* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Download SHORT CV - Diabetes Research Institute
Survey
Document related concepts
Transcript
JAY S. SKYLER, MD, MACP CURRICULUM VITAE Professor of Medicine, Pediatrics & Psychology Division of Endocrinology, Diabetes, & Metabolism – Department of Medicine University of Miami Leonard M. Miller School of Medicine Deputy Director for Clinical Research and Academic Programs, Diabetes Research Institute, University of Miami Member, Interdisciplinary Stem Cell Institute, University of Miami Adjunct Professor of Pediatrics, Barbara Davis Center for Childhood Diabetes, University of Colorado BIOGRAPHICAL INFORMATION 1. PERSONAL a. b. c. d. e. f. g. Date: Full Name: Home Phone: Office Phone: Fax Numbers: E-Mail: Office Address: h. Office Location: i. Home Address: j. k. l. m. n. o. p. Status: Current Rank: Citizenship: Health: Born: Marital Status: Children: September 2015 Jay Samuel Skyler (305) 361-8035 (305) 243-6146 (305) 243-4484; (425) 988-9818 [email protected] University of Miami Diabetes Research Institute P.O. Box 016960 (D-110) Miami, Florida 33101-6960 Diabetes Research Institute, Suite 3061 1450 N.W. 10th Avenue Miami, Florida 33136-1011 445 Grand Bay Drive #1206 Key Biscayne FL 33149-1910 Full-time Tenured Professor of Medicine, Pediatrics & Psychology United States of America Excellent February 14, 1947 - Philadelphia Pennsylvania Married – Mercedes Armas Bach – 8/9/03 Jennifer Anne Skyler, Born: 2/12/81 Alexandra Regina Bach, Born: 4/23/81 Marcus Richard Bach, Born 8/22/83 2. EDUCATION Primary and Secondary Schools, Philadelphia, Pennsylvania B.A., Central High School: June 1964 (222nd Graduating Class) B.S. in Science (Magna Cum Laude), Pennsylvania State University: September 1967 (Cooperative Five-Year Program in Medicine, Pennsylvania State University and Jefferson Medical College) M.D., Jefferson Medical College: June 1969 Visiting Student, Department of Cardiology, University of Glasgow at the Royal Infirmary, Glasgow, Scotland: Summer 1967 Alliance for Academic Internal Medicine Executive Leadership Program, Cambridge, Massachusetts: Summer 2003 Harvard Business School Executive Education Program, Making Corporate Boards More Effective: Winter 2006 Stanford Law School Directors Course: June 2009 Jay S. Skyler Page 2 Curriculum Vitae 3. POST-DOCTORAL EDUCATION Intern and Resident, Department of Medicine (James B. Wyngaarden, M.D., Chairman), Duke University Medical Center: July 1969-June 1971 Fellow in Endocrinology and Metabolism (Harold E. Lebovitz, M.D., Division Chief), Department of Medicine, Duke University Medical Center: February 1971-June 1973 Fellow in Medicine, Medical Research Training Program (Nicholas M. Kredich, M.D., Program Director), in the Laboratory of Molecular Animal Virology (Hans J. Zweerink, Ph.D., Laboratory Director), Department of Microbiology and Immunology (Wolfgang K. Joklik, Ph.D., Chairman), Duke University: September 1971September 1972 Staff Associate, Section on Biochemical Pharmacology (Walter M. Lovenberg, Ph.D., Laboratory Chief), Hypertension-Endocrine Branch (Frederic C. Bartter, M.D., Branch Chief), National Heart and Lung Institute (Donald S. Fredrickson, M.D., Scientific Director), National Institutes of Health: July 1973-June 1975 4. BOARD CERTIFICATION AND LICENSURES National Board of Medical Examiners - Diplomate: July 1, 1970 American Board of Internal Medicine - Diplomate, Internal Medicine: June 21, 1972 American Board of Internal Medicine - Diplomate, Endocrinology and Metabolism: October 6, 1973 Pennsylvania Board of Medical Examiners (Inactive) North Carolina Board of Medical Examiners (Inactive) District of Columbia Board of Medical Examiners (Inactive) Florida Board of Medical Examiners 5. PROFESSIONAL EXPERIENCES Academic Appointments Associate in Medicine, Duke University School of Medicine: July 1972-August 1975 Associate in Community Health Sciences, Duke University School of Medicine: September 1972-June 1975 (**Leave of Absence from Duke University: July 1973-June 1975) Clinical Investigator, Hypertension-Endocrine Branch, National Heart and Lung Institute, National Institutes of Health: July 1973-June 1975 Attending Physician, Clinical Center, National Institutes of Health: July 1973-June 1975 Visiting Lecturer, Department of Medicine, George Washington University Medical Center: November 1973-June 1974 Assistant Clinical Professor of Medicine, George Washington University School of Medicine and Health Sciences: June 1974-June 1975 Assistant Professor of Medicine, Duke University School of Medicine: September 1975-October 1976 Associate Professor of Medicine, University of Miami School of Medicine: November 1976-May 1985 Associate Professor of Pediatrics, University of Miami School of Medicine: November 1976-May 1986 Professor of Medicine, University of Miami School of Medicine: June 1985-Present Professor of Pediatrics, University of Miami School of Medicine: June 1986-Present Professor of Psychology, University of Miami College of Arts and Sciences: October 1986-Present Professor, Graduate School, University of Miami: February 1996-Present Adjunct Professor of Pediatrics, Barbara Davis Center for Childhood Diabetes, University of Colorado at Denver: July 2009-Present Administrative Appointments Medical Director, Physician's Associate Program, Duke University: July 1972-June 1973 Director, Diabetes and Nutrition Clinics and Education Program, Division of Endocrinology and Metabolism, Department of Medicine, Duke University: July 1975-October 1976 Associate Director, Diabetes Research Institute, University of Miami School of Medicine: November 1976November 1986 Director, Diabetes/Metabolic Unit, Division of Endocrinology and Metabolism, Department of Medicine, University of Miami School of Medicine: January 1977-November 1986 Jay S. Skyler Page 3 Curriculum Vitae Project Director, University of Miami/Southeastern Florida Regional Diabetes Program: September 1979-November 1986 Co-Director, NHLBI Behavioral Medicine Research Center, University of Miami: July 1986-June 2009 Chief, Section of Behavioral Internal Medicine, Division of Endocrinology, University of Miami School of Medicine: July 1987-March 2000 Director, Operations Coordinating Center, and Study Chairman, NIDDK Diabetes Prevention Trial for Type 1 Diabetes (DPT-1): August 1993-August 2001 Chairman, NIDDK Diabetes Prevention Trial for Type 1 Diabetes (DPT-1): August 1993-August 2001 Chairman, NIDDK Type 1 Diabetes TrialNet Study Group: August 2001-June 2015 Director, Division of Endocrinology, Diabetes, & Metabolism, Department of Medicine, University of Miami School of Medicine: July 2000-August 2004 Program Director, General Clinical Research Center, University of Miami: August 2000-March 2006 Associate Director for Academic Programs, Diabetes Research Institute, University of Miami School of Medicine: April 2001-June 2011 Area Leader, Immunomodulation & Tolerance, Diabetes Research Institute, University of Miami School of Medicine: March 2008-June 2011 Deputy Director for Clinical Research and Academic Programs, Diabetes Research Institute, University of Miami School of Medicine: June 2011-Present Hospital Appointments Attending Physician, Clinical Center, National Institutes of Health: July 1973-June 1975 Attending Physician, Duke University Medical Center: July 1975-October 1976 Consulting Physician, Durham Veterans Administration Medical Center: July 1975-October 1976 Attending Physician, University of Miami/Jackson Memorial Medical Center: November 1976 - Present Attending Physician, University of Miami Hospital and Clinics/Sylvester Cancer Center: November 1976 - Present Consulting Physician, Miami Veterans Affairs Medical Center: November 1976 - Present Consulting Physician, Mount Sinai Medical Center of Miami Beach: August 1983-July 2001 Attending Physician, University of Miami Hospital: March 2008-Present Military Service Assistant Surgeon (Reserve Corps), United States Public Health Service: October 1969-June 1973; July 1975-June 1980 Surgeon, United States Public Health Service: July 1973-June 1975 6. GRANTS RECEIVED Active “Mesenchymal Precursor Cell Therapy in Type 2 Diabetes” (JS Skyler, PI). Mesoblast, Ltd. Project Period – 6/13/12-6/12/16. “Prospective, Multicenter, Open-Label, First-in-Human Phase 1/2 Study with Two Cohorts to Evaluate the Safety, Tolerability, and Efficacy of Various Doses of VC-01TM Combination Product in Subjects with Type 1 Diabetes Mellitus” (JS Skyler, PI). Viacyte Inc. Project Period – 10/1/15-12/31/17 Major Previous Grant Support “Type 1 Diabetes TrialNet Chairman’s Office” (JS Skyler, PI). NIDDK, NIH. U01. Project Period – 9/1/01 – 6/30/15 “Diabetes Prevention Trial for Type 1 Diabetes (DPT-1)” (Operations Coordinating Center for Multi-Center National Clinical Trial) (JS Skyler, PI). NIDDK, NIH. U01. Project Period - 9/1/93-8/31/03. “General Clinical Research Center” (John Clarkson, P.I.; Jay S. Skyler, Program Director). NCRR, NIH. M01. Project Period – 7/1/02 – 3/31/06 Jay S. Skyler Page 4 Curriculum Vitae “Diabetes Mellitus: Pathogenesis and Immune Intervention” (JS Skyler, PI). NIDDK, NIH. R01. Project Period 9/20/85-8/31/89. “Clinical Islet Transplantation Center” (C Ricordi, PI; JS Skyler, Co-Investigator). NIDDK, NIH. U01. Project Period – 9/30/04-9/29/09 “Biobehavioral Bases of Coronary Heart Disease Risk and Management” (N Schneiderman, PI; JS Skyler, Co-PI & Core Leader). NHLBI, NIH. P01. Project Period 7/1/96-6/30/01. [Continuation of Program Project “Psychophysiology of Cardiovascular Reactivity”] (Program Project Grant), (N Schneiderman, PI; JS Skyler, CoPI). NHLBI, NIH. Project Period 7/1/86-6/30/96. Subprojects: “Diabetes: Reactivity, Stress, Glycemia, & Blood Pressure” (JS Skyler, Project Leader) 7/1/86-6/30/91. “Insulin Sensitivity, Blood Pressure, and Glucose Tolerance” (JS Skyler, Project Leader) 7/1/91-6/30/96. Co-Investigator, 7/1/97-7/31/12. “Biobehavior, Ethnicity, Hormones, & Blood Pressure” (RJ Prineas, PI; JS Skyler, Investigator). NHLBI, NIH. R01. Project Period 12/1/90-11/30/95 “Stress and Immune Function in Control and Complications of Diabetes” (MW Linn, PI; JS Skyler, Co-PI). NIMH. R01. Project Period - 7/1/80-6/30/85. “Dynamic Autonomic Assessment in Diabetic Neuropathy” (BE Hurwitz, PI; JS Skyler, Co-PI). NHLBI, NIH. R01. Project Period 9/1/95-8/31/99. “Diabetes, Metabolism, and Endocrinology Training Grant” (DH Mintz, PI; JS Skyler, Co-PI). NIADDK, NIH. T32. Project Period - 9/01/79-6/30/87. “Behavioral Medicine Research in Cardiovascular Disease Training Grant” (N Schneiderman, PI; JS Skyler, Investigator). NHLBI, NIH. T32. Project Period 7/1/84-5/31/09. “Drug abuse, HIV, Selenium Supplementation, & Cardiovascular Disease Risk” (B Hurwitz, PI; JS Skyler, CoInvestigator). NIDA. R01. Project Period - 7/01/00-6/30/06 “HAART, & Cardiovascular Disease Risk” (B Hurwitz, PI; JS Skyler, Co-Investigator). NIDA. R01. Project Period - 7/01/00 to 6/30/06 “University of Miami Diabetes Education, Treatment and Research Center” (JS Skyler, PI). Florida Department of Health and Rehabilitative Services. Project Period - 9/1/79-6/30/87. “Southeastern Florida Regional Diabetes Program for Children and Youth” (JS Skyler, PI). Florida Department of Health and Rehabilitative Services. Project Period 7/1/77-6/30/87. “Pharmacokinetics of Peritoneal Insulin and Implantable Insulin Delivery Systems” (JS Skyler, PI). Cordis Research Corporation. Project Period 1/1/82-6/30/84. “Tolrestat Use in Diabetic Neuropathy” (JS Skyler, PI). Ayerst Laboratories. Project Period 4/1/83-12/31/85. “Pharmacokinetics of Long-Acting Insulin” (JS Skyler, PI). Lilly Research Laboratories and Novo Research Institute. Project Period - 9/1/83-12/31/85. “Insulin in Type II Diabetes” (JS Skyler, PI). Lilly Research Laboratories. Project Period - 1/1/84-2/28/87. “Cyclosporine in Type I Diabetes - A Controlled Clinical Trial” (JS Skyler, PI). Sandoz Research Institute. Project Period 2/1/84-7/31/87. “Studies of Captopril in Diabetic Patients with Proteinuria or Microalbuminuria” (JS Skyler, PI). Squibb Institute for Research. Project Period - 11/01/87-12/30/90. “Immune Intervention in Type I Diabetes with XomaZyme-H65” (JS Skyler, PI). Xoma Corporation. Project Period - 4/01/89-6/30/90. Jay S. Skyler Page 5 Curriculum Vitae “Studies with a New Insulin Sensitizer in Type II Diabetes Mellitus” (JS Skyler, PI). Boehringer Mannheim Pharmaceuticals. Project Period - 9/01/89-12/30/90. “Dose Timing Study of CI-991, An Insulin Sensitizer” (JS Skyler, PI). Parke-Davis Pharmaceutical Research. Project Period - 1/01/92-05/31/92. “Human Insulin Analog: Premeal Therapy in Type I Diabetes” (JS Skyler, PI). Eli Lilly & Company. Project Period - 1/01/93-12/31/93. “Acetyl-L-Carnitine in Diabetic Peripheral Neuropathy” (JS Skyler, PI). Hoffman-LaRoche. Project Period 10/1/93-3/31/96. “Effects of BTS 67 582 in Patients with Type II Diabetes Uncontrolled on Diet Therapy” (JB Marks, PI; JS Skyler, Co-PI). Boots Pharmaceuticals. Project Period - 10/1/94-9/30/96. “Effects of Tolrestat on Peripheral Nerve Morphology and Biochemistry in Patients with Diabetic Peripheral Neuropathy” (JS Skyler, PI). Wyeth-Ayerst Clinical Research. Project Period - 6/1/91-12/31/96. “The Effects of Inhaled Insulin in Patients with Diabetes Mellitus” (JS Skyler, PI; JB Marks, Co-PI). Pfizer Central Research. Project Period - 10/1/96-12/31/08. “Viaject Insulin in Type 1 and Type 2 Diabetes Mellitus” (JS Skyler, PI; JB Marks & C Hernandez-Cassis, Co-PIs). Biodel, Inc. Project Period – 5/1/07-6/30/08. “Prandial Insulin-PH20 NP Compared to Insulin Lispro in Type 1 Diabetes” (JS Skyler, PI). Halozyme Therapeutics, Inc. Project Period - 7/1/09-6/30/10. “Prandial Insulin-PH20 Type 1 and Type 2 Diabetes” (JS Skyler, PI). Halozyme Therapeutics, Inc. Project Period - 7/1/10-6/25/14. “BHT-3021 in Type 1 Diabetes Mellitus” (JS Skyler, PI; JB Marks, Co-PI). Bayhill Therapeutics, Inc. Project Period – 7/1/07-12/30/10. “Mesenchymal Human Stem Cells in Type 1 Diabetes Mellitus” (JS Skyler, PI). Osiris Therapeutics, Inc. Project Period – 7/1/08-12/30/10. “Assessment of All in One Blood Glucose Device – Pogo” (JS Skyler, PI). Intuity Medical. Project Period - 7/1/106/30/11. “The Effects of Recombinant Human IGF-1 (rhIGF-1) in Patients with Diabetes Mellitus” (JS Skyler, PI; JB Marks, Co-PI). Genentech, Inc. Project Period - 10/1/96-9/30/97. “Studies with Doxazosin and Insulin Resistance” (JS Skyler, PI). Roerig Division, Pfizer Pharmaceuticals. Project Period - 4/1/92-7/31/98. “Aminoguanidine in Diabetic Nephropathy” (JS Skyler, PI). Marion Merrell Dow and Alteon Corporation. Project Period - 10/1/93-12/31/98. “Effects of Zopolrestat in Patients with Diabetic Peripheral Neuropathy” (JS Skyler, PI). Pfizer Central Research. Project Period - 3/1/96-10/31/99. “Effects of Repaglinide on First Phase Insulin Secretion” (JS Skyler, PI). Novo-Nordisk Pharmaceuticals. Project Period - 9/1/98-12/31/99. “Effects of Insulin Aspart in Continuous Subcutaneous Insulin Infusion in Types 1 & 2 Diabetes” (JS Skyler, PI; JB Marks, Co-PI). Novo-Nordisk Pharmaceuticals. Project Period - 3/1/99-3/31/00. Jay S. Skyler Page 6 Curriculum Vitae “The Effects of Trans-Dermal Insulin in Human Subjects” (JS Skyler, PI; JB Marks, Co-PI). Vector Medical. Project Period - 11/1/99-12/31/00. “Protein Kinase C Inhibitor – Studies in Diabetic Retinopathy & Diabetic Macular Edema” (WE Smiddy, PI; JS Skyler, Co-PI). Lilly Research Laboratories. Project Period - 5/1/98-9/30/02. 7. DEPARTMENTAL ADMINISTRATIVE AND COMMITTEE RESPONSIBILITIES Director, Diabetes/Metabolic Unit, University of Miami Hospital & Clinics: 1977-1986 Chief, Endocrinology & Metabolism Section, Department of Medicine, Jackson Memorial Hospital: 1979-1981 Director, Division of Endocrinology Diabetes & Metabolism: 2000-2004 Finance Committee: 1979-1981 Patient Care Committee: 1979-1980 Internship Selection Committee: 1979-1981 Committee on Clinical Competence: 1980-1982, 1985-1986 Department of Medicine Promotions & Tenure Advisory Committee: 2002-2004 Research Task Force: 2004-2005 8. EXTRA-DEPARTMENTAL APPOINTMENTS & RESPONSIBILITIES University of Miami School of Medicine Sophomore Promotions Committee: 1977-1981 Mechanisms of Disease Coordinator Committee: 1977-1981, 1988-1989 Governance Committee, Professional Income Plan: 1977-1979 Governing Board, Professional Income Plan: 1979-1981 Committee for Honors Program in Medical Education (B.S.-M.D.): 1985-1988 Ad Hoc Committee on Faculty Consulting Policy: 1987 General Clinical Research Center (GCRC) Advisory Committee: Member: 1990-1996; Chairman: 1995-1996 Chairman, GCRC Protocol Review Subcommittee: 1990-1994 Chairman, Faculty Council Committee on Mission of the School of Medicine: 1993 Member, Biotechnology Development Committee: 1993 Member, Clinical Research Advancement Group: 1997-1998 Member, Curriculum Revision Subcommittee on Endocrinology & Reproduction: 1999-2001 Program Director, General Clinical Research Center: 2000-2006 Member, Committee on Clinical Research Development & Health Outcomes: 2000-2001 Member, Search Committee for Chair, Department of Pediatrics: 2001-2003 Member, Faculty Council Research Task Force: 2001-2002 Chairman, Search Committee for Chief of Medical Services at Miami Veterans Affairs Medical Service and Vice-Chairman, Department of Medicine: 2002-2003 Chairman, Search Committee for Director, Center for Research Design & Clinical Outcomes: 2003-2004 Center Director, Federation of Clinical Immunology Societies Center of Excellence at the University of Miami: 2004-2007 Chairman, Clinical Research Institute Operations Planning Committee: 2004-2006 Member, Executive Research Council: 2004-2006 Member, Search Committee for Chief, Division of Cardiology: 2005-2006 Chairman, Lawrence M. Fishman Endocrinology Visiting Professorship Committee: 2004-2010 Member, Center on Aging Assessment Committee: 2008 Member, Interdisciplinary Stem Cell Institute, University of Miami: 2012-Present Jackson Memorial Hospital Clinical Nutrition Committee: 1977-1979 Chairman, Diabetes Care Committee: 1979-1982 Diabetic Ketoacidosis Audit Committee: 1979 Chief, Endocrinology Diabetes & Metabolism: 2000-2004 Jay S. Skyler Page 7 Curriculum Vitae University of Miami Hospitals and Clinics Fire and Safety Committee: 1979-1981 Executive Committee, Medical Staff: 1979-1981 Pharmacy & Therapeutics Committee: 1986-2002 Vice-Chairman: 1988-2002 University of Miami Diabetes Research Institute Associate Director: November 1976-November 1986 Investigator: June 2000-Present Associate Director for Academic Programs: April 2001-June 2011 Area Leader, Immunomodulation & Tolerance: 2008-June 2011 Deputy Director for Clinical Research & Academic Programs: June 2011-Present University of Miami Lowe Art Museum Advisory Committee: 1980-1982 Member, Patent and Copyright Committee: 2013-2015 University of Miami/Miami Veterans Administration Medical Center Consultant Physician: 1977-Present Geriatric Research, Education, & Clinical Center Affiliate Member: 1992-Present Clinical Protocol Development Committee: 1992-2000 9. HONORS AND AWARDS, CONSULTANTSHIPS, LECTURES, ETC. a. HONORS AND AWARDS Philadelphia Board of Education Scholarship: 1964-1968 Phi Delta Epsilon Student Scholarship Award Jefferson Medical College: 1968 Hobart Amory Hare Honorary Medical Society Jefferson Medical College: 1967-1969 President: 1968-1969 Solomon Solis-Cohen Memorial Prize for Excellence in Clinical Medicine Jefferson Medical College: 1969 Lowell Ashton Erf Prize for Seriousness of Purpose, Aptitude, and Ability in Medicine Jefferson Medical College: Honorable Mention: 1969 Honorary Physician's Associate - In Recognition of Distinguished Teaching Duke University Medical Center: 1973 Award of Special Distinction for Outstanding Dedication, Personal Commitment and Personal Service American Diabetes Association, Florida Affiliate: 1979 Invited Lecturer International Diabetes Federation Eighth Congress, Vienna, Austria: 1979 Resolution of Gratitude for the Creation of DIABETES CARE Board of Directors, American Diabetes Association: 1982 Invited Lecturer International Diabetes Federation Ninth Congress, Nairobi, Kenya: 1982 Honorary Life Member South African Society for Endocrinology, Metabolism and Diabetes: 1982 Fellow - All India Institute of Diabetes: 1983 Achievement Award “for Distinguished Contributions to the Knowledge of Diabetes Mellitus” American Society of Contemporary Medicine & Surgery: 1985 First “Leon Mow Visiting Professor”, Lions International Diabetes Institute & Monash University, Melbourne, Australia: July 1986 Plenary Lecturer & Medal Recipient International Diabetes Federation Thirteenth Congress, Sydney, Australia: 1988 Twentieth Reunion Lecturer Jefferson Medical College: 1989 Jay S. Skyler Page 8 Curriculum Vitae Celal Oker Memorial Lecturer Turkish Diabetes Association, Istanbul, Turkey: 1991 Swedish Diabetes Foundation Honorary Lecturer Swedish Medical Association, Stockholm, Sweden: 1991 Banting Medal for Service American Diabetes Association: 1992 Novo-Nordisk Lecturer Australian Diabetes Society: 1992 Plenary Lecturer Asociacion Latinoamericana de Diabetes: 1992 (Mar del Plata, Argentina), 1998 (Cartegena, Columbia), 2001 (Punta de este, Uruguay), 2010 (Santiago, Chile), 2013 (Cancun, Mexico) Commencement Speaker Physicians Assistant Program, University of Oklahoma: 1994 Plenary Lecturer & Plaque Recipient International Diabetes Federation Fifteenth Congress, Kobe, Japan: 1994 Honorary Plenary Lecturer Norwegian Diabetes Association: 1995 Best Doctors in America - First Edition 1992-1993; Second Edition 1994-1995; Continuously through 2015 Meritorious Research Award American Diabetes Association - Florida Affiliate: 1996 Invited Lecturer International Diabetes Federation Fourteenth Congress, Helsinki, Finland: 1997 Invited Lecturer Israel Diabetes Association, Tel Aviv: 1998 Glassman Memorial Lecturer Hadassah Medical Center, Hebrew University, Jerusalem, Israel: 1998 First Annual Dean’s Senior Clinical Research Award University of Miami School of Medicine: 1999 Invited Lecturer German Diabetes Association, Munich: 2000 Invited Lecturer Canadian Diabetes Association, Halifax, Nova Scotia: 2000 Invited Lecturer International Diabetes Federation Fifteenth Congress, Mexico City: 2000 America’s Top Doctors - Listed 2001, 2002, 2003, 2004, 2005, 2006, 2007, 2008, 2009, 2010, 2011, 2012, 2013, 2014, 2015 Eric Reiss Memorial Lecturer University of Miami School of Medicine: 2003 Provost’s Award for Scholarly Activity University of Miami: 2003 Simon Gratz Prize for Jefferson Medical College Alumni in recognition of “outstanding contributions to medical research having real practical value to the care of patients” Jefferson Medical College: 2003 Invited Lecturer International Diabetes Federation Sixteenth Congress, Paris: 2003 Julio Santiago Memorial Lecturer Washington University of St. Louis: 2003 Invited Lecturer Turkish Diabetes Association – 40th National Congress, Antalya, Turkey: 2004 Marvin Levin Visiting Professor/Lecturer Washington University of St. Louis: 2004 Master of the American College of Physicians (MACP): 2005 Invited Lecturer, Diabetes India, Jaipur, India: 2005 David Rabin Memorial Lecturer Vanderbilt University: 2005 Eric Reiss Memorial Lecturer University of Miami School of Medicine: 2006 Eastern-Atlantic Student Research Forum Awards Banquet Speaker: 2006 Jay S. Skyler Page 9 Curriculum Vitae Invited Lecturer Opening of Clinical Research Center at Malmo, Lund University, Sweden: 2006 Invited Lecturer International Diabetes Federation 17th Congress, Cape Town, South Africa: 2006 Who's Who in Science and Medicine: 2007-Present Hall of Fame, Physician Assistant Program Duke University Medical Center: 2008 Keynote Lecturer American Association of Diabetes Educators, Atlanta, Georgia: 2009 Establishment of the Jay S. Skyler Visiting Professorship in Diabetes University of Miami Miller School of Medicine: 2009 John Ensinck Visiting Professor University of Washington, Seattle: October 2010 Donnell D. Etzwiler Memorial Lecturer International Diabetes Center, Minneapolis: April 2013 Invited Speaker Joslin Diabetes Center/Harvard Medical School Symposium – Challenges and Opportunities in Type 1 Diabetes Research: May 2013 Invited Lecturer International Diabetes Federation 20th Congress, Melbourne, Australia: 2013 First George Eisenbarth Memorial Lecturer Immunology of Diabetes Society, Lorne, Australia: December 2013 2014 Distinction in Endocrinology Award American College of Endocrinology: May 2014 Mildred “Barrie” Friedman Memorial Lecturer State University of New York Downstate Medical Center: April 2015 2015 Distinguished Faculty Scholar Award Faculty Senate, University of Miami: April 2015 2015 JDRF Mary Tyler Moore and S. Robert Levine Excellence in Clinical Research Award Juvenile Diabetes Research Foundation, New York: September 2015 Brownlee Lectureship Harvard Medical School Longwood Campus/Joslin Diabetes Center: December 2015 b. EXAMINING BOARD MEMBERSHIPS American Board of Internal Medicine Subspecialty Board on Endocrinology and Metabolism Member: 1985-1991 Chairman, Subcommittee on Assessment of Competency in Diabetes: 1987-1988 Subspecialty Board on Endocrinology Diabetes and Metabolism Chairman, Committee on Re-certification (Self Evaluation Process): 1992-1995 c. SOCIETY MEMBERSHIPS AND OFFICES Academy of Behavioral Medicine Research (Fellow) American Association of Clinical Endocrinologists (AACE) American College of Clinical Pharmacology (Fellow) American College of Physicians (Master) Delegate, Council on Subspecialty Societies: 1993-1999 Chair, Council on Subspecialty Societies: 1996-1999 Member, Board of Regents: 1996-1999 Chair, Research Center Advisory Committee: 1997-1999 Member, Subspecialist/Generalist Interface Oversight Group: 1997-1999 Master of the American College of Physicians (MACP): 2005 American Diabetes Association Board of Directors: 1978-1984, 1989-1993 Executive Committee: 1989-1992 Jay S. Skyler Page 10 Curriculum Vitae Vice President: 1989-1990 President-Elect: 1990-1991 President: 1991-1992 American Federation of Medical Research (formerly American Federation of Clinical Research) American Society of Hypertension Association of Subspecialty Professors British Diabetic Association / Diabetes UK Council of Biology Editors / Council of Science Editors Endocrine Society European Association for the Study of Diabetes Federation of American Societies for Experimental Biology Federation of Clinical Immunology Societies (FOCiS) Council, Centers of Excellence: 2003-2006 Immune Tolerance Network Special Member, Network Steering Committee: 2002-2008 Member, Network Steering Committee: 2008-2014 Immunology of Diabetes Society Councilor: 1999-2001 International Diabetes Federation Member 1977 Life Member 1990 Special Consultant to the President: 1982 Organizing Committee, 14th Congress (June 1991) Governing Council: 1989-2000 Executive Board: 1991-2000 Financial Planning Task Force: 1992-1993 Vice-President: 1994-2000 International Diabetes Immunotherapy Group Executive Committee: 1986-1990, 1993-2001 President-Elect: 1996-1999 President: 1999-2001 International Society of Pediatric & Adolescent Diabetes (formerly International Study Group for Diabetes in Children & Adolescents) New York Academy of Sciences Society of Behavioral Medicine (Fellow) Society of Clinical Trials Society of the Sigma Xi Southern Society for Clinical Investigation Councilor: 1989-1994 Chairman, Publications Committee: 1990-1992 President-Elect: 1991-1992 President: 1992-1993 d. EDITORIAL RESPONSIBILITIES DIABETES CARE (A Publication of the American Diabetes Association) Founding Editor-in-Chief: 1977-1982 Advisory Editor: 1983-1987 Associate Editor, DIABETES CARE REVIEWS: 1990-1992 Associate Editor for Reviews: 1999-2001 AMERICAN JOURNAL OF MEDICAL SCIENCES Editorial Board: 1990-2002 AMERICAN JOURNAL OF MEDICINE Board of Consulting Editors: 1981-1986 CANADIAN JOURNAL OF DIABETES CARE Editorial Board: 1994-1997 Jay S. Skyler Page 11 Curriculum Vitae CLINICAL DIABETES (A Publication of the American Diabetes Association) Editorial Board: 1983-1986 CURRENT DIABETES REPORTS Editorial Board: 2012-Present DIABETES METABOLISM REVIEWS Board of Consulting Editors: 1984-1998 DIABETES METABOLISM RESEARCH & REVIEWS (Successor to Diabetes Metabolism Reviews) Board of Consulting Editors: 1999-Present DIABETES, NUTRITION, & METABOLISM: CLINICAL & EXPERIMENTAL Associate Editor: 1987-1993 Editorial Board: 1987-2004 DIABETES, OBESITY AND METABOLISM Editorial Board: 1998-Present DIABETES RESEARCH AND CLINICAL PRACTICE (Journal of the International Diabetes Federation) Editorial Board: 1993-2014 Regional Editor, Western Hemisphere: 1996-2005 DIABETES REVIEWS (A Publication of the American Diabetes Association) Associate Editor: 1993-1997 Editor: 1998-1999 DIABETES SPECTRUM (A Publication of the American Diabetes Association) Editorial Board: 1987-1990 DIABETES TECHNOLOGY & THERAPEUTICS Associate Editor: 2006-2009 Senior Editor: 2009-Present DIABETES & METABOLIC SYNDROME: CLINICAL RESEARCH & REVIEWS Associate Editor: 2005-2014 DIABETIC MEDICINE (Journal of the British Diabetic Association) Editorial Board: 1990-2007 DIABETOLOGIA (Journal of the European Association for the Study of Diabetes) Advisory Board: 2005-2010 EXCERPTA MEDICA/CORE JOURNALS IN CLINICAL ENDOCRINOLOGY Editorial Advisory Committee: 1982-1987 EXPERT REVIEW OF ENDOCRINOLOGY & METABOLISM Editorial Board: 2006-2010 INTERNATIONAL DIABETES FEDERATION BULLETIN Editorial Board: 1983-1985 INTERNATIONAL DIABETES MONITOR Scientific Editor: 1989-2010 JOURNAL OF DIABETES Editorial Board: 2008-Present JOURNAL OF DIABETES AND ITS COMPLICATIONS Editorial Board: 1991-2011 JOURNAL OF DIABETES INVESTIGATION Editorial Board: 2009-2013 JOURNAL OF DIABETES SCIENCE AND TECHNOLOGY Editorial Board: 2007-2012 JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM Editorial Board: 2003-2006 PRACTICAL CARDIOLOGY Editorial Board: 1981-1985 PSYCHOSOMATIC MEDICINE Editorial Board: 2002-2005 THE ENDOCRINOLOGIST Editorial Board: 1997-1999 Reviewer for the Following Journals (*Reviewer During Past Year): Advances in Therapeutics American Journal of Epidemiology Jay S. Skyler Page 12 American Journal of Medical Sciences American Journal of Medicine American Journal of Obstetrics & Gynecology American Journal of Transplantation American Psychologist Analytical Biochemistry Annals of Internal Medicine Archives of Internal Medicine Autoimmunity British Medical Bulletin British Medical Journal Canadian Medical Association Journal Circulation Circulation Research Clinical Endocrinology Clinical Immunology Clinical Therapeutics Diabete et Metabolisme Diabetes* Diabetes Care* Diabetes Educator Diabetes