Anastasiou, E.D. . . . . . . . . . . . . . . . . . . . .P1655 Anastassiou, E. . eP311, eP357, eP607, eP608, P1788 Anastassiou, E.D. . . . . . . . . . . . . . . . . . . . P0208 Anders, A. . . . . . . . . . . . . . . . . . . . P1037, P1176 Andersen, C. . . . . . . . . . . . . . . . . . . . . . . eP195 Andersen, C.O. . . . . . . . . . . . . . . . . . . . . . P0582 Andersen, J.M. . . . . . . . . . . . . . . . . . . . . .P0129 Andersen, L. . . . . . . . . . . . . . . . . . eP280, P0718 Andersen, L.P. . . . . . . . . . . . . . . . . . . . . .EW021 Andersen, N.S. . . . . . . . . . . . . . . . . . . . . .eP081 Andersen, P.S. . . . . . . . . . . . . . . . . . . . . . . O120 Anderson, A.S. . . . . . . . . . . . . . . . . eP134, eP146 Anderson, M. . . . . . . . . . . . . . . . . . . . . . .eP291 Anderson, R. . . . . . . . . . . . . . . . . . . . . . . eP486 Andersson, M. . . . . . . . . . . . . . . . . . . . . . .O229 Andersson, O. . . . . . . . . . . . . . . . . . . . . . .P1053 Andersson, P.O. . . . . . . . . . . . . . . . . . . . . P0429 Andersson, S. . . . . . . . . . . . . . . . . . . . . . P0538 Andersson, U. . . . . . . . . . . . . . . . . . . . . . P0209 Andes, D.. . . . . . . . . . . . . . . . . . . . . . . . . P1735 Andrade, L. . . . . . . . . . . . . . . . . . . . . . . . P0151 Andrade, L.N. . . . . . . . . . . . . . . . . . P1025, P1132 Andrade, M. . . . . . . . . . . . . . . . . . . . . . . . O073 Andre, C. . . . . . . . . . . . . . . . . . . . . . . . . .P1139 Andreis, S. . . . . . . . . . . . . . . . . . . . O166, P1895 Andrejak, C. . . . . . . . . . . . . . . . . . P0896, P0952 Andremont, A. . . . . . . P0248, P0348, P0804, P1217 Andrén, O. . . . . . . . . . . . . . . . . . . . . . . . .P0188 Andreoletti, L. . . . . . . . . . . . . . . . . . O162, P0479 Andreoni, F. . . . . . . . . . . . . . . . . . . O064, P0201 Andreoni, S. . . . . . . . . . . . . . . . . . . . . . . .eP465 Andrés, M. . . . . . . . . eP552, eP553, P0419, P0608 Andreu, A. . . . . . . . . . . . . . . . . . . .P0975, P1064 Andreu, M. . . . . . . . . . . . . . . . . . . . . . . . . O101 Andrianaki, A. . . . . . . . . . . . . . . . . P0666, P1284 252 24th ECCMID / Barcelona Final Programme NameNumber Anesi, A. . . . . . . . . . . . . . . . eP265, P0722, P1797 Ang, B. . . . . . . . . . . . . . . . . . . . . . . . . . P0558 Ang, B.S. . . . . . . . . . . . . . . . . . . . . . . . . .P1483 Angarano, G. . . . . . . . . . . . . . . . . . . . . . . eP124 Angebault, C. . . . . . . . . . . . . . . . . . . . . . P0043 Ängeby, K. . . . . . . . . . . . . . . . . . . . . . . . P0956 Angelini, A. . . . . . . . . . . . . . . . . . . . . . . . P0618 Angelone, A. . . . . . . . . . . . . . . . . . . . . . . . O073 Angelov, I. . . . . . . . . . . . . . . . . . . . . . . . .P0318 Anger, K. . . . . . . . . . . . . . . . . . . . . . . . . .P1904 Angoulevant, A. . . . . . . . . . . . . . . . . . . . . P0011 Anguita-Santos, F. . . . . . . . . . . . . . . . . . . P0968 Anibarro, L. . . . . . . . . . . . . . . . . . . . . . . P0949 Anica Hadji-Petrusheva Jankijevikj, A. . . . . . P0395 Anil, M. . . . . . . . . . . . . . . . . . . . . . . . . . .eP401 Anish, C. . . . . . . . . . . . . . . . . . . . . . . . . .P1263 Anjum, M. . . . . . . . . . . . . . . . . . . . P1634, P1643 Annaert, P. . . . . . . . . . . . . . . . . . . . . . . . .P1696 Annerstedt, C. . . . . . . . . . . . . . . . . P0212, P0213 Anquetil, D. . . . . . . . . . . . . . . . . . . . . . . . O255 Ansgar-Bruun, J. . . . . . . . . . . . . . . . . . . . .eP136 Anson, L.W. . . . . . . . . . . . . .eP087, P0535, P0852 Anstey, J. . . . . . . . . . . . . . . . . . . . . . . . . P1319 Antachopoulos, C. . . . . . . . . . . . . . . . . . . .P1230 Anthony, R. . . . . . . . . . O039, O086, P0884, P0971 Anthony, R.M.. . . . . . . . . . . . . . . . . . . . . . O089 Anthonypillai, J. . . . . . . . . . . . . . . . . . . . . O170 Antinori, S.. . . . . . . . . . . . . . . . . . . . . . . P0683 Antochevis, L.C. . . . . . . . . . . . . . . . . . . . . O242 Antoine, M. . . . . . . . . . . . . . . . . . . . . . . . P1319 Antón, A. . . . . . . . . . . . . . . . . . . . . . . . . . P1271 Antonelli, G. . . . . . . . . . . . . . P0160, O026, P1423 Antoniadou, A. . . . . . . . . . . . . . . . . . . . . .P0557 Antonio, M. . . . . . . . . . . . . . . . . . . . . . . . P0725 Antoniou, M. . . . . . . . . . . . . . . . . . . . . . . P0666 Antonova, E. . . . . . . . . . . . . . . . . . . . . . . P1244 Antunes, F. . . . . . . . . . . . . . . . . . . . . . . . eP312 Antunes, P. . . . . . . . . . eP285, O139, P0846, P1013 Anuka, E.. . . . . . . . . . . . . . . . . . . . O179, P1488 Aoki, K. . . . . . . . . . . . . . . . . . . . . . . . . . .P0163 Aouam, A. . . . . . . . . . . . . . . . . . . . . . . . .P1832 Aoyagi, T. . . . . eP038, eP161, P0163, P0992, P1039 Apagyi, K. . . . . . . . . . . . . . . . . . . . . . . . . O038 Apfalter, P. . . . . . . . . . . . . . . . . . . . . . . . .eP592 Apostolakis, I. . . . . . . . . . . . . . . . . . . . . . eP613 Appel, B. . . . . . . . . . . . . . . . . . . . . . . . . .P1637 Aquino, F. . . . . . . . . . . . . . . . . . . . . . . . . P1360 Aquino, M.Z. . . . . . . . . . . . . . . . . . . . . . . .eP388 Ara, K. . . . . . . . . . . . . . . . . . . . . . . . . . . P0242 Arakawa, H. . . . . . . . . . . . . . . . . . . P0138, P0247 Arakere, G. . . . . . . . . . . . . . . . . . . . . . . . .P0192 Arama, V.. . . . . . . . . P0393, P0696, P1884, P1941 Aranzábal, L. . . . . . . . . . . . . . . . . . . . . . .eP597 Araoka, H. . . . . . . . . . . . . . . . . . . . P1268, P1270 Aras, F. . . . . . . . . . . . . . . . . . . . . . . . . . P0607 Araujo García, Z. . . . . . . . . . . . . . . . . . . . .P0970 Araujo Lima, B. . . . . . . . . . . . . . . . . . . . . .P0323 Araujo, B. . . . . . . . . . . . . . . . . . . . . . . . . P1860 Araújo, M.R.E. . . . . . . . . . . . . . . . . . . . . . .P1738 Araujo, R. . . . . . . . . . . . . . . . . . . . . . . . . eP502 Araújo, S. . . . . . . . . . . . . . . . . . . . P1092, P1164 Aravena Urrutia, M. . . . . . . . . . . . . . . . . . . P1872 Arcangeletti, M.C. . . . . . . . . . eP478, eP480, O184, O267, P0669, P1429, P1430, eP477 Arce-Fonseca, M. . . . . . . . . . . . . . . . . . . . eP138 Arch, O. . . . . . . . . . . . . . . . . . . . . .eP039, eP053 Archambaud, M. . . . . . . . . . . . . . . .P1843, P1558 Archeny, D. . . . . . . . . . . . . . . . . . . . . . . . . O075 Archimbaud, C. . . . . . . . . . . . . . . . . . . . . P0469 Arcilla, C. . . . . . . . . . . . . . . . . . . . . . . . . .P1248 Arcilla, M.S. . . . . . . . . . . . . . . . . . . . . . . P1021a Arcson, Á. . . . . . . . . . . . . . . . . . . . . . . . .eP482 Arda, B. . . . . . . . . . . . . . . . . . . . . . . . . . .P1873 Ardanuy Tisaire, C. . . . . . . . . . . . . . . P1517, P1520 Ardanuy, C. . . . . . . . . eP149, P0980, P1035, P1338 Areal, J. . . . . . . . . . . . . . . . . . . . . . . . . . P0573 Arebestani, M. . . . . . . . . . . . . . . . . . . . . . P0877 Arena, F. . . . . . . . . . . . . . . . . . . . . O263, P0579 Arend, L. . . . . . . . . . . . . . . . . . . . . .eP610, O160 Arendrup, M. . . . . . . . . . . . . . . . . . .eP242, O083 Arendrup, M.C. . . . . . . eP252, eP389, IS020, P0073 Arends, J. . . . . . . . . . . . . . . . . . . . . . . . . .O091 Arends, J.E. . . . . . . . . . . . . . . . . . . . . . . . IS011 Arends, J.P. . . . . . . . . . . . . . . . . . . . . . . . .O069 Arents, N.L.A. . . . . . . . . . . . . . . . . . . . . . .P0341 Argaud, L. . . . . . . . . . . . . . . . . . . . . . . . .eP073 Argentero, P.A. . . . . . . . . . . . . . . . . . . . . . P0556 Argiropoulou, A. . . . . . . . . . . . . . . . . . . . . P0610 Argyropoulou, A. . . . . . . . . . . . . . . .P0081, P1186 Arhin, F.F. . . . . . . . . . . eP173, eP174, eP416, eP417 Arias, A. . . . . . . . . . . . . . . . . . . . . . . . . . P1640 Arias, S. . . . . . . . . . . . . . . . . . . . . . . . . . P0575 Arib, S. . . . . . . . . . . . . . . . . . . . . . . . . . .eP559 Arican, R.k. . . . . . . . . . . . . . . . . . . . . . . . P1549 Arientova, S. . . . . . . . . . . . . . . . . . eP548, P1340 Arinto-Garcia, R. . . . . . . . . . . . . . . . . . . . P0593 Arioli, S. . . . . . . . . . . . . . . . . . . . . . . . . . . O061 Arismendi Sosa, A. . . . . . . . . . . . . . . . . . . P0137 Aristizabal, F. . . . . . . . . . . . . . . . . . . . . . .P0237 Aritonovic Pribakovic, J. . . . . . . . . . .P0687, P0688 Ariza, J. . . . . . eP039, eP053, P0095, P1454, P1457 Ariza-Heredia, E. . . . . . . . . . . . . . . . . . . . . O106 Arlet, G.. . . . . . . . . . . . . . . . . . . . . . . . . .P0351 Armaganidis, A. . . . . . . . . . . . . . . . . . . . . P0216 Armalyte, J. . . . . . . . . . . . . . . . . . . . . . . . P1141 Arman, D. . . . . . . . . . . . . . . . . . . . . . . . . eP359 Armand-Lefevre, L. . . . . . . . . . . . . . . . . . . P1217 Armanini, D. . . . . . . . . . . . . . . . . . . . . . . P0009 Armannsdottir, B. . . . . . . . . . . . . . . . . . . . P1272 Armero, Y. . . . . . . . . . . . . . . . . . . .eP123, P0088 Armiñanzas, C. . . . . . . . . . . . . . . . P1800, P1899 Armitano, S. . . . . . . . . . . . . . . . . . . . . . . P0562 Armstead, J. . . . . . . . . . . . . . . . . . . . . . . .O236 Arnaiz Garcia, A. . . . . . . . . . . . . . . . . . . . .P1258 Arnalich, F. . . . . . . . . . . . . . . . . . . . . . . . EW029 Arnan, M. . . . . . . . . . . . . . . . . . . . . . . . .P0050 Arnet, I.. . . . . . . . . . . . . . . . . . . . . . . . . .P0275 Arnold, C. . . . . . . . . . . . . . . . . . . . . O252, P0918 Arnold, T. . . . . . . . . . . . . . . . . . . . . . . . . .P1406 Aronoff, D.M. . . . . . . . . . . . . . O097, P0774, P0785 Arpin, C. . . . . . . . . . . . . . . . . . . . . . . . . . P1142 Arroyo Fajardo, A. . . . . . . . . . . . . . . P0697, P0867 Arroyo, A. . . . . . . . . . . . . . . . . . . . . . . . . P0695 Arroyo, J.L. . . . . . . . . . . . . . . . . . . . . . . . P0972 Arruda, P. . . . . . . . . . . . . . . . . . . . . eP610, O160 Arsac, M. . . . . . . . . . . . . . . . . . . . eP460, P0496 Arshad, S. . . . . . . . . . . . . . . . . . . eP429, eP589 Arslan, A. . . . . . . . . . . . . . . . . . . . . . . . . P1337 Arslan, F. . . . . . . . . . . . . . . . . . . . . . . . . .P1840 Arslan, H. . . . . . . . . . . . . . . P0067, P1365, P1366 Arslan, K. . . . . . . . . . . . . . . eP605, P1956, P1957 Artacho, M.J. . . . . . . . . . . . . . . . . . . . . . . eP117 Arter Williams, J. . . . . . . . . . . . . . . . . . . . .P1422 Arthaud, C. . . . . . . . . . . . . . . . . . . . . . . . eP460 