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Section 4.1.notebook December 03, 2010 Unit 2 - Reproduction Reproduction Role of Nucleus Asexual Reproduction Sexual Reproduction Nov 283:17 PM 1 Section 4.1.notebook December 03, 2010 Chapter 4 - The Nucleus Controls the Functions of Life Objectives: • Describe the role of the nucleus in controlling cell function, growth, and division • Distinguish between genes and chromosomes • Describe factors that may lead to changes in a cell's genetic information • Demonstrate an understanding of how mutations occur Section 4.1: The Function of the Nucleus within the Cell “Traits” are characteristics (or properties, or features) organisms have inherited from their parent(s)...like eye color, body chemistry, nose shape, etc. “Heredity” is the process of passing trait information onto the next generation. This involves copying your genetic material and placing it into new cells. “Genetics” is the study of heredity. Nov 283:39 PM 2 Section 4.1.notebook December 03, 2010 Main Parts of a Cell • Nucleus • Cell membrane/wall • Cytoplasm • Mitochondria These are called organelles. There are two groups of cells (you are not responsible to know this) Prokaryotic cells - their genetic material is often a ring ( a “plasmid”) of a molecule called RNA found somewhere in the cell cytoplasm. Considered older, simpler, and more ancient cell species than... Eukaryotic cells - have DNA molecules inside their nucleus ( “chromatin” spread out tangled DNA.... “chromosomes”...coiled, tightened X- shaped bundles of DNA) Nov 283:40 PM 3 Section 4.1.notebook December 03, 2010 In eukaryotic cells, it is the nucleus that controls the day to day activities of the cell: • • • • • • obtain nutrients change these nutrients into energy grow repair themselves reproduce get rid of waste The nucleus contains the master set of instructions that decides how a cell works, when it will grow, when to reproduce, and when to die. The instructions in the nucleus are carried in long, twostranded molecules called DNA ( deoxyribonucleic acid ). The DNA molecule is a double helix (looks like a twisted ladder). It is the molecule where your genetic information. DNA‛s instructions guide the cell‛s day to day workings, and controls the cell‛s reproduction. Chromosome Chromosome Spreadout tangled DNA called chromatin DNA double helix twisted ladder DNA double helix twisted ladder Centromere Centromere unreplicated chromosome chromosome Can only see chromosomes when a cell is ready to divide or reproduce. Nov 284:28 PM 4 Section 4.1.notebook December 03, 2010 Extra Information - you are not responsible for this (DNA structure)....the “double helix”....shaped like a twisted ladder - phosphate and sugars make up the two sides - pairs of shape matching “nitrogen base” make up the middle steps C matches with G A matches with T The order ( sequence ) of A‛s, C‛s, T‛s, and G‛s are recipes that tell the cell how to make protein molecules. Nov 285:09 PM 5 Section 4.1.notebook December 03, 2010 Most of the time, DNA exists in the nucleus in a loosely coiled form. When a cell is growing, the DNA is uncoiled and aids in the manufacture of proteins. Proteins are essential materials required for the cell to carry out activities necessary for survival. When a cell is ready to divide, each strand of loosely coiled DNA folds up further into a compact, X-shaped structure called a chromosome. Spreadout tangled DNA in the nucleus, which is called chromatin, tightens Centromere into a compact coil. unreplicated chromosome chromosome Chromosomes within the nucleus are found in pairs. Most human cells have 23 pairs of chromosomes (i.e. 46 chromosones) including one pair that determines gender. Different species have different numbers of chromosomes in their cells. ( pg 117). In sex cells, the number of chromosomes is half, to 23, so that when sperm and egg combine, the embryo produced has the correct number of 46 chromosomes. Genes • Found on chromosomes. • Small segments of DNA located at specific places on a chromosome. • Store information needed to produce 90 000 to 100 000 proteins used by body cells. Dec 112:39 PM 6 Section 4.1.notebook December 03, 2010 • Genes can vary in length from hundreds to thousands of bases. • The arrangement of bases will determine the protein produced. • Each chromosome contains thousands of genes and therefore contains the information to make thousands of different proteins. • Proteins determine what body cells will become and how they will function. • Specialize cells will form tissues; tissues will form organs. Only specific genes are read in each cell to produce specific proteins. By making specific proteins, a cell becomes specialized to carry out a specific function. (Read “Wild, Weird, and Wonderful”, page 120) Dec 19:56 PM 7