Metabolism Research and Review Diabetes, Nutrition, & Metabolism: Clinical & Experimental Diabetes Research Diabetes Research and Clinical Practice Diabetes Technology & Therapeutics* Diabetic Medicine Diabetologia Endocrine Practice Endocrine Research Communications Endocrinology European Journal of Immunology Expert Review of Endocrinology and Metabolism Health Affairs Health Psychology International Journal of Behavioral Medicine Islet JAMA* Journal of Autoimmunity Journal of Biochemical and Biophysical Methods Journal of Biological Chemistry Journal of Diabetes & Its Complications Journal of Chronic Diseases Journal of Clinical Endocrinology and Metabolism Journal of Clinical Investigation* Journal of Internal Medicine Journal of Laboratory and Clinical Medicine Journal of Pediatrics Journal of Pharmacology & Experimental Therapeutics Journal of the Florida Medical Association Journal of Transplantation Lancet Lancet Diabetes Endocrinology Life Sciences Metabolism Nature Biotechnology Nature Clinical Practice Endocrinology & Metabolism Nature Reviews Drug Discovery Curriculum Vitae Jay S. Skyler Page 13 New England Journal of Medicine* Nutrition Metabolism & Cardiovascular Disease Pediatrics Pediatric Diabetes* PLoS ONE Proceedings of the National Academy of Sciences USA* Proceedings of Society of Experimental Biology & Medicine Psychophysiology Psychosomatic Medicine Science Science Translational Medicine Stem Cells* The Physician and Sports Medicine Curriculum Vitae e. STUDY SECTION AND COUNCIL MEMBERSHIPS National Commission on Diabetes, 1975-1976 Consultant, Committee on Education and Treatment Chairman, Workgroup on Current Status & Future Directions of Therapy State of Florida Governor's Diabetes Advisory Council: 1979-1990, 1994-2002 Joint Food and Drug Administration/United States Pharmacopeia International Workshop on Drugs and Reference Standards for Insulins, Somatotropins and Thyroid Axis Drugs Chairman, Consensus Panel on Insulin, May 1982 National Institute of Arthritis, Diabetes, Digestive and Kidney Diseases Diabetes Control and Complications Trial Policy Advisory Group: 1982-1986, 1993 National Diabetes Information Clearinghouse Advisory Board: 1983-1986 National Institute of Diabetes, Digestive and Kidney Diseases Long Term Planning Panel Member: 2000, 2002 Special Review Committee for Type 2 Diabetes Mellitus Studies in Children Chairman: 2002 Diabetes Strategic Plan – Clinical Research and Trials Sub-Group Member: 2009 Special Review Committee Member: 2009 National Institute of Child Health and Human Development Special Review Panel, Genetic Linkage Analysis of Juvenile Diabetes Mellitus Member: 1978 Chairman: 1979, 1980 Special Review Panel, Primary Prevention of Type I Diabetes Chairman: 1995 National Institutes of Health Behavioral Medicine Study Section Ad Hoc Reviewer: 1979, 1986 Metabolism Study Section Ad Hoc Reviewer: 1980, 1981, 1982, 1984 Special Emphasis Research Career Award Program (NHLBI/NIADDK) - Ad Hoc Reviewer: 1982 Epidemiology and Chronic Disease Study Section Ad Hoc Reviewer: 1986 Advisory Committee on Type 1 Diabetes Member: 2000, 2002 Jay S. Skyler Page 14 Curriculum Vitae Advisory Committee for Restructuring NIH Clinical Research Member: 2003 Special Emphasis Panel Member: 2007, 2008, 2009 National Heart Lung and Blood Institute Special Policy Advisory Review Committee – ACCORD Study Member: 2002 National Institute of Mental Health Treatment Development & Assessment Research Review Committee Ad Hoc Reviewer: 1979 National Center for Research Resources General Clinical Research Centers Review Committee Ad Hoc Reviewer: 2000 Canadian Medical Research Council Ad Hoc Reviewer: 1978, 1983, 1984, 1985, 1988, 2000, 2010 Canadian Institutes of Health Research Ad Hoc Reviewer: 2009 Food and Drug Administration Orphan Drug Program - Ad Hoc Reviewer: 1984, 1989 Endocrinologic & Metabolic Drugs Advisory Committee: 1984-1986 Centers for Disease Control Community Health Care Models for Diabetes Prevention & Control Advisory Committee Member: 19901992 World Health Organization Study Group on Prevention of Diabetes Member: 1992 Juvenile Diabetes Research Foundation (JDRF) Data Safety & Monitoring Board, Anti-CD3 European Trials Chairman: 2002-2004 Special Review Panel Member: 2005, 2006, 2008, 2011, 2012, 2013 Clinical Advisory Committee Member: 2012-2013 Review Panel for International Centers for Type 1 Diabetes TrialNet Member: 2014 European Union Program “Natural Immunomodulators as Novel Immunotherapies for Type 1 Diabetes (NAIMIT) External Advisory Board Chairman: 2010-Present United Kingdom Medical Research Council Reviewer: 2010 Research Foundation Flanders Reviewer: 2011, 2012 Diabetes UK Reviewer: 2013-2014 Helmsley Charitable Trust Reviewer: 2015 f. ADVISORY ACTIVITIES Adocia Advisor: 2015 Ajinomoto Pharmaceuticals Advisor: 2004 Alinea Pharmaceuticals Co-Chairman, Scientific Advisory Board: 2005-2008 Altea Therapeutics Jay S. Skyler Page 15 Advisor: 2001-2006 Member, Scientific Advisory Board: 2008-2009 American Academy of Physician's Assistants Advisor for Continuing Education: 1973, 1976, 1977, 1979 Amgen, Inc. Advisor: 2006 Amylin Pharmaceuticals, Inc. Advisor: 1997-2003 Member, Board of Directors: 1999-2012 Andrx Corporation Member, Scientific Advisory Board: 1996-1999 Animas Corporation Member, Advisory Board: 2003-2006 Astra-Zeneca Advisor: 2014-Present AtheroGenics, Inc. Advisor: 2007-2009 Aventis Pharmaceuticals Advisor: 1999-2005 Bayer Corporation Advisor: 1999 Bayer Diabetes Care Advisor: 2008 Bayer/GSK Levitra Advisory Board: 2003 Baxter Healthcare Advisor: 2008 Becton-Dickinson Advisor: 2004, 2009-2012 Berg Health Advisor: 2014 Biodel, Inc. Advisor: 2014 Biogenix Corporation/Exact Science, Inc. Medical Advisor & Member, Board of Directors: 1987-1990 Chairman, Medical Advisory Board: 1988-1990 Biosite, Inc. Advisor: 2005 Boehringer-Ingelheim Pharmaceuticals Inc. Member, President’s Advisory Council: 2013 Advisor: 2014-Present Boehringer-Mannheim Inc. (Corange Group) Member, Global Diabetes Advisory Group: 1995-1998 Boehringer-Mannheim Pharmaceuticals, Inc. Member, Diabetes Policy Advisory Group: 1988-1991 Boston Medical Technologies Member, Scientific Advisory Board: 1999-2002 Bristol Myers Squibb Diabetes Franchise Steering Committee: 1994-2003 Advisor: 1994-2005, 2008, 2013 Bristol Myers Squibb/Astra Zeneca Diabetes Franchise Advisor: 2013 Cebix, Inc. Member, Scientific Advisory Board: 2012 Centocor Advisor: 2001 Chromium Information Bureau Member, Scientific Advisory Board: 1995-2000 CIBC World Markets Curriculum Vitae Jay S. Skyler Page 16 Advisor: 2007 Clinical Products, Ltd. Chairman, Scientific Advisory Board: 1998-2005 CoGenesys, Inc. Advisor: 2007 Converge, Inc. Member, Scientific Advisory Board: 2006-Present CPEX Pharmaceuticals, Inc. Advisor: 2008 CV Therapeutics Advisor: 2008 Daiichi-Sankyo Advisor: 2008, 2010 Dance Biopharm, Inc. Advisor: 2011-2013, 2015-Present Member, Board of Directors: 2013-2015 Debiopharm Advisor: 2003-2004, 2014-2015 Dexcom, Inc. Member, Board of Directors: 2002-Present Diabetes Centers, Inc. External Advisory Board: 1985 Diabetes Support Systems, Inc. Member, Board of Directors: 1995-1998 Diabetes Treatment Centers of America Member, Scientific Advisory Council: 1990-2000 Diabetes Treatment Centers of America Foundation National Medical Advisory Council: 1984-1990 Diabetogen Biosciences Inc. Scientific Advisory Board: 2000-2002 diaDexus, Inc. Diabetes Advisory Board: 2010 Diamedix, Inc. Scientific Advisory Board: 1986-1988 Diasa, Inc. Member, Board of Directors: 1998-2000 DiaVacs, Inc. Scientific Advisory Board: 2013-Present dLife Communications Member, Advisory Board: 2005-2007 Domain Associates, L.L.C. Special Advisor: 2002-2004, 2007-2008 Drexel, Burnham, Lambert Advisor: 1984-1985 Elcelyx Advisor: 2013-Present Eli Lilly & Company Advisor: 1982-1984, 2002, 2007-2008, 2012 Continuing Medical Education Advisory Committee: 1984-2003 Elizabeth Therapeutics Founder; Chairman of the Board: 2014-present Emisphere Technologies, Inc. Member, Medical Advisory Board: 2007 Essentialis, Inc. Advisor: 2011 Exocell, Inc. Member, Medical Advisory Board: 1992 Exsulin, Inc. Scientific Advisor: 2008-2011 Curriculum Vitae Jay S. Skyler Page 17 Curriculum Vitae FABRUS, Inc. Advisor: 2013 Florida Hospital Medical Center, Orlando Chairman, Blue Ribbon Review Committee: 1990 Forest Laboratories Advisor: 2002, 2005 GMP Companies, Inc Member, Medical Advisory Board: 2000-2006 Genentech Advisor: 1994, 2009 General Electric Corporation Advisor, Medical Systems Division: 1971 Gilead Advisor: 2011-Present Glaxo-Wellcome Diabetes Medical Advisory Board: 1999-2000 GlaxoSmithKline Diabetes Medical Advisory Board: 2000-2001 Goldman-Sachs Advisor: 2010, 2012, 2014 Halozyme, Inc. Advisor: 2008, 2013-Present HealthBanc, Inc. Member, Board of Directors: 1998-2003 HealthScreenDirect, LLC. Advisor: 2007-2008 Hoffman-LaRoche Advisor: 1990, 2011 Member, Humanized Anti-TAC Advisory Board: 1993 Home Diagnostics, Inc. Scientific Advisory Board: 1986-1992 Hyperion Therapeutics Advisor: 2014 Ideal Life Advisor: 2006-Present Immunex Advisor: 2001 Institute for Diabetes Discovery Scientific Advisory Board: 1996-2005 Intarcia Scientific Advisory Board: 2013-Present IntraCellular Health, Inc. Member, Medical and Scientific Advisory Board: 1995-1997 International Diabetes Institute, Monash University, Melbourne, Australia Special Advisor: 1992-2000 IVAX Corporation (Previously Pharmedix, Inc.) (including Baker-Norton Pharmaceuticals and Ivax Bioscience) Scientific Advisory Board: 1986-1988 Business Advisory Board: 1992-1993 Chairman, Medical Food Advisory Board: 1996-1997 Advisor: 1998-2000, 2007 Johnson & Johnson Advisor: 2008 Johnson & Johnson/Ortho-McNeil Advisor: 2003-2004 JotMate, Inc. Member, Board of Directors: 2008-Present Kinexum, LLC Advisor: 2003-2004 Jay S. Skyler Page 18 Curriculum Vitae Kos Pharmaceuticals Advisor: 2002-2006 Kyowa Hakko Kirin Co., Ltd. Advisor: 2010 Liberty Medical / Polymedica Advisor: 2006 LifeGate. Inc. Member, Board of Directors: 2007-Present Lipha Pharmaceuticals/Merck KGaA/EMD Pharmaceuticals Metformin Steering Committee: 1987, 1994 Diabetes Scientific Advisory Board: 1997-2005 MannKind Corporation Advisor: 2002-2012 Mars Symbioscience Advisor: 2009-2010 Medco/Merck Diabetes Advisory Committee: 1994 Medingo Ltd. Scientific Advisory Board: 2006-2010 MediSense, Inc. (Abbott) Member, Advisory Panel: 1998 Mega Technologies, Inc. Advisor: 1984-1990 Member, Board of Directors: 1984-1990 Mellitech S.A.S. Advisor: 2011 Merck and Company Advisor: 1997, 2009, 2012, 2015 Merrill, Lynch, Inc. Advisor: 1985, 1996-2002 Mesoblast Limited Advisor: 2013-Present Miles Laboratories, Diagnostics Division Advisor: 1989 Miles Laboratories, Pharmaceuticals Division Advisor: 1991 MiniMed Corporation Chairman, Medical Advisory Board: 1989-2000 Member, Board of Directors: 2000-2001 Moerae Matrix Inc. Member, Board of Directors: 2009-Present Moerae Vascular, LLC/VasoPrep Surgical Member, Board of Directors: 2011-Present Muttart Diabetes Research & Training Center, University of Alberta Member, External Advisory Committee: 1992-2000 National Commission on Diabetes, 1975-1976 Consultant, Committee on Education and Treatment National Heart and Lung Institute (Hypertension-Endocrine Branch) and National Institute of Mental Health Consultant: 1975-1977 Neurocrine Biosciences, Inc Advisor: 2001 Nipro Medical Corporation Advisor: 2004 Novartis Pharmaceuticals Vildagliptin Medical Advisory Board: 2003-2005 Advisor: 2008 Novo Research Institute International Diabetes Research Advisory Group (DRAG): 1985-1993 Jay S. Skyler Page 19 Curriculum Vitae Novo-Nordisk, A/S External Peer Review Group: 1994 Advisor: 2013 Novo-Nordisk, Inc. Senior Advisory Committee: 1997-2008 NPS Pharmaceuticals, Inc. Advisor: 2014 Nutrio Technologies, Inc Scientific Advisory Board: 2002-2005 Nutrition 21 Advisory Board: 2006-2008 Ono Pharmaceuticals Advisor: 2010 Opko Health Advisor: 2013 Orgenesis Scientific Advisory Board: 2013-Present Paean Therapeutics Founder; Chairman of the Board: 2012-present Parke-Davis Pharmaceutical Research Division, Warner-Lambert Company Advisor: 1990-1994 Patton Medical Devices Scientific Advisory Board: 2005-2011 Pennsylvania Diabetes Academy Scientific Advisory Board: 1985 Pfizer Pharmaceuticals Visiting Professorship Program in Diabetes Academic Advisory Committee: 1991-1994 Pfizer Pharmaceuticals Diabetes Advisory Board: 1991-1992, 1998-2008 Member, Zopolrestat Advisory Board: 1993-1998 Member, Inhaled Insulin Advisory Board: 1997-2007 PhaseBio Pharmaceuticals, Inc. Advisor: 2013-Present Philips Home Care Chronic Disease Project Advisor: 2008 Physician's Associate Program, Duke University Advisory Board: 1973-1974 Advisory Consultant: 1973-1976 Precision Medical Devices, Inc. Member, Board of Directors: 1998-2005 Present Diabetes LLC. Member, Scientific Advisory Board: 2006-2008 Regeneron Pharmaceuticals, Inc. Advisor: 2015 REMD Biotherapeutics, Inc. Advisor: 2015 Roche Diagnostics Special Advisor: 2002, 2006 Advisor: 2013 Roche Pharmaceuticals Diabetes Advisory Board: 2006, 2007 Rodman & Renshaw Advisor: 2006-2008 Salutria Pharmaceuticals Advisor: 2009 Sanofi-Synthelabo Metabolism Advisory Board: 2004 Sanofi (Previously sanofi-aventis) Metabolism Advisory Board: 2004-2007 Jay S. Skyler Page 20 Advisor: 2004-Present Chairman, Type 1 Diabetes Advisory Board: 2010-Present Satiogen Advisory Board: 2010 Searle Member, Magnesium Advisory Board: 1993 Sekris Advisory Board: 2012 Servier Advisor: 2009 Smith Kline Beckman Consultant: 1989 Smith Kline Beecham Member, Rosiglitazone Advisory Board: 1998-2001 Smiths Medical / Deltec Insulin Pump Advisory Board: 2003-2006 Squibb-Novo, Inc. Medical Advisory Council: 1984-1986 SynAlpha Therapeutics LLC Founder; Chairman of the Board: 2013-present Takeda Pharmaceuticals Advisor: 2010-2012 Takeda Pharmaceuticals North America Diabetes Advisory Board: 1999-2003 Tethys Bioscience Scientific Advisory Board: 2009 Teva Advisor: 2008-2009 Tolerx, Inc. Scientific Advisory Board: 2008 Transition Therapeutics Scientific Advisory Board: 2003-2006 TransTech Pharma Advisor: 2015 University of Minnesota Program Project: Pancreas Transplantation External Advisory Committee: 1986 Università Campus Bio-Medico di Roma Member, International Advisory Board: 2001-2005 Valeritas LLC Diabetes Advisory Board: 2006-Present VasoPrep Surgical, LLC Member, Board of Directors: 2012-present Veroscience LLC Advisor: 2008 Viacyte (Previously Novocell) Scientific Advisory Board: 2009-Present Virginia Mason Medical Research Foundation Consultant: 1983-1984 vTv Therapeutics (Previously TransTech Therapeutics) Advisor: 2015-Present Warburg Pincus Advisor: 2014 William Warren Medical Research Institute Consultant: 1986 Wyeth-Ayerst, Inc. Tolrestat Commission: 1987-1988 Tolrestat Neuropathy Steering Committee: 1990-1996 Yamanouchi Pharmaceuticals Advisor: 2004 Curriculum Vitae Jay S. Skyler Page 21 ZyCare, Inc. (Previously Health Ware, Inc.) Member, Scientific Advisory Board: 1996-2000 Zylera Pharmaceuticals, Inc. Advisor: 2006 Zymogenetics, Inc. Advisor: 1996 Curriculum Vitae g. VISITING PROFESSORSHIPS (Selected) Portsmouth Naval Regional Medical Center, Portsmouth, Virginia - April 1979 State University of New York, Upstate Medical Center, Syracuse, NY - October 1979 Oakland Naval Regional Medical Center, Oakland, California - October 1979 George Hamwi Memorial Lecturer, Central Ohio Diabetes Association - October 1982 Leon Smelo Memorial Lecturer, American Diabetes Association, Alabama Affiliate - October 1982 Frederick Lind Memorial Lecturer, Bryn Mawr Hospital, Bryn Mawr, PA - October 1984 1984 “Steven Broidy Visiting Professor”, Cedars Sinai Medical Center, UCLA, Los Angeles, CA - March 1984 First “Leon Mow Visiting Professor”, Lions International Diabetes Institute & Monash University, Melbourne, Australia - July 1986 Lennon Lecturer, Huron Road Meridia Hospital, Cleveland, Ohio - April 1988 DeWitt Burnham-Bernard Robson Visiting Professor, Pacific Presbyterian Medical Center, San Francisco, CA December 1988 Fourth Annual Samuel Levit Honorary Lecturer, Hahnemann University, Philadelphia, PA - March 1990 Leon Smelo Memorial Lecturer, Birmingham (Alabama) Society of Internal Medicine - April 1990 First Eli Lilly Visiting Professor, Muttart Diabetes Research and Training Center, University of Alberta, Edmonton - May 1990 Phillip Sarver Visiting Professor, The Hospital of the Good Samaritan & University of Southern California, Los Angeles, CA - October 1990 Barbara Scott Maroney Memorial Lecturer, Interstate Postgraduate Medical Association of North America, Lake Buena Vista, FL – November 1990 Harry McPherson Symposium in Endocrinology, Duke University Medical Center, Durham, NC - November 1993 47th John Herr Musser Lecturer, Musser-Burch Society, Tulane University Medical Center, New Orleans, LA September 1994 Third Harold Rifkin Visiting Professor, Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, NY - April 1995 Tripler Army Medical Center, Honolulu, Hawaii – July 1998 George Hamwi Memorial Lecturer, Central Ohio Diabetes Association - November 1998 Walter Reed Army Medical Center, Washington – May 2002 Marvin Levin Visiting Professor at Washington University – November 2004 Barbara Davis Center for Childhood Diabetes, Denver – October 2005 Duke University Medical Center – October 2005 University of Texas Health Sciences Center, San Antonio – November 2005 David Rabin Visiting Professor, Vanderbilt University – November/December 2005 University of Colorado Keystone Diabetes Course – July 2006 University of Colorado Keystone Diabetes Course – July 2007 Great Plains Diabetes Center, Kansas City – March 2008 University of Colorado Keystone Diabetes Course – July 2008 La Jolla Institute of Allergy and Immunology – March 2009 University of Pittsburgh Medical Center – March 2009 Turney Lecture, Virginia Commonwealth University – April 2009 University of Colorado Keystone Diabetes Course – July 2009 Mayo Medical School, Rochester, Minnesota - September 2009 University of Colorado Keystone Diabetes Course – July 2010 University of Washington, Seattle – October 2010 University of Colorado Keystone Diabetes Course – July 2012 University of Florida, Gainesville – September 2012 Columbia University, New York – November 2012 Jay S. Skyler Page 22 Curriculum Vitae Donnell D. Etzwiler Memorial Lecture, International Diabetes Center, Minneapolis – April 2013 Columbia University, New York – April 2013 Joslin Diabetes Center, Boston – May 2013 University Children's Hospital, Ljubljana, Slovenia – June 2013 University of Colorado Keystone Diabetes Course – July 2013 University of Colorado Keystone Diabetes Course – July 2014 State University of New York Downstate Medical Center, Brooklyn – April 2015 h. SCIENTIFIC PRESENTATIONS: NATIONAL & INTERNATIONAL MEETINGS Beilinson Diabetes Symposium; Natanya, Israel - October 1972 First International Workshop on Diabetes & Camping; Lake Saint Croix, Wisconsin - May 1974 First International Congress on Obesity; London, England - October 1974 American Federation of Clinical Research, Eastern Section; Boston, Massachusetts - January 1975 International Symposium on Growth Hormone & Related Peptides; Milan, Italy - September 1975 ADA National Postgraduate Course, New York - January 1978 Endocrine Society 30th Postgraduate Assembly; Miami Beach, FL - October 1978 Southern Sugar Club; Kiawah Island, SC - April 1979 International Symposium on New Approaches to the Management of the Patient with Diabetes Mellitus; New York, N.Y. - May 1979 NIH Conference on Psychosocial & Behavioral Aspects of Diabetes; Madison, Wisconsin - May 1979 American Dietetic Association; Las Vegas, NV - October 1979 American Diabetes Association Conference on Gestational Diabetes; Chicago, IL - November 1979 ADA National Postgraduate Course, Atlanta, GA - January 1980 University of Nottingham Symposium on Home Blood Glucose Monitoring; Nottingham, England - March 1980 ADA National Postgraduate Course, Phoenix, AZ - January 1981 National Continuing Medical Education Television Network; Live from Cincinnati, Ohio - June 1981 International Study Group on Diabetes in Children and Adolescents; Les Collons, Switzerland, September 1981 International Symposium on Artificial Systems for Insulin Delivery; Assisi, Italy - September 1981 Beilinson Diabetes Symposium; Herzylia, Israel - November 1981 ADA National Postgraduate Course, Orlando, FL - January 1982 Steno Memorial Hospital 50th Anniversary Symposium; Gentofte, Denmark - May 1982 International Symposium on Insulin Delivery; Toronto - June 1982 International Symposium on Human Insulin of Recombinant DNA Origin; San Francisco, CA - June 1982 American Diabetes Association, Annual Meeting; San Francisco, CA - June 1982 International Diabetes Federation Congress; Nairobi, Kenya - November 1982 South African Society for Endocrinology, Metabolism, & Diabetes; Capetown, South Africa - November 1982 ADA National Postgraduate Course, Denver, CO - January 1983 Third Aberdeen Colloquium on Diabetes and Pregnancy; Aberdeen, Scotland - April 1983 Symposium on Intensive Insulin Therapy; Copenhagen, Denmark - April 1983 Second Japan-Korea Diabetes Symposium; Nagoya, Japan - September 1983 American Academy of Family Physicians, Annual Meeting; Miami Beach, FL - October 1983 British Diabetic Association Postgraduate Course; Nottingham, England - January 1984 4th Symposium on Diabetes Mellitus in Asia & Oceania; Melbourne, Australia - January 1984 International Symposium on Diabetes Education; Melbourne, Australia - January 1984 International Symposium on Human Insulin and Diabetes Epidemiology; Hobart, Tasmania - January 1984 International Symposium on Immunology in Diabetes; Rome, Italy - March 1984 ADA “Clinical Education Program” for Type II Diabetes (National Television Faculty) - April 1984 American College of Physicians Annual Meeting; Atlanta, GA - April 1984 2nd International Symposium on Insulin Delivery Devices; Toronto, Canada - June 1984 ADA National Postgraduate Course, New Orleans, LA - January 1985 American Society of Contemporary Medicine & Surgery; Orlando, FL - March 1985 American Academy of Pediatrics; Atlanta, Georgia - April 1985 Endocrine Society 37th Postgraduate Assembly; Bal Harbour, FL - October 1985 American College of Physicians Annual Meeting; San Francisco, CA - April 1986 American Academy of Pediatrics Annual Meeting; Washington, D.C. - November 1986 Jay S. Skyler Page 23 Curriculum Vitae American Diabetes Association Consensus Conference on Blood Glucose Monitoring, Opening Keynote Address; Washington, D.C. - November 1986 National Heart, Lung, and Blood Institute Conference on Research in Cardiovascular Behavioral Medicine; Key Biscayne, FL - December 1986 ADA National Postgraduate Course, Orlando, FL - January 1987 Juvenile Diabetes Foundation Conference on Immune Intervention in Type I Diabetes; Houston, TX - February 1987 American Association of Diabetes Educators, Annual Meeting, Keynote Address; Orlando - September 1987 Interstate Postgraduate Medical Association of North America (72nd Scientific Assembly); Hollywood, FL November 1987 Diabetic Renal-Retinal Symposium #4; New York - November 1987 ADA National Postgraduate Course, Palm Desert, CA - January 1988 4th Aberdeen Colloquium on Diabetes and Pregnancy; Aberdeen, Scotland - April 1988 Immunointervention in Autoimmune Diseases; Paris - June 1988 Cardiostim '88; Monaco - June 1988 Third International Symposium on Treatment of Diabetes Mellitus; Nagoya, Japan - July 1988 Eighth International Congress of Endocrinology; Kyoto, Japan - July 1988 International Diabetes Federation Congress, Plenary Lecture; Sydney, Australia - November 1988 American Academy of Pediatrics; Orlando, Florida - March 1989 Fifth Korea-Japan Diabetes Symposium; Cheju Island, Korea - April 1989 Endocrine Society of Thailand, Bangkok - April 1989 Hong Kong College of General Practicioners, Kowloon - April 1989 Philippine Society of Endocrinology & Metabolism, Manila - April 1989 Cebu Medical Society, Manila, Philippines - April 1989 American Diabetes Association, Annual Meeting; Detroit, Michigan - June 1989 Academy of Behavioral Medicine Research; Lake Mohank, NY - June 1989 American Association of Diabetes Educators, Annual Meeting; Seattle, Washington - August 1989 ADA National Postgraduate Course, Orlando, FL - January 1990 Turkish Diabetes Association, Istanbul, Turkey - March 1990 Tenth International Workshop, Immunology of Diabetes; Jerusalem, Israel - March 1990 American College of Physicians Annual Meeting; Chicago, Illinois - April 1990 NIH Workshop on Clinical Trials of Immunomodulation for Prevention of IDDM - April 1990 Endocrine Society Annual Meeting; Atlanta, Georgia - June 1990 Second International Symposium on Immunotherapy of Type I Diabetes; London, England - September 1990 Interstate Postgraduate Medical Association of North America (75th Scientific Assembly); Orlando, FL November 1990 Mexican Society of Endocrinology and Nutrition 30th Congress; Acapulco, Mexico - November 1990 American Diabetes Association Postgraduate Course, Keynote Address; San Diego, California - January 1991 Associazione Medici Diabetologi 8th National Congress; Giardini Naxos, Touramina, Sicily - April 1991 Turkish Diabetes Association; Istanbul, Turkey - May 1991 International Diabetes Federation Congress; Washington, DC – June 1991 Symposium on Diabetic Neuropathy; Melbourne, Australia - July 1991 American Association of Diabetes Educators, Annual Meeting; Baltimore, Maryland - September 1991 Eleventh International Workshop, Immunology of Diabetes; Nagasaki, Japan - November 1991 Swedish Medical Association; Stockholm, Sweden - November 1991 American Diabetes Association Postgraduate Course; Orlando, Florida - January 1992 American Diabetes Association, Annual Meeting; San Antonio, TX - June 1992 Australian Diabetes Society; Adelaide, South Australia - September 1992 XIV Congreso Chileno de Medicina Interna; Santiago, Chile - October 1992 VIII Congreso de la Asociacion Latinoamericana de Diabetes; Mar del Plata, Argentina - October 1992 Sociedad Venezolana de Endocrinologia y Metabolismo - Simposio Sobre Diabetes Mellitus; Caracas, Venezuela - October 1992 JDF/Joslin Nice Neuropathy Circles Meeting; Nice, France - November 1992 Egyptian Diabetes Care Association/American Diabetes Association Postgraduate Course on Diabetes Mellitus; Giza, Egypt - November 1992 Twelfth International Workshop, Immunology of Diabetes; Orlando, Florida – March 1993 American Academy of Pediatrics; Chicago, Illinois - March 1993 American Association of Clinical Endocrinologists; San Francisco, California - May 1993 Jay S. Skyler Page 24 Curriculum Vitae Endocrine Society Annual Meeting; Las Vegas, Nevada - June 1993 American Diabetes Association, Annual Meeting; Las Vegas, Nevada - June 1993 International Business Communications Conference on Diabetes Mellitus; Miami – January 1994 I Congresso Português de Diabetes, Sociedade Portuguesa de Diabetologia; Porto, Portugal - February 1994 Juvenile Diabetes Foundation Workshop on Islet Specific Antigens; San Francisco, California - March 1994 International Business Communications Conference on Diabetes Mellitus; London, England - April 1994 Eastern Regional Osteopathic Convention; Atlantic City, New Jersey - April 1994 Thirteenth International Workshop, Immunology of Diabetes; Paris, France – 1994 Endocrine Fellows Foundation Annual Meeting; New Orleans, Louisiana - June 1994 American Diabetes Association, Annual Meeting; New Orleans, Louisiana - June 1994 Endocrine Society Annual Meeting; Anaheim, California - June 1994 Third International Congress of Behavioral Medicine; Amsterdam, Netherlands - July 1994 21st Meeting of Brazilian Society of Endocrinology; Curitiba, Brazil - October 1994 Society of Diabetes of Argentina; Buenos Aires, Argenina - October 1994 American Academy of Pediatrics; Dallas, Texas - October 1994 International Diabetes Federation Congress, Plenary Lecture; Kobe, Japan - November 1994 International Symposium on Type I Diabetes Mellitus; Nagasaki, Japan - November 1994 American Psychosomatic Society; New Orleans, Louisiana - March 1995 Paraguay Society of Internal Medicine; Asuncion, Paraguay - May 1995 Norwegian Diabetes Association; Oslo, Norway - May 1995 American Society of Hypertension; New York, NY - May 1995 American Diabetes Association, Annual Meeting; Atlanta, GA - June 1995 International Pancreas and Islet Transplantation Society; Miami Beach, FL - June 1995 ADA Research Symposium on Prediction & Prevention of Type I Diabetes, Estes Park, Colorado - September 1996 Immunology of Diabetes Society; Orvieto, Italy – October 1995 Foundation for Innovation in Medicine; Washington, DC - November 1995 8th Congress of the ASEAN Federation of Endocrine Societies; Manila, Philippines - December 1995 Hong Kong Society of Endocrinology & Metabolism; Hong Kong - December 1995 Steno Memorial Hospital 75th Anniversary of Insulin Symposium; Gentofte, Denmark - May 1996 American Diabetes Association, Annual Meeting; San Francisco, CA - June 1996 International Diabetes Federation Diabetes Declaration of Americas Conference; San Juan, Puerto Rico - August 1996 Foundation for Innovation in Medicine; New York, NY - November 1996 Immunology of Diabetes Society; Canberra, Australia – December 1996 Carribean Diabetes Association; Ocho Rios, Jamaica – March 1997 General Clinical Research Centers Annual Meeting; Crystal City, Virginia - March 1997 American College of Physicians Annual Meeting; Philadelphia, PA - March 1997 American Diabetes Association, Annual Meeting; Boston, MA - June 1997 Endocrine Society Annual Meeting; Minneapolis, Minnesota - June 1997 International Diabetes Federation Congress; Helsinki, Finland – July 1997 International Business Communications Conference on Obesity; Miami – November 1997 Israel Diabetes Association; Tel Aviv – January 1998 American College of Physicians Annual Meeting; San Diego, CA – April 1998 Immunology of Diabetes Society; Oak Brook, Illinois – June 1998 American Diabetes Association, Annual Meeting; Chicago, IL - June 1998 European Association for the Study of Diabetes; Barcelona, Spain – September 1998 Visiting Professor in China; Beijing, Shanghai, Xian – September 1998 X Congreso de la Asociacion Latinoamericana de Diabetes; Cartagena, Colombia – October 1998 American Diabetes Association Postgraduate Course; Orlando, FL - January 1999 American College of Physicians Annual Meeting; New Orleans, LA – April 1999 American Diabetes Association, Annual Meeting; San Diego, CA - June 1999 Endocrine Society Annual Meeting; San Diego, CA – June 1999 EASD Postgraduate Course; Kaunas, Lithuania – September 1999 European Association for