
Lack of Knowledge on the Use and Benefits of Creatine
... from its use, the optimal dosage for an individual, and the effects of creatine, particularly any long term effects that may stem from its use. Scientific Basis of Creatine Supplementation (PG) As mentioned earlier, creatine could be known as a muscle enhancer on the basis of performance. It is quit ...
... from its use, the optimal dosage for an individual, and the effects of creatine, particularly any long term effects that may stem from its use. Scientific Basis of Creatine Supplementation (PG) As mentioned earlier, creatine could be known as a muscle enhancer on the basis of performance. It is quit ...
Creatine supplementation with specific view to exercise/sports
... protein and carbohydrate compared with protein alone or a protein carbohydrate supplement without the creatine. These findings were novel because at the time no other research had noted such improvements in body composition at the cellular and sub cellular level in resistance trained participants su ...
... protein and carbohydrate compared with protein alone or a protein carbohydrate supplement without the creatine. These findings were novel because at the time no other research had noted such improvements in body composition at the cellular and sub cellular level in resistance trained participants su ...
Creatine - Creighton Prep
... The absorption of creatine in the muscle is influenced by sodium and insulin. In this regard, sodium serves as a co-transporter of creatine into muscle tissue and muscle creatine uptake is enhanced when insulin levels are high. For this reason, it is recommended to ingest creatine with a glucose dri ...
... The absorption of creatine in the muscle is influenced by sodium and insulin. In this regard, sodium serves as a co-transporter of creatine into muscle tissue and muscle creatine uptake is enhanced when insulin levels are high. For this reason, it is recommended to ingest creatine with a glucose dri ...
Glycogen branches out: new perspectives on the role of glycogen
... synthase knockout mouse model correlated with a robust increase in AMPK phosphorylation state (44). AMPK has been shown to directly bind glycogen (48), but because glycogen addition did not affect AMPK activity in vitro (48), the significance of this interaction may be at the level of subcellular lo ...
... synthase knockout mouse model correlated with a robust increase in AMPK phosphorylation state (44). AMPK has been shown to directly bind glycogen (48), but because glycogen addition did not affect AMPK activity in vitro (48), the significance of this interaction may be at the level of subcellular lo ...
(Book) Creatine: Increasing Sports Performance
... the 1970s, to power their Olympic athletes, but neither I, nor those in the creatine field of research that I have discussed this with, have found any scientific documentation of this. A few former Soviet athletes may have mentioned that they were fed creatine phosphate or were given creatine phosph ...
... the 1970s, to power their Olympic athletes, but neither I, nor those in the creatine field of research that I have discussed this with, have found any scientific documentation of this. A few former Soviet athletes may have mentioned that they were fed creatine phosphate or were given creatine phosph ...
The metabolic responses of high intensity intermittent exercise in
... effect of interspersed work and passive rest. Although the aforementioned studies were training studies, this study used single bouts of workload matched HIIE and moderate intensity, continuous exercise (CON) and found similar levels of fat utilisation between the two trials as well as significantly ...
... effect of interspersed work and passive rest. Although the aforementioned studies were training studies, this study used single bouts of workload matched HIIE and moderate intensity, continuous exercise (CON) and found similar levels of fat utilisation between the two trials as well as significantly ...
Creatine A Complete Users Guide
... You will also see AKG used with other supplements to act in a similar manner. Pro: enhanced absorption rate Con: more expensive form of creatine Micronised Creatine: This is a finer powdered version of creatine monohydrate. Pro: less chances of gastrointestinal problems is available in more and more ...
... You will also see AKG used with other supplements to act in a similar manner. Pro: enhanced absorption rate Con: more expensive form of creatine Micronised Creatine: This is a finer powdered version of creatine monohydrate. Pro: less chances of gastrointestinal problems is available in more and more ...
fiber types in mammalian skeletal muscles
... unique fiber types have been identified, as discussed below. Clearly, a large number of proteins are differentially expressed in the various muscle fiber types, and it has been proposed that the simple classification based on myosin composition and level of oxidative enzymes is only convenient for c ...
... unique fiber types have been identified, as discussed below. Clearly, a large number of proteins are differentially expressed in the various muscle fiber types, and it has been proposed that the simple classification based on myosin composition and level of oxidative enzymes is only convenient for c ...
fiber types in mammalian skeletal muscles
... of fast-twitch muscles, characterized by glycolytic metabolism and specialized for phasic activity, generally identified with white muscles, and slow-twitch muscles, rich in myoglobin and oxidative enzymes and specialized for more continuous activity, also called red muscles (562). The mechanical an ...
... of fast-twitch muscles, characterized by glycolytic metabolism and specialized for phasic activity, generally identified with white muscles, and slow-twitch muscles, rich in myoglobin and oxidative enzymes and specialized for more continuous activity, also called red muscles (562). The mechanical an ...
Influence of nutritional interventions to optimise fat metabolism and
... There are a number of people I would like to thank who have made this PhD thesis possible. First and foremost I would like to start by thanking Professor Asker Jeukendrup for allowing me to complete a PhD within the school. I have learnt a great deal from you Asker. The drive, ambition and passion t ...
