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• Main Function: It releases hormones (chemical messengers) into the blood to signal other cells (target cells) to behave in certain ways. It is a slow but widespread form of communication. Consists of: Endocrine glands Release hormones into the bloodstream. Hormones are chemicals released in one part of the body that travel through the bloodstream and affect the activities of cells in other parts of the body. Interaction of Glands The hypothalamus is located in the brain and controls the release of hormones from the pituitary gland. It is an important link between the endocrine and nervous systems. Interaction of Glands The brain and glands work together to maintain homeostasis through a process called negative and positive feedback mechanisms. Endocrine System Pituitary Gland Pituitary Gland Function: It secretes nine hormones that control all other endocrine glands. -produces human growth hormone - Disorders: Too much growth hormone can result in a condition called gigantism. Robert Wadlow Endocrine System Pituitary Gland Thyroid Gland Thyroid Gland • Hormone: Thyroxin • Function: plays a major role in the regulation the body’s metabolism. • Disorders: Hyperthyroidism-too much thyroxin; fast metabolism Hypothyroidism- too little thyroxin; slow metabolism Goiter-lack of iron in diet, no thyroxin secretion, enlargement of thyroid gland Endocrine System Pituitary Gland Adrenal Glands Thyroid Gland Adrenal Gland • Functions: -The adrenal glands release Adrenaline in the body that helps prepare for and deal with stress. -Also regulates kidney function. Endocrine System Pituitary Gland Thyroid Gland Ovaries Adrenal Glands Ovaries • Functions: – Pair of reproductive organs found in women that produce eggs. – Also secrete estrogen and progesterone, which control ovulation and menstruation. Endocrine System Pineal Gland Pituitary Gland Parathyroid Gland Thyroid Gland Pancreas Ovaries Thymus Adrenal Glands Testes Testes • Functions: – Pair of reproductive glands that produces sperm. – Also secrete Testosterone to give the body its masculine characteristics. Endocrine System Pineal Gland Pituitary Gland Parathyroid Gland Thyroid Gland Pancreas Ovaries Thymus Adrenal Glands Testes Pancreas [Islets of Langerhans] Insulin: Reduces levels of glucose in the blood • conversion of glucose to glycogen •promoting glucose absorption and use by body cells Glucagon: Increases levels of glucose in the blood • causes liver to convert glycogen to glucose Negative Feedback • Is a type of self-regulation associated with endocrine regulation Functions like a thermostat. Only activated when there is a need. Shuts off once that need has been met. Negative Feedback A B Glycogen If there is too much glucose in the blood, insulin converts some of it to glycogen Glucose in the blood Glycogen If there is not enough glucose in the blood, glucagon converts some glycogen into glucose. Glucose in the blood Glucose Concentration Glucose levels rise after a meal. Insulin is produced and glucose levels fall to normal again. Normal Meal eaten Time Failure of Homeostasis: Diabetes: [Islets of Langerhans] Islets of Langerhans don’t make enough insulin • Glucose in blood can’t be stored as glycogen •Blood levels of glucose INCREASE Glycogen The glucose in But there is no Glucose the blood insulin to convert concentration increases. it into glycogen. rises to dangerous levels. Glucose in the blood Glucose Concentration Glucose levels rise after a meal. Diabetic Insulin is not produced so glucose levels stay high Meal eaten Time Positive Feedback • Enhances an existing response – Child birth Interaction of Glands The feedback the brain gets is from the information it collects as the hypothalamus monitors the bloodstream. Using this information, the brain knows what hormones to start and stop releasing. Main Function: This communication system controls and coordinates functions throughout the body and responds to internal and external stimuli. Our nervous system allows us to feel pain. Consists of: brain, spinal cord, nerves and sense organs Sense Organs: Eyes, Skin, Ears, Nose & Tongue A nerve is an organ containing a bundle of nerve cells called neurons. Neurons carry electrical messages called impulses throughout the body. Picture shows hundreds of severed neuron axons dendrite Axon cell body cell body TYPICAL MOTOR NEURON synapse muscle tissue Because neurons never touch, chemical signalers called neurotransmitters must travel through the space called synapse between two neurons. Neurotransmitters (pink spheres) Synapse (gap) The message is transferred when RECEPTORS receive neurotransmitters. Parts of a Neuron 1. Cell body: contains nucleus & most of the cytoplasm 2. Dendrites: projections that bring impulses into the neuron to the cell body. 3. Axon: long projection that carries impulses away from cell body travels dendrite towards axon 1 2 3 Parts of a Neuron 1. Cell body: contains nucleus & most of the cytoplasm 2. Dendrites: projections that bring impulses into the neuron to the cell body. 3. Axon: long projection that carries impulses away from cell body 1 2 3 Sensory Neuron Interneuron Synapse Synapse Motor Neuron Interneuron Synapse Motor Neuron Sensory Neuron Muscle Contracts Sensory Neuron carry impulses from sense organs to spinal cord & brain Fun Fact: Where can the largest cells in the world be found? The giraffe’s sensory and motor neurons! Some must bring impulses from the bottom of their legs to their spinal cord several meters away!! Interneuron -processes impulses in brain and spinal cord - connect sensory and motor neurons Motor Neurons carry impulses from the brain & spinal cord to muscles & glands Axon End Axons branching out to muscle fibers • Nerves work together with muscles for movement. An impulse begins when one neuron is stimulated by another neuron or by the sense organs. • The impulse travels down the axons of Sensory neurons to the brain cells called Interneurons. • The brain will then send an impulse through motor neurons to the necessary muscle or organs, telling it to contract. A reflex is an involuntary response that is processed in the spinal cord not the brain. Reflexes protect the body before the brain knows what is going on. Reflex Arc Reflex Arc Path reflex impulse travels Sense Receptor Muscle/Gland Sensory Neuron Motor Neuron S P I N A L C O R D Human Nervous System Central Nervous System [CNS] Brain & Spinal Cord Peripheral Nervous System [PNS] Nerves branching from the brain and spinal cord Consists of: Brain and Spinal Cord Cerebrum brain Cerebellum Medulla Oblongata Spinal Cord Cerebrum Voluntary or conscious activities of the body-learning, judgment Cerebellum Coordinates and balances the actions of the muscles Medulla Oblongata (Brain Stem) Spinal Cord Controls involuntary actions like blood pressure, heart rate, breathing, and swallowing The main communications link between the brain and the rest of the body Consists of: Sensory division and Motor division -includes all sensory neurons, motor neurons, and sense organs Subdivisions of PNS Somatic Nervous System: • voluntary control • responsible for conscious body movement Autonomic Nervous System: • no voluntary control • serve internal organs • involved with: heart rate blood flow breathing movements digestive system gland secretions Autonomic Nervous System: Sympathetic: “fight or flight” speed up body functions Parasympathetic: slow down body functions Concept Map The Nervous System is divided into Central nervous system Peripheral nervous system Motor nerves which consists of that make up Somatic nervous system Autonomic nervous system which is divided into Sympathetic nervous system Parasympathetic nervous system Sensory nerves Nervous vs. Endocrine System Similarities: • both involved with maintaining homeostasis • both secrete chemicals Endocrine System: hormones Nervous System: neurotransmitter Differences: • NS response is much faster than ES response • ES response lasts longer than NS response • Nerve impulse transmitted by neuron, hormones transported by the blood