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Food Valley Expo
Personalizing dairy protein for different target groups
Urszula Kudla
13 October 2016
Is there an option for semipersonalized
nutrition?
Sporters
Specific group with defined
nutritional needs
Infants & Kids
We already have highly
personalized propositions –
especially for the youngest
ones
Seniors
Specific group with very
specific nutritional needs
Adults
Too vague – not really a
group
1
Why focus on muscle?
30
Age (y)
60
● WHO/HPS (2000)
Why focus on muscle?
● Mobility
• ADL (independence)
• Sports (lifestyle & performance)
● Metabolic health
• Skeletal muscle (40% of BW, 70% of energy
expenditure)
• Clearance of nutrients from bloodstream
● Associations:
• Stronger people live longer
(Newman et al. 2006)
• Have less T2D, CVD, even cancer
• Osteoporosis?
(Ruiz et al 2008)
Why protein and muscle?
•
Essential amino acids from proteins are
the primary building blocks for muscle
(20% of muscle, 80% of muscle DM)
•
It takes only 3 months to completely
renew skeletal muscle
•
Muscle protein synthesis is stimulated
by protein intake and exercise
•
Dairy protein is highly digestible with
excellent amino acid profile
4
Burd et al, J App. Phys, 2009
Is there a need for personalizing protein
intake to improve muscle health?
Amount
0.8 g protein/kg bodyweight/day, also for
elderly subjects
Timing
Type
Considerable scientific debate.
National recommendations changed in
Nordic countries and France.
EUGMS, ESPEN, protein summit: 1 –
1.2g/kg BW for seniors
ACSM 0.8 – 1.7 g/kg bw for sporters
Amount: Evidence from intervention
studies
Amount
Moore et al, AJCN, 2009; Yang et al, Br J Nutr, 2012
Macnaughton et al, AJCN, 2016
Muscle protein synthesis is a saturable process; optimal dose 20-25g for
young and up to 40g for elderly.
40g of whey have been shown to have better effect in the latest study
Timing: After exercise
Timing
● Meta analysis: Protein intake after resistance exercise increases
muscle mass in younger and older subjects
Cermak et al, AJCN, 2012
Timing: Before sleep
Chronic effect
Timing
Mass
Acute effect
Strength
Res et al, Med Sci. Sports Exerc 2012
Snijders et al, Journal of Nutrition 2015
Timing: Throughout the day - Seniors
Change in le an body mass (kg)
Timing
2.0
Placebo
Protein
1.5
1.0
0.5
0.0
-0.5
-1.0
12
24
Time (wks)
•
•
•
40% increase in strength
20% in physical functioning
1.3 kg muscle mass
Tieland et al 2012,
•
Without protein apparent loss of
muscle mass
ProMuscle is a road towards seniors vitality and better healthcare
Movie
Timing: From ProMuscle to ProMuscle in
practice
Timing
11
Partnerships: Co-creation to nourish seniors for
better future!
Does balanced distribution throughout the day
work for young subjects?
Timing
Effect of different ingestion patterns of 80g of protein during
12h recovery after resistance exercise:
Bolus: 2 x 40g
Intermediate: 4 x 20g
Pulse: 8 x 10g
Areta et al, J Physiol, 2013
Protein intake, sources and mealtime distribution
of Dutch elite athletes
Timing
The Dutch Sport Nutrition and Supplement Study (DSSS) cohort
- 553 elite athletes
- 71 strength athletes
- 242 team athletes
- 240 endurance athletes
- 24-h dietary recalls
Athletes typically consume well above 1.2 g protein/kg/d with their normal
diet.
Gillen et al, unpublished,
Protein intake, sources and mealtime distribution
of Dutch elite athletes
Timing
Strength
Team
Endurance
A large proportion of Dutch elite athletes is not meeting the advised 20 g of protein
intake during breakfast. This is more pronounced for women than for men.
Gillen et al, unpublished,
Type: Not all proteins were created
equal
Type
Leucine is considered to a key amino acid, which is likely the
main reason why whey protein is so effective
Van Vliet et al, J Nutr, 2015
Effect of 12 weeks of exercise
Hartman et al, J Nutr, 2007
16
Type: of exercise also matters
Type
• Resistance exercise stimulates primarily the myofibrillar
protein synthesis
• Endurance Exercise stimulates to a greater extent the
mitochondrial protein synthesis
• Synthesis of myofibrillar and mito protein differs in
time
Effect of 10 weeks of exercise
Wilkinson et al, J Physiol, 2008
17
Conclusions
• It matters how much protein you eat, and seniors as
well as athletes need more protein than 0.8g /kg BM
Amount
• Strong muscles are essential for maintaining quality
of life and physical independence in older age
Timing
• It matters when you eat protein: after exercise,
breakfast, lunch and before sleep
Type
• Protein quality matters!
• Endurance exercise needs to be explored
18
Thank you
19