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The way to my heart is through the blood vessels….. Heart • Hollow, muscular, organ that pumps blood throughout the body • Each time the heart beats, it pushes blood through the blood vessels • About the size of your fist • Behind the sternum • Inside the rib cage • Cardiac muscle (can contract over and over without getting tired) Structure • Septum – Wall of tissue – Separates left side from right side of heart • Atrium – Upper chambers of heart – Receive blood coming into the heart • Ventricle – Lower chambers of heart – Pumps blood out of the heart Structure • Pacemaker – Group of heart cells in right atrium – Sends out signals that make the heart muscle contract • Valves – Flap of tissue that prevents blood from flowing backward – Located between the atria and the ventricles • Tricuspid valve (right side) • Mitral valve (left side) – Located between the ventricles and blood vessels • Pulmonic valve • Aortic valve Valve Blood Vessels • Superior Vena Cava – Blood from upper body flows through Superior Vena Cava into right atrium • Inferior Vena Cava – Blood from lower body flows through Inferior Vena Cava into right atrium Blood Vessels • Pulmonary Artery – Blood flows out of right ventricle into pulmonary artery – Flows to both the right and left lungs • Pulmonary Vein – Blood flows from lungs into the left atrium • Aorta – Blood flows out of left ventricle to the body Loops • Loop One Blood goes from the heart to the lungs then back to the heart. • Loop Two Blood is pumped from the heart through out the body and then returns to the heart. Blood • Four Components: – Plasma – liquid part of blood (water makes up 90%) • Protein molecules make it yellow • Three groups of plasma proteins: 1st – regulates amount of water in blood, 2nd – helps fight disease, 3rd – interacts with platelets to form clots – Red Blood Cells – delivers oxygen from the lungs to the cells in the body • Produced in the bone marrow • Made mostly of hemoglobin (iron-containing protein which binds chemically to oxygen molecules) • Mature red blood cells live about 120 days • Every second, about 2 million die Blood cont… – White Blood Cells – the body’s disease fighters • Produced in bone marrow • Some alert the body to invading bacteria, some produce chemicals to fight the bacteria, and some surround the invaders to kill them. • There are fewer white bc than red bc (only about one white bc for every 500 to 1000 red bc) • White blood cells contain nuclei and can live for months or even years. Blood cont…. – Platelets – cell fragments that help with the clotting of blood • When a vessel is cut, platelets collect and stick to the vessel at the site of the wound and release chemicals that start a chain reaction which produces the protein fibrin. • Fibrin – a net of fibers that form across the cut in a blood vessel. Cardiovascular Health • Cardiovascular disease is the leading cause of death in the U.S. • Atherosclerosis – Condition in which an artery wall thickens as a result of the buildup of fatty materials • Ex. Cholesterol: a waxy substance – Results in reduced flow of blood in the affected artery Heart Attack • Atherosclerosis develops in coronary arteries – Coronary arteries supply heart with oxygen – Block in coronary arteries • less blood to heart → less oxygen to heart • Heart attack occurs when blood flow to part of the heart muscle is blocked • Cells die when they do not receive blood and oxygen • Causes permanent damage to heart Treatment for Atherosclerosis • Low-fat diet • Moderate exercise program • Medications to lower cholesterol and fats in blood • Severe atherosclerosis may need surgery to unclog arteries Hypertension • High blood pressure • Disorder in which a person’s blood pressure is consistently higher than normal • Cause heart to work harder to pump blood • Can damage walls of blood vessels • “silent killer” – No obvious symptoms until damage is severe Treatment for Hypertension • Related to atherosclerosis – As blood vessels narrow, blood pressure raises • Diet and exercise • Limit intake of sodium • medication History of Cardiovascular Medicine • • • • • • 1930s-40s: Blood banks 1958: External artificial pacemaker 1961: Heart valve replacement 1967: First heart transplant 1977: Angioplasty 2001: Replacement heart Stay Healthy! • Exercise regularly • Eat balanced diet that is low in… • Saturated fats – High: Butter, whole milk, and ice cream • Trans fats – High: Margarine, potato chips, and doughnuts • Cholesterol – High: red meat, eggs, cheese • Sodium – High: salt, processed foods • Don’t smoke – Smokers are more than twice as likely to have a heart attack Cardiovascular System Review Blood • Four components of blood – Red Blood Cell – White Blood Cell – Platelets – Plasma