Artini, M. . . . . . . . . . . . . . . . . . . . . . . . . .eP289 Artom, F. . . . . . . . . . . . . . . . . . . . . . . . . P0039 Artuk, C. . . . . . . . . . . . . . . . . . . . . . . . . .P0702 Arvand, M. . . . . . . . . . . . . . . . . . . . . . . . P1046 Arvaniti, A.. . . . . . . . . . . . . . . . . . . . . . . .eP282 Arvas, G. . . . . . . . . . . . . . . . . . . . . . . . . P0407 Asadi, L. . . . . . . . . . . . . . . . . . . . . . . . . .eP582 Asaduzzaman, M. . . . . . . . . . . . . . . . . . . P0445 Asahara, M. . . . . . . . . . . . . . . . . . eP020, P0491 Asahata, S. . . . . . . . . . . . . . eP045, P0085, P1792 Asano-Mori, Y.. . . . . . . . . . . . . . . . . . . . . .P1268 Asaoku, H. . . . . . . . . . . . . . . . . . . . . . . . . O239 Aschbacher, R. . . . . . . . . . . . . . . . . . . . . EW001 Ascioglu, S. . . . . . . . . . . . . . . . . . . . . . . EW053 Ascione, T. . . . . . . . . . . . . . . . . . . .eP055, P1455 Asege, L. . . . . . . . . . . . . . . . . . . . . . . . . .P0919 Asehnoune, K. . . . . . . . . . . . . . . . . . . . . .P0100 Asencio, M.A. . . . . . . . . . . . . . . . . . . . . . .P1790 Asensi, M.D. . . . . . . . . . . . . . . . . . . . . . . P0997 Asensio, M.J. . . . . . . . . . . . . . . . . . . . . . .P1695 Ashby, J. . . . . . . . . . . . . . . . . . . . . . . . . eP486 Ashiru-Oredope, D.A. . . . . . . . . . . . . . . . . . eP542 Ashkenazi, S. . . . . . . . . . . . . . . . . . . . . . .P1861 Ashwin, H. . . . . . . . . . . . . . . . . . . . O002, P0852 Ashwin, H.M. . . eP087, P0738, P0753, P0797, P0799 Aslan, A. . . . . . . . . . . . . . . . . . . . . . . . . P0963 Aslan, A.L.P. . . . . . . . . . . . . . . . . . . . . . . .eP126 Aslanghul, E. . . . . . . . . . . . . . . . . . . . . . .P1562 Asli, A. . . . . . . . . . . . . . . . . . . . . . . . . . . P1564 Asner, S. . . . . . . . . . . . . . . . . . . . . . . . . P0468 Aspevall, O. . . . . . . . . . . . . . . . . . . . . . . .P1599 Aspichueta, C. . . . . . . . . . . . . . . . . . . . . . P1525 Aspindzelashvili, R. . . . . . . . . . . . . . . . . . . O086 Aspiroz, C. . . . . . . . . . . . . . . . . . . . . . . . .P1653 Aspöck, H. . . . . . . . . . . . . . . . . . . . . . . . P0692 Assato, P.A. . . . . . . . . . . . . . . . . . . . . . . . P0027 Asseray, N. . . . . . . . . . . . . . eP410, P1452, P1842 Asseva, G. . . . . . . . . . . . . . .P0776, P0794, P1084 Assous, M.V.. . . . . . . . . . . . . O008, P1098, P1172 Astagneau, P. . . . . . . . . . . . .eP022, eP058, P1795 Asticcioli, S. . . . . . . . . . . . . . . . . . . . . . . .P0722 Astolfi, A.. . . . . . . . . . . . . . . . . . . . . . . . . .O071 Astray, J. . . . . . . . . . . . . . . . . . . . . . . . . eP603 Astvad, K.M.T. . . . . . . . . . . . . . . . . . . . . . eP252 Asuquo, E. . . . . . . . . . . . . . . . . . . . . . . . .P0074 Aswani, V. . . . . . . . . . . . . . . . . . . . . . . . .eP162 Atalay Kurkcu, C. . . . . . . . . . . . . . . . . . . . .P1622 Atalay, A. . . . . . . . . . . . . . . . . . . . . . . . . P0080 Atalay, E. . . . . . . . . . . . . . . . eP140, P0671, P0691 Ataman Hatipoglu, C. . . . . . . P1056, eP605, P0459, P1344, P1829, P1956, P1957 Athan, E. . . . . . . . . . . . . . . . . . . . . P0807, P1811 Athanasiou, L.V. . . . . . . . . . . . . . . . . . . . . P1433 Athani, A. . . . . . . . . . . . . . . . . . . . . . . . . eP558 Atherton, G.T. . . . . . . . . . . . . . . . . . . . . . .eP540 Athipanyasilp, N. . . . . . . . . . . . . . . . . . . . eP405 Atoyebi, O.A.. . . . . . . . . . . . . . . . . . . . . . .P0074 Attanasio, V. . . . . . . . . . . . . . . . . . . . . . . .P1455 Attili, A.R. . . . . . . . . . . . . . . . . . . . . . . . . P1646 Atukawa, Y. . . . . . . . . . . . . . . . . . . . . . . . P0491 Atun, R.. . . . . . . . . . . . . . . . . . . . . P0412, P1877 Aubin, G.G. . . . . . . . . . . . . . . . . . . . . . . . .eP049 Auboyer, C. . . . . . . . . . . . . . . . . . . . . . . . P0190 Aubrey-Jones, H. . . . . . . . . . . . . . . . . . . . eP272 Aubry, A. . . . . . . . . . . . . . . . . . . . . . . . . .P0359 Auburn, H. . . . . . . . . . . . . . . . . . . . . . . . . O004 Aucamp, M. . . . . . . . . . . . . . . . . . . . . . . .P1543 Augustijns, A. . . . . . . . . . . . . . . . . . . . . . .P1696 Augustin, V. . . . . . . . . . . . . . . . . . P0248, P0804 Augustynowicz-Kopec, E. . . . . . . . . . . . . . P0936 Aura, Y. . . . . . . . . . . . . . . . . . . . . . . . . . .P1802 Aurbach, U. . . . . . . . . . . . . . . . . . . . . . . . P0705 Aurora, P.. . . . . . . . . . . . . . . . . . . . . . . . P0885 24th ECCMID / Barcelona Final Programme 253 Exhibition NameNumber General Information NameNumber Chairs, Speakers & Authors List of Speakers & Authors List of Speakers & Authors NameNumber NameNumber NameNumber Ausín, F. . . . . . . . . . . . . . . . . . . . . P0972, P1899 Ausina, V. . . . . . . . . . . . . . . . . . . . P0914, P0917 Ausselet, N. . . . . . . . . . . . . . . . . . . . . . . eP398 Austin, B. . . . . . . . . . . . . . . . . . . . . . . . . P1616 Autenrieth, I.B. . . . . . . . . . . . . . . . . . . . . .P1779 Auxilia, F. . . . . . . . . . . . . . . . . . . . . . . . . P1000 Auzinger, G. . . . . . . . . . . . . . . . . . . . . . . . IS084 Auzou, M. . . . . . . . . . . . . . .P1526, P1548, P1565, P1566, P1791, P1793 Avdeenko, Y.L. . . . . . . . . . . . . . . . . . . . . . P0105 Avdic, E. . . . . . . . . . . . . . . . . . . . . . . . . P0536 Averbuch, D. . . . . . . . . . . . . . . . . . . . . . . P1342 Avi, R. . . . . . . . . . . . . . . . . . . . . . . . . . . .P1892 Avkan-Oguz, V. . . . . . . . . . . . . . . . . . . . . .P0477 Avni, T. . . . . . . . . . . . . . . . . . . . . . . . . . . O257 Avsic Zupanc, T. . . . . . . . . . . . . . . . . . . . .EW017 Awad-El-Kariem, F. . . . . . . . . . . . . . . . . . . .P0723 Ayas, R. . . . . . . . . . . . . . . . . . . . . . . . . . P0902 Ayats, J. . . . . . . . . . . . . . . . . . . . . O235, P0050 Aydemir, H. . . . . . . . . . . . . . . . . . . . . . . .P0461 Aydillo, T.A. . . . . . . . . . . . . . . . . . . . . . . . . O107 Aydin, E. . . . . . . . . . . . . . . . . . . . . . . . . .P1623 Aydin, G. . . . . . . . . . . . . . . . . . . . . P0210, P1062 Aydin, M. . . . . . . . . . . . . . . . . . . . . . . . . .eP277 Ayed, K. . . . . . . . . . . . . . . . . . . . . . . . . . P0690 Ayele, H. . . . . . . . . . . . . . . . . . . . . . . . . P0954 Aypak, A.. . . . . . . . . . . . . . . . . . . . . . . . .P1848 Aysegul, G. . . . . . . . . . . . . . . . . . . . . . . . eP358 Azad, M.A.K. . . . . . . . . . . . . . . . . . . . . . . . P1731 Azak, E. . . . . . . . . . . . . . . . . . . . . . . . . . P1933 Azanza, J.R. . . . . . . . . . . . . . . . . . . . . . . .P0013 Azcona-Gutiérrez, J.M. . . . . . . . . . . . . . . . .P1129 Azevedo, M.M. . . . . . . . . . . . . . . . . . . . . . P0320 Azevedo, T. . . . . . . . . . . . . . . . . . . . . . . . P0909 Azkune Galparsoro, H. . . . . . . . . . . . . . . . .eP569 Aznar Martín, J. . . . . . . . . . . . . . . . . . . . . P0583 Aznar, E. . . . . . . . . . . . . . . . . . . . . . . . . .P0872 Aznar, J. . . . . . . . . . . . eP117, O122, P0921, P1306 Azoulay, E. . . . . . . . . . . . . . . . . . . . . . . . eP365 Azouri, T. . . . . . . . . . . . . . . . . . . . . . . . . . eP214 Azzam, M. . . . . . . . . . . . . . . . . . . . . . . . .P1349 Azzam, Z.S. . . . . . . . . . . . . . . . . . . . . . . .P1349 B B.Savage, P. . . . . . . . . . . . . . . . . . . . . . . .P0312 Baaboura, R. . . . . . . . . . . . . . . . . . . . . . . eP503 Baadani, A.M. . . . . . . . . . . . . . . . . . . . . . eP206 Baba, K. . . . . . . . . . . . . . . . . . . . . . . . . . P1834 Babayigit, M.L. . . . . . . . . . . . . . . . . . . . . .eP585 Baber, J. . . . . . . . . . . . . . . . . . . . . eP134, eP146 Babich, T. . . . . . . . . . . . . . . . . . . . . . . . . . O257 Babini, G. . . . . . . . . . . . . . . . . . . . eP342, P0579 Babitsch, B. . . . . . . . . . . . . . . . . . . . . . . P0942 Bablishvili, N. . . . . . . . . . . . . . . . . . . . . . . O086 Baca, V. . . . . . . . . . . . . . . . . . . . . . . . . . .P0610 Bacchin, C. . . . . . . . . . . . . . . . . . . . . . . . P0793 Bacconi, A. . . . . . . . . . . . . . . . . . . . . . . . P0534 Bacescu, B. . . . . . . . . . . . . . . . . . . . . . . .P0634 Bachmann, T. . . . . . . . . . . . . . . . . . . . . . .P0230 Bachvarova-Nedelcheva, A. . . . . . . . . . . . . .P0313 Bäckström, T. . . . . . . . . . . . . . . . . . . . . . .P1670 Badal, R. . . . . . . . . . .eP437, eP439, P1055, P1072, P1078, P1082, P1202, P1588, P1593, P1615, P1778, P1781, P1782, P1783 Badal, R.E. . . . . . . . . . . . . . . . . . . .P0232, P0233 Badali, M.N. . . . . . . . . . . . . . . . . . . . . . . eP303 Baddour, L.M. . . . . . . . . . . . . . . . . . . . . . .eP120 Badiola, J. . . . . . . . . . . . . . . . . . . . . . . . . P1724 Badiou, C. . . . . . . . . . . . . . . . . . . . . . . . .P1557 Bador, J. . . . . . . . . . . . . . . . . . . . . . . . . . O199 Badowski, M. . . . . . . . . . . . . . . . . . . . . . .P1910 Badura, A. . . . . . . . . eP283, P1080, P1480, P1501 Badura, R. . . . . . . . . . . . . . . . . . . . . . . . .eP312 Bae, I. . . . . . . . . . . . . . . . . . . . . . . . . . . .eP550 Bae, I.G. . . . . . . . . . . . . . . . . . . . . . . . . . P0483 Baek, K.R. . . . . . . . . . . . . . . . . . . . . . . . .P1668 Baek, W.K. . . . . . . . . . . . . . . . . . . . . . . . . P0219 Baer, W. . . . . . . . . . . . . . . . . . . . . . . . . . P1372 Baglivo, E. . . . . . . . . . . . . . . . . . . P0838, P0875 Baguelin, M. . . . . . . . . . . . . . . . . . .eP131, P0452 Bahadir, F. . . . . . . . . . . . . . . . . . . . . . . . P0441 Bahlmann, A.S. . . . . . . . . . . . . . . . . . . . . .P0201 Bahr, V. . . . . . . . . . . . . . . . . . . . . . . . . . . O108 Bahra, M. . . . . . . . . . . . . . . . . . . . . . . . . . O170 Bahram, S. . . . . . . . . . . . . . . . . . . . . . . . P1407 Baier, M. . . . . . . . . . . . . . . . . . . . . . . . . P0969 Baier, V.. . . . . . . . . . . . . . . . . . . . . . . . . .P0625 Baietto, L. . . . . . . . . . . . . . . . . . . . P1705, P1728 Baig, K. . . . . . . . . . . . . . . . . . . . . . . . . . .eP524 Bailey, A.M. . . . . . . . . . . . . . . . . . . . . . . .P1103 Bailey, R. . . . . . . . . . . . . . . . . . . . . . . . . P1847 Bailly, S. . . . . . . . . . . . . . . . . . . . . . . . . . O232 Bajec, T. . . . . . . . . . . . . . . . . . . . . . . . . . P0363 Bak Pedersen, H. . . . . . . . . . P0368, P0371, P0373, P0374, P0377 Baka, S. . . . . . . . . . . . . . . . . . . . . . . . . . eP575 