... There are a number of people I would like to thank who have made this PhD thesis possible. First and foremost I would like to start by thanking Professor Asker Jeukendrup for allowing me to complete a PhD within the school. I have learnt a great deal from you Asker. The drive, ambition and passion t ...
NSCA`s Guide to Sport and Exercise Nutrition
... What is sport nutrition? Ask 10 different people this question, and you are likely to receive 10 different answers. At its most basic level, sport nutrition is the practice of ingesting nutrients in the correct amounts at specific times to improve exercise or sport performance. But while improving s ...
... What is sport nutrition? Ask 10 different people this question, and you are likely to receive 10 different answers. At its most basic level, sport nutrition is the practice of ingesting nutrients in the correct amounts at specific times to improve exercise or sport performance. But while improving s ...
- Opus
... lumen into the enterocyte [23]. Other putative routes include transport by glucose transporter 2 (GLUT2) and GLUT12, although these are yet to be clearly established in humans [24], and are likely to play only minor roles in intestinal glucose absorption [23]. Whilst fructo ...
... lumen into the enterocyte [23]. Other putative routes include transport by glucose transporter 2 (GLUT2) and GLUT12, although these are yet to be clearly established in humans [24], and are likely to play only minor roles in intestinal glucose absorption [23]. Whilst fructo ...
COLOSTRUM AS NUTRITIONAL SUPPLEMENT – Journal Of
... supplement for increase levels for IGF-1 concentration (Mero et al., 1997). This compound IGF-1 (insulin-like growth factor) is an anabolic hormone and could be used as supplement, but is banned by the International Olympic Committee. Thus, if the athletes will take colostrums as ergogenic supplemen ...
... supplement for increase levels for IGF-1 concentration (Mero et al., 1997). This compound IGF-1 (insulin-like growth factor) is an anabolic hormone and could be used as supplement, but is banned by the International Olympic Committee. Thus, if the athletes will take colostrums as ergogenic supplemen ...
Product Data Sheet Your assurance of quality®
... muscles. ATP is the body’s major molecule that produces “explosive” chemical energy within cells and is also known as “molecular currency.” Approximately 95% of the total body pool of creatine is found in muscles and provides the source of energy for all cellular functions including muscle contracti ...
... muscles. ATP is the body’s major molecule that produces “explosive” chemical energy within cells and is also known as “molecular currency.” Approximately 95% of the total body pool of creatine is found in muscles and provides the source of energy for all cellular functions including muscle contracti ...
Product Data Sheet
... into the muscle cells by providing a transport vehicle by it’s unique ability to mimic insulin. L-Taurine is a non-essential sulfur containing amino acid with high concentrations found in skeletal muscles and appears to play a role in cellular defenses (cytoprotective) including DNA damage from free ...
... into the muscle cells by providing a transport vehicle by it’s unique ability to mimic insulin. L-Taurine is a non-essential sulfur containing amino acid with high concentrations found in skeletal muscles and appears to play a role in cellular defenses (cytoprotective) including DNA damage from free ...
CX3 creatine
... Creatine phosphate is predominantly used in Type II (fast twitch) fibers and is the major fuel source for high intensity exercise. Many published studies indicate that creatine supplementation increases total body mass. The increase in body weight has been theorized to be the result of creatine-stim ...
... Creatine phosphate is predominantly used in Type II (fast twitch) fibers and is the major fuel source for high intensity exercise. Many published studies indicate that creatine supplementation increases total body mass. The increase in body weight has been theorized to be the result of creatine-stim ...
Beta-alanine Supplementation
... Effects of Beta-alanine on Neuromuscular Fatigue and Ventilatory Threshold in Women 22 normal-weight women (ages 26 to 29 years) were subjects in a 4 week beta-alanine supplementation trial Dose of beta-alanine or placebo (maltodextrin) was 800 mg 4 times/day for the first week, and 1,600 mg 4 ...
... Effects of Beta-alanine on Neuromuscular Fatigue and Ventilatory Threshold in Women 22 normal-weight women (ages 26 to 29 years) were subjects in a 4 week beta-alanine supplementation trial Dose of beta-alanine or placebo (maltodextrin) was 800 mg 4 times/day for the first week, and 1,600 mg 4 ...
Mechanisms underlying inhibition of muscle disuse
... oxidative stress, energy metabolism, the cell stress response, cell death and survival and epigenetic modification. In particular, the expression levels of genes encoding cell cycle regulatory-, pro-survival and chromatin remodelling proteins, such as serine/threonine-protein kinase Chk1, cell divis ...
... oxidative stress, energy metabolism, the cell stress response, cell death and survival and epigenetic modification. In particular, the expression levels of genes encoding cell cycle regulatory-, pro-survival and chromatin remodelling proteins, such as serine/threonine-protein kinase Chk1, cell divis ...