the Study of Diabetes; Brussels, Belgium – September 1999 Endocrine Society Postgraduate Assembly; Los Angeles, CA – October 1999 Immunology of Diabetes Society; Fiuggi, Italy – October 1999 American Diabetes Association Postgraduate Course; Honolulu, Hawaii - January 2000 Jay S. Skyler Page 25 Curriculum Vitae Southern Society of Clinical Investigation; New Orleans, LA – February 2000 American College of Physicians Annual Meeting; Philadelphia, PA – April 2000 German Diabetes Association; Munich, Germany – May 2000 American Diabetes Association, Annual Meeting; San Antonio, TX - June 2000 Endocrine Society Annual Meeting; Toronto, Ontario, Canada – June 2000 European Association for the Study of Diabetes; Jerusalem, Israel – September 2000 EASD Postgraduate Course; Jerusalem, Israel – September 2000 Juvenile Diabetes Foundation Workshop on Prevention of Diabetes; Snow Mountain, Colorado – October 2000 Canadian Diabetes Association; Halifax Nova Scotia – October 2000 International Society of Pediatric and Adolescent Diabetes; Los Angeles – November 2000 International Diabetes Federation Congress; Mexico City – November 2000 American Diabetes Association, Annual Meeting; Philadelphia, PA – June 2001 Ashland Endocrine Conference; Ashland, Oregon – August 2001 American Association of Clinical Endocrinologists Consensus Development Conference; Washington, DC – August 2001 European Association for the Study of Diabetes; Glasgow, Scotland – September 2001 XI Congreso de la Asociacion Latinoamericana de Diabetes; Punte de Este, Uruguay – November 2001 American Diabetes Association Postgraduate Course; San Francisco, CA – January 2002 Visiting Professor in China; Beijing, Shanghai, Xiamen, Guangzhou – February-March 2002 American Diabetes Association, Annual Meeting; San Francisco, CA – June 2002 European Association for the Study of Diabetes; Budapest, Hungary – September 2002 Immunology of Diabetes Society; Copper Mountain, Colorado – October 2002 IDF Conference: Type 2 Diabetes in the Adolescent: The Evolving Epidemic; Los Angeles – February 2003 American Chemical Society; New Orleans, LA – March 2003 American Diabetes Association, Annual Meeting; New Orleans, LA – June 2003 International Diabetes Federation Congress; Paris, France – August 2003 Endocrine Society Postgraduate Assembly; Miami Beach, FL – October 2003 New York Academy of Sciences; New York City – October 2003 Immunology of Diabetes Society; Cambridge, UK – March 2004 American Diabetes Association, Annual Meeting; Orlando, FL – June 2004 Juvenile Diabetes Research Foundation – European Association for the Study of Diabetes Workshop; Oxford, UK – August 2004 European Association for the Study of Diabetes; Munich, Germany – September 2004 EASD/ADA/IDF Postgraduate Course; Nairobi Kenya & Yaounde Cameroon – April 2005 Diabetes Technology Society Clinical Meeting; San Francisco – April 2005 American Association of Clinical Endocrinologists; Washington DC – May 2005 Endocrine Society, Annual Meeting ENDO 05; San Diego, CA – June 2005 American Diabetes Association, Annual Meeting; San Diego, CA – June 2005 European Association for the Study of Diabetes; Athens, Greece – September 2005 Diabetes India; Jaipur, India – November 2005 International Symposium on Prevention of Type 1 Diabetes: The New Frontier; Rome, Italy – March 2006 First International Conference on Diabetes Cell Therapy; Tel Aviv, Israel – March 2006 American Association of Clinical Endocrinologists; Chicago – April 2006 Endocrine Society Annual Meeting; Boston - June 2006 European Congress of Immunology; Paris – September 2006 European Association for the Study of Diabetes; Copenhagen – September 2006 Cardiometabolic Health Congress; Boston – October 2006 International Diabetes Federation Congress; Cape Town, South Africa – December 2006 American Diabetes Association Postgraduate Course; New York, NY – February 2007 Amsterdam Diabetes Forum; Amsterdam, Netherlands – March 2007 Endocrine Society, Annual Meeting ENDO 07; Toronto, Ontario – June 2007 American Diabetes Association, Annual Meeting; Chicago – June 2007 European Association for the Study of Diabetes; Amsterdam – September 2007 Cardiometabolic Health Congress; Boston – September 2007 Aspen Institute Health Forum; Aspen, Colorado – October 2007 Immunology of Diabetes Society; Miami Beach – November 2007 International Diabetes Summit; Columbus, Ohio – November 2007 American Diabetes Association Postgraduate Course; San Francisco – January/February 2008 Jay S. Skyler Page 26 Curriculum Vitae American College of Physicians Annual Meeting; Washington DC – April 2008 American Association of Clinical Endocrinologists; Orlando – April 2008 American Diabetes Association, Annual Meeting; San Francisco – June 2008 American Association of Diabetes Educators Annual Meeting; Washington DC – August 2008 Cardiometabolic Health Congress; Boston – October 2008 EASD/ADA/IDF Postgraduate Course; Hanoi, Viet Nam – November 2008 University of Miami Global Business Forum; Coral Gables, FL – January 2009 Clinical Diabetes & Endocrinology in 2009; Snowmass, CO – January 2009 American Diabetes Association Postgraduate Course; New York, NY – February 2009 PriMed; Fort Lauderdale, FL – February 2009 International Conference on Advanced Technologies and Treatments for Diabetes; Athens Greece – February 2009 American Diabetes Association, Annual Meeting; New Orleans – June 2009 Endocrine Society, Annual Meeting ENDO 09; Washington – June 2009 Aspen Institute Health Forum; Aspen, Colorado - July 2009 American Association of Diabetes Educators Annual Meeting; Atlanta, GA – August 2009 European Association for the Study of Diabetes; Vienna – September/October 2009 Cardiometabolic Health Congress; Boston – October 2009 International Diabetes Federation Congress; Montreal – October 2009 9th International Conference on New Trends in Immunosuppression & Immunomodulation; Geneva, Switzerland – February 2010 International Conference on Advanced Technologies and Treatments for Diabetes; Basel, Switzerland – February 2010 10th Annual Rachmiel Levine Diabetes and Obesity Symposium - Advances in Diabetes Biology, Immunology & Cell Therapy; Las Vegas, Nevada – March 2010 6th World Congress on Prevention of Diabetes; Dresden, Germany – April 2010 Egyptian Pediatric Diabetes Association; Cairo, Egypt – April 2010 American Diabetes Association, Annual Meeting; Orlando, FL - June 2010 European Association for the Study of Diabetes; Stockholm – September 2010 Cardiometabolic Health Congress; Boston – October 2010 XIV Congreso de la Asociacion Latinoamericana de Diabetes; Santiago, Chile – November 2010 Spanish Federation of Internal Medicine; Granada, Spain – January 2011 International Conference on Advanced Technologies and Treatments for Diabetes; London – February 2011 90th Anniversary of Insulin Conference, Beijing University; Beijing, China – May 2011 European Association for the Study of Diabetes; Lisbon – September 2011 Juvenile Diabetes Research Foundation Workshop on Immmunotherapy; Lisbon – September 2011 Cardiometabolic Health Congress; Boston – October 2011 International Society of Pediatric and Adolescent Diabetes; Miami – October 2011 International Conference on Advanced Technologies and Treatments for Diabetes; Barcelona – February 2012 12th Annual Rachmiel Levine Diabetes and Obesity Symposium; Pasadena, California – February 2012 Sociedad Española de Endocrinología y Nutrición; Oveido – May 2012 Immunology of Diabetes Society; Victoria, British Columbia – June 2012 European Association for the Study of Diabetes; Berlin – October 2012 Cardiometabolic Health Congress; Boston – October 2012 International Diabetes Summit; Columbus, Ohio – November 2012 Frontiers in Diabetes, Naomi Berrie Diabetes Center at Columbia University; New York, NY – November 2012 90th Anniversary of Insulin Symposium; Barcelona, Spain – February 2013 International Conference on Advanced Technologies & Treatments for Diabetes; Paris – February 2013 Diabetes UK Type 1 Immunotherapy Symposium; London, UK – May 2013 VII Konferenca Slovenskih Zdravnikov Iz Sveta In Slovenue; Ljubljana, Slovenia – June 2013 Diabetes Education Program; Potorož, Slovenia – June 2013 European Association for the Study of Diabetes; Barcelona – September 2013 Cardiometabolic Health Congress; Boston – October 2013 XV Congreso de la Asociacion Latinoamericana de Diabetes; Cancun, Mexico – November 2013 International Diabetes Federation Congress; Melbourne, Australia – December 2013 Immunology of Diabetes Society; Lorne, Australia – December 2013 International Conference on Advanced Technologies & Treatments for Diabetes; Vienna – February 2014 2nd African Diabetes Congress; Yaounde, Cameroon – February 2014 Jay S. Skyler Page 27 Curriculum Vitae American Diabetes Association, Annual Meeting; San Francisco - June 2014 Endocrine Society Fellows Program; Chicago – June 2014 European Association for the Study of Diabetes; Vienna – September 2014 Peruvian Diabetes Association; Lima – October 2014 Cardiometabolic Health Congress; Boston – October 2014 International Conference on Advanced Technologies & Treatments for Diabetes; Paris – February 2015 Cardiometabolic Health Congress; Boston – October 2015 10. THESIS AND DISSERTATION ADVISING Member, Ph.D. Dissertation Committee - Clarissa S. Scott Degree Awarded, 1980 Member, Ph.D. Dissertation Committee - Donna Follansbee Degree Awarded, 1982 Member, M.S. Thesis Committee - Adelle Platina Degree Awarded, 1985 Member, Ph.D. Dissertation Committee - Suzanne Klemp Degree Awarded, 1986 Member, M.S. Thesis Committee - Arnold Peckerman Degree Awarded, 1989 Member, Ph.D. Dissertation Committee - Rosemary D. Pasin Degree Awarded, 1989 Member, Ph.D. Dissertation Committee - Richard Nelesen Degree Awarded, 1989 Member, Ph.D. Dissertation Committee - Patricia Wick Degree Awarded, 1990 Member, M.S. Thesis Committee - Peggy Greco Degree Awarded, 1990 Member, Ph.D. Dissertation Committee - Dante Spetter Degree Awarded, 1991 Member, Ph.D. Dissertation Committee - Jane Ansley Degree Awarded, 1991 Member, M.S. Thesis Committee - Ruth Quillian Degree Awarded, 1991 Member, M.S. Thesis Committee - Julie Landel Degree Awarded, 1993 Member, Ph.D. Dissertation Committee - Clifford A. Massie Degree Awarded, 1993 Member, Ph.D. Dissertation Committee - Julie Landel Degree Awarded, 1995 Member, Ph.D. Dissertation Committee - Alissa Sheldon Degree Awarded, 1995 Member, Ph.D. Dissertation Committee - Catherine Davis Degree Awarded, 1997 Member, Ph.D. Dissertation Committee – Rita Goldstein Degree Awarded, 1998 Member, Ph.D. Dissertation Committee – Jeffrey Kibler Degree Awarded, 1998 Member, Ph.D. Dissertation Committee, University of Leuven – Kristia Casteels Degree Awarded, 1998 Member, Ph.D. Dissertation Committee – Carol Gallaher Degree Awarded, 1999 Member, M.S. Thesis Committee – Johanna Klaus Degree Awarded, 2001 Member, Ph.D. Dissertation Committee – Johanna Klaus Degree Awarded, 2004 Jay S. Skyler Page 28 Member, Ph.D. Dissertation Committee – Candace Hart Degree Awarded, 2005 Member, MPH Thesis Committee – Carlos Hernandez-Cassis Degree Awarded, 2008 Curriculum Vitae 11. CURRENT AND PAST TEACHING RESPONSIBILITIES Organizational Coordinator, Zoology 198.81, Man and Disease, Duke University Trinity College of Arts and Sciences: Spring 1972; Spring 1973 Coordinator, Division of Endocrinology Basic Seminar Series, Duke University Medical Center: Spring 1972; Fall 1972; Spring 1973 Co-Coordinator, Medicine 262, Diabetes Mellitus: A Camping Experience, Duke University School of Medicine: Summers of 1972 to 1976 Coordinator, Medicine 110-111, Clinical Medicine I & II; Medicine 120-121, Patient Evaluation I & II; Physician's Associate Program, Duke University: Fall 1972; Spring 1973 Co-Coordinator, Nursing 187, Patient Assessment, Duke University School of Nursing: Fall 1972; Spring 1973 Coordinator, Medicine and Community Health Sciences Clinical Courses, Physician's Associate Program, Duke University: July 1972 - June 1973 Lecturer, Sex Education, Immaculata School, Durham, NC: 1972 - 1973 Coordinator, Endocrinology Conferences, Department of Medicine, George Washington University: November 1973 - June 1974 Coordinator, Mechanisms of Disease: Endocrinology and Metabolism, University of Miami School of Medicine: 1978 - 1981 Coordinator, Diabetes Clinical Electives, Department of Medicine, University of Miami School of Medicine: 1978 - 1986 Director, “Optimizing Diabetes Management”, Recurring 5-Day Postgraduate Course (4-8 times yearly), University of Miami: 1979 - 1986 Director, “Diabetes Therapy in the 1980s”, University of Miami & Pfizer Laboratories, Miami, FL: December 1979 Chairman, “Symposium on Diabetes Mellitus”, University of Miami & Upjohn Co., Doral Country Club, Miami, FL: March 1980 Director, Postgraduate Course “Diabetes Mellitus: Update 1980”, University of Miami & Eli Lilly Co., Bal Harbour, FL: November 1980 Chairman, Symposium “Insulin Update 1982”, University of Miami & Eli Lilly Co., Key Biscayne, FL: December 1981 Director, American Diabetes Association Twenty-Ninth National Postgraduate Course, Orlando, FL: January 1982 Co-Chairman, “International Symposium on Type I Diabetes”, University of Miami & Squibb-Novo, Inc., Copenhagen, Denmark: September 1984 Director, Postgraduate Course “Diabetic Complications 1987”, University of Miami & Roerig/Pfizer, Miami, FL: November 1986 Director, American Diabetes Association Thirty-Fourth National Postgraduate Course, Orlando, FL: January 1987 Director, Postgraduate Course “Diabetes & Its Vascular Complications”, University of Miami & HoechstRoussel, Miami, FL: February 1987 Coordinator, Mechanisms of Disease: Endocrinology and Metabolism, University of Miami School of Medicine: 1989 Chairman, Cardiovascular Teaching Symposium, University of Miami & Merck Sharp & Dohme, Fort Lauderdale, FL - May 1989 Director, Postgraduate Course “Diabetic Complications: Update 1992”, University of Miami, Miami, FL: April 1992 Chairman, Diabetology Consultant Meeting on Magnesium Supplementation, Las Vegas, Nevada: June 1993 Coordinator, Combined Grand Rounds, Divisions of Endocrinology and of Diabetes & Metabolism, Department of Medicine, University of Miami and Miami Veterans Administration Medical Center: 1993-2000 Jay S. Skyler Page 29 Curriculum Vitae Chairperson, Insulin Dependent Diabetes - Recent Developments in Prediction, Prevention, and Treatment, International Business Communications (IBC-USA), Miami, FL: January 1994 Director, Postgraduate Course “The Insulin Resistance Syndrome”, University of Miami & Bristol-Myers Squibb, Miami, FL: June 1995, January 1996 Director, Postgraduate Course “Hypertension Update”, University of Miami & Merck Human Health, Miami, FL: November 1995 Director, Special Course for Korean Physicians “Diabetes and Its Complications: Realistic Expectations For Effective Therapies”, University of Miami & Wyeth-Ayerst International, Miami, FL: February 1996 Director, Postgraduate Course “Diabetes In The Primary Care Setting”, University of Miami & Bristol-Myers Squibb, Miami, FL: August 1997, October 1997, May 1998; November 1998; June 1999 Director, Diabetes Pre-Session Course, American College of Physicians Annual Meeting; San Diego, CA: April 1998 Chairman, Organizing Committee, NIH Workshop on Future Directions for Prevention of Type 1 Diabetes, Miami, FL: January 2000 Director, American Diabetes Association Forty-Seventh National Postgraduate Course, Honolulu, Hawaii: January 2000 Co-Chairman, American Diabetes Association Clinical Education Program “Insulin Therapy in the 21 st Century”: 2002-2003 Chairman, Organizing Committee, TrialNet Retreat on Immunologic Mechanisms & Animal Models for Type 1 Diabetes, Washington, DC: September 2003 Co-Chairman, NovoNordisk Diabetes Summit Dallas: April 2005 Co-Chairman, Cardiometabolic Health Congress Boston: October 2006 Director, American Diabetes Association Fifty-Fourth National Postgraduate Course, New York City: February 2007 Co-Chairman, NovoNordisk Diabetes Summit Orlando: March 2007 Co-Chairman, Cardiometabolic Health Congress Boston: September 2007 Director, American Diabetes Association Fifty-Fifth National Postgraduate Course, San Francisco: January/February 2008 Co-Chairman, Cardiometabolic Health Congress Boston: October 2008 Co-Chairman, Cardiometabolic Health Congress Boston: October 2009 Co-Chairman, University of Colorado Keystone Diabetes Conference Keystone, Colorado: July 2010 Co-Chairman, Cardiometabolic Health Congress Boston: October 2010 Co-Chairman, University of Colorado Keystone Diabetes Conference Keystone, Colorado: July 2011 Director, Rising Stars Program at the University of Miami: July 2011 Co-Chairman, International Society of Pediatric and Adolescent Diabetes; Miami – October 2011 Co-Chairman, Cardiometabolic Health Congress Boston: October 2011 Co-Chairman, University of Colorado Keystone Diabetes Conference Keystone, Colorado: July 2012 Director, Rising Stars Program at the University of Miami: July-August 2012 Co-Chairman, Cardiometabolic Health Congress Boston: October 2012 Co-Chairman, University of Colorado Keystone Diabetes Conference Keystone, Colorado: July 2013 Director, Rising Stars Program at the University of Miami: August 2013 Co-Chairman, Cardiometabolic Health Congress Boston: October 2013 Co-Chairman, University of Colorado Keystone Diabetes Conference Keystone, Colorado: July 2014 Jay S. Skyler Page 30 Co-Chairman, Cardiometabolic Health Congress Boston: October 2014 Co-Chairman, Cardiometabolic Health Congress Boston: October 2015 Curriculum Vitae Teaching (University of Miami) General Internal Medicine, Third & Fourth Year Medical Students, and House Staff: 1976 - 2005 Mechanisms of Disease, Endocrinology and Metabolism, Second Year Medical Students: 1977 - 2003 Mechanisms of Disease, Endocrinology and Metabolism, Ph.D.-M.D. Students: 1977 - 1989 Endocrinology and Metabolism, and Diabetes Clinical Electives, Fourth Year Medical Students and House Staff: 1976 - 2012 Introduction to the Patient, First Year Medical Students: 1981 - 1983 Endocrinology Core Course, First Year Medical Students: 1984 – 2001 Endocrinology Diabetes & Metabolism Core Course, Second Year Medical Students: 2004 - 2012 13. PATENTS ISSUED United States Patent # 5,422,125 Skyler, Jay S.; Frost, Phillip; Hahn, Elliot F. Method and composition for treatment of insulin resistance syndromes Filed: October 12, 1994; Issued: June 6, 1995 13. OTHER PROFESSIONAL ACTIVITIES (Selected) Florida Department of Health & Rehabilitative Services Division of Children's Medical Services Director, Southeast Florida Regional Diabetes Program for Children and Youth: 1977-1986 North Carolina Camp for Children with Diabetes Physician & Medical Director: 1970-1980, 1982 Consultant: 1981, 1983-1985 International Workshops on Diabetes and Camping Planning Committee, First Three Workshops: 1974-1976 Chairman, Planning Committee, Second Workshop: 1975 Eagles Nest Camp Foundation Board of Trustees: 1976-2000; Emeritus Trustee: 2000-Present Chairman, Committee on Diabetes Camping: 1976-1979 Executive Committee: 1978-1981 The National Foundation - March of Dimes Grant Reviewer: 1979 Washington University Diabetes Research and Training Center Ad Hoc Reviewer: 1980, 1989 The Educational Foundation of America Ad Hoc Reviewer: 1980 The Kroc Foundation Ad Hoc Reviewer: 1982 Canadian Diabetes Association Ad Hoc Reviewer: 1984, 1986, 1987 The John D. & Catherine T. MacArthur Foundation Grant Reviewer: 1985 Diabetes and Behavioral Medicine Study Group Member, 1986-1988 University of Massachusetts Diabetes/Endocrinology Research Center Ad Hoc Reviewer: 1985 University of Pennsylvania Diabetes/Endocrinology Research Center Ad Hoc Reviewer: 1990, 1991 Jay S. Skyler Page 31 Curriculum Vitae Sansum Research Foundation Consultant: 1997 National Multiple Sclerosis Society Consultant: 2006 National Institutes of Diabetes Digestive & Kidney Diseases Intramural Program Ad Hoc Reviewer: 2006 Netherlands Organisation for Health Research and Development Ad Hoc Reviewer: 2007 Australian National Health and Medical Research Council Ad Hoc Reviewer: 2007 US Civilian Research & Development Foundation Ad Hoc Reviewer: 2007 National Institutes of Health Clinical Center Ad Hoc Reviewer: 2008 University of Washington Diabetes/Endocrinology Research Center Ad Hoc Reviewer: 2008 University of Leuven (K.U.Leuven) Ad Hoc Reviewer: 2008, 2012, 2013 Leiden University Medical Center Ad Hoc Reviewer: 2009 Harvard Medical School Promotions & Tenure Committee: Special Member: 2014, 2015 Jay S. Skyler Page 32 Curriculum Vitae BIBLIOGRAPHY 1. SCIENTIFIC ARTICLES 1) Kredich NM, Skyler JS, Foote LJ: A Rapid and Quantitative Method for Determination of Antibodies to DNA in Systemic Lupus Erythematosus. Archives of Internal Medicine 1973; 131:639-644 2) Skyler JS, Ellis GJ, Delcher HK: Carolinas' Camp for Diabetic Children. I. Report of First Five Years of Operation. North Carolina Medical Journal 1973; 34:935-938 3) Skyler JS, Ellis GJ, Bivins CH: Carolinas' Camp for Diabetic Children. II. Descriptive Features of a Camper Population with Emphasis on Complications. North Carolina Medical Journal 1974; 35:29-32 4) Skyler JS, Neelon FA, Arnold WG, Kelley WN, Lebovitz HE: Growth Retardation in the Lesch-Nyhan Syndrome. Acta Endocrinologica 1974; 75:3-10 5) Lebovitz HE, Skyler JS, Boyd AE: L-DOPA and Growth Hormone Secretion in Man. Advances in Neurology 1974; 5:461-469 6) Chrambach A, Skyler JS: The Application of Steady State Stacking to Macromolecular Fractionation by Polyacrylamide Gel Electrophoresis. Protides of the Biological Fluids 1975; 22:701-713 7) Skyler JS: Camping for Youths with Diabetes Mellitus: Results and Analysis a Survey of Camps, 1973. In: Etzwiler DD, Robb J (Eds), Proceedings of the First International Workshop on Diabetes and Camping, Diabetes Education Center, Minneapolis, 1974, pp 27-42 8) Skyler JS, Newborg, BC, Peschel RL, Kempner W: Treatment of Massive Obesity. In: Howard A (Ed), Recent Advances in Obesity Research, Newman Press, London, 1975; 1:284-285 9) Feldman JM, Bivins CH, Skyler JS, Lebovitz HE: Effects of Cyproheptadine on Insulin and Growth Hormone Secretion in Acromegalic, Diabetic and Normal Subjects. Hormone and Metabolic Research 1975; 7:279-283 10) Kempner W, Newborg BC, Peschel RL, Skyler JS: Treatment of Massive Obesity with Rice/Reduction Diet Program: An Analysis of 106 Patients with at Least 45 Kilograms Weight Lost. Archives of Internal Medicine 1975; 135:1575-1584 11) Knazek RA, Skyler JS: Polypeptide Hormone Production by Cells Cultured on Artificial Capillaries. In: Pecile A, Mueller E (Eds), Growth Hormone and Related Peptides, Excerpta Medica, Amsterdam, 1976, pp 386-395 12) Knazek RA, Skyler JS: Secretion of Human Prolactin In Vitro. Proceedings of the Society of Experimental Biology and Medicine 1976; 151:561-564 13) Jimmerson DC, Post RM, Skyler JS, Bunney WE: A Preliminary Report: Neuroendocrine Effects of Dopamine and Norepinephrine Receptor Stimulators. Psychopharmacology Bulletin 1976; 12 (4):24-26 14) Slater S, De La Vega CE, Skyler JS, Murphy DL: Plasma Prolactin Stimulation by Fenfluramine and Amphetamine. Psychopharmacology Bulletin 1976; 12 (4):26-27 15) Zweerink HJ, Morgan EM, Skyler JS: Reovirus Morphogenesis: Characterization of Subviral Particles in Infected Cells. Virology 1976; 73:442-453 16) Jimmerson DC, Post RM, Skyler JS, Bunney WE: Prolactin in Cerebrospinal Fluid and Dopamine Function in Man. Journal of Pharmacy and Pharmacology 1976; 28:845-847 17) Skyler JS, Rogol AD, Lovenberg W, Knazek RA: Characterization of Growth Hormone and Prolactin Produced by Human Pituitary in Culture. Endocrinology 1977; 100:283-291 18) Skyler JS, Baumann G, Chrambach A: A Catalogue of Isohormones of Human Growth Hormone Based on Quantitative Polyacrylamide Gel Electrophoresis. Acta Endocrinologica Supplementum 1977; 211:1-40 19) Skyler JS, Chrambach A, Li CH: Quantitative Polyacrylamide Gel Electrophoresis and Specific Activities of Human Growth Hormone and Its Derivatives. Biochimica et Biophysica Acta 1977; 491:566-572 20) Lebovitz FL, Ellis GJ, Skyler JS: Increased Independence in Management of Diabetes Mellitus After Attending Summer Camp. Diabetes Care 1978; 1:23-26 Jay S. Skyler Page 33 Curriculum Vitae 21) Skyler JS, Lasky IA, Skyler DL, Robertson EG, Mintz DH: Home Blood Glucose Monitoring As An Aid In Diabetes Management. Diabetes Care 1978; 1:150-157 22) Skyler JS, Ellis GJ, Skyler DL, Lasky IA, Lebovitz FL: Instructing Patients in Making Alterations in Insulin Dosage. Diabetes Care 1979; 2:39-45 23) Skyler JS, O'Sullivan MJ, Robertson EG, Skyler DL, Lasky IA, Holsinger KK, McLeod AGW, Burkett G, Mintz DH: Blood Glucose Control During Pregnancy. Diabetes Care 1980; 3:69-76 24) Skyler JS, Alberti KGMM: Clinical Assessment of Metabolic Control in Insulin-Dependent Diabetes Mellitus. Diabetes Care 1980; 3:369-370 25) Skyler JS, O'Sullivan MJ, Holsinger KK: The Relationship Between Maternal Glycemia and Macrosomia. Diabetes Care 1980; 3:433-434 26) Linn MW, Linn BS, Skyler JS, Harris R: The Importance of Self-Assessed Health in Patients with Diabetes. Diabetes Care 1980; 3:599-606 27) Jimmerson DC, Post RM, Van Kammen DP, Skyler JS, Brown GL, Bunney WE: Cerebrospinal Fluid Cortisol Levels in Depression and Schizophrenia. American Journal of Psychiatry 1980; 137:979-980 28) Skyler JS, Skyler DL, Seigler DE, O'Sullivan MJ: Algorithms for Adjustment of Insulin Dosage by Patients Who Monitor Blood Glucose. Diabetes Care 1981; 4:311-318 29) Reeves M, Forhan SE, Skyler JS, Peterson CM: Comparison of Methods for Blood Glucose Monitoring. Diabetes Care 1981; 4:404-406 30) Skyler JS, Seigler DE, Reeves ML: Optimizing Pumped Insulin Delivery. Diabetes Care 1982; 5:135-139 31) Reeves M, Seigler DE, Ryan EA, Skyler JS: Glycemic Control in Insulin-Dependent Diabetes Mellitus: Comparison of Outpatient Intensified Conventional Therapy with Continuous Subcutaneous Insulin Infusion. American Journal of Medicine 1982; 72:673-680 32) Harris R, Skyler JS, Linn MW, Pollack L, Tewksbury D: Relationship Between the Health Belief Model and Compliance As a Basis for Intervention in Diabetes Mellitus. Pediatric and Adolescent Endocrinology 1982; 10:123-132 33) Lieberman LS, Rosenbloom AL, O'Malley B, Malone JI, Skyler JS: Institutionally-Based Diabetes Educational Services for Patients and their Families in Florida. Journal of the Florida Medical Association 1982; 69:23-31 34) Seigler DE, Reeves ML, Skyler JS: Lack of Effect of Improved Glycemic Control on C-Peptide Secretion in Patients Without Residual B-Cell Function. Diabetes Care 1982; 5:334-336 35) Seigler DE, LaGreca A, Citrin WS, Reeves ML, Skyler JS: Psychological Effects of Intensification of Diabetic Control. Diabetes Care 1982; 5 (Suppl. 1):19-23 36) Linn MW, Linn BS, Skyler JS, Jensen J: Stress and Immune Function in Diabetes Mellitus. Clinical Immunology and Immunopathology 1983; 27:223-233 37) Ryan EA, Miller J, Skyler JS: Finger Sepsis - A Possible Complication of Self-Monitoring of Blood Glucose. British Medical Journal 1983; 286:1614-1615 38) Duncan BB, Schmidt MI, Skyler JS, Ellis GJ, Keller A, Rathjens M: The Flashlight Test Lacks Validity As a Screen for Nocturnal Hypoglycemia. Diabetes Care 1984; 7:269-272 39) Reeves ML, Seigler DE, Ayyar DR, Skyler JS: Medical Plantar Sensory Response: A Sensitive Indicator of Peripheral Nerve Dysfunction in Patients with Diabetes Mellitus. American Journal of Medicine 1984; 76:842-846 40) Goldberg RB, Reeves ML, Seigler DE, Ryan EA, Miller N, Hsia SL, Skyler JS: Lack of a Persistent Reduction in Serum Lipid & Apoprotein Levels in Insulin-Dependent Diabetic Patients Receiving Intensified Insulin Treatment. Acta Diabetologia Latina 1985; 22:93-101 41) Ryan EA, O'Sullivan MJ, Skyler JS: Insulin Action During Pregnancy: Studies with the Euglycemic Clamp Technique. Diabetes 1985; 34:380-389 Jay S. Skyler Page 34 Curriculum Vitae 42) Boulton AJM, Bowker JH, Gadia M, Lemerman R, Caswell K, Skyler JS, Sosenko JM: The Use of Plaster Casts in the Management of Diabetic Neuropathic Foot Ulcers. Diabetes Care 1986; 9:149-152 43) Boulton AJM, Cutfield RG, Abouganem D, Angus E, Flynn HW, Skyler JS, Penneys NS: Necrobiosis Lipoidica Diabeticorum: A Clinicopathological Study and Review of the Literature. Journal of the American Academy of Dermatology 1988; 18:530-537 44) Boulton AJM, Kubrusly DB, Bowker JH, Gadia M, Quintero LC, Becker, DM, Skyler JS, Sosenko JM: Risk Factors for Diabetic Foot Ulcers. Diabetic Medicine 1986; 3:335-337 45) Sosenko JM, Boulton AJM, Kubrusly DB, Weintraub JK, Pasin RA, Schneiderman N, Skyler, JS: Autonomic Function and Heart Rate in Young Diabetic Patients. Journal of Pediatric Endocrinology 1985; 1:207-210 46) Sosenko JM, Boulton AJM, Kubrusly DB, Weintraub JK, Skyler, JS: The Vibratory Perception Threshold in Young Diabetic Patients: Associations with Glycemia and Puberty. Diabetes Care 1985; 8:605-607 47) Sosenko JM, Kubrusly DB, Goldberg RB, Fournier AM, Hsia SL, Gadia MT, Skyler JS: High Density Lipoprotein Components and Variation of Glycemia in Nondiabetic Individuals. Archives of Internal Medicine 1986; 146:1521-1524 48) Sosenko JM, Gadia MT, Fournier AM, O'Connell MT, Aguiar MC, Skyler JS: Body Stature: A Major Risk Factor for Diabetic Peripheral Neuropathy. American Journal of Medicine 1986; 80:1031-1034 49) Fournier AM, Gadia MT, Kubrusly DB, Skyler JS, Sosenko JM: Blood Pressure, Insulin, and Glycemia in Non-Diabetic Individuals. American Journal of Medicine 1986; 80:861-864 50) Harris R, Linn MW, Skyler JS, Sandifer R: Development of the Diabetes Health Beliefs Scale (DHBS). Diabetes Educator 1987; 13:292-297 51) Gadia MT, Natori N, Ramos LB, Ayyar DR, Skyler JS, Sosenko JM: The Influence of Height on Neurofunctional, Nerve Conduction, and Clinical Indices of Diabetic Peripheral Neuropathy. Diabetes Care 1987; 10:613-616 52) Sosenko JM, Gadia MT, Natori N, Ramos LB, Ayyar DR, Ramos LB, Skyler JS: Neurofunctional Testing for the Detection of Diabetic Peripheral Neuropathy. Archives of Internal Medicine 1987; 147:1741-1744 53) Sosenko JM, Boulton AJM, Gadia MT, Ward JD, Skyler JS: The Association Between Symptomatic Sensory Neuropathy and Body Stature in Diabetic Patients. Diabetes Research & Clinical Practice 1988; 4:95-98 54) Gadia MT, Skyler JS, Sosenko JM: The Association Between Heart Rate and Glycemia in Adult Diabetic Subjects. Diabetes Research & Clinical Practice 1988; 5:25-29 55) Satin W, LaGreca AM, Zigo MA, Skyler JS: Diabetes in Adolescence: Effects of Multi-Family Group Therapy and Parent Simulation of Diabetes. Journal of Pediatric Psychology 1989; 14:259-276 56) LaGreca AM, Follansbee D, Skyler JS: Developmental and Behavioral Aspects of Diabetes Management Among Children and Adolescents. Childrens Health Care 1990; 19:132-139 57) Boulton AJM, Levin S, Comstock J, and the North American Tolrestat in Neuropathy Research Group [Skyler JS – Study Group Participant]. A Multicentre Trial of the Aldose Reductase Inhibitor, Tolrestat, in Patients with Symptomatic Diabetic Neuropathy. Diabetologia 1990; 33:431-437 58) Martinez R, Rietberg B, Skyler J, Oster JR, Perez GO. Effect of Hyperkalemia on Insulin Secretion. Experentia 1991; 47:270272 59) Peckerman A, Saab PG, McCabe PM, Skyler JS, Winters RW, Llabre MM, Schneiderman N. Blood Pressure Reactivity and Perception of Pain During the Forehead Cold Pressor Test. Psychophysiology 1991; 28:485-495 60) Seigler DE, Olsson GM, Agramonte RF, Lohman VL, Ashby MH, Reeves ML, Skyler JS: Pharmacokinetics of Long-Acting (Ultralente) Insulin Preparations. Diabetes Nutrition & Metabolism 1991; 4:267-273. 