Baker, J.M.. . . . . . . . . . . . . . . . . . . . . . . .P0767 Baker, R. . . . . . . . . . . . . . . . . . . . . . . . . .P1874 Baker, S. . . . . . . . . . . . . . . . . . . . .P0146, P1839 Bakheshwain, S. . . . . . . . . . . . . . . . . . . . .eP373 Bakhshi-Raiez, F. . . . . . . . . . . . . . . . . . . . P1879 Bakir, M. . . . . . . . . . . . . . . . . . . . . . . . . .P1182 Bakker-Schut, T. . . . . . . . . . . . . . . . P1509, P1785 Bakossi, A. . . . . . . . . . . . . . . . . . . . . . . . eP255 Bakula, Z. . . . . . . . . . . . . . . . . . . . P0933, P0936 Bala, K. . . . . . . . . . . . . . . . . . . . . . . . . . .P0071 Balabolkin, I. . . . . . . . . . . . . . . . . . . . . . . P1244 Balada-Llasat, J.M. . . . . . . . . .O009, P0211, P0542 Balakhonov, S. . . . . . . . . . . . . . . . . . . . . eP466 Balakrishnan, I. . . . . . . . . . . . . . . . eP316, eP338 Balato, G. . . . . . . . . . . . . . . . . . . . . . . . . eP055 Balay, K. . . . . . . . . . . . . . . . . . . . . . . . . . P1416 Balbier, S. . . . . . . . . . . . . . . . . . . . . . . . . P0866 Balcioglu, I.C. . . . . . . . . . . . . . . . . . . . . . .P0673 Baldanti, F.. . . . O225, P0462, P0473, P1382, SY256 Baldassarri, L. . . . . . . . . . . . . . . . . . . . . . P0204 Baldin, C.P. . . . . . . . . . . . . . . . . . . . . . . . . O050 Balfagón, P. . . . . . . . . . . . . . . . . . .P1380, P1388 Balik, I. . . . . . . . . . . . . . . . . . . . . . . . . . . P0210 Balkan, I.I. . . . . . . . . . . . . . . . . . . . eP354, O093 Ball, J. . . . . . . . . . . . . . . . . . . . . . . . . . . P1875 Ballard, M. . . . . . . . . . . . . . . . . . . . . . . . P0595 Ballereau, F. . . . . . . . . . . . . . . . . . . . . . . .P1058 Ballesta, S. . . . . . . . . . . . . . . . . . . . . . . . P0385 Ballester, B. . . . . . . . . . . . . . . . . . . . . . . .P1396 Ballester, E. . . . . . . . . . . . . . . . . . . . . . . .P1825 Ballester, F. . . . . . . . . . . . . . . . . . . . . . . . P0132 Ballesteros, J. . . . . . . . . . . . eP570, P1901, P1908 Balloco, C. . . . . . . . . . . . . . . . . . . . . . . . .eP574 Balode, A. . . . . . . . . . . . . . . . . . . . . . . . . P1015 Balode, A.O. . . . . . . . . . . . . . . . . . . . . . . .P0501 Baltar, P. . . . . . . . . . . . . . . . . . . . . . . . . P0904 Baluya, D. . . . . . . . . . . . . . . . . . . . . . . . .P1733 Bamford, K.B. . . . . . . . . . . . . . . . . . . . . . . O048 Banaszewska, B. . . . . . . . . . . . . . . . . . . . eP578 Banche, G. . . . . . . . . . . . . . . . . . . . . . . . .P0133 Bandettini, R. . . . . . . . . . . . . . . . . . . . . . .P1869 Bandi, C. . . . . . . . . . . . . . . . . . . . . . . . . .P0612 Bandyopadhyaya, R. . . . . . . . . . . . . . . . . P0930 Banfield, S. . . . . . . . . . . . . . . . . . . . . . . . eP540 Banifazl, M. . . . . . . . . . . . . . . . . . . . . . . .P1833 Banjanac, M. . . . . . . . . . . . . . . . . . . . . . .P0143 Banks, A. . . . . . . . . . . . . . . . . . . . . . . . . .O005 Bano, L. . . . . . . . . . . . . . . . . . . . . . . . . . P0793 Bansal, V. . . . . . . . . . . . . . . . . . . . . . . . . P1384 Bañuls, A.L. . . . . . . . . . . . . . . . . . P0945, P0946 Banzola, N. . . . . . . . . . . . . . . . . . . eP557, eP564 Bao, L. . . . . . . . . . . . . . . . . . . . . . . . . . .P0973 Baptista-Fernandes, T. . . . . . . . . . . . . . . . .eP584 Baque, A. . . . . . . . . . . . . . . . . . . . . . . . . P0574 Baquero, F.. . . . eP612, KL152, P0164, P1109, P1155, P1157, P1239, P1240, P1241, P1552, P1652 Baquero, M.R. . . . . . . . . . . . . . . . . . . . . . .P0164 Barahona, M.J. . . . . . . . . . . . . . . . . . . . . .P0397 Baran, A.I. . . . . . . . . . . . . . . . . . . . . . . . .P1835 Baran, I. . . . . . . . . . . . . . . . . . . . . . . . . P1006 Baraniak, A. . . . . . . . . . . . . . . . . . .P1205, P0353 Baranov, A. . . . . . . . . . . . . . . . . . . . . . . . P1244 Baratin, D. . . . . . . . . . . . . . . . . . . . . . . . .P1379 Barba Sunol, P. . . . . . . . . . . . . . . . . . . . . .eP372 Barba, P. . . . . . . . . . . . . . . . . . . . . P1242, P1271 Barbabosa Pliego, A. . . . . . . . . . . . . . . . . . P0108 Barbanti, F. . . . . . . . . . . . . . P0382, P0758, P0827 Barbarini, D.. . . . . . . . eP465, eP611, P0354, P1184 Bárbaro Del Negro, G.M. . . . . . . . . . . . . . . . P0034 Barbeito Castiñeiras, G. . . . . . . . . . . . . . . . P1352 Barbeito, G. . . . . . . . . . . . . . . . . . . . . . . P0904 Barber, A. . . . . . . . . . . . . . . . . . . . . . . . . P1875 Barber, K. . . . . . . . . . . . . . . eP177, eP194, eP425 Barbera, M. . . . . . . . . . . . . . . . . . . . . . . .P0573 Barbera, M.J. . . . . . . . . . . . . . . . . . . . . . .P0975 Barberá, V.M. . . . . . . . . . . . . . . . . . . . . . P0608 Barberán, J. . . . . . . . . . . . . . . . . . . . . . . P0520 Barbero, J. . . . . . . . . . . . . . . . . . . . . . . . P0569 Barbeschi, M. . . . . . . . . . . . . . . . . . . . . . .TD102 Barbic, L. . . . . . . . . . . . . . . . . . . . . . . . .P0449 Barbic, L.J. . . . . . . . . . . . . . . . . . . . . . . . P0434 Barbosa, M. . . . . . . . . . . . . . . . . . P0645, P0650 Barbosa, S. . . . . . . . . . . . . . . . . . . P1022, P1101 Barbui, A.M. . . . . . . . . . . . . . . . . . . . . . . .P1807 Barbut, F. . . . . . . . . .P0736, P0740, P0744, P0760, P0777, P0786, P0805, P0822, SY241 Barcena, R. . . . . . . . . . . . . . . . . . . P1912, P1914 Barchitta, M. . . . . . . . . . . . . . . . . . P0547, P1000 Bardají, A. . . . . . . . . . . . . . . . . . . . . . . . . P1261 Bardaro, M. . . . . . . . . . . . . . . . . . . . . . . . P0354 Bardel, C. . . . . . . . . . . . . . . . . . . . . . . . . P0152 Bardi, R. . . . . . . . . . . . . . . . . . . . . . . . . P0690 Bardon, J. . . . . . . . . . . . . . . . . . . .P0832, P1067 Barekova, L. . . . . . . . . . . . . . . . . . . . . . . P0779 Barelli, A. . . . . . . . . . . . . . . . . . . . . O166, P1895 Bargui, H. . . . . . . . . . . . . . . . . . . . . . . . .P0604 Barie, P.S. . . . . . . . . . . . . . . . . . . . . . . . . IS108 Barisic, I.. . . . . . . . . . . . . . . . . . . . . . . . P0599 Barisic, N. . . . . . . . . . . . . . . . . . . . . . . . . P1612 Barkay, O. . . . . . . . . . . . . . . . . . . .eP581, P0418 Barker, K. . . . . . . . . . . . . . . . . . . . . . . . . P0020 Barker, K.S. . . . . . . . . . . . . . . . . . . . . . . .eP237 Barker, M. . . . . . . . . . . . . . . . . . . . . . . . eP344 Barkhausen, S. . . . . . . . . . . . . . . . . . . . . . O126 Barlavie, Y. . . . . . . . . . . . . . . . . . . . . . . . eP030 Barmpouti, E. . . . . . . . . . . . . . . . . . . . . . .eP421 Barnaud, G. . . . . . . . . . . . . . . . . . . P0487, P1354 Barnes, K. . . . . . . . . . . . . . . . . . . . P0110, P0241 Barnes, R. . . . . . . . . . . . . . . . . . . . . . . . . .O217 Baroli, K. . . . . . . . . . . . . . . . . . . . . . . . . P0982 Baron, S. . . . . . . . . . . . . . . eP128, P0500, eP058 Baroni, D. . . . . . . . . . . . . . . . . . . . . . . . . P0722 254 24th ECCMID / Barcelona Final Programme NameNumber Barons, S. . . . . . . . . . . . . . . . . . . . . . . . eP022 Barr, V. . . . . . . . . . . . . . . . . . . . . eP422, eP425 Barrabeig, I. . . . . . . . . . . . . . . . . . . . . . . . P1361 Barrailler, S. . . . . . . . . . . . . . . . . . . . . . . .eP411 Barras, C. . . . . . . . . . . . . . . . . . . . . . . . . eP180 Barreiros, G.. . . . . . . . . . . . . . . . . . . . . . .eP368 Barrera, A. . . . . . . . . . . . . . . . . . . . . . . . .eP392 Barrero, L. . . . . . . . . . . . . . . . . . . . . . . . .P1020 Barrett, M. . . . . . . . . . . . . . . . . . . . . . . . eP066 Barriere, S. . . . . . . . . . . . . . . . . . . . . . . . P1722 Barriere, S.L. . . . . . . . . . . . . . . . . . . . . . . . O153 Barroco, C. . . . . . . . . . . . . . . . . . . . . . . . P1592 Barron, M. . . . . . . . . . . . . . . . . . . . . . . . .P1003 Barros, E. . . . . . . . . . . . . . . . . . . . . . . . . P1146 Barros, J. . . . . . . . . . . . . . . . . . . . . . . . . P0320 Barros, M. . . . . . . . . . . . . . . . . . . . . . . . . O139 Barth, A. . . . . . . . . . . . . . . . . . . . . . . . . .eP341 Barth, A.L. . . . . . . . . . . . . . . . . . . . . . . . .P1093 Barth, S. . . . . . . . . . . . . . . . . . . . . . . . . P0626 Bartholomew, J. . . . . . . . . . . . . . . . . . . . .eP540 Bartholomew, J.S. . . . . . . . . . . . . . . . . . . . P0271 Bartizal, K. . . . . . . . . . . . . . . . . . . . . . . . P1674 Bartlett, J. . . . . . . . . . . . . . . . . . . . . . . . .P0773 Bartlett, J.A. . . . . . . . . . . . . . . . . . . . . . . P1907 Bartoletti, M. . . . . . . . . . . . . . . . . . . . . . eP530 Bartoletti, R. . . . . . . . . . . . . . . . . . eP297, P0511 Bartolome, R. . . . . . . . . . . . P0975, P0831, P0995 Bartolomé, R.M. . . . . . . . . . . . . . . . . . . . . P0845 Bartolomé-Álvarez, J.. . . . . . . . . . . . . . . . . P1817 Bartoloni, A. . . . . . . . . . . . . . . . . . . . . . . .P0811 Barton, R. . . . . . . . . . . . . . . . . . . . eP377, eP455 Bartosik, D. . . . . . . . . . . . . . . . . . . P1135, P1140 Bartsch, S. . . . . . . . . . . . . . . . . . . . . . . . .O109 Bartzavali, C. . . . . . . . . . . . . . . . . . eP607, eP608 Baruschke, K. . . . . . . . . . . . . . . . . P0813, P1376 Barzilay, O. . . . . . . . . . . . . . . . . . . . O179, P1488 Barzon, L. . . . . . . . . . . . . . . . . . . . . O226, O227 Basanisi, M.G. . . . . . . . . . . . . . . . . . . . . . P1660 Basas, J. . . . . . . . . . . . . . . . . . . . . . . . . P0222 Basas, M. . . . . . . . . . . . . . . . . . . . P1709, P1727 Bashir, A. . . . . . . . . . . . . . . . . . . . P1031, P1218 Basireddy, S. . . . . . . . . . . . . . . . . . . . . . .P1069 Basit, A. . . . . . . . . . . . . . . . . . . . . . . . . .P0806 Basma, M. . . . . . . . . . . . . . . . . . . . . . . . P0603 Bassal, R. . . . . . . . . . . . . . . . . . . P0446, P0448 Bassetti, D. . . . . . . . . . . . . . . . . . . . . . . . P1421 Bassetti, M. . . . . . . . . . . . . eP445, eP446, EW047, IS050, IS067, P0260 Basso, M. . . . . . . . . . . . . . . . O166, P1895, P1915 Bastida, M.T. . . . . . . . . . . . . . . . . . . . . . . P1830 Bastides, F. . . . . . . . . . . . . . . . . . . eP432, P1672 Bastien, F. . . . . . . . . . . . . . . . . . . . . . . . .P0672 Bastien, P. . . . . . . . . . . . . . . . . . . . . . . . . O059 Bastug, A. . . . . . . . . . . . . . . . . . . . . . . . P1006 Bataille, B. . . . . . . . . . . . . . . . . . . . . . . . .eP041 Batard, E. . . . . . . . . . . . . . . eP065, P1336, P1842 