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2013-2015 Cuyahoga County Sexually Transmitted Diseases Report: Chlamydia and Gonorrhea— Executive Summary Chlamydia cases and rates for Cuyahoga County (left) and Cleveland (right). Cases are denoted as lines, while rates per 100,000 in population are denoted as vertical bars. Trends have shown a decrease in the rates and number of cases in recent years, with a 12% decrease in rates from 2015* compared to rates from 2012 for the county, and an 18% decrease in rates from 2015* compared to rates from 2012 for Cleveland. Gonorrhea cases and rates for Cuyahoga County (left) and Cleveland (right). Cases are denoted as lines, while rates per 100,000 in population are denoted as vertical bars. Trends have also shown a decrease in the rates and number of cases in recent years, with an 18% decrease in rates from 2015* compared to rates from 2012 for the county, and a 20% decrease in rates from 2015* compared to rates from 2012 for Cleveland. 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 1 2013-2015 City of Cleveland and Cuyahoga County Sexually Transmitted Diseases Report: Chlamydia and Gonorrhea— Executive Summary continued... Co-infection of Chlamydia and Gonorrhea cases and rates for Cuyahoga County (left) and Cleveland (right). Cases are denoted as lines, while rates per 100,000 in population are denoted as vertical bars. Trends have shown a decrease in the rates and number of cases in recent years, with a 26% decrease in rates from 2015* compared to rates from 2012 for the county, and a 29% decrease in rates from 2015* compared to rates from 2013 for Cleveland. Cases and rates were not available before 2012 for the county and before 2013 for Cleveland. *2015 data is preliminary. 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 2 Cleveland Department of Public Health Office of Communicable Disease Surveillance and Epidemiology 2013 2013--2015 Cuyahoga County Sexually Transmitted Diseases Report: Chlamydia and Gonorrhea Cleveland Department of Public Health 75 Erieview Plaza Cleveland, OH 44114 Phone: 216-664-3747 Fax: 216-664-6159 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 3 2013-2015 Cuyahoga County Sexually Transmitted Diseases Report: Chlamydia and Gonorrhea Cleveland Department of Public Health Office of Communicable Disease Surveillance and Epidemiology The Cleveland Department of Public Health would like to thank the following for their contributions to this report: Cleveland Department of Public Health Alisha Cassady, MPH Candidate Vinothini Sundaram, MPH Office of Communicable Disease Surveillance and Epidemiology Jackie Tomer, MPH Office of Communicable Disease Surveillance and Epidemiology Data prepared by Ohio Department of Public Health ODRS (Ohio Disease Reporting System). Surveillance performed in cooperation with the Cuyahoga County Board of Health. 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 4 Table of Contents Sexually Transmitted Diseases Introduction…………………………………………………………………….……………………………………pg. 7 Chlamydia…………………………………………………………………………………………………………………………………….……………………….pg. 8 Chlamydia Introduction………………………………………………………………………………………………………………...………….pg. 9 Chlamydia Statistics……………………………………………………………………………………………………..………………………...pg. 10 Chlamydia by Municipality……………………………………………………………………….……………………………………………..pg. 11 Chlamydia by Sex………………………………………………………………………………………………….………………………………...pg. 12 Chlamydia by Age…………………………………………………………………………………………………………….…………..………...pg. 13 Chlamydia by Age and Sex…………………………………………………………………………………………………………….…………pg. 14 Chlamydia by Race……………………………………………………………………………………………….………………………………….pg. 15 Chlamydia by Ethnicity………………………………………………………………………………………………………………..………….pg. 16 Gonorrhea………………………………………………………………………………………….………………………………………………….…………..pg. 17 Gonorrhea Introduction……………………………………………………………………………………………………………………….….pg. 18 Gonorrhea Statistics………………………………………………………………………..………………………………………….…………..pg. 19 Gonorrhea by Municipality………………………………………………………………………………..………………………….………..pg. 20 Gonorrhea by Sex………………………………………………………………………………………………………….………………………..pg. 21 Gonorrhea by Age……………………………………………………………………………………………………………………..…………….pg. 22 Gonorrhea by Age and Sex………………………………………………………………………..…………………………………………....pg. 23 Gonorrhea by Race…………………………………………………………………………………………………………………….…………...pg. 24 Gonorrhea by Ethnicity……………………………………………………………………………………………..…………………………....pg. 25 Co-Infections of Chlamydia and Gonorrhea………………………………………………………………………………………………….……..pg. 26 Co-Infections Introduction………………………………………………………………………………………………………………………pg. 27 Co-Infections by Municipality………………………………………………..…………………………….………………………………….pg. 28 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 5 Co-Infections by Sex………………………………………………………………………………………………………..………………………pg. 29 Co-Infections by Age………………………………………………………………………………………………………………………………..pg. 30 Co-Infections by Age and Sex…………………………………………………………………………………………………………………..pg. 31 Co-Infections by Race………………………………………………………………………………………………………………………………pg. 32 Co-Infections by Ethnicity………………………………………………………………………………………………………………………..pg. 33 Populations of Special Interest………………………………………………………………………………………………………..………………….pg. 34 Recommendations………………………………………………………………………………………………………………………………………………pg. 37 Future Directions…………………………………………………………………………………………………………………………………………………pg. 38 Testing Centers……………………………………………………………………..…………………………………………………………………………….pg. 39 Appendix…………………………………………………………………………………………….