61) Skyler JS, Rabinovitch A, and the Miami Cyclosporine Diabetes Study Group [Skyler JS, Rabinovitch A, Agramonte R, Lohman V, Reeves ML, Goldberg RB, Shienvold FL, Esquenazi V, Fletcher MA, Palmberg PF, Mintz DH, Ashby M, Sumowski W, Rathjens M, Miceli G, Winter D, Winslow C, Ferstenberg LB, Rodbard D]: Cyclosporine in Recent Onset Type I Diabetes Mellitus: Effects on Islet Beta Cell Function. Journal of Diabetes and Its Complications 1992; 6:77-88. 62) Hirsch IB, Farkas-Hirsch R, Herbst JS, Skyler JS: The Effect of Ejaculation on Albumin Excretion Rate. Journal of Diabetes and Its Complications 1992; 6:163-165. Jay S. Skyler Page 35 Curriculum Vitae 63) Seigler DE, Olsson GM, Skyler JS: Morning versus Bedtime NPH Insulin in Type II (Non-Insulin Dependent) Diabetes Mellitus. Diabetic Medicine 1992; 9:826-833. 64) Skyler JS, Lorenz TJ, Schwartz S, Eisenbarth GS, Einhorn D, Palmer JP, Marks JB, Greenbaum C, Saria EA, Byers V, and the CD5-Plus Diabetes Project Team: Effects of An Anti-CD5 Immunoconjugate (CD5-Plus) in Recent Onset Type I Diabetes Mellitus A Preliminary Investigation. Journal of Diabetes and Its Complications 1993; 7:224-232. 65) Burke GW, Cirocco R, Markou M, Agramonte RF, Rabinovitch A, Miller J, Skyler JS: Effect of Cyclosporine A on Serum Tumor Necrosis Factor in New Onset Type I (Insulin-Dependent) Diabetes Mellitus. Journal of Diabetes and Its Complications 1994; 8:40-44. 66) Hurwitz BE, Quillian RE, Marks JB, Schneiderman N, Freeman CR, LaGreca AM, Nagel JH, Agramonte RF, Skyler JS: Resting Cardiac Parasympathetic Status and Cardiovascular Response to Challenge in Type I Insulin Dependent Diabetes Mellitus. International Journal of Behavioral Medicine 1994; 1:137-162. 67) Radziuk J, Pye S, Seigler DE, Skyler JS, Offord R, Davies G: Splanchnic and Systemic Absorption of Intraperitoneal Insulin Using a New Double Tracer Method. American Journal of Physiology 1994; 266: (Endocrinology & Metabolism 29):E750-E759. 68) LaGreca AM, Swales T, Klemp S, Madigan S, Skyler JS: Adolescents with Diabetes: Gender Differences in Psychosocial Functioning and Glycemic Control. Childrens' Health Care 1995; 24:61-78. 69) Burke GW, Ricordi C, Karatzas T, Carreno M, Cirocco R, Ciancio G, Coker D, Quian T, Selvaggi G, Alejandro R, Skyler JS, Tzakis A, Roth D, Nery J, Miller J: Donor Bone Marrow Infusion in Simultaneous Pancreas/Kidney Transplant Recipients: A Preliminary Study. Transplantation Proceedings 1995; 27:3121-3122. 70) Burke GW, Alejandro R, Roth D, Colona J, Contreras N, Ciancio G, Skyler JS, Ricordi C, Nery J, Tzakis A, Miller J: Use of FK506 in Simultaneous Pancreas/Kidney Transplantation: Lack of Impairment of Glycemic or Lipid Metabolism. Transplantation Proceedings 1995; 27:3119-3120. 71) Burke GW, Alejandro R, Ciancio G, Nery J, Roth D, Shapiro R, Scantlebury V, Skyler JS, Ricordi C, Tzakis A, Miller J: The Use of FK-506 in Simultaneous Pancreas/Kidney Transplantation: Rescue, Induction, and Maintenance Immunosuppression. Transplantation Proceedings 1995; 27:3123-3124. 72) Laffel LM, McGill JB, Gans DJ for the North American Microalbuminuria Study Group [Skyler JS – Study Group Participant]. The Beneficial Effect of Angiotensin-Converting Enzyme Inhibition with Captopril on Diabetic Nephropathy in Normotensive IDDM Patients with Microalbuminuria. American Journal of Medicine 1995; 99:497-504. 73) Donahue RP, Prineas RJ, Donahue RC, Bean JA, Skyler JS: The Female “Insulin Advantage” in a Biracial Cohort: Results from The Miami Community Health Study. International Journal of Obesity 1996; 20:76-82. 74) The Microalbuminuria Captopril Study Group [Skyler JS – Study Group Participant]. [Boner G, Van Dyk DJ, Tan MH, Tan J, Ekstrand A, Koivisto VA, Groop LC, Groop PH, Lucas A, Romero R, Salinas I, Sanmarti A, Escobar F, Escobar-Jimenez F, Campos-Pastor MM, Mugoz M, Gomez M, Mangili R, Pozza G, Spotti D, Hansen KW, Christiansen JS, Klein F, Mogensen CE, Van Doorn LG, Spooren PFMJ, Cruickshank JK, Jervell J, Paus PN, Barnes DJ, Collins A, Viberti GC, Williams G, Nelstrop GA, Amorosa L, Anolik JR, Aronoff SL, Eubank B, Bailie M, Pelletier L, Blevins T, Charles MA, Perry M, Clarke D, Tomkey D, Einhorn D, Humphries D, Garber AJ, Haag B, Williams E, Hoy W, Watkins M, Kahkonen D, Kruger D, Kilo C, Laffel L , Golden E, Lodewick P, Lovinskyad, Mason J, Johnson S, McGill J, Schmidt L, Orlander P, Sorenson K, Raskin P , Hellenbrand D, Rosenblatt S, Schwartz S, Aufieri J, Sheehan JP, Ulchaker M, Skyler JS, Agramonte R, Starr J, Gagliastre D, Taylor T, Dawn K, Ward WK, Rigdon M.]. Captopril Reduces The Risk of Nephropathy in IDDM Patients With Microalbuminuria. Diabetologia 1996; 39:587-593. 75) Donahue RP, Donahue RC, Prineas RJ, Bean JA, Gutt M, Skyler JS, Schneiderman N: Insulin Sensitivity and Blood Pressure in a Biethnic Sample: The Miami Community Health Study. Journal of Clinical Epidemiology 1996; 49:859-864. 76) Anderson JH, Brunnelle RL, Koivisto VA, Pfutzner A, Trautmann ME, Vignati L, DiMarchi R, and the Multicenter Insulin Lispro Study Group [Skyler JS – Study Group Participant]. Reduction of Postprandial Hyperglycemia and Frequency of Hypoglycemia in IDDM Patients During Insulin Analog Treatment. Diabetes 1997; 46:265-270. 77) Weber SL, Gkonos PJ, Skyler JS: Combined Octreotide and Insulin Therapy in Acromegaly. Endocrine Practice 1997; 3:1921. 78) Burke GW, Ricordi C, Karatzas T, Carreno M, Markou M, Cirocco R, Ciancio G, Qian T, Selvaggi G, Alejandro R, Skyler JS, Roth D, Tzakis A, Miller J: Donor Bone Marrow Infusion in Simultaneous Pancreas/Kidney Transplantion with OKT3 Induction: Evidence for Augmentation of Chimerism. Transplantation Proceedings 1997; 29:1207-1208. 79) Donahue RP, Prineas RJ, Bean JA, Donahue RC, Goldberg RB, Skyler JS, Schneiderman N: The Relationship of Fasting Insulin to Blood Pressure in a Multiethnic Population: The Miami Community Health Study. Annals of Epidemiology 1998; 8:236-244. Jay S. Skyler Page 36 Curriculum Vitae 80) Burke GW, Ciancio G, Alejandro R, Roth D, Ricordi C, Skyler JS, Tzakis A, Miller J: Cholesterol Control: Long-Term Benefit of Pancreas-Kidney Transplantion with FK 506 Immunosuppression. Transplantation Proceedings 1998; 30:513-514. 81) Bril V, Ellison R, Ngo M, Bergstrom B, Raynard D, Gin H, and the Roche Neuropathy Study Group [Skyler JS – Study Group Participant]. Electrophysiological Monitoring in Clinical Trials. Muscle & Nerve 1998; 21:1368-1373. 82) Donahue RP, Prineas RJ, Donahue RD, Zimmet P, Bean JA, De Courten M, Collier G, Goldberg RB, Skyler JS, Schneiderman N. Is Fasting Leptin Associated with Insulin Resistance among Nondiabetic Persons? The Miami Community Health Study. Diabetes Care 1999; 22: 1092-1096. 83) Gutt M, Davis CL, Spitzer S, Llabre MM, Kumar M, Czarnnecki E, Schneiderman N, Skyler JS, Marks JB. Validation of the Insulin Sensitivity Index (ISI0,120): Comparison with Other Measures. Diabetes Research & Clinical Practice 2000; 47:177-184. 84) Donahue RP, Zimmet P, Bean JA, de Courtier M, Donahue RC, Collier G, Goldberg RB, Skyler JS, Schneiderman N, Prineas RJ: Cigarette Smoking, Alcohol Use and Physical Activity in Relation to Serum Leptin Levels in a Multiethnic Population: The Miami Community Health Study. Annals of Epidemiology 1999; 9:108-113. 85) Motivala SJ, Hurwitz BE, LaGreca AM, Llabre MM, Marks JB, Skyler JS, Schneiderman N. Aberrant Parasympathetic and Hemodynamic Function Distinguishes A Sub-Group of Psychologically-Distressed Individuals with Asymptomatic Type 1 Diabetes Mellitus. International Journal of Behavioral Medicine 1999; 6:78-94. 86) Davis CL, Gutt M, Llabre MM, Marks JB, O’Sullivan MJ, Potter JE, Landel JL, Schneiderman N, Kumar M, Gellman M, Skyler JS. History of Gestational Diabetes, Insulin Metabolism, and Coronary Risk. Journal of Diabetes and Its Complications 1999; 13:216-223. 87) Heller A, McGarraugh G, Feldman B, Bohannon N, Skyler J, DeLeeuw E, Clarke D. FreeStyle™ : A Small (300 nL ) Volume Electrochemical Glucose Sensor for Home Blood Glucose Testing. Diabetes Technology & Therapeutics 2000; 2:221-229. 88) Goldstein RZ, Hurwitz BE, Llabre MM, Schneiderman N, Gutt M, Skyler JS, Prineas RJ, Donahue RP. Modeling Preclinical Cardiovascular Risk for Use in Epidemiologic Studies: Miami Community Health Study. American Journal of Epidemiology 2001; 154:765-776.. 89) Bode B, Weinstein R, Bell D, McGill J, Nadeau D, Raskin P, Davidson J, Henry R, Huang WC, Reinhardt RR for The Insulin Aspart CSII Pump Study Group [Skyler JS – Study Group Participant]. Comparison of insulin aspart with buffered regular insulin and insulin lispro in continuous subcutaneous insulin infusion: a randomized study in type 1 diabetes. Diabetes Care 2002; 25:439-444. 90) Raskin P, Bode BW, Marks JB, Hirsch IB, Weinstein RL, Janet B. McGill JB, Peterson GE, Mudaliar SR, Reinhardt RR, and The Insulin Aspart CSII Study Group in Type 2 Diabetes [Skyler JS – Study Group Participant]. Continuous Subcutaneous Insulin Infusion and Multiple Daily Injection Therapy Are Equally Effective in Type 2 Diabetes: A randomized, parallel-group, 24-week study Diabetes Care 2003; 26:2598-2603 91) Hurwitz BE, Klimas NG, Llabre MM, Maher KJ, Skyler JS, Bilsker MS, McPherson-Baker S, Lawrence PJ, LaPerriere AR, Greeson JM, Klaus J, Lawrence R, Schneiderman N. HIV, Metabolic Syndrome X, Inflammation, Oxidative Stress, and Coronary Heart Disease Risk: Role of Protease Inhibitor Exposure. Cardiovascular Toxicology 2004; 4:303-316. 92) Bolton WK, Cattran DC, Williams ME, Adler SG, Appel GB, Cartwright K, Foiles PG, Freedman BI, Raskin P, Ratner RE, Spinowitz BS, Whittier FC, Wuerth JP; ACTION I Investigator Group [Skyler JS – Study Group Participant]. Randomized trial of an inhibitor of formation of advanced glycation end products in diabetic nephropathy. American Journal of Nephrology 2004; 24:32-40 93) Hurwitz BE, Klaus JR, Llabre MM, Gonzalez A, Lawrence PJ, Maher KJ, Greeson JM, Baum MK, Shor-Posner G, Skyler JS, Schneiderman N. Suppression of human immunodeficiency virus type 1 viral load with selenium supplementation: a randomized controlled trial. Archives of Internal Medicine 2007; 167:148-154. 94) Klaus JR, Hurwitz BE, Llabre MM, Skyler JS, Goldberg RB, Marks JB, Bilsker MS, Schneiderman N. Central Obesity and Insulin Resistance in the Cardiometabolic Syndrome: Pathways to Preclinical Cardiovascular Structure and Function. Journal of Cardiometabolic Syndrome 2009; 4:63–71. 95) Han D, Leyva CA, Della Matheson D, Mineo D, Messinger S, Blomberg BB, Hernandez A, Meneghini LF, Allende G, Skyler JS, Alejandro R, Pugliese A, Kenyon NS. Immune Profiling by Multiple Gene Expression Analysis in Patients At-risk and with Type 1 Diabetes. Clinical Immunology 2011; 139:290-301. 96) Faleo G, Fotino F, Bocca N, Molano RD, Zahr-Akraw E, Molina J, Villate S, Umland O, Skyler JS, Bayer AL, Ricordi C, Pileggi Jay S. Skyler Page 37 Curriculum Vitae A. Prevention of Autoimmune Diabetes and Induction of Beta-Cell Proliferation in NOD mice by Hyperbaric Oxygen Therapy. Diabetes 2012; 61:1769-1778. 97) Han D, Cai X, Wen J, Matheson D, Skyler JS, Kenyon NS, Chen Z. Innate and adaptive immune gene expression profiles as biomarkers in human type 1 diabetes. Clinical and Experimental Immunology 2012; 170:131-138. 98) Roep BO, Solvason N, Gottlieb PA, Abreu JR, Harrison LC, Eisenbarth GS, Yu L, Leviten M, Hagopian WA, Buse JB, von Herrath M, Quan J, King RS, Robinson WH, Utz PJ, Garren H; BHT-3021 Investigators, Steinman L [Skyler JS – Study Group Participant]. Plasmid-encoded proinsulin preserves C-peptide while specifically reducing proinsulin-specific CD8⁺ T cells in type 1 diabetes. Science Translational Medicine 2013 Jun 26;5(191):191ra82. doi: 10.1126/scitranslmed.3006103. 99) Garg SK, Buse JB, Skyler JS, Vaughn DE, Muchmore DB. Subcutaneous Injection of Hyaluronidase with Human Regular Insulin Compared with Insulin Lispro in Type 1 Diabetes. Diabetes Obesity Metabolism 2014; 16:1065-1069. 100) Eckel RC, Henry RR, Yue P, Dhalla A, Wong P, Jochelson P, Belardinelli L, Skyler JS. The effect of ranolazine monotherapy on glycemic control in subjects with type 2 diabetes mellitus. Diabetes Care 2015; 38:1189-1196. 101) Hurwitz BE, Schneiderman N, Marks JB, Mendez AJ, Gonzalez A, Llabre MM, Smith SR, Bizzotto R, Santini E, Manca ML, Skyler JS, Mari A, Ferrannini E. Adaptation of β-cell and Endothelial Function to Carbohydrate Loading: Influence of Insulin Resistance. Diabetes 2015; 64:2550-2559. 102) Skyler JS, Fonseca VA, Segal KR, Rosenstock J, on behalf of the MSB-DM003 Investigators. Allogeneic Mesenchymal Precursor Cells in Type 2 Diabetes: A Randomized, Placebo-controlled, Dose Escalation Safety and Tolerability Pilot Study. Diabetes Care 2015; 38:1742-1749. 103) Bode BW, Skyler JS, Hirsch IB, Garg SK, Buse JB, Zinman B, Rodbard D, Hompesch M, Morrow LA, Wu XW, Huang Y, Bruce SR, Vaughn DE, Muchmore DB. Pretreatment of Subcutaneous Insulin Infusion Sites with Recombinant Human Hyaluronidase Provides Consistent Acceleration of Rapid Acting Analog Insulin Absorption and Action with Improved Postprandial Glucose Control. Submitted for Publication. 104) Saab PG, McCalla JR, Spitzer SB, Musto AA, Llabre MM, Goldberg RB, Zhao F, Fitzpatrick S, LaPerriere A, Skyler JS, Hurwitz BE, Schneiderman N. Cardiovascular Risk in Adolescents: The Influence of Blood Pressure Status. Submitted for Publication. a. DPT-1 Study Group References 1) DPT-1 Study Group. The Diabetes Prevention Trial-Type 1 Diabetes (DPT-1) [Skyler JS – Study Group Chairman]. Implementation of Screening and Staging of Relatives. Transplantation Proceedings 1995; 27: 3377. 2) Greenbaum CJ, Schatz DA, Cuthbertson D, Zeidler A, Eisenbarth GS, Krischer JP, The Diabetes Prevention Trial–Type 1 Study Group [Skyler JS – Study Group Chairman]. Islet Cell Antibody-Positive Relatives With Human Leukocyte Antigen DQA1*0102, DQB1*0602: Identification by the Diabetes Prevention Trial-Type 1. Journal of Clinical Endocrinology & Metabolism 2000; 85:1255-1260 3) Greenbaum CJ, Cuthbertson D, Krischer JP, and the Diabetes Prevention Trial of Type 1 Diabetes Study Group [Skyler JS – Study Group Chairman]. Type 1 Diabetes Manifested Solely by 2-h Oral Glucose Tolerance Test Criteria. Diabetes 2001; 50:470-476 4) Chase HP, Cuthbertson DD, Dolan LM, Kaufman F, Krischer JP, Schatz DA, White NH, Wilson DM, Wolfsdorf J, The Diabetes Prevention Trial–Type 1 Study Group [Skyler JS – Study Group Chairman]. First-phase Insulin Release During The Intravenous Glucose Tolerance Test As A Risk Factor For Type 1 Diabetes. Journal of Pediatrics 2001; 138:244-249 5) Yu L, Cuthbertson DD, Maclaren N, Jackson R, Palmer JP, Orban T, Eisenbarth GS, Krischer JP, DPT-1 Participating Investigators [Skyler JS – Study Group Chairman]. Expression of GAD65 and Islet Cell Antibody (ICA512) Autoantibodies Among Cytoplasmic ICA+ Relatives Is Associated With Eligibility for the Diabetes Prevention Trial-Type 1. Diabetes 2001; 50: 1735-1740. 6) Diabetes Prevention Trial - Type 1 Diabetes Study Group [Skyler JS – Study Group Chairman]. Effects of Insulin in Relatives of Patients with Type 1 Diabetes Mellitus. New England Journal of Medicine 2002; 346:1685-1691. 7) Yu L, Cuthbertson DD, Eisenbarth GS, Krischer JP, DPT-1 Participating Investigators [Skyler JS – Study Group Chairman]. Diabetes Prevention Trial 1: Prevalence of GAD and ICA512 (IA-2) Autoantibodies by Relationship to Proband. Annals of the New York Academy of Sciences 2002; 958:254-258. 8) Krischer JP, Cuthbertson DD, Yu L, Orban T, Maclaren N, Jackson R, Winter WE, Schatz DA, Palmer JP, Eisenbarth GS, and The Diabetes Prevention Trial–Type 1 Study Group [Skyler JS – Study Group Chairman]. Screening Strategies for the Identification Jay S. Skyler Page 38 Curriculum Vitae of Multiple Antibody Positive Relatives of Individuals with Type 1 Diabetes. Journal of Clinical Endocrinology & Metabolism 2003; 88:103-108. 9) Redondo MJ, Fain PR, Krischer JP, Yu L, Cuthbertson D, Winter WE, Eisenbarth GS; on behalf of the DPT-1 Study Group [Skyler JS – Study Group Chairman]. Expression of beta-cell autoimmunity does not differ between potential dizygotic twins and siblings of patients with type 1 diabetes. Journal of Autoimmunity 2004; 23:275-279. 10) Krischer JP, Cuthbertson DD, Greenbaum C; Diabetes Prevention Trial-Type 1 Study Group [Skyler JS – Study Group Chairman]. Male sex increases the risk of autoimmunity but not type 1 diabetes. Diabetes Care 2004; 27:1985-1990. 11) Greenbaum CJ, Eisenbarth G, Atkinson M, Yu L, Babu S, Schatz D, Zeidler A, Orban T, Wasserfall C, Cuthbertson D, Krischer J, DPT-1 Study Group [Skyler JS – Study Group Chairman]. High Frequency of Abnormal Glucose Tolerance in DQA1*0102/DQB1*0602 Relatives Identified as Part of the Diabetes Prevention Trial – Type 1 Diabetes. Diabetologia 2005; 48:6874. 12) Diabetes Prevention Trial - Type 1 Diabetes Study Group [Skyler JS – Study Group Chairman]. Effects of Oral Insulin in Relatives of Patients with Type 1 Diabetes Mellitus. Diabetes Care 2005; 28:1068-1076. 13) Rhodes ET, Wolfsdorf JI, Cuthbertson DD, Feldman HA, Ludwig DS; Diabetes Prevention Trial-Type 1 Study Group [Skyler JS – Study Group Chairman]. Effect of low-dose insulin treatment on body weight and physical development in children and adolescents at risk for type 1 diabetes. Diabetes Care 2005; 28:1948-1953. 14) Sosenko JM, Palmer JP, Greenbaum CJ, Mahon J, Cowie C, Krischer JP, Chase HP, White NH, Buckingham B, Herold KC, Cuthbertson D, Skyler JS, and the Diabetes Prevention Trial-1 Study Group. Patterns of Metabolic Progression to Type 1 Diabetes in the Diabetes Prevention Trial–Type 1. Diabetes Care 2006; 29: 643-649. 15) Tsai EB, Sherry NA, Palmer JP, Herold KC, and the DPT-1 Study Group [Skyler JS – Study Group Chairman]. The Rise and Fall of Insulin Secretion in Type 1 Diabetes Mellitus. Diabetologia 2006; 49: 261-270. 16) Barker JM, McFann K, Harrison LC, Fourlanos S, Krischer JP, Cuthbertson D, Chase HP, Eisenbarth GS, and the DPT-1 Study Group [Skyler JS – Study Group Chairman]. Pre-Type 1 Diabetes Dysmetabolism: Maximal sensitivity achieved with both Oral and Intravenous Glucose Tolerance Testing. Journal of Pediatrics 2007; 150:31-36. 17) Redondo MJ, Babu S, Zeidler A, Orban T, Yu L, Greenbaum C, Palmer JP, Cuthbertson D, Eisenbarth GS, Krischer JP, Schatz D, and the DPT-1 Study Group [Skyler JS – Study Group Chairman]. Specific HLA DQ Influence on Expression of Anti-Islet Autoantibodies and Progression to Type 1 Diabetes. Journal of Clinical Endocrinology & Metabolism 2006; 91: 1705-1713. 18) Sosenko JM, Palmer JP, Greenbaum CJ, Mahon J, Cowie C, Krischer JP, Chase HP, White NH, Buckingham B, Herold KC, Cuthbertson D, Skyler JS, and the Diabetes Prevention Trial-1 Study Group. Increasing the accuracy of oral glucose tolerance testing and extending its application to individuals with normal glucose tolerance for the prediction of type 1 diabetes: the Diabetes Prevention Trial- Type 1. Diabetes Care 2007; 30:38-42. 19) Barker JM, McFann KK, Orban T, on behalf of the DPT-1 Study Group [Skyler JS – Study Group Chairman]. Effect of oral insulin on insulin autoantibody levels in the Diabetes Prevention Trial Type 1 oral insulin study. Diabetologia 2007; 50:1603-1606. 20) Xu P, Cuthbertson D, Greenbaum C, Palmer JP, Krischer JP, and Diabetes Prevention Trial-Type 1 Study Group [Skyler JS – Study Group Chairman]. The Role of Insulin Resistance in Predicting the Progression to Type 1 Diabetes. Diabetes Care 2007; 30:2314-2320. 21) Johnson SB, Baughcum AE, Hood K, Rafkin-Mervis LE, Schatz DA, for the DPT-1 Study Group [Skyler JS – Study Group Chairman]. Participant and Parent Experiences in the Parenteral Insulin Arm of the Diabetes Prevention Trial for Type 1 Diabetes. Diabetes Care 2007; 30: 2193-2197. 22) Sosenko JM, Krischer JP, Palmer JP, Mahon J, Cowie C, Greenbaum CJ, Cuthbertson D, Lachin JM, Skyler JS, and the Diabetes Prevention Trial-1 Study Group. A Risk Score for Type 1 Diabetes Derived from Autoantibody Positive Participants in The Diabetes Prevention Trial-Type 1. Diabetes Care 2008; 31: 528-533. 23) Sosenko JM, Palmer JP, Rafkin-Mervis L, Krischer J, Cuthbertson D, Matheson D, Skyler JS, and the DPT-1 Study Group. Glucose and C-peptide Changes in the Perionset Period of Type 1 Diabetes in the Diabetes Prevention Trial-Type 1. Diabetes Care 2008; 31: 2188-2192. 24) Butty V, Campbell C, Mathis D, Benoist C, and the Diabetes Prevention Trial-Type 1 Study Group [Skyler JS – Study Group Chairman]. Impact of diabetes susceptibility loci on progression from pre-diabetes to diabetes in at-risk individuals of the DPT1 trial. Diabetes 2008; 57: 2348-2359. Jay S. Skyler Page 39 Curriculum Vitae 25) Sherr J, Sosenko J, Skyler JS, Herold K. Prevention of Type 1 diabetes. The time has come. Nature Clinical Practice Endocrinology & Metabolism 2008; 4:334-343. 26) Johnson SB, Baughcum AE, Rafkin-Mervis LE, Schatz DA, for the DPT-1 Study Group [Skyler JS – Study Group Chairman]. Participant and parent experiences in the oral insulin study of the Diabetes Prevention Trial for Type 1 Diabetes. Pediatric Diabetes 2009; 10:177-183. 27) Sosenko JM, Palmer JP, Rafkin-Mervis L, Krischer J, Cuthbertson D, Skyler JS, and the DPT-1 Study Group. Incident Dysglycemia and the Progression to Type 1 Diabetes among Participants in the Diabetes Prevention Trial-Type 1. Diabetes Care 2009; 32: 1603-1607. 28) Triolo TM, Chase HP, Barker JM, for the DPT-1 Study Group [Skyler JS – Study Group Chairman]. Diabetic subjects diagnosed through the Diabetes Prevention Trial-Type 1 (DPT-1) are often asymptomatic with normal A1C at diabetes onset. Diabetes Care 2009; 32:769-773. 29) Orban T, Sosenko JM, Cuthbertson D, Krischer JP, Skyler JS Jackson R, Yu L, Palmer JP, Schatz DA, Eisenbarth GS, and the DPT-1 Study Group. Pancreatic Autoantibodies as Predictors of Type 1 Diabetes in the Diabetes Prevention Trial-Type 1 (DPT-1). Diabetes Care 2009; 32:2269-2274. 30) Ferrannini E, Mari A, Nofrate V, Sosenko JM, Skyler, JS, for the DPT-1 Study Group. Progression to diabetes in relatives of patients with type 1 diabetes: mechanisms and mode of onset. Diabetes 2010; 59:679-685. 31) Sosenko JM, Palmer JP, Rafkin-Mervis L, Krischer J, Cuthbertson D, Greenbaum CJ, Eisenbarth GS, Skyler JS, and the DPT-1 Study Group. Trends of Earlier and Later Responses of C-peptide to Oral Glucose Challenges with Progression to Type 1 Diabetes in Diabetes Prevention Trial-Type 1 Participants. Diabetes Care 2010; 33:620-625. 32) Sosenko JM, Skyler JS, Krischer JP, Greenbaum CJ, Rafkin LE, Cuthbertson D, Cowie C, Herold K, Eisenbarth GS, Palmer JP, and The Diabetes Prevention Trial-1 Study Group. Glucose Excursions between States of Glycemia with Progression to Type 1 Diabetes in the Diabetes Prevention Trial-Type 1 (DPT-1). Diabetes 2010; 58: 2386-2389. 33) Xu P, Wu Y, Zhu Y, Dagne G, Johnson G, Cuthbertson D, Krischer JP, Sosenko JM, Skyler JS, on behalf of the DPT-1 Study Group. Prognostic Performance of Metabolic Indexes in Predicting Onset of Type 1 Diabetes. Diabetes Care 2010; 33:2508-2513. 34) Vehik K, Haller MJ, Beam CA, Schatz DA, Wherrett DK, Sosenko JM, Krischer JP; DPT-1 Study Group [Skyler JS – Study Group Chairman]. Islet Autoantibody Seroconversion in the DPT-1 Study: Justification for repeat screening throughout childhood. Diabetes Care 2011; 34:358-62. 36) Greenbaum CJ, Buckingham, B, Chase HP, Krischer J, for the DPT-1 Study Group [Skyler JS – Study Group Chairman]. Metabolic tests to determine risk for type 1 diabetes in clinical trials. Diabetes Metabolism Research & Reviews 2011; 27:584-589. 37) Xu P, Beam C, Cuthbertson D, Sosenko JM, Skyler JS, Krischer JP, on behalf of the DPT-1 Study Group. Prognostic accuracy of immunologic and metabolic markers for type 1 diabetes in a high risk population: Receiver operating characteristic analysis. Diabetes Care 2012; 35:1975-1980. 38) Ismail H, Krischer J, Chase HP, Cuthbertson D, Palmer J and DPT-1 Study Group [Skyler JS – Study Group Chairman]. First Test Effect in Intravenous Glucose Tolerance Testing. Pediatric Diabetes 2013, Aug 5 Epub ahead of print. 39) Xu P, Qian X, Schatz DA, Cuthbertson D, Krischer JP, and the DPT-1 Study Group [Skyler JS – Study Group Chairman]. Distribution of C-Peptide and its Determinants in North American Children at Risk for Type 1 Diabetes. Diabetes Care 2014; 37:1959-1965.. 40) Lin Y, Qian X, Krischer JP, Vehik K, Lee HS, Huang S, for the DPT-1 Study Group [Skyler JS – Study Group Chairman]. A Rule-Based Prognostic Model for Type 1 Diabetes by Identifying and Synthesizing Baseline Profile Patterns. PLos One 2014; 9(6): e91095. doi:10.1371. 41) Hao W, Greenbaum CJ, Krischer JP, Cuthbertson D, Marks JB, Palmer JP, for the DPT-1 Study Group [Skyler JS – Study Group Chairman]. The Effect of DPT-1 Intravenous Insulin Infusion and Daily Subcutaneous Insulin on Endogenous Insulin Secretion and Postprandial Glucose Tolerance. Diabetes Care 2015; Feb 26. [Epub ahead of print] b. Type 1 Diabetes TrialNet Study Group References Jay S. Skyler Page 40 Curriculum Vitae 1) Skyler JS, Greenbaum CJ, Lachin JM, Leschek E, Rafkin-Mervis L, Savage P, Spain L, and the Type 1 Diabetes TrialNet Study Group. Type 1 Diabetes TrialNet – An International Collaborative Clinical Trials Network. Annals of the New York Academy of Sciences 2008; 1150: 14-24. 2) Skyler JS and the Type 1 Diabetes TrialNet Study Group. Update on Worldwide Efforts to Prevent Type 1 Diabetes. Annals of the New York Academy of Sciences 2008; 1150: 190-196. 3) Greenbaum CJ, Mandrup-Poulsen T, Friedenberg-McGee P, Battelino T, Haastert B, Ludvigsson J, Pozzilli P, Lachin JM, Kolb H, and The Type 1 Diabetes TrialNet Research Group [Skyler JS – Study Group Chairman] and The European C-peptide Trial Study Group. The Mixed Meal Tolerance Test versus the Glucagon Stimulation Test for the Assessment of Beta Cell Function in Therapeutic Trials in Type 1 Diabetes. Diabetes Care 2008; 31:1966-1971. 4) Mahon J, Sosenko JM, Rafkin-Mervis LE, Krause-Steinrauf H, Lachin JM, Thompson C, Bingley PJ, Bonifacio E, Palmer JP, Eisenbarth GS, Wolfsdorf J, Skyler JS, for the TrialNet Natural History Committee and Type 1 Diabetes TrialNet Study Group. The TrialNet Natural History Study of the Development of Type 1 Diabetes: objectives, design, and initial results. Pediatric Diabetes 2009: 10:97-104. 5) Chase HP, Leschek E, Rafkin-Mervis L, Krause-Steinrauf J, Chritton S, Asare SM, Adams S, Skyler JS, Clare-Salzler M, and the Type 1 Diabetes TrialNet NIP Study Group. Nutritional Intervention to Prevent (NIP) Type 1 Diabetes; A Pilot Trial. ICAN: Infant, Child, & Adolescent Nutrition 2009; 1:98-107. 6) Pescovitz MD, Greenbaum CJ, Krause-Steinrauf H, Becker DJ, Gitelman SE, Goland R, Gottlieb PA, Marks JB, McGee PF, Moran AM, Raskin P, Rodriguez H, Schatz DA, Wherrett D, Wilson DM, Lachin JM, Skyler JS, and The Type 1 Diabetes TrialNet AntiCD20 Study Group. Rituximab, B-lymphocyte Depletion and Preservation of Beta-cell Function. New England Journal of Medicine 2009; 361:2143-2152. 7) Gottlieb PA, Quinlan S, Krause-Steinrauf H, Greenbaum CJ, Wilson DM, Rodriguez H, Schatz DA, Moran AM, Lachin JM, Skyler JS, and the Type 1 Diabetes TrialNet MMF/DZB Study Group. Failure to Preserve beta-cell function with Mycophenolate Mofetil and Daclizumab Combined Therapy in patients with new onset Type 1 Diabetes. Diabetes Care 2010; 33:826-832. 8) Herold KC, Brooks-Worrell B, Palmer JP, Dosch HM, Peakman M, Gottlieb PA, Reijonen H, Arif S, Spain LM, Thompson C, Lachin JM, and The Type 1 Diabetes TrialNet Research Group [Skyler JS – Study Group Chairman]. Validity and Reproducibility of Measurement of Islet Autoreactivity by T-cell Assays in Subjects with Early Type 1 Diabetes. Diabetes 2009; 58:2588-2595. 9) Sosenko JM, Mahon J, Rafkin-Mervis L, Lachin JM, Krause-Steinrauf H, Krischer J, Cuthbertson D, Palmer JP, Thompson C, Greenbaum CJ, Skyler JS, and the Diabetes Prevention Trial-Type 1 Diabetes (DPT-1) and Type 1 Diabetes TrialNet Study Groups. A Comparison of the Baseline Metabolic Profiles between Diabetes Prevention Trial-Type 1 and TrialNet Natural History Study Participants. Pediatric Diabetes 2011; 12:85-90. 10) Sosenko JM, Skyler JS, Mahon J, Krischer JP, Beam CA, Boulware DC, Greenbaum CJ, Rafkin LE, Cowie C, Cuthbertson D, Palmer JP, and The TrialNet and Diabetes Prevention Trial-Type 1 Study Groups. Validation of the Diabetes Prevention Trial-Type 1 Risk Score (DPTRS) in the TrialNet Natural History Study. Diabetes Care 2011; 34: 1785-1787. 11) Vehik K, Cuthbertson D, Ruhling H, Schatz DA, Peakman M, Krischer JP, on behalf of the DPT-1 & TrialNet Study Groups. Long Term Outcome of Those Treated with Oral Insulin: DPT-1 Oral Insulin Trial. Diabetes Care 2011; 34: 1585-1590. 12) Orban T, Bundy B, Becker DJ, DiMeglio LA, Gitelman SE, Goland R, Gottlieb PA, Greenbaum CJ, Marks JB, Monzavi R, Moran A, Raskin P, Rodriguez H, Russell WE, Schatz D, Wherrett D, Wilson DM, Skyler JS, and and The Type 1 Diabetes TrialNet Abatacept Study Group. Co-Stimulation Modulation with Abatacept in Patients with Recent-Onset Type 1 Diabetes: A Randomised Double-Blind, Placebo-Controlled Trial. Lancet 2011; 378: 412-419. 13) Wherrett DK, Bundy B, Becker DJ, DiMeglio LA, Gitelman SE, Goland R, Gottlieb PA, Greenbaum CJ, Herold KC, Marks JB, Monzavi R, Moran A, Orban T, Raskin P, Rodriguez H, Russell WE, Schatz D, Wilson DM, Skyler JS, and and The Type 1 Diabetes TrialNet GAD Study Group. Antigen-Based Therapy with Glutamic Acid Decarboxylase (GAD) Vaccine in Patients with RecentOnset Type 1 Diabetes: A Randomised Double-Blind Trial. Lancet 2011; 378: 319-327. 14) Herold KC, Pescovitz MD, McGee PF, Krause-Steinrauf HJ, Spain LM, Bourcier K, Asare A, Liu Z, Lachin JM, Dosch HM, for the Type 1 Diabetes TrialNet Study Group [Skyler JS – Study Group Chairman]. Increased T-cell proliferative responses to islet antigens identify clinical responders to anti-CD20 monoclonal antibody (rituximab) therapy in Type 1 diabetes. Journal of Immunology 2011; 187:1998-2005. 