Bateman, V. . . . . . . . . . . . . . . . . . . . . . . P0959 Bateson, A. . . . . . . . . . . . . . . . . . . . . . . . P0961 Bathina, P. . . . . . . . . . . . . . . . . . . . . . . . .P0255 Batirel, A. . . . . . . . . . .O093, P1606, P1835, P1840 Batischeva, G. . . . . . . . . . . . . . . . . . . . . . P0370 Batista, M. . . . . . . . . . . . . . . . . . . . . . . . P0052 Batlle, M. . . . . . . . . . . . . . . . . . . . . . . . . . P1275 Batra, P. . . . . . . . . . . . . . . . . . . . . . . . . . P1075 Bätzing-Feigenbaum, J. . . . . . . . . . . . . . . .eP168 Baud, D. . . . . . . . . . . . . . . . . . . . . . . . . . P0196 Bauer, K. . . . . . . . . . . . . . . . . . . . . . . . . . eP512 Bauer, K.A. . . . . . . . . . .eP476, eP484, O009, P1571 Bauer, M.P. . . . . . . . . . . . . . . . . . . . . . . . .P0251 Baumann, B. . . . . . . . . . . . . . . . . . . . . . . P1637 Bauraing, C. . . . . . . . . . . . . . P1051, P1079, P1648 Bautista, V. . . . . . . . . . . . . . . . . . . . . . . . eP328 Bauwens, M.A. . . . . . . . . . . . . . . . . . . . . . P1711 Baxter, M. . . . . . . . . . . . . . . . . . . . . . . . P1086 Bayer, A. . . . . . . . . . . . . . . . . . . . . . . . . . O252 Bayindir, Z. . . . . . . . . . . . . . . . . . . P0210, P1062 Baykam, N. . . . . . . . . . . . . . . . . . . . . . . .P1848 Baylan, O. . . . . . . . . . . . . . . . . . . . . . . . P0628 Baymakova, M.. . . . . . . . . . . . . . . P1804, P1922 Baynes, D. . . . . . . . . . . . . . . . . . . . . . . . .P1427 Bayram, N. . . . . . . . . . . . . . . . . . . . . . . . eP401 Bayston, R. . . . . . . . . . . . . . . . . . . . . . . . IS015 Baza, B. . . . . . . . . . . . . . . . . . . . . . . . . . .O168 Baziaka, F. . . . . . . . . . . . . . . . . . . . eP421, P0131 Beach, K. . . . . . . . . . . . . . . . . . . . . . . . . .O073 Beacham, I. . . . . . . . . . . . . . . . . . . . . . . . O222 Beader, N. . . . . . . . . . . . . . . P1210, P1612, P1921 Beardsley, J. . . . . . . . . . . . . . . . . . . . . . . P0075 Beato, J. . . . . . . . . . . . . . . . . . . . . . . . . .P1803 Beatobe, L. . . . . . . . . . . . . . . . . . . . . . . . eP597 Beatson, S. . . . . . . . . . . . . . . . . . . . . . . . P0168 Beaz-Hidaldo, R. . . . . . . . . . . . . . . . . . . . . eP471 Bebear, C. . . . . . . . . . . . . . .eP566, P0736, P1142 Becheker, I. . . . . . . . . . . . . . . . . . . . . . . P0690 Beck, E. . . . . . . . . . . . . . . . . . . . . . . . . . . O074 Becker, G. . . . . . . . . . . . . . . . . . . . . . . . . eP610 Becker, J. . . . . . . . . . . . . . . . . . . . P0763, P1611 Becker, K. . . . . . . . . . . eP166, eP279, O171, P0350 Becker, M. . . . . . . . . . . . . . . . . . . .P0814, P0825 Beclin, E.. . . . . . . . . . . . . . . . . . . . . . . . P0505 Bedenic, B. . . . . . . . . . . . . . . . . . . P1210, P1612 Bedford, L.J. . . . . . . . . . . . . . . . . . . . . . . P1789 Bedin Denardi, L. . . . . . . . . . . . . . . . . . . . P0023 Bedini, A. . . . . . . . . . . . . . . . . . . . eP568, P1824 Bedlotti, P.T. . . . . . . . . . . . . . . . . . . . . . . .P1139 Bedoya, G. . . . . . . . . . . . . . . . . . . . . . . . .P0932 Beeching, N. . . . . . . . . . . . . . . . . . . . . . . P1344 Beeching, N.J. . . . . . . . . . . . . . . . .EW058, SY153 Beer, M. . . . . . . . . . . . . . . . . . . . . . . . . . SY114 Beezer, A. . . . . . . . . . . . . . . . . . . . . . . . .P0806 Béguelin, C. . . . . . . . . . . . . . . . . . . . . . . .eP085 Begum, J. . . . . . . . . . . . . . . . . . . . . . . . . O264 Begum, S. . . . . . . . . . . . . . . . . . . . . . . . .P0314 Behets, F. . . . . . . . . . . . . . . . . . . . . . . . . P1916 Behnke, M. . . . . . . . . . . . . . . .eP011, O129, O197, P0754, P0755, P1040 Behnood, V. . . . . . . . . . . . . . . . . . . . . . . . P1112 Beiboer, S. . . . . . . . . . . . . . . . . . . . . . . . .P1443 Bekcibasi, M. . . . . . . . . . . . . . . . . . . . . . P0699 Bekker, A. . . . . . . . . . . . . . . . . . . . . . . . .P1543 Belabbes, H. . . . . . . . . . . . . . . . . . . . . . . eP152 Belanov, S. . . . . . . . . . . . . . . . . . . . . . . . P1446 Belausov, N. . . . . . . . . . . . . . . . . . . . . . . .P1569 Belaz, S. . . . . . . . . . . . . . . . . . . . . P0676, P0717 Belcheva, M. . . . . . . . . . . . . . . . . . . . . . . P0318 Belesiotou, E. . . . . . . . . . . . . . . . . .P0081, P1181 Belgacem, O. . . . . . . . . . . . . . . . . . . . . . . eP338 Belhani, M. . . . . . . . . . . . . . . . . . . . . . . . P1238 Belhiba, M. . . . . . . . . . . . . . . . . . . . . . . . P0348 Belinchón, R. . . . . . . . . . . . . . . . . . . . . . .P0701 Belkasim-Bohoudi, H.. . . . . . . . . . . . . . . . . P1232 Belkova, Y. . . . . . . . . . . . . . . . . . . . . . . . .P0370 Bell, R. . . . . . . . . . . . . . . . . . . . . . . . . . .P1263 Bella, F. . . . . . . . . . . . . . . . . . . . . . . . . . .P0419 Bellavista, S. . . . . . . . . . . . . . . . . . . . . . . eP564 Bellesi, J. . . . . . . . . . . . . . . . . . . . . . . . . P1524 Belley, A. . . . . . . . . . . . . . . . . . . . . . . . . . eP174 Bellini, F. . . . . . . . . . . . . . . . . . . . . P0728, P1871 Bello Gonzalez, T. . . . . . . . . . . . . . . . . . . . eP493 Bello, F. . . . . . . . . . . . . . . . . . . . . . . . . . .P1638 Bellopede, P. . . . . . . . . . . . . . . . . . . eP212, O092 Bellou, M. . . . . . . . . . . . . . . . . . . . O228, P0442 Belmar Campos, C. . . . . . . . . . . . . . . . . . . P1120 Belmatoug, N. . . . . . . . . . . . . . . . . . . . . . .O258 Belmekki, M. . . . . . . . . . . . . . . . . . . . . . . P0823 Belmouaz, S. . . . . . . . . . . . . . . . . . . . . . . P1711 Belotcerkovskaya, E. . . . . . . . . . . . . . . . . eP386 Beltran, M.. . . . . . . . . . . . . . . . . . . . . . . .P1020 Beltrán-Alzate, J.C. . . . . . . . . . . . . . . . . . . P0932 Beltrán-Cifuentes, I. . . . . . . . . . . . . . . . . . . P1817 Beltrand, E. . . . . . . . . . . . . . . . . . . . . . . P0266 Belvisi, L. . . . . . . . . . . . . . . . . . . . P0887, P1936 Belzer, C. . . . . . . . . . . . . . . . . . . . . . . . . .P0118 Bemer, P. . . . . eP049, eP410, P0896, P0818, P0952 Ben Abdallah, H. . . . . . . . . . . . . . . . . . . . .P1832 Ben Aissa, I. . . . . . . . . . . . . . . . . . . . . . . P0092 Ben Amara, A.. . . . . . . . . . . . . . . . . . . . . .P1256 Ben Amor, S. . . . . . . . . . . . . . . . . . . . . . . P0290 Ben Brahim, H. . . . . . . . . . . . . . . . . . . . . .P1832 Ben Hassen, A. . . . . . . . . . . . . . . . . . . . . .eP503 Ben Jazia, E. . . . . . . . . . . . . . . . . . . . . . . P1955 Ben Jemaa, M. . . . . . . . . . . . . . . . . . . . . .eP122 Ben Kahla, S. . . . . . . . . . . . . . . . . . . . . . .eP122 Benajah, D.A. . . . . . . . . . . . . . . . . . . . . . .P0873 Ben-Ami, R. . . . . . . . . . . . . . . O082, O123, P0104 Benard, G. . . . . . . . . . . . . . . . . . . . . . . . P0034 Benavent, E. . . . . . . . . . . . . . . . . . . . . . . P1457 Ben-Chetrit, E. . . . . . . . . . . . . . . . . . . . . . .O008 Benck, U. . . . . . . . . . . . . . . . . . . . . . . . . P1277 Bendall, R.P. . . . . . . . . . . . . . . . . . . . . . . .P1815 Bender, J. . . . . . . . . . . . . . . . . . . . . . . . . . O137 Bendfeldt, H. . . . . . . . . . . . . . . . . . . . . . .P1389 Bendjama, E.S.M.A. . . . . . . . . . . . . . P0327, P0328 Benea, S.. . . . . . . . . . . . . . . . . . . . . . . . .P0761 Benedetti, I. . . . . . . . . . . . . . . . . . . . . . . .eP019 Benedetti, P. . . . . . . . . . . . . . . . . . . . . . . P0953 Benenson, S. . . . . . . . . . . . . . . . . . . . . . eP596 Benes, J. . . . . . . . . . . . . . . . . . . . . . . . . eP309 Bénet, T. . . . . . . . . . . . . . . . . . . . . eP276, O195 Benfield, T. . . . . . . . . . . . . . . . . . . . . . . . P0073 Benhar, I. . . . . . . . . . . . . . . . . . . . . . . . . P0104 Benito, D. . . . . . . . . . . . . . . . . . . . . . . . . P1556 Benito, N. . . . . . . . . . . . . . . . . . . . . . . . . P0525 Benito, Y. . . . . . . . . . . . . . . . . . . . . . . . . .P0623 Benito-Pascual, D. . . . . . . . . . . . . . . . . . . .P1653 BenLaifa, M.. . . . . . . . . . . . . . . . . . . . . . P0690 Bennani, B. . . . . . . . . . . . . . . . . . . . . . . .P0873 Bennett, C. . . . . . . . . . . . . . . . . . . . . . . . .O068 Bennett, H. . . . . . . . . . . . . . . . . . . P0337, P0492 Bennett, M. . . . . . . . . . . . . . . . . . . . . . . EW063 Bennett, T. . . . . . . . . . . . . . . . . . . . . . . . .P0411 Benninga, M.A. . . . . . . . . . . . . . . . . . . . . . O203 Benzonana, N. . . . . . . . . . . . . . . . . . . . . .P1606 Beovic, B. . . . . . . . . . . O251, P0268, P1283, P1570 Ber, C.. . . . . . . . . . . . . . . . . . . . . . . . . . .P0031 Beran, O. . . . . . . . . . . . . . . . . . . . . . . . . eP309 Beran, V. . . . . . . . . . . . . . . . . . . . . . . . . .P0779 Berard, X. . . . . . . . . . . . . . . . . . . . . . . . . P0349 Béraud, G. . . . . . eP041, O251, P1450, P1711, P1828 Berciu, I. . . . . . . . . . . . . . . . . . . . . . . . . .eP029 Bercot, B. . . . . . P0974, P0977, P0978, eP231, O183 Bereciartua-Bastarrica, E. . . . . . . . . . . . . . .P0577 Berenger, B. . . . . . . . . . . . . . . . . . .eP192, P1294 Bereswill, S. . . . . . . . . . . . . . . . . . . . . . . .P0119 Bereszynska, I. . . . . . . . . . . . . . . . P1946, P1952 Berezhanskiy, B. . . . . . . . . . . . . . . . . . . . eP205 Berg, J. . . . . . . . . . . . . . . . . . . . . . . . . . .P1647 24th ECCMID / Barcelona Final Programme 255 Exhibition NameNumber General Information NameNumber Chairs, Speakers & Authors List of Speakers & Authors List of Speakers & Authors NameNumber NameNumber NameNumber Bergamaschi, R. . . . . . . . . . . . . . . . . . . . .P1293 Berger, A. . . . . . . . . . . . . . . . . . . . . . . . . P0623 Berger, C. . . . . . . . . . . . . . . . . . . . . . . . . P1504 Bergeron, A. . . . . . . . . . . . . . . . . . . . . . . .eP365 Bergeron, E. . . . . . . . . . . . . . . . . . . . . . . P0609 Bergerova, T. . . . . . . . . . . . . . . . . . . . . . . P1090 Bergin, C. . . . . . . . . . . . . . . . . . . . . . . . . P1249 Bergmann, L. . . . . . . . . . . . . . . . . . . . . . .P0258 Bergval, I. . . . . . . . . . . . . . . . O039, O086, P0884 Berhelot, P. . . . . . . . . . . . . . . . . . . . . . . . P0190 Berhin, C. . . . . . eP331, O158, P1079, P1209, P1648 Beristain Rementería, X. . . . . . . . . . . . . . . .P1773 Berkow, E.L. . . . . . . . . . . . . . . . . . . . . . . .eP237 Berkoz, M. . . . . . . . . . . . . . . . . . . . . . . . P0407 Berlingeri, A. . . . . . . . . . . . . . . . . . . . . . . eP325 