………………………………………………………………pg. 41 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 6 Sexually Transmitted Diseases Introduction Sexually transmitted diseases (STDs) are infections that are spread through sexual contact. Sexually transmitted infection (STI) is a broader term for STD; some STDs do not cause symptoms, but are still considered to be an infection. An infection is considered to be a disease when it causes altered function in the body (University of Maryland, University Health Center, 2009). STDs can be caused by bacteria, parasites, or viruses. STDs can be transmitted through blood, semen, vaginal fluids, and other body fluids. There are over 20 types of STDs. STDs affect both men and women, however, some can cause more severe complications in women. Treatment for STDs varies depending on the type of infection. Using latex condoms can greatly reduce the risk of contracting an STD. A pregnant woman who is infected with an STD is at risk for transmitting the infection to her unborn baby. Often, STDs present as asymptomatic until long-term complications occur. Chlamydia and gonorrhea are among the most common STDs in the United States. 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 7 Chlamydia 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 8 Chlamydia Introduction What is Chlamydia? How is Chlamydia transmitted? Chlamydia is caused by the bacteria Chlamydia trachomatis. Chlamydia is spread through vaginal, anal, or oral sex with an individual who is infected. It is the most commonly reported sexually transmitted disease (STD) in the United States. It has comprised the largest portion of reported STIs to the CDC since 1994. In 2014, there were a total of 1,441,789 chlamydia cases reported to the CDC. Infection can occur days to months after the initial exposure. Chlamydial infection can facilitate the transmission of Human Immunodeficiency Virus (HIV). Chlamydia can also be passed from mother to child during childbirth (congenital infection). It can also increase the likelihood that a woman will deliver her baby early. Diagnosis and Treatment of Chlamydia Often, chlamydia presents with no symptoms. In some cases, symptoms may not appear for several weeks after infection has occurred. In women, chlamydia can cause abnormal vaginal discharge and a burning sensation when urinating. In men, chlamydia can cause discharge from the penis, a burning sensation when urinating, and pain or swelling in one or both testicles. However, men rarely experience health complications associated with chlamydia. Chlamydia is often diagnosed through cultures from swabs of either the cervix in women or the urethra in men. Chlamydia can also be diagnosed from a urine sample. Chlamydia is easily cured with antibiotics. However, if left untreated, it can cause a condition called Pelvic Inflammatory Disease (PID), which can make it difficult for women to get pregnant. Individuals being treated for chlamydia should abstain from sexual activity for seven days during treatment. Repeat infection with chlamydia is common. Pap smear showing Chlamydia trachomatis Prevention of Chlamydia Infection Annual screening for chlamydia is recommended for all sexually active women who are less than 25 years old or who have multiple risk factors (e.g., multiple new sexual partners). Chlamydia screening for men is recommended in areas with a high burden of the disease. Using latex condoms correctly can greatly reduce the likelihood of contracting chlamydia. 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 9 Chlamydia Statistics www.cdc.gov Chlamydia has the highest prevalence in individuals under 24 years old. In 2014, Ohio was #18 in the United States for chlamydia infections (with 54,858 cases and a rate of 474.1 per 100,000). Cuyahoga County was #20 in the United States for chlamydia infections in 2014 (with 9,072 cases and a rate of 718.2 per 100,000). Trends overtime have shown that chlamydia is more common in women than in men. Adolescents and young adults tend to have the highest rates of chlamydia (among 15-24 year olds). Trends in chlamydia infections also show that the infection is most common in Non-Hispanic African Americans. From 2013-2015, there were 28,121 chlamydia infections in Cuyahoga County. www.cdc.gov 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 10 Chlamydia Cases by Municipality, 2013 2013--2015 Figure 2. Graph of Chlamydia cases in Cuyahoga County municipalities in 2013-2015 (above). The top five municipalities with the most infections are indicated on the graph. Some municipalities had no Chlamydia infections in 2013-2015. As shown, Cleveland comprises over 50% of the Chlamydia infections in 2013-2015. Rates of infection are provided in Table 1 of the Appendix. Figure 3. Chlamydia cases in Cleveland compared to other major metropolitan areas in Ohio (right). Numbers obtained from the Ohio Department of Health (ODH). As shown, Cleveland had a significantly larger number of chlamydia infections than most other major metropolitan areas in Ohio. Statistics for 2015 were not yet available. 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 11 Chlamydia Cases by Sex, 2013 2013--2015 Sex Number of Cases Female 19,518 Male 8,602 Total 28,120* The table to the left shows the number of Chlamydia infections in Cuyahoga County for 2013-2015 by sex. There was one individual with no sex data. The number of females with Chlamydia infections is two times the number of infections in males. Rates of infection are provided in Table 2 of the Appendix. *: Sex unknown for one individual Figure 4. Graph of Chlamydia cases in Cuyahoga County for 2013-2015 by sex. As also shown in the graph above, females comprise over 50% of the Chlamydia infections in Cuyahoga County for 2013-2015. 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 12 Chlamydia Cases by Age, 2013 2013--2015 The table to the right shows the number of Chlamydia infections in Cuyahoga County for 2013-2015 by age. 20-24 year olds and 15-19 year olds have the highest and second highest number of infections, respectively. 