15) Pescovitz MD, Torgerson TR, Ochs HD. Ocheltree E, Friedenberg-McGee P, Krause-Steinrauf HJ, Lachin JM, Canniff J, Weinberg A, Greenbaum CJ, Herold KC, Skyler JS, for the Type 1 Diabetes TrialNet Study Group. Effect of rituximab on human in vivo antibody immune responses. Journal of Allergy and Clinical Immunology 2011; 128:1295-1302. Jay S. Skyler Page 41 Curriculum Vitae 16) Vehik K, Beam CA, Mahon JL, Schatz DA, Haller MJ, Sosenko JM, Skyler JS, Krischer JP, for the TrialNet Natural History Study Group. Development of Autoantibodies in the TrialNet Natural History Study. Diabetes Care 2011; 34:1897-1901. 17) Yu L, Herold K, Lachin J, Bundy B, Pugliese A, Krischer J, Eisenbarth G, Pescovitz M, T1D Type 1 Diabetes TrialNet Anti-CD20 Study Group [Skyler JS – Study Group Chairman]. Rituximab Selectively Suppresses Specific Islet Antibodies. Diabetes 2011; 60:2560-2565. 18) Mahon JL, Beam CA, Marcovina SM, Boulware D, Palmer JP, Winter WE, Skyler JS, Krischer JP, for the TrialNet-Type 1 Diabetes Study Group. Comparison of two insulin assays for first-phase insulin release in type 1 diabetes prediction and prevention trials. Clinical Chemica Acta 2011; 412:2128-2131. 20) Sosenko JM, Skyler JS, Palmer JP, Krischer JP, Cuthbertson D, Yu L, Schatz D, Orban T, Eisenbarth GS, and The Diabetes Prevention Trial-1 and Type 1 Diabetes TrialNet Study Groups. Brief Report - A Longitudinal Study of GAD65 and ICA512 Autoantibodies during the Progression to Type 1 Diabetes in Diabetes Prevention Trial-Type 1 (DPT-1) Participants. Diabetes Care 2011; 34:2435-2437. 21) Lachin JM, McGee PL, Greenbaum CJ, Palmer JP, Pescovitz MD, Gottlieb PA, Skyler JS, for the Type 1 Diabetes TrialNet Study Group. Sample Size Requirements for Studies of Treatment Effects on Beta-Cell Function in Newly Diagnosed Type 1 Diabetes. PLoS One 2011; 6(11):e26471. Epub 2011 Nov 10. 22) Yu L, Boulware DC, Beam CA, Hutton JC, Wenzlau JM, Greenbaum CJ, Bingley PJ, Krischer JP, Sosenko JM, Skyler JS, Eisenbarth GS, Mahon JL, for the Type 1 Diabetes TrialNet Study Group. Zinc Transporter-8 Autoantibodies Improve Prediction of Type 1 Diabetes in Relatives Positive for the Standard Biochemical Autoantibodies. Diabetes Care 2012; 35:1213-1218. 23) Greenbaum CJ, Beam C, Boulware D, Gitelman SE, Gottlieb PA, Herold KC, Lachin JM, McGee P, Palmer JP, Krause-Steinrauf H, Skyler JS, Sosenko JM, on behalf of the Type 1 Diabetes TrialNet Study Group. Fall in C-peptide Over First Two Years from Diagnosis: Evidence of At Least Two Distinct Phases from Composite TrialNet Data. Diabetes 2012; 61: 2066-2073. 25) Sosenko JM, Skyler JS, Herold KC, Palmer JP, the Type 1 Diabetes TrialNet Study and Diabetes Prevention Trial-Type 1 Study Groups. The Metabolic Progression to Type 1 Diabetes as Indicated by Serial Oral Glucose Tolerance Testing in the Diabetes Prevention Trial-Type 1. Diabetes 2012; 61:1331-1337. 24) Sosenko JM, Skyler JS, Mahon J, Krischer JP, Beam CA, Boulware DC, Greenbaum CJ, Rafkin LE, Cowie C, Cuthbertson D, Palmer JP, the TrialNet and Diabetes Prevention Trial Type 1 Study Groups. The Application of the Diabetes Prevention Trial Risk Score (DPTRS) for Identifying a Pre-Clinical State of Type 1 Diabetes. Diabetes Care 2012; 35:1552-1555. 25) Vehik K, Cuthbertson D, Boulware D, Beam CA, Rodriguez H, Legault L, Hyytinen M, Rewers MJ, Schatz DA, Krischer JP, The TEDDY, TRIGR, Diabetes Prevention Trial-Type 1, and Type 1 Diabetes TrialNet Natural History Study Groups [Skyler JS – DPT-1 and TrialNet Study Groups Chairman]. Performance of HbA1c as an Early Diagnostic Indicator of Type 1 Diabetes in Children and Youth. Diabetes Care 2012; 35:1821-1825. 26) Long SA, Rieck M, Sanda S, Bollyky JB, Samuels PL, Goland R, Ahmann A, Rabinovitch A, Aggarwal S, Phippard D, Turka LA, Ehlers MR, Bianchine PJ, Boyle KD, Adah SA, Bluestone JA, Buckner JH, Greenbaum CJ; for Diabetes TrialNet and the Immune Tolerance Network [Skyler JS –TrialNet Study Group Chairman].. Rapamycin/IL-2 Combination Therapy in Patients with Type 1 Diabetes Augments Tregs yet Transiently Impairs β-Cell Function. Diabetes 2012; 61: 2340-2348. 27) Moran A, Bundy B, Becker DJ, DiMeglio LA, Gitelman SE, Goland R, Greenbaum CJ, Herold KC, Marks JB, Raskin P, Sanda S, Schatz D, Wherrett D, Wilson DM, Skyler JS, and the Type 1 Diabetes TrialNet Canakinumab Study Group; and Pickersgill L, de Koning E, Ziegler A-G, Böehm B, Badenhoop K, Schloot N, Bak JF, Pozzilli P, Mauricio D, Donath MY, Castaño L, Wägner A, Lervang HH, Perrild H, Mandrup-Poulsen T, on behalf of the AIDA Study Group. Interleukin-1 Antagonism in Type 1 Diabetes of Recent Onset: Two Multicenter, Randomized Double-Masked, Placebo-Controlled Trials. Lancet 2013; 381:1905-1915. 28) Loechelt BJ, Boulware D, Green M, Baden LR, Gottlieb P, Krause-Steinrauf H, Weinberg A; for the Type 1 Diabetes TrialNet Daclizumab/Mycophenolic Acid Study Group [Skyler JS – Study Group Chairman]. Epstein-Barr and Other Herpesvirus Infections in Patients With Early Onset Type 1 Diabetes Treated With Daclizumab and Mycophenolate Mofetil. Clinical Infectious Diseases 2013; 56:248-254. 29) Kroll JL, Beam C, Li S, Viscidi R, Dighero B, Cho A, Boulware D, Pescovitz M, Weinberg A; the Type 1 Diabetes TrialNet Anti CD-20 Study Group [Skyler JS – Study Group Chairman]. Reactivation of latent viruses in individuals receiving rituximab for new onset type 1 diabetes. Journal of Clinical Virology 2013; 57:115-119. 30) Orban T, Bundy B, Becker DJ, DiMeglio LA, Gitelman SE, Goland R, Gottlieb PA, Greenbaum CJ, Marks JB, Monzavi R, Moran A, Peakman M, Raskin P, Rodriguez H, Russell WE, Schatz D, Wherrett D, Wilson DM, Skyler JS, and and The Type 1 Diabetes Jay S. Skyler Page 42 Curriculum Vitae TrialNet Abatacept Study Group. Co-Stimulation Modulation with Abatacept in Patients with Recent-Onset Type 1 Diabetes: FollowUp One Year After Cessation of Treatment. Diabetes Care 2014; 37:1069-1075. 31) Pescovitz MD, Greenbaum CJ, Bundy BN, Becker DJ, Gitelman SE, Goland R, Gottlieb PA, Marks JB, McGee PF, Moran AM, Raskin P, Rodriguez H, Schatz DA, Wherrett D, Wilson DM, Skyler JS, and The Type 1 Diabetes TrialNet Anti-CD20 Study Group. B-Lymphocyte Depletion with Rituximab and Beta-Cell Function: Two-Year Results. Diabetes Care 2014; 37:453-459. 32) Diabetes Research in Children Network (DirecNet) Study Group, Type 1 Diabetes Trial Network [Skyler JS – TrialNet Study Group Chairman]. The Effects of Inpatient Hybrid Closed-Loop Therapy Initiated within 1 Week of Type 1 Diabetes Diagnosis. Diabetes Technology & Therapeutics 2013; 15:401-408. 33) Buckingham B, Beck RW, Ruedy KJ, Cheng P, Kollman C, Weinzimer SA, Dimeglio LA, Bremer AA, Slover R, Tamborlane WV; Diabetes Research in Children Network (DirecNet) and Type 1 Diabetes TrialNet Study Groups [Skyler JS – TrialNet Study Group Chairman]. Effectiveness of Early Intensive Therapy on β-Cell Preservation in Type 1 Diabetes. Diabetes Care 2013; 36:4030-4035. 34) Sosenko JM, Skyler JS, Palmer JP, Krischer JP, Yu L, Mahon J, Beam CA, Boulware DC; Rafkin L; Schatz D, Eisenbarth G, The Type 1 Diabetes TrialNet and the Diabetes Prevention Trial-Type 1 Study Groups. The Prediction of Type 1 Diabetes by Multiple Autoantibody Levels and Their Incorporation into an Autoantibody Risk Score in Relatives of Type 1 Diabetes Patients. Diabetes Care 2013; 36:2615-2620. 35) Sosenko JM, Skyler JS, Beam CA, Krischer JP, Greenbaum CG, Mahon J, Rafkin LE, Matheson D, Herold KC, Palmer JP, and The Diabetes Type 1 TrialNet and Diabetes Prevention Trial-Type 1 Study Groups. Acceleration of the Loss of the First-Phase Insulin Response during the Progression to Type 1 Diabetes in Diabetes Prevention Trial-Type 1 Participants. Diabetes 2013; 62:4179-4183. 36) Weinberg A, Boulware D, Dighero B, Orban T; Type 1 Diabetes TrialNet Abatacept Study Group [Skyler JS – Study Group Chairman]. Effect of abatacept on immunogenicity of vaccines in individuals with type 1 diabetes. Vaccine 2013; 31:4791-4794. 37) Krischer JP, the Type 1 Diabetes TrialNet Study Group [Skyler JS – Study Group Chairman]. The use of intermediate endpoints in the design of type 1 diabetes prevention trials. Diabetologia 2013; 56:1919-1924. 38) Sosenko JM, Skyler JS, Mahon J, Krischer JP, Greenbaum CG, Rafkin LE, Beam CA, Boulware DC, Matheson D, Cuthbertson D, Herold KC, Eisenbarth GS, Palmer JP, and The Diabetes Type 1 TrialNet and Diabetes Prevention Trial-Type 1 Study Groups. Use of the Diabetes Prevention Trial Risk Score (DPTRS) for Improving the Accuracy of the Risk Classification of Type 1 Diabetes. Diabetes Care 2014;37:979-984. 39) Orban T, Beam CA, Xu P, Moore K, Jiang Q, Deng J, Muller S, Gottlieb P, Spain L, Peakman M, and The Type 1 Diabetes TrialNet Abatacept Study Group [Skyler JS – TrialNet Study Group Chairman]. Reduction in CD4 Central Memory T-cell subset in Co-Stimulation Modulator Abatacept-Treated Patients with Recent-Onset Type 1 Diabetes is Associated with Slower C-Peptide Decline. Diabetes 2014; 63:3449-3457. 40) Loechelt B, Green M, Gottlieb P, Blumberg E, Weinberg A, Quinlan S, Baden L, Marks J, Type 1 Diabetes TrialNet [Skyler JS – TrialNet Study Group Chairman]. Screening and Monitoring of Infectious Complications when Immunosuppression Agents are Studied in the Treatment of Autoimmune Disorders. Journal of the Pediatric Infectious Disease Society 2014; on-line 6/26/14 41) Chase HP, Boulware D, Rodriguez H, Donaldson D, Chritton S, Rafkin LE, Krischer JP, Skyler JS, Clare-Salzler M, and the Type 1 Diabetes TrialNet Nutritional Intervention to Prevent (NIP) Type 1 Diabetes Study Group. Effect of Docosahexaenoic Acid (DHA) Supplementation on Infant Inflammatory Cytokine Levels in Infants at High Genetic Risk for Type 1 Diabetes. Pediatric Diabetes 2014; On-Line July 12 42) Beam CA, Gitelman SE, Palmer J, Type 1 Diabetes TrialNet Study Group [Skyler JS – TrialNet Study Group Chairman]. Recommendations for the Definition of Clinical Responder in Insulin Preservation Studies. Diabetes 2014; 63:3120-3127. 43) Sosenko JM, Skyler JS, Mahon J, Krischer JP, Greenbaum CJ, Rafkin LE, Beam CA, Boulware DC, Matheson D, Cuthbertson D, Herold KC, Eisenbarth GS, Palmer JP, and The Diabetes Type 1 TrialNet and Diabetes Prevention Trial-Type 1 Study Groups. Use of the Diabetes Prevention Trial-Type 1 Risk Score (DPTRS) for Improving the Accuracy of the Risk Classification of Type 1 Diabetes. Diabetes Care 2014; 37:979-984. 44) Loechelt B, Green M, Gottlieb P, Blumberg E, Weinberg A, Quinlan S, Baden L, Marks J, Type 1 Diabetes TrialNet [Skyler JS – TrialNet Study Group Chairman]. Screening and Monitoring of Infectious Complications when Immunosuppression Agents are Studied in the Treatment of Autoimmune Disorders. Journal of the Pediatric Infectious Disease Society, accepted 5/14/14 45) Max Andersen ML, Nielsen LB, Svensson J, Pörksen S, Hougaard P, Beam C, Greenbaum C, Becker D, Petersen JS, Hansen L, Mortensen HB, for the Type 1 Diabetes TrialNet [Skyler JS – TrialNet Study Group Chairman]. Disease progression among 446 Jay S. Skyler Page 43 Curriculum Vitae children with newly diagnosed type 1 diabetes located in Scandinavia, Europe, and North America during the last 27 yr. Pediatric Diabetes 2014; 15:345-354. 46) Beam CA, Gitelman SE, Palmer J, Type 1 Diabetes TrialNet Study Group [Skyler JS – TrialNet Study Group Chairman]. Recommendations for the Definition of Clinical Responder in Insulin Preservation Studies. Diabetes 2014; 63:3120-3127. 47) Sosenko JM, Skyler JS, DiMeglio LA, Beam CA, Krischer JP, Greenbaum CJ, Boulware D, Rafkin LE, Matheson D, Herold KC, Mahon J, Palmer JP; Type 1 Diabetes TrialNet Study Group; Diabetes Prevention Trial-Type 1 Study Group. A new approach for diagnosing type 1 diabetes in autoantibody-positive individuals based on prediction and natural history. Diabetes Care 2015; 38:271276. 48) Sosenko JM, Skyler JS, Beam CA, Boulware D, Mahon JL, Krischer JP, Greenbaum CJ, Rafkin LE, Matheson D, Herold KC, Palmer JP; and the Type 1 Diabetes TrialNet and Diabetes Prevention Trial–Type 1 Study Groups. The Development and Utility of a Novel Scale That Quantifies the Glycemic Progression Toward Type 1 Diabetes Over 6 Months. Diabetes Care 2015; 38:940-942. 49) Miao D, Steck AK, Zhang L, Guyer KM, Jiang L, Armstrong T, Muller SM, Krischer J, Rewers M, Yu L; Type 1 Diabetes TrialNet Study Group [Skyler JS – TrialNet Study Group Chairman]. Electrochemiluminescence assays for insulin and glutamic acid decarboxylase autoantibodies improve prediction of type 1 diabetes risk. Diabetes Technology and Therapeutics 2015; 17:119-127. 50) Usmani-Brown S, Lebastchi J, Steck AK, Beam C, Herold KC, Ledizet M for the Type 1 Diabetes TrialNet [Skyler JS – TrialNet Study Group Chairman]. Analysis of β-cell death in type 1 diabetes by droplet digital PCR. Endocrinology 2014; 155:3694-3698. 51) Herold KC, Usmani-Brown S, Ghazi T, Lebastchi J, Beam CA, Bellin MD, Ledizet M, Sosenko JM, Krischer JP, Palmer JP and the Type 1 Diabetes TrialNet [Skyler JS – TrialNet Study Group Chairman]. β Cell death and dysfunction during type 1 diabetes development in at-risk individuals. Journal of Clinical Investigation 2015; 125:1163-1173. 52) Bollyky JB, Xu P, Butte AJ, Wilson DM, Beam CA, Greenbaum CJ; Type 1 Diabetes TrialNet Study Group [Skyler JS – Study Group Chairman]. Heterogeneity in recent onset type 1 diabetes - a clinical trial perspective. Diabetes Metabolism Research and Reviews 2015; Feb 17. [Epub ahead of print]. 53) Sosenko JM, Skyler JS, Palmer JP, for The Diabetes Type 1 TrialNet and Diabetes Prevention Trial-Type 1 Study Groups. The Development, Validation, and Utility of the Diabetes Prevention Trial-Type 1 Risk Score (DPTRS). Current Diabetes Reports 2015; 15: Aug; 15(8):626 doi: 10.1007/s11892-015-0626-1. c. Inhaled Insulin Study Group References 1) Skyler JS, Cefalu WT, Kourides IA, Landschulz WH, Balagtas CC, Cheng S-L, Gelfand RA, for The Inhaled Insulin Phase II Study Group. Efficacy of Inhaled Human Insulin in Type 1 Diabetes Mellitus: A Randomised Proof-of-Concept Study. Lancet 2001; 357:331-335. 2) Cefalu WT, Skyler JS, Kourides IA, Landschulz WH, Balagtas CC, Cheng S-L, Gelfand RA, for The Inhaled Insulin Phase II Study Group. Inhaled Human Insulin Treatment of Patients with Type 2 Diabetes Mellitus. Annals of Internal Medicine 2001; 134:203-207. 3) Gerber RA, Cappelleri JC, Kourides IA, Gelfand RA for The Inhaled Insulin Phase II Study Group [Skyler JS – Study Group Participant]. Treatment satisfaction with inhaled insulin in patients with type 1 diabetes: a randomized controlled trial. Diabetes Care 2001; 24:1556-1559. 4) Cappelleri JC, Cefalu WT, Rosenstock J, Kourides IA, Gerber RA for The Inhaled Insulin Phase II Study Group [Skyler JS – Study Group Participant]. Treatment satisfaction in type 2 diabetes: a comparison between an inhaled insulin regimen and a subcutaneous insulin regimen. Clinical Therapeutics 2002; 24:552-564. 5) Weiss SR, Cheng SL, Kourides IA, Gelfand RA, Landschulz WH; Inhaled Insulin Phase II Study Group [Skyler JS – Study Group Participant]. Inhaled insulin provides improved glycemic control in patients with type 2 diabetes mellitus inadequately controlled with oral agents: a randomized controlled trial. Archives of Internal Medicine 2003;163:2277-2282. 6) Rosenstock J, Cappelleri JC, Bolinder B, Gerber RA, for the Inhaled Insulin Phase II Study Group [Skyler JS – Study Group Participant]. Patient satisfaction and glycemic control after 1 year with inhaled insulin (Exubera) in patients with type 1 or type 2 diabetes. Diabetes Care 2004; 27:1318-1323 7) Hollander PA, Blonde L, Rowe R, Mehta AE, Milburn JL, Hershon KS, Chiasson JL, Levin SR for the Exubera Phase III Study Group [Skyler JS – Study Group Participant]. Efficacy and Safety of Inhaled Insulin (Exubera) Compared With Subcutaneous Insulin Therapy in Patients With Type 2 Diabetes: Results of a 6-month, randomized, comparative trial. Diabetes Care 2004; 27: 2356-2362 Jay S. Skyler Page 44 Curriculum Vitae 8) Skyler JS, Weinstock R, Raskin P, Yale JF, Barrett E, Gerich JE, Gerstein H for The Inhaled Insulin Phase III Type 1 Diabetes Study Group. Use of inhaled insulin in a basal/bolus insulin regimen in patients with type 1 diabetes: a 6-month, randomized, comparative trial. Diabetes Care 2005; 28: 1630-1635 9) Rosenstock J, Zinman B, Murphy LJ, Clement SC, Moore P, Bowering CK, Hendler R, Lan SP, Cefalu WT for The Inhaled Insulin Phase III Type 2 Diabetes Study Group [Skyler JS – Study Group Participant]. Inhaled Insulin Improves Glycemic Control When Substituted for or Added to Oral Combination Therapy in Type 2 Diabetes. Annals of Internal Medicine 2005; 143:549-558. 10) Skyler JS, Jovanovic L, Klioze S, Reis J, Duggan W, for The Inhaled Insulin Type 1 Study Group. Two-year safety and efficacy of inhaled human insulin (Exubera) in adult patients with type 1 diabetes mellitus. Diabetes Care 2007; 30:579-585. 11) Skyler JS, Hollander PA, Jovanovic L, Klioze S, Krasner A, Riese RJ, Reis J, Schwartz P, Duggan W, for The Inhaled Human Insulin Type 1 Diabetes Study Group. Safety and efficacy of inhaled human insulin (Exubera) during discontinuation and readministration of therapy in adults with type 1 diabetes: a 3-year randomized controlled trial. Diabetes Research and Clinical Practice 2008; 82:238-246. 12) Cefalu WT, Bohannon NJ, Edwin Fineberg S, Teeter JG, Schwartz PF, Reis JM, Krasner AS [Skyler JS – Study Group Participant]. Assessment of long-term immunological and pulmonary safety of inhaled human insulin with up to 24 months of continuous therapy. Current Medical Research and Opinion 2008; 24:3073-3083. 2. BOOKS AND BOOK CHAPTERS a. BOOKS AND MONOGRAPHS 1) Skyler JS: Notes on Diabetes Mellitus. Health Care Systems, Inc., Durham, North Carolina, 1973. 2) Skyler JS (Editor): Recommended Standards for Camps for Children with Diabetes. American Diabetes Association, New York, 1976. 3) Skyler JS, Cahill GF (Editors): Diabetes Mellitus. Yorke Medical Books, New York, 1981 4) Skyler JS (Editor): Insulin Update 1982. Excerpta Medica, Princeton, N.J., 1982. 5) Schade DS, Santiago JV, Skyler JS, Rizza R: Intensive Insulin Therapy. Excerpta Medica, Princeton, N.J., 1983. 6) Schade DS, Santiago JV, Skyler JS, Rizza R: Insulinoterapia Intensiva. Jarpyo Editores, Madrid, 1984. 7) Rifkin H, Cahill GF, Colwell JA, DeFronzo RA, Holvey SM, Horton, ES, Lebovitz HE, Olefsky JM, Skyler JS (Editors): The Physician's Guide to Type II Diabetes (NIDDM) - Diagnosis and Treatment. American Diabetes Association, New York, 1984. 8) Lebovitz HE, Clark CM, DeFronzo RA, Gerich J, Kreisberg R, Lockwood D, Rosenbloom A, Skyler JS, Vinicor F, Zimmerman B (Editors): Physician's Guide to Non-Insulin-Dependent (Type II) Diabetes - Diagnosis and Treatment. Second Edition. American Diabetes Association, Alexandria, Virginia, 1988. 9) McCabe PM, Schneiderman N, Field T, Skyler JS (Editors): Stress, Coping, and Disease. Lawrence Erlbaum Associates, Inc., Publishers, Hillside, N.J., 1991. 10) Skyler JS: Current Concepts: Insulin Treatment of Type I Diabetes Mellitus. The Upjohn Company, Kalamazoo, Michigan, 1991. 11) Bode BW, Davidson PC, Steed RD. Skyler JS (Editor). DiabetesDek - Professional Edition. Infodek, Inc., Atlanta, Georgia, 1993. WHO Study Group on Prevention of Diabetes Mellitus [Akerblom H, Alberti KGMM, Baba S, Bennett PH, Dedov I, Keen H, Klein R, Nerup J, XiaoPrevention of Diabetes Mellitus - WHO Technical Report Series #844. World Health Organization, Geneva, 1994. 12) Ren P, Puchulu FE, Skyler J, Steiner G, Swai A, Zimmet P, Assal J-P]. 13) Farkas-Hirsch, RM, Brackenridge BP, Lorenz R, Lorenzi GM, Schreiner B, Skyler JS, Strowig SM, White NH, Whitehouse FW, Young-Hyman D (Editors). Intensive Diabetes Management. American Diabetes Association, Alexandria, Virginia, 1995. 14) Skyler JS (Editor): Medical Management of Type 1 Diabetes Mellitus. Third Edition. Alexandria, Va., American Diabetes Association, 1998. Jay S. Skyler Page 45 Curriculum Vitae 15) Skyler JS (Editor): Atlas of Diabetes. Second Edition. Philadelphia, Lippincott Williams & Wilkins, 2002. 16) Raz I, Skyler JS, Shafrir E (Editors): Diabetes: From Research to Diagnosis and Treatment. London, Martin Dunitz, 2003. 17) Bode BW, Davidson PC, Steed RD, Robertson DG. Skyler JS (Editor). DiabetesDek - Professional Edition. How to Control & Manage Diabetes Mellitus. American Diabetes Association, Alexandria, Virginia, 2004. 18) Skyler JS (Editor): Atlas of Diabetes. Third Edition. Philadelphia, Lippincott Williams & Wilkins, 2006. 19) Skyler JS (Editor): Atlas of Diabetes. Third Edition, Second (Revised and Expanded) Printing. Philadelphia, Lippincott Williams & Wilkins, 2008. 20) Skyler JS (Editor): Atlas of Type 2 Diabetes. Philadelphia, Current Medical Group, 2009. 21) Skyler JS (Editor): Atlas of Diabetes. Fourth Edition. New York, Springer, 2012. b. BOOK CHAPTERS 1) Field RA, Skyler JS: Nonglucose Melliturias. In: Ellenberg M, Rifkin H (Editors): Diabetes Mellitus: Theory and Practice. McGraw-Hill, New York, 1970, pages 546-563 2) Skyler JS, Ellis GJ, Delcher HK: The Value of Summer Camps. In: Laron Z (Editor): Diabetes in Juveniles: Modern Problems in Pediatrics (S. Karger, Basle) 1975; 12:382-384 3) Skyler JS: Nutritional Management of Diabetes Mellitus. In: Katzen HM, Mahler RJ (Editors): Advances in Modern Nutrition, Volume 2. Hemisphere Publishing, Washington, 1978, pages 645-698 4) Skyler JS: Diabetes in Adolescence - The Forgotten Years. In: Podolsky S (Editor), Clinical Diabetes Mellitus - Modern Management, Appleton-Century-Crofts, New York, 1980, pages 463-479 5) Skyler JS, Mintz DH, O'Sullivan MJ: Management of Diabetes and Pregnancy. In: Rifkin H, Raskin P (Editors): Diabetes Mellitus - Diagnosis and Treatment (5th Edition). American Diabetes Association, New York, 1980, pages 161-177 6) Skyler JS: Living with Complications of Diabetes. In: Hamburg BA, Lipsett LF, Inoff GE, Drash AL (Editors): Behavioral and Psychosocial Issues in Diabetes: Proceedings of the National Conference. Government Printing Office, Washington, NIH Publication No. 80-1993, 1980, pages 167-181 7) Skyler JS: Disorders of Galactose, Fructose, and Pentose Metabolism. In: Ellenberg M, Rifkin H (Editors): Diabetes Mellitus: Theory and Practice, Third Edition. Medical Examination Publishing Co., New Hyde Park, N.Y., 1983, pages 1021-1036 8) Barkin JS, Skyler JS: Diabetes and the Gastrointestinal System. In: Ellenberg M, Rifkin H (Editors): Diabetes Mellitus: Theory and Practice, Third Edition. Medical Examination Publishing Co., New Hyde Park, N.Y., 1983, pages 863-877 9) Skyler JS: Nondiabetic Melliturias. In: Brodoff BN, Bleicher SJ (Editors): Diabetes Mellitus and Obesity. Williams & Wilkins, Baltimore, 1982, pages 407-413 10) Alejandro R, Skyler JS: The Diagnosis of Diabetes Mellitus. In: Brodoff BN, Bleicher SJ (Editors): Diabetes Mellitus and Obesity. Williams & Wilkins, Baltimore, 1982, pages 400-406 11) Barkin JS, Skyler JS: The Gastrointestinal System in Diabetes. In: Brodoff BN, Bleicher SJ (Editors): Diabetes Mellitus and Obesity. Williams & Wilkins, Baltimore, 1982, pages 697-701 12) Skyler JS: Dietary Management of Diabetes Mellitus. In: Peterson CM (Editor): Diabetes Management in the 80's: The Role of Home Blood Glucose Monitoring and New Insulin Delivery Systems. Prager Scientific, New York, 1982, pages 126-151 13) Citrin WS, Kleiman GA, Skyler JS: Emotions: A Critical Factor in Diabetic Control. In: Davidson MB (Editor): Diabetes Mellitus: Diagnosis and Treatment. John Wiley and Sons, New York, 1981, pages 400-419 Jay S. Skyler Page 46 Curriculum Vitae 14) Skyler JS, Galloway JA, Chance RE: Human Insulin Produced by Recombinant DNA Technology. In: Skyler JS, Cahill GF (Editors): Diabetes Mellitus. Yorke Medical Books, New York, 1981, pages 146-151 15) Skyler JS, Reeves ML, Seigler DE, Ryan EA: Self-Monitoring of Blood Glucose and Intensive Coventional Therapy: Comparison with Continuous Subcutaneous Insulin Infusion in Insulin-Dependent Diabetes Mellitus. In: Brunetti P, Alberti KGMM, Albisser AM, Hepp KD, Massi-Benedetti M (Editors): Artificial Systems for Insulin Delivery. Raven Press, New York, 1983, pages 329-338 16) Skyler JS, Miller NE, O'Sullivan MJ, Reeves ML, Ryan EA, Seigler DE, Skyler DL, Zigo MA: The Use of Insulin in InsulinDependent Diabetes Mellitus. In: Skyler JS (Editor): Insulin Update 1982. Excerpta Medica, Princeton, 1982, pages 125-156 17) Skyler JS: On the Pathogenesis and Treatment of Non-Insulin-Dependent Diabetes Mellitus. In: Skyler JS (Editor): Insulin Update 1982. Excerpta Medica, Princeton, 1982, pages 247-259 18) Ryan EA, O'Sullivan MJ, Skyler JS, Mintz DH: Glucose Control During Labor and Delivery. In: Skyler JS (Editor): Insulin Update 1982. Excerpta Medica, Princeton, 1982, pages 290-294 19) Skyler JS: Problems with Oral Agents. In: Krall LP (Editor): World Book of Diabetes in Practice. Excerpta Medica, Amsterdam, 1982, pages 52-54 20) Skyler JS, Chance RE, Horwitz D, Weis-Fogh O, Hansen B, Levin M, Chiu Y: Report of the Consensus-Forming Session on Insulins. In: Gueriguian J, Bransome ED, Outschoorn AS (Editors): Hormone Drugs. United States Pharmacopeial Convention, Rockville, Maryland, 1983, pages 254-281 21) Skyler JS: Diabetes and Pregnancy - The 1980's and Beyond. In: Sutherland H, Stowers J (Editors): Carbohydrate Metabolism in Pregnancy and the Newborn 1983. Churchill Livingstone, Edinburgh, 1984, pages 226-234 22) Skyler JS, Reeves ML, Seigler DE: Intensive Insulin Therapy. In: Sakamoto N, Min HK, Baba S (Editors): Current Topics in Clinical and Experimental Aspects of Diabetes Mellitus. Excerpta Medica, Amsterdam, 1984, pages 438-450 23) Skyler JS, Reeves ML: Intensive Treatment of Type I Diabetes Mellitus. In: Olefsky JM, Sherwin RS (Editors): Diabetes Mellitus: Management and Complications. Churchill Livingstone, New York, 1985, pages 31-79 24) Citrin WS, LaGreca AM, Skyler JS: Group Intervention in Type I Diabetes Mellitus. In: Ahmed PI, Ahmed N (Editors): Coping with Juvenile Diabetes. Charles C Thomas, Springfield, 1985, pages 181-204 25) Skyler JS: The Etiology, Pathogenesis and Therapy of Type I Diabetes Mellitus. In: Lavin N (Editor): Manual of Endocrinology and Metabolism. Little Brown and Company, Boston, 1986, pages 565-572 26) Skyler JS: Diabetes in 2021 - One Hundred Years After Insulin. In: Baba S, Gould M, Zimmet P (Editors): Diabetes - Recent Knowledge on Aetiology, Complications and Treatment. Academic Press, Sydney, 1984, pages 237-252 27) Skyler JS: Self-monitoring of Blood Glucose - 1987. In: Consensus Development Conference on Self-Blood Glucose Monitoring. American Diabetes Association, Alexandria, Virginia, 1986, pages 12-16 28) Skyler JS: Insulin-Dependent Diabetes Mellitus. In: Kohler PO (Editor): Clinical Endocrinology. John Wiley and Sons, New York, 1986, pages 491-573 29) Skyler JS, O'Sullivan, MJ: Diabetes and Pregnancy. In: Kohler PO (Editor): Clinical Endocrinology. John Wiley and Sons, New York, 1986, pages 603-622 30) Citrin WS, Kleiman GA, Skyler JS: Emotions: A Critical Factor in Diabetic Control. In: Davidson MB (Editor): Diabetes Mellitus: Diagnosis and Treatment, Second Edition, John Wiley and Sons, New York, 1986, pages 487-510 31) Skyler JS: Forward. In: Jackson RL, Guthrie RA (Editors): The Physiological Management of Diabetes in Children. Medical Examination Publishing Co., New York, 1986, pages xiii-xvi 32) Skyler JS: Self-monitoring of Blood Glucose. In: Reeves-Ellington B (Editor): Blood Glucose Monitoring: For the Phases of Your Life, Health Education Technologies, New York, 1986, pages 18-24 33) Skyler JS: Non-insulin-dependent Diabetes Mellitus: A Clinical Strategy. In: Clinical Diabetes Reviews Volume 1. American Diabetes Association, Alexandria, Virginia, 1987, pages 65-77 34) Ryan EA, Enns L, O'Sullivan MJ, Skyler JS: Insulin Action in Pregnancy. In: Goren HJ, Hollenberg MD, Roncari DAK (Editors): Insulin Action in Diabetes, Raven Press, New York, 1988, pages 191-201 Jay S. Skyler Page 47 Curriculum Vitae 35) Skyler JS: Monitoring of Diabetes. In: Galloway JA, Potvin JH, Shuman CR (Editors): Diabetes Mellitus. Eli Lilly and Company, Indianapolis, 1988, pages 159-173 36) Skyler JS: Methods for the Study of Carbohydrate Metabolism. In: Schneiderman N, Kaufmann PG, Weiss SM (Editors): Handbook of Research Methods in Cardiovascular Behavioral Medicine, Plenum Press, New York, 1989, pages 145-166 37) Seigler DE, Olsson GM, Skyler JS: Patient Self-Design of a Meal Plan: An Experiential Approach to Diabetes Nutritional Management. In: Challenges in Diabetes Management/Milestone in Monitoring: Colloquium Proceedings, Health Education Technologies, New York, 1988, pages 18-22 38) Drexler AJ, Hunt JA, Skyler JS, Yale JF, Alojado NC, Olsson GM, Robertson C, Seigler DE: Multicenter Study to Determine the Accuracy and Precision of the One Touch System When Used by Patients and Technicians. In: Challenges in Diabetes Management/Milestone in Monitoring: Colloquium Proceedings, Health Education Technologies, New York, 1988, pages 50-54 39) Skyler JS: Diabetes and Pregnancy: Consensus and Controversy. In: Sutherland HW, Stowers JM, Pearson DWM (Editors): Carbohydrate Metabolism in Pregnancy and the Newborn IV. Springer-Verlag, London, 1989, pages 363-372 40) Skyler JS: Relationship of Metabolic Control of Diabetes Mellitus to Chronic Complications. In: Rifkin H, Porte D (Editors): Ellenberg & Rifkin's Diabetes Mellitus: Theory and Practice, Fourth Edition. Elsevier Science Publishing, New York, 1990, pages 856-868 41) Hartford JD, Barkin JS, Skyler JS: Diabetes and the Gastrointestinal System. In: Rifkin H, Porte D (Editors): Ellenberg & Rifkin's Diabetes Mellitus: Theory and Practice, Fourth Edition. Elsevier Science Publishing, New York, 1990, pages 824-837 42) Skyler JS: Issues, Controversies, and Directions in Diabetes Care. In: Larkins RG, Zimmet PZ, Chisholm DJ (Editors): Diabetes 1988. Excerpta Medica, Amsterdam, 1989, pages 793-801 43) Skyler JS: Continuous Subcutaneous Insulin Infusion [CSII] With External Devices: Current Status. In: Ensminger WD, Selam JL (Editors): Update in Drug Delivery Systems. Futura Publishing, Mount Kisco, N.Y., 1989, pages 163-183 44) Skyler JS, Fili MD: Intensive Therapy of Type I Diabetes: 1989. In: Sakamoto N, Alberti KGMM, Hotta N (Editors): Current Status of Prevention and Treatment of Diabetic Complications. Excerpta Medica, Amsterdam, 1990, pages 235-242 45) LaGreca AM, Skyler JS: Psychosocial Issues in IDDM: A Multivariate Framework. In: McCabe PM, Schneiderman N, Field T, Skyler JS (Editors): Stress, Coping, and Disease. Lawrence Erlbaum Associates, Hillside, N.J., 1991, pages 169-190 46) LaGreca AM, Rappoport WS, Skyler JS: Emotions: A Critical Factor in Diabetes Control. In: Davidson Mayer B (Editor): Diabetes Mellitus: Diagnosis and Treatment, Third Edition, Churchill Livingstone, New York, 1991, pages 403-417. 