Berman, J.. . . . . . . . . . . . . . . . . . . . . . . . O082 Bermudez, C. . . . . . . . . . . . . . . . . . . . . . .P1300 Bermudez, D.C. . . . . . . . . . . . . . . . . . . . . .eP051 Bern, C.. . . . . . . . . . . . . . . . . . . . . . . . . .SY201 Bernabé, C. . . . . . . . . . . . . . . . . . . . . . . .P1134 Bernard, C. . . . . . . . . . . . . . . . . . . .O088, P0359 Bernard, L. . . . . . . . . . . . . .eP128, P0500, P0512, eP432, O258, P1672 Bernardi, S. . . . . . . . . . . . . . . . . . . . . . . .P1851 Bernardini, F. . . . . . . . . . . . . . . . . . . . . . P0302 Bernardo, A. . . . . . . . . . . . . . . . . . . . . . . .P1455 Bernardo, P. . . . . . . . . . . . . . . . . . . . . . . .eP450 Bernaschi, P. . . . . . . . . O202, P1524, P1850, P1867 Bernasconi, D. . . . . . . . . . . . . . . . . . . . . .P0339 Bernitzky, D. . . . . . . . . . . . . . . . . . . . . . . P0090 Bernusset, S. . . . . . . . . . . . . . . . . . . . . . .P1089 Berredjem, H. . . . . . . . . . . . . . . . . . . . . . P0690 Berriche, A. . . . . . . . . . . . . . . . . . . . . . . P0420 Berrilli, F. . . . . . . . . . . . . . . . . . . . . . . . . .P0651 Berscheid, A. . . . . . . . . . . . . . . . . . . . . . .P0311 Bertaina, C. . . . . . . . . . . . . . . . . . . . . . . .P1867 Bertaová, G. . . . . . . . . . . . . . . . . . . . . . . .P1245 Berth, M. . . . . . . . . . . . . . . . . . . . . . . . . . P1772 Berthelot, P. . . . . . . . . . . . . . . . . . . . . . . .P0417 Berthod, D. . . . . . . . . . . . . . . . . . . . O104, O105 Bertisch, B. . . . . . . . . . . . . . . . . . . . . . . .P1625 Bertoloni, G. . . . . . . . . . . . . . . . . . . . . . . P0009 Bertrand, X. . . . . . . . . . . . . . . . . . . P0376, P1512 Bertsch, D. . . . . . . . . . . . . . . . . . . . . . . . P1753 Bertsch, T. . . . . . . . . . . . . . . . . . . . . . . . .P0134 Berza, N. . . . . . . . . . . . . . . . . . . . . . . . . .P0316 Bes, M. . . . . . . . eP073, O186, P0191, P1557, P1561 Bessede, E. . . . . . . . . . . . . . . . . . . . . . . EW022 Besseling-van der Vaart, I.. . . . . . . . . . . . . .eP492 Best, E.L. . . . . . . . . . . . . . . . . . . . . . . . . P0801 Bestepe Dursun, Z. . . . . . . . . . . . . . . . . . P0441 Besutti, V. . . . . . . . . . . . . . . . . . . . . . . . P0708 Beteta, A. . . . . . . . . . . . . . . . . . . . . . . . . eP395 Betta, P. . . . . . . . . . . . . . . . . . . . . . . . . . P0035 Bettiol, E. . . . . . . . . . . . . . . . . . . . . . . . . P0295 Betts, J.W. . . . . . . . . . . . . . . . . . . . . . . . .P0319 Beucher, A. . . . . . . . . . . . . . . . . . . . . . . . eP089 Beumier, M. . . . . . . . . . . . . . . . . . . . . . . eP008 Beuret, C.M. . . . . . . . . . . . . . . . . . . . . . . P0405 Bevivino, A. . . . . . . . . . . . . . . . . . . . . . . . O099 Bexley, A. . . . . . . . . . . . . . . . . . . . . . . . . . O177 Beyeme, J.O. . . . . . . . . . . . . . . . . . . . . . . O022 Beyersdorf, F. . . . . . . . . . . . . . . . . . . . . . .eP026 Beyrouthy, R. . . . . . . . . . . . . . . . . . . . . . .P1032 Bezzi, C. . . . . . . . . . . . . . . . . . . . . . . . . . P1421 Bhakdeenuan, P. . . . . . . . . . . . . . . . . . . . P0433 Bhakta, S. . . . . . . . . . . . . . . . . . . . . . . . . O087 Bharathan, B. . . . . . . . . . . . . . . . . . . . . . .eP335 Bhatnagar, J. . . . . . . . . . . . . . . . . . . . . . . P1315 Bhavnani, S. . . . . . . . . . . . . . . . . . . . . . . P1743 Bianchi, G. . . . . . . . . . . . . . . . . . . . . . . . . .O212 Bianchi, S. . . . . . . . . . . . . . . . . . . . . . . . .P1768 Bianco, G. . . . . . . . . . . . . . . . . . . . . . . . .eP574 Bicanic, T. . . . . . . . . . . . . . . . . . . . . . . . . O238 Bicart See, A. . . . . . . . . . . . . . . . . . . . . . eP228 Bidet, P. . . . . . . . . . . . . . . . . . . . . . . . . . P1856 Bidoli, E. . . . . . . . . . . . . . . . . . . . . . . . . .P1909 Biedenbach, D. . . . . . .eP437, eP439, P1068, P1074, P1085, P1144, P1202, P1479, P1588, P1593, P1596, P1615, P1778, P1781, P1782, P1783 Biehl, L. . . . . . . . . . . . . . . . . . . . . . . . . . P0784 Biehler, K. . . . . . . . . . . . . . . . . . . . . . . . P0306 Bielecki, J. . . . . . . . . . . . . . . . . . . P0933, P0936 Bielicki, J. . . . . . . . . . . . . . . . . . . . . . . . . O209 Bielli, A. . . . . . . . . . . . . . . . . . . . . . . . . . P0336 Bielosludtseva, K. . . . . . . . . . . . . . . . . . . .P1348 Bien, P. . . . . . . . . . . . . . . . . . . . . . . . . . . P1674 Biendo, M. . . . . . . . . . . . . . .P0823, P1531, P1558 Bientz, L. . . . . . . . . . . . . . . . . . . . . . . . . P1142 Bienvenu, A.L. . . . . . . . . . . . . . . . . . . . . .P0044 Biezen v d-Brinkman, M. . . . . . . . . . . . . . . . P0714 Biggiogera, M. . . . . . . . . . . . . . . . . . . . . . P0007 Biglino, A. . . . . . . . . . . . . . . . . . . . . . . . P0556 Bijlmer, H.A. . . . . . . . . . . . . . . . . . . . . . . .P1259 Bilavsky, E. . . . . . . . . . . . . . . . . . .P1609, P1861 Biliotti, E. . . . . . . . . . . . . . . . . . . . P0476, P1938 Biljana Curcic-Trajkovska, B. . . . . . . . . . . . . P0395 Bilkert-Mooiman, M.. . . . . . . . . . . . . . . . . . O130 Billard-Pomares, T. . . . . . . . . . . . . . . . . . . P0487 Billinis, C. . . . . . . . . . . . . . . . . . . . . . . . . P1433 Billon, L. . . . . . . . . . . . . . . . . . . . . . . . . .P1843 Billström, H. . . . . . . . . . . . . . . . . . . . . . . P1500 Bilocq, F. . . . . . . . . . . . . . . . . . . . .P1644, P1645 Binda, S. . . . . . . . . . . . . . . . . . . . . . . . . . P1412 Bindschedler, M. . . . . . . . . . . . . . . . . . . . . eP412 Binh, P.T. . . . . . . . . . . . . . . . . . . . . . . . . .P1587 Bins, A.D. . . . . . . . . . . . . . . . . . . . . . . . .P0428 Biomón, R. . . . . . . . . . . . . . . . . . . . . . . . P0970 Birangwa, J.d. . . . . . . . . . . . . . . . . . . . . .P0899 Birgand, G.. . . . . . . . . . . . . . . . . . . . . . . . P1217 Birmpa, A. . . . . . . . . . . . . . . . . . . . . . . . . O228 Bishara, J. . . . . . . . . . . . . . . . . . . . . . . . . eP210 Bisnauthsing, K. . . . . . . . . . . . . . . . . . . . .P0772 Bissoli, L.R. . . . . . . . . . . . . . . . . . . . . . . .eP388 Biswas, J. . . . . . . . . . . . . . . . . . . . . . . . .P0772 Biteker, F. . . . . . . . . . . . . . . . . . . . . . . . .P0999 Bittel, P. . . . . . . . . . . . . . . . . . . . . . . . . . P0878 Bitzani, M. . . . . . . . . . . . . . . . . . . . . . . . . eP412 Bjarnsholt, T. . . . . . . . . . . . . . . . . . . . . . EW035 Bjerklund Johansen, T. . . . . . . . . . . . . . . . .P0511 Björk, D. . . . . . . . . . . . . . . . . . . . .eP529, eP534 Björkhem Bergman, L. . . . . . . . . . . . . . . . .P1670 Björkholm, M.. . . . . . . . . . . . . . . . . . . . . . O233 Björnsdóttir, E.S. . . . . . . . . . . . . . . P0592, P1505 Blagosklonov, O. . . . . . . . . . . . . . . . . . . . P0642 Blaich, A. . . . . . . . . . . . . . . . . . . . . . . . . .P1403 Blair, J. . . . . . . . . . . . . . . . . . . . . . . . . . .P1103 Blakiston, M. . . . . . . . . . . . . . . . . . . . . . .P0971 Blanc, D.S. . . . . . . . . . . . . . . . . . . . P1191, P1624 Blanchi, J. . . . . . . . . . . . . . . . . . . . . . . . .P0736 Blanco Hernandez, E. . . . . . . . . . . . . . . . . .eP054 Blanco Lobo, P. . . . . . . . . . . . . . . . . . . . . .P1306 Blanco, J.L. . . . . . . . . . . . . . . . . . . . . . . .eP245 Blanco, M.T. . . . . . . . . . . . . . . . . . eP296, eP395 Blanco-Blanco, M.T. . . . . . . . . . . . . eP296, eP395 Blanco-Lobo, P. . . . . . . . . . . . . . . . . . . . . . .O211 Blasi, F.B. . . . . . . . . . . . . . . . . . . . IS096, SY141 Blaskovich, M.A. . . . . . . . . . . . . . . . . . . . .P0293 Blau, D.M. . . . . . . . . . . . . . . . . . . . . . . . . P1315 Blazquez Garrido, R. . . . . . . . . . . . . P1801, P1345 Blazquez Garrido, R.M. . . . . . . . . . . . . . . . .P0941 Blazquez, A.. . . . . . . . . . . . . . . . . .P0513, P0510 Blechova, Z. . . . . . . . . . . . . eP399, eP548, P1340 Blecker-Shelly, D. . . . . . . . . . . . . . . . . . . . P0527 Bleeker-Rovers, C.P. . . . . . . . . . . . . . eP227, P1256 Blennow, O. . . . . . . . . . . . . . . . . . . . . . . . O233 Bleotu, C. . . . . . . . . . . . . . . P0321, P0173, P0389 Blidaru, A. . . . . . . . . . . . . . . . . . . . . . . . .eP029 Bliemer, M.C.J. . . . . . . . . . . . . . . . . . . . . . O224 Blijlevens, N.M.A. . . . . . . . . . . . . . . . . . . . P1692 Blobner, W. . . . . . . . . . . . . . . . . . . . . . . . P0989 Bloemberg, G.V. . . . . . . . . . . P0607, P0916, P1183 Blok, D.C. . . . . . . . . . . . . . . . . . . . . . . . . P0101 Blokhina, E. . . . . . . . . . . . . . . . . . . . . . . P0056 Blomme, S. . . . . . . . . . . . . . . . . . . . . . . . P1772 Blondeau, J. . . . . . . . . . . . . . . . . . . . . . . .eP176 Blot, S. . . . . . . . . . . . . . . . . . . . . . . . . . P0047 Blu, J. . . . . . . . . . . . . . . . . . . . . . . . . . . P0309 Blumberg, N. . . . . . . . . . . . . . . . . .eP059, P0785 Blutraich, N. . . . . . . . . . . . . . . . . . . . . . . . O082 Blyn, L. . . .O219, O262, P0534, P0543, P1427, P1441 Boakes, E. . . . . . . . . . . . . . . . . . . . . . . . .P0194 Boboyianni, C. . . . . . . . . . . . . . . . . P0689, P1279 Bocanegra, C. . . . . . . . . . . . . . . . . . . . . . . O182 Bocconi, A. . . . . . . . . . . . . . . . . . . . . . . . eP265 Böcher, O. . . . . . . . . . . . . . . . . . . . . . . . .P1769 Bochkova, G. . . . . . . . . . . . . . . . . . . . . . .P1401 Bock, L.J. . . . . . . . . . . . . . . . . . . . . O079, P1115 Bockelman, S. . . . . . . . . . . . . . . . . . . . . . P0250 Bodavula, P. . . . . . . . . . . . . . . . . . . . . . . eP056 Boddey, J.A.. . . . . . . . . . . . . . . . . . . . . . . O222 Böddi, K. . . . . . . . . . . . . . . . . . . . . . . . . .eP225 Bodilsen, J. . . . . . . . . . . . . . . . . . . . . . . .P1456 Bodinayake, C.K. . . . . . . . . . . . . . . . . . . . . O230 Bodmer, T. . . . . . . . . . . . . . . P1110, P1372, P1417 Bodoev, I. . . . . . . . . . . . . . . . . . . . . . . . . P0976 Bodro Marimont, M. . . . . . . . . . . . . . . . . . .P1302 Bodro, M. . . . . . . . . . . . . . . . . . . . . . . . . . O110 Bodur, H. . . . . . . . . . . . . . . . . . . . . . . . . P1006 Boelens, J. . . . . . . . . . . . . . eP513, P0732, P1328 Boer de, M. . . . . . . . . . . . . . . . . . . . . . . . .O051 Boermeester, M.A. . . . . . . . . . . . . . . . . . . . O100 Boesl, A. . . . . . . . . . . . . . . . . . . . . P0813, P1376 Boga, J.A. . . . . . . . . . . . . . . . . . . . . . . . . P0630 