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Somatosensory information from the limbs and trunk is conveyed to the thalamus and cerebral cortex by two ascending pathways. Brain slices along the
neuraxis from the spinal cord to the cerebrum illustrate the anatomy of the two principal pathways conveying somatosensory information to the cerebral
cortex. The two pathways are separated until they reach the pons, where they are juxtaposed.
Dorsal column—medial lemniscal system. Tactile and limb proprioception signals are conveyed to the spinal cord and brain stem by large-diameter
myelinated fibers and transmitted to the thalamus in this system. In the spinal cord the fibers for touch and proprioception divide, one branch going to the
spinal gray matter
other ascendingSystem:
in the ipsilateral
to the medulla.
The second-order
fibers Fifth
from Editon
the dorsal column nuclei cross the
and Central
of Neural Science,
midline in the medulla and ascend in the medial lemniscus toward the thalamus, where they terminate in the lateral and medial ventral posterior nuclei.
Citation: Kandel ER, Schwartz JH, Jessell TM, Siegelbaum SA, Hudspeth AJ, Mack S. Principles of Neural Science, Fifth Editon; 2012 Available
These nuclei convey tactile and proprioceptive information to the primary somatic sensory cortex.
at: Accessed: June 11, 2017
system. Pain,
and visceral
© 2017
All rights
reservedis conveyed to the spinal cord by small-diameter myelinated and unmyelinated
fibers that terminate in the dorsal horn. This information is conveyed across the midline within the spinal cord and transmitted to the brain stem and the