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Chapter 5: Producing Data 5.1 Designing Samples (pp. 269-285) 1. What is an observational study? An observational study observes individuals and measures variables of interest but does not attempt to influence the responses. 2. What is an experiment? An experiment deliberately imposes some treatment on individuals in order to observe their responses. 3. Which of these can show a causal relationship? An experiment can show a causal relationship. 4. Explain the difference between a population and a sample. The population is the entire group of individuals that we want information about. A sample is a part of the population that we actually examine in order to gather information. 5. Explain the difference between sampling and a census. Sampling involves studying a part in order to gain information about the whole. A census attempts to contact every individual in the entire population. 6. Why are voluntary response samples unreliable? A voluntary responses sample consists of people who choose themselves by responding to a general appeal. Voluntary response samples are biased because people with strong opinions, especially negative opinions, are most likely to respond. 7. Why might convenience sampling be unreliable? A convenience sample is chosen for convenience. Convenience sampling chooses the individuals who are easiest to reach. This sample may be unreliable because the collection of individuals may not be representative of the entire population 8. What is a biased study? The design of a study is biased if it systematically favors certain outcomes. 9. What is meant by the design of a sample? The design of a sample refers to the method used to choose the sample from the population. 10. Define simple random sample. A simple random sample (SRS) of size n consists of n individuals from the population chosen in such a way that every set of n individuals has an equal chance to be the sample actually selected. 11. What two properties of a table of random digits make it a good choice for creating a simple random sample? A table of random digits is a long string of the digits 0, 1, 2, 3, 4, 5, 6, 7, 8, 9, with these two properties: 1) Each entry in the table is equally likely to be any of the 10 digits 0 through 9. 2) The entries are independent of each other. That is, knowledge of one part of the table gives no information about any other part. 12. What are the two steps for choosing a SRS? Step 1: Label. Assign a numerical label to every individual in the population. Step 2: Table. Use Table B (or calculator) to select labels at random. 13. What is a probability sample? A probability sample is a sample chosen by chance. We must know what samples are possible and what chance, or probability, each possible sample has. 14. What is a stratified random sample? To select a stratified random sample, first divide the population into groups of similar individuals, called strata. Then choose a separate SRS in each stratum and combine these SRSs to form the full sample. 15. Give an example of undercoverage in a sample. Undercoverage occurs when some groups in the population are left out of the process of choosing the sample. 16. Give an example of nonresponse bias in a sample. Nonresponse bias occurs when an individual chosen for the sample can’t be contacted or does not cooperate. 17. How can the wording of questions cause bias in a sample? Give an example. Confusing or leading questions can introduce strong bias, and even minor changes in wording can change a survey’s outcomes. EX: “Some cell phone users have developed brain cancer. Should all cell phones come with a warning label explaining the danger of using cell phones?” 18. Which gives more accurate results, large samples or small samples? Larger random samples give moe accurate results than smaller samples. 5.2 Designing Experiments (pp. 290-306) 1. Explain the difference between experimental units and subjects. The experimental units are the individuals on which the experiment is done. When the units are human beings they are called subjects. 2. Define treatment. A treatment is the specific experimental condition applied to the units. 3. Give an example of at least two levels of a factor in an experiment. Two factors could be giving beta carotene and giving aspirin to subjects in an experiment. 4. Describe the placebo effect. A placebo is a dummy treatment. Many patients respond favorably to any treatment, even a placebo. This may be due to trust in the doctor and expectations of a cure, or simply to the fact that medical conditions often improve without treatment. Favorable response to a dummy treatment is the placebo effect. 5. What is the significance of using a control group? The group of patients who receive the dummy treatment or placebo is the control group. Use of a control group enables us to control the effects of outside variables on the outcome. Control is the first basic principle of statistical design of experiments. 6. Define randomization. Randomization is the use of chance to divide experimental units into groups. It is an essential ingredient for good experimental design. When all experimental units are allocated at random among all treatments, the experimental design is completely randomized. 7. Define statistically significant. An effect is statistically significant if an observed effect is so large that it would rarely occur by chance. 8. What are the advantages of a double-blind study? In a double-blind experiment, neither the subjects not the people who have contact with them know which treatment a subject received. 9. Describe a block design. A block is a group of experimental units or subjects that are known before the experiment to be similar in some way that is expected to affect the response to the treatments. In a block design, the random assignment of units to treatments is carried out separately within each block. 10. Describe a matched pairs design. Matched pairs are a common form of blocking for comparing just two treatments. In some matched pairs designs, each subject receives both treatments in a random order. In others, the subjects are matched as closely as possible, and one subject in each pair receives each treatment. Blocks allow us to draw separate conclusions about each block. 11. What is the most serious potential weakness of experiments? The most serious potential weakness of experiments is lack of realism. The subjects or treatments or setting of an experiment may not realistically duplicate the conditions we really want to study. 12. What are the basic principles of statistical design for experiments? The three basic principles of statistical design are: Control the effects of lurking variables on the response, most simply by comparing two or more treatments. Randomize – use impersonal chance to assign experimental units to treatments. Replicate each treatment on many units to reduce chance variation in the results. 5.3 Simulating Experiments (pp. 309-316) 1. What is simulation? Simulation is the imitation of chance behavior, based on a model that accurately reflects the experiment under consideration. 2. List the five steps for conducting a simulation: Step 1: State the problem or describe the experiment Step 2: State the assumptions. Step 3: Assign digits to represent outcomes. Step 4: Simulate many repetitions. Step 5: State your conclusions.