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Nonpharmacologic Interventions in Pain Management Dan Wermeling, Pharm.D. Professor 225 COP Objectives Describe and apply physical approaches to pain treatment Describe psychological approaches used in pain treatment Describe alternative and complementary medicine approaches to pain treatment Attributes of Nonpharmacologic Pain Treatment Augment action of analgesic medications Stabilize mood, reduce anxiety Increase sense of self-control Strengthen coping abilities Improve sleep Relax muscles Enhance quality of life Sleep Hygiene – Non-restorative sleep makes pain and mood worse Keep regular schedule Exercise regularly away from sleep time Caffeine and alcohol management Manage bedroom activities for sleep only Eat last meal > 3 hours prior to sleep Physical Approaches to Pain Management General Goals – – Pain reduction Restoration of function Complement pharmacologic treatment Potentially decrease need for medications Cold Temperature Used acutely after physical injury Cold produces local anesthesia & slows nerve conduction Vasoconstriction, decreases inflammation Decreases swelling Examples Cold compress or ice pack – – Plastic bag & crushed ice Gel products – Reusable materials Rectangular packs or conforms to area of body injury, i.e., knee, shoulder, etc. Chemical cold – chemical reaction within container creates cold sensation, or chemical sprays – ether like evaporation. Usage Place over injured area Or, use rotational massage Sensations from burning, to mild ache, to numbing Avoid frostbite. Don’t over do. Look for white patchiness forming on skin to stop therapy. 20-30 minutes of each hour. Examples of Cold Products Heat Therapy Use after initial swelling is reduced Produces local analgesia Dilates blood vessels Promotes flexibility Relaxes muscles and decrease spasms Usage similar to ice packs Don’t over do. Can burn the skin Heat Products Physical Therapy Rest and immobilization – Exercises – Regain strength and range of motion Stretching – Promote injury healing Improve flexibility Massage – – Promote muscle relaxation and reduce pain Aromatherapy TENS Transcutaneous Electrical Nerve Stimulation A device applies a prescribed electrical impulse of low current across the skin Mechanism is defined within the gate theory – – – – Sends additional signals down nerve conduit Inhibition at the spinal level Promotes endogenous pain control (endorph) Restore afferent nerve input Muscle relaxation through tiring TENS TENS Uses Low back pain Neurogenic pain Musculoskeletal pain Post-surgical pain Patients adjust amplitude and frequency to optimize pain relief Relatively safe TENS Contraindications Use of other electrical devices, implanted pumps, pacemaker, etc. Pregnancy Sensory impaired area Near the throat, anterior neck Spinal Cord Stimulator Technology similar to TENS and Implanted Pump Pulse generator Gate Control Theory of Pain Principle Jerry Lewis (actor) Used for refractory pain, CRS, ischemia, failed back Psychological Approaches Cognitive Coping Strategy Relaxation with Imagery Biofeedback Hypnosis Contingency Management Psychotherapy Music Laughter Cognitive Goals are to alter the perceptions of pain Increase sense of control Decrease maladaptive behaviors Strategies Distraction – divert attention away from pain to a neutral or positive thought Relaxation and Imagery – – Attention is directed toward relaxing various muscle groups Imagine back toward a positive experience Coping – affirming positive outlook, like “ I can beat this”. Strategies Hypnosis – achieving an intense internal state of relaxation, almost trance like, at the suggestion to alter sensations, behavior, feelings or thoughts Problem solving – labeling a problem and creating solutions Acupuncture “rebalance body life force” Widely used Little data supporting efficacy Alternative and Complementary Approaches to Pain Management Definitions – – Alternative Medicine – used by themselves in place of traditional care Complementary – used in conjunction with traditional care Most common source is patients using “dietary supplements” – Arthritis, headaches, cancer uses Why do patients use these products? Dissatisfaction with contemporary medicine More consistent with health beliefs Effective treatment for headache, back ache, anxiety, emotional problems, etc. Consistent with prevention and wellness beliefs Concerns About These Therapies Potential side effects and drug interactions Variability in products potency and form No standardization Adulteration and contamination, nonGMP Active ingredient is unknown or a combination of unknowns Misidentification Costs are not insured Concerns Questions about claims made – – – Alter the structure and/or function of the human body, was, now disallowed Now they may not imply disease treatment or prevention Health maintenance claims allowed, like, “helps you maintain healthy bladder function” Consult FDA/NIH websites for specific information for consumer information Product Selection Quality Control Has product been evaluated in clinical studies and what were the results? Do the analyze raw materials and operate under GMP Does the company analyze product to make sure it matches label What are the bioavailability/dissolution standards? What are product contraindications? Examples and Comments Glucosamine – derived from shells. Has GI side effects. Can interact with diabetes and certain cancer treatments due to mechanism of action. May be efficacious in OA. Chondroitin – large glycoprotein in normal cartilage. Too large for oral absorption. Breakdown products have GI SE and edema. No drug interactions reported. Examples Devils Claw – root to treat joint pain. Acts as anti-inflammatory. Is oxytocin-like. Interacts with many medications, BP, cardiac, and is additive anti-coagulant with warfarin. – Cats Claw is similar Example Evening Primrose Oil – contains certain plant alkaloids – – – – Used in many pain treatments for diabetic neuropathy, PMS, mastitis, MS Metabolite blocks leukotriene metabolism Increased bleeding when used with other anticoagulant materials Seizures when combined with general anesthesia Conclusions There are many physical and psychological approaches available to supplement traditional pharmacotherapy These approaches are complementary in difficult cases and can make a difference Complementary and alternative approaches are used, but must be researched before implementation since they can have serious side effects.