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The Chemicals of Life Carbon “The element of Life” Base element for many macromolecules in the body Carbon is a small element that can form 4 stable covalent bonds with other atoms (look at valence electrons). The number of covalent bonds an atom can form is called its bonding capacity. Carbon can bond to other carbon atoms in straight chains, branched chains or rings. Biological Macromolecules Our body has four major macromolecules that it uses. Macromolecule – large molecules that are sometimes composed of a great number of repeating subunits. There are four major classes: - carbohydrates - lipids - proteins - nucleic acids Macromolecule Subunit complex carbohydrate (starch) Lipid (triacylglycerol) simple sugar (glucose) protein Nucleic acid (DNA and RNA) Glycerol and fatty acids (not really subunits) Amino acids nucleotides Complicated carbohydrates, proteins and nucleic acids are polymers, meaning that they are long chains of smaller subunits. Condensation Reactions Macromolecules are all made in the same way, a condensation reaction (dehydration synthesis reaction). Creates covalent bonds between two subunits. It removes hydrogen from one subunit and an OH- from the other subunit. Condensation reactions are called anabolic reactions because they make one large molecule from smaller subunits. Hydrolysis Reactions Sometimes cells break things apart. Catabolic reactions break things apart (digestion). Hydrolysis reactions use a water molecule to break apart a covalent bond that holds subunits together. The water molecule provides an H atom to one subunit and an OH- group to the other. Hydrolysis and condensation reactions require the use of enzymes (special proteins). Enzymes are catalysts, which speed up chemical reactions and do not get consumed in the chemical reaction. Metabolism is the sum of all anabolic and catabolic processes in a cell or organism. * We will discuss metabolism and enzymes later