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Cellular Respiration A quick review… When we eat, we get energy (glucose and other sugars) Food energy is broken down into usable energy Energy used to bond phosphate groups to ADP to make ATP ADP – P ATP Cellular Respiration What is cell respiration??? Respiration: the process of breaking down food molecules and changing these into usable energy - ATP THE GOAL: Create ATP for cells to use Free up electrons—have high energy Cellular Respiration 2 2 34 Cellular Respiration Cellular Respiration Types of cell respiration Aerobic Processes: REQUIRE oxygen to take place A lot of energy available (efficient) Anaerobic Processes: DO NOT require oxygen to take place Get energy quickly (inefficient) Cellular Respiration 2 2 34 Glycolysis Involves Break breaking down 6-carbon sugars sugars into pyruvic acid molecules 3-Carbon molecules This No process is ANAEROBIC oxygen necessary Occurs in the cytoplasm of cells Glycolysis Glycolysis Glycolysis also creates hydrogen ions and free electrons H + The whole point of respiration = high energy ions bond with NAD+ to form NADH + H + NADH carries electrons and H + ions This process uses 4 ADP molecule and creates 4 ATP molecules Glycolysis Glycolysis TOTAL ATP PRODUCTION: Glycolysis Step 1 uses 2 ATP molecules Glycolysis Step 2 converts 4 ADP molecules into 4 ATP molecules Net ATP production = 2 ATP for every glucose molecule Glycolysis When oxygen is present, aerobic respiration occurs Happens in the mitochondria Glycolysis Breaking down Pyruvic Acid… Occurs in the mitochondria Pyruvic Acid = 3-carbon compound Broken down into… 2-Carbon compound—acetic acid Carbon Dioxide Glycolysis Intermediate 2-Carbon Step in Glycolysis Compound—Acetic Acid Combined with coenzyme A (CoA) Forms compound called acetyl-CoA This is only an intermediate step—have to move pyruvic acid into Krebs Cycle Glycolysis Glycolysis = 2 ATP Cellular Respiration 2 2 34 Citric Acid (Krebs) Cycle Produces electrons more ATP and releases more Electrons picked up by NAD + and FAD Organic carrier molecules Occurs inside mitochondria Mitochondrial Matrix Citric Acid (Krebs) Cycle Acetyl CoA combines with a 4-carbon molecule to form a 6-carbon molecule Citric Acid Citric Acid broken down into a 5-carbon compound NAD + removes electrons (NADH + H +) CO2 released Citric Acid (Krebs) Cycle 5-carbon compound broken down into a 4-carbon compound ATP created NAD + removes electrons (NADH + H +) CO2 released 4-carbon created compound (oxaloacetic acid) is Used to bond with acetyl- CoA to restart cycle Citric Acid (Krebs) Cycle Citric Acid (Krebs) Cycle Citric Acid Cycle = 2 ATP Cellular Respiration 2 2 34 Electron Transport Chain What is the ETC ? A series of molecules along which electrons are transferred, releasing energy Occurs in the mitochondria— wall of mitochondria Aerobic process Oxygen is involved Acts as the electron acceptor Electron Transport Chain As the electrons are passed between carrier proteins, energy is released ATP is created Electrons molecules NADH are given up by the carrier and FADH2 ------- NAD + and FAD Electron Transport Chain Electron Transport Chain As the electrons (H + ions) travel down the chain, they bond with oxygen 2 H + + 1 O = water (H2O) Electron acceptor Carbon is given off as carbon dioxide Electron Transport Chain Glycolysis ETC = 34 ATP Electron Transport Chain A problem exists if there is no oxygen Anaerobic process When oxygen is used up, electrons cannot be removed KEY Traffic jam in the mitochondria POINT —Electron Transport Chain cannot run without oxygen Anaerobic Respiration If no oxygen present after glycolysis, pyruvic acid can still be broken down Fermentation No ATP made during fermentation Uses electrons carried by NADH + H + so that NAD+ can regenerate for glycolysis Anaerobic Respiration Anaerobic Respiration Two types of fermentation Lactic Acid Fermentation Glucose Alcoholic Glucose 2 Pyruvic Acid 2 Lactic Acid Fermentation 2 Pyruvic Acid 2 Ethanol + 2 CO2 Anaerobic Respiration Lactic Acid Fermentation Muscle fatigue When your muscle cells require more energy than can be produced Lack of oxygen Lactic acid build up = muscle fatigue When oxygen is present, lactic acid breaks down Anaerobic Respiration Anaerobic Respiration Alcohol Fermentation Occurs in bacteria, plants and most animals Can you think of a bacteria that is used for fermentation??? Pyruvic Acid is converted into ethanol and carbon dioxide Anaerobic Respiration Cellular Respiration 2 2 34 Cellular Respiration General Formula C6H12O6 + 6 O2 6 CO2 + 6 H2O