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Muscular System Muscles in Humans There are approximately 650 muscles in the human body, each performing a unique role. Muscles are the driving force behind the musculoskeletal systems, enabling us to sit, stand, walk, talk and do anything else that requires movement. They also keep our heart beating and help us breathe. In order to function, they must be able to react to stimuli, contract, extend and return to their normal shape. Muscular System Muscles are responsible for all types of body movement 3 basic muscle types are found in the body Skeletal muscle Cardiac muscle Smooth muscle Characteristics of Muscles Muscle cells are elongated (muscle cell = muscle fiber) Contraction of muscles is due to the movement of microfilaments All muscles share some terminology Prefix myo refers to muscle Prefix mys refers to muscle Prefix sarco refers to flesh Nervous system to muscles Within the nervous system, nerve impulses travel from neuron to neuron along complex nerve pathways. The junction between the parts of two such neurons is called a "synapse.“ If a sufficient amount of the substance (called "neurotransmitter") is released, the membrane is stimulated, and a nerve impulse is triggered Neuromuscular junction occurs when a nerve cell contacts a muscle Comparison of Types of Muscle Types of Muscle, cont. Myofilaments Muscle cells are unique because of the contractible protein fibers, called myofilaments, within them. the filaments of myofibrils constructed from proteins are of two types, thick and thin. Thin filaments consist primarily of the protein actin. Thick filaments consist primarily of the protein myosin. Muscle contraction occurs because of the myosin filaments pull on actin filaments Skeletal Muscle Characteristics Most attach to bones by tendon Cells are multinucleate Striated—have visible binding Voluntary Cells surrounded & bundled by connective tissue Smooth Muscle Characteristics Has no striations Spindle-shaped cells Single Nucleus Involuntary—no conscious control Found mainly in the walls of hollow organs Characteristics of Cardiac Muscle Has striations Usually has a single nucleus Joined to another cardiac muscle cell Involuntary Found only in the heart Connects cytoplasm between 2 cells (Gap junction) Gap junctions are responsible for electrochemical and metabolic coupling. They allow Each heart muscle cell is coupled to its neighbors electrically by tiny holes, producing depolarization of the heart muscle Skeletal Muscle Functions of Skeletal Muscle Produce Movement Maintain posture Stabilize joints Generate Heat Sites of Muscle Attachment Bones Cartilage Connective tissue coverings Muscle Fibers blend into a connective tissue attachment Tendon—cordlike structure Aponeurosis—sheet-like structure Properties of Muscle Irritability – ability to receive and respond to a stimulus Contractibility – ability to shorten when an adequate stimulus is received Extensibility – ability to lengthen when an adequate stimulus is received Elasticity – ability to return to normal shape Anatomy of a Muscle Cell Each fiber is built up from smaller strands called myofibrils, and each myofibril contains interlaced filaments of muscle proteins. Naming Skeletal Muscles Direction of Muscle Fibers Location Action Skeletal Muscle Origin & Insertion Size Shape Number Of Origins Direction of Muscle Fibers Relative to the Midline RECTUS = parallel to the midline TRANSVERSE = perpendicular to midline Rectus Abdominus Transverse Abdominus OBLIQUE = diagonal to midline External Oblique Location Structure near which muscle is found FRONTALIS = near FRONTAL bone OCCIPITALIS = near OCCIPITAL bone Size Relative Size of Muscle MAXIMUS = largest MEDIUS = middle Fibularis Longus BREVIS = short Gluteus Minimus LONGUS = longest Gluteus Medius MINIMUS = smallest Gluteus Maximus