47) O'Sullivan MJ, Skyler JS, Reimer K, Abu Hamad A: Diabetes and Pregnancy. In: Gleicher N (Editor): Principles of Medical Therapy In Pregnancy, Second Edition. Appleton & Lange, Norwalk, Connecticut, 1992, pages 357-378 48) Skyler JS: Insulin Treatment. In: Lebovitz HE (Editor): Therapy for Diabetes Mellitus & Related Disorders. American Diabetes Association, Alexandria, Virginia, 1991, pages 127-137 49) Marks JB, Skyler JS: Acute Complications of Diabetes: Diabetic Ketoacidosis and Hyperosmolar Hyperglycemic Nonketotic Coma. In: Hurst JW (Editor): Medicine for the Practicing Physician, Third Edition. Butterworth-Heineman, Boston, 1992, pages 592-596. 50) Skyler JS, Marks JB: Type I (Insulin-Dependent) Diabetes Mellitus. In: Hurst JW (Editor): Medicine for the Practicing Physician, Third Edition. Butterworth-Heineman, Boston, 1992, pages 582-588. 51) Skyler JS, Marks JB, Thompson NE, Fili MD, Schneiderman N: Insulin Sensitivity and Blood Pressure. In: Schneiderman N, McCabe PM, Baum A (Editors): Stress and Disease Processes: Perspectives in Behavioral Medicine. Lawrence Erlbaum Associates, Inc., Publishers, Hillside, N.J., 1992, pages 197-223. 52) Skyler JS, Donahue RP, Marks JB, Thompson NE, Schneiderman N: Insulin: A Determinant of Blood Pressure? In: Johnson E, Gentry WD, Julius S (Editors): Personality, Elevated Blood Pressure, and Essential Hypertension. Hemisphere Taylor & Francis, Washington, 1992, pages 257-281. 53) Skyler JS: Complicaciones de la Diabetes en los Noventas. In: Rull JA, Zorrilla E, Jadzinsky M, Santiago JV (Editors): Complicaciones de la Diabetes Mellitus. Interamericana McGraw Hill, Mexico City, 1992, pages 31-44. Jay S. Skyler Page 48 Curriculum Vitae 54) Skyler JS: Insulin Dependent (Type I) Diabetes Mellitus. In: Kreisberg R (Editor): Diabetes Mellitus: Diagnosis & Management. National Health Laboratories, La Jolla, 1992, pages 4-15. 55) Antoni MH, Schneiderman N, LaPerriere A, O'Sullivan MJ, Marks J, Efantis J, Skyler J, Fletcher MA: Mothers with AIDS. In: Ahmed PI (Editor): Living and Dying with AIDS. Plenum Press, New York, 1992, pages 47-85. 56) Skyler JS: Forward. In: Current Trends in Diabetes Management: A Guide for the Diabetes Professional, Third Edition. Diabetes Treatment Centers of America, Inc., Nashville, 1992, pages iii-v. 57) Skyler JS: Etiology, Pathogenesis and Therapy of Type I Diabetes Mellitus. In: Lavin N (Editor): Manual of Endocrinology and Metabolism, Second Edition. Little Brown and Company, Boston, 1993, pages 519-527. 58) Skyler JS: Insulin Treatment. In: Lebovitz HE (Editor): Therapy for Diabetes Mellitus & Related Disorders, Second Edition. American Diabetes Association, Alexandria, Virginia, 1994, pages 131-141. 59) LaGreca AM, Skyler JS: Psychological Management of Diabetes. In: Kelnar CJH (Editor): Childhood Diabetes. Chapman and Hall, London, 1995, pages 295-309. 60) Schneiderman N, Skyler JS: Insulin Metabolism, Sympathetic Nervous System Regulation, and Coronary Heart Disease Prevention. In: Orth-Gomer K, Schneiderman N (Editors): Behavioral Medicine Approaches to Cardiovascular Disease Prevention. Lawrence Erlbaum Associates, Inc., Publishers, Hillside NJ, 1996, pages 105-133. 61) Skyler JS: Relationship of Glycemic Control to Diabetic Complications. In: Porte D, Sherwin R (Editors): Ellenberg & Rifkin's Diabetes Mellitus: Theory and Practice, Fifth Edition. Appleton and Lange, Norwalk, CT, 1997, pages 1235-1254. 62) Skyler JS, Marks JB, O’Sullivan MJ: Prevention and Immunotherapy. In: Reece EA, Coustan DR (Editors): Diabetes Mellitus in Pregnancy, Second Edition. Churchill Livingstone, New York, 1995, pages 27-34. 63) Skyler JS: Multiple-Component Insulin Regimens. In: Farkas-Hirsch, RM (Editor). Intensive Diabetes Management. American Diabetes Association, Alexandria, Virginia, 1995, pages 51-64. 64) Skyler JS, Marks JB: Future Approaches to Prevention. In: Palmer JP (Editors): Prediction, Prevention, and Genetic Counseling in IDDM. John Wiley and Sons, Sussex, England, 1996, pages 369-389. 65) Marks JB, Skyler JS: Acute Complications of Diabetes: Diabetic Ketoacidosis and Hyperosmolar Hyperglycemic Nonketotic Coma. In: Hurst JW (Editor): Medicine for the Practicing Physician, Fourth Edition. Butterworth-Heineman, Boston, 1996, pages 639-643. 66) Skyler JS, Marks JB: Type I (Insulin-Dependent) Diabetes Mellitus. In: Hurst JW (Editor): Medicine for the Practicing Physician, Fourth Edition. Butterworth-Heineman, Boston, 1996, pages 628-635. 67) Skyler JS, Marks JB: Immune Intervention. In: LeRoith D, Taylor SI, Olefsky JM (Editors): Diabetes Mellitus: A Fundamental and Clinical Text. Lippincott-Raven, Philadelphia, 1996, pages 402-408. 68) Skyler JS: Diabetes Mellitus, Types I and II. In: Kelley WN (Editor). Textbook of Internal Medicine, Third Edition. Lippincott-Raven, Philadelphia, 1997, pages 2238-2252. 69) Skyler JS: Approach to Hyperglycemia in the Patient with Diabetes Mellitus. In: Kelley WN (Editor). Textbook of Internal Medicine, Third Edition. Lippincott-Raven, Philadelphia, 1997, pages 2155-2165. 70) Schneiderman N, Gellman M, Peckerman A, Hurwitz B, Saab P, Llabre M, Ironson G, Durel L, Skyler J, McCabre P: Cardiovascular Reactivity as an Indicator of Risk for Future Hypertension. In: In P. M. McCabe, N. Schneiderman, T. Field, & A. R. Wellens (Editors), Stress, Coping, and Cardiovascular Disease. Lawrence Erlbaum Associates, Inc., Publishers, Mahwah, NJ, 2000, pages 181-202. 71) Skyler JS: Insulin Therapy in Type 1 Diabetes Mellitus. In: DeFronzo RA (Editor): Current Therapy of Diabetes Mellitus. Mosby, St. Louis, 1998, pages 36-49. 72) Skyler JS: Monitoring of Type 1 Diabetes Mellitus. In: DeFronzo RA (Editor): Current Therapy of Diabetes Mellitus. Mosby, St. Louis, 1998, pages 50-54. 73) Skyler JS: Insulin Therapy in Type 2 Diabetes Mellitus. In: DeFronzo RA (Editor): Current Therapy of Diabetes Mellitus. Mosby, St. Louis, 1998, pages 108-116. Jay S. Skyler Page 49 Curriculum Vitae 74) Skyler JS, Cohen M: Self-Monitoring of Blood Glucose. In: Alberti KGMM, DeFronzo RA, Keen H, Zimmet PZ (Editors): International Textbook of Diabetes Mellitus, Second Edition. John Wiley and Sons, Sussex, England, 1997, pages 1031-1046. 75) Skyler JS: Insulin Treatment. In: Lebovitz HE (Editor): Therapy for Diabetes Mellitus & Related Disorders, Third Edition. American Diabetes Association, Alexandria, Virginia, 1998, pages 186-203. 76) Skyler JS: Multiple-Component Insulin Regimens. In: Farkas-Hirsch, RM (Editor). Intensive Diabetes Management, Second Edition. American Diabetes Association, Alexandria, Virginia, 1998, pages 73-98. 77) Marks JB, Skyler JS: The Liver and The Endocrine System. In: Schiff ER, Sorrell MF, Maddrey WC (Editors). Schiff's Diseases of the Liver, Eighth Edition. Lippincott-Raven, Philadelphia, 1999, pages 477-488. 78) Pugliese A, Skyler JS. Type 1 Diabetes Pathogenesis: Overview and Genetics. In: Turtle JR, Kaneko T, Osato S (Editors). Diabetes in the New Millennium. The Endocrinology & Diabetes Research Foundation of the University of Sydney, Sydney, Australia, 1999, pages 119-130. 79) Skyler JS. Medical Management of Diabetic Retinopathy. In: Flynn HW, Smiddy WE (Editors). Diabetes and Ocular Disease – Past, Present, & Future Therapies. Ophthalmology Monographs 14, Foundation of the American Academy of Ophthalmology, San Francisco, 2000, pages 181-201. 80) Skyler JS: Diabetes Mellitus: Old Assumptions and New Realities. In: Bowker J, Pfeifer M (Editors). The Diabetic Foot, Sixth Edition. Mosby, St. Louis, 2000, pages 3-12.. 81) Skyler JS, Marks JB: Immune Intervention. In: LeRoith D, Taylor SI, Olefsky JM (Editors): Diabetes Mellitus: A Fundamental and Clinical Text. Second Edition. Lippincott-Williams & Wilkins, Philadelphia, 2000, pages 500-506. 82) Skyler JS, Hirsch IB: Diabetes Mellitus. In: Noble J (Editor): Textbook of Primary Care Medicine, Third Edition. Mosby, St. Louis, 2001, pages 821-842. 83) Skyler JS: Diabetes Mellitus, Types I and II. In: Humes HD (Editor). Kelley’s Textbook of Internal Medicine, Fourth Edition. Lippincott-Williams & Wilkins, Philadelphia, 2000, pages 2751-2769. 84) Skyler JS: Approach to Hyperglycemia in the Patient with Diabetes Mellitus. In: Humes HD (Editor). Kelley’s Textbook of Internal Medicine, Fourth Edition. Lippincott-Williams & Wilkins, Philadelphia, 2000, pages 2635-2648. 85) Skyler JS, Pugliese A, Bernal C, Marks JB. Prevention of Type 1 Diabetes Mellitus. In: Ekoe JM, Zimmet P, Williams R (editors). The Epidemiology of Diabetes Mellitus: An International Perspective. John Wiley and Sons, Chichester, England, 2001, pages 31-40. 86) Skyler JS: Etiology, Pathogenesis and Therapy of Type I Diabetes Mellitus. In: Lavin N (Editor): Manual of Endocrinology and Metabolism, Third Edition. Lippincott-Williams & Wilkins, Philadelphia, 2002, pages 575-583. 87) Skyler JS: Relationship of Glycemic Control to Diabetic Complications. In: Porte D, Sherwin R, Baron A (Editors): Ellenberg & Rifkin's Diabetes Mellitus: Theory and Practice, Sixth Edition. McGraw-Hill, New York, 2003, pages 905-926. 88) Skyler JS: Prevention of Type 1 Diabetes. In: Williams R, Herman W, Kinmouth AL, Wareham NJ (Editors). The Evidence Base for Diabetes Care. John Wiley and Sons, West Sussex, England, 2002, pages 45-68. 89) Marks JB, Skyler JS: The Liver and The Endocrine System. In: Schiff ER, Sorrell MF, Maddrey WC (Editors). Schiff's Diseases of the Liver, Ninth Edition. Lippincott-Williams & Wilkins, Philadelphia, 2003, pages 529-542. 90) Skyler JS: Immunotherapy for Interdicting the Type 1 Diabetes Disease Process. In: Pickup J, Williams G (Editors), Textbook of Diabetes, Third edition, Blackwell Publishing Ltd., Oxford, UK, 2003, pages 74-1 to 74-12. 91) Skyler JS: Diabetes Mellitus: Pathogenesis and Natural History. In: Gruessner RWG , Sutherland DER (Editors), Transplantation of the Pancreas, Springer, 2004, pages 11-27. 92) Skyler JS: A View of the Future. In: Raz I, Skyler JS, Shafrir E (Editors): Diabetes: From Research to Diagnosis and Treatment. London, Martin Dunitz, 2003, pages 547-558. 93) Skyler JS, Marks JB: Immune Intervention. In: LeRoith D, Taylor SI, Olefsky JM (Editors): Diabetes Mellitus: A Fundamental and Clinical Text. Third Edition. Lippincott-Williams & Wilkins, Philadelphia, 2004, pages 701-709. Jay S. Skyler Page 50 Curriculum Vitae 94) Skyler JS: Insulin Treatment. In: Lebovitz HE (Editor): Therapy for Diabetes Mellitus & Related Disorders, Fourth Edition. American Diabetes Association, Alexandria, Virginia, 2004, pages 207-223. 95) Skyler JS: Self-Monitoring of Blood Glucose. In: DeFronzo RA, Ferrannini E, Keen H, Zimmet P (Editors): International Textbook of Diabetes Mellitus, Third Edition. John Wiley and Sons, Sussex, England, 2004, pages 1672-1683. 96) Skyler JS: Relationship of Glycemic Control to Diabetic Complications. In: Inzucchi SE (Editor): The Diabetes Mellitus Manual (A Primary Care Companion to Ellenberg & Rifkin's Sixth Edition). McGraw-Hill, New York, 2005, pages 290-302. 97) Lopez-Sandrin M, Skyler JS. Prevention of Diabetes Mellitus. In: Dulmus CN, Rapp-Paglicci LA (Editors): Handbook of Preventive Interventions for Adults. John Wiley and Sons, Hoboken NJ, 2005, pages 187-213. 98) Atkinson MA, Skyler JS. Type 1 Diabetes. In: Skyler JS (Editor): Atlas of Diabetes. Third Edition. Lippincott Williams & Wilkins, Philadelphia, 2006, pages 57-76. 99) Hirsch IB, Skyler JS. Management of Type 1 Diabetes. In: Skyler JS (Editor): Atlas of Diabetes. Third Edition. Lippincott Williams & Wilkins, Philadelphia, 2006, pages 77-88. 100) Hirsch IB, Skyler JS. The Management of Type 1 Diabetes. In: Goldfine I, Rushakoff RJ (Section Editors). Endotext.com. 2006. (http://www.endotext.com/diabetes/diabetes20/diabetesframe20.htm) 101) Skyler JS. Diabetes Mellitus: Old Assumptions and New Realities. In: Bowker J, Pfeifer M (Editors). The Diabetic Foot, Seventh Edition. Mosby, St. Louis, 2008, pages 23-32. 102) Skyler JS. Newer Diabetes Medications. In: Skyler JS (Editor): Atlas of Diabetes. Third Edition, Second Printing. Lippincott Williams & Wilkins, Philadelphia, 2008, pages 275-302. 103) Skyler JS: Etiology, Pathogenesis and Therapy of Type I Diabetes Mellitus. In: Lavin N (Editor): Manual of Endocrinology and Metabolism, Fourth Edition. Lippincott-Williams & Wilkins, Philadelphia, 2009, pages 589-597. 104) Skyler JS. Medical Management of the Diabetic Patient. In: Scott IU, Flynn HW, Smiddy WE. Diabetes and Ocular Disease Past, Present, & Future Therapies, Second Edition (Ophthalmology Monographs 14). Oxford University Press, New York, 2009, pages 353-371. 105) Skyler JS. Insulin Treatment. In: Lebovitz HE (Editor): Therapy for Diabetes Mellitus & Related Disorders, Fifth Edition. American Diabetes Association, Alexandria, Virginia, 2009, pages 273-289. 106) Skyler JS. Prevention of Type 1 Diabetes. In: Herman WH, Kinmonth AL, Wareham NJ, Williams R (Editors): The Evidence Base for Diabetes Care, Second Edition. Wiley-Blackwell, Chichester UK, 2010, pages 31-48. 107) Skyler JS. Immunomodulation (Immunotherapy) for Type 1 Diabetes Mellitus. In: Phillip M, Battelino T (Editors). ATTD 2009 Year Book - Advanced Technologies and Treatment for Diabetes. Wiley-Blackwell, Chichester UK, 2010, pages 168-182. 108) Skyler JS. Diabetes Management and CVD Risk Reduction. In: Eckel RH (Editor). Metabolic Risk for Cardiovascular Disease. American Heart Association Clinical Series. Wiley-Blackwell, Chichester UK, 2011, pages 198-219. 109) Skyler JS. Immune Intervention for Type 1 Diabetes Mellitus. In: Phillip M, Battelino T (Editors). ATTD 2010 Year Book Advanced Technologies and Treatment for Diabetes. Wiley-Blackwell, Chichester UK, 2011, pages 176-204. 110) Atkinson MA, Skyler JS. Type 1 Diabetes. In: Skyler JS (Editor): Atlas of Diabetes. Fourth Edition. Springer, New York, 2012, pages 65-94. 111) Hirsch IB, Skyler JS. Management of Type 1 Diabetes. In: Skyler JS (Editor): Atlas of Diabetes. Fourth Edition. Springer, New York, 2012, pages 95-113. 112) Skyler JS. Newer Diabetes Medications. In: Skyler JS (Editor): Atlas of Diabetes. Fourth Edition. Springer, New York, 2012, pages 375-419. 113) Skyler JS. Type 1 Diabetes Mellitus: Immune Intervention. In: Phillip M, Battelino T (Editors). ATTD 2011 Year Book Advanced Technologies and Treatment for Diabetes. Wiley-Blackwell, Chichester UK, 2012, pages 157-173. 114) Garg SK, Skyler JS. New Medications for the Treatment of Diabetes. In: Phillip M, Battelino T (Editors). ATTD 2011 Year Book - Advanced Technologies and Treatment for Diabetes. Wiley-Blackwell, Chichester UK, 2012, pages 243-270. Jay S. Skyler Page 51 Curriculum Vitae 115) Skyler JS. Immune Intervention in Type 1 Diabetes. In: Vora J, Buse J (Editors). Evidence-Based Management of Diabetes. Tfm Publishing, Shrewsbury UK, 2012, pages 187-210. 116) Hirsch IB, Skyler JS: The management of type 1 diabetes. Endotext.org. (http://www.endotext.com/diabetes/diabetes20/diabetesframe20.htm) 117) Skyler JS. The Year in Immune Intervention for Type 1 Diabetes. In: Phillip M, Battelino T (Editors). ATTD 2012 Year Book - Advanced Technologies and Treatment for Diabetes. Wiley-Blackwell, Chichester UK, 2013, pages 189-205. 118) Skyler JS. Immune Intervention for Type 1 Diabetes 2012-2013. In: Phillip M, Battelino T (Editors). ATTD 2013 Year Book Advanced Technologies and Treatment for Diabetes. Wiley-Blackwell, Chichester UK, 2014, pages 181-195. 119) Skyler JS. Preservation and Prevention Strategies for Type 1 Diabetes. In: Umpierrez GE (Editor): Therapy for Diabetes Mellitus & Related Disorders, Sixth Edition. American Diabetes Association, Alexandria, Virginia, 2014, pages 116-127. 120) Skyler JS. Prevention of type 1 diabetes. In: DeFronzo RA, Ferrannini E, Zimmet P, Alberti KGMM (Editors): International Textbook of Diabetes Mellitus, Fourth Edition. John Wiley and Sons, Sussex, England, 2015, pages 541-549. 121) Skyler JS. Immune Intervention for Type 1 Diabetes, 2013-2014. In: Phillip M, Battelino T (Editors). ATTD 2014 Year Book Advanced Technologies and Treatment for Diabetes. Mary Ann Liebert Inc, New Rochelle, NY, 2015, pages 170-186. 122) Skyler JS, Krischer JP, Becker D, Rewers M. Prevention of Type 1 Diabetes. In: Diabetes in America, Third Edition. In Press. c. SYMPOSIA EDITED 1) Skyler JS (Editor): Symposium on Social Issues and Medicine. Archives of Internal Medicine 1971; 127:49-110 2) Skyler JS (Editor): The Walter Kempner Symposium. Archives of Internal Medicine 1974; 133:751-807 3) Skyler JS, Cahill GF (Editors): Symposium on Diabetes Mellitus. American Journal of Medicine 1981; 70: 101-214, 325-378, 579-626. 4) Skyler JS, Raptis S (Editors): Symposium on Biosynthetic Human Insulin. Diabetes Care 1981; 4:139-264 5) Skyler JS (Editor): Symposium on Human Insulin of Recombinant DNA Origin. Diabetes Care 1982; 5(Suppl. 2):1-186 6) Skyler JS (Editor): Symposium on Immunology and Diabetes. Diabetes/Metabolism Reviews 1987; 3: 723-1090. 7) Skyler JS (Editor): Symposium on Diabetes in Childhood and Adolescence. Pediatric Annals 1987; 16: 679-740. 8) Skyler JS (Guest Editor): Diabetic Control: Reducing the Risk of Complications? Diabetes Spectrum 1988; 1: 89-120. 9) Skyler JS, Erkelens W, Becker D (Editors): Human Insulin: A Decade of Experience and Future Developments. Diabetes Care 1993; 16 (Supplement 3): 1-165. 10) Skyler JS (Editor): Prevention & Treatment Of Diabetes & Its Complications. Medical Clinics of North America 1998; 82: 4: 665-979 (July 1998). 11) Skyler JS (Editor): Advances in Continuous Glucose Monitoring in Diabetes Mellitus. Diabetes Technology and Therapeutics 2000; 2:(Supplement 1): S1-S97. 12) Skyler JS. Islet Replacement Therapy. International Diabetes Monitor 2004; 16:(6):1-29 13) Skyler JS (Editor): Inhaled Insulin. Diabetes Technology and Therapeutics 2007; 9:(Supplement 1): S1-S114. 14) Skyler JS. Type 1 Diabetes. International Diabetes Monitor 2010; 22: 99-137. 3. REVIEW ARTICLES Jay S. Skyler Page 52 Curriculum Vitae 1) Dranov J, Skyler JS, Gunnells JC: Malignant Hypertension - Current Modes of Therapy. Archives of Internal Medicine 1974; 133:791-801 2) Mintz DH, Skyler JS, Chez RA: Diabetes Mellitus and Pregnancy. Diabetes Care 1978; 1:49-63 3) Blankenship GW, Skyler JS: Diabetic Retinopathy - A General Survey. Diabetes Care 1978; 1:127-137 4) Skyler JS: Clinical Implications: Exercise in Diabetes. Diabetes Care 1979; 2:307-311 5) Skyler JS: Complications of Diabetes Mellitus: Relationship to Metabolic Dysfunction. Diabetes Care 1979; 2:499-509 6) Skyler JS, Miller NE: The Use of Sweeteners by Diabetic Patients. Practical Cardiology 1980; 6(10):119-129 7) Skyler JS, Pfeiffer EF, Raptis S, Viberti GC: Biosynthetic Human Insulin: Progress and Prospects - An Overview. Diabetes Care 1981; 4:140-143 8) Citrin WS, Zigo MA, LaGreca A, Skyler JS: Group Strategies for Diabetes in Adolescence. Pediatric and Adolescent Endocrinology 1982; 10:219-223 9) Skyler JS: Psychosocial Aspects of Diabetes in Children and Adolescents: A Perspective of the Symposium. Pediatric and Adolescent Endocrinology 1983; 11:205-209 10) Skyler JS, Seigler DE, Reeves ML: A Comparison of Insulin Regimens in Insulin-Dependent Diabetes Mellitus. Diabetes Care 1982; 5(Suppl 1):11-18 11) Miller NE, O'Sullivan MJ, Skyler JS: Diabetes in Pregnancy: Nutritional Management. Perinatology/Neonatology 1983; 7(1):37-44 12) Skyler JS: Patient Self-Monitoring of Blood Glucose. Medical Clinics of North America 1982; 66:1227-1250 13) Skyler JS: Human Insulin of Recombinant DNA Origin: Clinical Potential. Diabetes Care 1982; 5(Suppl 2): 181-186 14) Skyler JS: Diabetes Update on Dx, Drugs and Diet. Modern Medicine 1982; 50(11);74-105 15) Skyler JS: Patient Self-Monitoring of Blood Glucose. Clinical Diabetes 1983; 1(4):12-17 16) Skyler JS: Dietary Planning in Insulin Dependent Diabetes Mellitus. Pediatric Annals 1983; 12:652-657 17) Skyler JS: Non-Insulin Dependent Diabetes Mellitus - A Clinical Strategy. Diabetes Care 1984; 7(Suppl 1):118-129 18) Skyler JS, Beatty CM, Goldberg RB: Managing Diabetes: An Updated Look at Diet. Geriatrics 1984; 39:7:57-68 19) Linn MW, Linn BS, Skyler JS, Edelstein J, Sandifer R: A Possible Role for Self-Management Techniques in Control of Diabetes. Diabetes Educator 1985; 11(2):13-16 20) Skyler JS: What's New in Today's & Tomorrow's Diabetes Therapy? Pharmacy Times 1985; 51:10:37-49 21) Rosenbloom AL, Malone JI, Morrison AD, Skyler JS: Screening for Diabetes Mellitus. Journal of the Florida Medical Association 1985; 72:1033-1037 22) Skyler JS, Bonheim R: Diabetes Self-Liberation. Rx Being Well 1986; 4(6):12-16, 42-44 23) Skyler JS: Insulin-Dependent Diabetes Mellitus: Flexibility in Contemporary Management. Postgraduate Medicine 1987; 81(6):163-174 24) Skyler JS: Immune Intervention Studies in Insulin-Dependent Diabetes Mellitus. Diabetes/Metabolism Reviews 1987; 3:10171035 25) Skyler JS, Rabinovitch A: Etiology and Pathogenesis of Insulin-Dependent Diabetes Mellitus. Pediatric Annals 1987; 16:682692 26) Skyler JS: Why Control Blood Glucose? Pediatric Annals 1987; 16:713-724 27) Skyler JS: How to Improve Diabetes Control. Diabetes in the News 1988; 5:1:32-34 Jay S. Skyler Page 53 Curriculum Vitae 28) Skyler JS: Insulin Pharmacology. Medical Clinics of North America 1988; 72:1337-1354 29) Skyler JS: Intensive Insulin Therapy - A Personal and Historical Perspective. Diabetes Educator 1989; 15:33-39 30) Skyler JS: Controversies and Directions in Diabetes Care. Jefferson Alumni Bulletin 1989; 38:4:25-28 31) Rabinovitch A, Skyler JS: Immunotherapy of Type I Diabetes. Medicographia 1990; 12:24-26,29 32) Donahue RP, Skyler JS, Schneiderman N, Prineas RJ: Hyperinsulinemia and Elevated Blood Pressure: Cause, Confounder, or Coincidence? American Journal of Epidemiology 1990; 132:827-836 33) Hirsch IB, Farkas-Hirsch R, Skyler JS: Intensive Insulin Therapy for the Treatment of Type I Diabetes Mellitus. Diabetes Care 1990; 13:1265-1283 34) Marks JB, Skyler JS: Clinical Review: Immunotherapy of Type I Diabetes Mellitus. Journal of Clinical Endocrinology & Metabolism 1991; 72:3-9 35) Marks JB, Skyler JS: Insulin Update. Pharmacy Times 1990; 56(10):102-110 36) Skyler JS: Strategies in Diabetes Mellitus: Start of a New Era. Postgraduate Medicine 1991; 89(6):45-63 37) Skyler JS: Is Tight Blood Sugar Control Effective and Justified? Affirmative. Hospital Practice 1992; 27:(Suppl 1):17-20,24-25 38) Skyler JS: Can Type I Diabetes Be Prevented? International Diabetes Monitor 1992; 4(6):1-6. 39) Skyler JS, Marks JB: Immune Intervention in Type I Diabetes Mellitus. Diabetes Reviews 1993; 1:15-42. 40) Skyler JS: Awaiting the DCCT. International Diabetes Monitor 1993; 5(2):1-3. 41) Skyler JS: The Impact of the DCCT. International Diabetes Monitor 1993; 5(3):1-3. 42) Burke GW, Alejandro R, Nery J, Roth D, Skyler JS, Ricordi C, Ciancio G, Miller J: Combined Kidney/Pancreas Transplantation in Diabetes Mellitus. Journal of the Florida Medical Association 1994: 81:339-343. 43) Skyler JS: Recent Advances in Insulin Therapy. The Diabetes Annual 1995; 10:193-207. 44) Skyler JS, Marks JB, Schneiderman N: Hypertension In Patients With Diabetes. American Journal of Hypertension 1995; 8:100S-105S. 45) Skyler JS: Diabetic Complications: Glucose Control Is Important. Endocrinology and Metabolism Clinics of North America 1996; 25:243-254. 46) Skyler JS: Insulin Therapy in Type II Diabetes: Who Needs It, How Much of It, and For How Long? Postgraduate Medicine 1997; 101(2):85-90,92-94,96. 47) Skyler JS: Tactics in Type 1 Diabetes. Endocrinology and Metabolism Clinics of North America 1997; 26: 647-657. 48) Rabinovitch A, Skyler JS: Prevention of Type 1 Diabetes. Medical Clinics of North America 1998; 82:739-755. 49) Skyler JS: Targeted Glycemic Control in Type 2 Diabetes. Journal of the Florida Medical Association 1998: 85:2:7-15. 50) Skyler JS: Prediction and Prevention of Type 1 Diabetes. Topical Endocrinology 1998: 10:6-9. 51) Skyler JS: Treating Diabetes: Rationale for Control. Managed Care Interface 1999; 12: Supplement 3: 10-14. 52) Skyler JS: New Diabetes Criteria and Clinical Implications. Drugs 1999; 58: Supplement 1: 1-2. 53) Beck-Nielsen H, Skyler J, Hanefeld M, Eschwege E, Finn J-R, DeFronzo R, Del Prato S, Bjorntorp P, Groop L, Haring H, Vague P, Charles A. Discussion . Drugs 1999; 58: Supplement 1: 75-82. 54) Skyler JS: The Economic Burden of Diabetes and the Benefits of Improved Glycemic Control: The Potential Role of a Continuous Glucose Monitoring System. Diabetes Technology and Therapeutics 2000; 2:(Supplement 1): S7-S12. Jay S. Skyler Page 54 Curriculum Vitae 55) Skyler JS: Microvascular Complications: Retinopathy and Nephropathy. Endocrinology and Metabolism Clinics of North America 2001; 30: 833-856. 56) Skyler JS, Oddo C. Diabetes Trends in the United States of America. Diabetes Metabolism Research Reviews 2002; 18(Supplement 3):S21-S26. 57) Home P, Chacra A, Chan J, Emslie-Smith A, Sorensen L, Van Crombrugge P, Boulton A, Davidson J, Dornan T, Heine R, Jimenez J, Kangas T, Kawamori R, Landgraf R, Massi-Benedetti M, Mogensen CE, Christiansen JS, Skyler J, Sorensen L, Uccioli L, Van Crombrugge P, Worldwide Initiative for Diabetes Education (WorldWIDE). Considerations on blood glucose management in type 2 diabetes mellitus. Diabetes Metabolism Research Reviews 2002; 18:273-285 58) Skyler JS. Evidence for Glycated Hemoglobin Targets from The Diabetes Control and Complications Trial. Endocrine Practice 2002; 8(Supplement 1):27-30. 59) Skyler JS. Diabetes Mellitus: Pathogenesis and Treatment Strategies. Journal of Medicinal Chemistry 2004; 47:4113-4117. 60) Skyler JS. DCCT: the study that forever changed the nature of treatment of type 1 diabetes. The British Journal of Diabetes and Vascular Disease 2004; 4:29-32. 61) Skyler JS. Effects of Glycemic Control on Diabetic Complications and on Prevention of Diabetes. Clinical Diabetes 2004; 22:162-166. 62) Skyler JS. Pulmonary Insulin Update. Diabetes Technology and Therapeutics 2005; 7:834-839. 63) Skyler JS. Pulmonary Insulin – Current Status. Diabetes Voice 2006; 51:1:23-25. 64) Skyler JS, Rafkin-Mervis LE. Inhaled Insulin – A New Tool in Diabetes Management. On the Cutting Edge 2006; 27:2:911,14. 65) Skyler JS. Prediction and Prevention of Type 1 Diabetes: Progress, Problems, and Prospects. Clinical Pharmacology and Therapeutics 2007; 81:768-771. 66) Skyler JS, Ponder S, Kruger D, Matheson D, Parkin CG. Is There a Place for Insulin Pump Therapy in Your Practice? Clinical Diabetes 2007; 25:50-56. 67) Ponder SW, Skyler JS, Kruger DF, Matheson D, Brown BW. Unexplained hyperglycemia in continuous subcutaneous insulin infusion: evaluation and treatment. Diabetes Educator 2008; 34:327-333 68) Skyler JS. Latent autoimmune diabetes in adults: the search for interventions continues. Nature Clinical Practice Endocrinology & Metabolism 2008; 4: 600-601. 69) Skyler JS. Glycemic control and cardiovascular disease. International Diabetes Monitor 2008; 20:183-187. 70) Lane W, Cochran E, Jackson JA, Scism-Bacon J, Corey I, Hirsch IB, Skyler JS. High-Dose Insulin Therapy: Is It Time for U-500 Insulin? Endocrine Practice 2009; 15:71-79. 71) Skyler, JS. Continuous Glucose Monitoring: An Overview of Its Development. Diabetes Technology and Therapeutics 2009; 11: (Supplement 1): S5-S10. 72) Cernea S, Raz I, Herold KC, Hirshberg B, Roep BO, Schatz DA, Fleming GA, Pozzilli P, Little R, Schloot NC, Leslie RDG, Skyler JS, Palmer JP. Challenges in Developing Endpoints for Type 1 Diabetes Intervention Studies. Diabetes Metabolism Research Reviews 2009; 25:694-704. 73) Aschner P, Horton E, Leiter LA, Munro N, Skyler JS on behalf of the Global Partnership for Effective Diabetes Management. Practical steps to improving the management of type 1 diabetes. Recommendations from the Global Partnership for Effective Diabetes Management. International Journal of Clinical Practice 2010; 64:305-315. 74) Skyler JS. Immunomodulation for type 1 diabetes mellitus. International Journal of Clinical Practice 2010; 64 (Suppl 166): 59-63 75) Skyler JS. Approaches to Interdicting Type 1 Diabetes. International Diabetes Monitor 2010; 22: 132-137. 76) Skyler, JS. Continuous Subcutaneous Insulin Infusion – A Historical Perspective. Diabetes Technology and Therapeutics 2010; 12: (Supplement 1): S5-S9. Jay S. Skyler Page 55 Curriculum Vitae 77) Skyler JS, Ricordi C. Stopping Type 1 Diabetes: Attempts to Prevent or Cure Type 1 Diabetes in Man. Diabetes 2011; 60:1-8. 78) 70. Skyler JS. Immune intervention for type 1 diabetes mellitus. International Journal of Clinical Practice 2011; (Suppl 170): 61- 79) 61. Skyler JS. Type 1 diabetes mellitus: immune intervention. International Journal of Clinical Practice 2012; (Suppl 175): 56- 80) Garg S, Skyler JS. New medications for the treatment of diabetes. International Journal of Clinical Practice 2012; (Suppl 175): 85-93. 81) Shuster JJ, Guo JD, Skyler JS. Meta-analysis of safety for low event-rate binomial trials. Research Synthesis Methods 2012; 3:30-50. 82) Skyler JS. The year in immune intervention for type 1 diabetes. Diabetes Technology and Therapeutics 2013; 15: Supplement 1:S88-S95. 83) Skyler JS. Primary and Secondary Prevention of Type 1 Diabetes. Diabetic Medicine 2013; 30:161-169. 84) Rustad JK, Musselman DL, Skyler JS, Matheson D, Delamater A, Kenyon NS, Caceda R, Nemeroff CB. Decision Making in Diabetes Mellitus Type 1. Journal of Neuropsychiatry and Clinical Neurosciences 2013;24:40-50. 85) Pugliese A, Skyler JS. Profiles in Progress – George S. Eisenbarth: Insulin and Type 1 Diabetes. Diabetes Care 2013; 36: 1437-1442. 86) Skyler JS, Pugliese A. Immunotherapy Trials for Type 1 Diabetes – the Contribution of George Eisenbarth. Diabetes Technology and Therapeutics 2013; 15: Supplement 2: S213-S220. 87) Hirsch IB, Buse JB, Leahy J, McGill JB, Peters A, Rodbard HW, Rubin RR, Skyler JS, Verderese CA, Riddle MC. Options for Prandial Glucose Management in Type 2 Diabetes Patients Using Basal Insulin: Addition of a Short-acting GLP-1 Analogue versus Progression to Basal-Bolus Therapy. Diabetes Obesity Metabolism 2014; 16:206-214. 88) Bailey CJ, Aschner P, Del Prato S, LaSalle J, Ji L, Matthaei S, and on behalf of the Global Partnership for Effective Diabetes Management [Skyler JS – Partnership Group Member]. Individualized glycaemic targets and pharmacotherapy in type 2 diabetes. Diabetes and Vascular Disease Research 2013; 10:397-409. 89) Harja E, Lord J, Skyler JS. Critique: An analysis of characteristics of subjects examined for incretin effects on pancreatic pathology. Diabetes Technology and Therapeutics 2013; 15: 609-618. 90) Skyler JS. Immune intervention for type 1 diabetes, 2012-2013. Diabetes Technology and Therapeutics 2014; 16 Supplement 1:S85-S91. 