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Jennifer Meneghin 517 NW 25th St. Gresham, OR 97030 (503) 703-4063 [email protected] Recent Experience Reysenbach Lab, Biology Department, Portland State University, Portland, OR Bioinformatics Research Associate, 2003-2004, 2005-2007, 2008-2011, 2012-2013 Designed, developed and used a protocol for de novo assembly of genomes using Illumina reads (http://alrlab.research.pdx.edu/aquificales/genometools_content.html). Designed, developed and used a protocol for preliminary analysis of metatranscriptome (cDNA pyrosequenced) data (http://alrlab.research.pdx.edu/aquificales/genometools_content.html). Designed, developed and used a protocol for clustering data into operational taxonomic units (OTUs) using 16S rRNA pyrosequencing data (http://alrlab.research.pdx.edu/aquificales/genometools_content.html). Designed and developed a MySQL database on a Linux system to house data for all known Aquificales species. Designed and developed the Aquificales Data Warehouse website using Perl, JavaScript, SQL and HTML on a Linux system which allows users to browse and submit new data to the Aquificales database (http://alrlab.research.pdx.edu/aquificales). Designed and developed 60 Perl scripts, one Java script and two Python scripts for genomic sequence analysis that have been made publicly available on the Aquificales Data Warehouse website (http://alrlab.research.pdx.edu/aquificales/bioinformatics_scripts.html). Designed and developed a web-based data mining tool, using Java servlets and HTML on a Linux system, for analyzing the lab’s microbial diversity data that performs Kruskal-Wallis and Wilcoxon Rank Sum tests. Designed and developed a database to house all of the lab’s samples and experimental data. The system was implemented in MySQL on a Linux server. Designed and developed a web-based data entry tool for sample data collected in the field that uses a CGI script written in Perl to error check the data and import it into the MySQL database. Mitchell Lab, Computer Science Department, Portland State University, Portland, OR Research Assistant, 2006-2008 Implemented the AdaBoost algorithm, a boosting algorithm intended to work over another base algorithm, on an evolutionary learning algorithm that evolves cellular automata to perform a classification task. Performed and tracked experiments comparing the performance of the evolutionary algorithm with and without AdaBoost. The AdaBoost algorithm has been implemented in C++ on a Linux system. Designed and developed a user interface for visualizing one-dimensional cellular automata using C++ and Java. Goodman Lab, Vollum Institute, Oregon Health & Science University, Portland, OR Bioinformatics Research Associate, 2004-2005 Designed and developed an Oracle database used to compare a full spectrum of annotated genomic data to specific transcriptional regulatory regions of interest to the lab for human, mouse and rat genomes. Designed and developed a web-based tool, using Java servlets and HTML, that allows researchers to import locations of transcriptional regulatory regions of interest into the database and run any of several reports comparing these locations to previously annotated genomic regions for human, mouse and rat genomes. Gartner/Griggs-Anderson Research, Portland, OR Senior Software Engineer, 2000-2002 Designed and developed an application in Java on Linux that sends out bulk e-mails, tracks the e-mails in a Sybase database, then parses, forwards, and tracks any replies received, including extensive decision making to automatically deal with bounced e-mails. Worked on a team that designed and developed an application in Java on Linux that automatically generates trended graphical reports (bar charts, pie charts, etc.) from survey data housed in a Sybase database. It included a graphical user interface, and the ability export reports to HTML. Worked on a team that designed and developed a large-scale panel application in Java on Linux. This project included a web survey engine, bulk e-mailing, e-mail tracking, multiple graphical user interfaces and extensive reporting. Designed a “win/loss” application for the statistics department. Worked on a team that developed the back-end database and analysis side of the application in Java on Linux. Software Engineer, 1997-2000 Designed and developed an application in Java on UNIX for the statistics department that searches for latent classes by estimating maximum likelihood for various types of data distributions. Developed many web surveys using Perl, connected to a Sybase database, on a UNIX system. Unpaid Experience Department of Biology, Portland State University, Portland, OR Teaching Assistant, 2012 Taught two Python programming classes for Computing for Biologists class. Participated and answered questions weekly. Biostatistics and Bioinformatics Shared Resource, Oregon Health & Science University, Portland, OR Practicum, 2004 Used JSP and Java servlets to develop a general purpose query tool for an Oracle database that houses Affymetrix microarray data. Publications Hamamura, N., Meneghin, J. & Reysenbach, A. L. 2013. Comparative community gene expression analysis of Aquificales-dominated geothermal springs. Environmental Microbiology, 15, 4: 1226-1237 Flores, G., Shakya, M., Meneghin, J., Yang, Z. K., Seewald, J. S., Geoffwheat, C., Podar, M. & Reysenbach, A. L. 2012. Inter-field variability in the microbial communities of hydrothermal vent deposits from a back-arc basin. Geobiology, 10, 4: 333-346. Flores, G., Campbell, J. H., Kirshtein, J. D., Meneghin, J., Podar, M., Steinberg, J. I., Seewald, J. S., Tivey, M. K., Voytek, M. A., Yang, Z. K. & Reysenbach, A. L. 2011. Microbial community structure of hydrothermal deposits from geochemically different vent fields along the Mid-Atlantic Ridge. Environmental Microbiology, 13, 8: 2158-2171. Education Graduate Certificate, Biomedical Informatics (GPA 4.0) Oregon Health and Science University, Portland, OR, 2003-2004 Computer Science/Electrical Engineering Classes, 16 graduate credit hours: Computability Theory I & II, Genetic Algorithms, Programming Languages and Artificial Intelligence Portland State University, Portland, OR, 1993-1994, 2003, 2007 Computer Science Classes, 36 undergraduate credit hours Portland State University, Portland, OR, 1991-1993 Bachelor of Science, Major in Mathematics with an emphasis on Statistics, Minor in Psychology Portland State University, Portland, OR, 1987-1990, Graduated in three years Sherwood High School, Sherwood, OR 1984-1987, Graduated in three years Skills Programming Languages: Perl, Python, JavaScript, HTML, Java (RMI, JDBC, JavaMail, JSP, Servlets, JUnit), C/C++ Bioinformatics Tools: BLAST, Primer, RDP Pipeline, Mothur, ESPRIT, GenePix, Ecosim, SPSS, MS Excel, SolexaQA, Euler, Velvet, Geneious, SOAP, BioPerl Database Management Systems: SQL, Sybase, MySQL, Oracle, PostgreSQL, MS Access Operating Systems: UNIX, Linux, Windows Interests Bioinformatics, Metagenomics, Biostatistics, Data Mining, Data Modeling, Evolutionary Computation, Genetic Algorithms