Bogaards, J.A. . . . . . . . . . . . . . . . . . . . . . .O100 Bogaerts, P. . . . . . . . . . . . . . eP331, eP398, O158, P1051, P1079, P1209, P1648 Bogatyreva, E. . . . . . . . . . . . . . . . . . . . . . O068 Bogdan, C. . . . . . . . . . . . . . . . . . . . . . . . . P0123 Bogdanov, A. . . . . . . . . . . . . . . . . . . . . . . P0124 Bogdanski, R. . . . . . . . . . . . . . . . . . . . . . . O108 Bögelein, M. . . . . . . . . . . . . . . . . . . . . . . . O108 Bognár, C. . . . . . . . . . . . . . . . . . . . . . . . .P0245 Bogni, S.C. . . . . . . . . . . . . . . . . . . . . . . . .P1577 Bogomolova, T. . eP371, eP382, eP386, P0048, P1317 Bogomolova, T.S. . . . . . . . . . . . . . . . . . . . .P0105 Bogovic, P. . . . . . . . . . . . . . . . . . . . . . . . .eP079 Bogusz, A. . . . . . . . . . . . . . . . . . . . . . . . .eP269 Bohlmann, M.K. . . . . . . . . . . . . . . . . . . . . eP555 Bøhn, T. . . . . . . . . . . . . . . . . . . . . . . . . . eP136 Boiron, P. . . . . . . . . . . . . . . . . . . . . . . . . P0609 Boisset, S. . . . . . . . . . . . . . .eP196, P0623, P0765 Boix, V. . . . . . . . . . . . . . . . . . . . . . . . . . . O101 Bojarska, A. . . . . . . . . . . . . . . . . . . . . . . .P1664 Bojarska, K. . . . . . . . . . . . . . . . . . .P0353, P1205 Bojovic, K. . . . . . . . . . . . . . . . . . . . . . . . P0687 256 24th ECCMID / Barcelona Final Programme NameNumber Bojtarova, E. . . . . . . . . . . . . . . . . . . . . . . eP360 Bokesch, P. . . . . . . . . . . . . . . . . . . . . . . . P1702 Bolard, A. . . . . . . . . . . . . . . . . . . . . . . . . P1123 Boldrin, C. . . . . . . . . . . . . . . . . . . . O166, P1895 Boldrin, M. . . . . . . . . . . . . . . . . . . . . . . . . .O071 Bolkhovets, G. . . . . . . . . . . . . . . . . . . . . . P0374 Bollani, L. . . . . . . . . . . . . . . . . . . . . . . . .P1868 Bollheimer, C. . . . . . . . . . . . . . . . . . . . . . .P0134 Bollinger, S. . . . . . . . . . . . . . . . . . . . . . . .P0751 Bolokhovets, G. . . . . . . . . . .P0368, P0369, P0371, P0372, P0373, P0377 Bolton, P. . . . . . . . . . . . . . . . . . . . . . . . . .P0358 Bolukcu, S. . . . . . . . . . . . . . . . . . . eP580, P0418 Bonacorsi, S. . . . . . . . . . . . . . . . . . . . . . .P1856 Bonamini, A. . . . . . . . . . . . . . . . . . . . . . . P0827 Bonastre Mora, J. . . . . . . . . . . . . . . P0391, P1440 Bonato de Souza, L. . . . . . . . . . . . . . . . . . P0034 Bonazzina, R.A. . . . . . . . . . . . . . . . . . . . . P0887 Bondarenko, S. . . . . . . . . . . . . . . . . . . . . . P1317 Bonet Farell, M. . . . . . . . . . . . . . . . . . . . . eP054 Bonet Papell, G. . . . . . . . . . . . . . . . . . . . . eP054 Bonet, B. . . . . . . . . . . . . . . . . . . . . . . . . .eP511 Bonetti, E.J. . . . . . . . . . . . . . . . . . . . . . . . O180 Bonetti, E.-J. . . . . . . . . . . . . . . . . . . . . . . P0355 Bonfanti, P. . . . . . . . . . . . . . . . . . . . . . . . P0339 Bongaerts, M. . . . . . . . . . . . . . . . . . . . . . P0864 Bonkat, G. . . . . . . . . . . . . . . . . . . . .O007, P0581 Bonnell, J. . . . . . . . . . . . . . . . . . . . . . . . . O131 Bonnet, E. . . . . . . . . . . . . . . . . . . . . . . . eP228 Bonnet, G. . . . . . . . . . . . . . . . . . . . . . . . P0398 Bonnet, R. . . . . . . . . . . . . . . . . . . . . . . . .P1032 Bonnet-Pierroz, A. . . . . . . . . . . . . . . . . . . .eP085 Bonney, L. . . . . . . . . . . . . . . . . . . . . . . . . O079 Bonofiglio, R. . . . . . . . . . . . . . . . . . . . . . .P1307 Bonoldi, A. . . . . . . . . . . . . . . . . . . . . . . . P0939 Bonomo, R.A. . . . . . . . . eP606, O191, O253, SY270 Bonten, M. . . . . . .eP493, O114, O157, P0553, P0954 Bonten, M.J.D. . . . . . . . . . . . . . . . . . . . . . P0557 Bonten, M.J.M. . . . . . . eP035, eP062, eP069, O176, O200, O260, P0471, P0550, P1346, P1347, P1350, P1461, SY085, SY299 Bonura, C. . . . . . . . . . . . . . . . . . . . . . . . .P1633 Boon, L. . . . . . . . . . . . . . . . . . . . . . . . . . P0175 Boot, H. . . . . . . . . . . . . . . . . . . . . . . . . . P1385 Boppana, S. . . . . . . . . . . . . . . . . . . . . . . . O148 Bora, A. . . . . . . . . . . . . . . . . . . . . . . . . . P0407 Bo-Ram, K. . . . . . . . . . . . . . . . . . . . . . . . P1550 Borbényi, Z. . . . . . . . . . . . . . . . . . . . . . . .P1280 Borcan, E. . . . . . . . . . . . . . . . . . . . . . . . . P0721 Bordallo Cardona, M.A. . . . . . . . . . . . . . . . .P0021 Bordi, E. . . . . . . . . . . . . . . . . . . . . . . . . . P0882 Bordi, L. . . . . . . . . . . . . . . . . . . . . . . . . . P1940 Bordier, C. . . . . . . . . . . . . . . . . . . . . . . . P0642 Borelli, M. . . . . . . . . . . . . . . . . . . . . . . . . P1814 Borens, O. . . . . . . . . . . . . . . . . . . . . . . . P0098 Borges Dos Santos, S. . . . . . . . . . . . . O223, P1614 Borges, F. . . . . . . . . . . . . . . . . . . . . . . . . P0909 Borgese, L. . . . . . . . . . . . . . . . . . . . . . . . . O212 Borgeson, J.. . . . . . . . . . . . . . . . . . . . . . .P1409 Borghetti, A.. . . . . . . . . . . . . . . . . . . . . . .P1766 Borghi, E. . . . . . . . . . . . . . . . . . . . . . . . . P0007 Borghi, M. . . . . . . . . . . . . . . . . . . P1008, P1196 Borgmann, S. . . . . . . . . . . . . . . . . . . . . . P0989 Borissova, V. . . . . . . . . . . . . . . . . . . . . . . P1143 Börjesson, S. . . . . . . . . . . . . . . . . . . . . . P0209 Bormotov, N. . . . . . . . . . . . . . . . . . . . . . . P0114 Boror, E. . . . . . . . . . . . . . . . . . . . . . . . . .P1881 Borrás Máñez, M. . . . . . . . . . . . . . . eP182, P1378 Borras, M.D. . . . . . . . . . . . . . . . . . . . . . . .P0816 Borrás-Máñez, M. . . . . . . . . . . . . . . . . . . .P1954 Borrell, N. . . . . . . . . . . . . . . . . . . . . . . . . .O250 Borrell, S. . . . . . . . . . . . . . . . . . . . . . . . . SY277 Borrós, S. . . . . . . . . . . . . . . . . . . . . . . . . P0028 Borsboom, G. . . . . . . . . . . . . . . . . . . . . . . O194 Borthagaray, G. . . . . . . . . . . . . . . . . . . . . P1107 Bortolaia, V. . . . . . . . . . . . . . . . . . . P0169, P1465 Bortolin, M.T. . . . . . . . . . . . . . . . . . . . . . .P1909 Borzova, Y. . . . . . . . . . . . . . . . . . . .eP371, P1317 Bosak, I.A. . . . . . . . . . . . . . . . . . . . . . . . .P0105 Bosák, J. . . . . . . . . . . . . . . . . . . . . . . . . .P0144 Bosch, J. . . . . . . . . . . . . . . . P1302, P1527, P1844 Bosch, T. . . . . . . . . . . . . . . . . . . . . . . . . .P1603 Boschiroli, M.L. . . . . . . . . . . . . . . . . . . . . .P0945 Boskani, T.. . . . . . . . . . . . . . . . . . . . . . . .P0358 Bosnar, M. . . . . . . . . . . . . . . . . . . . . . . . .P0143 Bosnjak, Z. . . . . . . . . . . . . . . . . . . . . . . . P1210 Bossard, C. . . . . . . . . . . . . . . . . . . . . . . .P0044 Bosshard, P. . . . . . . . . . . . . . . . . . eP573, P0086 Bosso, J. . . . . . . . . . . . . . . . . . . . . . . . . .eP537 Bostanci, N. . . . . . . . . . . . . . . . . . . . . . . P0607 Boswihi, S. . . . . . . . . . . . . . . . . . . . . . . . P1222 Boszczowski, I. . . . . . . . . . . . . . . . . . . . . .O042 Botelho, A. . . . . . . . . . . . . . . . . . . . . . . . .P0397 Botelho, J. . . . . . . . . . . . . . . . . . . . eP327, eP469 Botelho-Nevers, E.. . . . . . . . . . . . . . . . . . .P0190 Botrugno, R. . . . . . . . . . . . . . . . . . . . . . . P0578 Botterel, F. . . . . . . . . . . . . . . . . . . . . . . . .P0037 Böttger, E.C. . . . . . . . . . . . . . . . . . .P0916, P1183 Bou, G. . . . . . . eP447, eP507, P0178, P0234, P0345 Bouattour, A. . . . . . . . . . . . . . . . . .P0422, P0431 Boubaker, G. . . . . . . . . . . . . . . . . . . . . . . P0640 Boubekri, I. . . . . . . . . . . . . . . . . . . . . . . . eP559 Bouchahrouf, W. . . . . . . . . . . . . . . . . . . . .P1648 Bouchami, O. . . . . . . . . . . . . . . . . . . . . . .P1236 Boucharhouf, W. . . . . . . . . . . . . . . . . . . . .P1051 Boucher, H. . . . eP408, P0193, P1818, P1819, P1820 Bouchiat, C. . . . . . . . . . . . . . . . . . . eP073, O255 Bouchillon, S. . . . . . . .eP437, eP439, P1055, P1068, P1072, P1074, P1078, P1085, P1144, P1202, P1479, P1588, P1593, P1596, P1778, P1781, P1782, P1783 Bouchrik, M. . . . . . . . . . . . . . . . . . . . . . .P0044 Boudewijns, M. . . . . . . . . . . . . . . . . . . . . .eP339 Boufekkane, M. . . . . . . . . . . . . . . . . . . . . eP559 Bougnoux, M.E.. . . . . . . . . . . . . . . P0011, P0066 Bougnoux, M.-E. . . . . . . . . . . . . . . . . . . . P0043 Boukadida, J. . . . . . . . . . . . . . . . . . . . . . P0604 Boukhris, S.A.. . . . . . . . . . . . . . . . . . . . . .P0873 Boulagnon, C. . . . . . . . . . . . . . . . . . . . . . .P0479 Boulo, M. . . . . . . . . . . . . . . . . . . . . . . . . .eP411 Boulos, A. . . . . . . . . . . . . . . . . . . . . . . . . eP219 Boulware, D.R. . . . . . . . . . . . . . . . . . . . . .SY229 Bouman, C.S.C. . . . . . . . . . . . . . . . . . . . . eP009 Bouquié, R. . . . . . . . . . . . . . . . . . . . . . . .P0277 Bourdakis, A. . . . . . . . . . . . . . . . . . . . . . P0409 Bourgeois, M. . . . . . . . . . . . . . . . . . . . . . eP398 Bourgeois-Nicolaos, N. . . . . . . . . . . .P1562, P1558 Bourigault, C. . . . . . . . . . . . . . . . . eP410, eP024, eP112, P0818, P1842 Boussat, S. . . . . . . . . . . . . . . . . . . . . . . . P0376 Bouthry, E. . . . . . . . . . . . . . . . . . . . . . . . P1387 Boutiba, I. . . . . . . . . . . . . . . P1028, P1168, P1635 Boutoille, D. . . .eP410, eP112, P0089, P0100, P0818 Boutolleau, D. . . . . . . . . . . . . . . . . . . . . . .P1309 Bouylout, K. . . . . . . . . . . . . . . . . . . .eP413, O245 Bouza Santiago, E. . . . . . . . . . . . . . . . . . . IS039 Bouza, E. . . . . eP105, eP183, eP198, eP234, eP238, eP245, eP369, eP378, eP385, O090, O189, O220, P0005a, P0012, P0520, P0741 Bouza, M.E. . . . . . . . . . . . . . . . . . . . . . . P0045 Bouzinbi, N. . . . . . . . . . . . . . . . . . . . . . . .P0945 Bowen, A.C. . . . . . . . . . . . . . . . . . . . . . . .eP189 Bowers, D.R. . . . . . . . . . . . . . . . . . . . . . . P1725 Bowker, K. . . . . . . . . . . . . . . . . . . . P0281, P1739 Bowker, K.E. . . . . . . . . . . . . . . . . . . . . . . SY272 Bowyer, P. . . . . . . . . . . . . . . . . . . . . . . . .eP244 Boyd, D.A. . . . . . . . . . . . . . . . . . . . . . . . .eP333 Boye, K. . . . . . . . . . . . . . . . . . . . . . . . . . P1534 Boyer, A. . . . . . . . . . . . . . . . . . . . . O255, P0349 Boyer-Besseyre, M. . . . . . . . . . . . . . . . . . .eP010 Boysen, L. . . . . . . . . . . . . . . . . . . . . . . . .P1647 