20-24 year olds and 15-19 year olds have over two times the number of infections when compared to 25-29 year olds. Rates of infections are provided in Table 3 of the Appendix. Age Number of Cases 0-9 years old 19 10-14 years old 430 15-19 years old 9,712 20-24 years old 10,783 25-29 years old 4,080 30-34 years old 1,657 35-39 years old 716 40-44 years old 348 45-54 years old 268 55-64 years old 86 65+ years old 13 Total 28,121 Figure 5. Graph of Chlamydia infections in Cuyahoga County for 2013-2015 by age (left). Percentages are labeled for the three age groups with the highest number of infections. Adolescents and young adults (20-24 year olds and 15-19 year olds) comprise almost 75% of the total number of infections. 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 13 Chlamydia Cases by Age & Sex, 2013 2013--2015 Age Female Cases Male Cases 0-9 years old 10 9 10-14 years old 378 52 15-19 years old 7,221 2,491 20-24 years old 7,682 3,100 25-29 years old 2,582 1,498 30-34 years old 941 716 35-39 years old 371 345 40-44 years old 174 174 45-54 years old 117 151 55-64 years old 35 51 65+ years old ** 10 Total* 19,514 8,597 The table to the left shows the number of Chlamydia infections in Cuyahoga County for 2013-2015 by age and sex. In both sexes, 20-24 year olds and 15-19 year olds have the highest and second highest number of chlamydia infections, respectively. Until ages 40-44, females have higher numbers of infections. After 45, an increase in the number of infections is noticed in males; they have higher numbers of infections. Rates of infection are provided in Tables 4 and 5 of the Appendix. *: Sex was unknown for one individual **: Rate data are suppressed when case counts are 5 or less Figure 6. Graph of Chlamydia infections in Cuyahoga County for 2013-2015 by age and sex. As shown in the graph above, females have two to seven times the amount of infections as males up to ages 40-44. However, after ages 45-54, an increase in the number of infections can be seen in males, and their numbers surpass those of females. 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 14 Chlamydia Cases by Race, 2013 2013--2015 Race Number of Cases American Indian/Alaskan Native 27 Asian 97 African American 17,687 Hawaiian Native/Pacific Islander 7 Multiracial ** Some Other Race 914 Caucasians 4,254 Total* 22,987 The table to the left shows the number of Chlamydia infections for Cuyahoga County for 2013-2015 by race. African Americans have more than four times the number of Chlamydia infections as Caucasians. African Americans are also the minority population who are most adversely affected with Chlamydia infections. Rates of infection are provided in Table 6 of the Appendix. *: 5,134 individuals missing, had unknown, or refused to answer race data **: Rate data are suppressed when case counts are 5 or less Figure 7. Graph of Chlamydia infections for Cuyahoga County in 2013-2015 by race. As shown in the graph to the left, African Americans comprise more than 75% of those individuals with Chlamydia infections, while Caucasians comprise less than 20%. Other minority populations contribute very little to the total number of infections. 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 15 Chlamydia Cases by Ethnicity, 2013 2013--2015 Ethnicity Number of Cases Hispanic or Latino 460 Non-Hispanic or Non-Latino 17,164 Total* 17,624 The table to the left shows Chlamydia infections for Cuyahoga County in 2013-2015 by Ethnicity. Non-Hispanics/Non-Latinos have over 35 times the number of Chlamydia infections as Hispanics or Latinos. There was a large number of individuals with missing ethnicity data. Rates of infection are provided in Table 7 of the Appendix. *: 10,497 individuals missing, had unknown, or refused to answer ethnicity data Figure 8. Graph of Chlamydia infections for Cuyahoga County in 2013-2015 by ethnicity. As shown in the graph to the right, Non-Hispanics/Non-Latinos comprise almost all of the cases of Chlamydia in Cuyahoga County during this period. 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 16 Gonorrhea 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 17 Gonorrhea Introduction What is Gonorrhea? Gonorrhea, or gonococcal infection, is caused by the bacterium Neisseria gonorrhaeae. It is the second most commonly reported communicable disease. The Centers for Disease Control and Prevention (CDC) estimate there are 820,000 new gonococcal infections annually, but only half of these infections are reported Image of the gonorrhea bacterium to the CDC. How is Gonorrhea transmitted? Gonorrhea is transmitted through sexual contact with the penis, vagina, mouth, or anus of an infected partner. Infection can also spread from mother to child during childbirth (perinatally). An infant who is infected with Gonorrhea could experience blindness, joint infection, or blood infection. Gonorrhea infects the mucous membranes of the cervix, uterus, and fallopian tubes in women, and the urethra in men and women. It also can infect the mucous membranes of the mouth, eyes, throat, and rectum. www.cdc.gov Diagnosis and Treatment of Gonorrhea Men and women are often asymptomatic. Symptoms usually include dysuria (painful or difficult urination), discharge from the urethra in men or vagina in women, or bleeding between periods in women; these symptoms may appear up to five days after exposure. Women with gonorrhea are at a high risk of developing complications, such as PID. If left untreated, gonococcal infection can increase the risk for HIV and arthritis. Some strains of N. gonorrhaeae have developed resistance to the drugs used to treat them. This has created a problem because now very few antibiotics can be used to treat it. Some risk factors for gonococcal infection include inconsistent condom use, previous or coexisting STDs, and exchanging sex for money or drugs. Prevention of Gonococcal Infection Gonococcal infection is treated with a dual antibiotic therapy. Re-infection can occur, even after treatment. Gonorrhea is normally diagnosed through urine testing. The CDC recommends yearly screening for sexually active women younger than 25 years old, or older women who have many risk factors. Using latex condoms correctly can greatly reduce the likelihood of contracting gonorrhea. Sexual contact should be avoided until treatment is complete. 