GLYCOGENOLYSIS AND GLYCOLYSIS IN MUSCLE
... amounts of starch are very useful to us as foodstuffs. Plants also link glucose molecules together in a complex pattern to form cellulose for structural purposes, but humans lack the enzymes necessary to digest this glucose polymer. There are numerous dietary sources of glucose, including starches, ...
... amounts of starch are very useful to us as foodstuffs. Plants also link glucose molecules together in a complex pattern to form cellulose for structural purposes, but humans lack the enzymes necessary to digest this glucose polymer. There are numerous dietary sources of glucose, including starches, ...
Kemiko`s Megastar (Cretine Monohydrate) 1st time Bangladesh
... as a waste product called creatinine. If you constantly overdose Creatine (>20 g/day) - you will have increased waste of creatinine. This constant excretion of creatinine may put extra stress on your kidneys and liver, as well as lead to gastro-intestinal discomfort. Creatine is an osmotically activ ...
... as a waste product called creatinine. If you constantly overdose Creatine (>20 g/day) - you will have increased waste of creatinine. This constant excretion of creatinine may put extra stress on your kidneys and liver, as well as lead to gastro-intestinal discomfort. Creatine is an osmotically activ ...
Regulation of Skeletal Muscle Physiology and Metabolism by
... PPARs are predominantly nuclear and regulate transcription by heterodimerizing with the retinoid X receptor (RXR) as shown in Fig. 1. The receptor complex binds to a peroxisomal proliferator response element (PPRE) located in the regulatory region of a gene and binds to DNA in the absence of ligands ...
... PPARs are predominantly nuclear and regulate transcription by heterodimerizing with the retinoid X receptor (RXR) as shown in Fig. 1. The receptor complex binds to a peroxisomal proliferator response element (PPRE) located in the regulatory region of a gene and binds to DNA in the absence of ligands ...
Ca2+-Dependent Regulations and Signaling in Skeletal Muscle
... transmembrane protein in the SR-membrane and its EF-hand domain is located in the lumen of the SR where it is able to sense changes in Ca2+ store content. The coiled-coil domains located in the cytosolic part are believed to interact with Orai1, a tetrameric ion channel complex which facilitates inc ...
... transmembrane protein in the SR-membrane and its EF-hand domain is located in the lumen of the SR where it is able to sense changes in Ca2+ store content. The coiled-coil domains located in the cytosolic part are believed to interact with Orai1, a tetrameric ion channel complex which facilitates inc ...
proudly presented by… - Creatine Information Center
... body with an overload of creatine. In this respect, certain issues confront any aspiring creatine manufacturer: (1) creatine’s low solubility in water; (2) muscle’s limited capacity to transport creatine; and (3) how to effectively combine creatine with other nutritional supplements for the best eff ...
... body with an overload of creatine. In this respect, certain issues confront any aspiring creatine manufacturer: (1) creatine’s low solubility in water; (2) muscle’s limited capacity to transport creatine; and (3) how to effectively combine creatine with other nutritional supplements for the best eff ...
Heriot-Watt University The effect of sodium acetate ingestion on the
... The Effect of Sodium Acetate Ingestion on the Metabolic Response to Prolonged Moderate-Intensity Exercise in Humans Gordon I. Smith, Asker E. Jeukendrup, and Derek Ball At rest, administration of the short-chain fatty acid acetate suppresses fat oxidation without affecting carbohydrate utilization. ...
... The Effect of Sodium Acetate Ingestion on the Metabolic Response to Prolonged Moderate-Intensity Exercise in Humans Gordon I. Smith, Asker E. Jeukendrup, and Derek Ball At rest, administration of the short-chain fatty acid acetate suppresses fat oxidation without affecting carbohydrate utilization. ...
Beta-Hydroxy beta-methylbutyric acid

Beta-Hydroxy beta-methylbutyric acid β-Hydroxy β-methylbutyric acid (HMB), or β-hydroxy β-methylbutyrate, is a metabolite of the essential amino acid leucine and is synthesized in the human body. Its part in protein synthesis was discovered by Steven L. Nissen at Iowa State University. It has been used in scientific studies to purportedly increase muscle mass and decrease muscle breakdown. Nissen held the original patent on the metabolite as a nutritional supplement. It was discovered in pigs and small quantities can also be found in grapefruit, alfalfa, and catfish. As a supplement it is usually sold as the calcium salt calcium beta-hydroxy-beta-methylbutyrate.Research published in the Journal of Applied Physiology has shown that HMB may have an effect on increasing muscle weight and strength. A review in Nutrition & Metabolism provides an in depth and objective analysis of HMB research.The same study lists as HMB's proposed mechanisms of action the following: Increased sarcolemmal integrity via conversion to HMG-CoA Enhanced protein synthesis via the mTOR pathway Depression of protein degradation through inhibition of the ubiquitin pathwayThe human body produces about 0.2-0.4 grams per day. Standard doses in research studies have been 1.5 to 3.0 grams per day, usually divided into two doses. Toxicity at these doses is unlikely, as the no-observed-adverse-event-level (NOAEL) in rats is between 2.48 to 2.83 g/kg BW per day, roughly equivalent to 70 to 100 g/day in humans.