Bozidis, P. . . . . . . . . . . . . . . . . . . . . . . . .P1854 Bozkurt, F. . . . . . . . . . . . . . . . . . . . . . . . P0699 Bozkurt-Guzel, C. . . . . . . . . . . . . . . . . . . . P0312 Bracco, S. . . . . . . . . . . . . . . . . . . .P0339, P1797 Bradford, T.A. . . . . . . . . . . . . . . . . . . . . . .P0293 Bradley, J. . . . . . . . . . . . . . . . . . . . . . . . .P1702 Braeu, T. . . . . . . . . . . . . . . . . . . . . . . . . .P0763 Bragantini, M. . . . . . . . . . . . . . . . . eP329, eP337 Braggion, C. . . . . . . . . . . . . . . . . . . . . . . .P1537 Braissant, O. . . . . . . . . . . . . . . . . . . . . . . .O007 Brako, L. . . . . . . . . . . . . . . . . . . . . . . . . .eP545 Branco, J. . . . . . . . . . . . . . . . . . . . . . . . .eP253 Brandao, C. . . . . . . . . . . . . . . . . . . . . . . P0563 Brandenburg, A.H. . . . . . . . . . . . . . . . . . . . P1414 Brando, B. . . . . . . . . . . . . . . . . . . . . . . . .P1936 Brandolini, M. . . . . . . . eP125, eP611, P0810, P1289 Brandt, C. . . . . . . . . . . . . . . . . . . . . . . . .P1499 Branger, C. . . . . . . . . . . . . . . . . . . P0487, P1354 Branko Jaglikovski, B. . . . . . . . . . . . . . . . P0395 Brannen, P. . . . . . . . . . . . . . . . . . . . . . . . P1424 Brannigan, E.T. . . . . . . . . . . . . . . . . . . . . . O048 Braquet, P. . . . . . . . . . . . . . . . . . . . . . . . .eP100 Bras, W. . . . . . . . . . . . . . . . . . . . . . . . . . . O176 Braschi, A. . . . . . . . . . . . . . . . . . . . . . . . .P0473 Brassard, P. . . . . . . . . . . . . . . . . . . . . . . . O003 Bratcher, H. . . . . . . . . . . . . . . . . . . . . . . . O031 Bratos, M.A. . . . . . . . . . . . . . . . . . . . . . . P0340 Bratus, E. . . . . . . . . . . . . . . . . . . . . . . . . P1589 Braun, D. . . . . . . . . . . . . . . . . . . . . . . . . . P1913 Braun, E. . . . . . . . . . . . . . . . . . . . . . . . . .P1349 Braun, G. . . . . . . . . . . . . . . . . . . . . . . . . . O076 Braun, N.. . . . . . . . . . . . . . . . . . . . . . . . .eP166 Braun, S. . . . . . . . . . . . . . . . . . . . . . . . . .P1493 Braun, T. . . . . . . . . . . . . . . . . . . . . . . . . .P1001 Bravo Urbieta, J. . . . . . . . . . . . . . . . . . . . .P0941 Braz, V. . . . . . . . . . . . . . . . . . . . . . . . . . .P1459 Brea Aparicio, R. . . . . . . . . . . . . . . . . . . . P0949 Breathnach, A. . . . . . . . . . . . . . . . . O046, P1044 Brebion, A.. . . . . . . . . . . . . . . . . . . . . . . P0469 Bréchet, C. . . . . . . . . . . . . . . . . . . . . . . . P1445 Brecht, M. . . . . . . . . . . . . . . . . . . . . . . . P0049 Breier, A. . . . . . . . . . . . . . . . . . . . . . . . . .eP052 Breier, A.C. . . . . . . . . . . . . . . . . . . . . . . . P1040 Breitler, V. . . . . . . . . . . . . . . . . . . . . . . . .P1159 Brell, A. . . . . . . . . . . . . . . . . . . . . . . . . . P0588 Bremner, J. . . . . . . . . . . . . . . . . . . . . . . .P1425 Brennan, D.C. . . . . . . . . . . . . . . . . . . . . . . .O215 Brennan, G. . . . . . . . . . . . . . . . . . . . . . . . P1616 Brennan, H. . . . . . . . . . . . . . . . . . . . . . . . eP219 Brennecke, J. . . . . . . . . . . . . . . . . . . . . . .P0230 Bresme-Trigo, I.. . . . . . . . . . . . . . . . . . . . .P0413 Bretagne, S. . . . . .eP365, eP375, O218, O231, P0024 Bretones-Miguélez, R. . . . . . . . . . . . . . . . . eP560 Breuer, J. . . . . . . . . . . . . . . eP556, P0447, P1495 24th ECCMID / Barcelona Final Programme 257 Exhibition NameNumber General Information NameNumber Chairs, Speakers & Authors List of Speakers & Authors List of Speakers & Authors NameNumber NameNumber NameNumber Brianese, N. . . . . . . . . . . . . . . . . . . . . . . .P1882 Bridoux, F. . . . . . . . . . . . . . . . . . . . . . . . . P1711 Brink, A. . . . . . . . . . . . . . . . eP224, eP512, P1034 Brink, A.J. . . . . . . . . . . . . . . . . . . . . . . . .P1018 Brinkmann, A. . . . . . . . . . . . . . . . . P1689, P1710 Brisse, S. . . . . . . . . . . . . . . . . . . . P0175, SY157 Brito, C. . . . . . . . . . . . . . . . . . . . . . . . . . P0186 Brito, M.J. . . . . . . . . . . . . . . . . . . . . . . . .eP154 Brivio, A. . . . . . . . . . . . . . . . . . . . . . . . . .P0579 Brnová, J. . . . . . . . . . . . . . . . . . . . . . . . .eP370 Broadhurst, H. . . . . . . . . . . . . . . . . . . . . . P1737 Brocchi, M. . . . . . . . . . . . . . . . . . . . . . . . P0323 Brocco, F. . . . . . . . . . . . . . . . . . . . . . . . . P0348 Brodsky, D. . . . . . . . . . . . . . . . . . . . . . . .P0750 Brodsky, Y. . . . . . . . . . . . . . . . . . . . . . . . eP217 Broeren, M.A.C. . . . . . . . . . . . . . . . . . . . . .P0341 Broliden, K. . . . . . . . . . . . . . . . . . . . . . . . O147 Bromley, M. . . . . . . . . . . . . . . . . . . . . . . .eP244 Bronk, M. . . . . . . . . . . . . . . . . . . . . . . . . P0286 Brookes, P. . . . . . . . . . . . . . . . . . . . . . . . eP468 Brossier, F. . . . . . . . . . . . . . . . . . . . O088, P0359 Brötz-Oesterhelt, H.. . . . . . . . . . . . .P0311, P0331 Brouillet, R. . . . . . . . . . . . . . . . . . . . . . . .P0616 Brouillette, E. . . . . . . . . . . . . . . . . .eP143, P1564 Brouqui, P. . . . . . . . . . . . . . . . . . . . . . . . .P0417 Brouwer, E. . . . . . . . . . . . . . . . . . . . . . . . . O114 Brouwer, M.C. . . . . . . . . . . . . . . . . . O062, P1453 Brovarone, F. . . . . . . . . . . . .eP465, P0354, P1184 Brown, A. . . . . . . . . . . . . . . P1249, P1264, P1495 Brown, A.C. . . . . . . . . . . . . . . . . . . . . . . . eP556 Brown, D. . . . . . . . . . . . . . . . . . . . O005, P1600 Brown, D.F.J. . . . . . . . . . . . . . . . . EW037, EW041 Brown, H. . . . . . . . . . . . . . . . . . . . . . . . . P1103 Brown, N.M. . . . . . . . . . . . . . . . . . . . . . . .P1789 Brown, S. . . . . . . . . . . . . . . . . . . . eP543, P0796 Broyles, D.. . . . . . . . . . . . . . . . . . . . . . . .P1404 Bru, J.P. . . . . . . . . . . . . . . . . . . . . . . . . . P1726 Bruce, K. . . . . . . . . . . . . . . . . . . . . eP494, SY316 Bruce, T. . . . . . . . . . . . . . . . . . . . . . . . . eP086 Bruchfeld, J. . . . . . . . . . . . . . . . . . . . . . . P0956 Bruderer, T. . . . . . . . . . . . . . . . . . . eP109, P1458 Bruggeman, C. . . . . . . . . . . . . . . . .P1586, P1707 Brüggemann, R.J. . . . . . . . . .P1692, P1698, P1700 Brugnaro, P. . . . . . . . . . . . . . . . . . . . . . . P0940 Bruijnesteijn van Coppenraet, L.E.S. . . . . . . .eP094 Bruijnesteijn, L. . . . . . . . . . . . . . . . . . . . . .O051 Bruisten, S. . . . . . . . . . . . . . . . . . .eP488, eP573 Brun-Buisson, C. . . . . . . . . . . P0550, P0557, SY297 Bruneel, A.-S. . . . . . . . . . . . . . . . . . . . . . .P0011 Brunet, M. . . . . . . . . . . . . . . . . . . . . . . . .P1708 Brunetti, E. . . . . . . . . . . . . .P0635, P0636, P0953 Bruni, B. . . . . . . . . . . . . . . . . . . . . . . . . .P1360 Bruni, S. . . . . . . . . . . . . . . . . . . . . . . . . .eP589 Brunkhorst, F.M. . . . . . . . . . . . . . . . . . . . . O108 Bruno, A. . . . . . . . . . . . . . . . . . . . . . . . . P0708 Bruno, R. . . . . . . . . . . . . . . . . . . . . P1289, P1911 Brunschweiler, B. . . . . . . . . . . . . . . . . . . . P1531 Bruyere, R. . . . . . . . . . . . . . . . . . . .eP345, O199 Bryant, K. . . . . . . . . . . . . . . . . . . . . . . . .SY109 Bryers, J. . . . . . . . . . . . . . . . . . . . . . . . . eP135 Bubba, L. . . . . . . . . . . . . . . . . . . . . . . . . P1412 Buchan, B. . . . . . . . . . . . . . . . . . . . O074, P0858 Buchan, B.W. . . . . . . . . . . . . . . . . . . O165, O265 Bucher, M. . . . . . . . . . . . . . . . . . . . . . . . P0386 Buchheidt, D. . . . . . . . eP247, P0051, P0053, P1277 Buchrieser, C. . . . . . . . . . . . . . . . . . . . . . .P1355 Buddhathoki, B. . . . . . . . . . . . . . . . . . . . . P1384 Budding, A.E. . . . . . . . . . . . . eP492, eP498, O096, O100, O203, P1498 Buddy Creech, C.. . . . . . . . . . . . . . . . . . . .eP134 Buechler, J. . . . . . . . . . . . . . . . . . . . . . . .P0625 Bueno, M.F. . . . . . . . . . . . . . . . . . . P1047, P1511 Buer, J. . . . . . . . . . . . . . . . . . . . . .eP236, P0018 Bugert, J. . . . . . . . . . . . . . . . . . . . . . . . . P1173 Bugier, S.. . . . . . . . . . . . . . . . . . . . . . . . .P1204 Bührer, C. . . . . . . . . . . . . . . . . . . . . . . . . eP168 Bui, H.N. . . . . . . . . . . . . . . . . . . . . . . . . . O255 Buising, K.. . . . . . . . . . . . . . . . . . . eP521, P0379 Buiting, A.G. . . . . . . . . . . . . . . . . . . . . . . . P0713 Buiting, A.G.M. . . . . . . . . . . . . . . . . . . . . .P1758 Buke, C. . . . . . . . . . . . . . . . . . . . . eP126, P1623 Bukovski, S. . . . . . . . . . . . . . . . . . .eP018, P0647 Bukovski-Simonoski, S. . . . . . . . . . . . . . . . P0514 Bulanda, M. . . . . . . . . . . . . . . . . . .P0136, P0531 Bulane, A. . . . . . . . . . . . . . . . . . . . . . . . .eP459 Bulbarelli, A. . . . . . . . . . . . . . . . . . . . . . . P1677 Bulgakova, V. . . . . . . . . . . . . . . . . . . . . . .P1244 Bull, A. . . . . . . . . . . . . . . . . . . . . . . . . . .eP233 Bulnes Ramos, Á. . . . . . . . . . . . . . . . . . . . . O107 Bülow, E. . . . . . . . . . . . . . . . . . . . . . . . . .eP493 Bulut, C. . . . . . . . . . . . . . . eP605, P0459, P0460, P1056, P1829, P1956, P1957 Bulut, P. . . . . . . . . . . . . . . . . . . . . . . . . . P0414 Bulychev, L. . . . . . . . . . . . . . . . . . . . . . . . P0114 Bundy, J. . . . . . . . . . . . . . . . . . . . . . . . . P0774 Burckhardt, I. . . . . . . . . . . . . . . . . . eP193, P1510 Burdet, C. . . . . . . . . . . . . . . . . . . . . . . . . P1247 Burdino, E. . . . . . . . . . . . . . . . . . . P1398, P1760 Burger, D.M. . . . . . . . . . . . . . . . . . . . . . . .P1692 Burger, T. . . . . . . . . . . . . . . . . . . . . . . . . .P0529 Burgey, C. . . . . . . . . . . . . . . . . . . . . . . . .P0195 Burggrave, R. . . . . . . . . . . . . . . . . . . . . . . O036 Burgmann, H.. . . . . . eP315, P0090, P0692, P1688 Burgos, J. . . . . . . . . . . . . . . . . . . . . . . . .P1883 Burgos-Teruel, A. . . . . . . . . . . . . . . . . . . . .P1954 Burillo, A. . . . . . . . . . . . . . . . . . . . eP150, eP198 Burioni, R. . . . . . . . . . . . . . . . . . . . . . . . .P0541 Burkov, A. . . . . . . . . . . . . . . P1397, P1401, P1926 Burns, C.C.. . . . . . . . . . . . . . . . . . . . . . . P0446 Burns, K. . . . . . . . . . . . . . . . . . . . . . . . . .P0788 Burr, S. . . . . . . . . . . . . . . . . . . . . . . . . . .P1847 Burrel, S. . . . . . . . . . . . . . . . . . . . . . . . . .P1309 