Download TEST:VBT23-04 ENG Varianta:originál + the statement is correct

TEST:VBT23-04 ENG Varianta:originál
+ the statement is correct
- the statement isn´t correct
1. Which of the following statements are true?
1) - Hydrogen peroxide is oxidized to hydroxide (OH-) during Fenton´s reaction
2) + Catalase catalyzes the decomposition of hydrogen peroxide to water and oxygen
3) + An anion has more electrons than protons
4) - Transferrin binds transition elements (Fe and Cu) and therefore it does not act as
an antioxidant
-----------------------------------------------------------------------------------------2. Select correct statements
1) - Some male individuals with azoospermia have a deletion of AZF located on the X
chromosome
2) + SRY gene on the short arm of Y chromosome determines the male sex
3) - There are different (heterologous) segments in the pseudoautosomal regions of
human X and Y chromosomes
4) - Male sex is heterogametic and female sex is homogametic at the Abraxas type of
sex determination
-----------------------------------------------------------------------------------------3. Select correct statements
1) - Sterility is the inability to carry and give birth to a viable child while maintaining the
ability to conceive
2) + Secondary infertility means the inability to conceive a child after a previous
successful pregnancy
3) - Human kind is one of the species with a high reproductive capacity
4) - During the intracytoplasmic sperm injection one sperm is injected into the
perivitelline space of the egg
-----------------------------------------------------------------------------------------4. Which of the following statements are true?
1) - Genes of all transposons encode reverse transcriptase
2) + The enzyme responsible for transposition is called transposase
3) - Somatic hybridization, fusion of cells, is ranked among the types of vertical
transfer of genetic information
4) - All cell organelles originated from invaginations of biomembranes
-----------------------------------------------------------------------------------------5. Which of the following is correct?
1) - Current phylogenetic trees are constructed based on comparative physiology,
biochemistry and embryology
2) + The first mammals appeared on the Earth about 250 million years ago
3) - Most of the genetic information of primates and humans is different
4) - Domains Bacteria, Archaea and Eukaryota have evolved independently as
separate evolutionary branches
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6. Select correct statements
1) - Poles of the mitotic spindle move apart in anaphase A
2) - Reintegration of the nuclear envelope in the telophase is based on the
phosphorylation of lamins
3) + Polar microtubules of mitotic spindle are not attached to chromosomes
4) + Separation of sister chomatids starts anaphase
-----------------------------------------------------------------------------------------7. Which of the following statements are true?
1) + Heterodimer of Fos and Jun proteins is the transcription factor AP-1
2) + Expression of a mediating protein is not required for the induction of expression
of primary response genes
3) + Primary response genes code for transcription factors
4) - c-ras is a primary response gene
-----------------------------------------------------------------------------------------8. Select correct statements
1) - Hayflick limit of cancer cells is higher than Hayflick limit of normal cells
2) + Hayflick limit expresses the life span of somatic cells of certain organism
3) - Hayflick limit of human embryonic cells is 500 cell cycles
4) - Hayflick limit of human somatic cells is 200 years
-----------------------------------------------------------------------------------------9. Select correct statements
1) - Initiator caspases are caspase-9, caspase-8 and caspase-6
2) + Caspase-1 is an inflammatory caspase
3) - Initiator caspases start apoptosis by cleaving death substrates
4) - Caspases are serine-threonine kinases
-----------------------------------------------------------------------------------------10. Select correct statements
1) + Proteins of the Bcl-2 family contain characteristic BH domains
2) - Puma is not a member of the Bcl-2 family
3) + Bax is a proapoptotic protein of the Bcl-2 family
4) - Proteins of the Bcl-2 family are extracellular apoptotic signals
-----------------------------------------------------------------------------------------11. Which of the following is correct?
1) + Gene hst-1 codes for a growth factor
2) + Gene for the B chain of PDGF is c-sis
3) - v-Src is not nonreceptor tyrosine kinase
4) - Oncogenes can not code for receptor tyrosine kinases
-----------------------------------------------------------------------------------------12. Which of the following statements are true?
