Survey
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Orthohantavirus wikipedia , lookup
Foot-and-mouth disease wikipedia , lookup
Taura syndrome wikipedia , lookup
Human cytomegalovirus wikipedia , lookup
Canine distemper wikipedia , lookup
Canine parvovirus wikipedia , lookup
Marburg virus disease wikipedia , lookup
Hepatitis B wikipedia , lookup
Activities in 2009 Infectious bovine rhinotracheitis/ Infectious pustular vulvovagenitis Dr Malcolm Banks Veterinary Laboratories Agency, Addlestone, Surrey, UK, KT15 3NB, UK Tel.: +44 (0)1932 357509, Fax: +44 (0) 1932 357239 [email protected] Summary of general activities related to the disease 1. 2. Test(s) in use/or available for the specified disease at your laboratory Test For Specificity Total iELISA Antibody Whole virus 9260 cELISA Antibody gB 9697 cELISA Antibody gE 89 Bulk Milk iELISA Antibody Whole virus 1219 Individual Milk iELISA Antibody Whole virus 27 VN Antibody 24 hour 104 FAT Antigen BoHV-1 3380 BHK-21 cell culture Virus isolation BoHV-1 2 Real-Time PCR DNA in semen BoHV-1 0 Production and distribution of diagnostic reagents Diagnostic reagents are prepared both for regional laboratories nationally, and for other countries. Materials supplied include known positive and negative sera for use as test controls, FITC conjugated antiserum for viral antigen detection, prepared positive and negative control slides for FAT, positive and negative semen samples for the PCR and antigen for use in ELISA tests. Individual freeze dried BHV-1 strains are also supplied on request. Activities specifically related to the mandate of OIE Reference Laboratories 3. International harmonisation and standardisation of methods for diagnostic testing or the production and testing of vaccines The VLA conducts national and international proficiency testing for IBR assays. The following proficiency tests are carried out for laboratories in the following countries: Annual reports of OIE Reference Laboratories and Collaborating Centres, 2009 1 Infectious bovine rhinotracheitis/infectious pustular vulvovaginitis IBR Serum ELISA PT is carried out 4 times annually for laboratories in Czech Republic (2), Austria, UK (5) Spain, S. Africa, Slovenia, Latvia, Italy, Portugal and The Netherlands. IBR Milk ELISA PT is carried out 4 times annually for laboratories in UK (3), Austria, Norway and Czech Republic IBR PT is carried out twice annually as part of a bovine respiratory virus package (IBR/RSV/PI3) serology PT for laboratories in Czech Republic, UK (5) Italy, Portugal and The Netherlands 4. Preparation and supply of international reference standards for diagnostic tests or vaccines A replacement for EU 1 and EU 2 has been prepared. 5. Research and development of new procedures for diagnosis and control Work to examine the feasibility of multiplexing IBR diagnosis with other common bovine respiratory pathogens is ongoing 6. Collection, analysis and dissemination of epizootiological data relevant to international disease control An investigation has been funded by the VLA into an outbreak of IPB at a UK bull stud. It is anticipated this investigation, which will report in 2010, will provide data relating inter alia, on semen excretion patterns in bulls infected with BoHV-1. 7. Provision of consultant expertise to OIE or to OIE Members Consultant advice has been given, on request, to workers in Greece, India, Chile, Argentina, Egypt and USA. Advice on IBR outbreak management and control has been provided by the designated expert to 2 bull studs in the UK 8. Provision of scientific and technical training to personnel from other OIE Members None 9. Provision of diagnostic testing facilities to other OIE Members Diagnostic facilities were provided for a dairy cattle organisation in the Republic of Ireland 10. Organisation of international scientific meetings on behalf of OIE or other international bodies None 11. Participation in international scientific collaborative studies None 2 Annual reports of OIE Reference Laboratories and Collaborating Centres, 2009 Infectious bovine rhinotracheitis/infectious pustular vulvovaginitis 12. Publication and dissemination of information relevant to the work of OIE (including list of scientific publications, internet publishing activities, presentations at international conferences) Presentations at international conferences and meetings None Scientific publications in peer-reviewed journals None Other communications A presentation on IBR diagnosis and control was given by the designated expert to UK cattle breeding companies and regulatory officials 13. Inscription of diagnostic kits on the OIE Register i) Did you participate in expert panels for the validation of candidate kits for inscription on the OIE Register? If yes, for which kits? No ii) Did you submit to the OIE candidate kits for inscription on the OIE Register? If yes, for which kits? No _______________ Annual reports of OIE Reference Laboratories and Collaborating Centres, 2009 3