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Unit D – Human systems Chapter 8 – Nutrients, Enzymes and the Digestive System Text pages 240 - 279 Essential Nutrients • Chemicals of life: – Proteins (PRO) • Structural components of the cells • – Carbohydrates (CHO) • Main source of _______ for cells • Structural material of plant cell walls – Fats/lipids (FAT) • Energy storage compound • Structural component of cell membrane Essential nutrients – Vitamins and minerals • Help in chemical reactions (ex. Coenzymes) • Often found in complex chemicals – Nucleic acids • Genetic material that directs cell activity • Made up of Essential Nutrients • Food can be classified into three major groups of nutrients: 1. (CHO) 2. (PRO) 3. Fats or lipids 8.1 - Essential Nutrients - Carbs Carbohydrates: • Primary fuel source for cells • Carbohydrates contain C, H and O • (C:H:O is a ratio) • ‘ose’ suffix. • The human body is not able to make Carbs so you rely on gaining carbs from your diet • Classified by # of sugar units they have – 3 types of sugar: 1. Monosaccharides – 1 sugar unit 2. Disaccharides – 2 sugar units 3. Polysaccharides – many sugar units 8.1 - Essential Nutrients - Carbs 1. Monosaccharides (simple sugars) • Examples: • isomers... same molecular formula, different structural arrangements. a. – energy source for cellular respiration, soluble and easy to transport. b. – very sweet tasting, used to build more complex molecules. c. Galactose – not found ‘free’ in nature – always bonded to another monosaccharide. (Ex. lactose is glucose + galactose) 8.1 - Essential Nutrients - Carbs 2. Disaccharides: • (double sugars) • formed by dehydration synthesis. 8.1 - Essential Nutrients • Three disaccharides are: 1. Sucrose (sugar cane) – – (glucose + fructose) 2. Maltose (malt sugar) – found in germinating barley – (glucose + ) 3. Lactose (milk sugar) – (glucose + ) 8.1 - Essential Nutrients 3. • • • • • Polysaccharides Largest sugars Also formed by dehydration synthesis. These sugars are broken down by our digestive system by hydrolysis into simple sugars and then absorbed into the body. Poly di mono (then absorbed) 8.1 - Essential Nutrients - Carbs Polysaccharides: 3 types: A. Starch: – produced by plants – Examples: B. Cellulose: supplies ‘roughage’ because not easily digested – Examples: C. Glycogen: extra glucose is converted into glycogen for storage 8.1 - Essential Nutrients - Carbs • Carbohydrates • digested to simple sugars – absorbed in the 8.1 - Essential Nutrients - Lipids • Lipids are made up of the same elements as carbohydrates, but cannot be broken down into H2O. • Since fats are non-soluble in water, they cannot be dissolved in the blood. • What does bile do? • Functions: Lipids – Storage of energy for when glycogen stores are used up – Components in cell membranes – – – Raw materials for the synthesis of hormones and other important chemicals Lipids 1. Triglycerides – glycerol and 3 fatty acids – If solid at room temp = – Saturated fatty acids = only single bonds exist between carbon atoms – If liquid at room temp = – Polyunsaturated = double bonds between some of the carbon atoms in a fatty acid – Which fats are easier to break down? 8.1 - Essential Nutrients -lipids • Saturated fats: – animal origin, solid at room temp. – Examples: • Unsaturated fats: – plant origin, liquid at room temp. – Examples: • _____________: is hardening of the arteries due to a build up of fat. Lipids 2. Phospholipids – phosphate group bonded to the glycerol backbone – 3. Waxes – long-chain fatty acids joined to long-chain alcohols or carbon rings – Phospholipids Liposome Proteins • Used to form the structural parts of a cell • Composed of building blocks called amino acids – Amino group (NH2) – Carboxyl group (COOH) – Different amino acids (AA) – the “R” group – 20 AA to build from Proteins • Proteins are found as: – Cytoplasmic organelles (mitochondria, ribosomes) – Muscles – Nerves – Skin – Hair – Antibodies – Enzymes 8.1 - Essential Nutrients - Proteins Functions of Proteins: a) b) proteins are necessary for a healthy immune system (enzymes, hormones) c) regulate acid/base as protein acts as a buffer for H+ concentrate. Proteins • The sequence of AA is determined by the genes located on your chromosomes • Joining AA involves removal of water and formation of a peptide bond • Chains of AA are called polypeptides Protein Dehydration Synthesis Source: http://img.sparknotes.com/content/testprep/bookimgs/sat2/biology/0003/peptide.gif Proteins • The body is able to synthesize many of the AA if they are not found in the diet • BUT, there are 8 AA, called essential amino acids, that you can only get from food • Structure: Proteins – The polypeptide chain(s) are folded into 3-D shapes – – Four levels of protein structure: • • • • Primary Secondary Tertiary Quaternary Proteins Structure: • Primary structure – the sequence of AA in the chain • ____________– folds and coils that occur due to hydrogen bonding (into helical coils or pleated sheets) • Tertiary structure – • Quaternary structure – two or more polypeptides joined together (ex. Hemoglobin is made up of 4 polypeptides) Protein Structure Source: http://upload.wikimedia.org/wikipedia/en/thumb/a/a6/Protein-structure.png/300px-Protein-structure.png Proteins • Denaturation and Coagulation: – Exposing a PRO to excess ______, ________ or a change in pH will alter its ______ – Denaturation – the process that occurs when the bonds of a protein molecule are disrupted causing a TEMPORARY change in shape • Alters their biological activity – _________– the process that occurs when the bonds of a protein molecule are disrupted causing a PERMANENTchange in shape