91) Peyser T, Dassau E, Breton M, Skyler JS. The artificial pancreas: current status and future prospects in the management of diabetes. Annals of the New York Academy of Sciences 2014; 1311:102-123. 92) Skyler JS. T1DM in 2014: Progress Towards a Bionic Pancreas. Nature Reviews Endocrinology 2015; 11:75-76 93) Skyler JS. Immune intervention for type 1 diabetes, 2013-2014. Diabetes Technology and Therapeutics 2015; 17 Supplment 1:S80-S87. 94) Skyler JS. The Prevention & Reversal of Type 1 Diabetes – Past Challenges & Future Opportunities. Diabetes Care 2015; 38:997-1007. 4. EDITORIALS, COMMENTARIES, and CRITIQUES 1) Skyler JS (Editor): Symposium on Social Issues and Medicine. Archives of Internal Medicine 1971; 127:49-11 (a) Introductory Remarks. Archives of Internal Medicine 1971; 127:50 (b) Concluding Remarks. Archives of Internal Medicine 1971; 127:110 2) Skyler JS: Differential Certification of Physician's Assistants. Archives of Internal Medicine 1973; 132:29 Jay S. Skyler Page 56 Curriculum Vitae 3) Skyler JS: Walter Kempner - A Biographical Note. Archives of Internal Medicine 1974; 133:752-755 4) Skyler JS: Diabetes Care - Striking a Balance. Diabetes Care 1978; 1:70 5) Skyler JS: Lipids, Diet, Diabetes, and Atherogenesis. Diabetes Care 1978; 1:138-139 6) Skyler JS: “Control” and Complications. Diabetes Care 1978; 1:204-205 7) Skyler JS: Sulfonylurea Drugs - 1978. Diabetes Care 1978; 1:205-206 8) Skyler JS: The UGDP and Insulin Therapy. Diabetes Care 1978; 1:328-329 9) Skyler JS: Thoughts Along the Way. Diabetes Care 1979; 2:58-59 10) Skyler JS: The Spectrum of Insulin Resistance. Diabetes Care 1979; 2:319-322 11) Skyler JS: Counter-Regulatory Hormones, Rebound Hyperglycemia, and Diabetic Control. Diabetes Care 1979; 2:526-529 12) Skyler JS: The Editor's Notebook. Diabetes Care 1980; 3:198-199 13) Skyler JS: Diabetes Mellitus: At Least Two Distinct Entities. Diabetes Care 1980; 3:395-396 14) Citrin W, Ellis GJ, Skyler JS: Glycosylated Hemoglobin: A Tool in Identifying Psychological Problems? Diabetes Care 1980; 3:563-564 15) Skyler JS: A Plethora of Insulins. Diabetes Care 1980; 3:638-639 16) Skyler JS, Cahill GF: Forward. Diabetes Mellitus: Progress and Directions. American Journal of Medicine 1981; 70:101-104 17) Skyler JS: The Editor Reflects... Diabetes Care 1981; 4:134-135 18) Skyler JS, Neelon FA: An Algebra For Adiposity. Diabetes Care 1981; 4:328-329 19) Skyler JS: The Shoulder Bag. Diabetes Care 1981; 4:331 20) Skyler JS: Evidence, Implications, and Corollaries. Diabetes Care 1981; 4:573-575 21) Skyler JS: Psychological Issues in Diabetes. Diabetes Care 1981; 4:656-657 22) Skyler JS: From The Editor's Desk... Diabetes Care 1982; 5:75-76 23) Skyler JS: Diabetic Retinopathy. JAMA 1982; 247:3246-3247 24) Skyler JS: Type II Diabetes: Towards Improved Understanding and Rational Therapy. Diabetes Care 1982; 5:447-448 25) Skyler JS: Type I Diabetes: Regimens, Targets & Caveats. Diabetes Care 1982; 5:547-552 26) Skyler JS: A Parting Word... Diabetes Care 1982; 5:642-643 27) Skyler JS: Control of Diabetes During Pregnancy - 1985. JAMA 1986; 247:647-648 28) Skyler JS: Lessons From Insulin Pharmacokinetics. Diabetes Care 1986; 9:666-668 29) Skyler JS: Introduction: Symposium on Immunology and Diabetes. Diabetes/Metabolism Reviews 1987; 3:723-724, 857-858 30) Skyler JS: Diabetic Control: Reducing the Risk of Complications? Introduction and Conclusions. Diabetes Spectrum 1988; 1:90, 118-120 31) Skyler JS: Keeping Up. International Diabetes Monitor 1989; 1:(1):1 32) Skyler JS: Overview: Progress in Diabetes Care. On The Cutting Edge Newsletter 1992; 13(4):2-3. 33) Skyler JS: Presidential Address. The Winds of Change. Diabetes 1993; 42:637-642. Jay S. Skyler 34) Page 57 Curriculum Vitae Skyler JS: Presidential Address. The Challenges of the Future. American Journal of Medical Sciences 1993; 305:5-9; and The Endocrinologist 1993; 3:233-238. 35) Skyler JS: Human Insulin After Ten Years. Diabetes Care 1993; 16(Suppl 3): 1-3. 36) Skyler JS: The Monitor After Five Years. International Diabetes Monitor 1994; 6:(1):1-2. 37) Skyler JS: Who Is The “Diabetes Team?” International Diabetes Monitor 1994; 6:(3):1-2. 38) Skyler JS: After the DCCT......... International Diabetes Monitor 1994; 6:(4):1-2. 39) Deeb LC, Skyler JS: Upgrading Diabetes Therapy. Now That We Know It Matters. Journal of the Florida Medical Association 1994: 81:599-602. 40) Skyler JS, Lefebvre P: Merging of Interests…..Broadening of Scope. International Diabetes Monitor 1995; 7:(1):1. 41) Skyler JS: Glucose Control is Important in Type 2, Too! International Diabetes Monitor 1996; 8:(6):1-2. 42) Skyler JS: Glucose Control in Type 2 Diabetes Mellitus. Annals of Internal Medicine 1997; 127:837-839. 43) Skyler JS, Lefebvre PJ: Beginning Year 10. International Diabetes Monitor 1998; 10:(1):1. 44) Skyler JS: Diabetes Mellitus - Facts & Paradoxes. Medical Clinics of North America 1998; 82:4:xi-xii. 45) Skyler JS: Simplifying the Diagnosis of Diabetes Mellitus. American Family Physician 1998; 58:1290-1292. 46) Skyler JS: UKPDS – What Does It Mean to Diabetes Management? International Diabetes Monitor 1999; 11:(2): 1-5. 47) Schatz DA, Krischer JP, Skyler JS: Now Is the Time to Prevent Type 1 Diabetes. Journal of Clinical Endocrinology and Metabolism 2000; 85: 495-498. 48) Skyler JS: Type 2 Diabetes: Insulin Secretion versus Insulin Action. International Diabetes Monitor 2000; 12:(3):1-3 49) Skyler JS, Lefebvre PJ: IDM – Changing with The Times. International Diabetes Monitor 2004; 16:(1):1 50) Skyler JS. Islet Replacement Therapy. International Diabetes Monitor 2004; 16:(6):1-2. 51) Skyler JS. PROactive Results Overstated and Misleading. DOCNews 2005; 2:(12):4. 52) Skyler JS. PROactive – A Sad Tale of Inappropriate Analysis and Unjustified Interpretation. Clinical Diabetes 2006; 24: 63-65. 52) Skyler JS. Cellular Therapy for Type 1 Diabetes Mellitus – Has The Time Come? JAMA 2007; 297:1599-1600. 53) Skyler JS. Pulmonary Insulin Delivery—State of the Art 2007. Diabetes Technology & Therapeutics 2007; 9: (Supplement 1): S1-S3. 54) Skyler JS, Lefebvre P, Feldt-Rasmussen B. The ‘Monitor’ evolves. Gutenberg requiescat in pace! International Diabetes Monitor 2007; 19:(6):1. 55) Skyler JS. Thirty Years of Diabetes Care – Reflections on the Beginning. Diabetes Care 2008; 31: 183-184. 56) Skyler JS. CGM – A Technology in Evolution. Diabetes Technology and Therapeutics 2009; 11: 63-64. 57) Garg, SK, Hirsch IB, Skyler JS. Insulin Glargine and Cancer—An Unsubstantiated Allegation. Diabetes Technology and Therapeutics 2009; 11: 473-476. 58) Skyler JS. Probing Type 1 Diabetes. International Diabetes Monitor 2010; 22: 99-100. 59) Skyler JS. Glycemia and Cardiovascular Diseases in Type 2 Diabetes. Journal of Internal Medicine 2010; 268: 468-470. 60) Skyler JS, Sosenko JM. The Evolution of Type 1 Diabetes. JAMA 2013; 309:2491-2492. 61) Skyler JS. The Compelling Case for Anti-CD3 in Type 1 Diabetes. Diabetes 2013; 62:3656-3657. Jay S. Skyler Page 58 Curriculum Vitae 62) Skyler JS. Antithymocyte Globulin in Type 1 Diabetes – An Unanswered Question. Lancet Diabetes & Endocrinology 2013; 1: 265-266. 63) Skyler JS. Struggles with Clinical Translation of Immune Intervention Trials. Diabetes Care 2014; 37: 1173-1175. 64) Skyler JS. Characterizing Subgroups of Type 1 Diabetes. Diabetes 2014; 63:3578-3580. 65) Skyler JS. Immune Therapy for Treating Type 1 Diabetes: Challenging Existing Paradigms. Journal of Clinical Investigation 2015; 125:94-96. 66) Skyler JS. Towards Primary Prevention of Type 1 Diabetes. JAMA 2015; 313:1520-1521. 67) Cefalu WT, Tamborlane WV, Skyler JS. Type 1 Diabetes at a Crossroad! Diabetes Care 2015; 38: 968-970. . 5. POSITION STATEMENTS 1) Assan R, Bach JF, Czernichow P, Dupre J, Stiller CR, Eisenbarth GS, Gries FA, Kolb H, Harrison LC, Lafferty K, Maclaren NK, Nerup J, Rabinovitch A, Skyler J: Immunosuppressive Drugs in Diabetes. Lancet 1986; 2:1097 2) Kolb H, Bach JF, Eisenbarth GS, Harrison LC, Maclaren NK, Pozzilli P, Skyler J, Stiller CR: Criteria for Immune Trials in Type I Diabetes. Lancet 1989; 2:686 3) American Diabetes Association Ad Hoc Expert Committee [Jay S. Skyler, Chairman]. Prevention of Type I Diabetes Mellitus. Diabetes 1990; 39:1151-1152 and Diabetes Care 1990; 13:1026-1027. 4) Robbins DC, Andersen L, Bowsher R, Chance R, Dinesen B, Frank B, Gingerich R, Goldstein D, Widemeyer H-M, Haffner S, Hales CN, Jarett L, Polonsky K, Porte D, Skyler J, Webb G, Gallagher K: Report of the American Diabetes Association Task Force on Standardization of the Insulin Assay. Diabetes 1996; 45:242-256. 5) American College of Physicians [Ginsburg JA, Addington WW, Bertram PD, Eisenberg JM, Fogarty WM, Gary NE, Gullen DJ, Herbert-Carter J, Honsinger R Jr, Kamholz SL, Latos DL, Lavizzo-Mourey RJ, Riley WJ, Tompkins RK, Webster J, Thomson GE, Cassel CK, Reynolds WA, Murray J, Khan FA, Sidorov J, Skyler JS, Smith LG, Vanselow N, Whitcomb M]. The Physician Workforce and Financing of Graduate Medical Education. Annals of Internal Medicine 1998;128:142-148. 6) Palmer JP, Fleming GA, Greenbaum CJ, Herold KC, Jansa LD, Kolb H, Lachin JM, Polonsky KS, Pozzilli P, Skyler JS, Steffes MW. C-peptide is the Appropriate Outcome Measure for Type 1 Diabetes Clinical Trials to Preserve Beta Cell Function: Report of an ADA Workshop, 21-22 October 2001. Diabetes 2004; 53:250-264. 7) Skyler JS, Bergenstal R, Bonow RO, Buse J, Deedwania P, Gale EAM, Howard BV, Kirkman MS, Kosiborod M, Reaven P, Sherwin RS. Intensive Glycemic Control and the Prevention of Cardiovascular Events: Implications of the ACCORD, ADVANCE, and VADT Diabetes Trials. A Position Statement of the American Diabetes Association and A Scientific Statement of the American College of Cardiology Foundation and the American Heart Association. Diabetes Care 2009; 32: 187-192, Circulation 2009; 119:351-357, and Journal of the American College of Cardiology 2009: 53:298-304. 8) Insel RA, Dunne JL, Atkinson MA, Chiang JL, Dabelea D, Gottlieb PA, Greenbaum CJ, Herold KC, Krischer JP, Lernmark A, Ratner RE, Rewers MJ, Schatz DA, Skyler JS, Sosenko JM, Ziegler AG. Staging Presymptomatic Type 1 Diabetes: A Scientific Statement of JDRF, the Endocrine Society, and the American Diabetes Association. Diabetes Care 2015; 38:1964-1974. 6. LETTERS TO THE EDITOR 1) Skyler JS: Medical Student Dissent Deplored. New England Journal of Medicine 1968; 278:624-625 2) Skyler JS: Detecting Hypothyroidism. Lancet 1969; 1:259 3) Skyler JS, Skyler DL, Seigler DE, O'Sullivan MJ: Algorithms: Reply. Diabetes Care 1981; 4:506 4) Skyler JS: Management of Diabetic Retinopathy. JAMA 1982; 248:2970-2971 5) Skyler JS: Diabetic Control and Fetal Malformations. New England Journal of Medicine 1988; 319:648 Jay S. Skyler Page 59 Curriculum Vitae 6) Skyler JS. Competing Perspectives on PROactive – Response from Dr. Skyler. Clinical Diabetes 2007; 25:3-4 7) Skyler JS. Intensive Glycemic Control and the Prevention of Cardiovascular Events: Implications of the ACCORD, ADVANCE, and VA Diabetes Trials: A Position Statement of the American Diabetes Association and a Scientific Statement of the American College of Cardiology Foundation and the American Heart Association. Diabetes Care 2009; 32:e92-93. 7. OTHER PROFESSIONAL ITEMS a. AUDIOTAPES 1) Skyler JS: Management Strategy for Type II Diabetes. Audio-Digest 1988; 35:7 b. VIDEOTAPES 1) Skyler JS, Sherwin RS, Jovanovic L: Diabetes Mellitus: Advances in Control, Exercise, and Pregnancy. NCME Program #409, Network for Continuing Medical Eudcation, New York, 1983 2) Skyler JS, Feldman JM: Modern Management of Diabetes. Eli Lilly & Co. Pharmaceutical Division Video Communications, Indianapolis, 1983 3) Skyler JS: Pathogenesis of Type I Diabetes. In: Davidson MB, Video-Clinic - Diabetes Mellitus - Tape 1. American Medical Association AMA-CME Video Clinics, 1984 4) Skyler JS, Campbell K: Principles of Diabetic Management - Modern Management. Pharmacy Update. American Medical Video, 1990 5) Skyler JS, Campbell K: Principles of Diabetic Management - Monitoring the Diabetic Patient. Pharmacy Update. American Medical Video, 1990 6) Skyler JS, Weir G: Prediction and Prevention of Diabetic Renal Disease. In: Bone R, Internal Medicine Update #9105. American College of Physicians & Lifetime Television Network, 1991 7) Skyler JS, Weir G: Emerging Treatments for Diabetes. In: Bone R, Internal Medicine Update #9106. American College of Physicians & Lifetime Television Network, 1991 8. PUBLICATIONS ABOUT JAY S. SKYLER 1) About the Editors and Editorial Board. Diabetes Care 1978; 1(1):XX 2) Service FJ: Jay Skyler and Diabetes Care. Diabetes Care 1983; 6:100 3) Biographical Note: Jay S. Skyler, M.D. Diabetes Spectrum 1988; 1:120. Jay S. Skyler 9. PUBLISHED ABSTRACTS Page 60 Curriculum Vitae 1) Bivins CH, Lebovitz HE, Skyler JS, Feldman JM: Enhancement of Insulin Secretion in Acromegaly by Serotonin Antagonists. Diabetes 1972; 21:352 2) Skyler JS, Newborg BC, Peschel RL, Kempner W: Weight Reduction of the Massively Obese. Clinical Research 1974; 22:569A 3) Skyler JS, Rogol AD, Knazek RA, Lovenberg W: Characterization of Growth Hormone and Prolactin Produced by Human Tumor Culture. Clinical Research 1974; 22:713A 4) Skyler JS, Knazek RA, Rogol AD, Lovenberg W: Characterization of Growth Hormone and Prolactin Produced by Human Tumor Culture. Clinical Research 1975; 23:423A 5) Knazek R, Skyler JS: Production of Human Prolactin by Pituitary Adenomata Grown on Artificial Capillaries. Program of the 57th Annual Meeting of the Endocrine Society 1975; #426, p 264 6) Baumann G, Skyler JS, Chrambach A: Preparation of Isohormones of Human Growth Hormone in Milligram Amounts by Isoelectric Focusing. Program of the 57th Annual Meeting of the Endocrine Society 1975; #122, p 111 7) Zweerink HJ, Morgan EM, White CK, Skyler JS: Structure and Function of Subviral Particles in Reovirus Infected Cells. Proceedings of the Third International Congress for Virology 1975 8) Skyler JS, Chrambach A: Catalogue of Isohormones of Human Growth Hormone. Program of the International Symposium on Growth Hormone and Related Peptides, Milan, Italy, 1975; p 14 9) Knazek RA, Skyler JS: Production of Growth Hormone and Prolactin in Tissue Culture. Program of the International Symposium on Growth Hormone and Related Peptides, Milan, Italy, 1975; p 131 10) Skyler JS, Robertson EG, Skyler DL, Lasky IA, Burkett G, McLeod AGW, O'Sullivan MJ: Blood Glucose Control During Pregnancy. Program of the Southern Sugar Club 1979 11) Citrin W, Ellis GJ, Skyler JS: A Therapeutic Paradigm for Discrepant Urine Records. Diabetes 1980: 29(Suppl 2):42A 12) Scott CS, Skyler JS: Cultural Beliefs Influence Compliance to Therapy for Diabetes Mellitus. Diabetes 1980; 29(Suppl 2):6A 13) Harris R, Linn MW, Pollack L, Tewksbury D, Skyler JS: Relationship Between the Health Belief Model and Compliance as a Basis for Intervention. Diabetes 1981; 30(Suppl 1):98A 14) Citrin WS, Zigo MA, Skyler JS: Multi-Family Group Meetings Alter Feelings, Behavior and Management of Diabetes in Adolescents. Diabetes 1981; 30(Suppl 1):140A 15) Seigler DE, Reeves ML, Ryan EA, Goldberg RB, Skyler JS: Glycemic Control with Intensified Conventional Therapy. Diabetologia 1981; 21:326-327 16) Skyler JS, Seigler DE, Reeves ML, Ryan EA, Goldberg RB: Glycemic Control Using Intensified Conventional Therapy and Patient SelfMonitoring of Blood Glucose. Bulletin of the International Study Group of Diabetes in Children and Adolescents 1981 17) Reeves ML, Seigler DE, Ryan EA, Goldberg RB, Skyler JS: Comparison of Intensified Conventional Therapy and Continuous Subcutaneous Insulin Infusion in Outpatient Management of Type I Diabetes Mellitus. Diabetologia 1981; 21:512-513 18) Skyler JS, Reeves ML, Seigler DE, Ryan EA: Self-Monitoring of Blood Glucose and Intensive Conventional Therapy: Comparison with Continuous Subcutaneous Insulin Infusion in Insulin-Dependent Diabetes Mellitus. Abstracts of the International Symposium on Artifician Systems for Insulin Delivery, Assisi, 1981; p 112 19) Citrin WS, Zigo MA, LaGreca A, Skyler JS: Diabetes in Adolescence: Effects of Multi-Family Group Therapy and Parent Simulation of Diabetes. Diabetes 1982; 31(Suppl 2):13A 20) Ryan EA, Brower E, O'Sullivan MJ, Skyler JS: Insulin Resistance in Pregnancy. Diabetes 1982; 31(Suppl 2):31A 21) Ryan EA, Brower E, O'Sullivan MJ, Skyler JS: Changes in Insulin Action Associated with Pregnancy. Proceedings of the British Diabetic Association. Diabetologia 1982; 23:474 22) Linn MW, Linn BS, Skyler JS, Jensen J: Stress and Immune Function in Diabetes. Psychosomatic Medicine 1982; 44:128 23) Kubrusly DB, Goldberg RB, Fournier AM, Skyler JS, Hsia SL, Sosenko JM: Association Between Plasma Lipoprotein, Components and Glycmeia in Normal Women. Clinical Research 1984; 33:225A 24) Sosenko JM, Pasin RA, Kubrusly DB, Weintraub J, Skyler JS, Boulton AJM: Heart Rate, Autonomic Function, and Glycemia in Young Type I Diabetes Patients. Diabetes 1984; 33(Suppl 1):91A 25) Boulton AJM, Kubrusly DB, Bowker JH, Skyler JS, Becker DM, Sosenko JM: The Importance of Diabetic Peripheral Neuropathy in the Etiology of Foot Ulceration. Proceedings of the Diabetic Peripheral Neuropathy Meeting 1984 Jay S. Skyler Page 61 Curriculum Vitae 26) Sosenko JM, Gadia MT, Fournier AM, O'Connell MT, Aguiar MC, Skyler JS: Body Stature: A Major Risk Factor for Diabetic Sensory Neuropathy. Clinical Research 1985; 33:445A 27) Seigler DE, Reeves ML, Goldberg RB, Lohman VL, Agramonte RF, Ashby MH, Skyler JS: Pharmacokinetics of Ultralente Insulin Preparations. Diabetes 1985; 34(Suppl 1):61A 28) Boulton AJM, Abouganem D, Penneys NL, Angus E, Skyler JS: A Clinicopathologic Study of Necrobiosis Lipoidica Diabeticorum. Diabetes 1985; 34(Suppl 1):102A 29) Boulton AJM, Kubrusly DB, Gadia M, Quintero LC, Bowker JH, Skyler JS, Sosenko JM: The Etiology and Prognosis of Diabetic Foot Ulceration. Diabetes Research & Clinical Practice 1985; 1(Suppl 1):S65 30) Schiffrin A, Belmonte M, Sheinvold FL, Rabinovitch A, Skyler J: A Prospective Study of the Natural Course of Beta-Cell Function in InsulinDependent Diabetic Children. Diabetes Research & Clinical Practice 1985; 1(Suppl 1):S499 31) Seigler DE, Reeves ML, Goldberg RB, Lohman VL, Agramonte, RF, Ashby MH, Skyler JS: Pharmacokinetics of Long-Acting (Ultralente) Insulin Preparations. Diabetes Research & Clinical Practice 1985; 1(Suppl 1):S508 32) Gadia MT, Ayyar DR, Ramos LB, Natori N, Skyler JS, Sosenko JM: The Association Between Diabetic Neurological Dysfunction and Body Stature. Diabetes 1986; 35(Suppl 1):103A 33) Sosenko JM, Gadia MT, Goldberg RB, Hsia SL, Fournier AM, Skyler JS: The Association Between HDL-2-Cholesterol and Insulin in Nondiabetic Women. Clinical Research 1986; 34:555A 34) Fournier AM, Gadia MT, Kubrusly DB, Skyler JS, Sosenko JM: Blood Pressure, Insulin and Glycemia in Non-Diabetic Individuals. Clinical Research 1986; 34:817A 35) Boulton AJM and The Tolrestat Neuropathy Study Group: Effects of Tolrestat, A New Aldose Reductase Inhibitor, on Nerve Conduction and Paresthetic Symptoms in Diabetic Neuropathy. Diabetologia 1986; 29:521A 36) Seigler DE, Olsson M, Skyler JS: Use of Human Ultralente Insulin in IDDM. Diabetes 1987; 36(Suppl 1):76A 37) Olsson M, Seigler DE, Lohman VL, Agramonte RF, Ashby MH, Skyler JS: Protamine Content Does Not Influence the Pharmacokinetics of Human NPH Insulin. Diabetes 1987; 36(Suppl 1):132A 38) Seigler DE, Olsson GM, Skyler JS: Morning versus Bedtime NPH Insulin in Type II (Non-Insulin Dependent) Diabetes Mellitus. Diabetologia 1987; 30:581A 39) Skyler JS for the Miami Cyclosporine Diabetes Study Group: Cyclosporine in Insulin Dependent Diabetes Mellitus: Effects on Islet Beta Cell Function. The Second International Congress on Cyclosporine Abstracts 1987; pg 88 40) Herbst JS, Hirsch IB, Skyler JS: The Effect of Ejaculation on Microalbuminuria. Diabetes 1988; 37(Suppl 1):130A 41) Skyler JS, Rabinovitch A, Fletcher MA, and the Miami Cyclosporine Diabetes Study Group: Increased Activated Macrophage/Monocytes and Natural Killer Cells At Diagnosis Of Insulin-Dependent Diabetes Mellitus (IDDM). International Congress on Immunointervention in Autoimmune Diseases Abstracts 1988; Workshop 14 42) Skyler JS, Rabinovitch A, and the Miami Cyclosporine Diabetes Study Group: Islet Beta Cell Function in Insulin-Dependent Diabetes Mellitus (IDDM) Treated with Cyclosporine (CY). International Congress on Immunointervention in Autoimmune Diseases Abstracts 1988; Workshop 23 43) Skyler JS: Intensive Insulin Therapy - 1988. Third International Symposium on Treatment of Diabetes Mellitus, Nagoya Japan, Program and Abstracts 1988; pg 36 44) Skyler JS for the Miami Cyclosporine Diabetes Study Group: Cyclosporine in Insulin Dependent Diabetes Mellitus: Effects on Islet Beta Cell Function. 8th International Congress of Endocrinology Abstracts 1988; pg 506 45) Ireland S, Freeman C, Greco P, Gutt M, Wick P, Skyler JS, LaGreca AM: Diabetes-Specific Coping for Adults with IDDM. Diabetes 1989; 38(Suppl 2):108A 46) Ireland S, LaGreca AM, Agramonte R, Greco P, Freeman C, Gutt M, Skyler JS: Autonomic Neuropathy Among Adults With IDDM: Relationships With Metabolic Control and Measures of Stress, Anger, and Hostility. Proceedings Society of Behavioral Medicine 1990 47) Peckerman A, Saab PG, McCabe PM, Skyler JS, Winters RW, Schneiderman N: Cold Pressor Pain and Cardiovascular Reactivity During the Forehead Cold Stimulation Procedure. Proceedings Society of Behavioral Medicine 1990 48) Greco P, LaGreca AM, Ireland S, Freeman C, Gutt M, Agramonte, R, Skyler JS: Components of Diabetes Knowledge as Predictors of Metabolic Control Among Adults With IDDM. Proceedings Society of Behavioral Medicine 1990 49) Freeman CR, Hurwitz BE, Agramonte RA, Quillian RE, Schneiderman N, Skyler JS: Cardiovascular Response in Type I Diabetics at Rest and in Response to Autonomic Stimulation. Diabetes 1990; 39(Suppl):184A Jay S. Skyler Page 62 Curriculum Vitae 50) Greco P, LaGreca AM, Ireland S, Wick P, Freeman C, Agramonte R, Skyler JS: Assessing Adherence in IDDM: A Comparison of Two Methods. Diabetes 1990; 39(Suppl):165A 51) Freeman CR, Hurwitz BE, LaGreca AM, Nagel JH, Schneiderman N, Skyler JS: Defects in Autonomic Mediation of Cardiovascular Functioning in Type I Diabetics. Psychophysiology 1990; 27:S33 52) Quillian RE, Marks JB, Hurwitz BE, Thompson NE, Ansley J, Schneiderman N, Skyler JS: Acute Effects of Induced Hyperinsulinemia on Blood Pressure & Sympathetic Tone in Healthy Men. Clinical Research 1990; 38:993A 53) Ansley J, Marks JB, Hurwitz BE, Thompson NE, Quillian RE, Olsson-Istel GM, Ashby M, Spitzer S, Fili M, Donahue RDP, Schneiderman N, Skyler JS: Insulin Resistance and Blood Pressure. Proceedings of Society of Behavioral Medicine 1991; pg 88 54) LaGreca AM, Auslander W, Spetter D, Greco P, Skyler JS, Fisher EB, Santiago JV: Adolescents with IDDM: Family and Peer Support of Diabetes Care. Proceedings of Society of Behavioral Medicine 1991; pg 110 55) Wick P, LaGreca A, Greco P, Ireland S, Agramonte R, Skyler J: Stress, Social Support, and Adherence: Relationships with Metabolic Control in Adults with IDDM. Proceedings of Society of Behavioral Medicine 1991; pg 187 72) Marks JB, Hurwitz BE, Ansley J, Quillian RE, Thompson NE, Olsson-Istel GM, Spitzer S, Schneiderman N, Skyler JS: Effects of Induced Hyperinsulinemia on Blood Pressure & Sympathetic Tone in Healthy Volunteers. Diabetes 1991; 40(Suppl 1):367A 73) Hurwitz BE, Marks JB, Freeman CR, LaGreca AM, Nagel JH, Agramonte RF, Schneiderman N, Skyler JS: Sympathetic Dysfunction Occurs Early in the Course of Cardiovascular Autonomic Neuropathy. Diabetes 1991; 40(Suppl 1):330A 74) Thompson NE, Marks JB, Hurwitz BE, Quillian RE, Ansley J, Spitzer S, Schneiderman N, Skyler JS: Insulin Resistance Dampens the Acute Effects of Insulin on Blood Pressure Regulation. Diabetes 1991; 40(Suppl 1):366A 75) LaGreca AM, Hurwitz BE, Freeman CR, Wick P, Ireland S, Agramonte RF, Marks JB, Schneiderman N, Skyler JS: Autonomic Dysfunction in Adults with IDDM: Implications for Psychosocial Functioning. Diabetes 1991; 40(Suppl 1):431A 76) Wick P, LaGreca AM, Greco P, Ireland S, Agramonte RF, Skyler JS: Stress, Social Support, Adherence, and Metabolic Control in Adults with IDDM. Diabetes 1991; 40(Suppl 1):538A 77) Greco P, LaGreca AM, Auslander W, Spetter D, Skyler JS, Fisher EB, Santiago JV: Family and Peer Support of Diabetes Care Among Adolescents. Diabetes 1991; 40(Suppl 1):537A 78) Fisher E, Greco P, Spetter D, Quillian R, Skyler J, LaGreca A: Specific and General Characteristics of Social Support in Diabetes Care: Relationship with Adherence and Metabolic Control. Diabetes 1991; 40(Suppl 1):538A 79) Schwartz S, Skyler J, Palmer J, Einhorn D, Eisenbarth G, Ma J, Byers V: Treatment of New Onset Type I Diabetes with a Pan T Lymphocyte Immunoconjugate, H65-RTA. Diabetes 1991; 40(Suppl 1):58A 80) Skyler JS, Byers V, Einhorn D, Eisenbarth G, Lorenz T, Palmer J, Saria E. Schwartz S: Effects of An Anti-CD5 Immunoconjugate (H65-RTA) on Pancreatic Islet Beta Cell Function in Type I Diabetes Mellitus. Diabetes Research & Clinical Practice 1991; 14(Suppl 1):S54 81) Pass M, Gellman MD, Landel J, LaGreca A, Skyler JS, Schneiderman N: Duration of Type I Diabetes, Metabolic Control, and Depression and Hostility. Proceedings of Society of Behavioral Medicine 1992 82) Landel J, Gellman MD, Skyler JS, LaGreca A, Schneiderman N: Comparing Casual and Ambulatory Blood Pressure and Heart Rate in Subjects with Type I Diabetes. Proceedings of Society of Behavioral Medicine 1992 83) Landel J, LaGreca A, Schneiderman N, Skyler JS: Adults with IDDM: The Role of Family Functioning in Diabetes Care. Proceedings of Society of Behavioral Medicine 1994 84) Donahue RP, Donahue RD, Prineas RJ, Gutt M, Skyler JS, Schneiderman N: Blood Pressure and Insulin Sensitivity in a Biethnic Sample. The Miami Community Health Study. Circulation Research. 85) Marks JB, Thompson NE, Ironson GH, Durel LA, Yount SE, Gellman M, Garza R, Benight C, Skyler JS, Schneiderman N: Sodium Intake Affects Blood Pressure in Insulin Resistant Subjects. Diabetes 1994; 43(Suppl 1):100A 86) DPT-1 Study Group. The Diabetes Prevention Trial of Type I Diabetes (DPT-1). Diabetes 1994; 43(Suppl 1):159A 87) DPT-1 Study Group. The Diabetes Prevention Trial-Type 1 Diabetes (DPT-1): Implementation of Screening and Staging of Relatives. Diabetes 1995; 44(Suppl 1):129A. 88) Schatz D for the DPT-1 Study Group. The Diabetes Prevention Trial-Type 1 Diabetes (DPT-1): Design and Implementation of the Oral Antigen (Insulin) Protocol. Diabetes 1995; 44(Suppl 1):230A. 89) Skyler JS: Hypertension In Diabetes. American Journal of Hypertension 1995; 8:5A. 90) Skyler JS: Insulin Resistance And Hyperinsulinemia: Which Is The Culprit? Psychosomatic Medicine 1995; 57:64. Jay S. Skyler Page 63 Curriculum Vitae 91) DPT-1 Study Group. The Diabetes Prevention Trial-Type 1 Diabetes (DPT-1): Progress Report. Autoimmunity 1995; 21:66. 92) Landel J, Delameter AM, Schneiderman N, Skyler JS: The Medical Team’s Role in Health Outcomes in Gestational Diabetes. Proceedings of Society of Behavioral Medicine 1996. 93). Landel J, Delameter AM, Schneiderman N, Skyler JS: Adherence Predicts Glycemia in Women with Gestational Diabetes. Proceedings of Society of Behavioral Medicine 1996. 94). Davis CL, Gutt M, Doherty K, Skyler JS, Marks J, Weber S, Thompson N, Schneiderman N: Postpartum Metabolic Markers of Gestational Diabetes. Annals of Behavioral Medicine 1996; (International Congress Supplement): S234. 95). Gellman MD, Ironson GH, Marks JB, Spencer S, Czarnecki E, Durel LA, Skyler JS, Schneiderman N: The Relationship Between Insulin Resistance and Sodium Sensitivity Using Multiple Blood Pressure Measurements. Proceedings of Society of Behavioral Medicine 1996. 96). Marks JB, Weber SL, Miceli GR, Gutt M, Doheny K, Skyler JS: Metformin Does Not Improve Insulin Sensitivity in Insulin Resistant Normoglycemic Women with Hirsutism. Proceedings of 10th International Congress of Endocrinology 1996; I:564. 97). Gutt M, Marks JB, Weber SL, Doheny K, Davis K, Gallagher CK, Schneiderman N, Skyler JS: Generalized Metabolic Syndrome Found in Postpartum Women with a History of Diabetes and/or Hypertension. Proceedings of 10th International Congress of Endocrinology 1996; II:881. 98). Motivala SJ, Hurwitz BE, LaGreca AM, Skyler JS, Schneiderman N. Diminished Parasympathetic Cardiac Input Predicts Differences in Psychosocial Functioning. Proceedings of 4th International Congress of Behavioral Medicine 1996; AD3. 99). Eisenbarth GS, Krischer J, Greenbaum C, Schatz D, Skyler J, for the DPT-1 Study Group. Differential Expression of Autoantibodies by DQA1*0102,DQB1*0602+ Relatives of The Diabetes Prevention Trial-1 (DPT-1). Autoimmunity 1996; 24(Suppl 1):52. 100). DPT-1 Study Group. The Diabetes Prevention Trial-Type 1 Diabetes (DPT-1): Enrollment Report. Diabetes 1997; 46(Suppl 1):163A. 101). DPT-1 Study Group. Demographics of Relatives Screened and ICA Positive in The Diabetes Prevention Trial-Type 1 Diabetes (DPT-1). Diabetes 1997; 46(Suppl 1):142A. 102). DPT-1 Study Group. The Diabetes Prevention Trial-Type 1 Diabetes (DPT-1): Progress Report. Diabetologia 1997; 40(Suppl 1):A66. 103). DPT-1 Study Group. The Diabetes Prevention Trial-Type 1 Diabetes (DPT-1): Demographics of Relatives Screened and ICA Positive. Diabetologia 1997; 40(Suppl 1):A78. 104). Eisenbarth GS, Krischer J, Greenbaum C, Schatz D, Skyler J, for the DPT-1 Study Group. Role of DQA1*0102/DQB1*0602 In Risk Characterization: The Diabetes Prevention Trial-Type 1 Diabetes (DPT-1). Diabetologia 1997; 40(Suppl 1):A48. 105). Eastman RC, Cowie CC, Harmon J, and the DPT-1 Study Group. Potential Cost-Effectiveness of Primary Prevention of Insulin-Dependent Diabetes Mellitus. Diabetologia 1997; 40(Suppl 1):A39. 106). Gutt M, Marks JB, Weber SL, Spitzer S, Schneiderman N, Skyler JS: Insulin Sensitivity Measurements: Comparison of Euglycemic Clamp and Insulin Sensitivity Index Derived from Oral Glucose Tolerance Test. Proceedings of 79th Annual Meeting of The Endocrine Society 1997; 476. 107). Davis, C., Gutt, M., Marks, J., Llabre, M., Schneiderman, N., & Skyler, J. Differences in glucose/insulin metabolism among postpartum gestational diabetics and normals. Annals of Behavioral Medicine 1997; 19 (Suppl.): S119. 108). Gutt, M., Marks, J., Weber, S., Spitzer, S., Davis, C., Gallaher, C., Schneiderman, N., & Skyler, J. Do gestational women with compromised cardiovascular risk profiles recover in the postpartum state? Annals of Behavioral Medicine 1997; 19 (Suppl.): S124. 109). Marks JB, Weber SL, Miceli GR, Van Splunteren F, Davis CL, Spitzer S, Schneiderman N, Skyler JS. Metformin Affects Sex Hormone Levels In Women With Hyperandrogenism Independent Of Effects On Insulin Or Insulin Sensitivity. Diabetes 1998; 47(Suppl 1):A196. 