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WORKSHEET: Stages of a Cell Cycle ANSWER KEY PART 1: Matching Match the statements in column A, with the five phases of mitosis in column B. Write the letter of the response in the blank on the left side. A B D 1. Nucleolus appears within each new nucleus. A. Prophase C 2. Centromeres divide. B. Metaphase A 3. Chromosomes become visible. C. Anaphase A 4. Spindle fibres begin to form. D. Telophase E 5. DNA replicates E. Interphase C 6. Replicated strands move toward opposite poles. B 7. Chromosomes form a line across the middle of the cell. D 8. Nuclear envelope forms around each set of chromosomes. E 9. Cell grows. A 10. Centrioles move to opposite ends of the cell. C 11. Chromosome strands separate toward opposite ends of the cell. A 12. Nuclear envelope disappears. D 13. Cell membrane pinches together and the cytoplasm of the cell divides. D 14. Daughter cells form. E 15. It makes up most of a cell’s life. PART 2: Completing the Chart Place a check mark under each phase in which you can see the structures listed in the first column. Structures Present Interphase Prophase Metaphase Anaphase Telophase Nucleus Nucleolus Nuclear membrane Chromatin Chromosomes Spindle fibres PART 3: Short Answer Complete these questions in your notebooks. 1. During which mitotic phase do chromosomes arrive and line up at the equator of the cell? Metaphase 2. What are the main events of prophase? Chromosomes condense (shorten and thicken) Centrioles have duplicated and start to more to opposite poles of the cell Spindle fibres form radiating out from the centrioles Spindle fibres attach to the centromere of the chromosome The nuclear envelope starts to disintegrates 3. What marks the beginning of telophase? Sister chromatids are pulled to opposite poles of the cell. 4. Of what are centrioles and spindle fibres made? Part of the cytoskeleton. 5. By what structures are chromatids attached to each other during prophase, metaphase, and anaphase? Chromatids are attached to spindle fibres. 6. Suppose the cell shown in interphase has 24 chromosomes before DNA replication. How many chromosomes does each of the two cells forming in telophase have? 24 chromosomes 7. When mitotic cells were first observed, why were interphase cells thought to be resting? What events have been found to occur during interphase? Cell activity can not be seen under the microscope. DNA is replicated during interphase. 8. (a) In mitosis, how many cells form from the original cell? Two (b) What are they called? Daughter cells