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Basic Animal Biology 2013/2014 Course Manual Teaching L1 Introduction L2 Homeostasis Suggested Reading Unit 1. Homeostasis and Circulatory System. Chapter 1, parts 1.1, 1.2, 1.3 VHP Chapter 1, parts 1.6, 1.7, 1.8 TE1 Homeostasis P1 Birth and Development Chapter 1, parts 1.4 and 1.5 Practicals Manual Chapter 12, Sections A, B, C and D L3 Circulation part 1 (Structure & Function) L4 Circulation part 2 (Heart & Regulation) TE2 Circulation Focus pages: 355, 359-62 356-57, 379, 381, 389-90 362-63, 368-69 372-73, 375, 398, 400 Learning Objectives Calendar week 47. To understand the format and teaching methods of the BAB Course To understand the meaning of the term “physiology” To understand the basic structural organization of the body; cells, tissues, organs, organ systems To understand how homeostasis is achieved To understand how feedback systems operate To understand the set point principle, adaptation and acclimatization and biological rhythms To experience interaction with unfamiliar animals To understand the principle of homeostasis To understand how different species adapt to life’s challenges To recognize the basic anatomy of the heart and blood vessels To understand the basic functions of the cardiovascular system To understand the divisions of the cardiac cycle and how it is regulated To understand the factors that affect blood pressure, and its regulation Key Terms VHP page 18 VHP page 18 Precocious Altricial VHP pages: 358 376 396 404 Teaching L5 Cells Suggested Reading Learning Objectives Unit 2. Fluid Balance and Renal System. Calendar week 48. To understand the basic structure of cells and VHP Chapter 3. This should be revision. Chapter 3 is NOT included in the BAB pensum. Focus on sections A and E L6 Membrane transport VHP Chapter 4. VHP Chapter 6 Section B TE3 Cells and membranes P2 Blood pressure, ECG, cell water VHP Chapter 12 (revision from Unit 1). Practicals Manual L7 Blood, part 1 VHP Chapter 12, section F, partsF.1 and F.2 (Part F.3 haemostasis will be covered later, in TE4) L8 Kidney function, part 1 VHP Chapter 14 L9 Kidney function, part 2 TE4 Fluid balance, including haemostasis VHP Chapter 12, section F, part F.3 cell organelles To understand the basic metabolic functioning of cells To understand the basic structure of cell membranes To understand how molecules move across cell membranes through: Diffusion, facilitated and active transport. Understand the maintenance and regulation of the membrane potential To reinforce knowledge of function of circulatory system and its coordination with water balance Key Terms VHP page 56, 92 VHP page 115116 VHP page To understand the constituents of blood: Plasma (and how plasma differs from serum) The concept of osmosis The importance of the plasma and the extracellular phase for cell function Erythrocytes (red blood cells) Leucocytes (white blood cells) To understand the basic anatomy of the kidneys and urinary system To understand the basic function of the kidney, filtration, reabsorption and secretion. To understand the regulation of kidney function, with focus on water, sodium and potassium. To understand the importance of the kidney for overall salt and water homeostasis and for regulation of blood pressure. VHP page 429 To reinforce knowledge of the different mechanisms contributing to fluid balance in the body VHP page 429 VHP pages 489, 506, 511 Teaching Suggested Reading Learning Objectives Unit 3. Respiratory System and Immune System. L10 Respiration part 1 L11 Respiration part 2 TE4 Respiration P3 Respiration L12 Immune system part 1 L13 TE5 Immune system part 2 Immune system Immune system Demo Circulation research Chapter 13 Focus pages: 435-37 438-42 438, 442, 444, 447 448-52 454-58 460-64 Practicals Manual VHP Chapter 18.1 to 18.4 Practicals Manual Key Terms Calendar week 49. To recognize the distinction between cellular respiration and pulmonary physiology To understand the basic anatomy of the respiratory system To understand the basic functions of the respiratory (or pulmonary) system To understand how gas exchange occurs To understand the transport of gases in the blood To understand the basic principles for regulation of ventilation To reinforce the understanding of ventilation and its regulation, and gaseous exchange To understand the different body systems and cells that contribute to defence against disease. To understand the innate immune response. To understand the inflammatory response. To understand the acquired immune response To experience how a research laboratory works To reinforce knowledge of the circulation VHP page 471 to 472 VHP pages 667-668 Teaching L14 Nervous system part 1 Reading Unit 4. Regulatory Systems. VHP Chapter 6 sections A, C and D (revise section B from unit 2) L15 Nervous system part 2 VHP Chapter 10 TE6 Nervous system L16 Musculo-skeletal system and muscle function VHP Chapter 9 section A Nerves and muscle Practicals Manual P4 L17 Endocrine systems part 1 VHP Chapter 5, section on receptors (this should be revision and is not pensum) VHP Chapter 11 sections A and B