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УДК 575.85.856: 636.064.6 HISTOGENESIS IN THE CONTEXT OF THE BODY ONTOGENETIC DEVELOPMENT V.V. SEMCHENKO, Doctor of Medicine, professor L.P.TELTSOV, Doctor of Veterinary Science, Professor G.A.HONIN, Doctor of Veterinary Science, Professor S.S.STEPANOV, Doctor of Medicine A.A.MAKSIMOVSKAYA, aspirant* S.F.MELESHKOV, Doctor of Veterinary Science, Professor S.I.SHVEDOV, Doctor of Veterinary Science, Professor of the Institute of Veterinary Medicine and Biotechnology Omsk State Agrarian University. P.A.Stolypina, All-Russian Research Institute of brucellosis and tuberculosis animals RAAS, Mordovia State University N.P.Ogarev Based on the analysis of long-term results of their own research and literature in terms of the modern paradigm of studying morphological and functional status in the individual development of animals and humans, it is concluded that one of the most rapidly developing areas is a comparative study of the characteristics and changes differon and gistion tissue organization with the concept provisionally histoand morphogenesis, which allows you to position the evidence of biology and medicine with a high degree of reliability to understand laws repair damaged organs in animals and humans, to assess the role of all components differons during reparative regeneration and use these as a basis for the development of gene, cell and tissue technologies of regenerative biology and medicine. Morphology, histology, methodology, tissue histogenesis, ontogeny, differons, regeneration. Partial differons reparative regeneration in the nervous tissue is performed on a background dysfunction and elimination of a large number of neurons, which is a functional imperative for the activation of mechanisms of compensatory reorganization of interneuronal relationships of preserved neural networks. Thus there is a kind of temporary return to developmentally earlier type of neural networks (high concentration of immature presynapses) and the appearance of provisional (hypertrophied) synapses with high potential for transformation into a more complex and effective synaptic device. The study of reparative histogenesis allows to obtain and interpret new knowledge, which are essential for the development of methods of regenerative medicine in veterinary medicine. In this regard, one of the most rapidly developing areas is a comparative study of the changes of differon and gistion organization of various body tissues of animals and humans according to the concept of provisional morphogenesis. Accumulated knowledge allow us to understand the laws of regeneration of damaged organs of animals and humans, to assess the role of all differon’s components(including stem cells) in the process of regeneration and are the basis of development of genetic, cell and tissue regenerative technologies in biology and medicine.