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Cell Growth 10-1 GPS STANDARD • SB1. Students will analyze the nature of the relationships between structures and functions in living cells. • a. Explain the role of cell organelles for both prokaryotic and eukaryotic cells, including the cell membrane, in maintaining homeostasis and cell reproduction. I. Cell Growth • Unicellular Organisms- cell gets bigger • Multicellular Organisms- cell divides into more cells – The cells of an adult are the same size as the cells of the young. (Adults just have more cells) II. Limits to Cell Growth • 1. DNA Overload – As cells grow they don’t make more DNA so there would be an information crisis II. Limits to Cell Growth • 2. Ratio of Surface Area to Volume – Surface Area= l x w x # of sides – Volume= l x w x h II. Limits to Cell Growth – The rate of exchange of food entering and wastes leaving the cell depends on the surface area of the cell membrane. – The rate that food is used up and wastes are produced depends on the cell’s volume. – As the size of the cell increases, volume increases faster than surface area and causes problems for the cell- it can’t transport nutrients and wastes across fast enough for the cell to survive. III. Cell Division • Cells must divide before they get too big. • The process by which a cell divides into two new daughter cells is called Cell Division. IV. The Cell Cycle • Cell Cycle- the series of events cells go through as they grow and divide. IV. The Cell Cycle • A. Interphase: “the in-between phase” – G1 phase- cells grow – S phase- DNA replication and chromosome duplication (it copies the DNA) – G2 phase- prepares for mitosis by making needed organelles. IV. The Cell Cycle • B. M phase (mitosis & cytokinesis) – Mitosis- division of the nucleus • • • • 1. Prophase 2. Metaphase 3. Anaphase 4. Telophase – Cytokinesis- division of the cytoplasm – *the two newly formed daughter cells are identical* Cell Division 10-2 I. Chromosomes • made of DNA and proteins • Carry the genetic material • Every organism has a specific number of chromosomes. – Daughter cells have the same number of chromosomes as the parent cell – Human cells have 46 chromosomes • Usually chromosomes are not visible and it is called chromatin. During cell division the chromosomes are visible • During cell division the chromosomes are made up of two sister chromatids attached at a centromere. Chromosome Structure II. Stages of the cell cycle Interphase – The longest phase of the cell cycle – Includes G1, S, & G2 phases – It is a period of growth, DNA replication, and preparation for mitosis. – The nucleus is visible and surrounded by a nuclear membrane. • Mitosis- Division of the nucleus • 1. Prophase – – – – Nuclear membrane breaks down Nucleolus disappears Chromosomes coil up and become visible Centrioles separate and mitotic spindle starts to form PROPHASE • 2. Metaphase – Chromosomes attach to the spindle fibers at the centromeres – Chromosomes line up in the middle of the cell METAPHASE • 3. Anaphase – Sister chromatids begin to move toward opposite sides of the cell ANAPHASE • 4. Telophase – Two nuclear membranes start to reform – Chromosomes start to uncoil – Spindle breaks apart TELOPHASE • Cytokinesis- division of the cytoplasm – In Plant Cells- a cell plate forms between the two new daughter cells that will eventually turn into a new cell wall to separate them. – In Animal Cells- a furrow forms between the two new cells and pinches the cell membrane until two new cells form. CYTOKINESIS-Splitting of the cytoplasm. Animal Cell Reproduction (Mitosis) Plant Cell Reproduction (Mitosis)