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 18 Gonorrhea Statistics In 2014, there were 350,062 cases of gonorrhea reported to the CDC. In the United States, the highest rates of infection are among teens, young adults, and African Americans. Gonorrhea tends to concentrate in specific geographic locations and within communities. Certain subgroups of men who have sex with men (MSM) are at a high risk for gonococcal infection. In 2014, Ohio was #9 in the United States for gonorrhea, with 16,237 infections and a rate of 140.3 per 100,000. Cuyahoga County was #13 in the United States for gonococcal infections in 2014 (with 3,213 infections and a rate of 254.4 per 100,000). Similar to chlamydia, gonorrhea tends to have higher rates in individuals aged 15-24 years old. It also tends to be higher in Non-Hispanic African Americans. From 2013-2015, there were 9,904 gonococcal infections in Cuyahoga County. www.cdc.gov 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 19 Gonorrhea Cases by Municipality, 2013 2013--2015 Figure 10. Graph of gonococcal infections in Cuyahoga County municipalities in 2013-2015 (left). The top five municipalities with the most infections are indicated on the graph to the left. Some municipalities had no gonococcal infections in 2013-2015. As shown, Cleveland comprises over 60% of the gonococcal infections in 2013-2015. Figure 11. Gonorrhea cases in Cleveland compared to other major metropolitan areas in Ohio (right). Numbers obtained from ODH. As shown, Cleveland had a significantly higher number of gonococcal infections than most other major metropolitan areas in Ohio. Statistics for 2015 were not yet available. 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 20 Gonorrhea Cases by Sex, 2013 2013--2015 Sex Number of Cases Female 5,319 Male 4,585 Total 9,904 The table to the left gives the total number of gonococcal infections in Cuyahoga County for 2013-2015. Sex data was available for all individuals infected. Females out-number males in the number of infection. However, their rates of infection between males and females are similar. Rates of infection are supplied in Table 9 in the Appendix. Figure 12. Graph of gonococcal infections in Cuyahoga County for 20132015 by sex (right). As also illustrated in the table above, women out-number men in regards to numbers of gonococcal infections. However, their rates of infection are relatively similar. 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 21 Gonorrhea Cases by Age, 2013 2013--2015 The table to the right shows the number of gonococcal infections in Cuyahoga County for 2013-2015 by age. 20-24 year olds had the largest number of infections, followed by 15-19 year olds. 15-19 year olds had almost two times the number of gonococcal infections compared to 25-29 year olds. Rates of infection are supplied in Table 10 in the Appendix. Age Number of Cases 0-9 years old ** 10-14 years old 168 15-19 years old 2,991 20-24 years old 3,442 25-29 years old 1,576 30-34 years old 774 35-39 years old 377 40-44 years old 209 45-54 years old 246 55-64 years old 94 65+ years old 20 Total* 9,902 *: 2 individuals missing age data **: Rate data are suppressed when case counts are 5 or less Figure 13. Graph of gonococcal infections in Cuyahoga County for 20132015 by age (left). As also illustrated in the table above, 20-24 year olds and 1519 year olds comprise most of the gonococcal cases for 2013-2015. Combined, they comprise 65% of the cases. 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 22 Gonorrhea Cases by Age & Sex, 2013 2013--2015 Age Female Cases Male Cases 0-9 years old ** ** 10-14 years old 134 34 15-19 years old 1,928 1,063 20-24 years old 1,964 1,478 25-29 years old 720 856 30-34 years old 303 471 35-39 years old 127 250 40-44 years old 64 145 45-54 years old 52 194 55-64 years old 19 75 65+ years old ** 18 Total* 5,317 4,585 The table to the left shows the number of gonococcal infections in Cuyahoga County for 2013-2015 by age and sex. In both sexes, 20-24 year olds and 15-19 year olds have the highest and second highest number of gonococcal infections, respectively. After 24 years old, the number of infections greatly increases in males, with the male sex comprising most of the number of infections after the age of 24. Rates for infections are supplied in Tables 11 and 12 in the Appendix. *: 2 individuals missing age data **: Rate data are suppressed when case counts are 5 or less Figure 14. Graph of gonococcal infections in Cuyahoga County for 2013-2015 by age and sex. As shown in the graph to the right, females who are 20-24 and 15-19 years old have the highest number of gonococcal infections. However, after 24 years old, there is an upward trend in the number of infections in males, and their number surpasses that of females. 