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Optic Nerve Hypoplasia Optic Nerve Hypoplasia is the underdevelopment of the optic nerve during pregnancy. The majority of the time Optic Nerve Hypoplasia is bilateral. It is congenital, stable and not genetic. With Optic Nerve Hypoplasia photophobia and a nystagmus may occur. As the brain matures there may be a mild improvement in visual function and in some cases, reduced nystagmus may also occur. A person with Optic Nerve Hypoplasia has optic nerves which are small and poorly developed. Instead of having over 1 million connections (nerve fiber) from each eye to the brain, people with Optic Nerve Hypoplasia have far fewer connections. Vision can range 20/20 to complete blindness, or no light perception. Affected eyes also show a visual field deficit. Managing uncomplicated cases require patient education and protective eyewear. When one eye is affected more than the other, an ophthalmologist may recommend a trial of patching the stronger eye, since the visual loss may be due to amblyopia. References (Jan 5, 2009). Optic Nerve Hypoplasia (ONH)-General Information. Retrieved July 1, 2009, from The MAGIC Foundation Web site: http://www.magicfoundation.org/printpage.php?LEVEL=101&ID=116&ELEMENT=docs. Chan, Jane (2007). Optic Nerve Disorders. New York, NY : Springer. Optic Nerve Hypoplasia. Retrieved July 12009, from Handbook of Ocular Disease Management Web site: http://www.revoptom.com/handbook/sect6i.htm Pediatric Visual Diagnosis Fact Sheet: Optic Nerve Hypoplasia. Retrieved July 1, 2009, from Blind babies foundation Web site: http://blindbabies.typepad.com/parents_and_caregivers/files/fact_sheet_optic_nerve_hyp oplasia.pdf. Verderber, M.D., Lisa (Sept./Oct. 1996). The Doctor Is In: Optic Nerve Hypoplasia. Visually Impaired Preschool Services of, Louisville Kentucky.