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Name: AP Statistics C.5 Producing Data 5.1 Designing Samples – Notetaking Guide Observational Study: Experiment: Population: Sample: Census: Sample Design - Random Simple Random Sample: Ways to get a SRS. Systematic Sample: Stratified Random Sample: Multistage Sampling: Cluster Sample: Sources of Bias Bias: Sample Design – Not Random Voluntary Response Sample: Convenience Sample: Nonresponse: Wording Effect: Other Types of Bias. Undercoverage: Response Bias: Using the Random Digits Table A corporation employs 2000 male and 500 female engineers. A stratified random sample of 200 male and 50 female engineers gives each engineer 1 chance in 10 to be chosen. This sample design gives every individual in the population the same chance to be chosen for the sample. Is it a SRS? Explain your answer. Beginning with line 108 on the Random Number Table, reproduced below, select the first 5 female engineers to be in the sample. 5.2 Designing Experiments – Notetaking Guide Terms and Concepts: Explanatory Variables Response Variables Experimental Units Treatments Subjects Factors Levels Example: Over a 4-month period, among 30 people with bipolar disorder, patients who were given a high dose of omega-3 fatty acids from fish oil improved more than those given a placebo. Experimental Units Treatments Factors Levels Response Variable Example: Scientists examined the glycogen content of rats’ brains at the rats’ normal bedtimes and after they had been kept awake for an extra 6, 12, or 24 hours. The scientists found that glycogen was 38% lower among rats that had been sleep-deprived for 12 hours or more, and that the levels recovered during subsequent sleep. These researchers speculate that we may need to sleep in order to restore the brain's energy fuel Experimental Units Treatments Factors Levels Response Variable Example: In this hypothetical experiment, the researcher is studying the possible effects of Vitamin C and Vitamin E on health. The Vitamin C has three doses - 0 mg per day, 250 mg per day, and 500 mg per day. The Vitamin E has 2 doses - 0 mg per day and 400 mg per day. Experimental Units Treatments Factors Levels Response Variable Experimental Design Three Important Characteristics of an Experiment: Control: Randomization: Replication: How to Control: Control group: Blinding: Placebo: Double Blind: Placebo Effect: Completely Randomized Design: Example: Design a randomized experiment for this situation. Acme Medicine is conducting an experiment to test a new vaccine, developed to immunize people against the common cold. To test the vaccine, Acme has 1000 volunteers - 500 men and 500 women. The participants range in age from 21 to 70. When are things said to be statistically significant? Block Design vs. Matched-Pairs Design Block Design: Matched-Pairs Design: Examples We know that a medication has a greater effect A study is conducted to see how effective aspirin on men than on women…this would be a is in reducing temperature in children. A sample confounding variable. Control for that by of 7 children suffering from influenza had their grouping men together and women together and temperatures taken immediately before and 1 then comparing the results of a drug treatment. hour after administration of aspirin. The results are given below. We would like to conduct a paired differences t-test for this situation. The data follow. Examples. Decide what type of design is needed. Suppose a doctor wants to compare the anxiety-controlling drug currently on the market with two new drugs. A group of patients from a local clinic is available for the experiment. All three drugs are known to have different effects on men and women. Design an experiment to compare the effects of the three drugs. A local sickle-cell association offers programs to educate people about sickle-cell anemia. The director of the association is interested in assessing the program’s effect on the participants’ knowledge about the disease. Design an experiment to assess the effectiveness of this educational progress. A pharmaceutical company wishes to test a new medication it thinks will reduce cholesterol. A group of 20 volunteers is formed and each has his or her cholesterol measured. After 6 months the volunteers’ cholesterol is measured again and any change from the beginning of the experiment is noted. The researcher believes the initial cholesterol level may influence the change in cholesterol level. Create a design that takes account of subjects’ initial cholesterol level. 5.3 Simulations – Notetaking Guide Three ways to answer questions involving chance: How to Perform a Simulation: 1. 2. 3. 4. 5. Example of digit assigning: 70% of people are employed. You are going to SIMULATE a sample of size 18 to look at unemployment rates. How could you assign the digits? Example 1: Orders of frozen yogurt flavors have the following relative frequencies: 38% chocolate, 42% vanilla, and 20% strawberry. We wish to simulate 10 frozen yogurt sales based on recent history. What are we going to do? What can we assume? Assign digits: Complete 10 TRIALS of 10 sales? Analysis: 67642 05204 30697 44806 96989 68403 85621 45556 35434 09532 64041 99011 14610 40273 09482 62864 01573 82274 81446 32477 17048 94523 97444 59904 16936 39384 97551 09620 63932 03091 93039 89416 52795 10631 09728 68202 20963 02477 55494 39563 Example 2: Suppose you take a true-false quiz and guess four answers at random. What is an experimental probability that you will get at least three correct answers? What are we going to do? What can we assume? Assign digits: Perform the simulation - 10 TRIALS 40779 86382 48454 65269 91239 45989 45389 54847 77919 41105 43216 12608 18167 84631 94058 82458 15139 76856 86019 47928 96167 64375 74108 93643 09204 98855 59051 56492 11933 64958 Analysis: Calculator procedure for the same problem. Example 3: A couple plans to have children until they have a girl or until they have four children, whichever comes first. Perform a simulation to estimate the likelihood they will have a girl. What are we going to do? What can we assume? Assign digits: Perform the simulation - 20 TRIALS 65285 97198 12138 53010 94601 15838 16805 61004 43516 17020 17264 57327 38224 29301 31381 38109 34976 65692 98566 29550 95639 99754 31199 92558 68368 04985 51092 37780 40261 14479 Analysis: Calculator procedure for the same problem. Just for grins and giggles: What is the average number of boys that the couple might have?