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Chapter 3: Cell Division 3.3 MITOSIS 1 Describe the four stages of the mitotic cell division Explain the behavior of the chromosomes at each stage Describe briefly the cytokinesis process Compare the cell division in animal and plant State the significance of mitosis. 2 MITOSIS COMPARISON OF CELL DIVISION STAGES CHROMOSOMES BEHAVIOUR CYTOKINESIS PROCESS PLANT ANIMAL SIGNIFICANCE 3 CYTOKINESIS The division of cytoplasm KARYOKINESIS The division of nucleus 4 Consists of 4 phases: Mitosis Telophase 5 PROPHASE • Chromatin become more tightly coiled & condensed into chromosomes that consist of 2 sister chromatids. 6 PROPHASE aster Mitotic spindle begins to form Centrosomes move away from each other to the opposite poles Nucleolus disappear Nuclear envelope disintegrates 7 METAPHASE Non-kinetochore microtubule Kinetochore microtubule • Centrosomes are at opposite poles of the cell. • The sister chromatids arranged themselves at metaphase plate 8 ANAPHASE • centromeres split centromere • The sister chromatids separate and move apart towards the opposite poles 9 TELOPHASE Nucleolus reforms in each new nucleus • Chromatids reach their respective poles. • Chromatids uncoil and lengthen invisible again. Nuclear envelope forms spindle fibers disintegrate 10 Prophase anaphase Metaphase Telophase 11 CYTOKINESIS IN ANIMAL CELL • By cleavage process • Begin with the appearance of cleavage furrow. • The furrow is a contractile ring of actin microfilaments associated with myosin • The actin microfilaments interact with the myosin Causing ring to contract • Cleavage furrow deepens until parent cell pinched into two 12 CYTOKINESIS IN PLANT CELL • By cell plate formation. • Vesicles- containing cell wall material (cellulose) derived from golgi apparatus • Move to the middle of the cell. • Combine to form cell plate. • Cell plate enlarges • fuses with the parent cell plasma membrane • Make 2 new cell. 13 CYTOKINESIS IN ANIMAL CELL • By cleavage process • Begin with the appearance of cleavage furrow. • The furrow is a contractile ring of actin microfilaments associated with myosin • The actin microfilaments interact with the myosin Causing ring to contract • Cleavage furrow deepens until parent cell pinched into two 14 CYTOKINESIS IN PLANT CELL • By cell plate formation. • Vesicles- containing cell wall material (cellulose) derived from golgi apparatus • Move to the middle of the cell. • Combine to form cell plate. • Cell plate enlarges • fuses with the parent cell plasma membrane • Make 2 new cell. 15 16 Differences between mitosis in plant and animal cells Animal Cells 1. Have centrioles Plant Cells 1. lack of centrioles. 2. Cytokinesis occurs 2. Cytokinesis occurs by the constriction of by the growth of a microtubules – cell plate through the cleavage furrow. fusion of vesicles. 17 **** go back and find out more…….. Significance of mitosis 1. Genetic stability • • • Maintain same number of chromosomes as a parental cell. Daughter cell are genetically identical to the parental cell no variation in genetic information 18 2. Growth • growth in multicellular organisms. 3. Cell replacement • Replacement of damaged cells and tissues 19 4. Regeneration Some animal are able to regenerate whole parts of the body 20 5. Asexual reproduction production of new individuals of a species by one parent organism. 21 22