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 23 Gonorrhea Cases by Race, 2013 2013--2015 Race Number of American Indian/Alaskan Native 13 Asian 22 African American 7,325 Hawaiian Native/Pacific Islander ** Other 243 Caucasian 907 Total* 8,511 The table to the left shows the number of gonococcal infections in Cuyahoga County for 2013-2015 by race. Similar to Chlamydia, African Americans had the highest number of infections. African Americans had eight times the number of gonococcal infections as Caucasians. Rates of infection are provided in Table 13 of the Appendix. *: 1,393 individuals missing, had unknown, or refused to answer race data **: Rate data are suppressed when case counts are 5 or less Figure 15. Graph of gonococcal infections in Cuyahoga County for 2013-2015 by race. As shown in the graph to the right, African Americans comprise more than 75% of the number of gonococcal infections in Cuyahoga County for this period, while Caucasians only comprise only about 10%. Again, other minority populations contribute very little to the total number of infections. 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 24 Gonorrhea Cases by Ethnicity, 2013 2013--2015 Ethnicity Number of Cases Hispanic or Latino 157 Non-Hispanic or Non-Latino 6,500 Total* 6,657 The table to the left shows the number of gonococcal infections for Cuyahoga County in 2013-2015 by ethnicity. Similar to Chlamydia, Non-Hispanic/Non-Latinos had 41 times the number of infections as Hispanic/Latinos. There were also a large number of individuals with missing ethnicity data. Rates of infection are provided in Table 14 of the Appendix. *: 3,247 individuals missing, had unknown, or refused to answer ethnicity data Figure 16. Graph of gonococcal infections for Cuyahoga County in 2013-2015 by ethnicity (right). As also shown in Chlamydia cases in 2013-2015, Non-Hispanic/Non-Latinos comprise almost all of this population with gonococcal infections in Cuyahoga County during this period. 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 25 Co Co--Infections of Chlamydia & Gonorrhea 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 26 Co Co--Infections Introduction What is co-infection? Co-infection is contracting a second STD while already infected with a different STD. Being infected with one STD increased the likelihood of being infected with a second STD. Chlamydia and gonorrhea are the two most commonly reported bacterial STDs, which increases the likelihood of co-infection. If caught early, only a single dose of antibiotics is required to treat both infections. Transmission electron micrograph of Chlamydia trachomatis Similarities between Chlamydia and Gonorrhea Chlamydia and Gonorrhea have similar symptoms of infection. These two organisms also infect similar mucosal membranes. Because of these similarities, an individual can easily become infected with both infections. This also suggests that individuals should be tested for both STDs simultaneously, especially if they exhibit risk factors. Chlamydia and Gonorrhea Co-Infection Statistics Data from the Virginia Department of Health suggests that 40-50% of 15-24 year olds who have tested positive for Gonorrhea are co-infected with Chlamydia. This same data also suggested that women and African Americans are more likely to have a co-infection. Women are also more likely to develop complications from co-infections, such as PID. In 2013-2015, there were 3,325 co-infections of Chlamydia and Gonorrhea in Cuyahoga County. Scanning electron micrograph of Neisseria gonorrhoeae 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 27 Co Co--Infections Cases by Municipality, 2013 2013--2015 Figure 18. Graph of Co-Infection Cases in Cuyahoga County Municipalities in 2013-2015 (left). The top five municipalities with the most co-infections are indicated on the graph. Some municipalities had no co-infections infections in 2013-2015. As shown, Cleveland comprises over 60% of the co-infections in 2013-2015. Figure 19. Graph of co-infection cases for Cleveland, Ohio in 20122015. As shown, the number of co-infections of Chlamydia and Gonorrhea has steadily decreased since 2013. Unfortunately, data was not available to compare to other cities in Ohio. 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 28 Co Co--Infection Cases by Sex, 2013 2013--2015 The table to the right shows the number of co-infection cases in Cuyahoga County for 2013-2015 by sex. Sex data was available for all individuals. The number of females with co-infections out-numbers that of males by more than 50%. Rates for infection are supplied in Table 16 in the Appendix. Sex Number of Cases Female 1,981 Male 1,344 Total 3,325 Figure 20. Graph of the number of co-infection cases in Cuyahoga County for 2013-2015 by sex (left). As also shown in the table above, females out-number males in regards to number of co-infection cases. Because of this, women also have a higher rate of co-infection cases. 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 29 Co Co--Infection Cases by Age, 2013 2013--2015 Age Number of Cases 0-9 years old ** 10-14 years old 88 15-19 years old 1,394 20-24 years old 1,180 25-29 years old 379 30-34 years old 139 35-39 years old 65 40-44 years old 32 45-54 years old 32 55-64 years old 14 65+ years old ** Total 3,325 The table to the left shows the number of co-infection cases in Cuyahoga County for 2013-2015 by age. 15-19 year olds have the highest number of co-infections, followed closely behind by 20-24 year olds. 15-19 year olds had almost four times the number of co-infections cases compared 25-29 year olds. Rates of infection are supplied in Table 17 in the Appendix. **: Rate data are suppressed when case counts are 5 or less Figure 21. Graph of co-Infection cases in Cuyahoga County for 2013-2015 by Age (right). As also illustrated in the table above, 15-19 year olds and 20-24 year olds comprise most of the co-infection cases for 2013-2015. Combined, they comprise over 75% of the cases. 