Fibularis Brevis TERTIUS = shortest Fibularis Tertius Number of Origins Number of tendons of origin BICEPS = Two TRICEPS = Three Biceps Brachii Biceps Femoris Triceps Brachii QUADRICEPS = Four Quadriceps Femoris Shape Relative Shape of the Muscle DELTOID = triangular shape Δ TRAPEZIUS = trapezoid shape SERRATUS = sawtoothed ♒ RHOMBOIDEUS = rhomboid shape TERES = round ○ Origin & Insertion Origin – attachment to an immoveable bone Insertion – attachment to a movable bone ILIO COSTALIS= attaches to the ilium & ribs (costal = ribs) Action NAME FLEXOR EXTENSOR ACTION EXAMPLE Decrease angle at a joint Flexor Carpi Radialis Increase angle at a joint Extensor Carpi Ulnaris ABDUCTOR Move bone away from midline Abductor Pollicis Longus ADDUCTOR LEVATOR Move bone toward midline Adductor Longus Produce upward movement Levator Scapulae DEPRESSOR Produce downward movement Depressor Labii Inferioris SUPINATOR Turn palm upward/anterior Supinator PRONATOR Turn palm downward/posterior Pronator Teres Types of Muscle--Actions Prime mover (Agonist) – muscle with the major responsibility for a certain movement Antagonist – muscle that opposes or reverses a prime mover Synergist – muscle that aids a prime mover in a movement and helps prevent rotation Fixator – stabilizes the origin of a prime mover Head & Neck Muscles Head & Neck Muscles Frontalis: elevate eyebrows Orbicularis Oculi: close eyelid Zygomaticus: draw angle of lip upward Buccinator: draws cheeks against teeth Orbicularis Oris: closes mouth Platysma: draws lower lip down & back Cranial Aponeurosis: connects frontalis to occipitalis Temporalis: elevates mandible Occipitalis: draws scalp back Masseter: elevates mandible Sternocleidomastoid: Flexes head Draws head toward shoulder Muscles of Mastication Masseter: elevates mandible Temporalis: elevates mandible Medial pterygoid: elevates mandible Lateral pterygoid: depresses mandible Key Muscles of Facial Expression Smiling Muscles Orbicularis Oculi Nasalis Levator Labii Superioris Levator Anguli Superioris Zygomaticus Risorius Frowning Muscles Frontalis Orbicularis Oris Depressor Anguli Oris Depressor Labii Inferioris Mentalis Platysma Muscles of the Axial Skeleton Muscles of the Axial Skeleton Intrinsic Muscles Erector Spinae: maintain posture of back/extension • Spinalis • Longissimus • Iliocostalis Oblique Muscles: rotation of the vertebrae Muscles of Quiet Respiration Abdominal Muscles • Semispinalis • Multifidus • Rotatores Diaphragm External Intercostals Internal Intercostals— deep breaths External Obliques Internal Obliques Transverse Abdominus Rectus Abdominus Quadratus Lumborum Muscles of Scapular Stabilization Trapezius: Retraction (M) Elevation (S) Depression (I) Upward Rotation (S, M) Rhomboid—retraction Levator Scapular—Elevation Pectoralis Major—Protraction Serratus Anterior—Protraction Anterior Muscles of Shoulder Deltoid Pectoralis Major Flexion (A, M)/Extension (P, M) Abduction (M)/Adduction (A) Internal (A) /External Rotation (P) Adduction Flexion Extension Internal Rotation Biceps Brachii—Flexion Posterior Muscles of Shoulder Teres Major Latissimus Dorsi Adduction Extension Internal Rotation Adduction Extension Internal Rotation Triceps Brachii Adduction Extension Rotator Cuff Muscles (SITS) Supraspinatus Abduction Infraspinatus External Rotation Teres Minor External Rotation Subscapularis Internal Rotation Muscles of the Elbow/Forearm Triceps Brachii— Extension Bicep Brachii— Brachialis—Flexion Brachioradialis— Flexion Supination Flexion Pronation Pronator Teres Pronator Quadratus Supinator Longus Muscles of the Wrist & Hand Flexor Carpi Ulnaris Flexor Carpi Radialis Flexor Digitorum Extensor Carpi Ulnaris Extensor Carpi Radialis Extensor Digitorum Anterior (Palmar) View Posterior (Dorsal) View Muscles Of Hip: Anterior Muscles Muscles of Hip: Anterior Muscles Medial/Adductor Muscles: Adductor Magnus