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Body Systems Overview Mark Olson, Ph.D., LMT Some Terms • Anatomy: Study of gross structures of body • Physiology: Study of bodily functions • Histology: Study of tissues • Pathology: Study of conditions of disease or dysfunction • Kinesiology: Study of motion o Structural = origins, insertions, actions of muscles o Applied = resisted muscle testing for assessment • Palpation: Tactile observation (with hands) of body structures and tissues • Medical terminology: (Prefix + Root) OR (Root + Suffix) Anatomical Position • Body standing, erect. Feet flat and slightly apart • Arms down by side • Palms facing forward, so thumbs point away from body Planes and Directions (tg 29, c 1-2) • Body Planes o Sagittal, Mid-sagittal o Frontal, Coronal o Transverse, Horizontal • Directions o Medial / Lateral o Proximal / Distal (extremities) o Superficial / Deep o Posterior / Anterior o *Dorsal / Ventral (same as Post/Ant below head) o Superior / Inferior (4 vs 2 leg) o *Rostral (nose) / Caudal (tail) Or Cranial (head) / Caudal At trunk, Rostral = Superior. Anterior = Ventral At front of head, Rostral = Anterior. Ventral = Inferior o Ipsilateral / Contralateral Body Cavities (c 7) • Dorsal cavity o Protects the nervous system o Two subdivisions Cranial cavity (brain) Spinal cavity (spinal cord) • Ventral cavity o Houses the internal organs (viscera, or “gut”) o Two subdivisions divided by diaphragm Thoracic (heart and lungs) Abdominopelvic • Abdominal (stomach, liver, pancreas, intestines) • Pelvic (bladder and reproductive organs) Cells (c 8) • Fundamental unit of all living things. Maintain life via metabolism • 75 trillion (75,000,000,000,000) • 216 cell types • Parts: Membrane (protection/absorption), Nucleus (contains DNA), Cytoplasm (cell fluid), Mitochondria (creates ATP/energy), Lysosome (recycler), Ribosome, Golgi Apparatus, Endoplasmic reticulum (rough and smooth: converts DNA code into protein) • Replicate via Mitosis (cell division) Tissues (c 17) • A group of cells performing the same function • 4 types o Epithelial (c 10) o Connective (c 11-12) o Muscle (c 13) o Nervous (c 15) Epithelial Tissue • Covers exposed parts of body (separates in from out) • Lines many internal passages • Qualities • Cells tight together • Polarity: exposed and attached surfaces (connective tissue) • Avascular • Innervated • Regeneration • Functions • Protection • Absorption • Secretion • Sensation • Conservation of body heat Epithelial Membranes • Serous: Simple squamous. Line and cover organs of ventral cavity.3 types: pleura, pericardium, peritoneum • Mucous: Lines the digestive, respiratory, reproductive, and urinary systems. Secretes mucus • Cutaneous (skin): Stratified squamous • Thick membrane composed of several layers of cells • Function in protection of underlying areas subjected to abrasion • Forms the external part of the skin’s epidermis, and linings of the esophagus, mouth, and vagina Glandular Epithelia • Endocrine secretions • Hormones secreted into interstitial fluid and blood • Produced in endocrine glands (ductless) • Regulate, coordinate activities of other tissues and organs • Exocrine secretions • Discharged onto skin or other epithelial tissues • Released via ducts • Ex: digestive enzymes, mammary milk, sweat, saliva, mucus, tears, etc Connective Tissue • Produces extracellular material consisting of fibers embedded in ground substance. • Binds, supports and protects body parts • Vascular • Cells are found within supportive non-living matrix of fibers • Functions o Support o Protection o Transport o Energy Storage o Defense Structural Elements of Connective Tissue • Ground substance – unstructured material, secreted by cells, that fills the space between cells • Fibers – collagen, elastic, or reticular • Cells – fibroblasts, chondroblasts, osteoblasts, and hematopoietic stem cells Connective Tissue Types • Loose Connective Tissue – Provides strength, flexibility, and packing material – Adipose Tissue: contains large number of fat cells, which cushions, insulates, and stores energy • Dense/Fibrous Connective Tissue – Is tough and strong. Dominated by collagen fibers – Makes up tendons and ligaments, capsules that surround organs and joint cavities • Supporting Connective Tissue – Makes up bone and cartilage. • Fluid Connective Tissue – Lymph—interstitial fluid escaping from tissues returned to blood vessels via lymphatic vessels. – Blood consists of watery plasma and blood