Survey
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Download Monday Oct
Document related concepts
no text concepts found
Transcript
19 October 2009 Approaching Fall Break! This Week in Physiology: Wednesday Quiz: Cranial Nerves Lab: Sensory Physiology & Auditory System Lectures: Ch. 9 Muscle Physiology Characteristics: Location, cell shape, nuclei per cell, innervation, arrangement of actin and myosin, regulation of cross bridges, sources of Ca++, etc. Different types of muscles for different tasks! Synonyms: NMJ = neuromuscular junction Fig. 09.14 Myoneural junction Motor end plate 1 AP in motor axon releases sufficient ACh for 1 AP in skeletal muscle Fig. 09.15 Nicotinic Fig. 09.14 Fig. 09.01a Capillaries ??? How does AP in sarcolemma cause twitch??? Terms: Myofiber, myofibril, myofilament Fig. 09.11b Thick myofilament = myosin Thin myofilament = actin Fig. 09.11a Fig. 09.12 The concentration of free calcium is directly related to force of contraction in skeletal muscle Thus we need to understand the cellular mechanism of contraction… cell biology flashbacks… Fig. 09.02 dArk band = aligned myosin filaments lIght band = absence of myosin filaments Fig. 09.03 Fig. 09.04 Fig. 09.05a Fig. 09.05b Contracted Fig. 09.06 Fig. 09.07 Fig. 09.08 2 roles of ATP: Energy for powerstroke & Necessary for detaching myosin from actin Crossbridge cycling continues as long as ATP and Ca++ present. Fig. 09.09 Muscle kinetics Link to cytosolic calcium concentration, release, and reuptake?
