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Mr. Drake Membrane is “_____________________”: only allows certain things to enter the cell The lipids prevent too much water from entering or exiting the cell Small, uncharged, molecules pass through easily (O2, CO2). Concentration of molecules is equal inside the cell and outside of the cell This is how we achieve homeostasis The cell is always moving towards equilibrium Concentration – amount of molecules in a given space Example: 5 grams/liter Transport • 1) • 2) • 3) that does NOT require energy Simplest type of transport Movement of molecules from an area of _______________________(MORE)to an area of ______________________(LESS) ______________________: difference in concentration of molecules across a space Molecules move down their concentration gradient Molecules will do this without energy Cell membranes are selectively permeable Go from high concentration to low concentration Depends on the size of the molecule, smaller is better Calcium, sodium and water pass easily Movement of _________ across the cell membrane Again, it goes from high to low concentration Does not require energy it is passive _____________: having a lower solute concentration, and therefore a higher water concentration, relative to another solution. Example: If the cell is sitting in a hypotonic solution, then water will flow into the cell. _____________: Having a greater solute concentration, and therefore a lower water concentration, relative to another solution. •_____________-having an equal solute concentration and water concentration relative to another solution. •If a cell is sitting in an isotonic solution, water will flow into and out of the cell at equal rates. Direction of osmosis Solution outside of cell Direction of Osmosis Hypotonic Water into the cell Hypertonic Water out of the cell Isotonic Into and out of the cell at equal rates = Most get to equilibrium easily as water passes across membranes Cells live in a ______________ environment, water all around them If too much water enters the cell it will burst Cells must manage water and solute levels to prevent dehydration For molecules that can’t pass through the membrane Either too large or not lipid-soluble Proteins in the membrane help push them through From high to low concentration The proteins will change their shape and this pushes the molecules through Ion channels in the cell membrane act like gates in a fence Allow sodium, calcium, potassium, and chloride to flow into cell (Ca+, K+, Cl-) Useful in nerve and muscle cells 1) Sodium-Potassium Pump 2) Endocytosis 3) Exocytosis From _________________concentration— AGAINST concentration gradient Uses energy-Active 1) ______________________: in muscle cells uses energy Creates electrical impulses like in nerve cells Push proteins and hormones “up” the concentration gradient Key to survival of animal cells Sodium potassium pump: Animals must have more sodium outside and potassium inside to allow for energy production in cells Can move small and large molecules using this method 2) ________________: large molecules like food into the cell 3)________________: Large molecules out of the cell Opposite of endocytosis, cell releases large amounts of material through the membrane Removes waste from the cell Important to maintaining homeostasis in cells Cells of animals live in a salty or “saline” solution This allows them to survive in a variety of different environments Cells must maintain fluid levels or they die Most animals will have a kidney type organism to manage these levels in the body Filter the blood of animals through osmosis and diffusion Prevent dehydration and maintain fluid levels Prevent toxins from building up in the blood Eliminate swelling in the body When Kidneys fail harmful toxins build up in the blood CKD (chronic kidney disease), cancer, aging and drug/alcohol abuse lead to kidney failure Tubing that removes toxins, Takes 3-4 hours 3 times a week