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By: Mark Garcia 1. An / Ana 4 2. Ase 5 3. Cat / Cata 6 4. Cis 6 5. Co 7 6. Eu 7 7. Hydro 8 8. Hyper 9 9. Hypo 10 10. Ic 10 11. Iso 11 12. Karyote 12 13. Lysis 12 14. Macro 13 15. Mer 13 16. Meta/Metabol 14 17. Micro 14 18. Mono 14 19. Ose 15 20. Peptide 15 21. Philic 16 22. Phobic 16 23. Photo 16 24. Polar 17 25. Poly 17 26. Pro 18 27. Saccharide 18 28. Synthesis 18 29. Tonic/Tonicity 19 30. Trans 19 31. Valence 20 1. An / Ana Root, Prefix or Suffix: Prefix Origin: Greek Literal Translation: Up, Upwards Example: Anion - any atom (ion) that has acquired at least one additional electron (the number of electrons has gone up). (Figure 1) Anabolic Process - process used by organisms to build up more complex structures from simpler ones. Figure 1. Electron exchange between sodium and chlorine results in the formation of sodium and chloride ions. Here, the chloride ion is classified as the anion. 2. Ase Root, Prefix or Suffix: Suffix Origin: French & Greek Literal Translation: A suffix used in the names of enzymes Example: Lactase - the enzyme involved in the metabolism of the sugar lactose. (Figure 2) Enzyme Function Amylase Catalyzes the metabolism of starch into smaller subunits ATP Synthase Uses the exergonic flow of H+ to drive phosphorylation of ATP Dehydrogenase Oxidizes a substrate by facilitating the removal of hydrogens from it DNA Polymerase Involved in the elongation of DNA polymers that occurs during the process of DNA replication Helicase Involved in the “unwinding” of the double helical structure of nucleic acids Hexokinase Phosphorylates a sugar that contains six-carbons Isomerase Assists with the transformation, structurally, of isomers Lactase Involved in the metabolism of the sugar lactose Maltase Involved in the metabolism of the sugar maltose Protease Used in the catabolism of various proteins RNA Polymerase Involved in the elongation of RNA polymers that occurs during the process of transcription Sucrase Involved in the metabolism of the sugar sucrose Figure 2. While not all enzymes end in “ase,” typically any term in a biological context that ends in “ase” describes a molecule that is classified as an enzyme. 3. Cat / Cata Root, Prefix or Suffix: Prefix Origin: Greek Literal Translation: Down, Downwards Example: Cation - any atom (ion) that has lost at least one additional electron (the number of electrons has gone down). (Figure 3) Figure 3. Electron exchange between sodium and chlorine results in the formation of sodium and chloride ions. Here, the sodium ion is classified as the cation. Catabolic Process - process used by organisms to break down more complex structures into simpler ones. 4. Cis Root, Prefix or Suffix: Prefix Origin: Latin Literal Translation: On the Near Side of Example: Can be used to denote the spatial arrangement of a geometric isomer wherein the atom(s) of interest that are attached to either of the carbons lie on the same (near) side of the isomer. (Figure 4) Figure 4. Geometric isomer in the cis orientation. 5. Co Root, Prefix or Suffix: Prefix Origin: Latin Literal Translation: Together Example: Covalent bond - a bond between atoms where the electrons in the valence shell of each atom are shared to give each atom a full valence. (The valence electrons between the two atoms are counted together so that both atoms appear to have full valences). (Figure 5) Figure 5. Polar Covalent Bonds between Oxygen & Hydrogen in a Water Molecule 6. Eu Root, Prefix or Suffix: Prefix Origin: Greek Literal Translation: Good, Well, True, Genuine Example: Eukaryote / Eukaryotic - An organism that has cells with membrane bound organelles, and genetic material that is housed in a nucleus. Karyote actually translates to nut or kernel (in this case that can be taken to mean that the nucleus acts as the kernel of the cell). So, the term literally translates to a cell or organism that has a genuine nucleus. 7. Hydro Root, Prefix or Suffix: Prefix Origin: Greek Literal Translation: Water; Presence of Hydrogen Example: Hydrophobic - Describes any substance or molecule that is afraid of water. Hydrolysis - Chemical reaction where a water is split as a means of catabolizing a compound. (Figure 6) Figure 6. A larger polymer is catabolized into a smaller polymer and a monomer by means of a hydrolysis reaction. Hydrocarbon - Describes a particular structure that is composed exclusively of carbons and hydrogens. (Figure 7) Figure 7. A molecule of pentane, which is also classified as a hydrocarbon. 