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Living with Heart Failure Ayesha Hasan MD, FACC Advanced Heart Failure and Transplantation Program Medical Director Cardiac Transplant Program Contact information: 614-293-6081 (heart failure office) What is Heart Failure? Heart failure is NOT a heart attack Heart failure means the heart is: Weakened Cannot pump enough blood to supply the body’s needs . . . It does not mean the heart has stopped working! Heart Failure is Very Common Heart failure affects nearly 5 million Americans 50% men and 50% women An estimated ½ million new cases are diagnosed each year Expected to rise to 750,000 new cases by 2040 Related to aging population, better treatment of heart disease and risk factors, awareness Over one million heart failure hospitalizations annually Rising over past few decades Accounts for over 20% admissions in people 65 and over Types of Heart Failure: Difference Between Systolic and Diastolic Heart Failure Aorta LA LV Normal Normal ejection (squeeze) =Systolic function Normal relaxation (filling) =Diastolic function Dilated Systolic Heart Failure Thickened or stiff heart walls Diastolic Heart Failure Weakened pump Normal ejection Relaxation ± abnormal Abnormal relaxation: Stiff or scarred Blood backs up and overloads the heart Won’t allow enough blood to fill the heart before it squeezes Pg 238, Lilly 3rd edition Simplified View of Heart Failure Normal Heart Development of Heart Failure What Causes Heart Failure? Heart failure results after injury to the heart High blood pressure Heart attack Damage to heart valves Diabetes High cholesterol Heart muscle disease: damage from drugs, alcohol, or infections Congenital heart disease What Are The Symptoms of Heart Failure? Think FACES... • Fatigue Constant lack of energy • Activities limited Difficulty with everyday activities • Chest congestion Dry cough or producing white or pink bloodtinged phlegm • Edema or ankle swelling Swelling of the feet, ankles, legs, abdomen, or unexplained weight gain • Shortness of breath Breathlessness during activity, at rest, or while sleeping Additional symptoms: Lack of appetite, nausea, increased heart rate, irregular heart rhythm How Severe is A Patient’s Heart Failure? We measure the “ejection fraction” by echo The fraction of blood that the heart pumps with every beat We assess the patient’s symptoms No or mild symptoms Do symptoms limit activity? If so, how much? Treatment…Begins with Prevention! Symptomatic Heart Failure Coronary Artery Disease Risk Factors Left Ventricular Hypertrophy Family History Diabetes Smoking High cholesterol Obesity High Blood Poor Diet Pressure Lack of Exercise How Do We Treat Heart Failure? Lifestyle Changes Quit smoking Monitor diet: low-fat, low sodium Exercise regularly Lose weight Avoid alcohol Limit caffeine intake Limiting Sodium or Salt Will Improve Your Heart Failure Symptoms Sodium is a component of salt Naturally occurring in many foods Sodium attracts fluid Added during processing In most foods eaten away from home Your body needs only a small amount of sodium to keep a normal fluid balance. Fluid build-up in body Extra work on heart & kidneys to get rid of fluid Higher BP often results Too much sodium causes your body to hold onto fluid and cause symptoms of weight gain, shortness of breath, Heart failure symptoms, heart attack, stroke and fatigue. The more sodium (salt) you take in, the more fluid your body holds on to Patients Should Follow a 2000 mg Sodium Diet In addition to heart failure patients, the American Heart Association recommends 1) All adults older than 51 2) All African Americans 3) Anyone with high blood pressure limit their daily intake to 1500 mg Plan your meals for 2000 mg intake MEAL Breakfast Lunch Dinner mg Sodium 600mg 600mg 600mg Snack 200mg Use alternative seasonings! Basil Chives Dill weed Garlic Tarragon Thyme Parsley Paprika Pepper Sage Mrs. Dash Lemon, lime juice How It Shakes Out ¼ tsp salt = 600 mg sodium ½ tsp salt = 1200 mg sodium 1 tsp salt = 2300 mg sodium More than daily recommendation Even a small amount of salt counts! ½ tsp salt = 1 serving pretzels = 3 slices of ham =2 packets of soy sauce = 3 pickles = 14 green olives Some common high sodium foods Frozen meals Pickles Canned foods Bacon Breads, baked goods Anchovies Lunch & smoked meats Soy sauce Cheese Seasoning mixes Condiments (salad dressing) Gravy Olives Salted crackers Pretzels FAST FOOD Rule of thumb: the more processed the food, the more sodium it contains First step: Learn how to read sodium labels on all food 1. Look for Sodium Listed as milligrams or mg 2. Next, look at serving size If you eat 2 servings of a food you need to double what you see on the label 3. Reduced-sodium products still contain sodium Always read the label Sodium Guidelines < 140 mg = low sodium 140-400 mg = medium sodium > 400 mg = high sodium Enjoy these foods! Use food in moderation Use this food sparingly Low sodium 140 mg or less sodium per serving Very low sodium 35 mg or less sodium per serving Sodium-free Less than 5 mg sodium per serving 1. Use salt substitute or other spices when cooking (watch for high potassium in some substitutes) 2. Don’t add salt at the table Fluid intake & Daily Weights Limiting fluid intake: important in managing heart failure REMEMBER: Anything liquid at room temperature is considered a fluid Daily weights: every morning at the same time using the same scale Keep track of daily weights REMEMBER: You might not see swelling until you are 8-15# up Exercise: Get Off the Couch! Exercise Will Improve Your Quality of Life Pick a simple aerobic activity that you enjoy Start slowly and increase gradually Need to move large muscle groups Walking is a great first choice Resume activities you stopped (gardening, bowling, fishing) Work your way up to 30 minutes most days Doesn’t have to be 30 minutes in a row Warm up and cool down Check with your physician first if You are really out of shape, uncertain about your abilities, or have shortness of breath with very mild activity Exercising & Precautions Find an indoor location along with a partner Build muscle (stretching, elastic bands, light weights) Overexertion Shortness of breath that prevents you from completing a sentence or doesn’t get better with rest Dizziness, chest pain, nausea, vomiting, severe sweating, unusual fatigue (extreme) What Medications Do We Use in Heart Failure and Why? Diuretics Digitalis Beta-blockers ACE inhibitors Hydralazine/nitrates Spironolactone 1. To reduce symptoms 2. To prevent disease progression 3. Keep patients out of the hospital 4. Improve survival Be careful about alternative therapy (chinese herbs, hawthorne, ginseng): No evidence they help & associated with some negative effects Why Do We Use These Treatments? Heart failure limits a patient's ability to perform the routine activities of daily living… Diuretics, ACE Inhibitors Reduce the number of sacks on the wagon (or load on the heart) ß-Blockers Limit the speed, thus saving energy Spironolactone, Cardiac Resynchronization Therapy Increase the heart’s efficiency What if the Heart is Still Weak After Medications? Risk of death from cardiac arrest Defibrillators can protect the heart from these abnormal rhythms Based on the ejection fraction History of Pacemakers & Defibrillators What if the Heart is Still Weak After Medications? The heart “pump” worsens Newer devices can be implanted to help the heart’s contraction 1. Pacemakers (resynchronization) 2. Ventricular assist devices 3. Clinical trials: investigational devices Heart transplant Pace both ventricles of the heart to make it stronger & more efficient Ventricular Assist Devices Try to be as active as possible with the following limitations: No driving No contact sports No high “bounce” activities like running, jumping, or jumping jacks No submerging in water. Stay out of bathtubs, hot-tubs, swimming pools, lakes & ponds Do not drive or operate heavy machinery Continue to follow heart failure recommendations: sodium and fluid restriction, daily weight Indications for Mechanical Circulatory Support in Advanced HF Bridge to Transplant (BTT) Non-reversible left heart failure High mortality risk Candidate for cardiac transplantation Destination Therapy (DT) Not a candidate for cardiac transplantation Bridge to Recovery Potentially reversible (post-heart attack, postpregnancy, myocarditis) ADULT HEART TRANSPLANTATION % OF PATIENTS BRIDGED WITH MECHANICAL CIRCULATORY SUPPORT* (Transplants: 1/2000 – 12/2009) 50 % of patients 40 30 20 10 0 2000 2001 2002 2003 2004 2005 Year 2006 2007 * LVAD, RVAD, TAH Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132 2008 2009 History of Heart Transplantation at Ohio State University Heart transplant program started in 1986 To date, have performed 382 transplants Includes a joint heart/kidney transplant program Average 15 transplants per year Around 2000-2500 transplants in the nation per year Approximately 3500 reported worldwide per year Cardiac Transplantation: Are There Gender Differences in Transplant Rates? Of total reported transplants, what % patients are women? a. 25-30% b. 50-60% c. 70-75% International Statistics (ISHLT registry) Of 22,387 reported heart transplants between 2002-2010, 77% were men Improved to 31% women for Jan 2011 to Dec 2011 Is the OSU transplant program similar? 11 of 37 transplants are women – 27% (Past 3 yrs - 1/2010 to present) Current waitlist – around 20% are women Taylor DO, et al. JHLT 2009;28:1007-22 ISHLT online registry www.ISHLT.com The Heart-Kidney Relationship in Heart Failure Dysfunction of one affects the other Increased load on the heart Decreased output from the heart Neurohormonal Activation Increased water & sodium retention Diminished blood flow to the kidney Neurohormonal Activation Impaired kidney function Poor absorption of drugs and drug delivery to kidney Ultrafiltration for Acute Heart Failure Mechanical removal of excess volume Safe and effective Patients on high dose diuretic (diuretic-resistance) Caution: Not a substitute for dialysis as waste products are not removed with this method Costanzo MR et al. JACC 2005;46:2047-2051. Clinical Trials at OSU: Measuring Pressures in the Heart Invasively for Heart Failure Management Left Atrial Pressure Sensor Modified PDA Powers through clothing Alerts patient to monitor ‘DynamicRX®’ calculates pressure and instructs patient on management RA LA Meds Activity Clinician contact Based on physician’s prescription for specific values obtained Measure pressures as an indication of fluid status Clinical Trials at OSU: Measuring Pressures in the Heart Invasively for Heart Failure Management 15 mm Measure pulmonary artery pressures for assessment of fluid No battery No leads Stem Cell Therapy and Heart Failure: Still being studied Sleep Apnea and Heart Failure People with heart failure have a high risk for sleep apnea If not treated, sleep apnea can cause: Drop in oxygen levels The heart rate to speed up A rise in the blood pressure Changes to the heart rhythm Stroke Heart attack or an episode of heart failure Normal breathing pattern Central sleep apnea: no breathing (apnea) alternates with rapid breathing Friends and Family Emotional support helps a patient have a more positive outlook on life Allow the patient to make decisions regarding health care and lifestyle behaviors Positive reinforcement Discuss fears about heart failure Discuss advanced care planning Don’t forget to take care of yourself: eat healthy, exercise, sleep Advanced Care Planning Not giving up Focus is on caring for the patient in a way that meets your wishes Key is communication Goal is to reduce stress on the patient Consists of Advanced care directive Do-not-resuscitate order Power of attorney Living will Financial plan Advanced Care Planning Palliative care Support program that focuses on comfort and reducing symptoms, pain. The disease is no longer responsive to curative treatment. Hospice care Support program for the patient and family through the dying process. Focus is also comfort and to help with bereavement. Nurses, chaplains, therapists, bereavement counselors, social workers and physicians Conclusion: Call your healthcare provider for these symptoms. . . A change in shortness of breath, fatigue, or swelling Requiring more pillows than usual to sleep comfortably at night or needing to sleep in a recliner Chest pain Near fainting or fainting Weight gain of 2 lbs in one day or 5 lbs in one week Conclusion: Living with Heart Failure See your physician regularly Weigh yourself daily & call your RN/MD if gaining Limit salt and fluid intake Exercise at a level recommended by your physician Avoid smoking Keep your flu and pneumonia vaccines current Take your medications Take an active role in managing your health! For More Information About Heart Failure… The Heart Failure Society of America via their website: Patients and caregivers– www.abouthf.org