L18 TE7 Endocrine systems part 2 Endocrinology VHP Chapter 11 section E Learning Objectives Calendar week 50. To understand the basic anatomy and structure of nerve cells (neurons) and supporting (glial) cells To understand the physioligcal functioning of neurons To understand the generation and propagation of nerve impulses (action potentials) To understand the way in which neurons signal to each other through synapses To understand the structural organisation of the nervous system To understand the interaction between nerves and muscles in the regulation of local motor activity To understand the involvement of higher brain centres in coordinated motor activity To understand the basic anatomy and structure of skeletal, cardiac and smooth muscle To understand the physiological functioning of skeletal muscle To understand skeletal muscle contraction and its regulation at single fibre and whole muscle levels To reinforce knowledge of the integrated actions of the nervous and musculoskeletal systems To understand the different ways in which cells, tissues and organs communicate with each other To understand the location and role of the major endocrine organs To understand the role of the hypothalamus as a regulator of other endocrine systems To understand relationships between the hypothalamus and the pituitary gland To understand the GH and IGF axis and its role in regulating growth To understand the regulation of bone growth and its importance in determining adult size Key Terms VHP pages 141, 156, 169 VHP pages 183, 308 VHP p 278 VHP pages 329, and 336 VHP page 344 Teaching L19 Reading Unit 5. Digestive System and Metabolic Physiology. Digestive system part 1 VHP Chapter 15 L20 Digestive system part 2 TE8 Digestive system L21 Metabolic Physiology VHP Chapter 16 P5 Mouse dissection Practicals Manual, Dissection guide Learning Objectives Calendar week 51. To understand the structure and function of the digestive tract and accessory digestive organs To understand the digestion of the major food groups, protein, carbohydrate and fat To understand the absorption of the major food groups To understand the regulation of the digestive tract and digestive processes by endocrine and neural factors To understand how the body uses the products of digestion and absorption To understand how the body stores, utilizes and generates “energy” and “building blocks” To understand the absorptive, post-absorptive and fasting metabolic states To recognize basic mammalian anatomy, including: digestive organs, reproductive organs, liver, kidneys, bladder, spleen, heart, lungs, brain. Key Terms VHP pages 550-551 VHP pages 568, 584 Teaching Reading Learning Objectives Unit 6. Metabolism, Growth and Ageing L22 L23 TE9 Calcium balance Growth and development Growth and Ageing VHP Chapter 11 sections F Growth and ageing manual, NOT pensum Why do women live longer than men? Opportunity for group presentation in week 3 (optional). Key Terms Calendar week 1. To understand the regulation of the uptake, storage VHP page and mobilization of calcium 351 To understand the basic cellular processes involved in growth: proliferation, differentiation, apoptosis To understand at a basic level how the process of morphogenesis is able to create complex tissues, organs and body systems To understand growth of different organs at different VHP page 344 stages of the life cycle and under different physiological circumstances To understand how growth is integrated at the tissue and whole animal level To explore the pattern of ageing in different human and animal populations To explore the cellular processes that characterize ageing To understand at a basic level the various theories that explain the ageing process Teaching L24 Reproductive physiology part 1 L25 Reproductive physiology part 2 TE10 Reading Unit 7. Reproductive Physiology VHP Chapter 17 Reproduction L26 Lactation physiology VHP Chapter 17 TE11 Parental investment and intergenerational effects Opportunity for group presentation in week 3 (optional). Learning Objectives Calendar week 2. To understand the anatomy and functioning of the male and female reproductive systems To understand the different stages of the menstrualcycle To understand the role of the hypothalamus and anterior pituitary in regulating reproductive function To understand the endocrine functions of the male and female gonads To understand the process of fertilization To understand at a basic level the processes of embryogenesis, placentation and fetal development and function To understand the processes of: Mammogenesis (mammary gland development) Lactogenesis (initiation of lactation) Milk ejection reflex (removal of milk) Galactopoiesis (maintenance of milk secretion) Mammary involution (cessation of lactation) To explore the maternal and paternal relationships with offspring To explore the maternal adaptations necessary for successful pregnancy and lactation To explore the neonatal adaptations to very early extrauterine life To explore how early life influences can have long term effects on growth, development and metabolism Key Terms VHP page 629