Burucoa, C. . . . . . . . . . . . . . . . . . . . . . . .eP043 Busca, A. . . . . . . . . . . . . . . . . . . . . . . . . .P1266 Buscaglia, G. . . . . . . . . . . . . . . . . . . . . . . eP609 Buser, A. . . . . . . . . . . . . . . . . . . . . . . . . .P1403 Busi-Rizzi, E. . . . . . . . . . . . . . . . . . . . . . .P0641 Busquets Casals, D. . . . . . . . . . . . . . . . . . eP496 Busse, A. . . . . . . . . . . . . . . . . . . . . . . . . .eP156 Bustinduy, M.J. . . . . . . . . . . . . . . . . . . . . eP569 Bustos, C. . . . . . . . . . . . . . . . . . . . . . . . P1944 Butcher, P.D. . . . . . . . . . . . . . . . . . . . . . . P1754 Butel, M.J. . . . . . . . . . . . . . . . . . . . . . . . .P1562 Butic, I. . . . . . . . . . . . . . . . . . . . . . . . . . .eP018 Butin, M. . . . . . . . . . . . . . . . . . . . . . . . . . O207 Butler, A. . . . . . . . . . . . . . . . . . . . . . . . . .P0347 Butler, D.L. . . . . . . . . . . . . . . . . . . . . . . . P1666 Butler-Wu, S.M. . . . . . . . . . . . . . . . . . . . . .P1794 Buttinelli, G. . . . . . . . . . . . . . . . . . . . . . . .P1546 Büttner, H.. . . . . . . . . . . . . . . . . . . . . . . .eP292 Buttrini, M. . . . . . . . . . . . . . . . . . .eP480, P0669 Buyck, J.M. . . . . . . . . . . . . . . . . . . P0174, P1077 Buyle, F. . . . . . . . . . . . . . . . . . . . . . . . . . eP513 Büyük, A. . . . . . . . . . . . . . . . . . . . . . . . . P0214 Buyuk, Y. . . . . . . . . . . . . . . . . . . . . . . . . . P1374 Buzelé, R. . . . . . . . . . . . . . . . . . . . eP432, P1672 Buzina, W. . . . . . . . . . . . . . eP243, eP393, P0053 Bwanga, F. . . . . . . . . . . . . . . . . . . . . . . . .P0919 Byl, B. . . . . . . . . . . . . . . . . . . . . . . . . . . P0575 Byotra, S.P. . . . . . . . . . . . . . . . . . . . . . . . P0656 Bystricks, S. . . . . . . . . . . . . . . . . . . . . . . P1255 Bystricky, S. . . . . . . . . . . . . . . . . . . . . . . P1246 Byun, J.W. . . . . . . . . . . . . . . . . . . . . . . . .P0790 Bzekalava, N. . . . . . . . . . . . . . . . . . . . . . . O086 C Ca, B. . . . . . . . . . . . . . . . . . . . . . . . . . . P0401 Caballero Pérez, J. . . . . . . . . . . . . . . . . . . .P1286 Caballero, J.D. . . . . . . . . . . . . . . . . eP500, P1552 Caballero-Moyano, F.J. . . . . . . . . . . . . . . . P0228 Cabanes, D. . . . . . . . . . . . . . . . . . . . . . . .P0186 Cabellos Minguez, M. . . . . . . . . . . . . . . . . .P1457 Cabellos, C. . . . . . . . . . . . . .eP039, P0095, P1454 Cabero, L. . . . . . . . . . . . . . . . . . . . . . . . .P1380 Cabeza Brasa, M.C. . . . . . . . . . . . . . . . . . . .O046 Cabie, A. . . . . . . . . . . . . . . . . . . . . . . . . . eP121 Cabo-Magadán, R. . . . . . . . . . . . . . . . . . . P0968 Cabral Dias, C. . . . . . . . . . . . . . . . . . . . . . P1203 Cabral, L.. . . . . . . . . . . . . . . . . . . . . . . . P0064 Cabral, L.g. . . . . . . . . . . . . . . . . . . . . . . . P1738 Cabrera, G.. . . . . . . . . . . . . . . . . . . . . . . P0892 Caccio, S. . . . . . . . . . . . . . . . . . . . . . . . .EW078 Cacciò, S.M. . . . . . . . . . . . . . . . . . . . . . . P0644 Cacciotti, G. . . . . . . . . . . . . . . . . . . . . . . .P0160 Caceda, B. . . . . . . . . . . . . . . . . . . . . . . . .P1525 Cachafeiro, L. . . . . . . . . . . . . . . . . . . . . . .P1695 Caciagli, P. . . . . . . . . . . . . . . . . . . . . . . . .eP297 Caetano, M. . . . . . . . . . . . . . . . . . . . . . . P0064 Cag, Y. . . . . . . . . . . .P0408, P0999, P1606, P1630 Caglioti, C. . . . . . . . . . . . . . . . . . . . . . . . .P1940 Cagnin, D. . . . . . . . . . . . . . . . . . . . . . . . .P1936 Cahill, O. . . . . . . . . . . . . . . . . . . . . . . . . .eP264 Cai, T. . . . . . . . . . . . . . . . . . . . . . . . . . . .eP297 Cai, Y. . . . . . . . . . . . . . . . . . . . . . . . . . . eP004 Caiaffa Filho, H. . . . . . . . . . . . . . . . . . . . . P1297 Caierão, J. . . . . . . . . . . . . . . . . . . . . . . . . P1519 Caillard, S. . . . . . . . . . . . . . . . . . . . . . . . .P1407 Caillon, J. . . . . . . . . .eP024, eP112, P0089, P0100, P0818, P1058, P1526, P1842 Caillot, D. . . . . . . . . . . . . . . . . . . . . . . . . eP364 Caione, M.D. . . . . . . . . . . . . . . . . . .P1428, P1546 Caira, M. . . . . . . . . . . . . . . . . . . . . . . . . .P1266 Cairns, M. . . . . . . . . . . . . . . . . . . . .O004, P0791 Cajic, V. . . . . . . . . . . . . . . . . . . . . . . . . . .P1953 Cakir, N. . . . . . . . . . . . . . . . . . . . . . . . . . eP107 Calandra, T. . . . . . . . . . . . . . . . . . . . . . . .SY084 Calbo, E. . . . . . . . . . . . . . . . . . . . .eP552, eP553 Calderaro, A. . . . . . . . .eP477, eP478, eP480, O184, O267, P0669, P1429, P1430 Calderón González, R. . . . . . . . . . . . . . . . . P0187 Calderón, E. . . . . . . . . . . . . . . . . . . . . . . .P1626 Calé, S. . . . . . . . . . . . . . . . . . . . . . . . . . .eP312 Calero, M.L. . . . . . . . . . . . . . . . . . . . . . . .P1626 Calia, C.. . . . . . . . . . . . . . . . . . . . P0838, P0875 Caliandro, R. . . . . . . . . . . . . . . . . . . . . . . P0967 Calil, J. . . . . . . . . . . . . . . . . . . . . . . . . . . P1017 Calina, D.. . . . . . . . . . . . . . . . . . . . . . . . .P1026 Calistru, P.I. . . . . . . . . . . . . . . . . . . . . . . .P1950 Calitri, C. . . . . . . . . . . . . . . . . . . . . . . . . .P1863 Callan, A. . . . . . . . . . . . . . . . . . . . . .O012, P1165 Calleja Serrano, I. . . . . . . . . . . . . . . . . . . . P1440 Callens, S. . . . . . . . . . . . . . . . . . . . . . . . .eP513 Calleri, M. . . . . . . . . . . . . . . . . . . . P0682, P1894 Calò Carducci, F.I. . . . . . . . . . .O202, P1850, P1851 Calvet, C.M. . . . . . . . . . . . . . . . . . . . . . . P0685 Calvet, X.. . . . . . . . . . . . . . . . . . . . . . . . EW024 Calvo Montes, J. . . . . . . . . . . . . . . . . . . . . P1014 Calvo, J. . . . . . . . . . . . . . . . . . . . . eP447, P1800 258 24th ECCMID / Barcelona Final Programme NameNumber Calzas, I. . . . . . . . . . . . . . . . . . . . . eP571, P1908 Camacho, A. . . . . . . . . . . . . . . . . . . . . . . .eP131 Cámara, J. . . . . . . . . . . . . . . . . . . .P1520, P1659 Camara, M. . . . . . . . . . . . . . . . . . . . . . . . P0172 Camara, M.M. . . . . . . . . . . . . . . . . . . . . . . O131 Camarena, J. . . . . . . . . . . . . . . . . . . . . . .eP511 Camargo, I.L.B.C. . . . . . . . . . . . . . . . . . . . .P1577 Camassa, S. . . . . . . . . . . . . . . . . . . . . . . .P0155 Cambau, E. . . . . . . . . . eP231, EW012, O088, O183, P0359, P0974, P0977, P0978, SY284 Cambieri, P. . . . . . . . . . . . . . . . . . . . . . . .P0810 Cambrea, S. . . . . . . . . . . . . . . . . . . . . . . .P1902 Camcioglu, Y. . . . . . . . . . . . . . . . . . . . . . P0467 Cameron-Veas, K. . . . . . . . . . . . . . . . . . . . P1642 Camilli, R. . . . . . . . . . . . . . . . . . . . . . . . . .O175 Caminero, J.A. . . . . . . . . . . . . . . . . . . . . . P0892 Camino Ortiz de Barron, X.. . . . . . . . . . . . . .eP569 Camoez, M. . . . . . . . . . . . . .P0525, P1486, P1659 Camon, S. . . . . . . . . . . . . . . . . . . . . . . . .P1886 Campa, S. . . . . . . . . . . . . . . . . . . . . . . . P0562 Campainha, R. . . . . . . . . . . . . . . . . . . . . . P1021 Campana, S. . . . . . . . . . . . . . . . . . . . . . . P1537 Campanini, G.. . . . . . . . . . . . . . . . . O225, P0462 Campano, E. . . . . . . . . . . . . . . . . . . . . . . P1626 Campany Herrero, D. . . . . . . . . . . . . . . . . .eP372 Campese, C.. . . . . . . . . . . . . . . . . . . . . . .P1363 Campillo, N. . . . . . . . . . . . . . . . . . . P1694, P1727 Campins, A. . . . . . . . . . . . . . . . . . . . . . . .P0261 Campins, M. . . . . . . . . . . . . . . . . . . P1271, P1380 Campisi, D. . . . . . . . . . . . . . . . . . . . . . . . P1399 Camporese, D. . . . . . . . . . . . . . . . . . . . . P0642 Campos Gutierrez, S. . . . . . . . . . . . . . . . . P0908 Campos Juanatey, F. . . . . . . . . . . . . . . . . .P1258 Campos, I. . . . . . . . . . . . . . . . . . . . . . . . .P1386 Campos, J. . . . . . . . . eP285, eP327, P0846, P1146 Campos-Herrero, M.I. . . . . . . . . . . . . . . . . P0892 Camps, J. . . . . . . . . . . . . . . . . . . . . . . . . P0132 Can, F. . . . . . . . . . . . . . . . . . . . . .P0996, P1049 Can, H. . . . . . . . . . . . . . . . . eP140, P0671, P0691 Canale, F.. . . . . . . . . . . . . . . . . . . . . . . . . P0137 Canarelli, B. . . . . . . . . . . . . . . . . . . . . . . .P1531 Cañas, A.. . . . . . . . . . . . . . . . . . . . . . . . .P1386 Candel Perez, C. . . . . . . . . . . P0941, P1345, P1801 Candoni, A. . . . . . . . . . . . . . . . . . . . . . . . P1266 Canela, B. . . . . . . . . . . . . . . . . . . P0679, P0680 Caner, A. . . . . . . . . . . . . . . . eP140, P0671, P0691 Canestri, A. . . . . . . . . . . . . . . . . . . . . . . . P1631 Caniça, M. . . . . . . . . . . . . . . . . . . . P1007, P1022 Canino, R. . . . . . . . . . . . . . . . . . . . . . . . . P1618 Cannon, C. . . . . . . . . . . . . . . . . . . . . . . . .eP427 Cano García, M.E. . . . . . . . . . . . . . . . . . . . P1014 Cano, E. . . . . . . . . . . . . . . . . . . . . . . . . . . O241 Cano, J. . . . . . . . . . . . . . . . . . . . . . . . . . P1463 Cano, M.A. . . . . . . . . . . . . . . . . . . . . . . . P0995 Canpolat, G. . . . . . . . . . . . . . . . . . . . . . . .P0459 Cantalloube, C. . . . . . . . . . . . . . . . . . . . . .P1690 Canton Moreno, R. . . . . EW038, IS065, SY159, P0021 Canton, R. . . . P0005, P1009, P1239, P1240, P1241, eP340, eP378, eP447, eP448, eP597, P0164, P0222, P0223, P0227, P0381, P1155, P1157, P1161, P1286, P1408, P1552 Canut, A. . . . . . . . . . . . . . . . . . . . . . . . . .P1744 Caola, I.. . . . . . . . . . . . . . . . . . . . . . . . . .eP297 Capatti, C. . . . . . . . . . . . . . . . . . . . . . . . .P1184 Capdevila, J. . . . . . . . . . . . . . . . . . . . . . . P0520 Capobianchi, M.R. . . . . . . . . . . . . . .P1402, P1940 Capolongo, C. . . . . . . . . . . . . . . . . P0838, P0875 Capon, A.. . . . . . . . . . . . . . . . . . . . . . . . .P1918 Caporali, M. . . . . . . . . . . . . . . . . . . . . . . P1808 Cappon, A. . . . . . . . . . . . . . . . . . . . . . . . .P1911 Capretti, M.G. . . . . . . . . . . . . . . . . . . . . . . P1871 Capua, I. . . . . . . . . . . . . . . . . . . . . . . . . .KL219 Car, J. . . . . . . . . . . . . . . . . . . . . . . . . . . . O056 Caraballo, M. . . . . . . . . . . . . . . . . . . . . . . P0573 Carabarin-Lima, A. . . . . . . . . . . . . . . . . . . .eP138 Carannante, A. . . . . . . . . . . . . . . . . . . . . .P1807 Carapetis, J.. . . . . . . . .