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Republic of Iraq Ministry of higher education And Scientific Research University Of Al-Qadisya Collage of Veterinary Medicine A research submitted to Veterinary Medicine College / Al-Qadisiya University, It's partial of fulfillment to get B.Sc.in medical and surgery Of Vet. Med. By Karar Mythem Supervised by Asst.L. Dr.Aoula Emad AL- Zebeedy 2015 A.D. 1436 A.H. The main properties of cancer cell Summery This study was designed to view the definition of tumor cell or neoplasia as a uncontrolled cell division lead to an abnormal mass. The cause of neoplasia physical, chemical, biological and hormonal causes. Explain the important properties of cancer cell then explain the carcinogenesis process by which normal cells are transformed into cancer cells by mutations in DNA that lead to cancer this occur by three steps initiation, promoter and progression . In molecular bases of cancer cell, Cancer is linked to harmful genetic alteration of cells and many genes have been linked to various forms of cancer, but the genetics of cancer is very complicated and less well understood than classic genetics. An oncogene is a gene than, when mutated or expressed at high levels, turn a normal cell into a tumor cell. Tumor suppressor genes are "anti-oncogenes" inhibiting cellular proliferation; they are usually inactivated by loss-of function mutation, in cancer development. The P 53 gene is known to be the most important gene involved in all cancer. The final class of gene implicated in carcinogenesis is involved in the various DNA repair mechanisms that allow accurate DNA repair. One strategy tumors used to acquire apoptosis resistance is the over expression of anti apoptotic molecules like the antiapoptotic proteins Fas Ligand inhibitory protein. Uncontrolled proliferation is a hallmark of cancer cells, molecular analysis of human tumors and animals have provided a clear basis for the understanding of the cellular process that govern cell cycle progression in normal and tumor cells. And finally we explained cancer immunity is referred to interaction between the immune system and cancer cells, it is also a growing field of researches that aims to discover innovative cancer immunotherapies to treat and retard progression of this.