8. Hyper Root, Prefix or Suffix: Prefix Origin: Greek Literal Translation: Over; Excessive Example: Hypertonic - Describes a solution that has a higher (excessive) solute concentration compared to that of another solution. (Figure 8) Figure 8. A bag containing a 10% NaCl solution is placed in a beaker containing a 20% NaCl solution. In this particular example, the solution in the beaker is hypertonic to the solution in the bag because the NaCl concentration is higher in the beaker than in the bag. Hyperactive - Can describe the polypeptide(s) that have been produced from a mutated gene(s) than now exhibit unregulated or excessive activity. (Figure 9) Figure 9. Development of a hyperactive form of a particular protein due to a mutation in the genetic material. 9. Hypo Root, Prefix or Suffix: Prefix Origin: Greek Literal Translation: Under; Below Example: Hypotonic - Describes a solution that has a lower solute concentration compared to that of another solution. Its solute concentration is below that of the other solution’s. (Figure 10) Figure 10. A bag containing a 10% NaCl solution is placed in a beaker containing a 20% NaCl solution. In this particular example, the solution in the bag is hypotonic to the solution in the beaker because the NaCl concentration is lower in the bag than in the beaker. 10. Ic Root, Prefix or Suffix: Suffix Origin: Greek Literal Translation: Of, relating to, or characterized by Example: Hydrophilic - Term used to describe a molecule that is characterized by its affinity for water. 11. Iso Root, Prefix or Suffix: Prefix Origin: Greek Literal Translation: Equal; Similar Example: Isotonic - Describes a solution that has an equal solute concentration compared to that of another solution. (Figure 11) Figure 11. A bag containing a 20% NaCl solution is placed in a beaker containing a 20% NaCl solution. In this particular example, the two solutions are isotonic to one another. Isomer - Describes two molecules that have the same molecule formula, but different structures. (Figure 12) Figure 12. Structural isomers that have the same chemical formula of C5H12 but a different covalent structure. Isotope - Describes an atom of a particular element that has the same number of protons in its nucleus, and therefore the same atomic number, but has a different number of neutrons, which alters its mass. 12. Karyote Root, Prefix or Suffix: Suffix Origin: Greek Literal Translation: Nut; Kernel Example: Eukaryote - An organism that has cells with membrane bound organelles, and genetic material that is housed in a nucleus. (in this case that can be taken to mean that the nucleus represent the kernel of the cell, much like the kernel at the center of a piece of popped popcorn). 13. Lysis Root, Prefix or Suffix: Suffix Origin: Greek Literal Translation: Loosen, Release Example: Hydrolysis - Chemical reaction where a water is split (its bonds are loosened or released) as a means of catabolizing a compound. Figure 13. A larger polymer is catabolized into a smaller polymer and a monomer by means of a hydrolysis reaction. Lysis - Occurs when a virus invades a cell and hijack the cell machinery to produce new viral particles until the internal pressure of the cell is too great. At this point in time the cell lyses or bursts, which occurs because the membrane loosens and eventually allows all of the cell contents and new viral particles to escape. (Figure 14) Figure 14. The viral lytic cycle wherein a virus invades a cell, and, when enough new viruses have been assembled, the cell lyses releasing them. 14. Macro Root, Prefix or Suffix: Prefix Origin: Greek Literal Translation: Long Example: Macromolecule - Larger or longer biological molecules that are built from smaller subunits. 15. Mer Root, Prefix or Suffix: Suffix Origin: Greek Literal Translation: Unit, Part, Portion Example: Monomer - A single subunit or part of a larger molecule or biological structure. Isomer - Describes two molecules or units that have the same molecule formula, but different structures. 16. Meta/Metabol Root, Prefix or Suffix: Prefix Origin: Greek Literal Translation: Change, Alteration Example: Metabolism - The combination of anabolic and catabolic processes that help to maintain an organism’s homeostasis. (Anabolic and Catabolic processes result in changes to molecular structures and the transformation between energy states) 17. Micro Root, Prefix or Suffix: Prefix Origin: Greek Literal Translation: Small Example: Microbiology - The study of very small organisms. 18. Mono Root, Prefix or Suffix: Prefix Origin: Greek Literal Translation: Alone, Single, One Example: Monomers - Single subunit of a larger unit or molecule. (Figure 15) Monosaccharide - Single sugar structure such as Glucose. (Figure 15) Figure 15. A polysaccharide is shown. The molecule within the confines of the red box represents one of the glucose monomers that composes this larger polymer. Furthermore, this glucose molecule is classified as a monosaccharide. 