Adductor Longus Adductor Brevis Gracilis Anterior Muscles Iliopsoas—Flexion Pectineus— • Flexion • Adduction Sartorius— • Flexion • Lateral Rotation Muscles of Hip: Gluteal Muscles ** Gluteus Minimus is under the Gluteus Medius Gluteus Maximus— Extension Gluteus Medius— Abduction Gluteus Minimus— Abduction Tensor Fasciae Latae— Flexion Abduction Muscles of Anterior Thigh “Quadriceps” Rectus Femoris— • Hip flexion • Knee extension Vastus Lateralis— knee extension Vastus Medialis— knee extension Vastus Intermedius— knee extension Sartorius— • Hip & Knee Flexion • Lateral Hip Rotation **Vastus Intermedius is beneath Rectus Femoris Muscles of Posterior Thigh “Hamstrings” Responsible for Knee Flexion & Hip Extension Semimembranosus Semitendinosus Biceps Femoris Gastrocnemius Knee Flexion Muscles of the Lower Leg Anterior Compartment Posterior Compartment Tibialis Anterior—Dorsiflexion & inversion Extensor Digitorum Longus Fibularis Tertius—dorsiflexion & eversion Gastrocnemius—plantarflexion, knee flexion Soleus—plantarflexion Lateral Compartment Fibularis Longus—plantarflexion & eversion Fibularis Brevis—plantarflexion & eversion Throwing Movement Running & Kicking Tendinitis Inflammation of tendons and of tendon-muscle attachments Many patients report stressful situations in their life in correlation with the beginnings of pain which may contribute to the symptoms. If the symptoms of tendinitis last for several months or longer it is probably tendinitis. Muscular Diseases Muscular Dystrophy Muscular Dystrophy (MD) is a group of genetic diseases that cause the muscle fibers to become easily damaged. There are over one dozen different types, but the most common general symptoms are muscle weakness, lack of coordination and loss of mobility. The most severe type, Duchenne's muscular dystrophy, can cause mental retardation and primarily affects young boys. MD is diagnosed through genetic tests, muscle biopsies, blood tests that measure for high levels of creatine kinase and ultrasounds. There is no cure for MD but it can be treated to reduce the severity with physical therapy, medication, surgery and special braces. Muscular Diseases Compartment Syndrome Compartment syndrome occurs when too much pressure builds up in and around the muscles. It can result from crushing injuries, extended pressure on a blood vessel, swelling inside a cast or complications from surgery. Symptoms include severe pain, a feeling of fullness or tightness in the muscle and a tingling sensation. Numbness indicates cellular death and it may be difficult to restore full function once it reaches that point. Surgery to relieve the pressure is usually required. Fibromyalgia is a medical disorder characterized by chronic widespread pain and allodynia, a heightened and painful response to pressure Fibromyalgia is estimated to affect 2–4% of the population, with a female to male incidence ratio of approximately 9:1 Fibromyalgia is considered a controversial diagnosis, due to lacking scientific consensus to its cause Signs and symptoms: Muscle spanms, weakness, nerve pain, muscles twitching, palpitations, bowel disturbances, sleep disturbances, short/long term memory, impaired speed performace, inability to multitask, anxiety, depression, RA, headaches, etc… Mitochondrial Myopathies On biopsy, the muscle tissue of patients with this disease category usually demonstrate 'ragged red' muscle fibers. These 'ragged red' fibers contain mild accumulations of glycogen and neutral lipids, and may show an increased reactivity for succinate dehydrogenase and a decreased activity for cytochrome c oxidase. Examples of Mitochondrial myopathy include: varying degrees of cognitive impairment and dementia lactic acidosis (breakdown food) strokes transient ischemic attacks hearing loss Dysmotility (digestive muscles don’t work) weight loss cardiac conduction defects