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Appendicitis Epidemiology Incidence – 10% lifetime risk, with a peak incidence in the teen’s and 20’s Children less than 7 years old account for less than 3% of cases but nearly 35% of all mortalities. Men:women – 2:1 until the age of 25 and then it evens out Anatomy The appendix is generally is a postero-medial position in relation to the caecum, is approximately 6cm long and the surface point is McBurney’s point (1/3 of the way from the ASIS to the umbilicus). The base of the appendix is located at the point of convergence of the tinea coli. It’s supplied by the appendicular artery – a branch of the posterior caecal artery. 65% are retrocaecal, 30% are pelvic and the rest are pre or post ileal When is the appendix not in the RIF? – in pregnancy, when it’s a long appendix, in cases of maldescent of the caecum and in situs inversus Pathology The mechanism of inflammation is due to obstruction. In younger patients this is generally due to lymphoid hyperplasia, while in older patients it’s usually due to a faecolith. Increased intraluminal pressure leads to lymphatic congestion, venous congestion and finally arterial compression – this will, if untreated, lead to perforation Presentation Symptoms: - Initial periumbilical referred pain, moving to RIF – up to 25% will have no periumbilical pain Anorexia Nausea and minimal vomiting Low grade pyrexia If pelvic – diarrhoea (not profuse), nausea, vomiting and more diffuse pain If the inflamed tip is lying against the bladder, there may be urinary symptoms On Examination: - Rigidity - Tenderness - Guarding - Rebound - Mass - Scars - Roving’s sign - DRE - Psoas sign – pain on active flexion of the hip - Obturator sign – flex hip to 90o – pain on internal rotation - Sore throat – in kids may preceed mesenteric adenitis - Cachexia, organomegaly – neoplasm Atypical presentations can occur in elderly patients or diabetics who may have autonomic neurophaties, those on steroids may have masked symptoms, and in pregnancy – the appendix is high up on the right side and may be moved away from the peritoneum, eliminating the sharp somatic localising sign Investigations - Urinalysis FBC – raised WCC, anaemia CRP U&E HCG in women Rarely may do erect CXR – air under diaphragm? U/S – useful in small children and in young women to rule out gynaecological pathology CT – very accurate but a big radiation dose and time consuming – may do in a patient with an atypical presentation Treatment - NPO IV fluids – NS or Hartmann’s Analgesia Anti-emetics Prophylactic antibiotics – 3rd generation cephalosporin and metronidazole – pre-op antibiotics are given at induction of anaesthesia - DVT prophylaxis NG if vomiting is severe May need a urinary catheter Post-op antibiotics – If the surgery was uncomplicated, two more doses is sufficient. If there was perforation, 5 days of antibiotics Surgery May be open or laparascopic (make sure you drain the bladder) – open can be by a gridiron incision or a lanz incision Layers – skin, subcutaneous fat, Camper’s fascia, Scarper’s fascia, Ext. oblique, Int. oblique, transverse oblique, transversalis fascia, peritoneum Consent - Haemorrhage Anaesthetic risks Conversion to open procedure if patient is being consented for laporoscopy Wound infection Intra-abdominal infection Visceral damage Fistula Abscess Hernia – incisional and indirect inguinal – the ilio-inguinal nerve may be severed during surgery. This innervates the posterior wall of the inguinal canal and damage to the nerve will increase risk of indirect inguinal hernia Adhesions The appendix may be found to be normal Alternate pathology may be found that requires treatment Keloid/hypertrophic scars