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 30 Co Co--Infection Cases by Age & Sex, 2013 2013--2015 The table to the right shows the number of co-infection cases in Cuyahoga County for 2013-2015 by age and sex. In females, 15-19 year olds had the highest number of infections, while in males, 20-24 year olds had the highest number of infections. 15-19 year old females also have two times the number of co-infection cases when compared to 15-19 year old males. After 24 years old, the number of infections increases rapidly in males, with the male sex comprising most of the number of infections after this age. Numbers and rates of infection are supplied in Tables 18 and 19 in the Appendix. Age 0-9 years old 10-14 years old 15-19 years old 20-24 years old 25-29 years old 30-34 years old 35-39 years old 40-44 years old 45-54 years old 55-64 years old 65+ years old Total Female Cases ** 73 943 691 178 59 19 7 7 ** ** 1,981 Male Cases ** 15 451 489 201 80 46 25 25 11 ** 1,344 **: Rate data are suppressed when case counts are 5 or less Figure 22. Graph of co-infection cases in Cuyahoga County for 2013-2015 by age and sex. As shown also shown in the table above, women have a significantly higher number of infections until 25 years old; at this point, males have a much higher number of infections. 15-24 year old females and males also comprise the largest number of co-infection cases. 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 31 Co Co--Infection Cases by Race, 2013 2013--2015 Race Number of Cases American Indian/Alaskan Native ** Asian 8 African American 2,508 Other 69 Caucasian 264 Total* 2,854 The table to the left shows the number of co-infection cases by race. African Americans have the largest number of infections. The number of co-infection cases in African Americans is almost ten times the number of co-infection cases in Caucasians. There were very few co-infection cases in minority populations (excluding African Americans); the number of co-infections in minorities only comprises about 3% of the total number of co-infections. Numbers and rates of infection are provided in Table 20 in the Appendix. *: 471 individuals missing or had unknown race data **: Rate data are suppressed when case counts are 5 or less Figure 23. Graph of co-infection cases in Cuyahoga County for 2013-2015 by race (right). As also shown in the table above, African Americans comprise most of the coinfection cases in Cuyahoga County during this time period, making up 88% of the total number of co-infection cases. As also stated above, minority populations other than African Americans contribute very little to the total number of cases. 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 32 Co Co--Infection Cases by Ethnicity, 2013 2013--2015 The table to the right shows the number of co-infection cases in Cuyahoga County for 2013-2015 by ethnicity. Similar to both chlamydia and gonorrhea, Non-Hispanic/Non-Latinos comprise the vast majority of the population with co-infections. However, about one-third of individuals are missing or have unknown ethnicity data. Numbers and rates of infection are provided in Table 21 of the Appendix. Ethnicity Number of Cases Hispanic or Latino 43 Non-Hispanic or Non-Latino 2,191 Total* 2,234 *: 1,091 individuals missing or had unknown ethnicity data Figure 24. Graph of co-infection cases in Cuyahoga County for 2013-2015 by ethnicity. As also shown in the table above, Non-Hispanic/Non-Latinos comprise the vast majority of the population with co-infection cases. Hispanic/Latinos only make up 2% of the total number of individuals with a co-infection. 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 33 Populations of Special Interest Women Women are at a higher risk for all types of STDs. Explanations for this occurrence include her relationship status with a male partner and social factors, such as access to healthcare for sexual health and socioeconomic status (SES), and inability to negotiate safe sex practices (e.g., condom use). Women with Chlamydia and Gonorrhea in particular are at an increased risk of developing PID, which can cause serious www.cdc.gov consequences to reproductive health. Often, both chlamydia and gonorrhea are asymptomatic in women, and are often only detected through screening. It is estimated that 1020% of women will develop PID if they do not receive adequate treatment for chlamydia or gonorrhea (CDC, 2014). Chlamydia and Gonorrhea can also result in adverse outcomes in pregnancy, including neonatal ophthalmia and neonatal pneumonia (CDC, 2014). Rates of both Chlamydia and Gonorrhea have been steadily increasing in women in the United States since 1993 (CDC, 2014). This increase could be due in part to increased screening efforts all over the United States. However, locally rates have decreased in recent years. In Cuyahoga County, Chlamydia rates in women in 2013 were 1,052.23 www.cdc.gov per 100,000, however, rates decreased in 2015 to 929.31 per 100,000. These rates are still much higher compared to men (in males rates in 2013 and 2015 were 489.49 per 100,000 and 466.61 per 100,000, respectively). These rates are similar for gonorrhea and co-infections, with women having a higher rate than men. However, the difference between females and males is not as great when comparing gonorrhea and co-infections. In 2015, the rate of gonorrhea in women was 229.5 per 100,000; in men, the rate of Gonorrhea in 2015 was 244.83 per 100,000. This shows the rate of Gonorrhea is actually increasing in men, which also coincides with national data. For co-infections, the rate in women in 2015 was 76.85 per 100,000; the same rate in males was 68.49. (All rates of infection are available in the tables in the Appendix.) Adolescents and Young Adults In recent years, national