Download Chapter 11: Cell cycle - You need to know the definition for the terms

Chapter 11: Cell cycle
- You need to know the definition for the terms listed below. Also you need to be
able to give an example for each term.
Cell cycle
Cell division
Sperm and Egg cell
Somatic cells/Gametes
Sister Chromatids
Centromere
Mitosis
Cytokinesis
Kinetochore
Metaphase plate
Cleavage Furrow
Cell plate
G0 phase
P53
Apoptosis/Programmed cell death
Mitosis Promoting Factor=MPF
Transformation
Benign tumor
Malignant tumor
Metastasis
- What is Chromosome replication? Which phase of the cell cycle it happens?
- Draw a chromosome and label all the parts.
- What are the stages of Cell cycle? What happens in each stage? Be complete.
- What are the phases of mitosis? What happens in each phase? Be complete.
- What is mitotic spindle? What is its function?
- Polar microtubule? Function?
- Kinetochore microtubule? Function?
- The microtubules shorten by depolymerizing at their kinetochore ends
- What was the experiment showed that microtubules shorten at the kinetochore
end?
- Binary fission in Bacteria?
- Cancer cells manage to escape the usual controls on the cell cycle
- Evidence for Cytoplasmic Signals to start a new phase of the cell cycle. Explain the
experiment completely.
- Explain and name all the cell cycle control systems?
-What are cell cycle Check points? Name? Stage of the cell cycle? Function?
- The p53 protein either pauses the cell cycle or initiates apoptosis – programmed
cell death – if the DNA is physically damaged. p53 is an example of a tumor
suppressor; damage to the p53 gene can lead to uncontrolled cell division
- Cyclins and Cyclin-Dependent Kinases? Function? Pattern?
- Some external signals are growth factors, proteins released by certain cells that
stimulate other cells to divide.
- What is Density dependent inhibition?
- What is anchorage dependent?
- Cancer cells exhibit neither density-dependent inhibition nor anchorage
dependence
- Loss of Cell Cycle Controls in Cancer Cells
- Cancer cells:
– They may make their own growth factor
– They may convey a growth factor’s signal without the presence of the
growth factor
– They may have an abnormal cell cycle control system
Be able to draw a cell going through different phases of the cell cycle and label each.
Be able to draw a chromosome with all details of it.
Be able to complete a figure showing different phases of the cell cycle.