Download Case Analysis Worksheet

Donor’s Dilemma: CASE ANALYSIS SHEET
1.
Recognize potential issues and major topics in the case What is this case about?
Underline and list terms or phrases that seem to be important.
Then, list 3-4 biology-related topics or issues in the case.
Blood donation, viruses,
2. What specific questions do you have about these topics? By yourself, or better yet in a group, list what
you already know about this case in the ”What Do I Know?” column. List questions you would like to learn
more about in the “What Do I Need to Know?” column.
What Do I Know?
What Do I Need to Know?
There’s a virus spreading
It’s an RNA virus
Mosquitoes are vectors
Can be transmitted via blood transmission
Symptoms may or may not be observed
Current viral strain shows mutation
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How is it that WNV can establish itself
and spread east to west
How transfer? Arbovirus
What kind of virus? == mRNA virus
What are the consequences of being
infected
Other possible modes of transmission?
What is the blood bank doing? How?
What else are they checking?
What is the gene sequence?
How do they actually test for genetic
material in blood?
If genetic material, how differentiate
from human DNA/RNA?
What is the replication rate for WNV?
What conditions allow it to replicate
quickly?
Why do some show symptoms when
others don’t?
What cells does WNV target?
What is prevalence of WNV in California
at time of this case?
How many die? (mortality)
What is the incubation period of WNV?
What is the target host? Animals?
Humans?
3. Put a check mark by 1-3 questions or issues in the “What do I need to know?” list that you think are
most important to explore.
Resources from the Biological Inquiry.
2012
Waterman, M. A. and Stanley, E. D. 2004. ICBL Case Analysis Worksheet. NIE Workshops
JC-15
4. What kinds of references or resources will help you answer or explore these questions? Identify two
different resources and explain what information each resource is likely to give that will help you answer the
question(s). Choose specific resources or types of resources.
2012
Waterman, M. A. and Stanley, E. D. 2004. ICBL Case Analysis Worksheet. NIE Workshops
JC-15