STD incidence has increased in adolescents and young adults aged 15-24 years old. It is estimated that this age group acquires half of all new STD cases and that 1 in 4 sexually active adolescent females have an STD (CDC, 2014). This age group is often at an increased risk of acquiring an STD because of differences in behavior, www.cdc.gov biology (i.e., immature reproductive system), or culture. This increased incidence could also be due to many barriers to accessing healthcare, such as inability to pay for services, lack of transportation, schedule conflicts, and stigma surrounding STD treatment. In 2015, adolescents and young adults aged 15-24 years old comprised over 60% of all Chlamydia, Gonorrhea, and (cont’d on next page) 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 34 Adolescents and Young Adults cont’d... co-infections cases in Cuyahoga County. However, trends in rates show that incidence of both STDs is in both of these age groups. For example, in 2013, the rate of Chlamydia in 15-19 year olds was 4,049.71 per 100,000, but in 2015 this rate decreased to 3,362.92 per 100,000. However, these rates are still high when compared to other groups. In 2015, rates of co-infection in 15-19 year olds was 408.3 per 100,000, while the same rate in 25-29 year olds was only 161 per 100,000; this means the rate of co-infection is two-and-a-half times higher in 15-19 year olds. A similar trend has been identified in Chlamydia and Gonorrhea cases. In 2015, rates of Chlamydia in 15-19 year olds was 3,362.92 per 100,000 compared to 1,792.99 per 100,000 in 25-29 year olds; this means the rate is almost two times higher in 15-19 year olds. Similarly, in Gonorrhea cases in 15-19 year olds, the rate in 2015 was 906.47 per 100,000, compared to 25-29 year olds www.cdc.gov whose rate was 667.19 per 100,000; the rate in 15-19 year olds is almost 50% higher than the rate in 25-29 year olds. (All rates of infection are available in the tables in the Appendix.) Racial and Ethnic Minorities Recent surveillance has shown higher rates of STDs in some racial and ethnic minority groups when compared to Caucasians. These higher rates are sometimes attributed to higher rates of poverty, low SES, differences in education, and poor access to healthcare. Often, there is also fear and distrust of healthcare workers among minority groups, which also prevents these individuals from accessing care. Even when care is accessible, the quality of care may differ for these minority patients. All www.cdc.gov of these aspects are observed when examining the incidence of STDs among different races and ethnicities. Rates of infection for Chlamydia, Gonorrhea, and co-infection are generally higher in all minority populations when compared to Caucasians (excluding Asians). In Cuyahoga County, however, African Americans were the only well represented minority population in Chlamydia, Gonorrhea, and co-infection cases. For all types of infections, African Americans comprised over 60% of the total number of infections. In 2015, the rate of Chlamydia in African Americans in Cuyahoga County was 1,414.49 per 100,000, while the same rate in Caucasians was 171.85 per 100,000; this shows that African Americans had eight times the number of Chlamydia infections compared to Caucasians. The same trend was observed in Gonorrhea and co-infection cases. For Gonorrhea cases in Cuyahoga County in 2015, African Americans had a rate of 559.71 per 100,000, while Caucasians only had a rate of 35.25 per 100,000; this means that African Americans had a rate almost sixteen times higher than Caucasians. For co-infection cases in Cuyahoga County for 2015, African Americans had a rate of 175.96 per 100,000, while the rate in Caucasians was 7.49 per 100,000; this means that the rate was almost twenty-four times higher in African Americans than Caucasians. While rates are higher in other minority populations in Cuyahoga County, there are very few cases in other minority populations of Chlamydia, Gonorrhea, and co-infections. (All rates of infection are available in the tables in the Appendix.) 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 35 Populations of Special Interest cont’d... The table to the left shows the number of co-infections in females, by age and race, for 2013-2015. African American females who are 15-19 years old have the highest number of co-infections ; the number of cases in this group comprises 21.14% of the total number of co-infections for this time period. This data suggests that African American adolescent girls should be a target of education about STDs; increased screening efforts for STDs would also be beneficial to this population. The table to the right shows the number of co-infections in males, by age and race, for 2013-2015. African American males who are 15-19 years old have the second highest number of co-infections; the number of cases in this group comprises 10.59% of the total number of co-infections for this time period. This data suggests that African American adolescent boys should also be the target of education about STDs; increased screening efforts for STDs would also be beneficial to this population. 