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Transcript
SBI 4U – Homeostasis

Hormone
1.
ADH (antidiuretic hormone)
2.
Oxytocin
STHRH / GHRH
(somatotropin/growth hormone releasing
hormone)
4. STH/GH (somatotropin/growth hormone)
5. CRH (corticotropin releasing hormone)
3.
6.
ACTH (corticotropin)
7.
Glucocorticoid (eg. cortisol)
8.
TRH (thyrotropin releasing hormone)
9.
TSH (thyroid stimulating hormone)
Gland
posterior pituitary
Target
kidneys
posterior pituitary
-
hypothalamus
uterus and
mammary
glands
anterior pituitary
anterior pituitary
hypothalamus
anterior pituitary
most cells
anterior pituitary
adrenal cortex
-
adrenal cortex
liver and
immune system
hypothalamus
anterior pituitary
anterior pituitary
thyroid
thyroid
body cells
hypothalamus
anterior pituitary
anterior pituitary
Females:
ovaries, Males:
testes
anterior pituitary
Females: follicle
Males: testes
hypothalamus
mostly anterior
pituitary, but many
other cells
anterior pituitary
mammary
glands
thyroid
bone cells,
kidney
parathyroid
mostly bone and
kidney
beta cells of the
Islets of Langerhans
in pancreas
skeletal
muscles, liver,
fat cells
10. Thyroid hormones (T3, T4)
11. GnRH (gonadotropin releasing hormone)
12. FSH (follicle stimulating hormone)
13. LH (luteinizing hormone)
14. PRLRH (prolactin releasing hormone)
15. Prolactin
16. Calcitonin
17. PTH (parathyroid hormone)
18. Insulin
-
-
Primary Function
increases water reabsorption in
nephron tubules
initiates contractions for childbirth
triggers milk release in lactating
women
stimulates synthesis and secretion
of GH
promotes growth
stimulates release of ACTH
stimulates release of hormones
involved in stress response, such
as glucocorticoids,
mineralocorticoids
- stimulate conversion of protein
and fat into glucose
- suppress inflammatory response
- stimulates release of TSH and
PRL
- stimulates release of thyroxin (T4)
- increases metabolic rate
- increases heart rate and strength
of heart beat
- increases release of FSH and LH
Females: stimulates follicle to release
estrogens
Males: stimulates spermatogonia to
produce sperm
Females: stimulates follicle to release
estrogens and develops into corpus
luteum
Males: stimulates interstitial cells to
release testosterone
- stimulates release of PRL
- during pregnancy helps in
preparation for future milk
production
- after pregnancy promotes
synthesis of milk
- suppresses osteoclasts (bone cell
digesting cells) decreasing
calcium and phosphorus levels in
blood
- decreases reabsorption of Ca and
P in kidneys
- regulates calcium and phosphorus
levels in ECF
- extremely important in humans
- stimulates cells take up glucose
and convert it to glycogen or fat,
decreasing blood glucose
19. Glucagon
20. Somatostatin
21. Melatonin
22. Thymosin
alpha cells of the
Islets of Langerhans
in pancreas
hypothalamus
liver
-
anterior pituitary
pineal
thymus
not well
understood
lymph nodes
-
adrenal cortex
kidney
-
23. Mineralocorticoid (eg. aldosterone)
24. Adrenalin
adrenal medulla
many cell types
-
ovaries of mature
females
many target
tissues
-
25. Noradrenalin
-
26. Estrogen
27. Progesterone
corpus luteum
and placenta
endometrium
-
trophoblast of a
blastocyst (embryo)
corpus luteum
-
28. HGC (human chorionic gonadotropin)
-
29. Testosterone
Interstitial cells of
testes
many cell types
-
atria of heart
kidneys
-
liver
muscle and
bone
angiotensinogen
30. ANH (atrial natriuretic hormone)
31. Somatomedin
kidney
32. Renin
33. Erythropoietin (EPO)
34. Gastrin
35. Secretin
-
kidney
bone marrow
-
stomach and
duodenum
gastric cells of
stomach
-
duodenum
pancreas
-
stimulates conversion of glycogen
into glucose, increasing blood
glucose
inhibits release of GH
inhibits release of TSH
Regulates sleep/wake cycles
(circadian rhythm)
stimulates immunological activity
of lymphoid tissue
promotes reabsorption of Na+ ions
– water follows which increases
blood volume and blood pressure
heart beats faster and stronger
blood shunted away from skin and
viscera to the skeletal muscles,
brain, coronary arteries
rise in blood sugar
increased metabolism
pupils, bronchi dilate
pilomotor response
prepare body for immediate and
vigorous action
responsible for sexual maturation
of women
participate in monthly menstrual
cycle
participate in pregnancy
prepares endometrium for
possible pregnancy
secretion is maintained if
pregnancy occurs
prevents deterioration of corpus
luteum after fourth week and
allows pregnancy to continue
commonly tested for in pregnancy
tests
develops secondary sexual
characteristics
sperm production
regulates blood pressure by
causing kidneys to excrete more
salt
insulin-like growth hormone
converts angiotensinogen into
angiotensin II
this causes several changes with
result in increased blood pressure
stimulates production of red blood
cells (erythrocytes)
stimulates the exocrine cells of
stomach to secrete gastric juice
stimulates pancreas to release
bicarbonate ions into pancreatic
fluid