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2/16/12 Scaling up: from tissue structure to system and organism structure Learning Objectives Explain the division of the body in terms of positional references, sectional planes, cavities, regions and quadrants Establish a working definition of an organ and identify the major organ systems and their functions Anatomical detail GROSS Describe surface shape, orientation And relative position MICRO Describe with the aid of the microscope fine structural detail to cellular level Appreciate the information exchange requirements needed for organs to work together systematically Develop an understanding of multiple organ system cooperation in homeostatic control The Anatomical Position Anatomical Directional References Standard illustrations show the human form in the following position: -hands at sides -palms forward -feet together FRONT VIEW=ANTERIOR REAR VIEW=POSTERIOR If lying down & anterior aspect up =SUPINE If lying down & posterior aspect up =PRONE Fundamentals of Anatomy & Physiology 7th Ed. 1 2/16/12 Sectional Planes Frontal also known as coronal Sagittal cut parallel to midline known as parasagittal Abdominopelvic Quadrants and Regions Anatomical Regions Area Head Neck Chest Arm Forearm Wrist Hand Abdomen Loin Buttock Pelvis Region Cephalic Cervical Thoracic Brachial Antebrachial Carpal Manual Abdominal Lumbar Gluteal Pelvic Area Anterior Pelvis Groin Thigh Anterior leg Calf Ankle Foot Sole Region Pubic Inguinal Femoral Crucal Sural Tursal Pedal Plantar Organs are suspended inside chambers termed cavities Protection and room for expansion Dashed lines delineate upper and lower,right and left quadrants N.B. Although the kidney and pancreas are in the abdominal cavity they lie behind the peritoneum and are thus described as retroperitoneal 2 2/16/12 Organs and Organ Systems Organ 2 or more tissues, generally combined in a discrete unit specialised to perform a particular function. e.g) the heart Organ System Co-ordinated physical and chemical interactions between discrete organs/tissues to deliver a systemic function. e.g) the cardiovascular system (heart-blood vessels-blood) System Integration Anatomical/functional co-dependency and cross-regulation between organ systems. Key to whole body homeostasis. e.g.) cardiovascular system & urinary system regulate fluid balance Some Commonalities in Organs Requirement for perfusion (nutrient in/waste out/blood borne secretions out Penetration by cardiovascular system Penetration by lymphatic system Integration with digestive and urinary systems Requirement for input control and feedback Penetration by nervous system Penetration by cardiovascular system (endocrine communication) Requirement for infection surveillance Penetration by cardiovascular system Penetration by lymphatic system N.B. Perturbation of one organ system can initiate a cascade of disturbances in other organ systems The Eleven Organ Systems • • • • • • • • • • • Integumentary Muscular (Skeletal) Skeletal Nervous Endocrine Circulatory Immune Respiratory Digestive Urinary Reproductive coordinated function Dynamic control of internal environment The Integumentary System Major Components Skin Hair Sweat glands Nails Functions Protective barrier Body temperature regulation Sensory input Synthesis of Vitamin D 3 2/16/12 The Skeletal System The Muscular (Skeletal) System Major Components Bone Cartilage Marrow Major Components Skeletal muscle fibres Tendons Functions Support Protection Calcium storage Synthesis of blood cell precursors Functions Support Protection Movement Thermoregulation The Nervous System Major Components Brain Spinal cord Peripheral nerves Sensory organs Functions Coordination of activity Consciousness The Endocrine System Major Components Pituitary gland Thyroid gland Parathyroids Pancreas Adrenal gland Gonads Adipose tissue Functions Long term regulation of function Control of metabolism Developmental change 4 2/16/12 The Circulatory System Major Components Cardiovascular system Heart Blood Vasculature Lymphatic system Lymphatic vessels Lymph nodes Functions Distribution of dissolved and suspended material Interstitial fluid recirculation Immune cell trafficking Thermoregulation The Respiratory System Major Components Nasal cavity Sinuses Larynx Trachea Bronchi Lungs Functions Gas exchange Generation of sound The Immune System Major Components Spleen Thymus Lymphatic vessels Lymph nodes Functions Infection surveillance The Digestive System Major Components Oral cavity and teeth Tongue Pharynx Oesophagus Stomach Small Intestine Large intestine Liver Gallbladder Pancreas Functions Digestion Absorption Excretion Storage of nutrients 5 2/16/12 The Reproductive System The Urinary System Major Components Kidneys Ureters Bladder Urethra Functions Excretion Regulation of blood pH Regulation of ECF volume Regulation of erythropoesis Vitamin synthesis Major Components Male Testes and scrotum Epididymis Vas deferens Seminal vesicles Prostate gland Penis Female Ovaries Fallopian tubes Uterus Vagina (Mammary glands) Functions Male Testosterone synthesis Spermatazoa production Copulation Female Progesterone & oestrogen synthesis Oocyte generation Copulation Gestation of foetus Lactation Plasma Calcium Homeostasis Involves Interaction of all The Following Systems -SKIN -ENDOCRINE -BONE -GASTROINTESTINAL -URINARY Refer to text in red on previous slides and then try to put together the story from your physiology textbook 6