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 36 Recommendations In order to further prevent the spread of STDs, it is vital that anyone who is sexually active is screened and tested. Per the CDC’s guidelines, screening and testing for Chlamydia and Gonorrhea are recommended for all sexually active women 25 years old and younger once a year; it is also recommended that women who are older but have many risk factors (such as new or multiple sex partners) should also be screened annually. Pregnant women 25 years old and younger should also be screened for both Chlamydia and Gonorrhea in order to protect the health of the child. Screening is also recommended annually for sexually active gay, bisexual, or any men who have sex with men (MSM); MSM who have multiple or anonymous sex partners are recommended to be screened more often (CDC 2016). For those who have been treated for an STD, it is recommended that they be rescreened three months after treatment. Screening and testing of sexual partners is also critical in order to stop the spread of infection. Recently, Ohio joined 47 other states who are participating in Expedited Partner Therapy (EPT). EPT is the practice of treating the partners of patients who have been diagnosed with Chlamydia or Gonorrhea without a healthcare provider seeing the partner first. The healthcare provider will give the patient medications that can be given to their sexual partner(s), making treatment of STDs much easier. However, the preferred method of partner treatment is partner referral through the patient. Chlamydia and Gonorrhea can also be prevented through other methods. Abstinence is the most reliable way to prevent any STD infection (i.e., not having anal, vaginal, or oral sex). Reducing the number of sexual partners, or participating in mutual monogamy will also greatly reduce the risk of STD infection. When male latex condoms are used correctly, they can be very effective at reducing the transmission of STDs. In order to reduce risk, latex condoms must be worn throughout the entirety of anal, oral, or vaginal intercourse. As stated earlier, adolescents and young adults have the highest risk of acquiring Chlamydia and Gonorrhea. Therefore, it is imperative that STD testing and treatment be increased among this population. The CDC has recommended several approaches to teen STD testing and treatment. There are several public school systems in the United States that have implemented education, testing, and treatment programs for STDs in adolescents (e.g., School District of Philadelphia, Chicago Public Schools, and San Diego Unified School District) (CDC 2016). It would be advantageous to consider a program like the ones listed in the Cleveland Municipal School District in attempts to lower the number of adolescents and young adults who are infected with Chlamydia and Gonorrhea. 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 37 Future Directions Currently, the Cleveland Department of Public Health (CDPH) is collaborating with the Cleveland Metropolitan School District to provide health education in schools and to promote reproductive health services offered. Reproductive health clinic nurses from CDPH have met with high school principals and school nurses in order to increase awareness among students of the services offered at reproductive health clinics. Recently, CDPH has employed adolescent peer educators to assist in the reproductive health clinics, promote services offered by the clinics, and offer peer-to-peer education in structured settings. Peer-to-peer education has occurred in forums such as after school programs, Halloween parties, HIV testing days, and a Reproductive Health Summit. Staff at the Reproductive Health Clinic have also worked with the CDPH program MomsFirst mobile unit in order to provide urine-based Gonorrhea and Chlamydia screening, health education outreach within the community, and the distribution of condoms one afternoon a week at various locations throughout the city. It is hoped that these programs can continue and expand in order to continue to service the need in this community. 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 38 Testing Centers Your risk of getting HIV from an infected partner is much higher if you already have an STD. HIV positive persons put their partner at risk when safe sex practices aren’t followed. Get smart. Get checked. Get treated. To find a testing center near you, visit https:// gettested.cdc.gov Local testing centers include: Cleveland Department of Public Health Cuyahoga County Board of Health McCafferty Health Center Health Center 4242 Lorain Ave. 5550 Venture Dr. Cleveland, OH 44113 Parma, OH 44130 (216) 651-5005 (216) 201-2001 J. Glen Smith Health Center 11100 St. Clair Ave. Northeast Ohio Neighborhood Health Services (NEON) Cleveland, OH 44108 8300 Hough Ave. (216) 249-4100 Cleveland, OH 44103 (216) 231-7700 Care Alliance Free Clinic of Greater Cleveland Downtown 12201 Euclid Ave. 1530 St. Clair Ave. Cleveland, OH 44106 Cleveland, OH 44114 (216) 721-4010 (216) 781-6724 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 39 2013 2013--2015 Cuyahoga County Sexually Transmitted Diseases Report: Chlamydia and Gonorrhea Created by: CDPH Office of Communicable Disease Surveillance and Epidemiology Data Source: Ohio Department of Health ODRS (Ohio Disease Reporting System) Date: July 8, 2016 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 40 Appendix 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 41 Appendix 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 42 Appendix 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 43 Appendix 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 44 Appendix 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 45 Appendix 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 46 Appendix 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 47 Appendix 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 48 Appendix 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 49 Appendix 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 50 Appendix 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 51 Appendix 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 52 Appendix 2013-2015 Cuyahoga County Chlamydia and Gonorrhea Surveillance Report 53