Download Catalog # 10-1111 Verapamil HCl Clinically useful L

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Transcript
Catalog # 10-1111
Verapamil HCl
CAS# 152-11-4
5-[N-(3,4-Dimethoxyphenylethyl)methylamino]-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile hydrochloride
Lot # Z101503
Clinically useful L-type calcium channel blocker.1 It is also used as an inhibitor of drug efflux
pump proteins.2
1) Brgden and Benfield (1996) Verapamil: a review of its pharmacological properties and therapeutic use in
coronary artery disease Drugs 51 792
2) Safa et al. (1987) Identification of the multidrug resistance-related membrane plycoprotein as an acceptor for
calcium channel blockers J. Biol.Chem. 262 7884
PHYSICAL DATA
Molecular Weight:
Molecular Formula:
Purity:
Solubility:
Physical Description:
Storage and Stability:
491.06
C27H38N2O4·HCl
>98% by TLC
NMR: Conforms
Water (up to 50 mg/mL); DMSO (up to 20 mg/mL)
White
Store as supplied at room temperature for up to 2 years from the date of purchase. Protect from
exposure to moisture. Solutions may be stored at -20°C for up to 3 months.
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.
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