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Date: February 16th, 2017 Aim # 51: How can mitosis lead to a Do Now: 1) What is interphase? How much of the cell cycle is spent during this stage? 2) What does PMAT stand for? 3) What is cytokinesis? How does it differ in plant and animal cells? HW: 1)Daily Review of Class Notes 2)All Labs due Friday Aim#51: How can mitosis lead to a disruption in homeostasis? What could have caused this? Cancer Approximately 200 types Lung cancer Skin cancer Breast cancer Can you think of some? Prostate cancer 1) Healthy cells • Grow, divide, and replace themselves during the process of mitosis. Each mitotic division leads to the development of 2 NEW healthy cells. How do cells divide by mitosis? 2) Abnormal cell division • Sometimes, normal cells lose their ability to limit and direct their growth. They divide too rapidly and grow without any order. 3) What happens if cells are unable to regulate the cell cycle? Cancer is a disease that is caused by loss of control of the cell cycle (uncontrolled cell division). Cells continue to divide uncontrollably. 4) What are tumors? • Tumors (lumps or masses of cancerous cells) will form as a result of this uncontrolled cell division. • Tumors can be either malignant (spread dangerous) or benign (can’t spread – safe) Metastasis They spread by using the circulatory system and lymph nodes. Cancer cells also can spread, to other parts of the body and form new tumors. How do they spread? 7) What causes cancer? •Damage to the cells DNA from: • Mutations - to genes, the •Poor Diet for making cell's instructions the proteins it needs to •Certain Pathogens survive, grow and multiply.(Viruses) • Ultraviolet radiation •Genetics • Viruses • •UV Usually cancer is not Radiation (Sun) inherited • •Drugs Carcinogens: chemicals (Tobacco) Anatomy of a Cigarette • Smoking causes a third of all cases of cancer • Cigarette smoke contains 3000 different chemicals, some of which are carcinogens. Some people have a lower risk of developing lung cancer. Their cells may be more efficient at repairing the gene damage caused by the carcinogens. Lung Cancer: Healthy Lung Cancerous Lung What is “x”? 8) Treatment • Surgery: physical removal of the malignant tumor • Radiation: disrupts cell division • Chemotherapy: drugs that prevent cell division by interfering with mitosis Amoeba Sisters Cell Cycle and Cancer https://www.youtube.com/watch?v=lpAa4TWjHQ4