110). Skyler JS, Gelfand RA, Kourides IA, for the Inhaled Insulin Phase II Study Group. Treatment of Type 1 Diabetes Mellitus with Inhaled Insulin: A 3-Month Multicenter Study. Diabetes 1998; 47(Suppl 1):A61. 111). Cefalu WT, Gelfand RA, Kourides IA, for the Inhaled Insulin Phase II Study Group. Treatment of Type 2 Diabetes Mellitus with Inhaled Insulin: A 3-Month Multicenter Study. Diabetes 1998; 47(Suppl 1):A61. 112). Cowie C, Cuthbertson D, Krischer J, Wilson D, Maclaren N, and the DPT-1 Study Group. Demographic Characteristics of Islet Cell Antibody Positivity (ICA+) in The Diabetes Prevention Trial for Type 1 Diabetes (DPT-1). Diabetes 1998; 47(Suppl 1):A146. 113). Greenbaum CJ, Zeidler A, Schatz D, Eisenbarth G, Cuthbertson D, Krischer J, and the DPT-1 Study Group Characteristics of HLA DQA1*0102 DQB1*0602 Relatives Identified in The Diabetes Prevention Trial - Type 1 Diabetes (DPT-1). Diabetes 1998; 47(Suppl 1):A236. 114). Greenbaum CJ, Cuthbertson D, Krischer J, and the DPT-1 Study Group. Undiagnosed Hyperglycemia in Relatives of Type 1 Diabetes Patients. Diabetes 1998; 47(Suppl 1):A236. 115). Gutt M, Marks JB, Davis CL, Spitzer S, Llabre M, Schneiderman N, Skyler JS: Identifiaction of a Simple Technique to Estimate A Insulin Sensitivity Index. Proceedings of 80th Annual Meeting of The Endocrine Society 1998. Jay S. Skyler Page 64 Curriculum Vitae 116). Hernandez-Cassis C, Marks JB, Hernandez CK, Skyler JS. Insulin secretion Precedes Glucose Rise During a Frequent Sampling Oral Glucose Tolerance Test. Proceedings of 80th Annual Meeting of The Endocrine Society 1998. 117). Davis, C., Gutt, M., Llabre, M., Marks, J., Gallaher, C., Leo, T., Landel, J., Skyler, J., & Schneiderman, N. Gestational diabetes and CAD risk factors: It's all about "M". Annals of Behavioral Medicine 1998; 20 (Suppl.), S078. 118). Gallaher, C., Hurwitz, B., Gutt, M., Marks, J., Llabre, M., Skyler, J., Davis, C., Landel, J., Leo, T., Gellman, M., & Schneiderman, N. Cardiovascular response to stress and insulin metabolic syndrome in gestational diabetes mellitus. Annals of Behavioral Medicine 1998; 20 (Suppl.), S058. 119). Skyler JS, Gelfand RA, Kourides IA, for the Inhaled Insulin Phase II Study Group. A Three-Month Multicenter Clinical Trial of Therapy with Inhaled Human Insulin in Type 1 Diabetes Mellitus. Diabetologia 1998; 41(Suppl 1):A45. 120). Cefalu WT, Gelfand RA, Kourides IA, for the Inhaled Insulin Phase II Study Group. A Three-Month Multicenter Clinical Trial of Therapy with Inhaled Human Insulin in Type 2 Diabetes Mellitus. Diabetologia 1998; 41(Suppl 1):A226. 121). Berger S, Davidson MH, Kourides IA, Landschultz, Gelfand RA, for the Inhaled Insulin Phase II Study Group. Add-On Therapy with Inhaled Human Insulin in Type 2 Diabetic Patients Failing Oral Agents: Preliminary Results of A Multicenter Trial. Diabetologia 1998; 41(Suppl 1):A226. 122). Greenbaum CJ, Cuthbertson D, Krischer J, and the DPT-1 Study Group. Silent Type 1 Diabetes. Diabetes 1999; 48:(Suppl 1):A81. 123). Palmer J, Wei, Greenbaum C, Krischer J, Cuthbertson D, and the DPT-1 Study Group. The DPT-1 Intravenous Insulin Suppresses Endogenous Insulin Secretion But Causes Post-Prandial Glucose Intolerance. Diabetes 1999; 48:(Suppl 1):A295. 124). Yu L, Cuthbertson DD, Maclaren N, Jackson R, Eisenbarth GS, Krischer JP, and the DPT-1 Study Group. Expression of GAD65 or ICA 512 (IA-2) Autoantibodies Amongst Cytoplasmic ICA Positive Relatives is Associated with Eligibility for DPT-1. Diabetes 1999; 48:(Suppl 1):A214. 125). Chase P, Cuthbertson D, Dolan L, Kaufman F, Krischer J, Schatz D, White N, Wilson D, Wolfsdorf J, and the DPT-1 Study Group. First Phase Insulin Release (FPIR) During the Initial Intravenous Glucose Tolerance Test (IV-GTT) in the Diabetes Prevention Trial (DPT-1). Diabetes 1999; 48:(Suppl 1):A238-239. 126) Kaufman F, Cuthbertson D, Krischer J and the DPT-1 Study Group. HbA1c Corrlatated with Fasting and Postprandial Glucose Levels in Subjects in the Diabetes Prevention Trial-type 1 (DPT-1). Diabetes 2001; 50(Suppl 1) A96 127) Kaufman F, Rafkin-Mervis L, Ricker A, Wherrett D and the DPT-1 Study Group. Recruitment of Subjects into the Diabetes Prevention TrialType 1 (DPT-1):Strategies and Progress Report from 1994-2000. Diabetes 2001; 50(Suppl 1) A96 128) Skyler JS, for the Exubera Phase III Study Group. Efficacy and Safety of Inhaled Insulin (Exubera) Compared to Subcutaneous Insulin Therapy in an Intensive Insulin Regimen in Patients with Type 1 Diabetes: Results of a 6-month, Randomized, Comparative Trial. Diabetes 2002; 51(Suppl 2):A134. 129) Hernandez-Cassis CS, Hernandez CK, Solano MP, Marks JB, Skyler JS. The Oro-Enteric Phase of Insulin Secretion and the Effect of an Insulin Secretagogue in Subjects with Type 2 Diabetes Mellitus. Diabetes 2002; 51(Suppl 2):A568. 130) Skyler JS, for the Exubera Phase III Study Group. Efficacy and Safety of Inhaled Insulin (Exubera) Compared to Subcutaneous Insulin Therapy in an Intensive Insulin Regimen in Patients with Type 1 Diabetes: Results of a 6-month, Randomised, Comparative Trial. Diabetologia 2002; 45(Suppl 1):A17. 131) Prieto LM, Solano MP, Mintz DH, Skyler JS, Meneghini LF. Predicting Cardiac Autonomic Dysfunction in a Specialized Academic Diabetes Center. Diabetes 2003; 52(Suppl 1):A487. 132) Redondo MJ, Babu S, Zeidler A, Orban T, Yu L, Cuthbertson D, Eisenbarth GS, Krischer J, Schatz D. Diabetes Prevention Trial (DPT)-1: Influence of Protective HLA-DQ Alleles and Genotypes on Expression of Autoantibodies (Aab) and Progression to Type 1 Diabetes (T1DM). Diabetes 2004; 53(Suppl 1):A29(125-OR) 133) Sosenko JM, Greenbaum CJ, Palmer JP, Cowie CC, White NH, Cuthbertson DD, Krischer JP, Skyler JS, The DPT-1 Study Group. Fasting Insulin Secretion Is Maintained More Than Stimulated Insulin Secretion with Progression to Type 1 Diabetes (T1D) in the Diabetes Prevention TrialType 1 (DPT-1). Diabetes 2004; 53(Suppl 1):A425 (1783-P) 134) Skyler J, For The Exubera Phase II Study Group. Sustained Long-Term Efficacy and Safety of Inhaled Insulin during 4 Years of Continuous Therapy. Diabetes 2004; 53(Suppl 1):A115 (486-P) 135) Rhodes E, Wolfsdorf J, Feldman H, Ludwig D, DPT-1 Study Group. Effect of Low-Dose Insulin Treatment on Body Weight and Adiposity in Children at Risk of Type 1 Diabetes Mellitus. Diabetes 2004; 53(Suppl 1):A415 (1743-P) 136) Skyler J, For The Exubera Phase II Study Group. Long-term, sustained efficacy and safety of inhaled insulin after 4 years of continuous therapy. Diabetologia 2004; 47:(Suppl 1):P 863 137) Garcia C, Allende G, Matheson D, Marks J, Sanchez J, Skyler J, Mendez A, Pugliese A. Increased Proportions of Circulating Proins+ Peripheral Antigen Expressing (PAE) Cells in Type 1 Diabetes. Diabetes 2005; 54(Supplement 1): A79 (320-O). Jay S. Skyler Page 65 Curriculum Vitae 138) Sosenko JM, Palmer JP, Greenbaum CJ, Cowie CC, Mahon J, Chase HP, White NH, Cuthbertson DD, Krischer JP, Skyler JS, The DPT-1 Study Group. The 2-hr-Glucose and the AUC Glucose-AUC C-Peptide Ratio as Predictors of T1D in Diabetes Prevention Trial-Type 1 (DPT-1) Participants. Diabetes 2005; 54(Supplement 1): A456 (1897-P). 139) Barker JM, Babu S, Fernando M, Greenbaum C, Mahon J, Skyler JS, Eisenbarth GS, and the TrialNet study group. Low prevalence of DQA*0102 DQB*0602 subjects with Trialnet Initial Biochemical Autoantibody Screening. Diabetes 2006; 55:(Supplement): A251 (1061-P). 140) Lachin JM, Friedenberg P, Greenbaum C, and Type 1 Diabetes TrialNet. The Mixed Meal Tolerance Test versus the IV Glucagon Stimulation Test for the Assessment of Beta Cell Function in Type 1 Diabetes. Diabetes 2006; 55:(Supplement): A537 (2325-PO). 141) Skyler JS, Jovanovic L, Klioze S, Reis J, Duggan W. Sustained efficacy and tolerability of inhaled human insulin (Exubera®). Therapy over 2 years: patients with type 1 diabetes. Diabetologia 2006; 49:(Suppl 1): 118. 142) Skyler JS, Krasner A, Klioze S, Schwartz P, Duggan W. Body Weight Changes Associated With Insulin Therapy: A Retrospective Pooled Analysis of Inhaled Human Insulin (Exubera) Versus Subcutaneous Insulin in 5 Controlled Phase 3 Trials. Diabetic Medicine 2006; 23(suppl 4):958. 143) Hollander P, Skyler J, Jovanovic L, Klioze S, Krasner A, Riese R, Reis J, Schwartz P. Pulmonary Safety Following Discontinuation and Readministration of Inhaled Human Insulin (Exubera) in Adults with Type 1 Diabetes. Diabetes 2007; 56:(Supplement 1): A125-126 (Abstract 472P). 144) Sosenko JM, Krischer JP, Palmer JP, Mahon J, Cowie C, Greenbaum CJ, Cuthbertson DD, Lachin J, Skyler JS, and the DPT-1 Study Group. A Risk Score for Type 1 Diabetes Derived from Participants in the Diabetes Prevention Trial-Type 1 (DPT-1). Diabetes 2007; 56:(Supplement 1): A-55 (Abstract 210-0) 145) Herold KC, for the Type 1 Diabetes TrialNet Study Group, the TrialNet Study Group Mechanistic Assay Committee, and the TrialNet T-Cell Assay Group. Report of the TrialNet T-Cell Validation Study in Type 1 Diabetes. Diabetes 2007; 56:(Supplement 1): A-319 (Abstract 1299-P) 146) Mari A, Ferrannini E, Skyler JS, and the DPT-1 Study Group. Mechanisms of Progression to Diabetes in Relatives of Type 1 Diabetic Patients. Diabetes 2007; 56:(Supplement 1): A-384 (Abstract 1499-P) 147) Sosenko JM, Wherrett D, Rafkin-Mervis L, Palmer JP, Skyler JS, and the DPT-1 Study Group. Metabolic Characteristics of Converters to ICA Positivity in the Diabetes Prevention Trial-Type 1 (DPT-1). Diabetes 2007; 56:(Supplement 1): A-482 (Abstract 1907-P) 148) Mahon J, Sosenko J, Lachin J, Krause-Steinrauf H, Rafkin-Mervis L, Eisenbarth G, Palmer J, Thompson C, Skyler J,for the Type 1 Diabetes TrialNet Study Group. The Prevalence of Glucose Tolerance Abnormalities According to Autoantibody Number in the Type 1 Diabetes TrialNet Natural History Study. Diabetes 2007; 56:(Supplement 1): A-486 (Abstract 1922-P) 149) Chase HP, Asare S, Greenbaum C, Lachin J, Lescheck E, Krause-Steinrauf H, Rafkin-Mervis L, Clare-Salzler M, for the Type 1 Diabetes TrialNet NIP Study Group. Nutritional Intervention to Prevent (NIP) Type 1 Diabetes. Diabetes 2007; 56:(Supplement 1): A-689 (Abstract 2723-PO) 150) Krischer JP for the Type 1 Diabetes TrialNet Oral Insulin Study Group. Oral Insulin For the Prevention Of Diabetes In Relatives At Risk For Type 1 Diabetes Mellitus (T1DM). Diabetes 2007; 56:(Supplement 1): A-699 (Abstract 2764-PO) 151) Skyler J, Hollander P, Jovanovic L, Klioze S, Krasner A, Riese R, Reis J, Schwartz P. Discontinuation and readministration of inhaled human insulin (Exubera®) in adults with type 1 diabetes: 3-year pulmonary safety data. Diabetologia 2007; 50:(Supplement 1): S-400-401. 152) Mahon J, Sosenko JM, Lachin J, Krause-Steinrauf H, Rafkin-Mervis L, Eisenbarth GS, Palmer JP, Thompson C, and The Type 1 Diabetes TrialNet Study Group. The Prevalence of Glucose Tolerance Abnormalities According to Autoantibody Number in the Type 1 Diabetes TrialNet Natural History Study. Acta Diabetologia 2007; 44:(Supplement 1): S 30. 153) Herold K for the Mechanistic Outcomes Committee and the Type 1 Diabetes TrialNet Study Group. Report from TrialNet: Diagnostic Accuracy and Reproducibility of T-Cell Responses to Islet Antigens in Subjects with Recently Diagnosed Type 1 Diabetes. Acta Diabetologia 2007; 44:(Supplement 1): S 21. 154) Sosenko JM, Rafkin-Mervis L, Mahon J, Lachin J, Krause-Steinrauf H, Krischer J, Cuthbertson D, Palmer JP, Skyler JS, and the DPT-1 and Type 1 Diabetes TrialNet Study Groups. Comparison Between Participants of the TrialNet Natural History Study and Participants of the Diabetes prevention Trial-Type 1. Acta Diabetologia 2007; 44:(Supplement 1): S 50. 155) Sosenko JM, Palmer JP, Rafkin-Mervis L, Krischer J, Cuthbertson D, Matheson D, Skyler JS, and the DPT-1 Study Group. Glucose and CPeptide Changes in the Peri-onset Period of Type 1 Diabetes in the Diabetes Prevention Trial – Type 1 (DPT-1). Acta Diabetologia 2007; 44:(Supplement 1): S 49-50. 156) Ferrannini E, Nofrate V, Skyler JS, Mari A, for the DPT-1 Study Group. Progression to diabetes in relatives of people with type 1 diabetes: predictors and mode of onset. Diabetes 2008; 57:(Supplement 1): A-45 (Abstract 150-OR). 157) Sosenko JM, Rafkin-Mervis L, Mahon J, Lachin J, Krause-Steinrauf H, Krischer J, Cuthbertson D, Palmer JP, Thompson C, Skyler JS, and the Diabetes Prevention Trial-Type 1 Diabetes (DPT-1) and Type 1 Diabetes TrialNet Study Groups. Comparisons of OGTT Indices between Participants of the TrialNet Natural History Study and Participants of the Diabetes Prevention Trial-Type 1. Diabetes 2008; 57:(Supplement 1): A-264 (Abstract 914-P). Jay S. Skyler Page 66 Curriculum Vitae 158) Sosenko JM, Palmer JP, Rafkin-Mervis L, Krischer J, Cuthbertson D, Skyler JS, and the DPT-1 Study Group. Incident Post-Challenge Dysglycemia as a Predictor of Type 1 Diabetes in the Diabetes Prevention Trial-Type 1 (DPT-1). Diabetes 2008; 57:(Supplement 1): A-66 (Abstract 228-OR). 159) Sosenko JM, Palmer JP, Rafkin-Mervis L, Krischer J, Cuthbertson D, Matheson D, Skyler JS, and the DPT-1 Study Group. The Loss of PostChallenge C-Peptide Levels in the Peri-Onset Period of Type 1 Diabetes in the Diabetes Prevention Trial-Type 1 (DPT-1). Diabetes 2008; 57:(Supplement 1): A-502 (Abstract 1810). 160) Triolo TM, Chase HP, Barker JM, and the DPT-1 Study Group. Subjects Diagnosed with Diabetes through the Diabetes Prevention Trial Type 1 (DPT-1) are Often Asymptomatic and Have Rare Ketosis at Onset. Diabetes 2008; 57:(Supplement 1): A-501-502 (Abstract 1807). 161) Hernandez-Cassis C, Casanova-Romero P, Florez H, Gomez O, Skyler JS. The four time-point oral glucose tolerance test, the predictive value of 30 and 60 minutes for diagnosis of impaired glucose tolerance and type 2 diabetes mellitus. Endocrine Society Proceedings 2008. 162) Sosenko J, Palmer J, Rafkin-Mervis L, Krischer J, Cuthbertson D, Greenbaum C, Skyler JS, The DPT-1 Study Group. The Timing of the Peak CPeptide and Its Prediction of Type 1 Diabetes in the Diabetes Prevention Trial-Type 1 (DPT-1). Diabetes 2009; 58: (Supplement 1): Abstract 22-OR. 163) Pescovitz MD, Torgerson TR, Ochs HD, Ocheltree E, Mcgee P, Krause-Steinrauf H, for the Type 1 Diabetes Trial Network (TrialNet). In Vivo Immune Responses in Type 1 Diabetes Following Treatment with Rituximab. Diabetes 2009; 58: (Supplement 1): Abstract 195-OR. 164) Jeffrey J, Eisenbarth GS, Fain PR, Yu L, Miao D. Persistent but Not Transient Biochemical Islet Autoantibody Expression Is Increased in Prospectively Followed Monozygotic Versus Dizygotic Twins. Diabetes 2009; 58: (Supplement 1): Abstract 1141-P. 165) Sosenko J, Palmer J, Rafkin-Mervis L, Krischer J, Cuthbertson D, Greenbaum C, Skyler JS, The DPT-1 Study Group. Trends of Earlier and Later C-Peptide Responses to Oral Glucose with Progression to Type 1 Diabetes in the Diabetes Prevention Trial-Type 1 (DPT-1). Diabetes 2009; 58: (Supplement 1): Abstract 1801-P. 166) Gottlieb P, Colman PG, Kipnes M, Ratner R, Aroda V, Rendell M, Gerstman M, Zemel L, Dunn P, Hays R, Heazlewood V, Baker J, Scott R, Davis T, Greenbaum C, Krebs J, Norwood P, Ovalle F, Raskin P, Skyler JS, Quan J, Solvason N, Roep B, Harrison LC, Eisenbarth G, Steinman L, Garren H. Interim Results of a Phase I/II Clinical Trial of a DNA Plasmid Vaccine (BHT-3021) for Type 1 Diabetes. Diabetes 2009; 58: (Supplement 1): Abstract 114-OR. 167) Vehik K, Haller MJ, Xu P, Schatz DA, Krischer J, DPT-1 Study Group. Seroconversion in the DPT-1 Study: evidence of triggering of autoimmune process at different ages. Diabetologia 2009; 52:(Supplement 1)S 119 (Abstract 277). 168) Pescovitz MD, McGee P, Krause-Steinrauf H, Canniff J, Weinberg A, Skyler JS, and Type 1 Diabetes TrialNet Study Group. Human in vivo De Novo and Recall Antibody Responses after Rituximab Treatment for Type 1 Diabetes. FOCiS 2010. 169) Vehik K, Beam CA, Haller MJ, Sosenko JM, Schatz DA, Mahon JL, Krischer JP, Skyler JS, for the Type 1 Diabetes TrialNet Study Group. Development of Autoantibodies in the TrialNet Natural History Study. Diabetes 2010; 53:(Supplement 1): Abstract 213-OR. 170) Ferrannini E, Mari A, Nofrate V, Krischer JP, Sosenko JM, Skyler JS, for the DPT-1 Study Group. Prediction of Diabetes in Relatives of People with Type 1 Diabetes: Role of Clinical Testing. Diabetes 2010; 53:(Supplement 1): Abstract 236-OR. 171) Sosenko JM, Skyler JS, Krischer JP, Greenbaum CJ, Rafkin-Mervis L, Mahon J, Cuthbertson D, Palmer JP, and The DPT-1 Study Group. Transient Diabetic Range Oral Glucose Tolerance Tests and Their Possible Relation to Insulin Sensitivity Prior to the Diagnosis of Type 1 Diabetes in the Diabetes Prevention Trial Type-1 (DPT-1). Diabetes 2010; 53:(Supplement 1): Abstract 172) Sosenko JM, Skyler JS, Palmer JP, Krischer JP, Cuthbertson D, Yu L, Schatz DA, Orban T, Eisenbarth GS, and The DPT-1 Study Group. Quantitative Changes in ICA512 and GAD65 Autoantibodies with Progression to Type 1 Diabetes in the Diabetes Prevention Trial-Type 1 (DPT-1). Diabetes 2010; 53:(Supplement 1): Abstract 68-OR. 173) Chase HP, Boulware D, Krischer JP, Daniels M, Nathan B, Chritton S, Muller S, Clare-Salzler M, and the TrialNet Nutritional Intervention to Prevent (NIP) Diabetes Study Group. Vitamin D and Inflammatory Cytokine Levels in Infants at High Genetic Risk for Type 1 Diabetes. Diabetes 2010; 53:(Supplement 1): Abstract 174) Chase HP, Boulware D, Krischer JP, Rodriguez H, Donaldson D, Chritton S, Muller S, Clare-Salzler M, and the TrialNet Nutritional Intervention to Prevent (NIP) Diabetes Study Group. Inflammatory Cytokines in the Pre-Autoimmune Phase of Type 1 Diabetes. Diabetes 2010; 53:(Supplement 1): Abstract 175) Pescovitz MD, Krischer JP, Bundy B, Rodriguez H, Greenbaum CJ, Skyler JS, and The Type 1 Diabetes TrialNet Anti-CD20 Study Group. Preservation of beta-cell function by B-lymphocyte depletion with rituximab- 2-year results. Diabetes 2010; 53:(Supplement 1): Abstract 176) Gottlieb P, Colman PG, Solvason N, Otto K, Roep B, Harrison LC, Eisenbarth G, Robinson W, Utz PJ, Steinman L, Garren H, Quan J, for the BHT-3021 Study Group. One-Year Results from a Phase 1/2 Clinical Trial of BHT-3021, a DNA Plasmid Vaccine for Type 1 Diabetes. Diabetes 2010; 53:(Supplement 1): Abstract 177) Sosenko J, Skyler J, Mahon J, Krischer J, Greenbaum C, Rafkin L, Beam C, Boulware D, Matheson D, Cuthbertson D, Eisenbarth G, Palmer J, Diabetes Prevention Trial-Type 1/TrialNet Study Groups. The Use of the Diabetes Prevention Trial-Type 1 Risk Score (DPTRS) for Identifying Normoglycemic Subjects at High Risk for Type 1 Diabetes. Diabetes 2011; 60: (Suppl 1): Abstract 0158-OR. Jay S. Skyler Page 67 Curriculum Vitae 178) Yu L, Mahon J, Boulware D, Hutton J, Wenzlau J, Greenbaum C, Bingley P, Beam C, Krischer J, Sosenko J, Eisenbarth G, for the Type 1 Diabetes TrialNet Study Group. Zinc Transporter 8 Autoantibodies and Diabetes Risk in the TrialNet Natural History Study. Diabetes 2011; 60: (Suppl 1): Abstract 0260-OR. 179) Long SA, Sanda S, Buckner JH, Bollyky JB, Goland R, Bianchine P, Phippard D, Ehlers M, Greenbaum C, ITN and TrialNet Study Groups. Rapamycin Plus IL-2 Combination Therapy in Subjects with T1D Results in a Sustained Increase in IL-2 Responsiveness and a Transient Decrease in C-Peptide Levels. Diabetes 2011; 60: (Suppl 1): Abstract 0332-OR. 180) McGee P, Krause-Steinrauf H, Greenbaum C, Pescovitz M, Herold K, Spain LM, Palmer JP, Skyler JS, and Lachin JM, for the Type 1 Diabetes TrialNet Study Group. Selection of a Biological Response Criterion for Evaluation of Treatment Efficacy in Trials of New-Onset Type 1 Diabetes. Diabetes 2011; 60: (Suppl 1): Abstract 437-P. 181) Johnson SB, Rafkin LE, Boulware D, Pescovitz M, and the Type 1 Diabetes TrialNet Study Group. Participant and Parent Experiences in a Rituximab Trial to Preserve Beta Cell Function. Diabetes 2011; 60: (Suppl 1): Abstract 848-P. 182) Buckingham B, Buckingham J, Uttarwar A, Slover R, Messer L, Xing, D, Ruedy K, for the DirecNet and TrialNet Study Groups. The Accuracy of the GlucoScout ® Blood Glucose Monitor in Inpatient Monitoring of Patients with Type 1 Diabetes. Diabetes 2011; 60: (Suppl 1): Abstract 0869-P 183) Buckingham B, Wilson D, Weinzimer S, Sherr J, Block J, Slover R, Chase P, Cantwell M, DiMeglio L, Bremer A, Ruedy K, Xing, D, and DirecNet and Type 1 Diabetes TrialNet Study Groups. Use of A Hybrid Closed-Loop to Restore Metabolic Control at the Onset Of Diabetes. Diabetes 2011; 60: (Suppl 1): Abstract 0873-P 184) Sosenko J, Skyler J, Mahon J, Krischer J, Greenbaum C, Rafkin L, Matheson D, Cowie C, Beam C, Boulware D, Cuthbertson D, Palmer J, Diabetes Prevention Trial-Type 1/TrialNet Study Groups. The OGTT Index as an Indicator of the pre-Diabetic State of Type 1 Diabetes in Children. Diabetes 2011; 60: (Suppl 1): Abstract 1214-P. 185) Vehik K, Beam CA, Boulware D, Schatz DA, Krischer JP, and Type 1 Diabetes TrialNet Study Group. Autoantibody Reversion in the TrialNet Natural History Study. Diabetes 2011; 60: (Suppl 1): Abstract 1286-P. 186) Jeffrey J, Yu L, Steck AK, Hays B, Eisenbarth GS, Fain PK, and Type 1 Diabetes TrialNet Study Group. Transient Autoantibody Positivity in TrialNet Twins. Diabetes 2011; 60: (Suppl 1): Abstract 1394-P. 187) Wherrett DK, for Type 1 Diabetes TrialNet Study Group. Rapid Enrollment to GAD65-Alum Trial in Recent-Onset Type 1 Diabetes Including Subjects as Young as Age 3. Diabetes 2011; 60: (Suppl 1): Abstract 2542-PO. 188) Faleo G, Fotino C, Bocca N, Molano RD, Zahr-Akrawi E, Molina J, Villate S, Umland O, Bayer AL, Skyler JS, Ricordi C, Pileggi A. Prevention of Autoimmune Diabetes and Induction of β-Cell Proliferation in NOD Mice by Hyperbaric Oxygen Therapy. Diabetes 2011; 60: (Suppl 1): Abstract 1470-P. 189) Buse JB, Garg SK, Skyler JS, Vaughn DE, Muchmore DB. Comparison of Human Hyaluronidase + Recombinant Human Insulin (RHI) vs. Insulin Lispro in a Basal-Bolus Regimen in Patients with Type 1 Diabetes (T1DM). Diabetes 2011; 60: (Suppl 1): Abstract 0069-OR 190) Garg SK, McGill JB, Rosenstock J, Hirsch IB, Petrucci RE, Chang P-C, Boss AH, Richardson PC, Skyler JS. Technosphere® Insulin vs Insulin Lispro in Patients with Type 1 Diabetes Using Multiple Daily Injections. Diabetes 2011; 60: (Suppl 1): Abstract 0917-P. 191) Buckingham BA, Slover RH, Weinzimer SA, Dimeglio LA, Bremer A, Cantwell M, Xing D, Ruedy K, Diabetes Research In Children Network (DIRECNET), TrialNet Study Group. Effect of a Hybrid Closed-Loop (HCL) on Restoring Metabolic Control at the Onset of Diabetes. Diabetes 2012; 61: (Suppl 1): Abstract 891-P. 192) Pugliese A, Boulware D, Babu S, Steck AK, Beam CA, Becker DJ, Eisenbarth GS, Greenbaum C, and The Type 1 Diabetes TrialNet Study Group. The HLA-DR2, DQB1*0602 Haplotype is Associated with Lack of Disease Progression and Lower Autoantibody Prevalence in the TrialNet Natural History Study. Diabetes 2012; 61: (Suppl 1): Abstract 360-OR. 193) Orban T, Type 1 Diabetes TrialNet Abatacept Study Group. Co-Stimulation Modulation with Abatacept in Patients with Recent-Onset Type 1 Diabetes; A Follow up Study at 3 Years. Diabetes 2012; 61: (Suppl 1): Abstract 150-LB. 194) Sosenko J, Skyler J, Eisenbarth GS, Krischer J, Yu L, Mahon J, Beam CA, Boulware D, Rafkin L, Schatz DA, Palmer J, Type 1 Diabetes TrialNet Study Group. The Prediction of Type 1 Diabetes by Multiple Autoantibody Levels and Their Incorporation into an Autoantibody Risk Score in the TrialNet Natural History Study. Diabetes 2012; 61: (Suppl 1): Abstract 202-OR. 195) Sosenko J, Skyler J, Krischer J, Herold KC, Greenbaum C, Rafkin L, Cuthbertson D, Palmer J, Diabetes Prevention Trial-Type 1 Study Group, Type 1 Diabetes TrialNet Study Group. Characteristic Insulin Secretion Patterns Persist at the Diagnosis of Type 1 Diabetes in the Diabetes Prevention Trial-Type 1 (DPT-1). Diabetes 2012; 61: (Suppl 1): Abstract 1256-P. 196) Beam CA, Gitelman SE, Herold KC, Krischer J, Type 1 Diabetes TrialNet Study Group. Diabetes 2012; 61: (Suppl 1): Abstract 2368-PO. 197) Hirsch IB, Skyler J, Garg S, Blevins T, Vaughn DE, Muchmore DB. Human Hyaluronidase + Rapid Analog Insulin (RAI) Improves Postprandial Glycemic Control in Type 1 Diabetes Compared to Insulin Lispro Alone. Diabetes 2012; 61: (Suppl 1): Abstract 353-OR. 198) Skyler J, Garg S, Hirsch IB, Blevins T, Vaughn DE, Muchmore DB. Human Hyaluronidase + Rapid Analog Insulin (RAI) Improves Postprandial Glycemic Control in Type 1 Diabetes Compared to Insulin Lispro Alone. Diabetologia 2012; 55: (Suppl 1): Abstarct 41, pages S22-S23. Jay S. Skyler Page 68 Curriculum Vitae 199) Sosenko JM, Skyler JS, Dimeglio LA, Krischer JP, Beam CA, Rafkin L, Matheson D, Palmer JP, Diabetes Prevention Trial-Type 1 and TrialNet. A Potential New Diagnostic Index for Type 1 Diabetes. Diabetes 2013; 62: (Suppl 1): Abstract 1316-P 200) Sosenko JM, Skyler JS, Krischer JP, Beam CA, Rafkin L, Palmer JP, Diabetes Prevention Trial-Type 1 and TrialNet. The Loss of the First-Phase Insulin Response (FPIR) Accelerates During the Progression to Type 1 Diabetes. Diabetes 2013; 62: (Suppl 1): Abstract 352-OR 201) Boyle P, Boniol M, Koechlin A, Bota M, Robertson C, Pizot C, Skyler J, Bolli GB, Rosenstock J, Autier P. Safety of Glucose-Lowering Medications: The Diabetes Adverse Event Monitor (DIABAMON) Project: II Cardiovascular Disease. Diabetes 2013; 62: (Suppl 1): Abstract 1405-P 202) Fotino C, Faleo G, Molano RD, Bocca N, Zahr-Akrawi E, Skyler J, Ricordi C, Bayer AL, Pileggi A. Anti-CD3 and Hyperbaric Oxygen Therapy (HOT) to Halt Autoimmune Diabetes Onset in NOD Mice. Diabetes 2013; 62: (Suppl 1): Abstract 1705-P 203) Pugliese A, Boulware D, Babu S, Marks JB, Schatz DA, Dimeglio LA, Harrison LC, Greenbaum C, Becker DJ, Steck AK, Rodriguez H, and The Type 1 Diabetes TrialNet Study Group. The High Risk HLA DR4-DQB1*03:02 Haplotype is Associated with Increased Progression to T1D in Relatives with a Single Autoantibody Specificity. Diabetes 2013; 62: (Suppl 1): Abstract 128-OR 204) Pugliese A, Skyler J, Palmer J, Beam C, Boulware D, Sosenko J, TrialNet and Diabetes Prevention Trial-Type 1 Study Groups. The Influence of the DQB1*0602 Allele on Predictors of Type 1 Diabetes (T1D) in the TrialNet Natural History Study TNNHS). Diabetes 2014; 63: (Suppl 1): Abstract 26-OR 205) Sosenko J, Skyler J, Beam C, Boulware D, Mahon J, Krischer J, Greenbaum C, Rafkin L, Matheson D, Palmer J, TrialNet and Diabetes Prevention Trial Type 1 Study Groups. A Progression Scale for Assessing the Change in Glucose over 6 Months in Individuals at Risk for Type 1 Diabetes (T1D). Diabetes 2014; 63: (Suppl 1): Abstract 1221-P 206) DiMeglio LA, Cheng P, Beck R, Kollman C, Ruedy K, Buckingham B, Weinzimer S, Slover R, Bremer A, Aye T for the DirecNet and TrialNet Study Groups. Early Predictors of Stimulated C-peptide in Persons with Type 1 Diabetes (T1D). Diabetes 2014; 63: (Suppl 1): Abstract 1503-P 207) Buckingham B, Cheng P, Beck R, Kollman C, Ruedy K, Weinzimer S, Slover R, Bremer A, Tamborlane W, Fuqua J for the DirecNet and TrialNet Study Groups. Relationship of Glycemic Control and C-peptide Levels 2 Years Following Diagnosis of T1D. Diabetes 2014; 63: (Suppl 1): Abstract 1504-P 208) Chaudhry ZZ, Watkins RA, Beam C, Guindon L, Mirmira RG, Blum J, DiMeglio L, Evans-Molina C, and the Type 1 Diabetes TrialNet Study Group. The Proinsulin/C-peptide Ratio and HSP90: Potential Biomarkers for Early Detection of Type 1 Diabetes. American Diabetes Association 74th Annual Meeting 2014; Late Breaking Abstract 149-LB. 209) Pugliese A, Boulware D, Beam C, Babu S, Marks J, Schatz D, DiMeglio L, Evans-Molina C, Harrison L, Greenbaum C, Becker D, Steck A, Rodriguez H, and the Type 1 Diabetes TrialNet Study Group. HLA-DRB1-DQB1 Haplotypes/Genotypes Influence Progression to Type 1 Diabetes (T1D) in Autoantibody-Positive Relatives. Diabetes 2014; 63: (Suppl 1): Abstract 271-OR 210) Skyler JS, Fonseca V, Rosenstock J, for the MSB-DM003 Investigators. Effects of Allogeneic Mesenchymal Precursor Cells in Type 2 Diabetes: A Randomized, Placebo-Controlled Study. American Diabetes Association 74th Annual Meeting 2014; Late Breaking Abstract 123-LB. 211) Skyler JS, Bode B, Hirsch IH, Buse JB, Garg SK, Vaughn DE, Wu XY, Muchmore DB. Recombinant human hyaluronidase pretreatment of CSII cannula sites provides comparable glycaemic control with reduced hypoglycaemia in T1DM compared to usual CSII. Diabetologia 2014; 57: Supplement: S70 (abstract 149). 212) Bizzotto R, Hurwitz BE, Schneiderman N, Marks JB, Mendez AJ, Gonzalez A, Gonzalez N, Llabre MM, Santini E, Skyler JS, Mari A, Ferrannini E. Adaptation of beta cell response to carbohydrate loading: influence of insulin resistance. Diabetologia 2014; 57: Supplement: S210 (abstract 504). 213) Sosenko JM, Skyler JS, Pugliese A, Krischer JP, Greenbaum CJ, Boulware D, Rafkin L, Palmer JP, Type 1 Diabetes Trialnet Study Group. Abnormal Glucose Tolerance in Young, Non-Obese Autoantibody Negative Relatives of Patients with Type 1 Diabetes (T1D). Diabetes 2015; 64(Suppl 1):Abstract 358-OR, page A93. 214) Davies JD, Robertson HK, Moya R, Koziol J and the TrialNet Type 1 Diabetes Study Group. CD25 Expression on Non-Treg CD4+ T Cells is Associated with Duration of the Honeymoon Period in Children with Type 1 Diabetes. Diabetes 2015; 64(Suppl 1):Abstract 229-O, page A60. 215) Bayer AL, Lanzoni G, Umland O, Agostini L, Skyler JS, Matheson D, Inverardi L, Fraker C. Innate Immunity Inhibition in Type 1 Diabetes: Latent Viral Hypothesis in he Etiology of Autoimmunity. Diabetes 2015; 64(Suppl 1):Abstract 1836-P, page A474. 216) Jossan P, Zaitlen N, Sanda S; for the Type 1 Diabetes TrialNet Study Group. Clinical and Genetic Predictors of Residual Insulin Secretion in New-Onset Type 1 Diabetes. Diabetes 2015; 64(Suppl 1):Abstract 1741-P, page A452. 217) Fouts A, Pyle L, Yu L, Miao D, Michels A, Krischer J, Sosenko J, Gottlieb P, Steck AK and the Type 1 Diabetes TrialNet Study Group. Factors Involved in Predicting Time to Type 1 Diabetes in Antibody Positive TrialNet Subjects. Diabetes 2015; 64(Suppl 1):Abstract 1722-P, page A447. 218) Sosenko JM, Yu L, Skyler JS,Steck A, Gottlieb PA, Boulware D, Palmer JP, Diabetes Type 1TrialNet Study Group. Electrochemiluminescence (ECL) Assays for Predicting Progression to Type 1 Diabetes (T1D) in Single-Autoantibody-Positive Individuals. Diabetes 2015; 64(Suppl 1):Abstract 2649-PO, page A669. 219) DiMeglio L. Who is not Returning? Retention of Recruited Subjects in the Type 1 Diabetes TrialNet Pathway to Prevention (PTP). American Diabetes Association 75th Annual Meeting 2015; Late Breaking Abstract 187-LB. Jay S. Skyler Page 69 Curriculum Vitae 220) Meah F, Xu P, DiMeglio LA, Sosenko JM, Geyer S, Evans-Molina C, and the Type 1 Diabetes TrialNet Study Group. HOMA2beta is Predictive of the Development of Type 1 Diabetes in TrialNet Pathway to Prevention Participants. American Diabetes Association 75th Annual Meeting 2015; Late Breaking Abstract 145-LB.