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SCHOOL INFORMATIONS PRATIQUES BIOLOGIE, MÉDECINE, PHARMACIE MASTER Biologie Santé LOCATION Orsay Biologie Santé Université Paris Sud campus. Institut Curie CONTACTS Secretary • Mme Anh Do, 01 69 15 46 44 PARCOURS : Biologie cellulaire et développement / Gene Cell Development (GCD) Responsibles • Pr. Anne-Hélène MONSORO-BURQ, [email protected] • Dr. Isabelle GUENAL, [email protected] MY NOT ES... The recent advances in cell and developmental biology (including imaging, stem cell biology and systems biology) integrate biological mechanisms at multiple scales, from the level of molecular complexes to the whole organism. These fundamental discoveries will have significant therapeutic benefits, notably in cancer biology and regenerative medicine. The “Gene, Cell, and Development” (GCD) Master course explores molecular, genetic and epigenetic mechanisms from cell to organism. This training provides the concepts and methods to understand the variety of processes controlling cell biology during development, differentiation, and disease. ris-saclay.fr rsite-pa www.unive Partenaires Université Paris-Saclay Conception graphique : Université Paris-Sud - Décembre 2014 PREREQUISITES Access to GCD Course implies mastering the theoretical and methodological knowledge of the first year of masters in the following subjects: cell biology, developmental biology, and genetics. This knowledge may have been acquired by various combinations of the courses (called Teaching Units, or UE) proposed in the teaching Platforms called ‘major’ during first year of Master. The Majors “Platforms” recommended are “Molecular and Cell Biology” or “Physiology and Physiopathology”. We also strongly recommend that candidates follow the internship Teaching Unit. OBJECTIVES RESEARCH The “Gene, Cell, and Development” Master course is an advanced course on cell biology during development, differentiation, and disease. A series of lectures, practical courses and personal research will enable the students to understand the recent developments and the current challenges of research around those themes. Science and medical students will thus acquire theoretical knowledge and practical skills essential for them to understand the research topics of their future host laboratories, wherever they will pursue academic, applied or clinical research. The students following the GCD master will work for six months in a host research laboratory, to develop a personal research project, under the close supervision of a mentor. This project will be prepared beforehand, during a specific Teaching Unit, to explore the litterature of the proposed subject and to prepare the outline of the final scientific report. At the end of the research, a written manuscript and and oral presentation (in French or English) will be evaluated by the master committee. In addition to being an immersion into laboratory research, this training potentially sets the basis for a longer Ph.D. project. PERSPECTIVES The main job prospects after this second year of masters will be in fundamental and applied research in France or abroad. This can be achieved mostly by pursuing a Ph.D. thesis, but a few engineer level positions are open after a master thesis. Positions will be found in major academic research institutes, affiliated to University, CNRS, INSERM, INRA, or CEA. The Ph.D. thesis will open the path to an academic research career. Aside academia, other job openings will be found in private companies, as this master degree provides background to become project manager in research and development, clinical research investigator or research engineer. This training is also recommended for clinicians and medical students willing to acquire a fundamental knowledge in cell and developmental biology and pursue clinical research. CONTENTS • Genetics and Cell biology of Development • Non-coding RNAsand Epigenetics • International Curie Paris-Sud Course • Bibliographical Research Project • Scientific Project • Cell Dynamics & Communication • Bioimaging • Neural development & STEM Cells ASSOCIATE LABORATORIES I2BC (Institut de Biologie Intégrative de la Cellule), Institut Curie, IPS2 (Institut of Plant Sciences Paris-Saclay), IDEEV, NeuroPSI, I2C, Handicap Neuromusculaire, Laboratoire Gamète, Implantation, Gestation, Laboratoire de Génétique et Biologie Cellulaire, Institut Micalis, Biologie du Développement et Reproduction, Génétique Animale et Biologie Intégrative, Institut des cellules souches pour le traitement et l’étude des maladies monogéniques, Centre National de Génotypage, Genoscope, Généthon, AFM-Téléthon, Laboratoire de Recherche Européen pour la Polyarthrite rhumatoïde (GenHotel), Laboratoires de Biologie de la Genopole d’Evry, Laboratoire de biologie et de pharmacologie appliquée, Institut Gustave Roussy