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Transcript
Hardy-Weinberg Problems
1. In Drosophila (fruit fly), the allele for normal wing length is dominant over the allele for short wings. In a
population of 1000 individuals, 360 show the recessive phenotype. How many individuals would you expect to be
homozygous dominant for the trait?
2. The allele for a widow's peak (hairline) is dominant over the allele for a straight hairline. In a population of 500
individuals, 25% show the recessive phenotype. How many individuals would you expect to be homozygous
dominant and heterozygous for the trait?
3. The allele for a hitchhiker's thumb is dominant over a straight thumb. In a population of 1000 individuals, 510
show the dominant phenotype. How many individuals would you expect for each of the three possible genotypes
for this trait?
4. 1. If 9% of an African population is born with a severe form of sickle-cell anemia (ss), what percentage of the
population will be more resistant to malaria because they are heterozygous (Ss) for the sickle-cell gene?
5. After graduation, you and 19 friends build a raft, sail to a deserted island, and start a new population, totally
isolated from the world. Two of your friends carry (that is, are heterozygous for) the recessive cf allele, which in
homozygous recessive causes cystic fibrosis. Assuming that the frequency of this allele does not change as the
population grows, what will be the instance of cystic fibrosis on your island?
6. In Drosophilia, the allele for normal length wings is dominant over the allele for vestigial wings. In a population of
1,000 individuals, 360 show the recessive phenotype. How many individuals would you expect to be homozygous
dominant and heterozygous for this trait?
7. The allele for the ability to roll one's tongue is dominant over the allele for the lack of this ability. In a population
of 500 individuals, 25% show the recessive phenotype. How many individuals would you expect to be homozygous
dominant and heterozygous for this trait?
8. The allele for the hair pattern called "widow's peak" is dominant over the allele for no "widow's peak." In a
population of 1,000 individuals, 510 show the dominant phenotype. How many individuals would you expect of
each of the possible three genotypes for this trait?
9. In a certain population, the dominant phenotype of a certain trait occurs 91 % of the time. What is the frequency
of the dominant allele?
10. Calculate the allele frequencies for a population of the following numbers of individuals: 155 TT, 220 Tt, and
450 tt.