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Breast Clinic Breast cancer is the second most common cancer in Indian women. The incidence is more in urban than rural women. It is more prevalent in the higher socio-economic groups. The average incidence rate varies from 2228 per 100,000 women per year in urban settings to 6 per 100,000 women per year in rural areas. Typically, breast cancer arises from cells lining the milk ducts and slowly grows into a lump. A malignant tumour has the ability to spread beyond the breast to other parts of the body via the lymphatics or the blood stream. Breast cancer is also one of the curable cancers if detected early. Women with a higher than average risk of developing breast cancer may be offered screening and genetic testing for the condition. Increased awareness of breast cancer risk in the past decades has led to an increase in the number of women undergoing mammography for screening, leading to detection of cancers in earlier stages and an improvement in survival rates. The various abnormalities of the breast include nipple discharge, inflammations, ANDI, benign disorders, phyllodes / sarcomas and carcinoma. Most breast cancers are epithelial tumors that develop from cells lining ducts or lobules. Cancers are divided into carcinoma in situ and invasive cancer. Breast cancer invades locally and spreads initially through the regional lymph nodes, bloodstream, or both. Advanced breast cancer may affect almost any organ in the body—most commonly, lungs, liver, bone, brain, and skin. Most breast cancers may present as Painless lump in the breast Dimpling of skin over breast Change in contour over the breast Rash or ulcer over the nipple Indrawing/retraction of the nipple Blood stained discharge through the nipple Ulceration of the nipple Lump or fullness in the armpit Arm swelling During a physical examination a lump is felt distinctly different from the surrounding breast tissue. More advanced breast cancers are characterized by fixation of the lump to the chest wall or to overlying skin, by satellite nodules or ulcers in the skin. Matted or fixed axillary lymph nodes suggest tumor spread. The triple assessment of breast lump is helpful in the diagnosis of breast carcinoma and includes: clinical examination, radiological investigation (Mammography, Ultrasound of breast and or MRI of breast) and pathological correlation. Confirmation of malignancy with cytology or histology is the minimum requirement for “indeterminate” or “high-risk” solid lesions. Fine-needle aspiration / Tru cut / core biopsy / surgical excision/ Incision biopsy / percutaneous breast biopsy for non-palpable disease are the various methods used to obtain tissue for pathological confirmation. The TNM staging is traditionally used to stage breast cancer. Patients are clinically grouped into one of the following categories Operable Breast Cancer Large Operable Breast Cancer Locally Advanced Breast Cancer Metastatic Breast Cancer Breast cancer can be treated using a multimodality approach of surgery, chemotherapy, radiotherapy and targeted therapy. The treatment options vary as per the stage of the tumor. The doctor chooses the treatment modality after many considerations like stage of disease, logistics of treatment implementation and your choices. Hence two patients in the same stage may receive different treatments. At present, we have four established modes of treatment, aiming firstly to cure and secondly to improve quality of life – Surgery Chemotherapy Radiotherapy Hormonal therapy Breast Clinic at Fortis Hospital Jaipur provides comprehensive breast cancer management using evidence-based protocols, with emphasis on early detection, breast conservation, sentinel lymph node biopsy, oncoplastic procedures to reduce surgical morbidity; and high quality adjuvant treatment. I- The following services relating breast cancer management are offered: Screening: opportunistic screening with clinical breast examination, mammography, breast ultrasonography. Diagnosis: including fine needle aspiration cytology, core biopsy, etc. Surgical Management: Includes a whole range of breast surgical procedures with emphasis on breast conservation, sentinel lymph nodes biopsy, onco-plastic and breast reconstructive procedures, and on quality of breast and axillary surgery. Commonly performed procedures include: Modified radical mastectomy Simple mastectomy with sentinel lymph node biopsy Wide local excision with sentinel lymph node biopsy with/ without axillary clearance Oncoplastic procedures Breast reconstructive procedures using pedicle flaps/ prosthesis (Implant) Chemotherapy ports implantation and removal Neo-adjuvant chemotherapy/ other neo-adjuvant treatment for large/ locally operable breast cancers for facilitate safe and effective surgical treatment, and to offer breast conservation to selected patients of this group Adjuvant treatment Adjuvant chemotherapy Adjuvant Hormone treatment Adjuvant biological therapy: Trastazumab for HER 2 neu positive cases and other targeted therapy Specialized Supportive Care: Pain management, management of post-mastectomy arm lymphedema, bone health management, well trained nursing care etc. Follow-up including tele-follow up II- Benign Breast Disease (Nipple Discharge, Breast Lump like Fibroadenoma, Fibrocystic Disease i.e. ANDI) III- Aesthetic breast surgery IV- Surgery for carcinoma in male breast and for gynecomastia