19. Ose Root, Prefix or Suffix: Prefix Origin: Latin Literal Translation: Full of; Denotes a Carbohydrate Example: Glucose - Six carbon sugar (carbohydrate) that is metabolized during glycolysis and fermentation. Glu actually translates to Sweet, so the word glucose translates to Full of Sweet. (Figure 16) Sugar Amylose Deoxyribose Fructose Glucose Lactose Maltose Ribose Sucrose Figure 16. List of various sugars ending with “ose.” Note that not all sugars or carbohydrates will end with “ose,” but if a word in a biological context does end with “ose,” it is most likely a carbohydrate/sugar. 20. Peptide Root, Prefix or Suffix: Root Origin: 1905-1910 Literal Translation: Refers to any compound that is composed of two or more amino acids joined by bonds between their carboxyl and amino groups Example: Polypeptide - A subunit of a protein that is composed of a chain of amino acids 21. Philic Root, Prefix or Suffix: Suffix Origin: Greek Literal Translation: To love; Loving Example: Hydrophilic - Describes any molecule, compound or particle that has an affinity (loves) for water. 22. Phobic Root, Prefix or Suffix: Suffix Origin: Greek Literal Translation: To fear Example: Hydrophobic - Describes any molecule, compound or particle that does not have an affinity for (fears) water 23. Photo Root, Prefix or Suffix: Prefix Origin: Greek Literal Translation: Light Example: Photosynthesis - Process that converts light energy to chemical energy (glucose precursor). (Figure 17) Figure 17. Diagram that depicts the process of photosynthesis as it occurs throughout the chloroplast and acts to convert light energy to chemical energy. 24. Polar Root, Prefix or Suffix: Prefix Origin: Latin, Greek Literal Translation: Axis, Pole Example: Polar Covalent Bond - A covalent bond wherein electrons are shared unevenly due to a large enough difference in electronegativities of the two atoms involved in the bond. The result is that the molecule containing this bond may have a pole with a slight negative charge, and a pole with a slight positive charge. (Figure 18) Figure 18. Water is a polar molecule due to the uneven way that oxygen and hydrogen share electrons. 25. Poly Root, Prefix or Suffix: Prefix Origin: Greek Literal Translation: Many, Much Example: Polymer - A molecule made from many smaller subunits. Polysaccharide - A carbohydrate made from many (three or more) monosaccharides. (Figure 19) Figure 19. The polysaccharide shown is composed from many monosaccharides, making it a polymer. 26. Pro Root, Prefix or Suffix: Prefix Origin: Greek Literal Translation: Before Example: Prokaryote / Prokaryotic - An organism that has cells without membrane bound organelles, and its genetic material exists in an undefined nuclear region of the cytoplasm. Karyote actually translates to nut or kernel (in this case that can be taken to mean that the nucleus acts as the kernel of the cell). So, the term literally translates to before nucleus. 27. Saccharide Root, Prefix or Suffix: Prefix Origin: Greek Literal Translation: Sugar Example: Monosaccharide - A single sugar. 28. Synthesis Root, Prefix or Suffix: Prefix, Root & Suffix Origin: Greek Literal Translation: Syn means with or together; the means to put or place, sis means the action of Example: Protein Synthesis - The action of putting together smaller subunits to make a protein. (Figure 20) Figure 20. Shows the synthesis of a protein as it occurs during translation at the ribosome. 29. Tonic/Tonicity Root, Prefix or Suffix: Prefix Origin: Greek Literal Translation: The Osmotic Pressure of a Solution Example: Isotonic - Instance where the osmotic pressure of a solution is equal to that of another solution (solute concentrations are equal) 30. Trans Root, Prefix or Suffix: Prefix Origin: Latin Literal Translation: Across, Beyond Example: Can be used to denote the spatial arrangement of a geometric isomer wherein the atom(s) of interest that are attached to either of the carbons lie on opposite sides of the isomer (they are across from one another). (Figure 21) Figure 21. Geometric isomer in the cis orientation. 31. Valence Root, Prefix or Suffix: Prefix Origin: Latin Literal Translation: To be strong; Strenght Example: Valence Shell - The outer most shell of an atom containing electrons. The electrons in the valence shell of an atom will have the highest level of potential energy of all the electrons in that atom (their potential energy will be the strongest). (Figure 22) Figure 22. An atom of oxygen is shown will all of its total number of electrons occupying two shells. The outermost shell in the diagram represents the valence shell. References: 1. (2011). In Dictionary.com. Retrieved July 16, 2011, from Dictionary.reference.com All prefixes, suffixes, and root meanings for this document were obtained by using Dictionary.com. This document is intended for educational purposes only, and is not meant to be reproduced or sold for any purpose.