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TISSUE ORGANIZATION Histology - is the study of tissues EMBRYONIC GERM LAYERS Ectoderm - epidermis of the skin,nervous system Endoderm - functional lining of the digestive, respiratory tract; accessory organs and glands such as lungs, stomach,pancreas Mesoderm - skeletal system, muscular system, and circulatory system MAIN TISSUE TYPES Epithelial Connective Muscle Nervous EPITHELIAL TISSUE Location –sheets or layers lining body tubes, cavities, or covering body surfaces –Form many glands GENERAL CHARACTERISTICS Form sheets, layers Cells fit together tightly One edge attached to basement membrane No blood supply Regenerate quickly Many are secretory Supported by connective tissue FUNCTIONS Protection Absorption Filtration Secretion Gas exchange EPITHELIAL TISSUE TYPES Number of layers – simple epithelium – stratified epithelium – pseudostratified epithelium Shape of cells – squamous (flat) – cuboidal ( cubed) – columnar ( tall) – transitional (varies) Examples of Epithelial Tisuue Simple squamous Simple cuboidal Simple columnar Simple columnar – ciliated Pseudostratified columnar Stratified squamous – keratinized – non-keratinized Stratified cuboidal Stratified columnar Transitional Glandular Glandular Epithelial Tissue Types endocrine (ductless) - secrete hormones into blood exocrine- secrete through ducts to specific locations • unicellular - “goblet cells” • multicellular –modes of secretion »apocrine - apex pinches off »holocrine - accumulate until rupture »merocrine -most common;secrete by exocytosis CONNECTIVE TISSUE Most abundant and widespread tissue found in the body GENERAL CHARACTERISTICS Many types with great diversity Very good blood supply Cells usually spaced apart from each other Intercellular material (matrix) separating cells No free surface Derived from mesenchyme Consist of ground substance, fibers, cells Connective Tissue Functions Physical protection Support Binding Absorb shock Insulation Stores energy Blood production Immunity Types of Fibers Collagen - very tough and strong – contains collagen protein Elastic - very flexible and stretchable – contains elastin protein Reticular - forms network mesh – contains collagen & glycoprotein Types of Cells Fibroblast - “fiber- Plasma cells - forming cells” produce antibodies Macrophage - “big eaters” phagocytic white WBC - neutrophils, blood cells basophils, Mast cell - sentry cells; eosinophils, detect foreign substances; lymphocytes, produce inflammatory monocytes chemicals – heparin; histamine Adipose - store fat Connective Tissue Proper Loose Connective(Areolar) - attaches skin to underlying body parts; superficial fascia Adipose - energy storage; insulation Reticular - binds smooth muscles together Regular dense connective tissue(fibrous) – tendon; ligaments Irregular dense – fascia, periosteum Elastic connective – blood vessels, lung tissue Cartilage Hyaline cartilage (gristle) – ends of long bone, nose tip, connects ribs to sternum Elastic cartilage – external ear Fibrocartilage – between pubic symphysis – discs between vertebrae OSSEOUS TISSUE - BONE MATRIX 30% collagen fibers 70% mineral salts Osseous Tissue Types of Cells – osteocytes – osteoblasts – osteoclasts Types of Bone – Cancellous (Spongy) Bone - trabeculae – Compact Bone - Haversian Canal System Blood Tissue (Vascular) Hemopoietic Tissue (blood forming tissue) Types of Cells: – erythrocytes (RBC’s) – leukocytes (WBC’s) – platelets (thrombocytes) MUSCLE TISSUE Contractile tissue Responsible for movement Skeletal Muscle - Voluntary Long, threadlike cells with parallel fibers Cells are multinucleate with nuclei located peripherally; striated Usually attached to long bones Smooth Muscle - Involuntary Spindle shaped cells with single nucleus per cell No striations Located in blood vessels, walls of hollow organs, and the gastrointestinal tract Cardiac Muscle - Involuntary Branched cells with striated fibers Intercalated discs Only a single nucleus per cell Only found in the heart NERVE TISSUE Characterized by the ability to conduct electrical signals Nervous Tissue Located in the brain and spinal cord (CNS) and in the nerves (PNS) Sensitive to changes in the internal and external environment Conducts nerve impulses to other neurons/body parts NERVE TISSUE Functions in coordinating, regulating, and integrating body activities Types of Cells: – neuroglial cells - support cells – neuron - cell body, axon, dendrites MEMBRANES Thin sheet or layer of tissue that covers a structure or lines a cavity Epithelial Membranes Cutaneous membrane - skin Serous membrane - (serosa) – found in closed cavities • parietal membrane - lines inside of cavities • visceral membrane - covers organs Mucous membrane - mucosa – line cavities that open to the exterior Connective Tissue Membranes Synovial Membrane –line spaces between bones in joints –secrete synovial fluid