1) + Physiological renewal of endothelial cells is based on the proliferation of
differentiated cells
2) - Fully differentiated cells do not proliferate
3) + Stem cell is a progenitor cell
4) - Progenitor cell is differentiated cell
------------------------------------------------------------------------------------------
13. Select correct statements
1) - Procaryotic cell has 80S ribosomes
2) - Procaryotic cell has 100-400 genes
3) + Transcription and translation are separated in eucaryotic cells
4) - Procaryotic cell has a nucleus
-----------------------------------------------------------------------------------------14. Out of the following choose correct statements
1) + Morphogenesis is the term expressing the process of structure development
2) + Epithelio-mesenchymal interactions are the common mechanism of structure
formation during development/ontogenesis
3) + Cell-signalling and cell-interaction are involved in organ development
4) - Embryo is most sensitive during blastogenesis
-----------------------------------------------------------------------------------------15. Which of the following statements are true?
1) + Endometrial epithelium regenerates from the bottom (base) of endometrial glands
2) + Endometrium is reduced to the zona basalis during menstrual phase
3) + Follicular and thecal cells have to cooperate during ovarial hormone synthesis
4) + Follicular cells develop into granulosa-lutein cells after ovulation
-----------------------------------------------------------------------------------------16. Which of the following is correct?
1) + Sperm flagellum contains an axial complex (9 duplets of microtubules on the
periphery and one pair in the middle)
2) - Zonal reaction during fertilization is a process taking place in the periphery of an
oocyte
3) + Zygote uses centrioles of a sperm cell for its first division
4) + Capacitation and acrosomal reaction are necessary for fertilization
-----------------------------------------------------------------------------------------17. Which of the following is correct?
1) + One signal molecule is usually unable to activate the signal pathway
2) + Higher concentration of morphogens on the left side during the establishment of
the left-right orientation is achieved by a movement (beating) of kinocilia present on
primitive node cells
3) + Morphogen can be e.g. a growth factor
4) + Cells can express different proteins on different cellular sides (anterior and
posterior)
-----------------------------------------------------------------------------------------18. Which of the following statements are true?
1) + Blastocyst can implant itself in the oviduct under pathological conditions
2) - Embryoblast divides into epiblast and trophoblast
3) - Syncytiotrophoblast is in direct contact with amnion
4) + Exocoelom, or primitive yolk sac, is surrounded by exocoelomic Heuser´s
membrane
------------------------------------------------------------------------------------------
19. Which of the following statements are true?
1) + Germ layers originate from epiblast
2) - Primitive streak induces the neural plate to develop into the brain
3) + Development of axial structures of the trunk is formed by the activity of caudal
morphogenetic system
4) + Neuroporus anterior (rostral) closes during the 4th week of development (25ED)
-----------------------------------------------------------------------------------------20. Select correct statements
1) - Segmentation typically occurs in mesoderm and endoderm
2) + Rapid growth of the embryo, particularly of its brain and spinalcord, results in
folding
3) - Somite differentiation results in the formation of a sclerotome, nephrotome and
myotome
4) + Cell population of melanocytes in the epidermis of the skin is a neuroectodermal
derivate
-----------------------------------------------------------------------------------------21. Select correct statements
1) - Epidermal cells live for approximately one year
2) + Cellular proteins renew more slowly during senescence
3) - Number of mitochondria in cardiomyocytes (cells of the heart) decreases during
senescence
4) + Cells have the highest content of water during the embryonic period
-----------------------------------------------------------------------------------------22. Which of the following statements are true?
1) + Warfarin is a strong teratogen
2) + Effect of teratogens is also modified by the genetic background
3) + In embryotoxicity testing we administer the tested substance during
organogenesis
4) + Drugs affecting proliferation are probably teratogens