cells; three main types of blood cells: Muscle Tissue • Contractile tissue produces movement of/within the body • Vascular • Types o Skeletal (striated, voluntary): attach to bones or skin o Cardiac (striated, nonvoluntary): heart only o Smooth (nonstriated, nonvoluntary)—walls of hollow organs: blood vessels, air passages, visceral organs. • Striated vs. nonstriated • Voluntary vs. non-voluntary Nervous Tissue • Neurons—Transmit nerve signals o Cell bodies, axons, dendrites • Neuroglia—Support neurons, nourish, insulate, defend from infection Developmental Aspects • Three primary germ layers formed early in embryonic development and specialize to form the 4 tissues: o Ectoderm: nervous, epithelial (skin) o Mesoderm: muscle, connective, and epithelial o Endoderm: epithelial, organs of the viscera Organ • A structure comprised of 2 or more tissue types • Most organs are comprised of all 4 tissue types. Organ System • A group of organs performing the same function Levels of organization review • Atoms • Molecules • Organelles • Cells (75 trillion, 216 types) • Tissues (4) • Organs • Organ systems (11) • Organism (1) Metabolism • Process by which animals maintain life • Occurs at cellular level • Opposite chemical process of photosynthesis • Sugar and Oxygen convert to Carbon dioxide, Water, and Heat. Equation: C6H12O6 + O2 ----> CO2 + H2O + Heat Medical Terminology Root Words component ARTHRO BLAST BRACHIO BRONCH CARCIN CARDIO CEPHALO COLO CRANIO CYTO DERMA HEMO HEPA HIST HYSTER LEUK MAMMO MYO NEPHRO NEURO ONCO OSTEO PED PHLEB RENAL SARCO TOXO meaning joints germ, immature cell arms lungs, bronchial cancer heart head intestines skull cell skin blood liver tissue uterus white breast muscle kidney nerves mass / tumor bone / bony tissue child vein kidneys tissue poison example arthritis = inflammation of joints blastoma = a cancer made of immature cells brachial plexus bronchitis = swelling of the bronchial tubes carcinogenic = cancer causing cardiotoxicity = toxicity to the heart cephalic = relating to the head colostomy = incision into intestines craniotomy = cutting into the skull cytotoxic = toxic to the cell dermatitis = inflammation of the skin hemorrhage, hemoglobin, hemorrhoid hepatitis = liver inflammation histology = study of tissue hysterectomy = removal of uterus leukemia = white blood cell mammogram = breast image myopathy = disease of the muscle nephrotoxic = harmful to the kidneys neurob1ast = an immature nerve cell oncology = the study of cancer osteosarcoma = bone cancer pediatric oncology = study of childhood cancer phlebotomy = incision into a vein adrenal = next to the kidneys sarcoma = tumor of bone, muscle, or connective tissue toxicology = study of poisons Suffixes component -EMIA -ECTOMY -ITIS -OLOGY -OMA -OTOMY -PATHY -OSIS meaning condition of blood excision / removal inflammation study / science of tumor incision disease disease / condition example anemia = without hemoglobin nephrectomy = excision of a kidney hepatitis = inflammation of the liver cytology = the study of cells retinoblastoma = tumor of the eye craniotomy = incision into skull neuropathy = disease of the nervous system necrosis = dying cells Prefixes component AN-, AABADBIDYSECTOENDOEPIGLUCOGLYCHYPERHYPOINTERINTRAINFRAPARAPERIPREPOSTSCLEROSUBSUPRASYN- meaning without / lack of away from near / toward two / both difficult / not outside inside upon glucose sugar excessive / above beneath / below between within / inside beside, about, near around before after hardening / stiffening under / below above together with example anemia = lack of red blood cells abnormal = away from the normal adrenal gland = gland near to the kidney bilateral = both sides dysfunction = not working properly ectopic pregnancy = outside the uterine cavity endoscope = an instrument to look inside the body cavities or organs epidermis = the outer layer of skin glucocorticoid = hormone regulating glucose metabolism hyperglycemia = excessive blood sugar levels hyperglycemia = excessive blood sugar levels hypodermic = injection below the skin intercostal = between the ribs intravenous = into a vein infraspinatus = within the spines of the scapula parathyroid = beside the thyroid gland pericardium = membrane around the heart prenatal = before birth post surgical stage = stage after surgery scleroderma = hardening of the skin submucosa = tissue below mucus membrane supraspinatus = muscle above the spine (of scapula) syndrome = group of symptoms occurring together