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Other arrhythmias Sinus Bradycardia Extrinsic causes o Hypothermia, hypothyroidism, cholestatic jaundice and raised ICP o Drug therapy with beta blockers, anti-arrhythmic drugs o Neurally mediated syndromes – e.g. carotid sinus syndrome, neurocardiogenic (vasovagal) syndrome, etc Intrinsic causes o Acute ischaemia and infarction of the sinus node o Chronic degenerative changes such as fibrosis of the atrium and sinus node (sick sinus syndrome) Heart Block AV Block First degree AV block o Prolongation of the PR interval Second degree AV block o Occurs when some P waves conduct and others do not o Can be caused by AMI o Type 1 (aka Mobitz 1, Wenkebach): Progressive prolongation of PR interval with o o dropped beats Type 2: a dropped QRS complex is not preceded by progressive PR elongation 2:1 or 3:1 block occurs when every second or third P wave conducts to the ventricles. This is neither Type 1 or 2 but is still a second degree block. Third degree AV block o o o o Complete heart block occurs when all atrial activity fails to conduct to the ventricles No association between P waves and QRS complexes Can be caused by congenital problems, idiopathic fibrosis, ischaemic heart disease, non-ischaemic heart disease, cardiac surgery, iatrogenic, drug-induced, infections, connective tissue diseases, neuromuscular diseases Life is maintained by a spontaneous escape rhythm Bundle Branch Block Generally shown by a widening of the QRS complex Right bundle branch block o Can occur due to an isolated congenital heart disese, myocardial disease (e.g. AMI), pulmonary disease causing cor pulmonale o Produces deep S waves in leads 1 and V6 and as tall late R wave in lead V1 Left bundle branch block o Can occur due to left ventricular outflow obstruction, coronary artery disease o Produces deep S wave in lead 1 and tall late R wave in leads 1 and V6 o Also produces abnormal Q waves ECGs