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AKI Case Patient Presentation Chief complaints are increasing SOB, tachypnea, fatigue, tiredness, anorexia and lower limb edema HPI M.Y.M is a 70 years old male patient with history of DM Type II, HTN, class II and HF Stage C and NYHAFC class II, admitted via ER due to HF decompensation subset II. History dates back to 3 days prior to admission when the patient started to complain from increase SOB , tachypnea , fatigue , tiredness , anorexia , lower limb edema which have been gradually worsening over the past 2 days and became worse over the last day prior to admission. PMH 1- Diabetes Mellitus type 2 (diagnosed since 1989; and is controlled) 2- HTN (diagnosed since 1985; and is uncontrolled) 3 HF stage C, NYHA –FC Class II (diagnosed since 2005; and is controlled) 4- Positive history of ASA and medical conditions induced gastric ulcer 5- Hypoglycemic episodes, 5 episodes last year, treated at home 6- Have his drugs most days of the week FH 1-Father with DM and HTN and died of AMI 2-Mother with HTN and breast cancer and died, free healthy history for his brothers and sisters 3- Married and lives at home with his wife 4- Limited social activity SH 1- Slightly limitation of physical activity, ordinary physical activity results in fatigue, palpitation, and dyspnea 2- He smoked 2-2 ½ pack per day for 30 years (60-75 pack/year) 3- Moderate caffeine consumption (2-4 cups per day) 4- History of alcohol use; patient is not asked PTA Furosemide (Lasix ®) tab PO, 40 mg once daily in the morning ASA (Aspirin ®) tab PO, 100 mg once daily Atorvastatin (Lipitor ®) tab PO 20 mg once daily ABT Candesartan (Atacand ®) tab PO, 8 mg once daily Metformin (Glucophage ®) tab PO, 850 mg three times daily NPH / Cryst-Insulin (Mixtard 70/30 ®) Inj SC, 30 U / 40 U / 30 U Omeprazole (Losec ®) tab PO, 20 mg once daily Current Meds Furosemide (Lasix ®) inj IV, 40 mg twice daily according to response, then when the patient is stable, start furosemide (Lasix ®) tab PO, 40 mg twice daily Candesartan (Atacand ®) Tab PO, 16 mg once daily Metformin (Glucophage ®) tab PO, 850 mg three times daily NPH / Cryst-insulin (Mixtard 70/30 ®) Inj SC, 30 U / 40 U/ 30 U ASA (Aspirin ®) tab PO, 100 mg once daily Atorvastatin (Lipitor ®) tab PO 10 mg once daily ABT Omeprazole (Losec ®) tab PO, 20 mg once daily Enoxaparin (Clexan ®) inj SC, 40 mg once daily ROS General Patient is agitated and confused VS BP 151/94, P 97, RR 24, T 36.8°C; Wt 83 kg, Ht 174 cm; oxygen saturation 84% Cardiovascular He dined chest pain, normal ECG, no palpitation, S3 & S4 gallop, elevated JVP, tachycardia Respiratory Wheezing, SOB, productive coughs and increase sputum volume. Inspiration crackles during lung expansion, tachypnea, (+) pleuritic chest pain, pleural effusion, decreased breath sound, use accessory respiratory muscles, paradoxical chest wall movements Gastrointestinal (+) constipation, (+) flatulence, anorexia, bloating, negative nausea and vomiting. No dysphagia, soft and nontender Allergies Skin rash was recorded after taking amoxicillin Genit / Rect He denied dysuria, urinary frequency, rectal exam deferred Dermatology Normal skin appearance and turgor Neurology He denied tremor, numbness, he only complained of headache Psychology Loss of appetite Endocrine None Hematology He denied of having bleeding gums, and bruising Labs Na 136 mEq/L Hgb 11.2 g/dL AST 29 IU/L Ca 9.2 mg/L K 3.5 mEq/L Hct 34.1% ALT 22 IU/L Mg 1.92 mg/L T. bili 0.8 mg/dL Phos 4.3 mg/dL Alb 3.6 g/dL LDL-C 90 mg/dL Cl 103 mEq/L HCO3 22 meg/l Plt 165 × 103/mm3 WBC 9.4 × 103/mm3 BUN (day 1) 29 mg/dL Neutrophil sig% 65.3 × 103/mm3 Basophils% 0.23 × 103/mm3 BUN (day 2) 35 mg/dL Monocytes% 3.9 × 103/mm3 Glu 240 mg/dL RBC 6.2 × 106/uL HDL 34 mg/dL Eosinophils% 0.23 × 103/mm3 TG 190 mg/dL Plt 165 × 103/mm3 SCr (day 1) 0.96 mg/dL SCr (day 2) 1.31 mg/dL Scores / Stages / Classes Pain score = 1, VTE score =3, HF stage C, NYHA-FC class II, HF exacerbation subset II (Warm & Wet HF), LVEF = 33%